1WEIA

Catalytic domain of muty from escherichia coli k20a mutant complexed to adenine
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
224
structure length
220
Chain Sequence
MQASQFSAQVLDWYDKYGRATLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARYAVSGWPGKKEVENKLWLSEQVTPAVGVERFNQAMMDLGAMCTRSKPKCLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 68
structure length 220
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2004-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1weiA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1weiA01
1KG6A 4YOQA 3OH9A 1FN7A 3D4VA 4OFEA 1LWWA 3CWTA 2NOBA 3CWUA 1NGNA 2YG8A 4UOBA 2NOEA 5DPKA 3CWSA 1MUNA 1M3QA 1PU6A 2OFIA 1WEFA 2H56A 1YQRA 2NOHA 3N5NX 1PU7A 3FHGA 1DIZA 3KTUA 4B22A 1HU0A 1LWVA 1PVSA 1XQOA 1ORPA 1XQPA 1LWYA 5CHZA 2OFKA 3I0XA 2NOIA 3OGDA 4EVVA 5KN8A 1M3HA 1KG2A 1KG7A 3CVSA 4B23A 2JHJA 4HSBA 3FSPA 4AIAA 2JHNA 3N0UA 1YQKA 1MUYA 1N39A 1NKUA 4AI4A 1P7MA 3KNTA 2JG6A 4PIIA 4B21A 1XG7A 4DK9A 3IHOA 3IH7A 4E9FA 4B24A 1VRLA 3S6IA 2ABKA 4OFAA 4EJYA 3CVTA 1EBMA 1PU8A 1KQJA 2NOLA 1N3CA 1WEGA 1ORNA 1RRQA 4E9HA 3G0QA 4UNFA 4YPRA 2YG9A 4E9EA 1KG3A 4YPHA 2XHIA 3CWAA 4EA5A 3I0WA 2NOFA 3OH6A 1KG4A 3CW7A 3F0ZA 1KO9A 1KG5A 1MPGA 4EA4A 1YQLA 4EW0A 1RRSA 1MUDA 5KN9A 5AN4A 1WEIA 4AI5A 4EJZA 3FHFA 1P59A 4E9GA 1YQMA 2NOZA 1LMZA 3F10A 4EW4A 1KEAA 2I5WA 4OFHA 1N3AA
chains in the Genus database with same CATH superfamily
1KG6A 4YOQA 3OY9A 3OH9A 1FN7A 3D4VA 4OFEA 1LWWA 3CWTA 2NOBA 3CWUA 1NGNA 2YG8A 4UOBA 4BE2A 3S3MA 2NOEA 5DPKA 3CWSA 3OYDA 4ZTFA 1MUNA 4IKFA 1M3QA 3OYMA 1PU6A 2OFIA 1WEFA 2H56A 1YQRA 2NOHA 3N5NX 4BACA 3OYBA 1PU7A 3FHGA 1DIZA 3L2RA 3KTUA 3OYCA 4B22A 1HU0A 1LWVA 1PVSA 1XQOA 1ORPA 1XQPA 1LWYA 5CHZA 2OFKA 3I0XA 2NOIA 3OGDA 4EVVA 5KN8A 4E7IA 1M3HA 1KG2A 1KG7A 3CVSA 3S3NA 4B23A 2JHJA 4HSBA 3OYGA 3FSPA 3LCNA 4AIAA 2JHNA 3N0UA 1YQKA 1MUYA 1N39A 4ZTJA 3S3OA 3OYKA 1NKUA 4AI4A 3R2XC 1P7MA 3KNTA 2JG6A 4PIIA 4B21A 3L2VA 4BDZA 4BE1A 4E7LA 1XG7A 4DK9A 3IHOA 3IH7A 4E9FA 4B24A 4E7HA 1VRLA 3S6IA 2ABKA 4OFAA 4EJYA 3CVTA 3L2UA 1EBMA 4E7KA 1PU8A 1KQJA 2NOLA 3OYEA 3L2WA 3L2QA 1WEGA 1N3CA 3OYAA 4E7JA 1ORNA 3OYIA 1RRQA 4E9HA 3G0QA 4UNFA 4NZGA 5FROA 1U84A 4YPRA 2YG9A 4E9EA 1KG3A 4BDYA 4YPHA 2XHIA 3OS0A 3CWAA 4EA5A 3I0WA 3OS2A 2V75A 2NOFA 3OH6A 3VW4A 1KG4A 4BE0A 3CW7A 3F0ZA 1KO9A 1KG5A 1MPGA 4EA4A 3OS1A 3OYNA 3NNQA 1YQLA 4EW0A 1RRSA 1MUDA 5KN9A 5AN4A 1WEIA 3OYJA 4AI5A 5FRNA 2JPSA 4EJZA 3FHFA 1P59A 3OYHA 4E9GA 1YQMA 2NOZA 2W03A 1LMZA 3F10A 3OYFA 4EW4A 1KEAA 2W04A 3OYLA 2I5WA 4OFHA 5FRMA 1N3AA
