1J7EA

A structural basis for the unique binding features of the human vitamin d-binding protein
Total Genus 159
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
451
structure length
435
Chain Sequence
YEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCDTRTSALSAKSCSPFPVHPGTAECCTKRKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A structural basis for the unique binding features of the human vitamin D-binding protein.
pubmed doi rcsb
molecule tags Transport, ligand binding protein
molecule keywords vitamin D binding protein
total genus 159
structure length 435
sequence length 451
chains with identical sequence B
ec nomenclature
pdb deposition date 2001-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
A PF09164 VitD-bind_III Vitamin D binding protein, domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA05
2BXIA 2XVWA 2BXMA 1HA2A 2BXDA 3A73A 4K2CA 2XW1A 1GNJA 5DQFA 3CX9A 3V03A 5DBYA 3JRYA 1E7BA 4L8UA 1AO6A 2BXNA 5IIUA 1UORA 1HK5A 2BXEA 5IIXA 5IFOA 4LB9A 2I30A 1BKEA 1BM0A 1BJ5A 3LU7A 2BXKA 4L9QA 4S1YA 4F5SA 1O9XA 4N0UD 4IW1A 4LB2A 2BXHA 4HGKA 3LU8A 4L9KA 1HK2A 4BKEA 4OT2A 2VUEA 1E7GA 3B9MA 5GHKA 2BXPA 2XVQA 3SQJA 4G04A 2BXGA 4PO0A 1KXPD 2I2ZA 4F5VA 4F5UA 4ZBQA 1LOTA 1E7IA 2YDFA 2XVUA 2BX8A 1HK3A 1GNIA 2BXAA 1H9ZA 2BXOA 2VDBA 4LUFA 4E99A 3TDLA 3LU6A 5IIHA 1J7EA 2BXLA 2XW0A 1KW2A 3JQZA 4HGMB 4Z69A 1HK4A 1E7FA 4LA0A 2XSIA 5ID7A 4G03A 4J2VA 3V08A 5IJ5A 4LUHA 2BXQA 4IW2A 5IJEA 4JK4A 1E78A 5IJFA 2VUFA 1HK1A 4ZBRA 2BXCA 4K71A 2XVVA 1N5UA 4F5TA 1TF0A 3UIVA 4EMXA 1E7HA 1E7CA 3V09A 5ID9A 4OR0A 4N0FD 5HOZA 1J78A 1MA9A 1E7AA 2BXBA 5FUOA 1E7EA 2BXFA 3B9LA
chains in the Genus database with same CATH superfamily
3BPJA 2BXIA 2XVWA 1HA2A 2KWFA 3SIUB 2BXDA 2NNWA 3A73A 4K2CA 2Z8KA 3G9KD 2XW1A 1GNJA 5DQFA 3CX9A 2EFDA 2LXSA 3V03A 1H5WA 4MBEC 5DBYA 4DHXB 3JRYA 1E7BA 4L8UA 1TXUA 1AO6A 2BXNA 5D7GA 2E0YA 5IIUA 1UORA 2DBXA 1HK5A 3B9LA 3A75A 2BXEA 2KBZA 5IIXA 4ZC6A 2JUHA 4G01A 3GQUA 3M99C 5IFOA 1SB0A 4Z9OA 4LB9A 5GIOA 4GG2A 2I30A 3NVIA 2LXTA 1NT2B 2AGHB 1BM0A 1BKEA 3WHSA 1BJ5A 3LU7A 2BXKA 5B5TA 4L9QA 