1MUYA

Catalytic domain of muty from escherichia coli
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADENINE GLYCOSYLASE
publication title MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily.
pubmed doi rcsb
molecule tags Dna repair
total genus 75
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 1998-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1muyA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1muyA01
1LWYA 2XHIA 4HSBA 1YQRA 1DIZA 3CWUA 4B23A 3D4VA 2ABKA 1PU7A 3F0ZA 4EVVA 1M3QA 1LWWA 4UNFA 2NOBA 2NOEA 1YQKA 1M3HA 3OH6A 1MUDA 4E9EA 4EA5A 1YQLA 4AI4A 4EW4A 3CWSA 4EJZA 1KG6A 1PU6A 3CWAA 1WEIA 1KO9A 2YG8A 4AIAA 3G0QA 4B22A 1KG7A 3KTUA 3OH9A 3I0WA 4E9FA 1N3CA 4OFEA 4OFHA 1KG3A 1FN7A 3FSPA 3CWTA 1PU8A 3FHFA 1KEAA 3IH7A 4EA4A 1KG2A 2JHNA 1RRQA 1MPGA 3KNTA 1ORPA 1ORNA 3F10A 1KQJA 1N3AA 4EJYA 3CVSA 1KG4A 1YQMA 2OFIA 1VRLA 3OGDA 5KN9A 4OFAA 1P7MA 5KN8A 1KG5A 1PVSA 1LWVA 1HU0A 4B24A 3IHOA 4B21A 1EBMA 2NOFA 2YG9A 4AI5A 1P59A 4E9GA 1WEGA 1XQOA 1XQPA 3CW7A 5AN4A 2NOHA 3FHGA 2H56A 4UOBA 1RRSA 4PIIA 5DPKA 5CHZA 1XG7A 3I0XA 1N39A 4E9HA 1MUYA 1MUNA 2OFKA 2JG6A 2I5WA 3N0UA 2NOZA 4EW0A 4YOQA 1WEFA 3S6IA 4DK9A 1NKUA 3CVTA 1LMZA 1NGNA 3N5NX 2NOIA 2JHJA 2NOLA 4YPRA 4YPHA
chains in the Genus database with same CATH superfamily
4BE2A 1LWYA 2XHIA 4HSBA 1YQRA 1DIZA 3CWUA 4B23A 4BDZA 5FROA 3D4VA 2ABKA 1PU7A 3F0ZA 3S3MA 4EVVA 1M3QA 4BE1A 1LWWA 3OYAA 4UNFA 2NOBA 2NOEA 1YQKA 3OS2A 1M3HA 3OH6A 4BDYA 1MUDA 4E9EA 4EA5A 1YQLA 4AI4A 4EW4A 3CWSA 4EJZA 3LCNA 1KG6A 4E7IA 1PU6A 4BACA 3CWAA 1WEIA 1KO9A 2YG8A 4AIAA 3G0QA 4BE0A 3S3OA 4B22A 3NNQA 3R2XC 1KG7A 3KTUA 3OH9A 3I0WA 3L2UA 4E9FA 1N3CA 3OYFA 4OFEA 4OFHA 1KG3A 1FN7A 3FSPA 3CWTA 1PU8A 3FHFA 3VW4A 1KEAA 3IH7A 4EA4A 1KG2A 1U84A 2JHNA 2JPSA 1RRQA 1MPGA 3KNTA 1ORPA 1ORNA 3OYJA 4NZGA 3OYDA 3F10A 3OYBA 3L2QA 1KQJA 1N3AA 4EJYA 3L2VA 3CVSA 1KG4A 1YQMA 4E7HA 2OFIA 1VRLA 3OGDA 4E7KA 5KN9A 4OFAA 1P7MA 5KN8A 1KG5A 3OS1A 1PVSA 4ZTJA 1HU0A 1LWVA 4B24A 3IHOA 3OYCA 4B21A 1EBMA 2NOFA 2YG9A 4ZTFA 5FRNA 2V75A 4AI5A 3OYIA 2W04A 4E9GA 1P59A 1WEGA 1XQOA 1XQPA 2W03A 3CW7A 3OYEA 5AN4A 3OYNA 5FRMA 2NOHA 3FHGA 2H56A 4UOBA 3OYHA 1RRSA 4PIIA 4E7JA 5DPKA 5CHZA 1XG7A 3I0XA 1N39A 4E9HA 3S3NA 1MUYA 1MUNA 2OFKA 2JG6A 2I5WA 3L2WA 3OYMA 3OY9A 3N0UA 3OS0A 2NOZA 4EW0A 4YOQA 3L2RA 1WEFA 3S6IA 4DK9A 1NKUA 3CVTA 1LMZA 1NGNA 3OYGA 3N5NX 4E7LA 4IKFA 2JHJA 2NOIA 3OYKA 2NOLA 3OYLA 4YPRA 4YPHA
chains in the Genus database with same CATH topology
