1KQJA

Crystal structure of a mutant of muty catalytic domain
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKHSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-SPECIFIC ADENINE GLYCOSYLASE
publication title Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 75
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2002-01-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kqjA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kqjA01
4PIIA 1XG7A 1RRSA 1VRLA 1LMZA 4B24A 1KQJA 3KNTA 1LWWA 3N5NX 4OFHA 1ORNA 1RRQA 4OFEA 2OFKA 5KN8A 2H56A 3OGDA 1KEAA 2XHIA 1KG7A 4EJZA 2NOIA 1NGNA 1MUDA 1KG3A 1NKUA 1DIZA 4EA5A 1LWVA 2JHNA 4E9FA 2YG8A 3FHGA 1LWYA 3CWUA 1M3QA 2I5WA 1MUYA 1WEFA 3OH9A 3IH7A 1WEGA 1WEIA 1XQOA 3KTUA 4E9EA 1KG2A 3I0XA 1MUNA 5AN4A 4YOQA 3G0QA 3FHFA 1PU8A 4EVVA 2NOBA 3S6IA 5KN9A 1YQRA 4EJYA 1YQLA 1KO9A 3CW7A 1P7MA 3IHOA 3CWAA 3N0UA 4UNFA 1YQMA 5CHZA 1XQPA 1HU0A 4EA4A 1YQKA 2NOZA 1EBMA 3CWSA 2NOEA 3CVTA 1PU7A 3I0WA 4HSBA 1N3CA 1M3HA 1KG6A 2NOHA 3CVSA 2NOLA 3FSPA 3D4VA 1FN7A 1PVSA 4OFAA 1P59A 1KG4A 4E9HA 4UOBA 4DK9A 2JHJA 4B23A 1N3AA 4YPHA 4E9GA 4B22A 4AIAA 1N39A 3F0ZA 4AI4A 4AI5A 1ORPA 4EW0A 2OFIA 4B21A 3OH6A 1KG5A 5DPKA 2NOFA 2JG6A 3F10A 1MPGA 2ABKA 2YG9A 4EW4A 3CWTA 4YPRA 1PU6A
chains in the Genus database with same CATH superfamily
4PIIA 1XG7A 1RRSA 1VRLA 4BE1A 3OS0A 1LMZA 4B24A 1KQJA 3KNTA 1LWWA 3N5NX 4OFHA 1ORNA 3OYAA 1RRQA 4OFEA 4BACA 3OYDA 2OFKA 5KN8A 2H56A 3OGDA 1KEAA 2XHIA 1KG7A 3LCNA 4EJZA 3OYHA 4E7KA 2NOIA 1NGNA 1MUDA 1KG3A 3OYIA 4E7HA 4BDZA 1NKUA 3S3MA 4ZTFA 1DIZA 4EA5A 1LWVA 2JHNA 4E9FA 2YG8A 3FHGA 4BDYA 1LWYA 3CWUA 1M3QA 2I5WA 1MUYA 1WEFA 3OS1A 3OH9A 3IH7A 4BE0A 1WEGA 1WEIA 1XQOA 3OYLA 2W03A 3NNQA 3OYBA 3KTUA 4E9EA 1KG2A 3I0XA 1MUNA 5AN4A 4ZTJA 4YOQA 3G0QA 3FHFA 3L2UA 4IKFA 2V75A 1PU8A 4EVVA 3OYJA 2NOBA 3S6IA 5KN9A 1YQRA 4EJYA 1YQLA 1KO9A 3CW7A 1P7MA 3IHOA 3VW4A 3CWAA 3N0UA 4UNFA 1YQMA 3R2XC 5CHZA 1XQPA 1HU0A 4EA4A 4NZGA 1YQKA 2NOZA 3L2WA 1EBMA 3CWSA 2NOEA 3OYCA 3L2RA 3CVTA 4E7LA 4BE2A 1PU7A 3I0WA 4HSBA 1N3CA 1M3HA 2JPSA 4E7JA 1KG6A 3S3NA 2NOHA 3CVSA 2NOLA 3FSPA 3D4VA 1FN7A 5FRMA 1PVSA 4OFAA 1P59A 1KG4A 4E9HA 4UOBA 4DK9A 2JHJA 1U84A 3L2QA 4B23A 1N3AA 4YPHA 4E9GA 4B22A 4AIAA 1N39A 3F0ZA 4AI4A 2W04A 4AI5A 3OYMA 3OY9A 1ORPA 5FRNA 4EW0A 3OYKA 3S3OA 4B21A 2OFIA 3OH6A 1KG5A 3OYEA 5FROA 3OYNA 3OS2A 5DPKA 2JG6A 2NOFA 3F10A 3OYGA 3L2VA 1MPGA 3OYFA 2ABKA 2YG9A 4EW4A 4E7IA 3CWTA 4YPRA 1PU6A
chains in the Genus database with same CATH topology
