5KN9A

Muty n-terminal domain in complex with dna containing an intrahelical oxog:a base-pair
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
222
structure length
222
Chain Sequence
FPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRYETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
molecule keywords Adenine DNA glycosylase
publication title Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.
pubmed doi rcsb
source organism geobacillus stearothermophilus
total genus 80
structure length 222
sequence length 222
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2016-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 5kn9A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 5kn9A01
2YG8A 1XQPA 3S6IA 4UOBA 1XQOA 4E9FA 1LWWA 1LWYA 1NGNA 2JHJA 4YOQA 1KG2A 1VRLA 2I5WA 2H56A 4EA4A 1KG7A 2NOLA 3I0WA 1N39A 3IHOA 4YPRA 1FN7A 1KO9A 3FHGA 4HSBA 1ORPA 1M3HA 4E9EA 3G0QA 1RRSA 3FSPA 2NOZA 1EBMA 4OFAA 5KN9A 2XHIA 3CW7A 3KTUA 1RRQA 1M3QA 1KG3A 1MUDA 1KG5A 1PU6A 3KNTA 1N3CA 3N5NX 4OFHA 4EVVA 4YPHA 4B23A 1PU8A 3CVSA 1NKUA 3D4VA 4EW0A 3CWAA 3I0XA 4B24A 2NOIA 1YQKA 1MUNA 4E9HA 1PU7A 2NOHA 4UNFA 4AIAA 3OH9A 1LMZA 4EW4A 1YQRA 1KQJA 2NOEA 1YQMA 3CWSA 3F0ZA 3CWTA 1WEFA 1P7MA 3CWUA 1MPGA 4EJYA 1WEGA 4B21A 3N0UA 4AI4A 2JHNA 5DPKA 3F10A 3OH6A 1KEAA 1N3AA 1KG6A 4DK9A 2NOFA 4B22A 4AI5A 1PVSA 3OGDA 4EA5A 2ABKA 1HU0A 2YG9A 1MUYA 3CVTA 3FHFA 2JG6A 2NOBA 5KN8A 1ORNA 5CHZA 1DIZA 2OFIA 4PIIA 4EJZA 5AN4A 4OFEA 1P59A 3IH7A 1WEIA 1LWVA 1XG7A 2OFKA 4E9GA 1KG4A 1YQLA
chains in the Genus database with same CATH superfamily
2YG8A 1XQPA 3S6IA 4UOBA 1XQOA 4E9FA 1LWWA 1LWYA 4BDZA 4BE0A 1NGNA 3OYLA 2JHJA 4YOQA 1KG2A 1VRLA 2I5WA 2H56A 4EA4A 1KG7A 2NOLA 3I0WA 1N39A 4E7KA 3IHOA 4BACA 4YPRA 1FN7A 1KO9A 3FHGA 4E7LA 4HSBA 1ORPA 1M3HA 4BE1A 4BE2A 4E9EA 3G0QA 3OS0A 3FSPA 1RRSA 2NOZA 1EBMA 2JPSA 4OFAA 5KN9A 2XHIA 3OY9A 4E7IA 3CW7A 3OYDA 3KTUA 1RRQA 3OYNA 1M3QA 1KG3A 1MUDA 1KG5A 1PU6A 3L2RA 1YQLA 3KNTA 1N3CA 3N5NX 4OFHA 4EVVA 5FRMA 4YPHA 4B23A 2W04A 1PU8A 3CVSA 5FROA 1NKUA 3OYEA 3D4VA 4EW0A 3CWAA 3L2WA 3I0XA 4B24A 2NOIA 1YQKA 1MUNA 4E9HA 4E7HA 1PU7A 2NOHA 3OYCA 4UNFA 3R2XC 4AIAA 4ZTJA 3OH9A 1LMZA 4EW4A 3S3NA 1YQRA 1KQJA 2NOEA 1YQMA 3CWSA 3F0ZA 2W03A 3CWTA 1U84A 1WEFA 3L2VA 3S3OA 1P7MA 3OS2A 3CWUA 5FRNA 1MPGA 4EJYA 2V75A 1WEGA 3OYGA 3OYKA 4B21A 4IKFA 3N0UA 3VW4A 4NZGA 4AI4A 2JHNA 3OYIA 3NNQA 5DPKA 3F10A 3OYBA 3OH6A 1KEAA 4E7JA 1N3AA 4BDYA 1KG6A 4DK9A 2NOFA 4B22A 4AI5A 3S3MA 1PVSA 3OYHA 3OGDA 2ABKA 4EA5A 3OYMA 4ZTFA 1HU0A 3OS1A 2YG9A 1MUYA 3CVTA 3L2UA 3FHFA 2JG6A 3LCNA 2NOBA 5KN8A 3OYFA 1ORNA 5CHZA 1DIZA 2OFIA 4PIIA 4EJZA 5AN4A 4OFEA 3OYAA 1P59A 3IH7A 1WEIA 1LWVA 1XG7A 2OFKA 4E9GA 3OYJA 1KG4A 3L2QA
