1WEIA

Catalytic domain of muty from escherichia coli k20a mutant complexed to adenine
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
224
structure length
220
Chain Sequence
MQASQFSAQVLDWYDKYGRATLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARYAVSGWPGKKEVENKLWLSEQVTPAVGVERFNQAMMDLGAMCTRSKPKCLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 68
structure length 220
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2004-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1weiA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1weiA01
1M3QA 2NOIA 1LWVA 2NOZA 4YPHA 4B23A 2NOFA 1YQLA 1LWWA 2NOEA 4OFAA 1MUNA 1MUYA 2JHNA 2XHIA 3FHFA 1XQOA 1XQPA 1NGNA 4HSBA 1YQRA 3FHGA 2NOLA 4EVVA 4EW4A 1YQMA 1KG2A 3KNTA 1NKUA 3KTUA 2NOBA 4UNFA 1WEFA 5KN9A 1EBMA 3CWUA 1KQJA 4E9EA 3IH7A 1MUDA 5CHZA 1P7MA 3CWTA 1KO9A 1M3HA 1RRSA 4B22A 3OH6A 3CVSA 4AIAA 4YOQA 3OGDA 1KG7A 1LMZA 4B24A 2JHJA 3N5NX 2JG6A 5AN4A 4EA5A 3F0ZA 3S6IA 3N0UA 4UOBA 3IHOA 5KN8A 2I5WA 1DIZA 4AI4A 4E9HA 1YQKA 4EJYA 2NOHA 3CVTA 2H56A 1WEIA 4B21A 1MPGA 1PU6A 4PIIA 1P59A 1N39A 4YPRA 3CWSA 4EA4A 4E9GA 3D4VA 1HU0A 1N3AA 2OFIA 4OFEA 3CWAA 1PU7A 2YG8A 1N3CA 5DPKA 1PU8A 4EJZA 1WEGA 1KG3A 1KG5A 4EW0A 1XG7A 3FSPA 1FN7A 2ABKA 4E9FA 1PVSA 4AI5A 3OH9A 2YG9A 4OFHA 3I0WA 2OFKA 4DK9A 1RRQA 1ORNA 1KG4A 3I0XA 1KG6A 1ORPA 1VRLA 3CW7A 1KEAA 3G0QA 1LWYA 3F10A
chains in the Genus database with same CATH superfamily
1M3QA 4E7KA 2NOIA 1LWVA 4E7LA 2NOZA 4ZTFA 4YPHA 4B23A 2NOFA 1YQLA 1LWWA 2NOEA 3VW4A 4OFAA 1MUNA 1MUYA 3L2RA 2JHNA 2XHIA 4E7JA 3S3OA 3R2XC 3S3MA 3FHFA 1XQOA 1XQPA 1NGNA 3OYKA 4HSBA 3S3NA 1YQRA 3FHGA 4IKFA 3NNQA 2NOLA 3L2UA 3L2VA 4EVVA 4EW4A 2JPSA 1YQMA 1KG2A 3KNTA 1NKUA 3KTUA 2NOBA 4UNFA 1WEFA 5KN9A 4E7HA 4ZTJA 1EBMA 3CWUA 4E7IA 1KQJA 3OS2A 4E9EA 3IH7A 1MUDA 5CHZA 1P7MA 3CWTA 1KO9A 1M3HA 3OYFA 5FROA 1RRSA 4B22A 4BDYA 3OH6A 3OYAA 3CVSA 5FRNA 4AIAA 4YOQA 3OGDA 1KG7A 1LMZA 4B24A 2JHJA 3N5NX 2JG6A 5AN4A 4EA5A 3OYCA 3F0ZA 3S6IA 3N0UA 2W04A 4UOBA 3LCNA 3IHOA 5KN8A 3L2WA 2I5WA 1DIZA 4AI4A 4BE0A 4E9HA 1YQKA 4EJYA 2NOHA 3L2QA 2W03A 2H56A 3CVTA 1WEIA 4B21A 2V75A 3OYEA 1MPGA 1PU6A 4PIIA 1P59A 3OYDA 1N39A 4YPRA 3CWSA 4EA4A 4BE1A 4E9GA 3D4VA 4BDZA 1U84A 1HU0A 3OYBA 1N3AA 2OFIA 3OYHA 4OFEA 3CWAA 1PU7A 3OY9A 4NZGA 3OYIA 2YG8A 1N3CA 5DPKA 1PU8A 4EJZA 1WEGA 1KG3A 1KG5A 3OYLA 4EW0A 1XG7A 3OS0A 3FSPA 1FN7A 3OYJA 2ABKA 3OYNA 4E9FA 1PVSA 4AI5A 3OH9A 2YG9A 4OFHA 3I0WA 2OFKA 4BACA 4DK9A 1RRQA 4BE2A 1ORNA 1KG4A 3I0XA 1KG6A 3OS1A 5FRMA 1ORPA 3OYMA 1VRLA 3OYGA 3CW7A 1KEAA 3G0QA 1LWYA 3F10A
