4E9EA

Structure of the glycosylase domain of mbd4
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
140
structure length
140
Chain Sequence
KWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Methyl-CpG-binding domain protein 4
publication title Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 45
structure length 140
sequence length 140
ec nomenclature ec 3.2.2.-:
pdb deposition date 2012-03-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 4e9eA00
1N3CA 1DIZA 4DK9A 4AI4A 4PIIA 3OGDA 2NOHA 1HU0A 1ORNA 1NGNA 1WEGA 3I0WA 3CVTA 1P7MA 1KO9A 2H56A 3IHOA 3FHFA 1YQMA 4EA4A 1MUDA 4OFHA 2NOFA 4E9GA 3CWUA 5CHZA 3KNTA 1XQPA 5DPKA 4EW0A 1WEFA 3CWSA 1KG6A 4YPRA 1RRQA 1RRSA 1MUNA 4YOQA 1PU6A 1XQOA 2JHNA 3CVSA 2NOZA 3N0UA 1XG7A 1EBMA 1YQRA 1VRLA 1LWYA 1YQLA 1KG5A 1N3AA 4YPHA 4EJYA 2JHJA 2ABKA 1LWVA 1N39A 1KG4A 3N5NX 1PU8A 2NOIA 2YG9A 1ORPA 3CW7A 4B22A 4UNFA 3G0QA 1YQKA 1PVSA 4B23A 1KG7A 1NKUA 4HSBA 4E9HA 4AI5A 1P59A 3S6IA 4OFAA 1MPGA 4EVVA 1KQJA 5AN4A 2NOEA 3D4VA 2YG8A 2NOLA 3I0XA 4B24A 1M3QA 1WEIA 4E9FA 2NOBA 3OH6A 3FSPA 4AIAA 2XHIA 4OFEA 3KTUA 1M3HA 3CWTA 1LMZA 5KN9A 1PU7A 1MUYA 2I5WA 5KN8A 4EA5A 3IH7A 3F10A 1FN7A 2OFIA 4E9EA 4EJZA 1LWWA 1KG3A 3F0ZA 3CWAA 1KG2A 2JG6A 3OH9A 4UOBA 4EW4A 1KEAA 2OFKA 3FHGA 4B21A
chains in the Genus database with same CATH superfamily
1N3CA 3LCNA 1DIZA 3S3MA 4DK9A 3OYBA 4AI4A 4PIIA 3OGDA 4E7JA 2NOHA 3L2RA 1HU0A 1ORNA 1NGNA 1WEGA 3I0WA 3CVTA 1P7MA 4BE1A 1KO9A 4E7HA 2H56A 3IHOA 3FHFA 4BDZA 3OYDA 1YQMA 4EA4A 1MUDA 4OFHA 2NOFA 4E9GA 3CWUA 5CHZA 3KNTA 5FROA 1XQPA 5DPKA 3OYFA 4EW0A 3VW4A 2W03A 4NZGA 1WEFA 4BE2A 3CWSA 1KG6A 4E7LA 4YPRA 1RRQA 1RRSA 1MUNA 3R2XC 4E7KA 4YOQA 1PU6A 1XQOA 3S3OA 5FRMA 2JHNA 3CVSA 3OYIA 2NOZA 3N0UA 1XG7A 2JPSA 3OS2A 1U84A 3L2UA 1VRLA 1YQRA 1LWYA 2W04A 1EBMA 1YQLA 1KG5A 1N3AA 4YPHA 4EJYA 2JHJA 2ABKA 4IKFA 4ZTFA 1LWVA 3OYGA 3OYEA 1N39A 1KG4A 3N5NX 1PU8A 2NOIA 3OYJA 2YG9A 1ORPA 3CW7A 3OS1A 4B22A 2V75A 4UNFA 3OYHA 3G0QA 1YQKA 1PVSA 4B23A 1KG7A 1NKUA 4HSBA 4E9HA 4AI5A 1P59A 3S6IA 4OFAA 1MPGA 4EVVA 1KQJA 5AN4A 2NOEA 5FRNA 3D4VA 2YG8A 3OYLA 3OYNA 3I0XA 2NOLA 3OYMA 3L2QA 4B24A 1M3QA 1WEIA 4E9FA 2NOBA 3OYCA 3OH6A 3FSPA 4AIAA 2XHIA 4OFEA 3KTUA 1M3HA 3CWTA 1LMZA 5KN9A 1PU7A 1MUYA 4BACA 4E7IA 2I5WA 5KN8A 3NNQA 4EA5A 3IH7A 4BDYA 4ZTJA 3F10A 1FN7A 2OFIA 4E9EA 4EJZA 1LWWA 1KG3A 3F0ZA 3OY9A 3CWAA 1KG2A 2JG6A 3L2VA 3OH9A 4UOBA 4BE0A 4EW4A 3OS0A 1KEAA 2OFKA 3FHGA 3OYAA 4B21A 3L2WA 3OYKA 3S3NA
chains in the Genus database with same CATH topology