4S1YA 2QM6A 2OZBB 4F5SA 1O9XA 3H37A 3FWBC 4N0UD 4IW1A 2Z8JA 2XMOA 4LB2A 1MM8A 1FOUA 2BXHA 4HGKA 2EFCA 3LU8A 4L9KA 1HK2A 2GUTA 4BKEA 4OT2A 3NMUA 4TQ0A 2VUEA 1E7GA 3B9MA 1IJGA 5GHKA 3NVKA 2BXPA 2XVQA 3SQJA 4G04A 2DBWA 1MIYA 2BXGA 4PO0A 1KXPD 2I2ZA 3FNMA 4F5VA 4F5UA 4ZBQA 2QHBA 1LOTA 1E7IA 1KDXA 4DM0A 2YDFA 2XVUA 2BX8A 4ZBKA 1HK3A 2DYMA 1MIVA 1GNIA 2BXAA 1H9ZA 2BXOA 2OT3A 2VDBA 3H3AA 2ROHA 3MHHB 4LUFA 3TDLA 4E99A 2AJEA 3WHRA 3LU6A 3KIKA 5IIHA 3WHQA 4C31B 1MUSA 1J7EA 4FJCB 2BXLA 2XW0A 5GINA 1KW2A 1MIWA 3JQZA 4HGMB 2LOQA 4FK5B 1HK4A 1LNSA 2Z8IA 4Z69A 1E7FA 1VZSA 2XSIA 4FIPB 4I9OA 4LA0A 4ZCGA 3GA9L 2K0NA 2DBUA 4G03A 5ID7A 1VFIA 4J2VA 2EFEA 4TQ1A 3V08A 3ICXA 5IJ5A 2QMCA 4GDLB 2BXQA 4M70B 4LUHA 2E0XA 4IW2A 5IJEA 4JK4A 3FWCC 1E78A 4N3ZA 5IJFA 2VUFA 3NVMA 4GDXA 1HK1A 1MUHA 3MHSB 2BXCA 2DYOA 4GDKB 4ZBRA 4K71A 4NAWB 3PLAA 4D7XA 2XVVA 5GIPA 1N5UA 4F5TA 4BY9C 4ZUXV 1TF0A 3UIVA 4EMXA 1E7HA 1JNBA 1E7CA 2LQHA 3KJLA 3V09A 3VQIA 2NQOA 3W1SA 5BPKA 5ID9A 3ECPA 4OR0A 3SIVB 4WA6B 2EFHA 4N0FD 4W4UB 5HOZA 1J78A 1MA9A 2DG5A 2CKXA 2LQIA 1E7AA 2BXBA 5FUOA 3GQXA 1E7EA 2BXFA 4OTTA 4OTUA 2V36A 2BXMA
chains in the Genus database with same CATH topology
2BXIA 2XVWA 1HA2A 3SIUB 2BXDA 2NNWA 3A73A 4K2CA 2Z8KA 3G9KD 2XW1A 1GNJA 5DQFA 3CX9A 2EFDA 3V03A 1H5WA 4MBEC 5DBYA 4DHXB 3JRYA 1E7BA 4L8UA 1TXUA 1AO6A 2BXNA 5D7GA 2E0YA 5IIUA 1UORA 2DBXA 1HK5A 3B9LA 3A75A 2BXEA 2KBZA 5IIXA 4ZC6A 2JUHA 4G01A 3GQUA 3M99C 5IFOA 4Z9OA 4LB9A 5GIOA 4GG2A 2I30A 3NVIA 1NT2B 1BM0A 1BKEA 3WHSA 1BJ5A 3LU7A 2BXKA 5B5TA 4L9QA 4S1YA 2QM6A 2OZBB 4F5SA 1O9XA 3H37A 3FWBC 4N0UD 4IW1A 2Z8JA 2XMOA 4LB2A 1FOUA 2BXHA 4HGKA 2EFCA 3LU8A 4L9KA 1HK2A 4BKEA 4OT2A 3NMUA 4TQ0A 2VUEA 1E7GA 3B9MA 1IJGA 5GHKA 3NVKA 2BXPA 2XVQA 3SQJA 4G04A 2DBWA 1MIYA 2BXGA 4PO0A 1KXPD 2I2ZA 3FNMA 4F5VA 4F5UA 4ZBQA 2QHBA 1LOTA 1E7IA 2YDFA 2XVUA 2BX8A 4ZBKA 1HK3A 2DYMA 1MIVA 1GNIA 2BXAA 1H9ZA 2BXOA 2OT3A 2VDBA 3H3AA 2ROHA 3MHHB 4LUFA 3TDLA 4E99A 2AJEA 3WHRA 3LU6A 3KIKA 5IIHA 3WHQA 4C31B 1J7EA 4FJCB 2BXLA 2XW0A 5GINA 1KW2A 1MIWA 3JQZA 4HGMB 2LOQA 4FK5B 1HK4A 1LNSA 2Z8IA 4Z69A 1E7FA 1VZSA 2XSIA 4FIPB 