chains in the Genus database with same CATH topology
2YG8A 1XQPA 3S6IA 4UOBA 1XQOA 4E9FA 1LWWA 1LWYA 1NGNA 2JHJA 4YOQA 1KG2A 1VRLA 2I5WA 2H56A 4EA4A 1KG7A 2NOLA 3I0WA 1N39A 3IHOA 4YPRA 1FN7A 1KO9A 3FHGA 4HSBA 1ORPA 1M3HA 4E9EA 3G0QA 1RRSA 3FSPA 2NOZA 1EBMA 4OFAA 5KN9A 2XHIA 3CW7A 3KTUA 1RRQA 1M3QA 1KG3A 1MUDA 1KG5A 1PU6A 3KNTA 1N3CA 3N5NX 4OFHA 4EVVA 4YPHA 4B23A 1PU8A 3CVSA 1NKUA 3D4VA 4EW0A 3CWAA 3I0XA 4B24A 2NOIA 1YQKA 1MUNA 4E9HA 1PU7A 2NOHA 4UNFA 4AIAA 3OH9A 1LMZA 4EW4A 1YQRA 1KQJA 2NOEA 1YQMA 3CWSA 3F0ZA 3CWTA 1WEFA 1P7MA 3CWUA 1MPGA 4EJYA 1WEGA 4B21A 3N0UA 4AI4A 2JHNA 5DPKA 3F10A 3OH6A 1KEAA 1N3AA 1KG6A 4DK9A 2NOFA 4B22A 4AI5A 1PVSA 3OGDA 4EA5A 2ABKA 1HU0A 2YG9A 1MUYA 3CVTA 3FHFA 2JG6A 2NOBA 5KN8A 1ORNA 5CHZA 1DIZA 2OFIA 4PIIA 4EJZA 5AN4A 4OFEA 1P59A 3IH7A 1WEIA 1LWVA 1XG7A 2OFKA 4E9GA 1KG4A 1YQLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YG8 A;  1XQP A;  3S6I A;  4UOB A;  1XQO A;  4E9F A;  1LWW A;  1LWY A;  1NGN A;  2JHJ A;  4YOQ A;  1KG2 A;  1VRL A;  2I5W A;  2H56 A;  4EA4 A;  1KG7 A;  2NOL A;  3I0W A;  1N39 A;  3IHO A;  4YPR A;  1FN7 A;  1KO9 A;  3FHG A;  4HSB A;  1ORP A;  1M3H A;  4E9E A;  3G0Q A;  1RRS A;  3FSP A;  2NOZ A;  1EBM A;  4OFA A;  5KN9 A;  2XHI A;  3CW7 A;  3KTU A;  1RRQ A;  1M3Q A;  1KG3 A;  1MUD A;  1KG5 A;  1PU6 A;  3KNT A;  1N3C A;  3N5N X;  4OFH A;  4EVV A;  4YPH A;  4B23 A;  1PU8 A;  3CVS A;  1NKU A;  3D4V A;  4EW0 A;  3CWA A;  3I0X A;  4B24 A;  2NOI A;  1YQK A;  1MUN A;  4E9H A;  1PU7 A;  2NOH A;  4UNF A;  4AIA A;  3OH9 A;  1LMZ A;  4EW4 A;  1YQR A;  1KQJ A;  2NOE A;  1YQM A;  3CWS A;  3F0Z A;  3CWT A;  1WEF A;  1P7M A;  3CWU A;  1MPG A;  4EJY A;  1WEG A;  4B21 A;  3N0U A;  4AI4 A;  2JHN A;  5DPK A;  3F10 A;  3OH6 A;  1KEA A;  1N3A A;  1KG6 A;  4DK9 A;  2NOF A;  4B22 A;  4AI5 A;  1PVS A;  3OGD A;  4EA5 A;  2ABK A;  1HU0 A;  2YG9 A;  1MUY A;  3CVT A;  3FHF A;  2JG6 A;  2NOB A;  5KN8 A;  1ORN A;  5CHZ A;  1DIZ A;  2OFI A;  4PII A;  4EJZ A;  5AN4 A;  4OFE A;  1P59 A;  3IH7 A;  1WEI A;  1LWV A;  1XG7 A;  2OFK A;  4E9G A;  1KG4 A;  1YQL A; 
#chains in the Genus database with same CATH topology
 2YG8 A;  1XQP A;  3S6I A;  4UOB A;  1XQO A;  4E9F A;  1LWW A;  1LWY A;  4BDZ A;  4BE0 A;  1NGN A;  3OYL A;  2JHJ A;  4YOQ A;  1KG2 A;  1VRL A;  2I5W A;  2H56 A;  4EA4 A;  1KG7 A;  2NOL A;  3I0W A;  1N39 A;  4E7K A;  3IHO A;  4BAC A;  4YPR A;  1FN7 A;  1KO9 A;  3FHG A;  4E7L A;  4HSB A;  1ORP A;  1M3H A;  4BE1 A;  4BE2 A;  4E9E A;  3G0Q A;  3OS0 A;  3FSP A;  1RRS A;  2NOZ A;  1EBM A;  