4E9EA

Structure of the glycosylase domain of mbd4
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
140
structure length
140
Chain Sequence
KWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Methyl-CpG-binding domain protein 4
publication title Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA.
pubmed doi rcsb
source organism Homo sapiens
total genus 45
structure length 140
sequence length 140
ec nomenclature ec 3.2.2.-:
pdb deposition date 2012-03-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 4e9eA00
3N0UA 5DPKA 2JHJA 5KN8A 4AIAA 1EBMA 1YQRA 4EA4A 4HSBA 1M3QA 3OH6A 2NOIA 2XHIA 4UOBA 4EW4A 3CWTA 1M3HA 2I5WA 4YPHA 3D4VA 4EJYA 1HU0A 3CVSA 1PU8A 1LWWA 1WEFA 1KG6A 2OFIA 1WEGA 2YG9A 1MUYA 1MUNA 4AI5A 3FHGA 2NOBA 4E9GA 4UNFA 1DIZA 2H56A 2YG8A 4DK9A 1ORNA 2NOFA 3KNTA 3OGDA 1FN7A 1KO9A 3CW7A 3I0XA 1MPGA 1WEIA 1LWYA 1MUDA 3KTUA 1NKUA 3CWUA 1N3AA 2NOHA 3CVTA 4B22A 4OFEA 1YQKA 1N39A 4OFHA 3FHFA 1PU7A 4OFAA 2JHNA 1KG2A 1LWVA 3S6IA 4EVVA 3F0ZA 1XQOA 4B21A 1NGNA 1KG4A 1ORPA 4B23A 1RRQA 1P59A 2ABKA 1XQPA 1XG7A 3CWSA 4EJZA 1YQLA 4B24A 1KG3A 4EA5A 2NOZA 2JG6A 3FSPA 1VRLA 1KG5A 4E9FA 1YQMA 2NOLA 3N5NX 2NOEA 1LMZA 2OFKA 1PVSA 1KEAA 4YPRA 4PIIA 4EW0A 5CHZA 3G0QA 1RRSA 4AI4A 3CWAA 1P7MA 4E9HA 5AN4A 3OH9A 3F10A 1N3CA 4YOQA 3I0WA 1KG7A 1PU6A 1KQJA 3IH7A 4E9EA 3IHOA 5KN9A
chains in the Genus database with same CATH superfamily
3N0UA 3NNQA 5DPKA 3OYFA 1U84A 2JHJA 5KN8A 4AIAA 1EBMA 1YQRA 4EA4A 4HSBA 4NZGA 3OYIA 1M3QA 3R2XC 4E7JA 3OH6A 3VW4A 2V75A 2XHIA 4UOBA 3OS2A 3OYJA 4EW4A 3CWTA 2NOIA 1M3HA 2I5WA 4YPHA 3D4VA 4EJYA 1HU0A 3CVSA 4E7HA 1PU8A 1LWWA 1WEFA 1KG6A 2OFIA 1WEGA 2YG9A 1MUYA 1MUNA 4IKFA 4AI5A 3FHGA 2NOBA 3OYMA 4E9GA 4UNFA 1DIZA 4ZTJA 2H56A 3LCNA 2YG8A 4DK9A 1ORNA 2NOFA 3KNTA 5FRMA 3OGDA 1FN7A 3OYGA 1KO9A 3L2VA 3CW7A 3I0XA 1MPGA 1WEIA 4BE1A 4E7KA 1LWYA 1MUDA 3KTUA 1NKUA 3CWUA 3S3OA 1N3AA 2NOHA 3OYCA 3CVTA 3OYKA 4B22A 4OFEA 3S3NA 3OYBA 1YQKA 4BDZA 1N39A 4OFHA 3OYLA 3FHFA 4BE0A 4BACA 1PU7A 4OFAA 3OYNA 2JHNA 1KG2A 1LWVA 3S6IA 4EVVA 3F0ZA 3S3MA 1XQOA 3L2WA 3OYHA 4E7IA 4B21A 4BE2A 1NGNA 2W04A 1KG4A 1ORPA 3OYAA 4B23A 1RRQA 4E7LA 1P59A 3L2RA 2ABKA 1XQPA 3OS0A 5FROA 1XG7A 3CWSA 4EJZA 1YQLA 4B24A 1KG3A 4EA5A 2NOZA 2JG6A 3FSPA 1VRLA 1KG5A 4E9FA 3L2UA 1YQMA 2NOLA 3N5NX 5FRNA 3OY9A 2NOEA 1LMZA 2OFKA 1PVSA 1KEAA 4YPRA 4PIIA 4EW0A 5CHZA 4ZTFA 3G0QA 1RRSA 4AI4A 2W03A 3OYDA 3CWAA 1P7MA 4E9HA 5AN4A 3OH9A 3F10A 1N3CA 4YOQA 4BDYA 3I0WA 1KG7A 1PU6A 1KQJA 3IH7A 2JPSA 3OS1A 4E9EA 3L2QA 3IHOA 3OYEA 5KN9A
chains in the Genus database with same CATH topology
