1XQPA

Crystal structure of 8-oxoguanosine complexed pa-agog, 8-oxoguanine dna glycosylase from pyrobaculum aerophilum
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
252
structure length
252
Chain Sequence
AESQLKRVIETLRRLGIEEVLKLERRDPQYRAVCNVVKRHGETVGSRLAMLNALISYRLTGKGEEHWEYFGKYFSQLEVIDLCRDFLKYIETSPFLKIGVEARKKRALKACDYVPNLEDLGLTLRQLSHIVGARREQKTLVFTIKILNYAYMCSRGVNRVLPFDIPIPVDYRVARLTWCAGLIDFPPEEALRRYEAVQKIWDAVARETGIPPLHLDTLLWLAGRAVLYGENLHGVPKEVIALFQWRGGCRPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords 8-oxoguanine DNA glycosylase
publication title A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
pubmed doi rcsb
source organism Pyrobaculum aerophilum
total genus 95
structure length 252
sequence length 252
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09171 AGOG N-glycosylase/DNA lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1xqpA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1xqpA01
1EBMA 3G0QA 1WEIA 4B21A 4EJYA 3CW7A 2I5WA 1WEFA 1KG3A 4OFAA 4OFHA 1MUDA 2OFKA 1KO9A 5KN8A 1PVSA 3CWUA 3S6IA 2YG9A 1N3CA 4B22A 1LMZA 4DK9A 1KEAA 3KTUA 4YPRA 3CWSA 4YPHA 2NOZA 2JHNA 3OGDA 2NOIA 4EVVA 2ABKA 3FSPA 4B23A 4YOQA 3OH6A 4E9HA 1M3HA 1KG5A 1PU7A 3N5NX 2JHJA 4E9GA 1YQRA 2NOEA 1NKUA 2NOBA 1KQJA 1PU6A 1YQMA 2YG8A 3I0XA 4UNFA 1MUNA 1KG2A 1RRQA 4EW4A 1NGNA 5CHZA 1KG7A 4HSBA 1PU8A 3IHOA 3F10A 4EA4A 3IH7A 2JG6A 4OFEA 4E9FA 1LWYA 1ORNA 2H56A 2XHIA 1YQLA 3CWTA 1DIZA 3N0UA 1KG4A 3CVTA 2NOFA 2NOLA 4EA5A 4PIIA 3D4VA 1ORPA 1P7MA 1M3QA 1HU0A 3F0ZA 1P59A 1FN7A 1N39A 1XQPA 2NOHA 1N3AA 1VRLA 4E9EA 4UOBA 1MPGA 1XQOA 3FHFA 1MUYA 4EW0A 3OH9A 1KG6A 4EJZA 3I0WA 3FHGA 1LWVA 4AI5A 1YQKA 1LWWA 2OFIA 3CWAA 4B24A 5KN9A 5AN4A 4AI4A 1WEGA 3CVSA 1XG7A 4AIAA 5DPKA 1RRSA 3KNTA
chains in the Genus database with same CATH superfamily
