1KEAA

Structure of a thermostable thymine-dna glycosylase
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
217
structure length
217
Chain Sequence
DATNKKRKVFVSTILTFWNTDRRDFPWRHTRDPYVILITEILLRRTTAGHVKKIYDKFFVKYKCFEDILKTPKSEIAKDIKEIGLSNQRAEQLKELARVVINDYGGRVPRNRKAILDLPGVGKYTCAAVMCLAFGKKAAMVDANFVRVINRYFGGSYENLNYNHKALWELAETLVPGGKCRDFNLGLMDFSAIICAPRKPKCEKCGMSKLCSYYEKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Methanothermobacter thermautotrophicus
publication title Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases.
pubmed doi rcsb
molecule keywords Possible G-T mismatches repair enzyme
total genus 78
structure length 217
sequence length 217
ec nomenclature ec 3.2.2.-:
pdb deposition date 2001-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1keaA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1keaA01
1PU6A 3G0QA 4B24A 2JHNA 1KG7A 1KG4A 1N3AA 1LWVA 1WEGA 1P7MA 1WEIA 2JHJA 1LWWA 3FHGA 3F10A 1NKUA 4AI4A 5DPKA 4PIIA 4E9GA 2OFKA 3IH7A 1MUDA 2OFIA 1ORNA 1EBMA 2NOEA 2NOBA 1KEAA 1KO9A 2H56A 4B23A 1KG2A 3CWSA 2XHIA 1XQOA 3I0XA 2JG6A 4E9EA 1PVSA 2NOLA 4AIAA 1HU0A 2NOFA 1M3QA 2YG9A 1XQPA 4YOQA 3OH6A 4DK9A 1DIZA 1FN7A 3KTUA 3CWAA 4HSBA 4EA4A 1PU8A 3OH9A 4EW4A 3OGDA 3N0UA 1KG3A 1N39A 4EA5A 1WEFA 4B21A 4EW0A 3IHOA 1VRLA 1N3CA 1YQLA 2ABKA 3CW7A 1M3HA 4E9FA 2I5WA 1YQRA 4EJYA 1LWYA 1XG7A 1MPGA 4UOBA 4YPHA 1MUNA 4YPRA 3N5NX 4B22A 1ORPA 4UNFA 3FHFA 1RRQA 1KQJA 4OFHA 4AI5A 3FSPA 5KN8A 1KG5A 3S6IA 1PU7A 4EVVA 5AN4A 1KG6A 5CHZA 4E9HA 4OFEA 3I0WA 1P59A 2NOIA 5KN9A 1RRSA 3D4VA 1MUYA 1YQMA 3F0ZA 1YQKA 2NOZA 3CWUA 3CVSA 3CWTA 1NGNA 3CVTA 3KNTA 4EJZA 2NOHA 2YG8A 1LMZA 4OFAA
chains in the Genus database with same CATH superfamily
