1MUDA

Catalytic domain of muty from escherichia coli, d138n mutant complexed to adenine
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILNGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Adenine DNA glycosylase
publication title MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily.
pubmed doi rcsb
source organism Escherichia coli
total genus 71
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 1998-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1mudA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1mudA01
1ORNA 4B21A 1KG5A 4YPRA 3OH9A 3F10A 1XQPA 2OFIA 2YG8A 1LMZA 1PU6A 3S6IA 1NGNA 1MUNA 1KG7A 1P59A 2NOFA 4EJYA 1ORPA 1WEIA 2NOBA 4OFAA 1M3QA 3KNTA 1LWVA 4E9EA 4B23A 4YOQA 4OFHA 3CWTA 4HSBA 1YQMA 1KG2A 1M3HA 4EW0A 4EVVA 1WEGA 3OGDA 1HU0A 1KG4A 1YQRA 1LWYA 1DIZA 3CWUA 4PIIA 1KG6A 1LWWA 3D4VA 2NOLA 1NKUA 4E9GA 4EA4A 4E9HA 1YQLA 5DPKA 4B24A 3N5NX 3CVSA 1MUYA 2NOZA 1VRLA 3CW7A 4EJZA 4UNFA 2JHJA 3IH7A 4EW4A 1FN7A 3I0WA 4AIAA 4AI4A 2XHIA 3N0UA 3FHGA 4AI5A 5CHZA 1KQJA 5AN4A 1PVSA 3FHFA 2JG6A 2ABKA 1MPGA 4E9FA 1XG7A 1KO9A 2NOHA 3KTUA 1P7MA 2H56A 1YQKA 1WEFA 1N3CA 5KN8A 4DK9A 3IHOA 4OFEA 2OFKA 1EBMA 3CVTA 3OH6A 1RRQA 2YG9A 3CWSA 5KN9A 2NOEA 2JHNA 3G0QA 2NOIA 4UOBA 1PU8A 3F0ZA 3FSPA 1PU7A 1MUDA 4B22A 1KG3A 1RRSA 1XQOA 1N39A 4EA5A 3CWAA 3I0XA 2I5WA 1N3AA 1KEAA 4YPHA
chains in the Genus database with same CATH superfamily
1ORNA 4B21A 1KG5A 4BE1A 4YPRA 5FROA 3OS0A 3OH9A 3F10A 1XQPA 2OFIA 2YG8A 3OYIA 1LMZA 1PU6A 3S6IA 1NGNA 1MUNA 1KG7A 1P59A 2NOFA 3OYDA 1ORPA 4E7LA 4EJYA 1WEIA 3S3NA 2NOBA 3OYJA 4OFAA 4ZTFA 3L2VA 1M3QA 3OYHA 3KNTA 1LWVA 4BDZA 4E9EA 3OYBA 4B23A 4YOQA 4OFHA 4BACA 4IKFA 3CWTA 4HSBA 1YQMA 3L2QA 1KG2A 1U84A 1M3HA 4EW0A 4EVVA 1WEGA 3OGDA 1HU0A 1KG4A 1YQRA 1LWYA 1DIZA 3CWUA 4PIIA 1KG6A 1LWWA 3D4VA 2NOLA 1NKUA 4E9GA 4EA4A 4E9HA 3OYAA 1YQLA 3OYGA 4B24A 3N5NX 5DPKA 3OYCA 3CVSA 1MUYA 4BE2A 2NOZA 1VRLA 3CW7A 4EJZA 4NZGA 2V75A 4UNFA 3OS2A 3OS1A 4E7HA 2JHJA 3IH7A 4E7IA 4EW4A 1FN7A 3L2UA 3I0WA 4AIAA 4AI4A 2XHIA 3N0UA 4E7KA 3FHGA 4AI5A 5CHZA 3OYLA 3NNQA 3OYNA 5FRNA 5FRMA 1KQJA 5AN4A 1PVSA 3FHFA 2JG6A 2ABKA 1MPGA 3OYFA 4E9FA 1XG7A 1KO9A 2NOHA 3KTUA 3LCNA 4E7JA 1P7MA 2H56A 3S3MA 1YQKA 1WEFA 1N3CA 5KN8A 4BE0A 4DK9A 4ZTJA 3IHOA 4OFEA 2OFKA 3OYMA 1EBMA 3CVTA 3OH6A 1RRQA 4BDYA 2JPSA 2YG9A 3CWSA 5KN9A 3VW4A 3S3OA 2NOEA 2JHNA 3G0QA 2NOIA 4UOBA 1PU8A 3F0ZA 3FSPA 3L2WA 1PU7A 1MUDA 4B22A 1KG3A 3OY9A 1RRSA 1XQOA 2W04A 4EA5A 1N39A 3L2RA 3OYKA 3CWAA 2W03A 3R2XC 3I0XA 2I5WA 1N3AA 1KEAA 3OYEA 4YPHA
chains in the Genus database with same CATH topology