3N0UA 5DPKA 2JHJA 5KN8A 4AIAA 1EBMA 1YQRA 4EA4A 4HSBA 1M3QA 3OH6A 2NOIA 2XHIA 4UOBA 4EW4A 3CWTA 1M3HA 2I5WA 4YPHA 3D4VA 4EJYA 1HU0A 3CVSA 1PU8A 1LWWA 1WEFA 1KG6A 2OFIA 1WEGA 2YG9A 1MUYA 1MUNA 4AI5A 3FHGA 2NOBA 4E9GA 4UNFA 1DIZA 2H56A 2YG8A 4DK9A 1ORNA 2NOFA 3KNTA 3OGDA 1FN7A 1KO9A 3CW7A 3I0XA 1MPGA 1WEIA 1LWYA 1MUDA 3KTUA 1NKUA 3CWUA 1N3AA 2NOHA 3CVTA 4B22A 4OFEA 1YQKA 1N39A 4OFHA 3FHFA 1PU7A 4OFAA 2JHNA 1KG2A 1LWVA 3S6IA 4EVVA 3F0ZA 1XQOA 4B21A 1NGNA 1KG4A 1ORPA 4B23A 1RRQA 1P59A 2ABKA 1XQPA 1XG7A 3CWSA 4EJZA 1YQLA 4B24A 1KG3A 4EA5A 2NOZA 2JG6A 3FSPA 1VRLA 1KG5A 4E9FA 1YQMA 2NOLA 3N5NX 2NOEA 1LMZA 2OFKA 1PVSA 1KEAA 4YPRA 4PIIA 4EW0A 5CHZA 3G0QA 1RRSA 4AI4A 3CWAA 1P7MA 4E9HA 5AN4A 3OH9A 3F10A 1N3CA 4YOQA 3I0WA 1KG7A 1PU6A 1KQJA 3IH7A 4E9EA 3IHOA 5KN9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N0U A;  5DPK A;  2JHJ A;  5KN8 A;  4AIA A;  1EBM A;  1YQR A;  4EA4 A;  4HSB A;  1M3Q A;  3OH6 A;  2NOI A;  2XHI A;  4UOB A;  4EW4 A;  3CWT A;  1M3H A;  2I5W A;  4YPH A;  3D4V A;  4EJY A;  1HU0 A;  3CVS A;  1PU8 A;  1LWW A;  1WEF A;  1KG6 A;  2OFI A;  1WEG A;  2YG9 A;  1MUY A;  1MUN A;  4AI5 A;  3FHG A;  2NOB A;  4E9G A;  4UNF A;  1DIZ A;  2H56 A;  2YG8 A;  4DK9 A;  1ORN A;  2NOF A;  3KNT A;  3OGD A;  1FN7 A;  1KO9 A;  3CW7 A;  3I0X A;  1MPG A;  1WEI A;  1LWY A;  1MUD A;  3KTU A;  1NKU A;  3CWU A;  1N3A A;  2NOH A;  3CVT A;  4B22 A;  4OFE A;  1YQK A;  1N39 A;  4OFH A;  3FHF A;  1PU7 A;  4OFA A;  2JHN A;  1KG2 A;  1LWV A;  3S6I A;  4EVV A;  3F0Z A;  1XQO A;  4B21 A;  1NGN A;  1KG4 A;  1ORP A;  4B23 A;  1RRQ A;  1P59 A;  2ABK A;  1XQP A;  1XG7 A;  3CWS A;  4EJZ A;  1YQL A;  4B24 A;  1KG3 A;  4EA5 A;  2NOZ A;  2JG6 A;  3FSP A;  1VRL A;  1KG5 A;  4E9F A;  1YQM A;  2NOL A;  3N5N X;  2NOE A;  1LMZ A;  2OFK A;  1PVS A;  1KEA A;  4YPR A;  4PII A;  4EW0 A;  5CHZ A;  3G0Q A;  1RRS A;  4AI4 A;  3CWA A;  1P7M A;  4E9H A;  5AN4 A;  3OH9 A;  3F10 A;  1N3C A;  4YOQ A;  3I0W A;  1KG7 A;  1PU6 A;  1KQJ A;  3IH7 A;  4E9E A;  3IHO A;  5KN9 A; 
#chains in the Genus database with same CATH topology
 3N0U A;  3NNQ A;  5DPK A;  3OYF A;  1U84 A;  2JHJ A;  5KN8 A;  4AIA A;  1EBM A;  1YQR A;  4EA4 A;  4HSB A;  4NZG A;  3OYI A;  1M3Q A;  3R2X C;  4E7J A;  3OH6 A;  3VW4 A;  2V75 A;  2XHI A;  4UOB A;  3OS2 A;  3OYJ A;  4EW4 A;  3CWT A;  2NOI A;  1M3H A;  2I5W A;  4YPH A;  3D4V A;  4EJY A;  1HU0 A;  3CVS A;  4E7H A;  1PU8 A;  1LWW A;  1WEF A;  1KG6 A;  2OFI A;  1WEG A;  2YG9 A;  1MUY A;  1MUN A;  4IKF A;  4AI5 A;  3FHG A;  2NOB A;  3OYM A;  4E9G A;  