1KG6A

Crystal structure of the k142r mutant of e.coli muty (core fragment)
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVRRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 78
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg6A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg6A01
3I0XA 1XG7A 1N3CA 1M3QA 1KO9A 1RRSA 3S6IA 4EVVA 3CWAA 3FHFA 1MPGA 1HU0A 4E9EA 4EW4A 4YOQA 3KNTA 1P7MA 1WEGA 4E9HA 3CWSA 2I5WA 1RRQA 1NGNA 2OFKA 1N3AA 4AI5A 3D4VA 3F10A 3F0ZA 4PIIA 1LWYA 2YG9A 1KQJA 1LMZA 2ABKA 1YQKA 4AIAA 4EA5A 4E9GA 1FN7A 4E9FA 1MUNA 1KG3A 3OH9A 2JHJA 1MUDA 1KG2A 1KG7A 2JHNA 2NOBA 4DK9A 1ORNA 2YG8A 4AI4A 4B21A 5CHZA 1YQRA 2NOZA 1P59A 3KTUA 3OGDA 3FSPA 1ORPA 4B22A 2XHIA 1MUYA 4EA4A 2H56A 2NOFA 1KG4A 4YPRA 1NKUA 1N39A 4OFEA 1LWVA 1PU7A 1YQMA 4UOBA 5AN4A 1VRLA 5KN8A 1LWWA 3CW7A 3CVSA 4EJZA 5DPKA 4OFHA 4YPHA 1DIZA 3CWTA 1PVSA 2NOLA 1XQOA 5KN9A 4EW0A 1KG5A 4HSBA 2NOEA 3G0QA 2NOIA 3I0WA 4EJYA 4B23A 2NOHA 1XQPA 1PU6A 1EBMA 3N5NX 3OH6A 1KEAA 1WEIA 4B24A 4UNFA 2JG6A 3IHOA 1M3HA 4OFAA 3CVTA 3IH7A 1PU8A 3N0UA 1KG6A 2OFIA 1WEFA 1YQLA 3FHGA 3CWUA
chains in the Genus database with same CATH superfamily
3I0XA 3L2UA 1XG7A 3S3MA 4ZTJA 1N3CA 1M3QA 1KO9A 3S3NA 1RRSA 3S6IA 4BE2A 4EVVA 2W03A 4E7LA 3CWAA 3FHFA 1MPGA 1HU0A 4E9EA 4E7IA 4EW4A 4YOQA 3KNTA 1P7MA 1WEGA 4E9HA 3L2QA 3CWSA 4E7KA 2I5WA 2JPSA 1RRQA 5FRNA 3OYJA 1NGNA 2OFKA 3LCNA 3OS1A 4BACA 1N3AA 3OYNA 3OYMA 4AI5A 3D4VA 3F10A 3F0ZA 3OYLA 4PIIA 1LWYA 2YG9A 1KQJA 3OYEA 1LMZA 2ABKA 1YQKA 4AIAA 4EA5A 4E9GA 1FN7A 4E9FA 3OYIA 1MUNA 1KG3A 3OH9A 2JHJA 1MUDA 1KG2A 1KG7A 4NZGA 3R2XC 2JHNA 3OYDA 1U84A 2NOBA 3S3OA 4DK9A 3OS0A 4ZTFA 1ORNA 2YG8A 4AI4A 4BDYA 4B21A 5CHZA 4E7JA 4BE0A 1YQRA 4BE1A 2NOZA 1P59A 3L2VA 3KTUA 3OGDA 3NNQA 3FSPA 1ORPA 4B22A 2XHIA 1MUYA 2V75A 3OYGA 3OYKA 3OYCA 4EA4A 2H56A 2NOFA 1KG4A 3OYBA 4YPRA 1NKUA 1N39A 3OS2A 4OFEA 5FROA 1LWVA 1PU7A 1YQMA 4UOBA 5AN4A 1VRLA 5KN8A 1LWWA 3CW7A 3CVSA 4EJZA 5DPKA 4OFHA 4YPHA 1DIZA 3CWTA 1PVSA 2NOLA 1XQOA 5KN9A 4EW0A 1KG5A 3OY9A 3OYAA 4HSBA 2NOEA 3G0QA 2NOIA 3I0WA 4EJYA 4B23A 2NOHA 1XQPA 1PU6A 3OYHA 1EBMA 3N5NX 3OH6A 3OYFA 1KEAA 3VW4A 5FRMA 1WEIA 4E7HA 4B24A 4UNFA 2JG6A 3IHOA 1M3HA 4OFAA 3CVTA 3L2RA 3IH7A 4IKFA 1PU8A 3L2WA 3N0UA 1KG6A 2OFIA 1WEFA 4BDZA 1YQLA 2W04A 3FHGA 3CWUA
chains in the Genus database with same CATH topology
