1XQPA

Crystal structure of 8-oxoguanosine complexed pa-agog, 8-oxoguanine dna glycosylase from pyrobaculum aerophilum
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
252
structure length
252
Chain Sequence
AESQLKRVIETLRRLGIEEVLKLERRDPQYRAVCNVVKRHGETVGSRLAMLNALISYRLTGKGEEHWEYFGKYFSQLEVIDLCRDFLKYIETSPFLKIGVEARKKRALKACDYVPNLEDLGLTLRQLSHIVGARREQKTLVFTIKILNYAYMCSRGVNRVLPFDIPIPVDYRVARLTWCAGLIDFPPEEALRRYEAVQKIWDAVARETGIPPLHLDTLLWLAGRAVLYGENLHGVPKEVIALFQWRGGCRPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 8-oxoguanine DNA glycosylase
publication title A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
pubmed doi rcsb
source organism Pyrobaculum aerophilum
molecule tags Lyase
total genus 95
structure length 252
sequence length 252
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09171 AGOG N-glycosylase/DNA lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1xqpA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1xqpA01
1MUYA 1YQMA 2YG8A 1PU7A 1YQLA 2YG9A 3G0QA 5CHZA 1DIZA 4EA4A 1VRLA 4B22A 1MPGA 5DPKA 4YPHA 3IHOA 3S6IA 1WEFA 1WEIA 3FHGA 4AIAA 1ORPA 4EJZA 2NOBA 4EW0A 1HU0A 5AN4A 3I0WA 3CVSA 1MUNA 2JHNA 2JG6A 1WEGA 2NOFA 1M3HA 3CWTA 2XHIA 4EA5A 2NOZA 1KG3A 4YPRA 1N39A 1KQJA 1LMZA 3FHFA 1NKUA 4B21A 2NOHA 4UNFA 1N3CA 1YQKA 3OH6A 4DK9A 4AI5A 4YOQA 4UOBA 1M3QA 2NOLA 2NOIA 3I0XA 1KG5A 3F0ZA 4EVVA 3IH7A 1ORNA 4E9HA 1EBMA 1XG7A 3OH9A 4OFEA 4EW4A 1KEAA 5KN9A 1KG2A 3OGDA 1RRSA 1PU6A 3KTUA 1KO9A 2I5WA 2OFKA 3F10A 1KG4A 1P7MA 3CWUA 2JHJA 3FSPA 4EJYA 4E9GA 2H56A 1FN7A 1RRQA 4E9EA 1YQRA 2OFIA 2ABKA 1NGNA 1XQPA 4E9FA 1LWVA 5KN8A 3N0UA 1KG7A 4OFAA 1KG6A 1P59A 4B23A 1XQOA 1MUDA 1N3AA 3CWSA 2NOEA 3KNTA 1PVSA 3CVTA 4PIIA 1LWWA 1PU8A 3N5NX 4HSBA 1LWYA 4OFHA 4B24A 3CWAA 3CW7A 4AI4A 3D4VA
chains in the Genus database with same CATH superfamily
