1HK4 | Genus

Total Genus 225

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	225
sequence length	582
structure length	582
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Plasma protein
source organism	Homo sapiens
publication title	Structural Basis of Albumin-Thyroxine Interactions and Familial Dysalbuminemic Hyperthyroxinemia pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	225
structure length	582
sequence length	582
ec nomenclature
pdb deposition date	2003-03-05

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1hk4A03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1hk4A02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1hk4A04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1hk4A01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1hk4A06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1hk4A05

2BXPA 2BXHA 4PO0A 4Z69A 2YDFA 4LUHA 4E99A 4BKEA 1O9XA 4L8UA 5GHKA 1BM0A 1BKEA 4N0UD 2BXOA 2XVUA 1HK5A 2XVQA 1GNJA 5DBYA 1E7AA 1E7BA 1GNIA 1HA2A 2BXQA 1HK4A 4OR0A 1N5UA 2VUEA 3CX9A 5ID7A 4L9QA 2XVVA 4G03A 2BX8A 3JQZA 3TDLA 4F5SA 3JRYA 4G04A 3LU8A 3B9MA 1E7HA 5IFOA 2XSIA 5HOZA 5IJEA 4L9KA 4S1YA 3UIVA 3V03A 5IIHA 1UORA 4ZBQA 2BXCA 1E7CA 2BXMA 1MA9A 2BXKA 4JK4A 1KXPD 4F5UA 4LUFA 4LB9A 1HK1A 5ID9A 1E7EA 2XW1A 1J7EA 4LA0A 2BXFA 5IJ5A 1E78A 2BXLA 2BXDA 2XVWA 2BXNA 2BXGA 4K2CA 1KW2A 2BXAA 1TF0A 5IJFA 4OT2A 2I30A 3B9LA 3LU7A 4K71A 1E7IA 2VUFA 4F5TA 5DQFA 1E7FA 3SQJA 4HGMB 4N0FD 1AO6A 3V09A 2I2ZA 4J2VA 5FUOA 5IIUA 2BXEA 3LU6A 4EMXA 4F5VA 1LOTA 2XW0A 1BJ5A 3V08A 4IW1A 2VDBA 5IIXA 4LB2A 3A73A 2BXBA 1HK2A 4HGKA 1H9ZA 1J78A 1E7GA 4ZBRA 2BXIA 1HK3A 4IW2A
chains in the Genus database with same CATH superfamily

1FOUA 2BXPA 5BPKA 2BXHA 4PO0A 4DHXB 3WHRA 2YDFA 3GQUA 4TQ1A 4Z69A 4GG2A 2NNWA 4LUHA 4E99A 4MBEC 4BKEA 1O9XA 4FIPB 4L8UA 4NAWB 5GHKA 1BM0A 1BKEA 3A75A 2NQOA 3KJLA 2AGHB 2BXOA 2LOQA 3MHHB 2XVUA 1HK5A 3H37A 4N0UD 3NMUA 3SIVB 2XVQA 1GNJA 2DYMA 2EFDA 1VFIA 5DBYA 1E7AA 1E7BA 5GINA 1GNIA 1HA2A 4I9OA 3ICXA 4GDKB 2BXQA 1HK4A 4OR0A 3PLAA 1N5UA 2LXTA 2VUEA 4TQ0A 3CX9A 5ID7A 4L9QA 3FWBC 