1MUYA

Catalytic domain of muty from escherichia coli
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna repair
molecule keywords ADENINE GLYCOSYLASE
publication title MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily.
pubmed doi rcsb
total genus 75
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 1998-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1muyA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1muyA01
4EJYA 2NOFA 1KO9A 1YQKA 1N39A 1NGNA 3IH7A 1KG7A 2OFKA 1XQOA 3S6IA 3OGDA 3I0WA 5KN8A 2YG9A 1FN7A 4E9EA 1P59A 3F10A 2NOLA 1PU7A 4EJZA 5AN4A 1LWYA 4B21A 3CW7A 4B24A 2OFIA 1MUYA 2JG6A 3G0QA 2XHIA 1ORPA 1P7MA 3OH6A 4EA4A 3N0UA 4E9FA 4AI5A 1N3AA 2YG8A 1KG4A 4UNFA 4B22A 1YQRA 4EA5A 1KG5A 2NOHA 1NKUA 3KTUA 4HSBA 1DIZA 1M3QA 3FHFA 4OFAA 1PU8A 1KG6A 4PIIA 1ORNA 1KG3A 4EW4A 4DK9A 1MPGA 4EW0A 3IHOA 1KEAA 3CVSA 3FSPA 4AIAA 1WEFA 4YPRA 2NOIA 4OFEA 4EVVA 2NOBA 1MUNA 3D4VA 1KQJA 4YPHA 1PU6A 1WEGA 1XQPA 2NOZA 3I0XA 3CVTA 4B23A 1M3HA 2NOEA 1EBMA 2JHJA 1YQMA 1XG7A 1LWWA 1LMZA 1RRQA 1VRLA 1N3CA 3CWUA 3CWSA 1LWVA 2H56A 1RRSA 2JHNA 4UOBA 3KNTA 2I5WA 3CWTA 1MUDA 1PVSA 1WEIA 1KG2A 3CWAA 1HU0A 3OH9A 3N5NX 4E9GA 5CHZA 3FHGA 3F0ZA 5KN9A 2ABKA 1YQLA 4E9HA 4OFHA 5DPKA 4AI4A 4YOQA
chains in the Genus database with same CATH superfamily
4EJYA 2NOFA 1KO9A 1YQKA 1N39A 1NGNA 3IH7A 3OYJA 3OYFA 1KG7A 1U84A 2OFKA 3OYEA 1XQOA 3OS0A 3S6IA 4E7HA 3OGDA 3I0WA 5KN8A 2YG9A 1FN7A 4E9EA 3OS1A 1P59A 4BACA 3F10A 2NOLA 1PU7A 4EJZA 5AN4A 3OYAA 1LWYA 4B21A 3CW7A 4B24A 2OFIA 1MUYA 2JG6A 3G0QA 2XHIA 1ORPA 2W04A 1P7MA 3OH6A 4EA4A 3N0UA 4E9FA 4AI5A 1N3AA 2YG8A 1KG4A 3OYBA 4E7KA 4UNFA 4B22A 3OYCA 4EA5A 1YQRA 1KG5A 2NOHA 4ZTFA 1NKUA 3KTUA 4HSBA 1DIZA 3OYHA 3L2VA 1M3QA 3FHFA 3OYGA 4BE0A 4OFAA 1PU8A 3L2WA 1KG6A 2V75A 4PIIA 1ORNA 1KG3A 4EW4A 4DK9A 3OY9A 1MPGA 4EW0A 3S3MA 3IHOA 1KEAA 3CVSA 3FSPA 4AIAA 5FROA 1WEFA 4YPRA 2NOIA 3S3OA 4OFEA 4EVVA 2NOBA 3OYDA 1MUNA 3OYIA 3L2QA 3D4VA 1KQJA 3LCNA 4YPHA 2W03A 3NNQA 1PU6A 1WEGA 1XQPA 2NOZA 3I0XA 3CVTA 4B23A 4BDYA 1M3HA 2NOEA 1EBMA 4NZGA 2JHJA 1YQMA 1XG7A 1LWWA 1LMZA 3OYNA 3OYMA 4E7JA 5FRMA 1RRQA 1VRLA 1N3CA 3CWUA 3CWSA 1LWVA 2H56A 4BE2A 1RRSA 2JHNA 3OYKA 4UOBA 3L2RA 3KNTA 2I5WA 3S3NA 3CWTA 3L2UA 1MUDA 1PVSA 1WEIA 1KG2A 3OS2A 3CWAA 4ZTJA 1HU0A 3OH9A 3N5NX 4E9GA 5CHZA 3FHGA 3F0ZA 3VW4A 5KN9A 4BE1A 2ABKA 1YQLA 4E7LA 3OYLA 4E9HA 5FRNA 4BDZA 4OFHA 4IKFA 3R2XC 5DPKA 2JPSA 4AI4A 4YOQA 4E7IA
chains in the Genus database with same CATH topology
4EJYA 2NOFA 1KO9A 1YQKA 1N39A 1NGNA 3IH7A 1KG7A 2OFKA 1XQOA 3S6IA 3OGDA 3I0WA 5KN8A 2YG9A 1FN7A 4E9EA 1P59A 3F10A 2NOLA 1PU7A 4EJZA 5AN4A 1LWYA 4B21A 3CW7A 4B24A 2OFIA 1MUYA 2JG6A 3G0QA 2XHIA 1ORPA 1P7MA 3OH6A 4EA4A 3N0UA 4E9FA 4AI5A 1N3AA 2YG8A 1KG4A 4UNFA 4B22A 1YQRA 4EA5A 1KG5A 2NOHA 1NKUA 3KTUA 4HSBA 1DIZA 1M3QA 3FHFA 4OFAA 1PU8A 1KG6A 4PIIA 1ORNA 1KG3A 4EW4A 4DK9A 1MPGA 4EW0A 3IHOA 1KEAA 3CVSA 3FSPA 4AIAA 1WEFA 4YPRA 2NOIA 4OFEA 4EVVA 2NOBA 1MUNA 3D4VA 1KQJA 4YPHA 1PU6A 1WEGA 1XQPA 2NOZA 3I0XA 3CVTA 4B23A 1M3HA 2NOEA 1EBMA 2JHJA 1YQMA 1XG7A 1LWWA 1LMZA 1RRQA 1VRLA 1N3CA 3CWUA 3CWSA 1LWVA 2H56A 1RRSA 2JHNA 4UOBA 3KNTA 2I5WA 3CWTA 1MUDA 1PVSA 1WEIA 1KG2A 3CWAA 1HU0A 3OH9A 3N5NX 4E9GA 5CHZA 3FHGA 3F0ZA 5KN9A 2ABKA 1YQLA 4E9HA 4OFHA 5DPKA 4AI4A 4YOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EJY A;  2NOF A;  1KO9 A;  1YQK A;  1N39 A;  1NGN A;  3IH7 A;  1KG7 A;  2OFK A;  1XQO A;  3S6I A;  3OGD A;  3I0W A;  5KN8 A;  2YG9 A;  1FN7 A;  4E9E A;  1P59 A;  3F10 A;  2NOL A;  1PU7 A;  4EJZ A;  5AN4 A;  1LWY A;  4B21 A;  3CW7 A;  4B24 A;  2OFI A;  1MUY A;  2JG6 A;  3G0Q A;  2XHI A;  1ORP A;  1P7M A;  3OH6 A;  4EA4 A;  3N0U A;  4E9F A;  4AI5 A;  1N3A A;  2YG8 A;  1KG4 A;  4UNF A;  4B22 A;  1YQR A;  4EA5 A;  1KG5 A;  2NOH A;  1NKU A;  3KTU A;  4HSB A;  1DIZ A;  1M3Q A;  3FHF A;  4OFA A;  1PU8 A;  1KG6 A;  4PII A;  1ORN A;  1KG3 A;  4EW4 A;  4DK9 A;  1MPG A;  4EW0 A;  3IHO A;  1KEA A;  3CVS A;  3FSP A;  4AIA A;  1WEF A;  4YPR A;  2NOI A;  4OFE A;  4EVV A;  2NOB A;  1MUN A;  3D4V A;  1KQJ A;  4YPH A;  1PU6 A;  1WEG A;  1XQP A;  2NOZ A;  3I0X A;  3CVT A;  4B23 A;  1M3H A;  2NOE A;  1EBM A;  2JHJ A;  1YQM A;  1XG7 A;  1LWW A;  1LMZ A;  1RRQ A;  1VRL A;  1N3C A;  3CWU A;  3CWS A;  1LWV A;  2H56 A;  1RRS A;  2JHN A;  4UOB A;  3KNT A;  2I5W A;  3CWT A;  1MUD A;  1PVS A;  1WEI A;  1KG2 A;  3CWA A;  1HU0 A;  3OH9 A;  3N5N X;  4E9G A;  5CHZ A;  3FHG A;  3F0Z A;  5KN9 A;  2ABK A;  1YQL A;  4E9H A;  4OFH A;  5DPK A;  4AI4 A;  4YOQ A; 
#chains in the Genus database with same CATH topology
 4EJY A;  2NOF A;  1KO9 A;  1YQK A;  1N39 A;  1NGN A;  3IH7 A;  3OYJ A;  3OYF A;  1KG7 A;  1U84 A;  2OFK A;  3OYE A;  1XQO A;  3OS0 A;  3S6I A;  4E7H A;  3OGD A;  3I0W A;  5KN8 A;  2YG9 A;  1FN7 A;  4E9E A;  3OS1 A;  1P59 A;  4BAC A;  3F10 A;  2NOL A;  1PU7 A;  4EJZ A;  5AN4 A;  3OYA A;  1LWY A;  4B21 A;  3CW7 A;  4B24 A;  2OFI A;  1MUY A;  2JG6 A;  3G0Q A;  2XHI A;  1ORP A;  2W04 A;  1P7M A;  3OH6 A;  4EA4 A;  3N0U A;  4E9F A;  4AI5 A;  1N3A A;  2YG8 A;  1KG4 A;  3OYB A;  