1MUYA

Catalytic domain of muty from escherichia coli
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADENINE GLYCOSYLASE
publication title MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily.
pubmed doi rcsb
molecule tags Dna repair
total genus 75
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 1998-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1muyA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1muyA01
1P59A 2JHNA 1YQLA 1VRLA 4B24A 1WEIA 2NOBA 4YOQA 3CWSA 1KG4A 4YPHA 3G0QA 1MPGA 1KG6A 4OFEA 3OGDA 1P7MA 3D4VA 4E9HA 1KEAA 3KTUA 3I0XA 2YG8A 1XG7A 1RRSA 3N5NX 5KN8A 3F0ZA 3CWUA 3S6IA 4EA5A 4E9EA 1PU6A 5KN9A 1XQPA 1M3QA 1YQMA 2NOFA 3FSPA 4OFHA 1NKUA 1YQRA 1XQOA 1WEFA 4AI5A 2NOLA 2H56A 4AI4A 3KNTA 2NOHA 1LMZA 3CWAA 1KG3A 2JG6A 1PU8A 1MUYA 5AN4A 1LWWA 2NOIA 2OFKA 2OFIA 4HSBA 1RRQA 1DIZA 3N0UA 1ORNA 4EW4A 1KO9A 4B21A 2XHIA 3CVTA 3CVSA 4YPRA 2NOZA 3CWTA 1ORPA 4EA4A 1KQJA 4B23A 4DK9A 1M3HA 1KG7A 2NOEA 1NGNA 1PU7A 2JHJA 3F10A 5CHZA 4EJYA 1MUNA 4EVVA 2I5WA 2ABKA 1N3AA 3FHFA 4E9FA 4OFAA 3OH9A 4AIAA 3IH7A 3I0WA 4B22A 2YG9A 1KG2A 1N39A 1LWVA 1MUDA 1KG5A 4E9GA 3CW7A 1N3CA 1WEGA 4UOBA 3IHOA 3OH6A 3FHGA 5DPKA 1HU0A 1YQKA 4EW0A 4PIIA 1LWYA 1EBMA 1FN7A 1PVSA 4UNFA 4EJZA
chains in the Genus database with same CATH superfamily
1P59A 3S3NA 2JHNA 1YQLA 3OS0A 1VRLA 4B24A 1WEIA 2NOBA 4YOQA 3CWSA 1KG4A 3VW4A 4YPHA 3G0QA 1MPGA 1KG6A 4OFEA 3OGDA 1P7MA 3D4VA 3S3OA 3OYDA 4E9HA 1KEAA 3KTUA 3I0XA 2YG8A 1XG7A 1RRSA 3OYFA 1U84A 2V75A 3N5NX 3OYAA 4BE2A 5KN8A 3F0ZA 3CWUA 3S6IA 3OYNA 4EA5A 4E7KA 4E9EA 1PU6A 4E7LA 5KN9A 1XQPA 1M3QA 1YQMA 2NOFA 3OYBA 3R2XC 4OFHA 1NKUA 3FSPA 4BE0A 1YQRA 2W04A 1XQOA 4BDZA 1WEFA 4AI5A 2NOLA 2H56A 4BE1A 3OYHA 4NZGA 4AI4A 3KNTA 2NOHA 1LMZA 3CWAA 1KG3A 2JG6A 5FRNA 1PU8A 1MUYA 5AN4A 1LWWA 2NOIA 4IKFA 2OFKA 2W03A 2OFIA 4HSBA 1RRQA 3OYLA 1DIZA 3N0UA 1ORNA 4EW4A 3L2WA 5FROA 1KO9A 4B21A 2XHIA 3NNQA 3CVTA 3CVSA 3OS1A 4YPRA 2NOZA 3CWTA 1ORPA 4ZTFA 3LCNA 4EA4A 4E7JA 1KQJA 4B23A 4DK9A 1M3HA 3OYEA 1KG7A 4E7IA 2NOEA 1NGNA 1PU7A 2JHJA 3OY9A 3F10A 3S3MA 5CHZA 3OYCA 4EJYA 4BACA 1MUNA 4EVVA 2I5WA 5FRMA 2ABKA 1N3AA 3FHFA 3L2RA 4E9FA 3OYMA 4OFAA 3OH9A 4AIAA 3IH7A 3OYJA 3I0WA 2JPSA 4ZTJA 4B22A 3OYGA 2YG9A 1KG2A 3L2VA 1N39A 1LWVA 1MUDA 1KG5A 4E9GA 3CW7A 4BDYA 1N3CA 4E7HA 1WEGA 4UOBA 3IHOA 3OH6A 3FHGA 5DPKA 1HU0A 1YQKA 3OYKA 4EW0A 4PIIA 1LWYA 1EBMA 1FN7A 1PVSA 4UNFA 3L2UA 3OS2A 3OYIA 3L2QA 4EJZA
chains in the Genus database with same CATH topology