2XVVA 4Z9OA 4G03A 2BX8A 3JQZA 4GDLB 4OTUA 3TDLA 4F5SA 3NVKA 3JRYA 4G04A 3LU8A 3G9KD 2JUHA 2LQHA 3B9MA 1E7HA 5IFOA 2XSIA 5HOZA 5IJEA 3H3AA 1MIVA 4L9KA 1SB0A 4OTTA 4S1YA 3UIVA 3V03A 3VQIA 5IIHA 1UORA 4ZBQA 4G01A 1NT2B 2GUTA 3GA9L 2CKXA 2BXCA 1E7CA 2BXMA 1MA9A 2BXKA 4JK4A 1KXPD 4F5UA 2EFHA 4LUFA 5D7GA 4LB9A 1HK1A 2DBXA 5ID9A 1E7EA 1MUHA 1VZSA 2XW1A 2V36A 1MIWA 5GIOA 1J7EA 4LA0A 2KWFA 4D7XA 4FK5B 2E0XA 2BXFA 5IJ5A 1E78A 4M70B 4ZBKA 3NVIA 3BPJA 2BXLA 2BXDA 2OZBB 2QHBA 2Z8KA 4ZC6A 2XVWA 2BXNA 2BXGA 2QM6A 3FWCC 1KDXA 4K2CA 1KW2A 2BXAA 4BY9C 5B5TA 1TF0A 1MUSA 3MHSB 5IJFA 4N3ZA 1LNSA 1IJGA 2DBUA 4OT2A 5GIPA 4ZCGA 2I30A 3B9LA 3LU7A 3FNMA 4K71A 1E7IA 2VUFA 4W4UB 2ROHA 4F5TA 2DYOA 5DQFA 1E7FA 2Z8IA 3SQJA 4HGMB 2Z8JA 4N0FD 1AO6A 3V09A 2KBZA 3SIUB 2I2ZA 1H5WA 4J2VA 4GDXA 2EFEA 5FUOA 2DG5A 3ECPA 2E0YA 2EFCA 5IIUA 2BXEA 3WHSA 4DM0A 1MIYA 3LU6A 4EMXA 4F5VA 1LOTA 2XW0A 3M99C 3WHQA 1BJ5A 2AJEA 4C31B 2K0NA 4ZUXV 1JNBA 2QMCA 3KIKA 3V08A 4IW1A 2VDBA 4WA6B 5IIXA 2OT3A 3GQXA 3W1SA 4LB2A 1MM8A 2XMOA 3A73A 3NVMA 1TXUA 2BXBA 1HK2A 4HGKA 1H9ZA 1J78A 2DBWA 4FJCB 1E7GA 4ZBRA 2BXIA 2LXSA 1HK3A 2LQIA 4IW2A
chains in the Genus database with same CATH topology

1FOUA 2BXPA 5BPKA 2BXHA 4PO0A 4DHXB 3WHRA 2YDFA 3GQUA 4TQ1A 4Z69A 4GG2A 2NNWA 4LUHA 4E99A 4MBEC 4BKEA 1O9XA 4FIPB 4L8UA 4NAWB 5GHKA 1BM0A 1BKEA 3A75A 2NQOA 3KJLA 4N0UD 2BXOA 2LOQA 3MHHB 2XVUA 1HK5A 3H37A 3NMUA 3SIVB 2XVQA 1GNJA 2DYMA 2EFDA 1VFIA 5DBYA 1E7AA 1E7BA 5GINA 1GNIA 1HA2A 3ICXA 4GDKB 2BXQA 1HK4A 4OR0A 3PLAA 1N5UA 2VUEA 4TQ0A 3CX9A 5ID7A 4L9QA 3FWBC 2XVVA 4Z9OA 4G03A 2BX8A 3JQZA 4GDLB 4OTUA 3TDLA 4F5SA 3NVKA 3JRYA 4G04A 3LU8A 3G9KD 2JUHA 3B9MA 1E7HA 5IFOA 2XSIA 5HOZA 5IJEA 3H3AA 1MIVA 4L9KA 4OTTA 4S1YA 3UIVA 3V03A 3VQIA 5IIHA 1UORA 4ZBQA 4G01A 1NT2B 3GA9L 2CKXA 2BXCA 1E7CA 2BXMA 1MA9A 2BXKA 4JK4A 1KXPD 4F5UA 2EFHA 4LUFA 5D7GA 4LB9A 1HK1A 2DBXA 5ID9A 1E7EA 1VZSA 2XW1A 2V36A 1MIWA 5GIOA 1J7EA 4LA0A 4FK5B 2E0XA 2BXFA 5IJ5A 1E78A 4M70B 4ZBKA 3NVIA 2BXLA 2BXDA 2OZBB 2QHBA 2Z8KA 4ZC6A 2XVWA 2BXNA 2BXGA 2QM6A 3FWCC 4K2CA 1KW2A 2BXAA 4BY9C 5B5TA 1TF0A 3MHSB 5IJFA 4N3ZA 1LNSA 1IJGA 