1KG5A

Crystal structure of the k142q mutant of e.coli muty (core fragment)
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVQRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords A/G-specific adenine glycosylase
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
total genus 77
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg5A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg5A01
4AIAA 3CWUA 1PU6A 1LWVA 1N3AA 4EW4A 1NKUA 4E9FA 3G0QA 1WEGA 4EJYA 1MUYA 1P7MA 3CVSA 3CVTA 1N39A 3N5NX 4PIIA 1ORPA 3F0ZA 4E9HA 3N0UA 1HU0A 3CW7A 1FN7A 4OFEA 4E9GA 1KG7A 1WEIA 1KQJA 3I0WA 3OH9A 2OFIA 1LWYA 4EVVA 1N3CA 4E9EA 3CWTA 1LWWA 2NOZA 1PVSA 2XHIA 1XQOA 2NOEA 3CWAA 2JHJA 5AN4A 4YOQA 4EA5A 1YQRA 3S6IA 1KO9A 1P59A 4EJZA 1KG5A 2H56A 3CWSA 3FSPA 1KG2A 4B24A 1MPGA 4B22A 5KN9A 1KG6A 4OFHA 1XQPA 2YG9A 4EW0A 4YPRA 1KEAA 1KG4A 1WEFA 1EBMA 1YQKA 1M3HA 4B21A 1VRLA 1YQMA 2YG8A 1M3QA 1RRQA 3I0XA 4EA4A 3OGDA 1PU7A 1ORNA 3KNTA 4HSBA 2NOLA 3FHGA 1MUNA 4UNFA 2NOIA 2JHNA 2JG6A 1YQLA 1LMZA 1KG3A 1RRSA 1PU8A 2ABKA 5DPKA 1NGNA 3KTUA 4YPHA 5CHZA 2NOHA 4AI4A 3IHOA 1MUDA 4OFAA 3IH7A 4DK9A 4UOBA 1XG7A 2OFKA 5KN8A 3OH6A 4AI5A 1DIZA 2NOFA 4B23A 2I5WA 3F10A 3D4VA 3FHFA 2NOBA
chains in the Genus database with same CATH superfamily
4AIAA 3CWUA 3OY9A 4IKFA 1PU6A 1LWVA 1N3AA 4BDZA 4EW4A 1NKUA 3OYIA 4E9FA 3S3OA 3G0QA 1WEGA 4EJYA 1MUYA 1P7MA 3R2XC 3OYFA 3CVSA 3CVTA 1N39A 3N5NX 4PIIA 3OYHA 1ORPA 3F0ZA 4E9HA 3N0UA 4NZGA 1HU0A 3CW7A 3OS2A 4BE2A 1FN7A 4OFEA 4E9GA 1KG7A 1WEIA 1KQJA 3OYGA 3OYAA 3L2WA 3OYJA 3I0WA 4E7HA 3OH9A 2OFIA 1LWYA 4EVVA 3OYLA 1N3CA 4E9EA 3CWTA 4BE1A 1U84A 1LWWA 2NOZA 1PVSA 2W03A 2XHIA 1XQOA 4E7LA 3VW4A 2NOEA 3S3MA 3CWAA 2JHJA 5AN4A 5FROA 4YOQA 4EA5A 1YQRA 3S6IA 2V75A 4BACA 3OYKA 1KO9A 1P59A 3L2UA 3OYBA 3OYMA 4EJZA 1KG5A 2H56A 3CWSA 3FSPA 1KG2A 4B24A 1MPGA 4B22A 4BDYA 5KN9A 1KG6A 4OFHA 1XQPA 2YG9A 4EW0A 4YPRA 5FRNA 1KEAA 1KG4A 1WEFA 1EBMA 3OYDA 2JPSA 1YQKA 5FRMA 4E7KA 3NNQA 1M3HA 4B21A 1VRLA 3OS0A 4E7JA 1YQMA 2YG8A 1M3QA 1RRQA 3I0XA 4EA4A 3OGDA 1PU7A 1ORNA 3KNTA 4ZTFA 4HSBA 2NOLA 3L2RA 3FHGA 1MUNA 4UNFA 2NOIA 2JHNA 2JG6A 1YQLA 1LMZA 1KG3A 1RRSA 1PU8A 2ABKA 5DPKA 3L2QA 1NGNA 3OYNA 3KTUA 2W04A 4YPHA 5CHZA 2NOHA 4AI4A 3LCNA 3IHOA 1MUDA 4OFAA 3IH7A 4DK9A 3OYEA 4UOBA 3L2VA 1XG7A 2OFKA 5KN8A 3OH6A 3OYCA 4ZTJA 4AI5A 1DIZA 2NOFA 3OS1A 4B23A 2I5WA 3F10A 4BE0A 3D4VA 3FHFA 2NOBA 3S3NA 4E7IA
chains in the Genus database with same CATH topology