1PU6A 3G0QA 3OS1A 4B24A 2JHNA 4ZTFA 1KG7A 1KG4A 1N3AA 1LWVA 1WEGA 4BE2A 1P7MA 1WEIA 2JHJA 1LWWA 3FHGA 2W03A 3OYBA 4E7IA 3F10A 1U84A 1NKUA 5FROA 4AI4A 5DPKA 4PIIA 3OYDA 3LCNA 4E9GA 2OFKA 3S3OA 3IH7A 1MUDA 2OFIA 1ORNA 3OS0A 4IKFA 1EBMA 2V75A 2NOBA 2NOEA 3OYIA 1KEAA 4BDYA 1KO9A 2H56A 4B23A 1KG2A 3CWSA 2XHIA 1XQOA 3I0XA 2JG6A 3R2XC 4E9EA 3OYMA 1PVSA 2NOLA 4AIAA 1HU0A 2NOFA 3L2VA 2YG9A 1XQPA 4YOQA 3OH6A 4DK9A 1M3QA 1DIZA 3VW4A 1FN7A 3KTUA 3CWAA 3OS2A 4HSBA 4EA4A 1PU8A 3OH9A 3OY9A 4EW4A 4ZTJA 3OGDA 3N0UA 1KG3A 3S3MA 4EA5A 1N39A 3NNQA 3OYKA 1WEFA 4B21A 3OYAA 4EW0A 3IHOA 1VRLA 1N3CA 1YQLA 2ABKA 3CW7A 1M3HA 4E9FA 2I5WA 1YQRA 3L2WA 2W04A 4EJYA 1LWYA 1XG7A 4E7LA 1MPGA 4UOBA 4YPHA 1MUNA 4YPRA 3N5NX 3L2RA 4B22A 4E7JA 1ORPA 5FRNA 4UNFA 3OYHA 3FHFA 1RRQA 1KQJA 4BACA 4OFHA 4NZGA 4AI5A 3OYCA 5KN8A 1KG5A 3FSPA 3S6IA 1PU7A 4EVVA 5AN4A 1KG6A 3L2UA 5CHZA 4E7HA 4E9HA 3OYNA 2JPSA 4OFEA 3I0WA 1P59A 2NOIA 5KN9A 1RRSA 3OYGA 5FRMA 3D4VA 4BE1A 4BE0A 1MUYA 3L2QA 1YQMA 3F0ZA 3S3NA 1YQKA 2NOZA 3OYLA 3CWUA 3CVSA 3OYJA 4E7KA 3CWTA 3OYFA 3OYEA 1NGNA 3CVTA 3KNTA 4EJZA 2NOHA 2YG8A 1LMZA 4BDZA 4OFAA
chains in the Genus database with same CATH topology
1PU6A 3G0QA 4B24A 2JHNA 1KG7A 1KG4A 1N3AA 1LWVA 1WEGA 1P7MA 1WEIA 2JHJA 1LWWA 3FHGA 3F10A 1NKUA 4AI4A 5DPKA 4PIIA 4E9GA 2OFKA 3IH7A 1MUDA 2OFIA 1ORNA 1EBMA 2NOEA 2NOBA 1KEAA 1KO9A 2H56A 4B23A 1KG2A 3CWSA 2XHIA 1XQOA 3I0XA 2JG6A 4E9EA 1PVSA 2NOLA 4AIAA 1HU0A 2NOFA 1M3QA 2YG9A 1XQPA 4YOQA 3OH6A 4DK9A 1DIZA 1FN7A 3KTUA 3CWAA 4HSBA 4EA4A 1PU8A 3OH9A 4EW4A 3OGDA 3N0UA 1KG3A 1N39A 4EA5A 1WEFA 4B21A 4EW0A 3IHOA 1VRLA 1N3CA 1YQLA 2ABKA 3CW7A 1M3HA 4E9FA 2I5WA 1YQRA 4EJYA 1LWYA 1XG7A 1MPGA 4UOBA 4YPHA 1MUNA 4YPRA 3N5NX 4B22A 1ORPA 4UNFA 3FHFA 1RRQA 1KQJA 4OFHA 4AI5A 3FSPA 5KN8A 1KG5A 3S6IA 1PU7A 4EVVA 5AN4A 1KG6A 5CHZA 4E9HA 4OFEA 3I0WA 1P59A 2NOIA 5KN9A 1RRSA 3D4VA 1MUYA 1YQMA 3F0ZA 1YQKA 2NOZA 3CWUA 3CVSA 3CWTA 1NGNA 3CVTA 3KNTA 4EJZA 2NOHA 2YG8A 1LMZA 4OFAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PU6 A;  3G0Q A;  4B24 A;  2JHN A;  1KG7 A;  1KG4 A;  1N3A A;  1LWV A;  1WEG A;  1P7M A;  1WEI A;  2JHJ A;  1LWW A;  3FHG A;  3F10 A;  1NKU A;  4AI4 A;  5DPK A;  4PII A;  4E9G A;  2OFK A;  3IH7 A;  1MUD A;  2OFI A;  1ORN A;  1EBM A;  2NOE A;  2NOB A;  1KEA