1MUYA 1YQMA 2YG8A 1PU7A 1YQLA 3LCNA 2YG9A 3G0QA 5CHZA 5FRNA 4E7HA 3OYNA 4BE2A 1DIZA 3L2UA 4EA4A 1VRLA 4B22A 1MPGA 4E7KA 5DPKA 4YPHA 3IHOA 3S6IA 1WEFA 1WEIA 3FHGA 4AIAA 1ORPA 4EJZA 2NOBA 4EW0A 3L2VA 1HU0A 3R2XC 5AN4A 3S3NA 3S3MA 3I0WA 3L2WA 4E7IA 3CVSA 1MUNA 4BE1A 2JHNA 2JG6A 3L2RA 1U84A 1WEGA 4NZGA 4E7JA 4ZTJA 2NOFA 4BE0A 1M3HA 3OYDA 2XHIA 4EA5A 3CWTA 2NOZA 1KG3A 2JPSA 4YPRA 1N39A 2W04A 1KQJA 1LMZA 3FHFA 1NKUA 3OY9A 4B21A 2NOHA 4UNFA 1N3CA 1YQKA 3OYIA 4BDYA 3OH6A 3NNQA 4DK9A 4AI5A 4YOQA 4UOBA 1M3QA 5FRMA 2NOLA 3OYLA 2NOIA 3I0XA 1KG5A 3F0ZA 4EVVA 3IH7A 1ORNA 2W03A 4E9HA 1EBMA 1XG7A 3OH9A 4OFEA 4EW4A 1KEAA 5KN9A 3OS2A 3OYMA 1KG2A 3OGDA 1RRSA 1PU6A 3OYHA 3KTUA 1KO9A 3OYEA 2I5WA 2OFKA 3F10A 1KG4A 1P7MA 3CWUA 4BDZA 2JHJA 4E7LA 3FSPA 4EJYA 4E9GA 2H56A 3OYKA 1FN7A 1RRQA 4E9EA 1YQRA 2OFIA 2ABKA 1NGNA 1XQPA 5FROA 4E9FA 1LWVA 5KN8A 3N0UA 3S3OA 3L2QA 1KG7A 4OFAA 3OYFA 1KG6A 2V75A 3OS0A 1P59A 4IKFA 4B23A 1XQOA 1MUDA 1N3AA 3CWSA 3VW4A 2NOEA 3OS1A 3KNTA 4BACA 4ZTFA 1PVSA 3OYCA 3OYGA 3OYBA 3OYAA 3CVTA 3OYJA 4PIIA 1LWWA 1PU8A 3N5NX 4HSBA 1LWYA 4OFHA 4B24A 3CWAA 3CW7A 4AI4A 3D4VA
chains in the Genus database with same CATH topology
1MUYA 1YQMA 2YG8A 1PU7A 1YQLA 2YG9A 3G0QA 5CHZA 1DIZA 4EA4A 1VRLA 4B22A 1MPGA 5DPKA 4YPHA 3IHOA 3S6IA 1WEFA 1WEIA 3FHGA 4AIAA 1ORPA 4EJZA 2NOBA 4EW0A 1HU0A 5AN4A 3I0WA 3CVSA 1MUNA 2JHNA 2JG6A 1WEGA 2NOFA 1M3HA 3CWTA 2XHIA 4EA5A 2NOZA 1KG3A 4YPRA 1N39A 1KQJA 1LMZA 3FHFA 1NKUA 4B21A 2NOHA 4UNFA 1N3CA 1YQKA 3OH6A 4DK9A 4AI5A 4YOQA 4UOBA 1M3QA 2NOLA 2NOIA 3I0XA 1KG5A 3F0ZA 4EVVA 3IH7A 1ORNA 4E9HA 1EBMA 1XG7A 3OH9A 4OFEA 4EW4A 1KEAA 5KN9A 1KG2A 3OGDA 1RRSA 1PU6A 3KTUA 1KO9A 2I5WA 2OFKA 3F10A 1KG4A 1P7MA 3CWUA 2JHJA 3FSPA 4EJYA 4E9GA 2H56A 1FN7A 1RRQA 4E9EA 1YQRA 2OFIA 2ABKA 1NGNA 1XQPA 4E9FA 1LWVA 5KN8A 3N0UA 1KG7A 4OFAA 1KG6A 1P59A 4B23A 1XQOA 1MUDA 1N3AA 3CWSA 2NOEA 3KNTA 1PVSA 3CVTA 4PIIA 1LWWA 1PU8A 3N5NX 4HSBA 1LWYA 4OFHA 4B24A 3CWAA 3CW7A 4AI4A 3D4VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MUY A;  1YQM A;  2YG8 A;  1PU7 A;  1YQL A;  2YG9 A;  3G0Q A;  5CHZ A;  1DIZ A;  4EA4 A;  1VRL A;  4B22 A;  1MPG A;  5DPK A;  4YPH A;  3IHO A;  3S6I A;  1WEF A;  1WEI A;  3FHG A;  4AIA A;  1ORP A;  