1N3CA 1DIZA 4DK9A 4AI4A 4PIIA 3OGDA 2NOHA 1HU0A 1ORNA 1NGNA 1WEGA 3I0WA 3CVTA 1P7MA 1KO9A 2H56A 3IHOA 3FHFA 1YQMA 4EA4A 1MUDA 4OFHA 2NOFA 4E9GA 3CWUA 5CHZA 3KNTA 1XQPA 5DPKA 4EW0A 1WEFA 3CWSA 1KG6A 4YPRA 1RRQA 1RRSA 1MUNA 4YOQA 1PU6A 1XQOA 2JHNA 3CVSA 2NOZA 3N0UA 1XG7A 1EBMA 1YQRA 1VRLA 1LWYA 1YQLA 1KG5A 1N3AA 4YPHA 4EJYA 2JHJA 2ABKA 1LWVA 1N39A 1KG4A 3N5NX 1PU8A 2NOIA 2YG9A 1ORPA 3CW7A 4B22A 4UNFA 3G0QA 1YQKA 1PVSA 4B23A 1KG7A 1NKUA 4HSBA 4E9HA 4AI5A 1P59A 3S6IA 4OFAA 1MPGA 4EVVA 1KQJA 5AN4A 2NOEA 3D4VA 2YG8A 2NOLA 3I0XA 4B24A 1M3QA 1WEIA 4E9FA 2NOBA 3OH6A 3FSPA 4AIAA 2XHIA 4OFEA 3KTUA 1M3HA 3CWTA 1LMZA 5KN9A 1PU7A 1MUYA 2I5WA 5KN8A 4EA5A 3IH7A 3F10A 1FN7A 2OFIA 4E9EA 4EJZA 1LWWA 1KG3A 3F0ZA 3CWAA 1KG2A 2JG6A 3OH9A 4UOBA 4EW4A 1KEAA 2OFKA 3FHGA 4B21A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N3C A;  1DIZ A;  4DK9 A;  4AI4 A;  4PII A;  3OGD A;  2NOH A;  1HU0 A;  1ORN A;  1NGN A;  1WEG A;  3I0W A;  3CVT A;  1P7M A;  1KO9 A;  2H56 A;  3IHO A;  3FHF A;  1YQM A;  4EA4 A;  1MUD A;  4OFH A;  2NOF A;  4E9G A;  3CWU A;  5CHZ A;  3KNT A;  1XQP A;  5DPK A;  4EW0 A;  1WEF A;  3CWS A;  1KG6 A;  4YPR A;  1RRQ A;  1RRS A;  1MUN A;  4YOQ A;  1PU6 A;  1XQO A;  2JHN A;  3CVS A;  2NOZ A;  3N0U A;  1XG7 A;  1EBM A;  1YQR A;  1VRL A;  1LWY A;  1YQL A;  1KG5 A;  1N3A A;  4YPH A;  4EJY A;  2JHJ A;  2ABK A;  1LWV A;  1N39 A;  1KG4 A;  3N5N X;  1PU8 A;  2NOI A;  2YG9 A;  1ORP A;  3CW7 A;  4B22 A;  4UNF A;  3G0Q A;  1YQK A;  1PVS A;  4B23 A;  1KG7 A;  1NKU A;  4HSB A;  4E9H A;  4AI5 A;  1P59 A;  3S6I A;  4OFA A;  1MPG A;  4EVV A;  1KQJ A;  5AN4 A;  2NOE A;  3D4V A;  2YG8 A;  2NOL A;  3I0X A;  4B24 A;  1M3Q A;  1WEI A;  4E9F A;  2NOB A;  3OH6 A;  3FSP A;  4AIA A;  2XHI A;  4OFE A;  3KTU A;  1M3H A;  3CWT A;  1LMZ A;  5KN9 A;  1PU7 A;  1MUY A;  2I5W A;  5KN8 A;  4EA5 A;  3IH7 A;  3F10 A;  1FN7 A;  2OFI A;  4E9E A;  4EJZ A;  1LWW A;  1KG3 A;  3F0Z A;  3CWA A;  1KG2 A;  2JG6 A;  3OH9 A;  4UOB A;  4EW4 A;  1KEA A;  2OFK A;  3FHG A;  4B21 A; 
#chains in the Genus database with same CATH topology
 1N3C A;  3LCN A;  1DIZ A;  3S3M A;  4DK9 A;  3OYB A;  4AI4 A;  4PII A;  3OGD A;  4E7J A;  2NOH A;  3L2R A;  1HU0 A;  1ORN A;  1NGN A;  1WEG A;  3I0W A;  3CVT A;  1P7M A;  4BE1 A;  1KO9 A;  4E7H A;  2H56 A;  3IHO A;  3FHF A;  4BDZ A;  3OYD A;  1YQM A;  4EA4 A;  1MUD A;  4OFH A;  2NOF A;  4E9G A;  3CWU A;  5CHZ A;  3KNT A;  5FRO A;  1XQP A;  5DPK A;  3OYF A;  4EW0 A;  3VW4 A;  2W03 A;  4NZG A;  1WEF A;  4BE2 A;  3CWS A;  1KG6 A;  4E7L A;  4YPR A;  1RRQ A;  1RRS A;  