A;  1KO9 A;  2H56 A;  4B23 A;  1KG2 A;  3CWS A;  2XHI A;  1XQO A;  3I0X A;  2JG6 A;  4E9E A;  1PVS A;  2NOL A;  4AIA A;  1HU0 A;  2NOF A;  1M3Q A;  2YG9 A;  1XQP A;  4YOQ A;  3OH6 A;  4DK9 A;  1DIZ A;  1FN7 A;  3KTU A;  3CWA A;  4HSB A;  4EA4 A;  1PU8 A;  3OH9 A;  4EW4 A;  3OGD A;  3N0U A;  1KG3 A;  1N39 A;  4EA5 A;  1WEF A;  4B21 A;  4EW0 A;  3IHO A;  1VRL A;  1N3C A;  1YQL A;  2ABK A;  3CW7 A;  1M3H A;  4E9F A;  2I5W A;  1YQR A;  4EJY A;  1LWY A;  1XG7 A;  1MPG A;  4UOB A;  4YPH A;  1MUN A;  4YPR A;  3N5N X;  4B22 A;  1ORP A;  4UNF A;  3FHF A;  1RRQ A;  1KQJ A;  4OFH A;  4AI5 A;  3FSP A;  5KN8 A;  1KG5 A;  3S6I A;  1PU7 A;  4EVV A;  5AN4 A;  1KG6 A;  5CHZ A;  4E9H A;  4OFE A;  3I0W A;  1P59 A;  2NOI A;  5KN9 A;  1RRS A;  3D4V A;  1MUY A;  1YQM A;  3F0Z A;  1YQK A;  2NOZ A;  3CWU A;  3CVS A;  3CWT A;  1NGN A;  3CVT A;  3KNT A;  4EJZ A;  2NOH A;  2YG8 A;  1LMZ A;  4OFA A; 
#chains in the Genus database with same CATH topology
 1PU6 A;  3G0Q A;  3OS1 A;  4B24 A;  2JHN A;  4ZTF A;  1KG7 A;  1KG4 A;  1N3A A;  1LWV A;  1WEG A;  4BE2 A;  1P7M A;  1WEI A;  2JHJ A;  1LWW A;  3FHG A;  2W03 A;  3OYB A;  4E7I A;  3F10 A;  1U84 A;  1NKU A;  5FRO A;  4AI4 A;  5DPK A;  4PII A;  3OYD A;  3LCN A;  4E9G A;  2OFK A;  3S3O A;  3IH7 A;  1MUD A;  2OFI A;  1ORN A;  3OS0 A;  4IKF A;  1EBM A;  2V75 A;  2NOB A;  2NOE A;  3OYI A;  1KEA A;  4BDY A;  1KO9 A;  2H56 A;  4B23 A;  1KG2 A;  3CWS A;  2XHI A;  1XQO A;  3I0X A;  2JG6 A;  3R2X C;  4E9E A;  3OYM A;  1PVS A;  2NOL A;  4AIA A;  1HU0 A;  2NOF A;  3L2V A;  2YG9 A;  1XQP A;  4YOQ A;  3OH6 A;  4DK9 A;  1M3Q A;  1DIZ A;  3VW4 A;  1FN7 A;  3KTU A;  3CWA A;  3OS2 A;  4HSB A;  4EA4 A;  1PU8 A;  3OH9 A;  3OY9 A;  4EW4 A;  4ZTJ A;  3OGD A;  3N0U A;  1KG3 A;  3S3M A;  4EA5 A;  1N39 A;  3NNQ A;  3OYK A;  1WEF A;  4B21 A;  3OYA A;  4EW0 A;  3IHO A;  1VRL A;  1N3C A;  1YQL A;  2ABK A;  3CW7 A;  1M3H A;  4E9F A;  2I5W A;  1YQR A;  3L2W A;  2W04 A;  4EJY A;  1LWY A;  1XG7 A;  4E7L A;  