3I0XA 1XG7A 1N3CA 1M3QA 1KO9A 1RRSA 3S6IA 4EVVA 3CWAA 3FHFA 1MPGA 1HU0A 4E9EA 4EW4A 4YOQA 3KNTA 1P7MA 1WEGA 4E9HA 3CWSA 2I5WA 1RRQA 1NGNA 2OFKA 1N3AA 4AI5A 3D4VA 3F10A 3F0ZA 4PIIA 1LWYA 2YG9A 1KQJA 1LMZA 2ABKA 1YQKA 4AIAA 4EA5A 4E9GA 1FN7A 4E9FA 1MUNA 1KG3A 3OH9A 2JHJA 1MUDA 1KG2A 1KG7A 2JHNA 2NOBA 4DK9A 1ORNA 2YG8A 4AI4A 4B21A 5CHZA 1YQRA 2NOZA 1P59A 3KTUA 3OGDA 3FSPA 1ORPA 4B22A 2XHIA 1MUYA 4EA4A 2H56A 2NOFA 1KG4A 4YPRA 1NKUA 1N39A 4OFEA 1LWVA 1PU7A 1YQMA 4UOBA 5AN4A 1VRLA 5KN8A 1LWWA 3CW7A 3CVSA 4EJZA 5DPKA 4OFHA 4YPHA 1DIZA 3CWTA 1PVSA 2NOLA 1XQOA 5KN9A 4EW0A 1KG5A 4HSBA 2NOEA 3G0QA 2NOIA 3I0WA 4EJYA 4B23A 2NOHA 1XQPA 1PU6A 1EBMA 3N5NX 3OH6A 1KEAA 1WEIA 4B24A 4UNFA 2JG6A 3IHOA 1M3HA 4OFAA 3CVTA 3IH7A 1PU8A 3N0UA 1KG6A 2OFIA 1WEFA 1YQLA 3FHGA 3CWUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I0X A;  1XG7 A;  1N3C A;  1M3Q A;  1KO9 A;  1RRS A;  3S6I A;  4EVV A;  3CWA A;  3FHF A;  1MPG A;  1HU0 A;  4E9E A;  4EW4 A;  4YOQ A;  3KNT A;  1P7M A;  1WEG A;  4E9H A;  3CWS A;  2I5W A;  1RRQ A;  1NGN A;  2OFK A;  1N3A A;  4AI5 A;  3D4V A;  3F10 A;  3F0Z A;  4PII A;  1LWY A;  2YG9 A;  1KQJ A;  1LMZ A;  2ABK A;  1YQK A;  4AIA A;  4EA5 A;  4E9G A;  1FN7 A;  4E9F A;  1MUN A;  1KG3 A;  3OH9 A;  2JHJ A;  1MUD A;  1KG2 A;  1KG7 A;  2JHN A;  2NOB A;  4DK9 A;  1ORN A;  2YG8 A;  4AI4 A;  4B21 A;  5CHZ A;  1YQR A;  2NOZ A;  1P59 A;  3KTU A;  3OGD A;  3FSP A;  1ORP A;  4B22 A;  2XHI A;  1MUY A;  4EA4 A;  2H56 A;  2NOF A;  1KG4 A;  4YPR A;  1NKU A;  1N39 A;  4OFE A;  1LWV A;  1PU7 A;  1YQM A;  4UOB A;  5AN4 A;  1VRL A;  5KN8 A;  1LWW A;  3CW7 A;  3CVS A;  4EJZ A;  5DPK A;  4OFH A;  4YPH A;  1DIZ A;  3CWT A;  1PVS A;  2NOL A;  1XQO A;  5KN9 A;  4EW0 A;  1KG5 A;  4HSB A;  2NOE A;  3G0Q A;  2NOI A;  3I0W A;  4EJY A;  4B23 A;  2NOH A;  1XQP A;  1PU6 A;  1EBM A;  3N5N X;  3OH6 A;  1KEA A;  1WEI A;  4B24 A;  4UNF A;  2JG6 A;  3IHO A;  1M3H A;  4OFA A;  3CVT A;  3IH7 A;  1PU8 A;  3N0U A;  1KG6 A;  2OFI A;  1WEF A;  1YQL A;  3FHG A;  3CWU A; 
#chains in the Genus database with same CATH topology
 3I0X A;  3L2U A;  1XG7 A;  3S3M A;  4ZTJ A;  1N3C A;  1M3Q A;  1KO9 A;  3S3N A;  1RRS A;  3S6I A;  4BE2 A;  4EVV A;  2W03 A;  4E7L A;  3CWA A;  3FHF A;  1MPG A;  1HU0 A;  4E9E A;  4E7I A;  4EW4 A;  4YOQ A;  3KNT A;  1P7M A;  1WEG A;  4E9H A;  3L2Q A;  3CWS A;  4E7K A;  2I5W A;  2JPS A;  1RRQ A;  5FRN A;  3OYJ A;  1NGN A;  2OFK A;  3LCN A;  3OS1 A;  4BAC A;  1N3A A;  3OYN A;  3OYM A;  4AI5 A;  3D4V A;  3F10 A;  3F0Z A;  3OYL A;  4PII A;  1LWY A;  2YG9 A;  1KQJ A;  3OYE A;  1LMZ A;  2ABK A;  1YQK A;  4AIA A;  4EA5 A;  