1P59A 2JHNA 1YQLA 1VRLA 4B24A 1WEIA 2NOBA 4YOQA 3CWSA 1KG4A 4YPHA 3G0QA 1MPGA 1KG6A 4OFEA 3OGDA 1P7MA 3D4VA 4E9HA 1KEAA 3KTUA 3I0XA 2YG8A 1XG7A 1RRSA 3N5NX 5KN8A 3F0ZA 3CWUA 3S6IA 4EA5A 4E9EA 1PU6A 5KN9A 1XQPA 1M3QA 1YQMA 2NOFA 3FSPA 4OFHA 1NKUA 1YQRA 1XQOA 1WEFA 4AI5A 2NOLA 2H56A 4AI4A 3KNTA 2NOHA 1LMZA 3CWAA 1KG3A 2JG6A 1PU8A 1MUYA 5AN4A 1LWWA 2NOIA 2OFKA 2OFIA 4HSBA 1RRQA 1DIZA 3N0UA 1ORNA 4EW4A 1KO9A 4B21A 2XHIA 3CVTA 3CVSA 4YPRA 2NOZA 3CWTA 1ORPA 4EA4A 1KQJA 4B23A 4DK9A 1M3HA 1KG7A 2NOEA 1NGNA 1PU7A 2JHJA 3F10A 5CHZA 4EJYA 1MUNA 4EVVA 2I5WA 2ABKA 1N3AA 3FHFA 4E9FA 4OFAA 3OH9A 4AIAA 3IH7A 3I0WA 4B22A 2YG9A 1KG2A 1N39A 1LWVA 1MUDA 1KG5A 4E9GA 3CW7A 1N3CA 1WEGA 4UOBA 3IHOA 3OH6A 3FHGA 5DPKA 1HU0A 1YQKA 4EW0A 4PIIA 1LWYA 1EBMA 1FN7A 1PVSA 4UNFA 4EJZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P59 A;  2JHN A;  1YQL A;  1VRL A;  4B24 A;  1WEI A;  2NOB A;  4YOQ A;  3CWS A;  1KG4 A;  4YPH A;  3G0Q A;  1MPG A;  1KG6 A;  4OFE A;  3OGD A;  1P7M A;  3D4V A;  4E9H A;  1KEA A;  3KTU A;  3I0X A;  2YG8 A;  1XG7 A;  1RRS A;  3N5N X;  5KN8 A;  3F0Z A;  3CWU A;  3S6I A;  4EA5 A;  4E9E A;  1PU6 A;  5KN9 A;  1XQP A;  1M3Q A;  1YQM A;  2NOF A;  3FSP A;  4OFH A;  1NKU A;  1YQR A;  1XQO A;  1WEF A;  4AI5 A;  2NOL A;  2H56 A;  4AI4 A;  3KNT A;  2NOH A;  1LMZ A;  3CWA A;  1KG3 A;  2JG6 A;  1PU8 A;  1MUY A;  5AN4 A;  1LWW A;  2NOI A;  2OFK A;  2OFI A;  4HSB A;  1RRQ A;  1DIZ A;  3N0U A;  1ORN A;  4EW4 A;  1KO9 A;  4B21 A;  2XHI A;  3CVT A;  3CVS A;  4YPR A;  2NOZ A;  3CWT A;  1ORP A;  4EA4 A;  1KQJ A;  4B23 A;  4DK9 A;  1M3H A;  1KG7 A;  2NOE A;  1NGN A;  1PU7 A;  2JHJ A;  3F10 A;  5CHZ A;  4EJY A;  1MUN A;  4EVV A;  2I5W A;  2ABK A;  1N3A A;  3FHF A;  4E9F A;  4OFA A;  3OH9 A;  4AIA A;  3IH7 A;  3I0W A;  4B22 A;  2YG9 A;  1KG2 A;  1N39 A;  1LWV A;  1MUD A;  1KG5 A;  4E9G A;  3CW7 A;  1N3C A;  1WEG A;  4UOB A;  3IHO A;  3OH6 A;  3FHG A;  5DPK A;  1HU0 A;  1YQK A;  4EW0 A;  4PII A;  1LWY A;  1EBM A;  1FN7 A;  1PVS A;  4UNF A;  4EJZ A; 
#chains in the Genus database with same CATH topology
 1P59 A;  3S3N A;  2JHN A;  1YQL A;  3OS0 A;  1VRL A;  4B24 A;  1WEI A;  2NOB A;  4YOQ A;  3CWS A;  1KG4 A;  3VW4 A;  4YPH A;  3G0Q A;  1MPG A;  1KG6 A;  4OFE A;  3OGD A;  1P7M A;  3D4V A;  3S3O A;  3OYD A;  4E9H A;  1KEA A;  3KTU A;  3I0X A;  2YG8 A;  1XG7 A;  1RRS A;  3OYF A;  1U84 A;  2V75 A;  3N5N X;  3OYA A;  4BE2 A;  5KN8 A;  3F0Z A;  3CWU A;  3S6I A;  3OYN A;  4EA5 A;  4E7K A;  4E9E A;  1PU6 A;  4E7L A;  5KN9 A;  1XQP A;  1M3Q A;  1YQM A;  2NOF A;  3OYB A;  3R2X C;  4OFH