1KG6A

Crystal structure of the k142r mutant of e.coli muty (core fragment)
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVRRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
molecule keywords A/G-specific adenine glycosylase
total genus 78
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg6A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg6A01
3FHGA 3CWSA 4EJYA 3F0ZA 1MUYA 1DIZA 2YG8A 1PU6A 3G0QA 3IH7A 5CHZA 1KO9A 3FHFA 4OFEA 2I5WA 2NOEA 5KN8A 1NGNA 3CW7A 3CWTA 1KG7A 1MUNA 1LMZA 1EBMA 4YPHA 1ORPA 3I0XA 3D4VA 1YQKA 1N39A 1HU0A 1YQRA 1XQPA 4B23A 4EW0A 4EA5A 1PU7A 4B24A 4OFHA 2XHIA 1N3CA 1WEIA 1P59A 2NOIA 3CVTA 4YOQA 1NKUA 3FSPA 1MPGA 1XG7A 2NOLA 4PIIA 1KG5A 1KG2A 1MUDA 1P7MA 1KEAA 4E9EA 1WEFA 4B22A 3IHOA 4E9HA 1M3QA 4UOBA 3KNTA 2NOZA 2JG6A 4HSBA 4OFAA 1LWWA 4AIAA 1LWYA 1WEGA 4EVVA 1LWVA 3N0UA 4UNFA 3OGDA 1YQLA 1KG3A 1N3AA 4AI4A 4AI5A 1FN7A 2OFKA 1YQMA 1KQJA 1ORNA 1KG6A 4YPRA 3OH9A 1RRQA 2JHJA 4EJZA 3KTUA 3CVSA 4EW4A 2OFIA 5KN9A 3OH6A 5AN4A 2H56A 1VRLA 4DK9A 4E9GA 1PU8A 4EA4A 2ABKA 2YG9A 2NOFA 2NOBA 4E9FA 4B21A 3CWUA 1RRSA 2JHNA 1XQOA 1M3HA 3F10A 3N5NX 1PVSA 1KG4A 2NOHA 3CWAA 3I0WA 3S6IA 5DPKA
chains in the Genus database with same CATH superfamily
3FHGA 3OYAA 3CWSA 3F0ZA 4EJYA 1MUYA 2W04A 2YG8A 1DIZA 1PU6A 3G0QA 4BE1A 3IH7A 5CHZA 1KO9A 2W03A 3FHFA 4OFEA 2I5WA 2NOEA 3OYJA 5KN8A 4E7KA 1NGNA 3CW7A 3OYDA 3CWTA 1U84A 4NZGA 1KG7A 1MUNA 1LMZA 1EBMA 4YPHA 1ORPA 3I0XA 3D4VA 1YQKA 1N39A 1HU0A 1YQRA 1XQPA 3OS1A 4B23A 4EW0A 4BDZA 3VW4A 3OYNA 4EA5A 1PU7A 4B24A 4OFHA 2XHIA 1N3CA 1WEIA 4ZTJA 4ZTFA 3OYEA 1P59A 3CVTA 2NOIA 4YOQA 1NKUA 5FRNA 3FSPA 1MPGA 1XG7A 3OYMA 2NOLA 4PIIA 1KG5A 1KG2A 1MUDA 1P7MA 1KEAA 4E9EA 1WEFA 4B22A 3IHOA 4BACA 4E9HA 1M3QA 4UOBA 3KNTA 3L2VA 3OY9A 3L2UA 4BDYA 2JPSA 2NOZA 2JG6A 3OYCA 4HSBA 4OFAA 1LWWA 4AIAA 3R2XC 1LWYA 1WEGA 4EVVA 1LWVA 3N0UA 4UNFA 4E7LA 3OGDA 1YQLA 1KG3A 3OYGA 3OS0A 1N3AA 3S3OA 4AI4A 4AI5A 1FN7A 2OFKA 3OYBA 1YQMA 1KQJA 3OYFA 1ORNA 1KG6A 4YPRA 3OH9A 1RRQA 2JHJA 3OYKA 4IKFA 4BE0A 4EJZA 3KTUA 3CVSA 4EW4A 5FRMA 5FROA 2OFIA 5KN9A 4E7JA 3OYLA 3OH6A 3L2QA 3NNQA 5AN4A 2H56A 1VRLA 4DK9A 4E9GA 1PU8A 3OYHA 4EA4A 2ABKA 2YG9A 2NOFA 2V75A 4BE2A 2NOBA 4E9FA 4B21A 3CWUA 1RRSA 2JHNA 1XQOA 1M3HA 3F10A 3L2RA 3LCNA 4E7IA 3S3NA 3OS2A 4E7HA 3N5NX 1PVSA 1KG4A 3I0WA 2NOHA 3L2WA 3CWAA 3OYIA 3S6IA 3S3MA 5DPKA
chains in the Genus database with same CATH topology
3FHGA 3CWSA 4EJYA 3F0ZA 1MUYA 1DIZA 2YG8A 1PU6A 3G0QA 3IH7A 5CHZA 1KO9A 3FHFA 4OFEA 2I5WA 2NOEA 5KN8A 1NGNA 3CW7A 3CWTA 1KG7A 1MUNA 1LMZA 1EBMA 4YPHA 1ORPA 3I0XA 3D4VA 1YQKA 1N39A 1HU0A 1YQRA 1XQPA 4B23A 4EW0A 4EA5A 1PU7A 4B24A 4OFHA 2XHIA 1N3CA 1WEIA 1P59A 2NOIA 3CVTA 4YOQA 1NKUA 3FSPA 1MPGA 1XG7A 2NOLA 4PIIA 1KG5A 1KG2A 1MUDA 1P7MA 1KEAA 4E9EA 1WEFA 4B22A 3IHOA 4E9HA 1M3QA 4UOBA 3KNTA 2NOZA 2JG6A 4HSBA 4OFAA 1LWWA 4AIAA 1LWYA 1WEGA 4EVVA 1LWVA 3N0UA 4UNFA 3OGDA 1YQLA 1KG3A 1N3AA 4AI4A 4AI5A 1FN7A 2OFKA 1YQMA 1KQJA 1ORNA 1KG6A 4YPRA 3OH9A 1RRQA 2JHJA 4EJZA 3KTUA 3CVSA 4EW4A 2OFIA 5KN9A 3OH6A 5AN4A 2H56A 1VRLA 4DK9A 4E9GA 1PU8A 4EA4A 2ABKA 2YG9A 2NOFA 2NOBA 4E9FA 4B21A 3CWUA 1RRSA 2JHNA 1XQOA 1M3HA 3F10A 3N5NX 1PVSA 1KG4A 2NOHA 3CWAA 3I0WA 3S6IA 5DPKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FHG A;  3CWS A;  4EJY A;  3F0Z A;  1MUY A;  1DIZ A;  2YG8 A;  1PU6 A;  3G0Q A;  3IH7 A;  5CHZ A;  1KO9 A;  3FHF A;  4OFE A;  2I5W A;  2NOE A;  5KN8 A;  1NGN A;  3CW7 A;  3CWT A;  1KG7 A;  1MUN A;  1LMZ A;  1EBM A;  4YPH A;  1ORP A;  3I0X A;  3D4V A;  1YQK A;  1N39 A;  1HU0 A;  1YQR A;  1XQP A;  4B23 A;  4EW0 A;  4EA5 A;  1PU7 A;  4B24 A;  4OFH A;  2XHI A;  1N3C A;  1WEI A;  1P59 A;  2NOI A;  3CVT A;  4YOQ A;  1NKU A;  3FSP A;  1MPG A;  1XG7 A;  2NOL A;  4PII A;  1KG5 A;  1KG2 A;  1MUD A;  1P7M A;  1KEA A;  4E9E A;  1WEF A;  4B22 A;  3IHO A;  4E9H A;  1M3Q A;  4UOB A;  3KNT A;  2NOZ A;  2JG6 A;  4HSB A;  4OFA A;  1LWW A;  4AIA A;  1LWY A;  1WEG A;  4EVV A;  1LWV A;  3N0U A;  4UNF A;  3OGD A;  1YQL A;  1KG3 A;  1N3A A;  4AI4 A;  4AI5 A;  1FN7 A;  2OFK A;  1YQM A;  1KQJ A;  1ORN A;  1KG6 A;  4YPR A;  3OH9 A;  1RRQ A;  2JHJ A;  4EJZ A;  3KTU A;  3CVS A;  4EW4 A;  2OFI A;  5KN9 A;  3OH6 A;  5AN4 A;  2H56 A;  1VRL A;  4DK9 A;  4E9G A;  1PU8 A;  4EA4 A;  2ABK A;  2YG9 A;  2NOF A;  2NOB A;  4E9F A;  4B21 A;  3CWU A;  1RRS A;  2JHN A;  1XQO A;  1M3H A;  3F10 A;  3N5N X;  1PVS A;  1KG4 A;  2NOH A;  3CWA A;  3I0W A;  3S6I A;  5DPK A; 
#chains in the Genus database with same CATH topology
 3FHG A;  3OYA A;  3CWS A;  3F0Z A;  4EJY A;  1MUY A;  2W04 A;  2YG8 A;  1DIZ A;  1PU6 A;  3G0Q A;  4BE1 A;  3IH7 A;  5CHZ A;  1KO9 A;  2W03 A;  3FHF A;  4OFE A;  2I5W A;  2NOE A;  3OYJ A;  5KN8 A;  4E7K A;  1NGN A;  3CW7 A;  3OYD A;  3CWT A;  1U84 A;  4NZG A;  1KG7 A;  1MUN A;  1LMZ A;  1EBM A;  4YPH A;  1ORP A;  3I0X A;  3D4V A;  1YQK A;  1N39 A;  1HU0 A;  1YQR A;  1XQP A;  3OS1 A;  4B23 A;  4EW0 A;  4BDZ A;  3VW4 A;  3OYN A;  4EA5 A;  1PU7 A;  4B24 A;  4OFH A;  2XHI A;  1N3C A;  1WEI A;  4ZTJ A;  