4E9G A;  1FN7 A;  4E9F A;  3OYI A;  1MUN A;  1KG3 A;  3OH9 A;  2JHJ A;  1MUD A;  1KG2 A;  1KG7 A;  4NZG A;  3R2X C;  2JHN A;  3OYD A;  1U84 A;  2NOB A;  3S3O A;  4DK9 A;  3OS0 A;  4ZTF A;  1ORN A;  2YG8 A;  4AI4 A;  4BDY A;  4B21 A;  5CHZ A;  4E7J A;  4BE0 A;  1YQR A;  4BE1 A;  2NOZ A;  1P59 A;  3L2V A;  3KTU A;  3OGD A;  3NNQ A;  3FSP A;  1ORP A;  4B22 A;  2XHI A;  1MUY A;  2V75 A;  3OYG A;  3OYK A;  3OYC A;  4EA4 A;  2H56 A;  2NOF A;  1KG4 A;  3OYB A;  4YPR A;  1NKU A;  1N39 A;  3OS2 A;  4OFE A;  5FRO A;  1LWV A;  1PU7 A;  1YQM A;  4UOB A;  5AN4 A;  1VRL A;  5KN8 A;  1LWW A;  3CW7 A;  3CVS A;  4EJZ A;  5DPK A;  4OFH A;  4YPH A;  1DIZ A;  3CWT A;  1PVS A;  2NOL A;  1XQO A;  5KN9 A;  4EW0 A;  1KG5 A;  3OY9 A;  3OYA A;  4HSB A;  2NOE A;  3G0Q A;  2NOI A;  3I0W A;  4EJY A;  4B23 A;  2NOH A;  1XQP A;  1PU6 A;  3OYH A;  1EBM A;  3N5N X;  3OH6 A;  3OYF A;  1KEA A;  3VW4 A;  5FRM A;  1WEI A;  4E7H A;  4B24 A;  4UNF A;  2JG6 A;  3IHO A;  1M3H A;  4OFA A;  3CVT A;  3L2R A;  3IH7 A;  4IKF A;  1PU8 A;  3L2W A;  3N0U A;  1KG6 A;  2OFI A;  1WEF A;  4BDZ A;  1YQL A;  2W04 A;  3FHG A;  3CWU A; 
#chains in the Genus database with same CATH homology
 3I0X A;  1XG7 A;  1N3C A;  1M3Q A;  1KO9 A;  1RRS A;  3S6I A;  4EVV A;  3CWA A;  3FHF A;  1MPG A;  1HU0 A;  4E9E A;  4EW4 A;  4YOQ A;  3KNT A;  1P7M A;  1WEG A;  4E9H A;  3CWS A;  2I5W A;  1RRQ A;  1NGN A;  2OFK A;  1N3A A;  4AI5 A;  3D4V A;  3F10 A;  3F0Z A;  4PII A;  1LWY A;  2YG9 A;  1KQJ A;  1LMZ A;  2ABK A;  1YQK A;  4AIA A;  4EA5 A;  4E9G A;  1FN7 A;  4E9F A;  1MUN A;  1KG3 A;  3OH9 A;  2JHJ A;  1MUD A;  1KG2 A;  1KG7 A;  2JHN A;  2NOB A;  4DK9 A;  1ORN A;  2YG8 A;  4AI4 A;  4B21 A;  5CHZ A;  1YQR A;  2NOZ A;  1P59 A;  3KTU A;  3OGD A;  3FSP A;  1ORP A;  4B22 A;  2XHI A;  1MUY A;  4EA4 A;  2H56 A;  2NOF A;  1KG4 A;  4YPR A;  1NKU A;  1N39 A;  4OFE A;  1LWV A;  1PU7 A;  1YQM A;  4UOB A;  5AN4 A;  1VRL A;  5KN8 A;  1LWW A;  3CW7 A;  3CVS A;  4EJZ A;  5DPK A;  4OFH A;  4YPH A;  1DIZ A;  3CWT A;  1PVS A;  2NOL A;  1XQO A;  5KN9 A;  4EW0 A;  1KG5 A;  4HSB A;  2NOE A;  3G0Q A;  2NOI A;  3I0W A;  4EJY A;  4B23 A;  2NOH A;  1XQP A;  1PU6 A;  1EBM A;  3N5N X;  3OH6 A;  1KEA A;  1WEI A;  4B24 A;  4UNF A;  2JG6 A;  3IHO A;  1M3H A;  4OFA A;  3CVT A;  3IH7 A;  1PU8 A;  3N0U A;  1KG6 A;  2OFI A;  1WEF A;  1YQL A;  3FHG A;  3CWU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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