chains in the Genus database with same CATH topology
1M3QA 2NOIA 1LWVA 2NOZA 4YPHA 4B23A 2NOFA 1YQLA 1LWWA 2NOEA 4OFAA 1MUNA 1MUYA 2JHNA 2XHIA 3FHFA 1XQOA 1XQPA 1NGNA 4HSBA 1YQRA 3FHGA 2NOLA 4EVVA 4EW4A 1YQMA 1KG2A 3KNTA 1NKUA 3KTUA 2NOBA 4UNFA 1WEFA 5KN9A 1EBMA 3CWUA 1KQJA 4E9EA 3IH7A 1MUDA 5CHZA 1P7MA 3CWTA 1KO9A 1M3HA 1RRSA 4B22A 3OH6A 3CVSA 4AIAA 4YOQA 3OGDA 1KG7A 1LMZA 4B24A 2JHJA 3N5NX 2JG6A 5AN4A 4EA5A 3F0ZA 3S6IA 3N0UA 4UOBA 3IHOA 5KN8A 2I5WA 1DIZA 4AI4A 4E9HA 1YQKA 4EJYA 2NOHA 3CVTA 2H56A 1WEIA 4B21A 1MPGA 1PU6A 4PIIA 1P59A 1N39A 4YPRA 3CWSA 4EA4A 4E9GA 3D4VA 1HU0A 1N3AA 2OFIA 4OFEA 3CWAA 1PU7A 2YG8A 1N3CA 5DPKA 1PU8A 4EJZA 1WEGA 1KG3A 1KG5A 4EW0A 1XG7A 3FSPA 1FN7A 2ABKA 4E9FA 1PVSA 4AI5A 3OH9A 2YG9A 4OFHA 3I0WA 2OFKA 4DK9A 1RRQA 1ORNA 1KG4A 3I0XA 1KG6A 1ORPA 1VRLA 3CW7A 1KEAA 3G0QA 1LWYA 3F10A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M3Q A;  2NOI A;  1LWV A;  2NOZ A;  4YPH A;  4B23 A;  2NOF A;  1YQL A;  1LWW A;  2NOE A;  4OFA A;  1MUN A;  1MUY A;  2JHN A;  2XHI A;  3FHF A;  1XQO A;  1XQP A;  1NGN A;  4HSB A;  1YQR A;  3FHG A;  2NOL A;  4EVV A;  4EW4 A;  1YQM A;  1KG2 A;  3KNT A;  1NKU A;  3KTU A;  2NOB A;  4UNF A;  1WEF A;  5KN9 A;  1EBM A;  3CWU A;  1KQJ A;  4E9E A;  3IH7 A;  1MUD A;  5CHZ A;  1P7M A;  3CWT A;  1KO9 A;  1M3H A;  1RRS A;  4B22 A;  3OH6 A;  3CVS A;  4AIA A;  4YOQ A;  3OGD A;  1KG7 A;  1LMZ A;  4B24 A;  2JHJ A;  3N5N X;  2JG6 A;  5AN4 A;  4EA5 A;  3F0Z A;  3S6I A;  3N0U A;  4UOB A;  3IHO A;  5KN8 A;  2I5W A;  1DIZ A;  4AI4 A;  4E9H A;  1YQK A;  4EJY A;  2NOH A;  3CVT A;  2H56 A;  1WEI A;  4B21 A;  1MPG A;  1PU6 A;  4PII A;  1P59 A;  1N39 A;  4YPR A;  3CWS A;  4EA4 A;  4E9G A;  3D4V A;  1HU0 A;  1N3A A;  2OFI A;  4OFE A;  3CWA A;  1PU7 A;  2YG8 A;  1N3C A;  5DPK A;  1PU8 A;  4EJZ A;  1WEG A;  1KG3 A;  1KG5 A;  4EW0 A;  1XG7 A;  3FSP A;  1FN7 A;  2ABK A;  4E9F A;  1PVS A;  4AI5 A;  3OH9 A;  2YG9 A;  4OFH A;  3I0W A;  2OFK A;  4DK9 A;  1RRQ A;  1ORN A;  1KG4 A;  3I0X A;  1KG6 A;  1ORP A;  1VRL A;  3CW7 A;  1KEA A;  3G0Q A;  1LWY A;  3F10 A; 
#chains in the Genus database with same CATH topology
 1M3Q A;  4E7K A;  2NOI A;  1LWV A;  4E7L A;  2NOZ A;  4ZTF A;  4YPH A;  4B23 A;  2NOF A;  1YQL A;  1LWW A;  2NOE A;  3VW4 A;  4OFA A;  1MUN A;  1MUY A;  3L2R A;  2JHN A;  2XHI A;  4E7J A;  3S3O A;  3R2X C;  3S3M A;  3FHF A;  1XQO A;  1XQP A;  1NGN A;  3OYK A;  4HSB A;  3S3N A;  1YQR A;  3FHG A;  4IKF A;  3NNQ A;  2NOL A;  3L2U A;  3L2V A;  4EVV A;  4EW4 A;  2JPS A;  1YQM A;  1KG2 A;  3KNT A;  1NKU A;  3KTU A;  2NOB A;  4UNF A;  1WEF