chains in the Genus database with same CATH topology
1KG6A 4YOQA 3OH9A 1FN7A 3D4VA 4OFEA 1LWWA 3CWTA 2NOBA 3CWUA 1NGNA 2YG8A 4UOBA 2NOEA 5DPKA 3CWSA 1MUNA 1M3QA 1PU6A 2OFIA 1WEFA 2H56A 1YQRA 2NOHA 3N5NX 1PU7A 3FHGA 1DIZA 3KTUA 4B22A 1HU0A 1LWVA 1PVSA 1XQOA 1ORPA 1XQPA 1LWYA 5CHZA 2OFKA 3I0XA 2NOIA 3OGDA 4EVVA 5KN8A 1M3HA 1KG2A 1KG7A 3CVSA 4B23A 2JHJA 4HSBA 3FSPA 4AIAA 2JHNA 3N0UA 1YQKA 1MUYA 1N39A 1NKUA 4AI4A 1P7MA 3KNTA 2JG6A 4PIIA 4B21A 1XG7A 4DK9A 3IHOA 3IH7A 4E9FA 4B24A 1VRLA 3S6IA 2ABKA 4OFAA 4EJYA 3CVTA 1EBMA 1PU8A 1KQJA 2NOLA 1N3CA 1WEGA 1ORNA 1RRQA 4E9HA 3G0QA 4UNFA 4YPRA 2YG9A 4E9EA 1KG3A 4YPHA 2XHIA 3CWAA 4EA5A 3I0WA 2NOFA 3OH6A 1KG4A 3CW7A 3F0ZA 1KO9A 1KG5A 1MPGA 4EA4A 1YQLA 4EW0A 1RRSA 1MUDA 5KN9A 5AN4A 1WEIA 4AI5A 4EJZA 3FHFA 1P59A 4E9GA 1YQMA 2NOZA 1LMZA 3F10A 4EW4A 1KEAA 2I5WA 4OFHA 1N3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KG6 A;  4YOQ A;  3OH9 A;  1FN7 A;  3D4V A;  4OFE A;  1LWW A;  3CWT A;  2NOB A;  3CWU A;  1NGN A;  2YG8 A;  4UOB A;  2NOE A;  5DPK A;  3CWS A;  1MUN A;  1M3Q A;  1PU6 A;  2OFI A;  1WEF A;  2H56 A;  1YQR A;  2NOH A;  3N5N X;  1PU7 A;  3FHG A;  1DIZ A;  3KTU A;  4B22 A;  1HU0 A;  1LWV A;  1PVS A;  1XQO A;  1ORP A;  1XQP A;  1LWY A;  5CHZ A;  2OFK A;  3I0X A;  2NOI A;  3OGD A;  4EVV A;  5KN8 A;  1M3H A;  1KG2 A;  1KG7 A;  3CVS A;  4B23 A;  2JHJ A;  4HSB A;  3FSP A;  4AIA A;  2JHN A;  3N0U A;  1YQK A;  1MUY A;  1N39 A;  1NKU A;  4AI4 A;  1P7M A;  3KNT A;  2JG6 A;  4PII A;  4B21 A;  1XG7 A;  4DK9 A;  3IHO A;  3IH7 A;  4E9F A;  4B24 A;  1VRL A;  3S6I A;  2ABK A;  4OFA A;  4EJY A;  3CVT A;  1EBM A;  1PU8 A;  1KQJ A;  2NOL A;  1N3C A;  1WEG A;  1ORN A;  1RRQ A;  4E9H A;  3G0Q A;  4UNF A;  4YPR A;  2YG9 A;  4E9E A;  1KG3 A;  4YPH A;  2XHI A;  3CWA A;  4EA5 A;  3I0W A;  2NOF A;  3OH6 A;  1KG4 A;  3CW7 A;  3F0Z A;  1KO9 A;  1KG5 A;  1MPG A;  4EA4 A;  1YQL A;  4EW0 A;  1RRS A;  1MUD A;  5KN9 A;  5AN4 A;  1WEI A;  4AI5 A;  4EJZ A;  3FHF A;  1P59 A;  4E9G A;  1YQM A;  2NOZ A;  1LMZ A;  3F10 A;  4EW4 A;  1KEA A;  2I5W A;  4OFH A;  1N3A A; 
#chains in the Genus database with same CATH topology
 1KG6 A;  4YOQ A;  3OY9 A;  3OH9 A;  1FN7 A;  3D4V A;  4OFE A;  1LWW A;  3CWT A;  2NOB A;  3CWU A;  1NGN A;  2YG8 A;  4UOB A;  4BE2 A;  3S3M A;  2NOE A;  5DPK A;  3CWS A;  3OYD A;  4ZTF A;  1MUN A;  4IKF A;  1M3Q A;  3OYM A;  1PU6 A;  2OFI A;  1WEF A;  2H56 A;  1YQR A;  2NOH A;  3N5N X;  4BAC A;  3OYB A;  1PU7 A;  3FHG A;  1DIZ A;  3L2R A;  3KTU A;  3OYC A;  4B22 A;  1HU0 A;  1LWV A;  1PVS A;  1XQO A;  1ORP A;  1XQP A;  1LWY A;  5CHZ A;  2OFK A;  3I0X A;  2NOI A;  3OGD A;  4EVV A;  5KN8 A;  4E7I A;  1M3H A;  1KG2 A;  1KG7 A;  3CVS A;  3S3N A;  4B23 A;  2JHJ A;  4HSB A;  3OYG A;  3FSP A;  3LCN A;  4AIA A;  2JHN A;  3N0U A;  1YQK A;  1MUY A;  1N39 A;  4ZTJ A;  3S3O A;  3OYK A;  1NKU A;  4AI4 A;  3R2X C;  1P7M A;  3KNT A;  2JG6 A;  4PII A;  4B21 A;  3L2V A;  4BDZ A;  4BE1 A;  4E7L A;  1XG7 A;  4DK9 A;  3IHO A;  3IH7 A;  4E9F A;  4B24 A;  4E7H A;  1VRL A;  3S6I A;  2ABK A;  4OFA A;  4EJY A;  3CVT A;  3L2U A;  1EBM A;  4E7K A;  1PU8 A;  1KQJ A;  2NOL A;  3OYE A;  3L2W A;  3L2Q A;  1WEG A;  1N3C A;  3OYA A;  4E7J A;  1ORN A;  3OYI A;  1RRQ A;  4E9H A;  3G0Q A;  4UNF A;  4NZG A;  5FRO A;  1U84 A;  4YPR A;  2YG9 A;  4E9E A;  1KG3 A;  4BDY A;  4YPH A;  2XHI A;  3OS0 A;  3CWA A;  4EA5 A;  3I0W A;  3OS2 A;  2V75 A;  2NOF A;  3OH6 A;  3VW4 A;  1KG4 A;  4BE0 A;  3CW7 A;  3F0Z A;  1KO9 A;  1KG5 A;  1MPG A;  4EA4 A;  3OS1 A;  3OYN A;  3NNQ A;  1YQL A;  4EW0 A;  1RRS A;  1MUD A;  5KN9 A;  5AN4 A;  1WEI A;  3OYJ A;  4AI5 A;  5FRN A;  2JPS A;  4EJZ A;  3FHF A;  1P59 A;  3OYH A;  4E9G A;  1YQM A;  2NOZ A;  2W03 A;  1LMZ A;  3F10 A;  3OYF A;  4EW4 A;  1KEA A;  2W04 A;  3OYL A;  2I5W A;  4OFH A;  5FRM A;  1N3A A; 
#chains in the Genus database with same CATH homology
 1KG6 A;  4YOQ A;  3OH9 A;  1FN7 A;  3D4V A;  4OFE A;  1LWW A;  3CWT A;  2NOB A;  3CWU A;  1NGN A;  2YG8 A;  4UOB A;  2NOE A;  5DPK A;  3CWS A;  1MUN A;  1M3Q A;  1PU6 A;  2OFI A;  1WEF A;  2H56 A;  1YQR A;  2NOH A;  3N5N X;  1PU7 A;  3FHG A;  1DIZ A;  3KTU A;  4B22 A;  1HU0 A;  1LWV A;  1PVS A;  1XQO A;  1ORP A;  1XQP A;  1LWY A;  5CHZ A;  2OFK A;  3I0X A;  2NOI A;  3OGD A;  4EVV A;  5KN8 A;  1M3H A;  1KG2 A;  1KG7 A;  3CVS A;  4B23 A;  2JHJ A;  4HSB A;  3FSP A;  4AIA A;  2JHN A;  3N0U A;  1YQK A;  1MUY A;  1N39 A;  1NKU A;  4AI4 A;  1P7M A;  3KNT A;  2JG6 A;  4PII A;  4B21 A;  1XG7 A;  4DK9 A;  3IHO A;  3IH7 A;  4E9F A;  4B24 A;  1VRL A;  3S6I A;  2ABK A;  4OFA A;  4EJY A;  3CVT A;  1EBM A;  1PU8 A;  1KQJ A;  2NOL A;  1N3C A;  1WEG A;  1ORN A;  1RRQ A;  4E9H A;  3G0Q A;  4UNF A;  4YPR A;  2YG9 A;  4E9E A;  1KG3 A;  4YPH A;  2XHI A;  3CWA A;  4EA5 A;  3I0W A;  2NOF A;  3OH6 A;  1KG4 A;  3CW7 A;  3F0Z A;  1KO9 A;  1KG5 A;  1MPG A;  4EA4 A;  1YQL A;  4EW0 A;  1RRS A;  1MUD A;  5KN9 A;  5AN4 A;  1WEI A;  4AI5 A;  4EJZ A;  3FHF A;  1P59 A;  4E9G A;  1YQM A;  2NOZ A;  1LMZ A;  3F10 A;  4EW4 A;  1KEA A;  2I5W A;  4OFH A;  1N3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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