2DBUA 4OT2A 5GIPA 4ZCGA 2I30A 3B9LA 3LU7A 3FNMA 4K71A 1E7IA 2VUFA 4W4UB 2ROHA 4F5TA 2DYOA 5DQFA 1E7FA 2Z8IA 3SQJA 4HGMB 2Z8JA 4N0FD 1AO6A 3V09A 2KBZA 3SIUB 2I2ZA 1H5WA 4J2VA 4GDXA 2EFEA 5FUOA 2DG5A 2E0YA 2EFCA 5IIUA 2BXEA 3WHSA 1MIYA 3LU6A 4EMXA 4F5VA 1LOTA 2XW0A 3M99C 3WHQA 1BJ5A 2AJEA 4C31B 4ZUXV 1JNBA 2QMCA 3KIKA 3V08A 4IW1A 2VDBA 4WA6B 5IIXA 2OT3A 3GQXA 3W1SA 4LB2A 2XMOA 3A73A 3NVMA 1TXUA 2BXBA 1HK2A 4HGKA 1H9ZA 1J78A 2DBWA 4FJCB 1E7GA 4ZBRA 2BXIA 1HK3A 4IW2A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2BXP A;  2BXH A;  4PO0 A;  4Z69 A;  2YDF A;  4LUH A;  4E99 A;  4BKE A;  1O9X A;  4L8U A;  5GHK A;  1BM0 A;  1BKE A;  4N0U D;  2BXO A;  2XVU A;  1HK5 A;  2XVQ A;  1GNJ A;  5DBY A;  1E7A A;  1E7B A;  1GNI A;  1HA2 A;  2BXQ A;  1HK4 A;  4OR0 A;  1N5U A;  2VUE A;  3CX9 A;  5ID7 A;  4L9Q A;  2XVV A;  4G03 A;  2BX8 A;  3JQZ A;  3TDL A;  4F5S A;  3JRY A;  4G04 A;  3LU8 A;  3B9M A;  1E7H A;  5IFO A;  2XSI A;  5HOZ A;  5IJE A;  4L9K A;  4S1Y A;  3UIV A;  3V03 A;  5IIH A;  1UOR A;  4ZBQ A;  2BXC A;  1E7C A;  2BXM A;  1MA9 A;  2BXK A;  4JK4 A;  1KXP D;  4F5U A;  4LUF A;  4LB9 A;  1HK1 A;  5ID9 A;  1E7E A;  2XW1 A;  1J7E A;  4LA0 A;  2BXF A;  5IJ5 A;  1E78 A;  2BXL A;  2BXD A;  2XVW A;  2BXN A;  2BXG A;  4K2C A;  1KW2 A;  2BXA A;  1TF0 A;  5IJF A;  4OT2 A;  2I30 A;  3B9L A;  3LU7 A;  4K71 A;  1E7I A;  2VUF A;  4F5T A;  5DQF A;  1E7F A;  3SQJ A;  4HGM B;  4N0F D;  1AO6 A;  3V09 A;  2I2Z A;  4J2V A;  5FUO A;  5IIU A;  2BXE A;  3LU6 A;  4EMX A;  4F5V A;  1LOT A;  2XW0 A;  1BJ5 A;  3V08 A;  4IW1 A;  2VDB A;  5IIX A;  4LB2 A;  3A73 A;  2BXB A;  1HK2 A;  4HGK A;  1H9Z A;  1J78 A;  1E7G A;  4ZBR A;  2BXI A;  1HK3 A;  4IW2 A; 
#chains in the Genus database with same CATH topology
 1FOU A;  2BXP A;  5BPK A;  2BXH A;  4PO0 A;  4DHX B;  3WHR A;  2YDF A;  3GQU A;  4TQ1 A;  4Z69 A;  4GG2 A;  2NNW A;  4LUH A;  4E99 A;  4MBE C;  4BKE A;  1O9X A;  4FIP B;  4L8U A;  4NAW B;  5GHK A;  1BM0 A;  1BKE A;  3A75 A;  2NQO A;  3KJL A;  2AGH B;  2BXO A;  2LOQ A;  3MHH B;  2XVU A;  1HK5 A;  3H37 A;  4N0U D;  3NMU A;  3SIV B;  2XVQ A;  1GNJ A;  2DYM A;  2EFD A;  1VFI A;  5DBY A;  1E7A A;  1E7B A;  5GIN A;  1GNI A;  1HA2 A;  4I9O A;  3ICX A;  4GDK B;  2BXQ A;  1HK4 A;  4OR0 A;  3PLA A;  1N5U A;  2LXT A;  2VUE A;  4TQ0 A;  3CX9 A;  5ID7 A;  4L9Q A;  3FWB C;  2XVV A;  4Z9O A;  4G03 A;  2BX8 A;  3JQZ A;  4GDL B;  4OTU A;  3TDL A;  4F5S A;  3NVK A;  3JRY A;  4G04 A;  3LU8 A;  3G9K D;  2JUH A;  2LQH A;  3B9M A;  1E7H A;  5IFO A;  2XSI A;  5HOZ A;  5IJE A;  3H3A A;  1MIV A;  4L9K A;  1SB0 A;  4OTT A;  4S1Y A;  3UIV A;  3V03 A;  3VQI A;  5IIH A;  1UOR A;  4ZBQ A;  4G01 A;  1NT2 B;  2GUT A;  3GA9 L;  2CKX A;  2BXC A;  1E7C A;  2BXM A;  1MA9 A;  2BXK A;  4JK4 A;  1KXP D;  4F5U A;  2EFH A;  4LUF A;  5D7G A;  4LB9 A;  1HK1 A;  2DBX A;  5ID9 A;  1E7E A;  1MUH A;  1VZS A;  2XW1 A;  2V36 A;  1MIW A;  5GIO A;  1J7E A;  4LA0 A;  2KWF A;  4D7X A;  4FK5 B;  2E0X A;  2BXF A;  5IJ5 A;  1E78 A;  4M70 B;  4ZBK A;  3NVI A;  3BPJ A;  2BXL A;  2BXD A;  2OZB B;  2QHB A;  2Z8K A;  4ZC6 A;  2XVW A;  2BXN A;  2BXG A;  2QM6 A;  3FWC C;  1KDX A;  4K2C A;  1KW2 A;  2BXA A;  4BY9 C;  5B5T A;  1TF0 A;  1MUS A;  3MHS B;  5IJF A;  4N3Z A;  1LNS A;  1IJG A;  2DBU A;  4OT2 A;  5GIP A;  4ZCG A;  2I30 A;  3B9L A;  3LU7 A;  3FNM A;  4K71 A;  1E7I A;  2VUF A;  4W4U B;  2ROH A;  4F5T A;  2DYO A;  5DQF A;  1E7F A;  2Z8I A;  3SQJ A;  4HGM B;  2Z8J A;  4N0F D;  1AO6 A;  3V09 A;  2KBZ A;  3SIU B;  2I2Z A;  1H5W A;  4J2V A;  4GDX A;  2EFE A;  5FUO A;  2DG5 A;  3ECP A;  2E0Y A;  2EFC A;  5IIU A;  2BXE A;  3WHS A;  4DM0 A;  1MIY A;  3LU6 A;  4EMX A;  4F5V A;  1LOT A;  2XW0 A;  3M99 C;  3WHQ A;  1BJ5 A;  2AJE A;  4C31 B;  2K0N A;  4ZUX V;  1JNB A;  2QMC A;  3KIK A;  3V08 A;  4IW1 A;  2VDB A;  4WA6 B;  5IIX A;  2OT3 A;  3GQX A;  3W1S A;  4LB2 A;  1MM8 A;  2XMO A;  3A73 A;  3NVM A;  1TXU A;  2BXB A;  1HK2 A;  4HGK A;  1H9Z A;  1J78 A;  2DBW A;  4FJC B;  1E7G A;  4ZBR A;  2BXI A;  2LXS A;  1HK3 A;  2LQI A;  4IW2 A; 
#chains in the Genus database with same CATH homology