4LA0A 4ZCGA 5ID7A 3GA9L 4G03A 2DBUA 1VFIA 4J2VA 2EFEA 4TQ1A 3V08A 3ICXA 5IJ5A 2QMCA 4GDLB 2BXQA 4M70B 4LUHA 2E0XA 4IW2A 5IJEA 4JK4A 3FWCC 1E78A 4N3ZA 5IJFA 2VUFA 3NVMA 4GDXA 1HK1A 3MHSB 2BXCA 2DYOA 4GDKB 4ZBRA 4K71A 4NAWB 3PLAA 2XVVA 5GIPA 1N5UA 4F5TA 4BY9C 4ZUXV 1TF0A 3UIVA 4EMXA 1E7HA 1JNBA 1E7CA 3KJLA 3V09A 3VQIA 3W1SA 2NQOA 5BPKA 5ID9A 3SIVB 4OR0A 4WA6B 2EFHA 4N0FD 4W4UB 5HOZA 1J78A 1MA9A 2DG5A 2CKXA 1E7AA 2BXBA 5FUOA 3GQXA 1E7EA 2BXFA 4OTTA 4OTUA 2V36A 2BXMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXI A;  2XVW A;  2BXM A;  1HA2 A;  2BXD A;  3A73 A;  4K2C A;  2XW1 A;  1GNJ A;  5DQF A;  3CX9 A;  3V03 A;  5DBY A;  3JRY A;  1E7B A;  4L8U A;  1AO6 A;  2BXN A;  5IIU A;  1UOR A;  1HK5 A;  2BXE A;  5IIX A;  5IFO A;  4LB9 A;  2I30 A;  1BKE A;  1BM0 A;  1BJ5 A;  3LU7 A;  2BXK A;  4L9Q A;  4S1Y A;  4F5S A;  1O9X A;  4N0U D;  4IW1 A;  4LB2 A;  2BXH A;  4HGK A;  3LU8 A;  4L9K A;  1HK2 A;  4BKE A;  4OT2 A;  2VUE A;  1E7G A;  3B9M A;  5GHK A;  2BXP A;  2XVQ A;  3SQJ A;  4G04 A;  2BXG A;  4PO0 A;  1KXP D;  2I2Z A;  4F5V A;  4F5U A;  4ZBQ A;  1LOT A;  1E7I A;  2YDF A;  2XVU A;  2BX8 A;  1HK3 A;  1GNI A;  2BXA A;  1H9Z A;  2BXO A;  2VDB A;  4LUF A;  4E99 A;  3TDL A;  3LU6 A;  5IIH A;  1J7E A;  2BXL A;  2XW0 A;  1KW2 A;  3JQZ A;  4HGM B;  4Z69 A;  1HK4 A;  1E7F A;  4LA0 A;  2XSI A;  5ID7 A;  4G03 A;  4J2V A;  3V08 A;  5IJ5 A;  4LUH A;  2BXQ A;  4IW2 A;  5IJE A;  4JK4 A;  1E78 A;  5IJF A;  2VUF A;  1HK1 A;  4ZBR A;  2BXC A;  4K71 A;  2XVV A;  1N5U A;  4F5T A;  1TF0 A;  3UIV A;  4EMX A;  1E7H A;  1E7C A;  3V09 A;  5ID9 A;  4OR0 A;  4N0F D;  5HOZ A;  1J78 A;  1MA9 A;  1E7A A;  2BXB A;  5FUO A;  1E7E A;  2BXF A;  3B9L A; 
#chains in the Genus database with same CATH topology
 3BPJ A;  2BXI A;  2XVW A;  1HA2 A;  2KWF A;  3SIU B;  2BXD A;  2NNW A;  3A73 A;  4K2C A;  2Z8K A;  3G9K D;  2XW1 A;  1GNJ A;  5DQF A;  3CX9 A;  2EFD A;  2LXS A;  3V03 A;  1H5W A;  4MBE C;  5DBY A;  4DHX B;  3JRY A;  1E7B A;  4L8U A;  1TXU A;  1AO6 A;  2BXN A;  5D7G A;  2E0Y A;  5IIU A;  1UOR A;  2DBX A;  1HK5 A;  3B9L A;  3A75 A;  2BXE