4PIIA 1XG7A 1RRSA 1VRLA 1LMZA 4B24A 1KQJA 3KNTA 1LWWA 3N5NX 4OFHA 1ORNA 1RRQA 4OFEA 2OFKA 5KN8A 2H56A 3OGDA 1KEAA 2XHIA 1KG7A 4EJZA 2NOIA 1NGNA 1MUDA 1KG3A 1NKUA 1DIZA 4EA5A 1LWVA 2JHNA 4E9FA 2YG8A 3FHGA 1LWYA 3CWUA 1M3QA 2I5WA 1MUYA 1WEFA 3OH9A 3IH7A 1WEGA 1WEIA 1XQOA 3KTUA 4E9EA 1KG2A 3I0XA 1MUNA 5AN4A 4YOQA 3G0QA 3FHFA 1PU8A 4EVVA 2NOBA 3S6IA 5KN9A 1YQRA 4EJYA 1YQLA 1KO9A 3CW7A 1P7MA 3IHOA 3CWAA 3N0UA 4UNFA 1YQMA 5CHZA 1XQPA 1HU0A 4EA4A 1YQKA 2NOZA 1EBMA 3CWSA 2NOEA 3CVTA 1PU7A 3I0WA 4HSBA 1N3CA 1M3HA 1KG6A 2NOHA 3CVSA 2NOLA 3FSPA 3D4VA 1FN7A 1PVSA 4OFAA 1P59A 1KG4A 4E9HA 4UOBA 4DK9A 2JHJA 4B23A 1N3AA 4YPHA 4E9GA 4B22A 4AIAA 1N39A 3F0ZA 4AI4A 4AI5A 1ORPA 4EW0A 2OFIA 4B21A 3OH6A 1KG5A 5DPKA 2NOFA 2JG6A 3F10A 1MPGA 2ABKA 2YG9A 4EW4A 3CWTA 4YPRA 1PU6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PII A;  1XG7 A;  1RRS A;  1VRL A;  1LMZ A;  4B24 A;  1KQJ A;  3KNT A;  1LWW A;  3N5N X;  4OFH A;  1ORN A;  1RRQ A;  4OFE A;  2OFK A;  5KN8 A;  2H56 A;  3OGD A;  1KEA A;  2XHI A;  1KG7 A;  4EJZ A;  2NOI A;  1NGN A;  1MUD A;  1KG3 A;  1NKU A;  1DIZ A;  4EA5 A;  1LWV A;  2JHN A;  4E9F A;  2YG8 A;  3FHG A;  1LWY A;  3CWU A;  1M3Q A;  2I5W A;  1MUY A;  1WEF A;  3OH9 A;  3IH7 A;  1WEG A;  1WEI A;  1XQO A;  3KTU A;  4E9E A;  1KG2 A;  3I0X A;  1MUN A;  5AN4 A;  4YOQ A;  3G0Q A;  3FHF A;  1PU8 A;  4EVV A;  2NOB A;  3S6I A;  5KN9 A;  1YQR A;  4EJY A;  1YQL A;  1KO9 A;  3CW7 A;  1P7M A;  3IHO A;  3CWA A;  3N0U A;  4UNF A;  1YQM A;  5CHZ A;  1XQP A;  1HU0 A;  4EA4 A;  1YQK A;  2NOZ A;  1EBM A;  3CWS A;  2NOE A;  3CVT A;  1PU7 A;  3I0W A;  4HSB A;  1N3C A;  1M3H A;  1KG6 A;  2NOH A;  3CVS A;  2NOL A;  3FSP A;  3D4V A;  1FN7 A;  1PVS A;  4OFA A;  1P59 A;  1KG4 A;  4E9H A;  4UOB A;  4DK9 A;  2JHJ A;  4B23 A;  1N3A A;  4YPH A;  4E9G A;  4B22 A;  4AIA A;  1N39 A;  3F0Z A;  4AI4 A;  4AI5 A;  1ORP A;  4EW0 A;  2OFI A;  4B21 A;  3OH6 A;  1KG5 A;  5DPK A;  2NOF A;  2JG6 A;  3F10 A;  1MPG A;  2ABK A;  2YG9 A;  4EW4 A;  3CWT A;  4YPR A;  1PU6 A; 
#chains in the Genus database with same CATH topology
 4PII A;  1XG7 A;  1RRS A;  1VRL A;  4BE1 A;  3OS0 A;  1LMZ A;  4B24 A;  1KQJ A;  3KNT A;  1LWW A;  3N5N X;  4OFH A;  1ORN A;  3OYA A;  1RRQ A;  4OFE A;  4BAC A;  3OYD A;  2OFK A;  5KN8 A;  2H56 A;  3OGD A;  1KEA A;  2XHI A;  1KG7 A;  3LCN A;  4EJZ A;  3OYH A;  4E7K A;  2NOI A;  1NGN A;  1MUD A;  1KG3 A;  3OYI A;  4E7H A;  4BDZ A;  1NKU A;  3S3M A;  4ZTF A;  1DIZ A;  4EA5 A;  1LWV A;  2JHN A;  4E9F A;  2YG8 A;  3FHG A;  4BDY A;  1LWY A;  3CWU A;  1M3Q A;  2I5W A;  1MUY