 1FOU A;  2BXP A;  5BPK A;  2BXH A;  4PO0 A;  4DHX B;  3WHR A;  2YDF A;  3GQU A;  4TQ1 A;  4Z69 A;  4GG2 A;  2NNW A;  4LUH A;  4E99 A;  4MBE C;  4BKE A;  1O9X A;  4FIP B;  4L8U A;  4NAW B;  5GHK A;  1BM0 A;  1BKE A;  3A75 A;  2NQO A;  3KJL A;  4N0U D;  2BXO A;  2LOQ A;  3MHH B;  2XVU A;  1HK5 A;  3H37 A;  3NMU A;  3SIV B;  2XVQ A;  1GNJ A;  2DYM A;  2EFD A;  1VFI A;  5DBY A;  1E7A A;  1E7B A;  5GIN A;  1GNI A;  1HA2 A;  3ICX A;  4GDK B;  2BXQ A;  1HK4 A;  4OR0 A;  3PLA A;  1N5U A;  2VUE A;  4TQ0 A;  3CX9 A;  5ID7 A;  4L9Q A;  3FWB C;  2XVV A;  4Z9O A;  4G03 A;  2BX8 A;  3JQZ A;  4GDL B;  4OTU A;  3TDL A;  4F5S A;  3NVK A;  3JRY A;  4G04 A;  3LU8 A;  3G9K D;  2JUH A;  3B9M A;  1E7H A;  5IFO A;  2XSI A;  5HOZ A;  5IJE A;  3H3A A;  1MIV A;  4L9K A;  4OTT A;  4S1Y A;  3UIV A;  3V03 A;  3VQI A;  5IIH A;  1UOR A;  4ZBQ A;  4G01 A;  1NT2 B;  3GA9 L;  2CKX A;  2BXC A;  1E7C A;  2BXM A;  1MA9 A;  2BXK A;  4JK4 A;  1KXP D;  4F5U A;  2EFH A;  4LUF A;  5D7G A;  4LB9 A;  1HK1 A;  2DBX A;  5ID9 A;  1E7E A;  1VZS A;  2XW1 A;  2V36 A;  1MIW A;  5GIO A;  1J7E A;  4LA0 A;  4FK5 B;  2E0X A;  2BXF A;  5IJ5 A;  1E78 A;  4M70 B;  4ZBK A;  3NVI A;  2BXL A;  2BXD A;  2OZB B;  2QHB A;  2Z8K A;  4ZC6 A;  2XVW A;  2BXN A;  2BXG A;  2QM6 A;  3FWC C;  4K2C A;  1KW2 A;  2BXA A;  4BY9 C;  5B5T A;  1TF0 A;  3MHS B;  5IJF A;  4N3Z A;  1LNS A;  1IJG A;  2DBU A;  4OT2 A;  5GIP A;  4ZCG A;  2I30 A;  3B9L A;  3LU7 A;  3FNM A;  4K71 A;  1E7I A;  2VUF A;  4W4U B;  2ROH A;  4F5T A;  2DYO A;  5DQF A;  1E7F A;  2Z8I A;  3SQJ A;  4HGM B;  2Z8J A;  4N0F D;  1AO6 A;  3V09 A;  2KBZ A;  3SIU B;  2I2Z A;  1H5W A;  4J2V A;  4GDX A;  2EFE A;  5FUO A;  2DG5 A;  2E0Y A;  2EFC A;  5IIU A;  2BXE A;  3WHS A;  1MIY A;  3LU6 A;  4EMX A;  4F5V A;  1LOT A;  2XW0 A;  3M99 C;  3WHQ A;  1BJ5 A;  2AJE A;  4C31 B;  4ZUX V;  1JNB A;  2QMC A;  3KIK A;  3V08 A;  4IW1 A;  2VDB A;  4WA6 B;  5IIX A;  2OT3 A;  3GQX A;  3W1S A;  4LB2 A;  2XMO A;  3A73 A;  3NVM A;  1TXU A;  2BXB A;  1HK2 A;  4HGK A;  1H9Z A;  1J78 A;  2DBW A;  4FJC B;  1E7G A;  4ZBR A;  2BXI A;  1HK3 A;  4IW2 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1HK4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations