1KG5A

Crystal structure of the k142q mutant of e.coli muty (core fragment)
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVQRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 77
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg5A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg5A01
1ORPA 3CVTA 5KN9A 1YQKA 3KTUA 1P59A 2NOBA 5KN8A 4OFEA 3D4VA 3S6IA 3CWAA 5CHZA 4E9GA 4EA5A 4EW0A 1LMZA 4DK9A 3CWSA 1MUNA 2ABKA 3F10A 3FHFA 4AI5A 3IHOA 5AN4A 1YQRA 1N3AA 1PU6A 1YQMA 1EBMA 1XQOA 3KNTA 2NOZA 3OH6A 3CWTA 1MUYA 2NOFA 1P7MA 3I0XA 4HSBA 3FSPA 4YPHA 4B23A 1KG2A 1NGNA 4UOBA 4EJZA 1PU8A 3CW7A 2NOLA 3CVSA 4AIAA 2I5WA 1KG6A 2JHJA 3FHGA 1M3HA 4B22A 4YPRA 4UNFA 1XQPA 2YG9A 3OH9A 1N3CA 1LWYA 2JG6A 4E9EA 3N5NX 2NOHA 1WEGA 1XG7A 1KEAA 1WEFA 1LWWA 1DIZA 1MPGA 1MUDA 1KG7A 3OGDA 4E9HA 3CWUA 3I0WA 1WEIA 3IH7A 2YG8A 1KG4A 5DPKA 1PVSA 1M3QA 2OFIA 4PIIA 1KO9A 1FN7A 2NOIA 1HU0A 4E9FA 2JHNA 2XHIA 4B24A 1YQLA 1RRSA 1KQJA 2NOEA 4EJYA 1RRQA 4EVVA 3N0UA 1PU7A 3G0QA 1VRLA 4OFAA 1KG3A 1N39A 3F0ZA 4AI4A 2OFKA 1LWVA 4YOQA 4EA4A 1KG5A 1NKUA 4OFHA 2H56A 4EW4A 4B21A 1ORNA
chains in the Genus database with same CATH superfamily
1ORPA 3CVTA 5KN9A 3S3MA 1YQKA 3KTUA 1P59A 2NOBA 3S3OA 5KN8A 4OFEA 3D4VA 3S6IA 3CWAA 5CHZA 3NNQA 4E9GA 4EA5A 4EW0A 1LMZA 3OYLA 4NZGA 4DK9A 3OYKA 4E7IA 3CWSA 1MUNA 2ABKA 3OYFA 2V75A 3F10A 3OS2A 4BDYA 3FHFA 4AI5A 4BE0A 3IHOA 5AN4A 3LCNA 1YQRA 1N3AA 3OS0A 1PU6A 1YQMA 1EBMA 1XQOA 4BACA 3KNTA 2NOZA 3OYCA 3OH6A 3CWTA 1MUYA 2NOFA 1P7MA 3I0XA 4HSBA 3FSPA 4YPHA 4B23A 1KG2A 1NGNA 4UOBA 2W04A 4EJZA 1PU8A 3CW7A 2NOLA 3CVSA 1U84A 4AIAA 2I5WA 1KG6A 2JHJA 3FHGA 1M3HA 4B22A 3L2UA 4E7HA 3VW4A 4YPRA 4E7LA 4UNFA 1XQPA 4BDZA 2YG9A 3OH9A 1N3CA 1LWYA 2JG6A 4E9EA 3OS1A 5FROA 3N5NX 4E7KA 2NOHA 1WEGA 1XG7A 1KEAA 5FRNA 1WEFA 3OYHA 1LWWA 1DIZA 1MPGA 1MUDA 1KG7A 2W03A 3OGDA 4E9HA 3OY9A 3OYMA 3CWUA 3I0WA 3OYAA 3OYJA 1WEIA 3IH7A 3OYDA 2YG8A 3L2VA 1KG4A 3OYNA 5DPKA 1PVSA 1M3QA 2OFIA 4PIIA 4IKFA 1KO9A 1FN7A 2NOIA 1HU0A 4BE1A 4E9FA 2JHNA 2XHIA 3L2QA 4B24A 4E7JA 1YQLA 1RRSA 1KQJA 3L2RA 2NOEA 4EJYA 1RRQA 5FRMA 4EVVA 3N0UA 1PU7A 3OYEA 3G0QA 4BE2A 4OFAA 1VRLA 3R2XC 2JPSA 1KG3A 1N39A 3F0ZA 3L2WA 4AI4A 2OFKA 3OYIA 4ZTFA 1LWVA 4YOQA 4EA4A 1KG5A 1NKUA 4OFHA 3OYGA 2H56A 4EW4A 4B21A 1ORNA 3OYBA 3S3NA 4ZTJA
chains in the Genus database with same CATH topology
1ORPA 3CVTA 5KN9A 1YQKA 3KTUA 1P59A 2NOBA 5KN8A 4OFEA 3D4VA 3S6IA 3CWAA 5CHZA 4E9GA 4EA5A 4EW0A 1LMZA 4DK9A 3CWSA 1MUNA 2ABKA 3F10A 3FHFA 4AI5A 3IHOA 5AN4A 1YQRA 1N3AA 1PU6A 1YQMA 1EBMA 1XQOA 3KNTA 2NOZA 3OH6A 3CWTA 1MUYA 2NOFA 1P7MA 3I0XA 4HSBA 3FSPA 4YPHA 4B23A 1KG2A 1NGNA 4UOBA 4EJZA 1PU8A 3CW7A 2NOLA 3CVSA 4AIAA 2I5WA 1KG6A 2JHJA 3FHGA 1M3HA 4B22A 4YPRA 4UNFA 1XQPA 2YG9A 3OH9A 1N3CA 1LWYA 2JG6A 4E9EA 3N5NX 2NOHA 1WEGA 1XG7A 1KEAA 1WEFA 1LWWA 1DIZA 1MPGA 1MUDA 1KG7A 3OGDA 4E9HA 3CWUA 3I0WA 1WEIA 3IH7A 2YG8A 1KG4A 5DPKA 1PVSA 1M3QA 2OFIA 4PIIA 1KO9A 1FN7A 2NOIA 1HU0A 4E9FA 2JHNA 2XHIA 4B24A 1YQLA 1RRSA 1KQJA 2NOEA 4EJYA 1RRQA 4EVVA 3N0UA 1PU7A 3G0QA 1VRLA 4OFAA 1KG3A 1N39A 3F0ZA 4AI4A 2OFKA 1LWVA 4YOQA 4EA4A 1KG5A 1NKUA 4OFHA 2H56A 4EW4A 4B21A 1ORNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ORP A;  3CVT A;  5KN9 A;  1YQK A;  3KTU A;  1P59 A;  2NOB A;  5KN8 A;  4OFE A;  3D4V A;  3S6I A;  3CWA A;  5CHZ A;  4E9G A;  4EA5 A;  4EW0 A;  1LMZ A;  4DK9 A;  3CWS A;  1MUN A;  2ABK A;  3F10 A;  3FHF A;  4AI5 A;  3IHO A;  5AN4 A;  1YQR A;  1N3A A;  1PU6 A;  1YQM A;  1EBM A;  1XQO A;  3KNT A;  2NOZ A;  3OH6 A;  3CWT A;  1MUY A;  2NOF A;  1P7M A;  3I0X A;  4HSB A;  3FSP A;  4YPH A;  4B23 A;  1KG2 A;  1NGN A;  4UOB A;  4EJZ A;  1PU8 A;  3CW7 A;  2NOL A;  3CVS A;  4AIA A;  2I5W A;  1KG6 A;  2JHJ A;  3FHG A;  1M3H A;  4B22 A;  4YPR A;  4UNF A;  1XQP A;  2YG9 A;  3OH9 A;  1N3C A;  1LWY A;  2JG6 A;  4E9E A;  3N5N X;  2NOH A;  1WEG A;  1XG7 A;  1KEA A;  1WEF A;  1LWW A;  1DIZ A;  1MPG A;  1MUD A;  1KG7 A;  3OGD A;  4E9H A;  3CWU A;  3I0W A;  1WEI A;  3IH7 A;  2YG8 A;  1KG4 A;  5DPK A;  1PVS A;  1M3Q A;  2OFI A;  4PII A;  1KO9 A;  1FN7 A;  2NOI A;  1HU0 A;  4E9F A;  2JHN A;  2XHI A;  4B24 A;  1YQL A;  1RRS A;  1KQJ A;  2NOE A;  4EJY A;  1RRQ A;  4EVV A;  3N0U A;  1PU7 A;  3G0Q A;  1VRL A;  4OFA A;  1KG3 A;  1N39 A;  3F0Z A;  4AI4 A;  2OFK A;  1LWV A;  4YOQ A;  4EA4 A;  1KG5 A;  1NKU A;  4OFH A;  2H56 A;  4EW4 A;  4B21 A;  1ORN A; 
#chains in the Genus database with same CATH topology
 1ORP A;  3CVT A;  5KN9 A;  3S3M A;  1YQK A;  3KTU A;  1P59 A;  2NOB A;  3S3O A;  5KN8 A;  4OFE A;  3D4V A;  3S6I A;  3CWA A;  5CHZ A;  3NNQ A;  4E9G A;  4EA5 A;  4EW0 A;  1LMZ A;  3OYL A;  4NZG A;  4DK9 A;  3OYK A;  4E7I A;  3CWS A;  1MUN A;  2ABK A;  3OYF A;  2V75 A;  3F10 A;  3OS2 A;  4BDY A;  3FHF A;  4AI5 A;  4BE0 A;  3IHO A;  5AN4 A;  3LCN A;  1YQR A;  1N3A A;  3OS0 A;  1PU6 A;  1YQM A;  1EBM A;  1XQO A;  4BAC A;  3KNT A;  2NOZ A;  3OYC A;  3OH6 A;  3CWT A;  1MUY A;  2NOF A;  1P7M A;  3I0X A;  4HSB A;  3FSP A;  