4AIAA 3CWUA 1PU6A 1LWVA 1N3AA 4EW4A 1NKUA 4E9FA 3G0QA 1WEGA 4EJYA 1MUYA 1P7MA 3CVSA 3CVTA 1N39A 3N5NX 4PIIA 1ORPA 3F0ZA 4E9HA 3N0UA 1HU0A 3CW7A 1FN7A 4OFEA 4E9GA 1KG7A 1WEIA 1KQJA 3I0WA 3OH9A 2OFIA 1LWYA 4EVVA 1N3CA 4E9EA 3CWTA 1LWWA 2NOZA 1PVSA 2XHIA 1XQOA 2NOEA 3CWAA 2JHJA 5AN4A 4YOQA 4EA5A 1YQRA 3S6IA 1KO9A 1P59A 4EJZA 1KG5A 2H56A 3CWSA 3FSPA 1KG2A 4B24A 1MPGA 4B22A 5KN9A 1KG6A 4OFHA 1XQPA 2YG9A 4EW0A 4YPRA 1KEAA 1KG4A 1WEFA 1EBMA 1YQKA 1M3HA 4B21A 1VRLA 1YQMA 2YG8A 1M3QA 1RRQA 3I0XA 4EA4A 3OGDA 1PU7A 1ORNA 3KNTA 4HSBA 2NOLA 3FHGA 1MUNA 4UNFA 2NOIA 2JHNA 2JG6A 1YQLA 1LMZA 1KG3A 1RRSA 1PU8A 2ABKA 5DPKA 1NGNA 3KTUA 4YPHA 5CHZA 2NOHA 4AI4A 3IHOA 1MUDA 4OFAA 3IH7A 4DK9A 4UOBA 1XG7A 2OFKA 5KN8A 3OH6A 4AI5A 1DIZA 2NOFA 4B23A 2I5WA 3F10A 3D4VA 3FHFA 2NOBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AIA A;  3CWU A;  1PU6 A;  1LWV A;  1N3A A;  4EW4 A;  1NKU A;  4E9F A;  3G0Q A;  1WEG A;  4EJY A;  1MUY A;  1P7M A;  3CVS A;  3CVT A;  1N39 A;  3N5N X;  4PII A;  1ORP A;  3F0Z A;  4E9H A;  3N0U A;  1HU0 A;  3CW7 A;  1FN7 A;  4OFE A;  4E9G A;  1KG7 A;  1WEI A;  1KQJ A;  3I0W A;  3OH9 A;  2OFI A;  1LWY A;  4EVV A;  1N3C A;  4E9E A;  3CWT A;  1LWW A;  2NOZ A;  1PVS A;  2XHI A;  1XQO A;  2NOE A;  3CWA A;  2JHJ A;  5AN4 A;  4YOQ A;  4EA5 A;  1YQR A;  3S6I A;  1KO9 A;  1P59 A;  4EJZ A;  1KG5 A;  2H56 A;  3CWS A;  3FSP A;  1KG2 A;  4B24 A;  1MPG A;  4B22 A;  5KN9 A;  1KG6 A;  4OFH A;  1XQP A;  2YG9 A;  4EW0 A;  4YPR A;  1KEA A;  1KG4 A;  1WEF A;  1EBM A;  1YQK A;  1M3H A;  4B21 A;  1VRL A;  1YQM A;  2YG8 A;  1M3Q A;  1RRQ A;  3I0X A;  4EA4 A;  3OGD A;  1PU7 A;  1ORN A;  3KNT A;  4HSB A;  2NOL A;  3FHG A;  1MUN A;  4UNF A;  2NOI A;  2JHN A;  2JG6 A;  1YQL A;  1LMZ A;  1KG3 A;  1RRS A;  1PU8 A;  2ABK A;  5DPK A;  1NGN A;  3KTU A;  4YPH A;  5CHZ A;  2NOH A;  4AI4 A;  3IHO A;  1MUD A;  4OFA A;  3IH7 A;  4DK9 A;  4UOB A;  1XG7 A;  2OFK A;  5KN8 A;  3OH6 A;  4AI5 A;  1DIZ A;  2NOF A;  4B23 A;  2I5W A;  3F10 A;  3D4V A;  3FHF A;  2NOB A; 
#chains in the Genus database with same CATH topology
 4AIA A;  3CWU A;  3OY9 A;  4IKF A;  1PU6 A;  1LWV A;  1N3A A;  4BDZ A;  4EW4 A;  1NKU A;  3OYI A;  4E9F A;  3S3O A;  3G0Q A;  1WEG A;  4EJY A;  1MUY A;  1P7M A;  3R2X C;  3OYF A;  3CVS A;  3CVT A;  1N39 A;  3N5N X;  4PII A;  3OYH A;  1ORP A;  3F0Z A;  4E9H A;  3N0U A;  4NZG A;  1HU0 A;  3CW7 A;  3OS2 A;  4BE2 A;  1FN7 A;  4OFE A;  4E9G A;  1KG7 A;  1WEI A;  1KQJ A;  3OYG A;  3OYA A;  3L2W A;  3OYJ A;  3I0W A;  4E7H A;  3OH9 A;  2OFI A;  1LWY A;  4EVV A;  3OYL A;  1N3C A;  4E9E A;  3CWT