3OYAA 3L2WA 1EBMA 3G0QA 4BACA 1WEIA 4B21A 4EJYA 3CW7A 2I5WA 1WEFA 3OYNA 1KG3A 4OFAA 3VW4A 4OFHA 3OY9A 1MUDA 4E7HA 2OFKA 1KO9A 5KN8A 1PVSA 2V75A 3CWUA 3S6IA 2YG9A 3OYJA 1N3CA 4BDYA 4B22A 1LMZA 4DK9A 1KEAA 3KTUA 4YPRA 3CWSA 4YPHA 3S3NA 3L2QA 2NOZA 2JHNA 3OGDA 2NOIA 3OYDA 4EVVA 4IKFA 2ABKA 2W03A 3FSPA 4B23A 4YOQA 3OH6A 4E9HA 4E7IA 3OYFA 1M3HA 1KG5A 1PU7A 3N5NX 2JHJA 4E9GA 3OYBA 1YQRA 2NOEA 1NKUA 2NOBA 1KQJA 1PU6A 1YQMA 2YG8A 3I0XA 4UNFA 3OYEA 1MUNA 1KG2A 1RRQA 3OYLA 3OYHA 3L2VA 4EW4A 1NGNA 5CHZA 1KG7A 4HSBA 1PU8A 3IHOA 3F10A 4EA4A 3IH7A 3OYKA 2JG6A 4OFEA 4E9FA 1LWYA 1ORNA 2H56A 2XHIA 1YQLA 3CWTA 3OYMA 1DIZA 3L2RA 4NZGA 3N0UA 1KG4A 5FRMA 3CVTA 4BDZA 2NOFA 3LCNA 4BE2A 2NOLA 1U84A 4EA5A 4PIIA 4BE1A 3D4VA 1ORPA 3OS0A 1P7MA 3L2UA 3S3OA 1M3QA 1HU0A 3F0ZA 4E7LA 1P59A 1FN7A 1N39A 4ZTJA 1XQPA 4E7KA 2NOHA 1N3AA 5FRNA 1VRLA 3OS1A 4E9EA 2JPSA 4UOBA 1MPGA 5FROA 1XQOA 4E7JA 4ZTFA 3FHFA 3OS2A 3S3MA 1MUYA 3OYGA 4EW0A 3NNQA 1KG6A 3OH9A 4EJZA 3I0WA 4BE0A 3FHGA 1LWVA 4AI5A 1YQKA 1LWWA 3R2XC 3CWAA 5KN9A 3OYIA 4B24A 3OYCA 2OFIA 5AN4A 4AI4A 1WEGA 3CVSA 1XG7A 2W04A 4AIAA 5DPKA 1RRSA 3KNTA
chains in the Genus database with same CATH topology
1EBMA 3G0QA 1WEIA 4B21A 4EJYA 3CW7A 2I5WA 1WEFA 1KG3A 4OFAA 4OFHA 1MUDA 2OFKA 1KO9A 5KN8A 1PVSA 3CWUA 3S6IA 2YG9A 1N3CA 4B22A 1LMZA 4DK9A 1KEAA 3KTUA 4YPRA 3CWSA 4YPHA 2NOZA 2JHNA 3OGDA 2NOIA 4EVVA 2ABKA 3FSPA 4B23A 4YOQA 3OH6A 4E9HA 1M3HA 1KG5A 1PU7A 3N5NX 2JHJA 4E9GA 1YQRA 2NOEA 1NKUA 2NOBA 1KQJA 1PU6A 1YQMA 2YG8A 3I0XA 4UNFA 1MUNA 1KG2A 1RRQA 4EW4A 1NGNA 5CHZA 1KG7A 4HSBA 1PU8A 3IHOA 3F10A 4EA4A 3IH7A 2JG6A 4OFEA 4E9FA 1LWYA 1ORNA 2H56A 2XHIA 1YQLA 3CWTA 1DIZA 3N0UA 1KG4A 3CVTA 2NOFA 2NOLA 4EA5A 4PIIA 3D4VA 1ORPA 1P7MA 1M3QA 1HU0A 3F0ZA 1P59A 1FN7A 1N39A 1XQPA 2NOHA 1N3AA 1VRLA 4E9EA 4UOBA 1MPGA 1XQOA 3FHFA 1MUYA 4EW0A 3OH9A 1KG6A 4EJZA 3I0WA 3FHGA 1LWVA 4AI5A 1YQKA 1LWWA 2OFIA 3CWAA 4B24A 5KN9A 5AN4A 4AI4A 1WEGA 3CVSA 1XG7A 4AIAA 5DPKA 1RRSA 3KNTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EBM A;  3G0Q A;  1WEI A;  4B21 A;  4EJY A;  3CW7 A;  2I5W A;  1WEF A;  1KG3 A;  4OFA A;  4OFH A;  1MUD A;  2OFK A;  1KO9 A;  5KN8 A;  1PVS A;  3CWU A;  3S6I A;  2YG9 A;  1N3C A;  4B22 A;  1LMZ A;  4DK9 A;  