A;  2KBZ A;  5IIX A;  4ZC6 A;  2JUH A;  4G01 A;  3GQU A;  3M99 C;  5IFO A;  1SB0 A;  4Z9O A;  4LB9 A;  5GIO A;  4GG2 A;  2I30 A;  3NVI A;  2LXT A;  1NT2 B;  2AGH B;  1BM0 A;  1BKE A;  3WHS A;  1BJ5 A;  3LU7 A;  2BXK A;  5B5T A;  4L9Q A;  4S1Y A;  2QM6 A;  2OZB B;  4F5S A;  1O9X A;  3H37 A;  3FWB C;  4N0U D;  4IW1 A;  2Z8J A;  2XMO A;  4LB2 A;  1MM8 A;  1FOU A;  2BXH A;  4HGK A;  2EFC A;  3LU8 A;  4L9K A;  1HK2 A;  2GUT A;  4BKE A;  4OT2 A;  3NMU A;  4TQ0 A;  2VUE A;  1E7G A;  3B9M A;  1IJG A;  5GHK A;  3NVK A;  2BXP A;  2XVQ A;  3SQJ A;  4G04 A;  2DBW A;  1MIY A;  2BXG A;  4PO0 A;  1KXP D;  2I2Z A;  3FNM A;  4F5V A;  4F5U A;  4ZBQ A;  2QHB A;  1LOT A;  1E7I A;  1KDX A;  4DM0 A;  2YDF A;  2XVU A;  2BX8 A;  4ZBK A;  1HK3 A;  2DYM A;  1MIV A;  1GNI A;  2BXA A;  1H9Z A;  2BXO A;  2OT3 A;  2VDB A;  3H3A A;  2ROH A;  3MHH B;  4LUF A;  3TDL A;  4E99 A;  2AJE A;  3WHR A;  3LU6 A;  3KIK A;  5IIH A;  3WHQ A;  4C31 B;  1MUS A;  1J7E A;  4FJC B;  2BXL A;  2XW0 A;  5GIN A;  1KW2 A;  1MIW A;  3JQZ A;  4HGM B;  2LOQ A;  4FK5 B;  1HK4 A;  1LNS A;  2Z8I A;  4Z69 A;  1E7F A;  1VZS A;  2XSI A;  4FIP B;  4I9O A;  4LA0 A;  4ZCG A;  3GA9 L;  2K0N A;  2DBU A;  4G03 A;  5ID7 A;  1VFI A;  4J2V A;  2EFE A;  4TQ1 A;  3V08 A;  3ICX A;  5IJ5 A;  2QMC A;  4GDL B;  2BXQ A;  4M70 B;  4LUH A;  2E0X A;  4IW2 A;  5IJE A;  4JK4 A;  3FWC C;  1E78 A;  4N3Z A;  5IJF A;  2VUF A;  3NVM A;  4GDX A;  1HK1 A;  1MUH A;  3MHS B;  2BXC A;  2DYO A;  4GDK B;  4ZBR A;  4K71 A;  4NAW B;  3PLA A;  4D7X A;  2XVV A;  5GIP A;  1N5U A;  4F5T A;  4BY9 C;  4ZUX V;  1TF0 A;  3UIV A;  4EMX A;  1E7H A;  1JNB A;  1E7C A;  2LQH A;  3KJL A;  3V09 A;  3VQI A;  2NQO A;  3W1S A;  5BPK A;  5ID9 A;  3ECP A;  4OR0 A;  3SIV B;  4WA6 B;  2EFH A;  4N0F D;  4W4U B;  5HOZ A;  1J78 A;  1MA9 A;  2DG5 A;  2CKX A;  2LQI A;  1E7A A;  2BXB A;  5FUO A;  3GQX A;  1E7E A;  2BXF A;  4OTT A;  4OTU A;  2V36 A;  2BXM A; 
#chains in the Genus database with same CATH homology