A;  5KN9 A;  4E7H A;  4ZTJ A;  1EBM A;  3CWU A;  4E7I A;  1KQJ A;  3OS2 A;  4E9E A;  3IH7 A;  1MUD A;  5CHZ A;  1P7M A;  3CWT A;  1KO9 A;  1M3H A;  3OYF A;  5FRO A;  1RRS A;  4B22 A;  4BDY A;  3OH6 A;  3OYA A;  3CVS A;  5FRN A;  4AIA A;  4YOQ A;  3OGD A;  1KG7 A;  1LMZ A;  4B24 A;  2JHJ A;  3N5N X;  2JG6 A;  5AN4 A;  4EA5 A;  3OYC A;  3F0Z A;  3S6I A;  3N0U A;  2W04 A;  4UOB A;  3LCN A;  3IHO A;  5KN8 A;  3L2W A;  2I5W A;  1DIZ A;  4AI4 A;  4BE0 A;  4E9H A;  1YQK A;  4EJY A;  2NOH A;  3L2Q A;  2W03 A;  2H56 A;  3CVT A;  1WEI A;  4B21 A;  2V75 A;  3OYE A;  1MPG A;  1PU6 A;  4PII A;  1P59 A;  3OYD A;  1N39 A;  4YPR A;  3CWS A;  4EA4 A;  4BE1 A;  4E9G A;  3D4V A;  4BDZ A;  1U84 A;  1HU0 A;  3OYB A;  1N3A A;  2OFI A;  3OYH A;  4OFE A;  3CWA A;  1PU7 A;  3OY9 A;  4NZG A;  3OYI A;  2YG8 A;  1N3C A;  5DPK A;  1PU8 A;  4EJZ A;  1WEG A;  1KG3 A;  1KG5 A;  3OYL A;  4EW0 A;  1XG7 A;  3OS0 A;  3FSP A;  1FN7 A;  3OYJ A;  2ABK A;  3OYN A;  4E9F A;  1PVS A;  4AI5 A;  3OH9 A;  2YG9 A;  4OFH A;  3I0W A;  2OFK A;  4BAC A;  4DK9 A;  1RRQ A;  4BE2 A;  1ORN A;  1KG4 A;  3I0X A;  1KG6 A;  3OS1 A;  5FRM A;  1ORP A;  3OYM A;  1VRL A;  3OYG A;  3CW7 A;  1KEA A;  3G0Q A;  1LWY A;  3F10 A; 
#chains in the Genus database with same CATH homology
 1M3Q A;  2NOI A;  1LWV A;  2NOZ A;  4YPH A;  4B23 A;  2NOF A;  1YQL A;  1LWW A;  2NOE A;  4OFA A;  1MUN A;  1MUY A;  2JHN A;  2XHI A;  3FHF A;  1XQO A;  1XQP A;  1NGN A;  4HSB A;  1YQR A;  3FHG A;  2NOL A;  4EVV A;  4EW4 A;  1YQM A;  1KG2 A;  3KNT A;  1NKU A;  3KTU A;  2NOB A;  4UNF A;  1WEF A;  5KN9 A;  1EBM A;  3CWU A;  1KQJ A;  4E9E A;  3IH7 A;  1MUD A;  5CHZ A;  1P7M A;  3CWT A;  1KO9 A;  1M3H A;  1RRS A;  4B22 A;  3OH6 A;  3CVS A;  4AIA A;  4YOQ A;  3OGD A;  1KG7 A;  1LMZ A;  4B24 A;  2JHJ A;  3N5N X;  2JG6 A;  5AN4 A;  4EA5 A;  3F0Z A;  3S6I A;  3N0U A;  4UOB A;  3IHO A;  5KN8 A;  2I5W A;  1DIZ A;  4AI4 A;  4E9H A;  1YQK A;  4EJY A;  2NOH A;  3CVT A;  2H56 A;  1WEI A;  4B21 A;  1MPG A;  1PU6 A;  4PII A;  1P59 A;  1N39 A;  4YPR A;  3CWS A;  4EA4 A;  4E9G A;  3D4V A;  1HU0 A;  1N3A A;  2OFI A;  4OFE A;  3CWA A;  1PU7 A;  2YG8 A;  1N3C A;  5DPK A;  1PU8 A;  4EJZ A;  1WEG A;  1KG3 A;  1KG5 A;  4EW0 A;  1XG7 A;  3FSP A;  1FN7 A;  2ABK A;  4E9F A;  1PVS A;  4AI5 A;  3OH9 A;  2YG9 A;  4OFH A;  3I0W A;  2OFK A;  4DK9 A;  1RRQ A;  1ORN A;  1KG4 A;  3I0X A;  1KG6 A;  1ORP A;  1VRL A;  3CW7 A;  1KEA A;  3G0Q A;  1LWY A;  3F10 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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