4EJZ A;  2NOB A;  4EW0 A;  1HU0 A;  5AN4 A;  3I0W A;  3CVS A;  1MUN A;  2JHN A;  2JG6 A;  1WEG A;  2NOF A;  1M3H A;  3CWT A;  2XHI A;  4EA5 A;  2NOZ A;  1KG3 A;  4YPR A;  1N39 A;  1KQJ A;  1LMZ A;  3FHF A;  1NKU A;  4B21 A;  2NOH A;  4UNF A;  1N3C A;  1YQK A;  3OH6 A;  4DK9 A;  4AI5 A;  4YOQ A;  4UOB A;  1M3Q A;  2NOL A;  2NOI A;  3I0X A;  1KG5 A;  3F0Z A;  4EVV A;  3IH7 A;  1ORN A;  4E9H A;  1EBM A;  1XG7 A;  3OH9 A;  4OFE A;  4EW4 A;  1KEA A;  5KN9 A;  1KG2 A;  3OGD A;  1RRS A;  1PU6 A;  3KTU A;  1KO9 A;  2I5W A;  2OFK A;  3F10 A;  1KG4 A;  1P7M A;  3CWU A;  2JHJ A;  3FSP A;  4EJY A;  4E9G A;  2H56 A;  1FN7 A;  1RRQ A;  4E9E A;  1YQR A;  2OFI A;  2ABK A;  1NGN A;  1XQP A;  4E9F A;  1LWV A;  5KN8 A;  3N0U A;  1KG7 A;  4OFA A;  1KG6 A;  1P59 A;  4B23 A;  1XQO A;  1MUD A;  1N3A A;  3CWS A;  2NOE A;  3KNT A;  1PVS A;  3CVT A;  4PII A;  1LWW A;  1PU8 A;  3N5N X;  4HSB A;  1LWY A;  4OFH A;  4B24 A;  3CWA A;  3CW7 A;  4AI4 A;  3D4V A; 
#chains in the Genus database with same CATH topology
 1MUY A;  1YQM A;  2YG8 A;  1PU7 A;  1YQL A;  3LCN A;  2YG9 A;  3G0Q A;  5CHZ A;  5FRN A;  4E7H A;  3OYN A;  4BE2 A;  1DIZ A;  3L2U A;  4EA4 A;  1VRL A;  4B22 A;  1MPG A;  4E7K A;  5DPK A;  4YPH A;  3IHO A;  3S6I A;  1WEF A;  1WEI A;  3FHG A;  4AIA A;  1ORP A;  4EJZ A;  2NOB A;  4EW0 A;  3L2V A;  1HU0 A;  3R2X C;  5AN4 A;  3S3N A;  3S3M A;  3I0W A;  3L2W A;  4E7I A;  3CVS A;  1MUN A;  4BE1 A;  2JHN A;  2JG6 A;  3L2R A;  1U84 A;  1WEG A;  4NZG A;  4E7J A;  4ZTJ A;  2NOF A;  4BE0 A;  1M3H A;  3OYD A;  2XHI A;  4EA5 A;  3CWT A;  2NOZ A;  1KG3 A;  2JPS A;  4YPR A;  1N39 A;  2W04 A;  1KQJ A;  1LMZ A;  3FHF A;  1NKU A;  3OY9 A;  4B21 A;  2NOH A;  4UNF A;  1N3C A;  1YQK A;  3OYI A;  4BDY A;  3OH6 A;  3NNQ A;  4DK9 A;  4AI5 A;  4YOQ A;  4UOB A;  1M3Q A;  5FRM A;  2NOL A;  3OYL A;  2NOI A;  3I0X A;  1KG5 A;  3F0Z A;  4EVV A;  3IH7 A;  1ORN A;  2W03 A;  4E9H A;  1EBM A;  1XG7 A;  3OH9 A;  4OFE A;  4EW4 A;  1KEA A;  5KN9 A;  3OS2 A;  3OYM A;  1KG2 A;  3OGD