 2BXI A;  2XVW A;  1HA2 A;  3SIU B;  2BXD A;  2NNW A;  3A73 A;  4K2C A;  2Z8K A;  3G9K D;  2XW1 A;  1GNJ A;  5DQF A;  3CX9 A;  2EFD A;  3V03 A;  1H5W A;  4MBE C;  5DBY A;  4DHX B;  3JRY A;  1E7B A;  4L8U A;  1TXU A;  1AO6 A;  2BXN A;  5D7G A;  2E0Y A;  5IIU A;  1UOR A;  2DBX A;  1HK5 A;  3B9L A;  3A75 A;  2BXE A;  2KBZ A;  5IIX A;  4ZC6 A;  2JUH A;  4G01 A;  3GQU A;  3M99 C;  5IFO A;  4Z9O A;  4LB9 A;  5GIO A;  4GG2 A;  2I30 A;  3NVI A;  1NT2 B;  1BM0 A;  1BKE A;  3WHS A;  1BJ5 A;  3LU7 A;  2BXK A;  5B5T A;  4L9Q A;  4S1Y A;  2QM6 A;  2OZB B;  4F5S A;  1O9X A;  3H37 A;  3FWB C;  4N0U D;  4IW1 A;  2Z8J A;  2XMO A;  4LB2 A;  1FOU A;  2BXH A;  4HGK A;  2EFC A;  3LU8 A;  4L9K A;  1HK2 A;  4BKE A;  4OT2 A;  3NMU A;  4TQ0 A;  2VUE A;  1E7G A;  3B9M A;  1IJG A;  5GHK A;  3NVK A;  2BXP A;  2XVQ A;  3SQJ A;  4G04 A;  2DBW A;  1MIY A;  2BXG A;  4PO0 A;  1KXP D;  2I2Z A;  3FNM A;  4F5V A;  4F5U A;  4ZBQ A;  2QHB A;  1LOT A;  1E7I A;  2YDF A;  2XVU A;  2BX8 A;  4ZBK A;  1HK3 A;  2DYM A;  1MIV A;  1GNI A;  2BXA A;  1H9Z A;  2BXO A;  2OT3 A;  2VDB A;  3H3A A;  2ROH A;  3MHH B;  4LUF A;  3TDL A;  4E99 A;  2AJE A;  3WHR A;  3LU6 A;  3KIK A;  5IIH A;  3WHQ A;  4C31 B;  1J7E A;  4FJC B;  2BXL A;  2XW0 A;  5GIN A;  1KW2 A;  1MIW A;  3JQZ A;  4HGM B;  2LOQ A;  4FK5 B;  1HK4 A;  1LNS A;  2Z8I A;  4Z69 A;  1E7F A;  1VZS A;  2XSI A;  4FIP B;  4LA0 A;  4ZCG A;  5ID7 A;  3GA9 L;  4G03 A;  2DBU A;  1VFI A;  4J2V A;  2EFE A;  4TQ1 A;  3V08 A;  3ICX A;  5IJ5 A;  2QMC A;  4GDL B;  2BXQ A;  4M70 B;  4LUH A;  2E0X A;  4IW2 A;  5IJE A;  4JK4 A;  3FWC C;  1E78 A;  4N3Z A;  5IJF A;  2VUF A;  3NVM A;  4GDX A;  1HK1 A;  3MHS B;  2BXC A;  2DYO A;  4GDK B;  4ZBR A;  4K71 A;  4NAW B;  3PLA A;  2XVV A;  5GIP A;  1N5U A;  4F5T A;  4BY9 C;  4ZUX V;  1TF0 A;  3UIV A;  4EMX A;  1E7H A;  1JNB A;  1E7C A;  3KJL A;  3V09 A;  3VQI A;  3W1S A;  2NQO A;  5BPK A;  5ID9 A;  3SIV B;  4OR0 A;  4WA6 B;  2EFH A;  4N0F D;  4W4U B;  5HOZ A;  1J78 A;  1MA9 A;  2DG5 A;  2CKX A;  1E7A A;  2BXB A;  5FUO A;  3GQX A;  1E7E A;  2BXF A;  4OTT A;  4OTU A;  2V36 A;  2BXM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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