4UNF A;  1DIZ A;  4ZTJ A;  2H56 A;  3LCN A;  2YG8 A;  4DK9 A;  1ORN A;  2NOF A;  3KNT A;  5FRM A;  3OGD A;  1FN7 A;  3OYG A;  1KO9 A;  3L2V A;  3CW7 A;  3I0X A;  1MPG A;  1WEI A;  4BE1 A;  4E7K A;  1LWY A;  1MUD A;  3KTU A;  1NKU A;  3CWU A;  3S3O A;  1N3A A;  2NOH A;  3OYC A;  3CVT A;  3OYK A;  4B22 A;  4OFE A;  3S3N A;  3OYB A;  1YQK A;  4BDZ A;  1N39 A;  4OFH A;  3OYL A;  3FHF A;  4BE0 A;  4BAC A;  1PU7 A;  4OFA A;  3OYN A;  2JHN A;  1KG2 A;  1LWV A;  3S6I A;  4EVV A;  3F0Z A;  3S3M A;  1XQO A;  3L2W A;  3OYH A;  4E7I A;  4B21 A;  4BE2 A;  1NGN A;  2W04 A;  1KG4 A;  1ORP A;  3OYA A;  4B23 A;  1RRQ A;  4E7L A;  1P59 A;  3L2R A;  2ABK A;  1XQP A;  3OS0 A;  5FRO A;  1XG7 A;  3CWS A;  4EJZ A;  1YQL A;  4B24 A;  1KG3 A;  4EA5 A;  2NOZ A;  2JG6 A;  3FSP A;  1VRL A;  1KG5 A;  4E9F A;  3L2U A;  1YQM A;  2NOL A;  3N5N X;  5FRN A;  3OY9 A;  2NOE A;  1LMZ A;  2OFK A;  1PVS A;  1KEA A;  4YPR A;  4PII A;  4EW0 A;  5CHZ A;  4ZTF A;  3G0Q A;  1RRS A;  4AI4 A;  2W03 A;  3OYD A;  3CWA A;  1P7M A;  4E9H A;  5AN4 A;  3OH9 A;  3F10 A;  1N3C A;  4YOQ A;  4BDY A;  3I0W A;  1KG7 A;  1PU6 A;  1KQJ A;  3IH7 A;  2JPS A;  3OS1 A;  4E9E A;  3L2Q A;  3IHO A;  3OYE A;  5KN9 A; 
#chains in the Genus database with same CATH homology
 3N0U A;  5DPK A;  2JHJ A;  5KN8 A;  4AIA A;  1EBM A;  1YQR A;  4EA4 A;  4HSB A;  1M3Q A;  3OH6 A;  2NOI A;  2XHI A;  4UOB A;  4EW4 A;  3CWT A;  1M3H A;  2I5W A;  4YPH A;  3D4V A;  4EJY A;  1HU0 A;  3CVS A;  1PU8 A;  1LWW A;  1WEF A;  1KG6 A;  2OFI A;  1WEG A;  2YG9 A;  1MUY A;  1MUN A;  4AI5 A;  3FHG A;  2NOB A;  4E9G A;  4UNF A;  1DIZ A;  2H56 A;  2YG8 A;  4DK9 A;  1ORN A;  2NOF A;  3KNT A;  3OGD A;  1FN7 A;  1KO9 A;  3CW7 A;  3I0X A;  1MPG A;  1WEI A;  1LWY A;  1MUD A;  3KTU A;  1NKU A;  3CWU A;  1N3A A;  2NOH A;  3CVT A;  4B22 A;  4OFE A;  1YQK A;  1N39 A;  4OFH A;  3FHF A;  1PU7 A;  4OFA A;  2JHN A;  1KG2 A;  1LWV A;  3S6I A;  4EVV A;  3F0Z A;  1XQO A;  4B21 A;  1NGN A;  1KG4 A;  1ORP A;  4B23 A;  1RRQ A;  1P59 A;  2ABK A;  1XQP A;  1XG7 A;  3CWS A;  4EJZ A;  1YQL A;  4B24 A;  1KG3 A;  4EA5 A;  2NOZ A;  2JG6 A;  3FSP A;  1VRL A;  1KG5 A;  4E9F A;  1YQM A;  2NOL A;  3N5N X;  2NOE A;  1LMZ A;  2OFK A;  1PVS A;  1KEA A;  4YPR A;  4PII A;  4EW0 A;  5CHZ A;  3G0Q A;  1RRS A;  4AI4 A;  3CWA A;  1P7M A;  4E9H A;  5AN4 A;  3OH9 A;  3F10 A;  1N3C A;  4YOQ A;  3I0W A;  1KG7 A;  1PU6 A;  1KQJ A;  3IH7 A;  4E9E A;  3IHO A;  5KN9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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