1LWYA 2XHIA 4HSBA 1YQRA 1DIZA 3CWUA 4B23A 3D4VA 2ABKA 1PU7A 3F0ZA 4EVVA 1M3QA 1LWWA 4UNFA 2NOBA 2NOEA 1YQKA 1M3HA 3OH6A 1MUDA 4E9EA 4EA5A 1YQLA 4AI4A 4EW4A 3CWSA 4EJZA 1KG6A 1PU6A 3CWAA 1WEIA 1KO9A 2YG8A 4AIAA 3G0QA 4B22A 1KG7A 3KTUA 3OH9A 3I0WA 4E9FA 1N3CA 4OFEA 4OFHA 1KG3A 1FN7A 3FSPA 3CWTA 1PU8A 3FHFA 1KEAA 3IH7A 4EA4A 1KG2A 2JHNA 1RRQA 1MPGA 3KNTA 1ORPA 1ORNA 3F10A 1KQJA 1N3AA 4EJYA 3CVSA 1KG4A 1YQMA 2OFIA 1VRLA 3OGDA 5KN9A 4OFAA 1P7MA 5KN8A 1KG5A 1PVSA 1LWVA 1HU0A 4B24A 3IHOA 4B21A 1EBMA 2NOFA 2YG9A 4AI5A 1P59A 4E9GA 1WEGA 1XQOA 1XQPA 3CW7A 5AN4A 2NOHA 3FHGA 2H56A 4UOBA 1RRSA 4PIIA 5DPKA 5CHZA 1XG7A 3I0XA 1N39A 4E9HA 1MUYA 1MUNA 2OFKA 2JG6A 2I5WA 3N0UA 2NOZA 4EW0A 4YOQA 1WEFA 3S6IA 4DK9A 1NKUA 3CVTA 1LMZA 1NGNA 3N5NX 2NOIA 2JHJA 2NOLA 4YPRA 4YPHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LWY A;  2XHI A;  4HSB A;  1YQR A;  1DIZ A;  3CWU A;  4B23 A;  3D4V A;  2ABK A;  1PU7 A;  3F0Z A;  4EVV A;  1M3Q A;  1LWW A;  4UNF A;  2NOB A;  2NOE A;  1YQK A;  1M3H A;  3OH6 A;  1MUD A;  4E9E A;  4EA5 A;  1YQL A;  4AI4 A;  4EW4 A;  3CWS A;  4EJZ A;  1KG6 A;  1PU6 A;  3CWA A;  1WEI A;  1KO9 A;  2YG8 A;  4AIA A;  3G0Q A;  4B22 A;  1KG7 A;  3KTU A;  3OH9 A;  3I0W A;  4E9F A;  1N3C A;  4OFE A;  4OFH A;  1KG3 A;  1FN7 A;  3FSP A;  3CWT A;  1PU8 A;  3FHF A;  1KEA A;  3IH7 A;  4EA4 A;  1KG2 A;  2JHN A;  1RRQ A;  1MPG A;  3KNT A;  1ORP A;  1ORN A;  3F10 A;  1KQJ A;  1N3A A;  4EJY A;  3CVS A;  1KG4 A;  1YQM A;  2OFI A;  1VRL A;  3OGD A;  5KN9 A;  4OFA A;  1P7M A;  5KN8 A;  1KG5 A;  1PVS A;  1LWV A;  1HU0 A;  4B24 A;  3IHO A;  4B21 A;  1EBM A;  2NOF A;  2YG9 A;  4AI5 A;  1P59 A;  4E9G A;  1WEG A;  1XQO A;  1XQP A;  3CW7 A;  5AN4 A;  2NOH A;  3FHG A;  2H56 A;  4UOB A;  1RRS A;  4PII A;  5DPK A;  5CHZ A;  1XG7 A;  3I0X A;  1N39 A;  4E9H A;  1MUY A;  1MUN A;  2OFK A;  2JG6 A;  2I5W A;  3N0U A;  2NOZ A;  4EW0 A;  4YOQ A;  1WEF A;  3S6I A;  4DK9 A;  1NKU A;  3CVT A;  1LMZ A;  1NGN A;  3N5N X;  2NOI A;  2JHJ A;  2NOL A;  4YPR A;  4YPH A; 
#chains in the Genus database with same CATH topology
 4BE2 A;  1LWY A;  2XHI A;  4HSB A;  1YQR A;  1DIZ A;  3CWU A;  4B23 A;  4BDZ A;  5FRO A;  3D4V A;  2ABK A;  1PU7 A;  3F0Z A;  3S3M A;  4EVV A;  1M3Q A;  4BE1 A;  1LWW A;  3OYA A;  4UNF A;  2NOB A;  2NOE A;  1YQK A;  3OS2 A;  1M3H A;  3OH6 A;  4BDY A;  1MUD A;  4E9E A;  4EA5 A;  1YQL A;  4AI4 A;  4EW4 A;  3CWS A;  4EJZ A;  3LCN A;  1KG6 A;  4E7I A;  1PU6 A;  4BAC A;  3CWA A;  1WEI A;  1KO9 A;  2YG8 A;  4AIA A;  3G0Q A;  4BE0 A;  3S3O A;  4B22 A;  3NNQ A;  3R2X C;  1KG7 A;  3KTU