4E7K A;  4UNF A;  4B22 A;  3OYC A;  4EA5 A;  1YQR A;  1KG5 A;  2NOH A;  4ZTF A;  1NKU A;  3KTU A;  4HSB A;  1DIZ A;  3OYH A;  3L2V A;  1M3Q A;  3FHF A;  3OYG A;  4BE0 A;  4OFA A;  1PU8 A;  3L2W A;  1KG6 A;  2V75 A;  4PII A;  1ORN A;  1KG3 A;  4EW4 A;  4DK9 A;  3OY9 A;  1MPG A;  4EW0 A;  3S3M A;  3IHO A;  1KEA A;  3CVS A;  3FSP A;  4AIA A;  5FRO A;  1WEF A;  4YPR A;  2NOI A;  3S3O A;  4OFE A;  4EVV A;  2NOB A;  3OYD A;  1MUN A;  3OYI A;  3L2Q A;  3D4V A;  1KQJ A;  3LCN A;  4YPH A;  2W03 A;  3NNQ A;  1PU6 A;  1WEG A;  1XQP A;  2NOZ A;  3I0X A;  3CVT A;  4B23 A;  4BDY A;  1M3H A;  2NOE A;  1EBM A;  4NZG A;  2JHJ A;  1YQM A;  1XG7 A;  1LWW A;  1LMZ A;  3OYN A;  3OYM A;  4E7J A;  5FRM A;  1RRQ A;  1VRL A;  1N3C A;  3CWU A;  3CWS A;  1LWV A;  2H56 A;  4BE2 A;  1RRS A;  2JHN A;  3OYK A;  4UOB A;  3L2R A;  3KNT A;  2I5W A;  3S3N A;  3CWT A;  3L2U A;  1MUD A;  1PVS A;  1WEI A;  1KG2 A;  3OS2 A;  3CWA A;  4ZTJ A;  1HU0 A;  3OH9 A;  3N5N X;  4E9G A;  5CHZ A;  3FHG A;  3F0Z A;  3VW4 A;  5KN9 A;  4BE1 A;  2ABK A;  1YQL A;  4E7L A;  3OYL A;  4E9H A;  5FRN A;  4BDZ A;  4OFH A;  4IKF A;  3R2X C;  5DPK A;  2JPS A;  4AI4 A;  4YOQ A;  4E7I A; 
#chains in the Genus database with same CATH homology
 4EJY A;  2NOF A;  1KO9 A;  1YQK A;  1N39 A;  1NGN A;  3IH7 A;  1KG7 A;  2OFK A;  1XQO A;  3S6I A;  3OGD A;  3I0W A;  5KN8 A;  2YG9 A;  1FN7 A;  4E9E A;  1P59 A;  3F10 A;  2NOL A;  1PU7 A;  4EJZ A;  5AN4 A;  1LWY A;  4B21 A;  3CW7 A;  4B24 A;  2OFI A;  1MUY A;  2JG6 A;  3G0Q A;  2XHI A;  1ORP A;  1P7M A;  3OH6 A;  4EA4 A;  3N0U A;  4E9F A;  4AI5 A;  1N3A A;  2YG8 A;  1KG4 A;  4UNF A;  4B22 A;  1YQR A;  4EA5 A;  1KG5 A;  2NOH A;  1NKU A;  3KTU A;  4HSB A;  1DIZ A;  1M3Q A;  3FHF A;  4OFA A;  1PU8 A;  1KG6 A;  4PII A;  1ORN A;  1KG3 A;  4EW4 A;  4DK9 A;  1MPG A;  4EW0 A;  3IHO A;  1KEA A;  3CVS A;  3FSP A;  4AIA A;  1WEF A;  4YPR A;  2NOI A;  4OFE A;  4EVV A;  2NOB A;  1MUN A;  3D4V A;  1KQJ A;  4YPH A;  1PU6 A;  1WEG A;  1XQP A;  2NOZ A;  3I0X A;  3CVT A;  4B23 A;  1M3H A;  2NOE A;  1EBM A;  2JHJ A;  1YQM A;  1XG7 A;  1LWW A;  1LMZ A;  1RRQ A;  1VRL A;  1N3C A;  3CWU A;  3CWS A;  1LWV A;  2H56 A;  1RRS A;  2JHN A;  4UOB A;  3KNT A;  2I5W A;  3CWT A;  1MUD A;  1PVS A;  1WEI A;  1KG2 A;  3CWA A;  1HU0 A;  3OH9 A;  3N5N X;  4E9G A;  5CHZ A;  3FHG A;  3F0Z A;  5KN9 A;  2ABK A;  1YQL A;  4E9H A;  4OFH A;  5DPK A;  4AI4 A;  4YOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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