2JPS A;  4OFA A;  5KN9 A;  2XHI A;  3OY9 A;  4E7I A;  3CW7 A;  3OYD A;  3KTU A;  1RRQ A;  3OYN A;  1M3Q A;  1KG3 A;  1MUD A;  1KG5 A;  1PU6 A;  3L2R A;  1YQL A;  3KNT A;  1N3C A;  3N5N X;  4OFH A;  4EVV A;  5FRM A;  4YPH A;  4B23 A;  2W04 A;  1PU8 A;  3CVS A;  5FRO A;  1NKU A;  3OYE A;  3D4V A;  4EW0 A;  3CWA A;  3L2W A;  3I0X A;  4B24 A;  2NOI A;  1YQK A;  1MUN A;  4E9H A;  4E7H A;  1PU7 A;  2NOH A;  3OYC A;  4UNF A;  3R2X C;  4AIA A;  4ZTJ A;  3OH9 A;  1LMZ A;  4EW4 A;  3S3N A;  1YQR A;  1KQJ A;  2NOE A;  1YQM A;  3CWS A;  3F0Z A;  2W03 A;  3CWT A;  1U84 A;  1WEF A;  3L2V A;  3S3O A;  1P7M A;  3OS2 A;  3CWU A;  5FRN A;  1MPG A;  4EJY A;  2V75 A;  1WEG A;  3OYG A;  3OYK A;  4B21 A;  4IKF A;  3N0U A;  3VW4 A;  4NZG A;  4AI4 A;  2JHN A;  3OYI A;  3NNQ A;  5DPK A;  3F10 A;  3OYB A;  3OH6 A;  1KEA A;  4E7J A;  1N3A A;  4BDY A;  1KG6 A;  4DK9 A;  2NOF A;  4B22 A;  4AI5 A;  3S3M A;  1PVS A;  3OYH A;  3OGD A;  2ABK A;  4EA5 A;  3OYM A;  4ZTF A;  1HU0 A;  3OS1 A;  2YG9 A;  1MUY A;  3CVT A;  3L2U A;  3FHF A;  2JG6 A;  3LCN A;  2NOB A;  5KN8 A;  3OYF A;  1ORN A;  5CHZ A;  1DIZ A;  2OFI A;  4PII A;  4EJZ A;  5AN4 A;  4OFE A;  3OYA A;  1P59 A;  3IH7 A;  1WEI A;  1LWV A;  1XG7 A;  2OFK A;  4E9G A;  3OYJ A;  1KG4 A;  3L2Q A; 
#chains in the Genus database with same CATH homology
 2YG8 A;  1XQP A;  3S6I A;  4UOB A;  1XQO A;  4E9F A;  1LWW A;  1LWY A;  1NGN A;  2JHJ A;  4YOQ A;  1KG2 A;  1VRL A;  2I5W A;  2H56 A;  4EA4 A;  1KG7 A;  2NOL A;  3I0W A;  1N39 A;  3IHO A;  4YPR A;  1FN7 A;  1KO9 A;  3FHG A;  4HSB A;  1ORP A;  1M3H A;  4E9E A;  3G0Q A;  1RRS A;  3FSP A;  2NOZ A;  1EBM A;  4OFA A;  5KN9 A;  2XHI A;  3CW7 A;  3KTU A;  1RRQ A;  1M3Q A;  1KG3 A;  1MUD A;  1KG5 A;  1PU6 A;  3KNT A;  1N3C A;  3N5N X;  4OFH A;  4EVV A;  4YPH A;  4B23 A;  1PU8 A;  3CVS A;  1NKU A;  3D4V A;  4EW0 A;  3CWA A;  3I0X A;  4B24 A;  2NOI A;  1YQK A;  1MUN A;  4E9H A;  1PU7 A;  2NOH A;  4UNF A;  4AIA A;  3OH9 A;  1LMZ A;  4EW4 A;  1YQR A;  1KQJ A;  2NOE A;  1YQM A;  3CWS A;  3F0Z A;  3CWT A;  1WEF A;  1P7M A;  3CWU A;  1MPG A;  4EJY A;  1WEG A;  4B21 A;  3N0U A;  4AI4 A;  2JHN A;  5DPK A;  3F10 A;  3OH6 A;  1KEA A;  1N3A A;  1KG6 A;  4DK9 A;  2NOF A;  4B22 A;  4AI5 A;  1PVS A;  3OGD A;  4EA5 A;  2ABK A;  1HU0 A;  2YG9 A;  1MUY A;  3CVT A;  3FHF A;  2JG6 A;  2NOB A;  5KN8 A;  1ORN A;  5CHZ A;  1DIZ A;  2OFI A;  4PII A;  4EJZ A;  5AN4 A;  4OFE A;  1P59 A;  3IH7 A;  1WEI A;  1LWV A;  1XG7 A;  2OFK A;  4E9G A;  1KG4 A;  1YQL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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