1KEA A;  3KTU A;  4YPR A;  3CWS A;  4YPH A;  2NOZ A;  2JHN A;  3OGD A;  2NOI A;  4EVV A;  2ABK A;  3FSP A;  4B23 A;  4YOQ A;  3OH6 A;  4E9H A;  1M3H A;  1KG5 A;  1PU7 A;  3N5N X;  2JHJ A;  4E9G A;  1YQR A;  2NOE A;  1NKU A;  2NOB A;  1KQJ A;  1PU6 A;  1YQM A;  2YG8 A;  3I0X A;  4UNF A;  1MUN A;  1KG2 A;  1RRQ A;  4EW4 A;  1NGN A;  5CHZ A;  1KG7 A;  4HSB A;  1PU8 A;  3IHO A;  3F10 A;  4EA4 A;  3IH7 A;  2JG6 A;  4OFE A;  4E9F A;  1LWY A;  1ORN A;  2H56 A;  2XHI A;  1YQL A;  3CWT A;  1DIZ A;  3N0U A;  1KG4 A;  3CVT A;  2NOF A;  2NOL A;  4EA5 A;  4PII A;  3D4V A;  1ORP A;  1P7M A;  1M3Q A;  1HU0 A;  3F0Z A;  1P59 A;  1FN7 A;  1N39 A;  1XQP A;  2NOH A;  1N3A A;  1VRL A;  4E9E A;  4UOB A;  1MPG A;  1XQO A;  3FHF A;  1MUY A;  4EW0 A;  3OH9 A;  1KG6 A;  4EJZ A;  3I0W A;  3FHG A;  1LWV A;  4AI5 A;  1YQK A;  1LWW A;  2OFI A;  3CWA A;  4B24 A;  5KN9 A;  5AN4 A;  4AI4 A;  1WEG A;  3CVS A;  1XG7 A;  4AIA A;  5DPK A;  1RRS A;  3KNT A; 
#chains in the Genus database with same CATH topology
 3OYA A;  3L2W A;  1EBM A;  3G0Q A;  4BAC A;  1WEI A;  4B21 A;  4EJY A;  3CW7 A;  2I5W A;  1WEF A;  3OYN A;  1KG3 A;  4OFA A;  3VW4 A;  4OFH A;  3OY9 A;  1MUD A;  4E7H A;  2OFK A;  1KO9 A;  5KN8 A;  1PVS A;  2V75 A;  3CWU A;  3S6I A;  2YG9 A;  3OYJ A;  1N3C A;  4BDY A;  4B22 A;  1LMZ A;  4DK9 A;  1KEA A;  3KTU A;  4YPR A;  3CWS A;  4YPH A;  3S3N A;  3L2Q A;  2NOZ A;  2JHN A;  3OGD A;  2NOI A;  3OYD A;  4EVV A;  4IKF A;  2ABK A;  2W03 A;  3FSP A;  4B23 A;  4YOQ A;  3OH6 A;  4E9H A;  4E7I A;  3OYF A;  1M3H A;  1KG5 A;  1PU7 A;  3N5N X;  2JHJ A;  4E9G A;  3OYB A;  1YQR A;  2NOE A;  1NKU A;  2NOB A;  1KQJ A;  1PU6 A;  1YQM A;  2YG8 A;  3I0X A;  4UNF A;  3OYE A;  1MUN A;  1KG2 A;  1RRQ A;  3OYL A;  3OYH A;  3L2V A;  4EW4 A;  1NGN A;  5CHZ A;  1KG7 A;  4HSB A;  1PU8 A;  3IHO A;  3F10 A;  4EA4 A;  3IH7 A;  3OYK A;  2JG6 A;  4OFE A;  4E9F A;  1LWY A;  1ORN A;  2H56 A;  2XHI A;  1YQL A;  3CWT A;  3OYM A;  1DIZ A;  3L2R A;  4NZG A;  3N0U A;  1KG4 A;  5FRM A;  