A;  1NKU A;  3FSP A;  4BE0 A;  1YQR A;  2W04 A;  1XQO A;  4BDZ A;  1WEF A;  4AI5 A;  2NOL A;  2H56 A;  4BE1 A;  3OYH A;  4NZG A;  4AI4 A;  3KNT A;  2NOH A;  1LMZ A;  3CWA A;  1KG3 A;  2JG6 A;  5FRN A;  1PU8 A;  1MUY A;  5AN4 A;  1LWW A;  2NOI A;  4IKF A;  2OFK A;  2W03 A;  2OFI A;  4HSB A;  1RRQ A;  3OYL A;  1DIZ A;  3N0U A;  1ORN A;  4EW4 A;  3L2W A;  5FRO A;  1KO9 A;  4B21 A;  2XHI A;  3NNQ A;  3CVT A;  3CVS A;  3OS1 A;  4YPR A;  2NOZ A;  3CWT A;  1ORP A;  4ZTF A;  3LCN A;  4EA4 A;  4E7J A;  1KQJ A;  4B23 A;  4DK9 A;  1M3H A;  3OYE A;  1KG7 A;  4E7I A;  2NOE A;  1NGN A;  1PU7 A;  2JHJ A;  3OY9 A;  3F10 A;  3S3M A;  5CHZ A;  3OYC A;  4EJY A;  4BAC A;  1MUN A;  4EVV A;  2I5W A;  5FRM A;  2ABK A;  1N3A A;  3FHF A;  3L2R A;  4E9F A;  3OYM A;  4OFA A;  3OH9 A;  4AIA A;  3IH7 A;  3OYJ A;  3I0W A;  2JPS A;  4ZTJ A;  4B22 A;  3OYG A;  2YG9 A;  1KG2 A;  3L2V A;  1N39 A;  1LWV A;  1MUD A;  1KG5 A;  4E9G A;  3CW7 A;  4BDY A;  1N3C A;  4E7H A;  1WEG A;  4UOB A;  3IHO A;  3OH6 A;  3FHG A;  5DPK A;  1HU0 A;  1YQK A;  3OYK A;  4EW0 A;  4PII A;  1LWY A;  1EBM A;  1FN7 A;  1PVS A;  4UNF A;  3L2U A;  3OS2 A;  3OYI A;  3L2Q A;  4EJZ A; 
#chains in the Genus database with same CATH homology
 1P59 A;  2JHN A;  1YQL A;  1VRL A;  4B24 A;  1WEI A;  2NOB A;  4YOQ A;  3CWS A;  1KG4 A;  4YPH A;  3G0Q A;  1MPG A;  1KG6 A;  4OFE A;  3OGD A;  1P7M A;  3D4V A;  4E9H A;  1KEA A;  3KTU A;  3I0X A;  2YG8 A;  1XG7 A;  1RRS A;  3N5N X;  5KN8 A;  3F0Z A;  3CWU A;  3S6I A;  4EA5 A;  4E9E A;  1PU6 A;  5KN9 A;  1XQP A;  1M3Q A;  1YQM A;  2NOF A;  3FSP A;  4OFH A;  1NKU A;  1YQR A;  1XQO A;  1WEF A;  4AI5 A;  2NOL A;  2H56 A;  4AI4 A;  3KNT A;  2NOH A;  1LMZ A;  3CWA A;  1KG3 A;  2JG6 A;  1PU8 A;  1MUY A;  5AN4 A;  1LWW A;  2NOI A;  2OFK A;  2OFI A;  4HSB A;  1RRQ A;  1DIZ A;  3N0U A;  1ORN A;  4EW4 A;  1KO9 A;  4B21 A;  2XHI A;  3CVT A;  3CVS A;  4YPR A;  2NOZ A;  3CWT A;  1ORP A;  4EA4 A;  1KQJ A;  4B23 A;  4DK9 A;  1M3H A;  1KG7 A;  2NOE A;  1NGN A;  1PU7 A;  2JHJ A;  3F10 A;  5CHZ A;  4EJY A;  1MUN A;  4EVV A;  2I5W A;  2ABK A;  1N3A A;  3FHF A;  4E9F A;  4OFA A;  3OH9 A;  4AIA A;  3IH7 A;  3I0W A;  4B22 A;  2YG9 A;  1KG2 A;  1N39 A;  1LWV A;  1MUD A;  1KG5 A;  4E9G A;  3CW7 A;  1N3C A;  1WEG A;  4UOB A;  3IHO A;  3OH6 A;  3FHG A;  5DPK A;  1HU0 A;  1YQK A;  4EW0 A;  4PII A;  1LWY A;  1EBM A;  1FN7 A;  1PVS A;  4UNF A;  4EJZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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