A;  3OH9 A;  3I0W A;  3L2U A;  4E9F A;  1N3C A;  3OYF A;  4OFE A;  4OFH A;  1KG3 A;  1FN7 A;  3FSP A;  3CWT A;  1PU8 A;  3FHF A;  3VW4 A;  1KEA A;  3IH7 A;  4EA4 A;  1KG2 A;  1U84 A;  2JHN A;  2JPS A;  1RRQ A;  1MPG A;  3KNT A;  1ORP A;  1ORN A;  3OYJ A;  4NZG A;  3OYD A;  3F10 A;  3OYB A;  3L2Q A;  1KQJ A;  1N3A A;  4EJY A;  3L2V A;  3CVS A;  1KG4 A;  1YQM A;  4E7H A;  2OFI A;  1VRL A;  3OGD A;  4E7K A;  5KN9 A;  4OFA A;  1P7M A;  5KN8 A;  1KG5 A;  3OS1 A;  1PVS A;  4ZTJ A;  1HU0 A;  1LWV A;  4B24 A;  3IHO A;  3OYC A;  4B21 A;  1EBM A;  2NOF A;  2YG9 A;  4ZTF A;  5FRN A;  2V75 A;  4AI5 A;  3OYI A;  2W04 A;  4E9G A;  1P59 A;  1WEG A;  1XQO A;  1XQP A;  2W03 A;  3CW7 A;  3OYE A;  5AN4 A;  3OYN A;  5FRM A;  2NOH A;  3FHG A;  2H56 A;  4UOB A;  3OYH A;  1RRS A;  4PII A;  4E7J A;  5DPK A;  5CHZ A;  1XG7 A;  3I0X A;  1N39 A;  4E9H A;  3S3N A;  1MUY A;  1MUN A;  2OFK A;  2JG6 A;  2I5W A;  3L2W A;  3OYM A;  3OY9 A;  3N0U A;  3OS0 A;  2NOZ A;  4EW0 A;  4YOQ A;  3L2R A;  1WEF A;  3S6I A;  4DK9 A;  1NKU A;  3CVT A;  1LMZ A;  1NGN A;  3OYG A;  3N5N X;  4E7L A;  4IKF A;  2JHJ A;  2NOI A;  3OYK A;  2NOL A;  3OYL A;  4YPR A;  4YPH A; 
#chains in the Genus database with same CATH homology
 1LWY A;  2XHI A;  4HSB A;  1YQR A;  1DIZ A;  3CWU A;  4B23 A;  3D4V A;  2ABK A;  1PU7 A;  3F0Z A;  4EVV A;  1M3Q A;  1LWW A;  4UNF A;  2NOB A;  2NOE A;  1YQK A;  1M3H A;  3OH6 A;  1MUD A;  4E9E A;  4EA5 A;  1YQL A;  4AI4 A;  4EW4 A;  3CWS A;  4EJZ A;  1KG6 A;  1PU6 A;  3CWA A;  1WEI A;  1KO9 A;  2YG8 A;  4AIA A;  3G0Q A;  4B22 A;  1KG7 A;  3KTU A;  3OH9 A;  3I0W A;  4E9F A;  1N3C A;  4OFE A;  4OFH A;  1KG3 A;  1FN7 A;  3FSP A;  3CWT A;  1PU8 A;  3FHF A;  1KEA A;  3IH7 A;  4EA4 A;  1KG2 A;  2JHN A;  1RRQ A;  1MPG A;  3KNT A;  1ORP A;  1ORN A;  3F10 A;  1KQJ A;  1N3A A;  4EJY A;  3CVS A;  1KG4 A;  1YQM A;  2OFI A;  1VRL A;  3OGD A;  5KN9 A;  4OFA A;  1P7M A;  5KN8 A;  1KG5 A;  1PVS A;  1LWV A;  1HU0 A;  4B24 A;  3IHO A;  4B21 A;  1EBM A;  2NOF A;  2YG9 A;  4AI5 A;  1P59 A;  4E9G A;  1WEG A;  1XQO A;  1XQP A;  3CW7 A;  5AN4 A;  2NOH A;  3FHG A;  2H56 A;  4UOB A;  1RRS A;  4PII A;  5DPK A;  5CHZ A;  1XG7 A;  3I0X A;  1N39 A;  4E9H A;  1MUY A;  1MUN A;  2OFK A;  2JG6 A;  2I5W A;  3N0U A;  2NOZ A;  4EW0 A;  4YOQ A;  1WEF A;  3S6I A;  4DK9 A;  1NKU A;  3CVT A;  1LMZ A;  1NGN A;  3N5N X;  2NOI A;  2JHJ A;  2NOL A;  4YPR A;  4YPH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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