1ORNA 4B21A 1KG5A 4YPRA 3OH9A 3F10A 1XQPA 2OFIA 2YG8A 1LMZA 1PU6A 3S6IA 1NGNA 1MUNA 1KG7A 1P59A 2NOFA 4EJYA 1ORPA 1WEIA 2NOBA 4OFAA 1M3QA 3KNTA 1LWVA 4E9EA 4B23A 4YOQA 4OFHA 3CWTA 4HSBA 1YQMA 1KG2A 1M3HA 4EW0A 4EVVA 1WEGA 3OGDA 1HU0A 1KG4A 1YQRA 1LWYA 1DIZA 3CWUA 4PIIA 1KG6A 1LWWA 3D4VA 2NOLA 1NKUA 4E9GA 4EA4A 4E9HA 1YQLA 5DPKA 4B24A 3N5NX 3CVSA 1MUYA 2NOZA 1VRLA 3CW7A 4EJZA 4UNFA 2JHJA 3IH7A 4EW4A 1FN7A 3I0WA 4AIAA 4AI4A 2XHIA 3N0UA 3FHGA 4AI5A 5CHZA 1KQJA 5AN4A 1PVSA 3FHFA 2JG6A 2ABKA 1MPGA 4E9FA 1XG7A 1KO9A 2NOHA 3KTUA 1P7MA 2H56A 1YQKA 1WEFA 1N3CA 5KN8A 4DK9A 3IHOA 4OFEA 2OFKA 1EBMA 3CVTA 3OH6A 1RRQA 2YG9A 3CWSA 5KN9A 2NOEA 2JHNA 3G0QA 2NOIA 4UOBA 1PU8A 3F0ZA 3FSPA 1PU7A 1MUDA 4B22A 1KG3A 1RRSA 1XQOA 1N39A 4EA5A 3CWAA 3I0XA 2I5WA 1N3AA 1KEAA 4YPHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ORN A;  4B21 A;  1KG5 A;  4YPR A;  3OH9 A;  3F10 A;  1XQP A;  2OFI A;  2YG8 A;  1LMZ A;  1PU6 A;  3S6I A;  1NGN A;  1MUN A;  1KG7 A;  1P59 A;  2NOF A;  4EJY A;  1ORP A;  1WEI A;  2NOB A;  4OFA A;  1M3Q A;  3KNT A;  1LWV A;  4E9E A;  4B23 A;  4YOQ A;  4OFH A;  3CWT A;  4HSB A;  1YQM A;  1KG2 A;  1M3H A;  4EW0 A;  4EVV A;  1WEG A;  3OGD A;  1HU0 A;  1KG4 A;  1YQR A;  1LWY A;  1DIZ A;  3CWU A;  4PII A;  1KG6 A;  1LWW A;  3D4V A;  2NOL A;  1NKU A;  4E9G A;  4EA4 A;  4E9H A;  1YQL A;  5DPK A;  4B24 A;  3N5N X;  3CVS A;  1MUY A;  2NOZ A;  1VRL A;  3CW7 A;  4EJZ A;  4UNF A;  2JHJ A;  3IH7 A;  4EW4 A;  1FN7 A;  3I0W A;  4AIA A;  4AI4 A;  2XHI A;  3N0U A;  3FHG A;  4AI5 A;  5CHZ A;  1KQJ A;  5AN4 A;  1PVS A;  3FHF A;  2JG6 A;  2ABK A;  1MPG A;  4E9F A;  1XG7 A;  1KO9 A;  2NOH A;  3KTU A;  1P7M A;  2H56 A;  1YQK A;  1WEF A;  1N3C A;  5KN8 A;  4DK9 A;  3IHO A;  4OFE A;  2OFK A;  1EBM A;  3CVT A;  3OH6 A;  1RRQ A;  2YG9 A;  3CWS A;  5KN9 A;  2NOE A;  2JHN A;  3G0Q A;  2NOI A;  4UOB A;  1PU8 A;  3F0Z A;  3FSP A;  1PU7 A;  1MUD A;  4B22 A;  1KG3 A;  1RRS A;  1XQO A;  1N39 A;  4EA5 A;  3CWA A;  3I0X A;  2I5W A;  1N3A A;  1KEA A;  4YPH A; 
#chains in the Genus database with same CATH topology
 1ORN A;  4B21 A;  1KG5 A;  4BE1 A;  4YPR A;  5FRO A;  3OS0 A;  3OH9 A;  3F10 A;  1XQP A;  2OFI A;  2YG8 A;  3OYI A;  1LMZ A;  1PU6 A;  3S6I A;  1NGN A;  1MUN A;  1KG7 A;  1P59 A;  2NOF A;  3OYD A;  1ORP A;  4E7L A;  4EJY A;  1WEI A;  3S3N A;  2NOB A;  3OYJ A;  4OFA A;  4ZTF A;  3L2V A;  1M3Q A;  3OYH A;  3KNT A;  1LWV A;  4BDZ A;  4E9E A;  3OYB A;  4B23 A;  4YOQ A;  4OFH A;  4BAC A;  4IKF A;  3CWT A;  4HSB A;  1YQM A;  3L2Q A;  1KG2 A;  1U84 