A;  1RRS A;  1PU6 A;  3OYH A;  3KTU A;  1KO9 A;  3OYE A;  2I5W A;  2OFK A;  3F10 A;  1KG4 A;  1P7M A;  3CWU A;  4BDZ A;  2JHJ A;  4E7L A;  3FSP A;  4EJY A;  4E9G A;  2H56 A;  3OYK A;  1FN7 A;  1RRQ A;  4E9E A;  1YQR A;  2OFI A;  2ABK A;  1NGN A;  1XQP A;  5FRO A;  4E9F A;  1LWV A;  5KN8 A;  3N0U A;  3S3O A;  3L2Q A;  1KG7 A;  4OFA A;  3OYF A;  1KG6 A;  2V75 A;  3OS0 A;  1P59 A;  4IKF A;  4B23 A;  1XQO A;  1MUD A;  1N3A A;  3CWS A;  3VW4 A;  2NOE A;  3OS1 A;  3KNT A;  4BAC A;  4ZTF A;  1PVS A;  3OYC A;  3OYG A;  3OYB A;  3OYA A;  3CVT A;  3OYJ A;  4PII A;  1LWW A;  1PU8 A;  3N5N X;  4HSB A;  1LWY A;  4OFH A;  4B24 A;  3CWA A;  3CW7 A;  4AI4 A;  3D4V A; 
#chains in the Genus database with same CATH homology
 1MUY A;  1YQM A;  2YG8 A;  1PU7 A;  1YQL A;  2YG9 A;  3G0Q A;  5CHZ A;  1DIZ A;  4EA4 A;  1VRL A;  4B22 A;  1MPG A;  5DPK A;  4YPH A;  3IHO A;  3S6I A;  1WEF A;  1WEI A;  3FHG A;  4AIA A;  1ORP A;  4EJZ A;  2NOB A;  4EW0 A;  1HU0 A;  5AN4 A;  3I0W A;  3CVS A;  1MUN A;  2JHN A;  2JG6 A;  1WEG A;  2NOF A;  1M3H A;  3CWT A;  2XHI A;  4EA5 A;  2NOZ A;  1KG3 A;  4YPR A;  1N39 A;  1KQJ A;  1LMZ A;  3FHF A;  1NKU A;  4B21 A;  2NOH A;  4UNF A;  1N3C A;  1YQK A;  3OH6 A;  4DK9 A;  4AI5 A;  4YOQ A;  4UOB A;  1M3Q A;  2NOL A;  2NOI A;  3I0X A;  1KG5 A;  3F0Z A;  4EVV A;  3IH7 A;  1ORN A;  4E9H A;  1EBM A;  1XG7 A;  3OH9 A;  4OFE A;  4EW4 A;  1KEA A;  5KN9 A;  1KG2 A;  3OGD A;  1RRS A;  1PU6 A;  3KTU A;  1KO9 A;  2I5W A;  2OFK A;  3F10 A;  1KG4 A;  1P7M A;  3CWU A;  2JHJ A;  3FSP A;  4EJY A;  4E9G A;  2H56 A;  1FN7 A;  1RRQ A;  4E9E A;  1YQR A;  2OFI A;  2ABK A;  1NGN A;  1XQP A;  4E9F A;  1LWV A;  5KN8 A;  3N0U A;  1KG7 A;  4OFA A;  1KG6 A;  1P59 A;  4B23 A;  1XQO A;  1MUD A;  1N3A A;  3CWS A;  2NOE A;  3KNT A;  1PVS A;  3CVT A;  4PII A;  1LWW A;  1PU8 A;  3N5N X;  4HSB A;  1LWY A;  4OFH A;  4B24 A;  3CWA A;  3CW7 A;  4AI4 A;  3D4V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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