1MPG A;  4UOB A;  4YPH A;  1MUN A;  4YPR A;  3N5N X;  3L2R A;  4B22 A;  4E7J A;  1ORP A;  5FRN A;  4UNF A;  3OYH A;  3FHF A;  1RRQ A;  1KQJ A;  4BAC A;  4OFH A;  4NZG A;  4AI5 A;  3OYC A;  5KN8 A;  1KG5 A;  3FSP A;  3S6I A;  1PU7 A;  4EVV A;  5AN4 A;  1KG6 A;  3L2U A;  5CHZ A;  4E7H A;  4E9H A;  3OYN A;  2JPS A;  4OFE A;  3I0W A;  1P59 A;  2NOI A;  5KN9 A;  1RRS A;  3OYG A;  5FRM A;  3D4V A;  4BE1 A;  4BE0 A;  1MUY A;  3L2Q A;  1YQM A;  3F0Z A;  3S3N A;  1YQK A;  2NOZ A;  3OYL A;  3CWU A;  3CVS A;  3OYJ A;  4E7K A;  3CWT A;  3OYF A;  3OYE A;  1NGN A;  3CVT A;  3KNT A;  4EJZ A;  2NOH A;  2YG8 A;  1LMZ A;  4BDZ A;  4OFA A; 
#chains in the Genus database with same CATH homology
 1PU6 A;  3G0Q A;  4B24 A;  2JHN A;  1KG7 A;  1KG4 A;  1N3A A;  1LWV A;  1WEG A;  1P7M A;  1WEI A;  2JHJ A;  1LWW A;  3FHG A;  3F10 A;  1NKU A;  4AI4 A;  5DPK A;  4PII A;  4E9G A;  2OFK A;  3IH7 A;  1MUD A;  2OFI A;  1ORN A;  1EBM A;  2NOE A;  2NOB A;  1KEA A;  1KO9 A;  2H56 A;  4B23 A;  1KG2 A;  3CWS A;  2XHI A;  1XQO A;  3I0X A;  2JG6 A;  4E9E A;  1PVS A;  2NOL A;  4AIA A;  1HU0 A;  2NOF A;  1M3Q A;  2YG9 A;  1XQP A;  4YOQ A;  3OH6 A;  4DK9 A;  1DIZ A;  1FN7 A;  3KTU A;  3CWA A;  4HSB A;  4EA4 A;  1PU8 A;  3OH9 A;  4EW4 A;  3OGD A;  3N0U A;  1KG3 A;  1N39 A;  4EA5 A;  1WEF A;  4B21 A;  4EW0 A;  3IHO A;  1VRL A;  1N3C A;  1YQL A;  2ABK A;  3CW7 A;  1M3H A;  4E9F A;  2I5W A;  1YQR A;  4EJY A;  1LWY A;  1XG7 A;  1MPG A;  4UOB A;  4YPH A;  1MUN A;  4YPR A;  3N5N X;  4B22 A;  1ORP A;  4UNF A;  3FHF A;  1RRQ A;  1KQJ A;  4OFH A;  4AI5 A;  3FSP A;  5KN8 A;  1KG5 A;  3S6I A;  1PU7 A;  4EVV A;  5AN4 A;  1KG6 A;  5CHZ A;  4E9H A;  4OFE A;  3I0W A;  1P59 A;  2NOI A;  5KN9 A;  1RRS A;  3D4V A;  1MUY A;  1YQM A;  3F0Z A;  1YQK A;  2NOZ A;  3CWU A;  3CVS A;  3CWT A;  1NGN A;  3CVT A;  3KNT A;  4EJZ A;  2NOH A;  2YG8 A;  1LMZ A;  4OFA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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