A;  1M3H A;  4EW0 A;  4EVV A;  1WEG A;  3OGD A;  1HU0 A;  1KG4 A;  1YQR A;  1LWY A;  1DIZ A;  3CWU A;  4PII A;  1KG6 A;  1LWW A;  3D4V A;  2NOL A;  1NKU A;  4E9G A;  4EA4 A;  4E9H A;  3OYA A;  1YQL A;  3OYG A;  4B24 A;  3N5N X;  5DPK A;  3OYC A;  3CVS A;  1MUY A;  4BE2 A;  2NOZ A;  1VRL A;  3CW7 A;  4EJZ A;  4NZG A;  2V75 A;  4UNF A;  3OS2 A;  3OS1 A;  4E7H A;  2JHJ A;  3IH7 A;  4E7I A;  4EW4 A;  1FN7 A;  3L2U A;  3I0W A;  4AIA A;  4AI4 A;  2XHI A;  3N0U A;  4E7K A;  3FHG A;  4AI5 A;  5CHZ A;  3OYL A;  3NNQ A;  3OYN A;  5FRN A;  5FRM A;  1KQJ A;  5AN4 A;  1PVS A;  3FHF A;  2JG6 A;  2ABK A;  1MPG A;  3OYF A;  4E9F A;  1XG7 A;  1KO9 A;  2NOH A;  3KTU A;  3LCN A;  4E7J A;  1P7M A;  2H56 A;  3S3M A;  1YQK A;  1WEF A;  1N3C A;  5KN8 A;  4BE0 A;  4DK9 A;  4ZTJ A;  3IHO A;  4OFE A;  2OFK A;  3OYM A;  1EBM A;  3CVT A;  3OH6 A;  1RRQ A;  4BDY A;  2JPS A;  2YG9 A;  3CWS A;  5KN9 A;  3VW4 A;  3S3O A;  2NOE A;  2JHN A;  3G0Q A;  2NOI A;  4UOB A;  1PU8 A;  3F0Z A;  3FSP A;  3L2W A;  1PU7 A;  1MUD A;  4B22 A;  1KG3 A;  3OY9 A;  1RRS A;  1XQO A;  2W04 A;  4EA5 A;  1N39 A;  3L2R A;  3OYK A;  3CWA A;  2W03 A;  3R2X C;  3I0X A;  2I5W A;  1N3A A;  1KEA A;  3OYE A;  4YPH A; 
#chains in the Genus database with same CATH homology
 1ORN A;  4B21 A;  1KG5 A;  4YPR A;  3OH9 A;  3F10 A;  1XQP A;  2OFI A;  2YG8 A;  1LMZ A;  1PU6 A;  3S6I A;  1NGN A;  1MUN A;  1KG7 A;  1P59 A;  2NOF A;  4EJY A;  1ORP A;  1WEI A;  2NOB A;  4OFA A;  1M3Q A;  3KNT A;  1LWV A;  4E9E A;  4B23 A;  4YOQ A;  4OFH A;  3CWT A;  4HSB A;  1YQM A;  1KG2 A;  1M3H A;  4EW0 A;  4EVV A;  1WEG A;  3OGD A;  1HU0 A;  1KG4 A;  1YQR A;  1LWY A;  1DIZ A;  3CWU A;  4PII A;  1KG6 A;  1LWW A;  3D4V A;  2NOL A;  1NKU A;  4E9G A;  4EA4 A;  4E9H A;  1YQL A;  5DPK A;  4B24 A;  3N5N X;  3CVS A;  1MUY A;  2NOZ A;  1VRL A;  3CW7 A;  4EJZ A;  4UNF A;  2JHJ A;  3IH7 A;  4EW4 A;  1FN7 A;  3I0W A;  4AIA A;  4AI4 A;  2XHI A;  3N0U A;  3FHG A;  4AI5 A;  5CHZ A;  1KQJ A;  5AN4 A;  1PVS A;  3FHF A;  2JG6 A;  2ABK A;  1MPG A;  4E9F A;  1XG7 A;  1KO9 A;  2NOH A;  3KTU A;  1P7M A;  2H56 A;  1YQK A;  1WEF A;  1N3C A;  5KN8 A;  4DK9 A;  3IHO A;  4OFE A;  2OFK A;  1EBM A;  3CVT A;  3OH6 A;  1RRQ A;  2YG9 A;  3CWS A;  5KN9 A;  2NOE A;  2JHN A;  3G0Q A;  2NOI A;  4UOB A;  1PU8 A;  3F0Z A;  3FSP A;  1PU7 A;  1MUD A;  4B22 A;  1KG3 A;  1RRS A;  1XQO A;  1N39 A;  4EA5 A;  3CWA A;  3I0X A;  2I5W A;  1N3A A;  1KEA A;  4YPH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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