A;  4BE1 A;  1U84 A;  1LWW A;  2NOZ A;  1PVS A;  2W03 A;  2XHI A;  1XQO A;  4E7L A;  3VW4 A;  2NOE A;  3S3M A;  3CWA A;  2JHJ A;  5AN4 A;  5FRO A;  4YOQ A;  4EA5 A;  1YQR A;  3S6I A;  2V75 A;  4BAC A;  3OYK A;  1KO9 A;  1P59 A;  3L2U A;  3OYB A;  3OYM A;  4EJZ A;  1KG5 A;  2H56 A;  3CWS A;  3FSP A;  1KG2 A;  4B24 A;  1MPG A;  4B22 A;  4BDY A;  5KN9 A;  1KG6 A;  4OFH A;  1XQP A;  2YG9 A;  4EW0 A;  4YPR A;  5FRN A;  1KEA A;  1KG4 A;  1WEF A;  1EBM A;  3OYD A;  2JPS A;  1YQK A;  5FRM A;  4E7K A;  3NNQ A;  1M3H A;  4B21 A;  1VRL A;  3OS0 A;  4E7J A;  1YQM A;  2YG8 A;  1M3Q A;  1RRQ A;  3I0X A;  4EA4 A;  3OGD A;  1PU7 A;  1ORN A;  3KNT A;  4ZTF A;  4HSB A;  2NOL A;  3L2R A;  3FHG A;  1MUN A;  4UNF A;  2NOI A;  2JHN A;  2JG6 A;  1YQL A;  1LMZ A;  1KG3 A;  1RRS A;  1PU8 A;  2ABK A;  5DPK A;  3L2Q A;  1NGN A;  3OYN A;  3KTU A;  2W04 A;  4YPH A;  5CHZ A;  2NOH A;  4AI4 A;  3LCN A;  3IHO A;  1MUD A;  4OFA A;  3IH7 A;  4DK9 A;  3OYE A;  4UOB A;  3L2V A;  1XG7 A;  2OFK A;  5KN8 A;  3OH6 A;  3OYC A;  4ZTJ A;  4AI5 A;  1DIZ A;  2NOF A;  3OS1 A;  4B23 A;  2I5W A;  3F10 A;  4BE0 A;  3D4V A;  3FHF A;  2NOB A;  3S3N A;  4E7I A; 
#chains in the Genus database with same CATH homology
 4AIA A;  3CWU A;  1PU6 A;  1LWV A;  1N3A A;  4EW4 A;  1NKU A;  4E9F A;  3G0Q A;  1WEG A;  4EJY A;  1MUY A;  1P7M A;  3CVS A;  3CVT A;  1N39 A;  3N5N X;  4PII A;  1ORP A;  3F0Z A;  4E9H A;  3N0U A;  1HU0 A;  3CW7 A;  1FN7 A;  4OFE A;  4E9G A;  1KG7 A;  1WEI A;  1KQJ A;  3I0W A;  3OH9 A;  2OFI A;  1LWY A;  4EVV A;  1N3C A;  4E9E A;  3CWT A;  1LWW A;  2NOZ A;  1PVS A;  2XHI A;  1XQO A;  2NOE A;  3CWA A;  2JHJ A;  5AN4 A;  4YOQ A;  4EA5 A;  1YQR A;  3S6I A;  1KO9 A;  1P59 A;  4EJZ A;  1KG5 A;  2H56 A;  3CWS A;  3FSP A;  1KG2 A;  4B24 A;  1MPG A;  4B22 A;  5KN9 A;  1KG6 A;  4OFH A;  1XQP A;  2YG9 A;  4EW0 A;  4YPR A;  1KEA A;  1KG4 A;  1WEF A;  1EBM A;  1YQK A;  1M3H A;  4B21 A;  1VRL A;  1YQM A;  2YG8 A;  1M3Q A;  1RRQ A;  3I0X A;  4EA4 A;  3OGD A;  1PU7 A;  1ORN A;  3KNT A;  4HSB A;  2NOL A;  3FHG A;  1MUN A;  4UNF A;  2NOI A;  2JHN A;  2JG6 A;  1YQL A;  1LMZ A;  1KG3 A;  1RRS A;  1PU8 A;  2ABK A;  5DPK A;  1NGN A;  3KTU A;  4YPH A;  5CHZ A;  2NOH A;  4AI4 A;  3IHO A;  1MUD A;  4OFA A;  3IH7 A;  4DK9 A;  4UOB A;  1XG7 A;  2OFK A;  5KN8 A;  3OH6 A;  4AI5 A;  1DIZ A;  2NOF A;  4B23 A;  2I5W A;  3F10 A;  3D4V A;  3FHF A;  2NOB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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