4YPH A;  4B23 A;  1KG2 A;  1NGN A;  4UOB A;  2W04 A;  4EJZ A;  1PU8 A;  3CW7 A;  2NOL A;  3CVS A;  1U84 A;  4AIA A;  2I5W A;  1KG6 A;  2JHJ A;  3FHG A;  1M3H A;  4B22 A;  3L2U A;  4E7H A;  3VW4 A;  4YPR A;  4E7L A;  4UNF A;  1XQP A;  4BDZ A;  2YG9 A;  3OH9 A;  1N3C A;  1LWY A;  2JG6 A;  4E9E A;  3OS1 A;  5FRO A;  3N5N X;  4E7K A;  2NOH A;  1WEG A;  1XG7 A;  1KEA A;  5FRN A;  1WEF A;  3OYH A;  1LWW A;  1DIZ A;  1MPG A;  1MUD A;  1KG7 A;  2W03 A;  3OGD A;  4E9H A;  3OY9 A;  3OYM A;  3CWU A;  3I0W A;  3OYA A;  3OYJ A;  1WEI A;  3IH7 A;  3OYD A;  2YG8 A;  3L2V A;  1KG4 A;  3OYN A;  5DPK A;  1PVS A;  1M3Q A;  2OFI A;  4PII A;  4IKF A;  1KO9 A;  1FN7 A;  2NOI A;  1HU0 A;  4BE1 A;  4E9F A;  2JHN A;  2XHI A;  3L2Q A;  4B24 A;  4E7J A;  1YQL A;  1RRS A;  1KQJ A;  3L2R A;  2NOE A;  4EJY A;  1RRQ A;  5FRM A;  4EVV A;  3N0U A;  1PU7 A;  3OYE A;  3G0Q A;  4BE2 A;  4OFA A;  1VRL A;  3R2X C;  2JPS A;  1KG3 A;  1N39 A;  3F0Z A;  3L2W A;  4AI4 A;  2OFK A;  3OYI A;  4ZTF A;  1LWV A;  4YOQ A;  4EA4 A;  1KG5 A;  1NKU A;  4OFH A;  3OYG A;  2H56 A;  4EW4 A;  4B21 A;  1ORN A;  3OYB A;  3S3N A;  4ZTJ A; 
#chains in the Genus database with same CATH homology
 1ORP A;  3CVT A;  5KN9 A;  1YQK A;  3KTU A;  1P59 A;  2NOB A;  5KN8 A;  4OFE A;  3D4V A;  3S6I A;  3CWA A;  5CHZ A;  4E9G A;  4EA5 A;  4EW0 A;  1LMZ A;  4DK9 A;  3CWS A;  1MUN A;  2ABK A;  3F10 A;  3FHF A;  4AI5 A;  3IHO A;  5AN4 A;  1YQR A;  1N3A A;  1PU6 A;  1YQM A;  1EBM A;  1XQO A;  3KNT A;  2NOZ A;  3OH6 A;  3CWT A;  1MUY A;  2NOF A;  1P7M A;  3I0X A;  4HSB A;  3FSP A;  4YPH A;  4B23 A;  1KG2 A;  1NGN A;  4UOB A;  4EJZ A;  1PU8 A;  3CW7 A;  2NOL A;  3CVS A;  4AIA A;  2I5W A;  1KG6 A;  2JHJ A;  3FHG A;  1M3H A;  4B22 A;  4YPR A;  4UNF A;  1XQP A;  2YG9 A;  3OH9 A;  1N3C A;  1LWY A;  2JG6 A;  4E9E A;  3N5N X;  2NOH A;  1WEG A;  1XG7 A;  1KEA A;  1WEF A;  1LWW A;  1DIZ A;  1MPG A;  1MUD A;  1KG7 A;  3OGD A;  4E9H A;  3CWU A;  3I0W A;  1WEI A;  3IH7 A;  2YG8 A;  1KG4 A;  5DPK A;  1PVS A;  1M3Q A;  2OFI A;  4PII A;  1KO9 A;  1FN7 A;  2NOI A;  1HU0 A;  4E9F A;  2JHN A;  2XHI A;  4B24 A;  1YQL A;  1RRS A;  1KQJ A;  2NOE A;  4EJY A;  1RRQ A;  4EVV A;  3N0U A;  1PU7 A;  3G0Q A;  1VRL A;  4OFA A;  1KG3 A;  1N39 A;  3F0Z A;  4AI4 A;  2OFK A;  1LWV A;  4YOQ A;  4EA4 A;  1KG5 A;  1NKU A;  4OFH A;  2H56 A;  4EW4 A;  4B21 A;  1ORN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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