1MUN A;  3R2X C;  4E7K A;  4YOQ A;  1PU6 A;  1XQO A;  3S3O A;  5FRM A;  2JHN A;  3CVS A;  3OYI A;  2NOZ A;  3N0U A;  1XG7 A;  2JPS A;  3OS2 A;  1U84 A;  3L2U A;  1VRL A;  1YQR A;  1LWY A;  2W04 A;  1EBM A;  1YQL A;  1KG5 A;  1N3A A;  4YPH A;  4EJY A;  2JHJ A;  2ABK A;  4IKF A;  4ZTF A;  1LWV A;  3OYG A;  3OYE A;  1N39 A;  1KG4 A;  3N5N X;  1PU8 A;  2NOI A;  3OYJ A;  2YG9 A;  1ORP A;  3CW7 A;  3OS1 A;  4B22 A;  2V75 A;  4UNF A;  3OYH A;  3G0Q A;  1YQK A;  1PVS A;  4B23 A;  1KG7 A;  1NKU A;  4HSB A;  4E9H A;  4AI5 A;  1P59 A;  3S6I A;  4OFA A;  1MPG A;  4EVV A;  1KQJ A;  5AN4 A;  2NOE A;  5FRN A;  3D4V A;  2YG8 A;  3OYL A;  3OYN A;  3I0X A;  2NOL A;  3OYM A;  3L2Q A;  4B24 A;  1M3Q A;  1WEI A;  4E9F A;  2NOB A;  3OYC A;  3OH6 A;  3FSP A;  4AIA A;  2XHI A;  4OFE A;  3KTU A;  1M3H A;  3CWT A;  1LMZ A;  5KN9 A;  1PU7 A;  1MUY A;  4BAC A;  4E7I A;  2I5W A;  5KN8 A;  3NNQ A;  4EA5 A;  3IH7 A;  4BDY A;  4ZTJ A;  3F10 A;  1FN7 A;  2OFI A;  4E9E A;  4EJZ A;  1LWW A;  1KG3 A;  3F0Z A;  3OY9 A;  3CWA A;  1KG2 A;  2JG6 A;  3L2V A;  3OH9 A;  4UOB A;  4BE0 A;  4EW4 A;  3OS0 A;  1KEA A;  2OFK A;  3FHG A;  3OYA A;  4B21 A;  3L2W A;  3OYK A;  3S3N A; 
#chains in the Genus database with same CATH homology
 1N3C A;  1DIZ A;  4DK9 A;  4AI4 A;  4PII A;  3OGD A;  2NOH A;  1HU0 A;  1ORN A;  1NGN A;  1WEG A;  3I0W A;  3CVT A;  1P7M A;  1KO9 A;  2H56 A;  3IHO A;  3FHF A;  1YQM A;  4EA4 A;  1MUD A;  4OFH A;  2NOF A;  4E9G A;  3CWU A;  5CHZ A;  3KNT A;  1XQP A;  5DPK A;  4EW0 A;  1WEF A;  3CWS A;  1KG6 A;  4YPR A;  1RRQ A;  1RRS A;  1MUN A;  4YOQ A;  1PU6 A;  1XQO A;  2JHN A;  3CVS A;  2NOZ A;  3N0U A;  1XG7 A;  1EBM A;  1YQR A;  1VRL A;  1LWY A;  1YQL A;  1KG5 A;  1N3A A;  4YPH A;  4EJY A;  2JHJ A;  2ABK A;  1LWV A;  1N39 A;  1KG4 A;  3N5N X;  1PU8 A;  2NOI A;  2YG9 A;  1ORP A;  3CW7 A;  4B22 A;  4UNF A;  3G0Q A;  1YQK A;  1PVS A;  4B23 A;  1KG7 A;  1NKU A;  4HSB A;  4E9H A;  4AI5 A;  1P59 A;  3S6I A;  4OFA A;  1MPG A;  4EVV A;  1KQJ A;  5AN4 A;  2NOE A;  3D4V A;  2YG8 A;  2NOL A;  3I0X A;  4B24 A;  1M3Q A;  1WEI A;  4E9F A;  2NOB A;  3OH6 A;  3FSP A;  4AIA A;  2XHI A;  4OFE A;  3KTU A;  1M3H A;  3CWT A;  1LMZ A;  5KN9 A;  1PU7 A;  1MUY A;  2I5W A;  5KN8 A;  4EA5 A;  3IH7 A;  3F10 A;  1FN7 A;  2OFI A;  4E9E A;  4EJZ A;  1LWW A;  1KG3 A;  3F0Z A;  3CWA A;  1KG2 A;  2JG6 A;  3OH9 A;  4UOB A;  4EW4 A;  1KEA A;  2OFK A;  3FHG A;  4B21 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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