3CVT A;  4BDZ A;  2NOF A;  3LCN A;  4BE2 A;  2NOL A;  1U84 A;  4EA5 A;  4PII A;  4BE1 A;  3D4V A;  1ORP A;  3OS0 A;  1P7M A;  3L2U A;  3S3O A;  1M3Q A;  1HU0 A;  3F0Z A;  4E7L A;  1P59 A;  1FN7 A;  1N39 A;  4ZTJ A;  1XQP A;  4E7K A;  2NOH A;  1N3A A;  5FRN A;  1VRL A;  3OS1 A;  4E9E A;  2JPS A;  4UOB A;  1MPG A;  5FRO A;  1XQO A;  4E7J A;  4ZTF A;  3FHF A;  3OS2 A;  3S3M A;  1MUY A;  3OYG A;  4EW0 A;  3NNQ A;  1KG6 A;  3OH9 A;  4EJZ A;  3I0W A;  4BE0 A;  3FHG A;  1LWV A;  4AI5 A;  1YQK A;  1LWW A;  3R2X C;  3CWA A;  5KN9 A;  3OYI A;  4B24 A;  3OYC A;  2OFI A;  5AN4 A;  4AI4 A;  1WEG A;  3CVS A;  1XG7 A;  2W04 A;  4AIA A;  5DPK A;  1RRS A;  3KNT A; 
#chains in the Genus database with same CATH homology
 1EBM A;  3G0Q A;  1WEI A;  4B21 A;  4EJY A;  3CW7 A;  2I5W A;  1WEF A;  1KG3 A;  4OFA A;  4OFH A;  1MUD A;  2OFK A;  1KO9 A;  5KN8 A;  1PVS A;  3CWU A;  3S6I A;  2YG9 A;  1N3C A;  4B22 A;  1LMZ A;  4DK9 A;  1KEA A;  3KTU A;  4YPR A;  3CWS A;  4YPH A;  2NOZ A;  2JHN A;  3OGD A;  2NOI A;  4EVV A;  2ABK A;  3FSP A;  4B23 A;  4YOQ A;  3OH6 A;  4E9H A;  1M3H A;  1KG5 A;  1PU7 A;  3N5N X;  2JHJ A;  4E9G A;  1YQR A;  2NOE A;  1NKU A;  2NOB A;  1KQJ A;  1PU6 A;  1YQM A;  2YG8 A;  3I0X A;  4UNF A;  1MUN A;  1KG2 A;  1RRQ A;  4EW4 A;  1NGN A;  5CHZ A;  1KG7 A;  4HSB A;  1PU8 A;  3IHO A;  3F10 A;  4EA4 A;  3IH7 A;  2JG6 A;  4OFE A;  4E9F A;  1LWY A;  1ORN A;  2H56 A;  2XHI A;  1YQL A;  3CWT A;  1DIZ A;  3N0U A;  1KG4 A;  3CVT A;  2NOF A;  2NOL A;  4EA5 A;  4PII A;  3D4V A;  1ORP A;  1P7M A;  1M3Q A;  1HU0 A;  3F0Z A;  1P59 A;  1FN7 A;  1N39 A;  1XQP A;  2NOH A;  1N3A A;  1VRL A;  4E9E A;  4UOB A;  1MPG A;  1XQO A;  3FHF A;  1MUY A;  4EW0 A;  3OH9 A;  1KG6 A;  4EJZ A;  3I0W A;  3FHG A;  1LWV A;  4AI5 A;  1YQK A;  1LWW A;  2OFI A;  3CWA A;  4B24 A;  5KN9 A;  5AN4 A;  4AI4 A;  1WEG A;  3CVS A;  1XG7 A;  4AIA A;  5DPK A;  1RRS A;  3KNT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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