4ZTF A;  3OYE A;  1P59 A;  3CVT A;  2NOI A;  4YOQ A;  1NKU A;  5FRN A;  3FSP A;  1MPG A;  1XG7 A;  3OYM A;  2NOL A;  4PII A;  1KG5 A;  1KG2 A;  1MUD A;  1P7M A;  1KEA A;  4E9E A;  1WEF A;  4B22 A;  3IHO A;  4BAC A;  4E9H A;  1M3Q A;  4UOB A;  3KNT A;  3L2V A;  3OY9 A;  3L2U A;  4BDY A;  2JPS A;  2NOZ A;  2JG6 A;  3OYC A;  4HSB A;  4OFA A;  1LWW A;  4AIA A;  3R2X C;  1LWY A;  1WEG A;  4EVV A;  1LWV A;  3N0U A;  4UNF A;  4E7L A;  3OGD A;  1YQL A;  1KG3 A;  3OYG A;  3OS0 A;  1N3A A;  3S3O A;  4AI4 A;  4AI5 A;  1FN7 A;  2OFK A;  3OYB A;  1YQM A;  1KQJ A;  3OYF A;  1ORN A;  1KG6 A;  4YPR A;  3OH9 A;  1RRQ A;  2JHJ A;  3OYK A;  4IKF A;  4BE0 A;  4EJZ A;  3KTU A;  3CVS A;  4EW4 A;  5FRM A;  5FRO A;  2OFI A;  5KN9 A;  4E7J A;  3OYL A;  3OH6 A;  3L2Q A;  3NNQ A;  5AN4 A;  2H56 A;  1VRL A;  4DK9 A;  4E9G A;  1PU8 A;  3OYH A;  4EA4 A;  2ABK A;  2YG9 A;  2NOF A;  2V75 A;  4BE2 A;  2NOB A;  4E9F A;  4B21 A;  3CWU A;  1RRS A;  2JHN A;  1XQO A;  1M3H A;  3F10 A;  3L2R A;  3LCN A;  4E7I A;  3S3N A;  3OS2 A;  4E7H A;  3N5N X;  1PVS A;  1KG4 A;  3I0W A;  2NOH A;  3L2W A;  3CWA A;  3OYI A;  3S6I A;  3S3M A;  5DPK A; 
#chains in the Genus database with same CATH homology
 3FHG A;  3CWS A;  4EJY A;  3F0Z A;  1MUY A;  1DIZ A;  2YG8 A;  1PU6 A;  3G0Q A;  3IH7 A;  5CHZ A;  1KO9 A;  3FHF A;  4OFE A;  2I5W A;  2NOE A;  5KN8 A;  1NGN A;  3CW7 A;  3CWT A;  1KG7 A;  1MUN A;  1LMZ A;  1EBM A;  4YPH A;  1ORP A;  3I0X A;  3D4V A;  1YQK A;  1N39 A;  1HU0 A;  1YQR A;  1XQP A;  4B23 A;  4EW0 A;  4EA5 A;  1PU7 A;  4B24 A;  4OFH A;  2XHI A;  1N3C A;  1WEI A;  1P59 A;  2NOI A;  3CVT A;  4YOQ A;  1NKU A;  3FSP A;  1MPG A;  1XG7 A;  2NOL A;  4PII A;  1KG5 A;  1KG2 A;  1MUD A;  1P7M A;  1KEA A;  4E9E A;  1WEF A;  4B22 A;  3IHO A;  4E9H A;  1M3Q A;  4UOB A;  3KNT A;  2NOZ A;  2JG6 A;  4HSB A;  4OFA A;  1LWW A;  4AIA A;  1LWY A;  1WEG A;  4EVV A;  1LWV A;  3N0U A;  4UNF A;  3OGD A;  1YQL A;  1KG3 A;  1N3A A;  4AI4 A;  4AI5 A;  1FN7 A;  2OFK A;  1YQM A;  1KQJ A;  1ORN A;  1KG6 A;  4YPR A;  3OH9 A;  1RRQ A;  2JHJ A;  4EJZ A;  3KTU A;  3CVS A;  4EW4 A;  2OFI A;  5KN9 A;  3OH6 A;  5AN4 A;  2H56 A;  1VRL A;  4DK9 A;  4E9G A;  1PU8 A;  4EA4 A;  2ABK A;  2YG9 A;  2NOF A;  2NOB A;  4E9F A;  4B21 A;  3CWU A;  1RRS A;  2JHN A;  1XQO A;  1M3H A;  3F10 A;  3N5N X;  1PVS A;  1KG4 A;  2NOH A;  3CWA A;  3I0W A;  3S6I A;  5DPK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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