A;  1WEF A;  3OS1 A;  3OH9 A;  3IH7 A;  4BE0 A;  1WEG A;  1WEI A;  1XQO A;  3OYL A;  2W03 A;  3NNQ A;  3OYB A;  3KTU A;  4E9E A;  1KG2 A;  3I0X A;  1MUN A;  5AN4 A;  4ZTJ A;  4YOQ A;  3G0Q A;  3FHF A;  3L2U A;  4IKF A;  2V75 A;  1PU8 A;  4EVV A;  3OYJ A;  2NOB A;  3S6I A;  5KN9 A;  1YQR A;  4EJY A;  1YQL A;  1KO9 A;  3CW7 A;  1P7M A;  3IHO A;  3VW4 A;  3CWA A;  3N0U A;  4UNF A;  1YQM A;  3R2X C;  5CHZ A;  1XQP A;  1HU0 A;  4EA4 A;  4NZG A;  1YQK A;  2NOZ A;  3L2W A;  1EBM A;  3CWS A;  2NOE A;  3OYC A;  3L2R A;  3CVT A;  4E7L A;  4BE2 A;  1PU7 A;  3I0W A;  4HSB A;  1N3C A;  1M3H A;  2JPS A;  4E7J A;  1KG6 A;  3S3N A;  2NOH A;  3CVS A;  2NOL A;  3FSP A;  3D4V A;  1FN7 A;  5FRM A;  1PVS A;  4OFA A;  1P59 A;  1KG4 A;  4E9H A;  4UOB A;  4DK9 A;  2JHJ A;  1U84 A;  3L2Q A;  4B23 A;  1N3A A;  4YPH A;  4E9G A;  4B22 A;  4AIA A;  1N39 A;  3F0Z A;  4AI4 A;  2W04 A;  4AI5 A;  3OYM A;  3OY9 A;  1ORP A;  5FRN A;  4EW0 A;  3OYK A;  3S3O A;  4B21 A;  2OFI A;  3OH6 A;  1KG5 A;  3OYE A;  5FRO A;  3OYN A;  3OS2 A;  5DPK A;  2JG6 A;  2NOF A;  3F10 A;  3OYG A;  3L2V A;  1MPG A;  3OYF A;  2ABK A;  2YG9 A;  4EW4 A;  4E7I A;  3CWT A;  4YPR A;  1PU6 A; 
#chains in the Genus database with same CATH homology
 4PII A;  1XG7 A;  1RRS A;  1VRL A;  1LMZ A;  4B24 A;  1KQJ A;  3KNT A;  1LWW A;  3N5N X;  4OFH A;  1ORN A;  1RRQ A;  4OFE A;  2OFK A;  5KN8 A;  2H56 A;  3OGD A;  1KEA A;  2XHI A;  1KG7 A;  4EJZ A;  2NOI A;  1NGN A;  1MUD A;  1KG3 A;  1NKU A;  1DIZ A;  4EA5 A;  1LWV A;  2JHN A;  4E9F A;  2YG8 A;  3FHG A;  1LWY A;  3CWU A;  1M3Q A;  2I5W A;  1MUY A;  1WEF A;  3OH9 A;  3IH7 A;  1WEG A;  1WEI A;  1XQO A;  3KTU A;  4E9E A;  1KG2 A;  3I0X A;  1MUN A;  5AN4 A;  4YOQ A;  3G0Q A;  3FHF A;  1PU8 A;  4EVV A;  2NOB A;  3S6I A;  5KN9 A;  1YQR A;  4EJY A;  1YQL A;  1KO9 A;  3CW7 A;  1P7M A;  3IHO A;  3CWA A;  3N0U A;  4UNF A;  1YQM A;  5CHZ A;  1XQP A;  1HU0 A;  4EA4 A;  1YQK A;  2NOZ A;  1EBM A;  3CWS A;  2NOE A;  3CVT A;  1PU7 A;  3I0W A;  4HSB A;  1N3C A;  1M3H A;  1KG6 A;  2NOH A;  3CVS A;  2NOL A;  3FSP A;  3D4V A;  1FN7 A;  1PVS A;  4OFA A;  1P59 A;  1KG4 A;  4E9H A;  4UOB A;  4DK9 A;  2JHJ A;  4B23 A;  1N3A A;  4YPH A;  4E9G A;  4B22 A;  4AIA A;  1N39 A;  3F0Z A;  4AI4 A;  4AI5 A;  1ORP A;  4EW0 A;  2OFI A;  4B21 A;  3OH6 A;  1KG5 A;  5DPK A;  2NOF A;  2JG6 A;  3F10 A;  1MPG A;  2ABK A;  2YG9 A;  4EW4 A;  3CWT A;  4YPR A;  1PU6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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