5CHZA

Structure of wild-type human mbd4 bound to a g:t mismatch
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
140
structure length
140
Chain Sequence
WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Methyl-CpG-binding domain protein 4
publication title Structure of wild-type human MBD4 bound to a G:T mismatch
rcsb
source organism Homo sapiens
molecule tags Hydrolase/dna
total genus 47
structure length 140
sequence length 140
ec nomenclature ec 3.2.2.-:
pdb deposition date 2015-07-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 5chzA00
3CVSA 1XG7A 1M3HA 4DK9A 3S6IA 1EBMA 1DIZA 1XQPA 1LWYA 1KG4A 1YQKA 1PU6A 3G0QA 4AI5A 2I5WA 4EA4A 1KG6A 2NOFA 1KEAA 4YOQA 4OFEA 3CWTA 1PU7A 1P7MA 1KO9A 1YQMA 2ABKA 3N5NX 1WEFA 3D4VA 1N39A 4EJYA 5CHZA 2NOZA 3IH7A 1RRQA 2NOBA 2NOLA 2JG6A 2JHNA 3F10A 1FN7A 3CVTA 2OFKA 1N3AA 4YPHA 1KQJA 1MUDA 1MPGA 5KN9A 4EW0A 5KN8A 4B24A 1MUNA 2NOEA 1ORPA 2H56A 1NKUA 3KNTA 4E9EA 3CWAA 4HSBA 3FHGA 4UNFA 4OFAA 2YG9A 4EA5A 4E9FA 1HU0A 4E9HA 4B21A 3OGDA 1LWVA 4AI4A 5AN4A 1ORNA 4E9GA 3I0WA 3CWUA 4EW4A 1PVSA 4YPRA 5DPKA 1YQLA 3CWSA 2OFIA 4AIAA 1KG7A 4EVVA 2YG8A 1KG5A 1PU8A 2JHJA 1M3QA 1YQRA 4PIIA 3N0UA 4OFHA 3I0XA 3KTUA 4EJZA 1RRSA 1NGNA 3CW7A 3OH6A 3F0ZA 2XHIA 1KG2A 1LMZA 1WEGA 1LWWA 4UOBA 1WEIA 1KG3A 2NOHA 3FSPA 2NOIA 3OH9A 1XQOA 1P59A 3IHOA 1N3CA 1VRLA 3FHFA 4B22A 1MUYA 4B23A
chains in the Genus database with same CATH superfamily
3CVSA 3OS1A 3VW4A 1XG7A 4BACA 1M3HA 4DK9A 3S6IA 3L2WA 3NNQA 3OYCA 3OY9A 1EBMA 1DIZA 3OYAA 1XQPA 1LWYA 1KG4A 1YQKA 1PU6A 3G0QA 4AI5A 2I5WA 4EA4A 1KG6A 2NOFA 1KEAA 4YOQA 4OFEA 3CWTA 4NZGA 1PU7A 1P7MA 1KO9A 1YQMA 2ABKA 3N5NX 1WEFA 3D4VA 1N39A 4EJYA 5CHZA 3S3NA 2NOZA 3IH7A 1RRQA 2NOBA 2NOLA 2JG6A 2JHNA 4E7LA 3F10A 3LCNA 1FN7A 3CVTA 2OFKA 4BDYA 1N3AA 4YPHA 3L2QA 1KQJA 1MUDA 1MPGA 3S3OA 3OYBA 5KN9A 3OYEA 4BE1A 4EW0A 3OYNA 2V75A 5KN8A 4B24A 1MUNA 2NOEA 1ORPA 2JPSA 2H56A 1NKUA 3L2UA 4BE0A 3KNTA 4E9EA 4ZTJA 3OYKA 1U84A 3CWAA 4HSBA 4E7KA 3FHGA 4UNFA 4OFAA 2YG9A 4EA5A 4E9FA 3OYGA 1HU0A 4IKFA 4E9HA 4B21A 3OGDA 1LWVA 4BE2A 4AI4A 3OYLA 5AN4A 1ORNA 4E9GA 4BDZA 3I0WA 3CWUA 5FROA 4EW4A 1PVSA 4YPRA 5DPKA 1YQLA 3CWSA 2OFIA 2W03A 4AIAA 1KG7A 4EVVA 3R2XC 2YG8A 1KG5A 4E7JA 3OS2A 1PU8A 3OYMA 2JHJA 3S3MA 1M3QA 3OYJA 4PIIA 1YQRA 3N0UA 3OYDA 4OFHA 3I0XA 3KTUA 3OS0A 1RRSA 2W04A 4EJZA 1NGNA 3CW7A 3OYHA 3L2RA 3OH6A 3L2VA 3F0ZA 2XHIA 1KG2A 1LMZA 1WEGA 3OYIA 4UOBA 1LWWA 5FRNA 1WEIA 1KG3A 4E7HA 2NOHA 5FRMA 3FSPA 3OYFA 2NOIA 3OH9A 1XQOA 1P59A 3IHOA 1N3CA 4E7IA 1VRLA 3FHFA 4ZTFA 4B22A 1MUYA 4B23A
chains in the Genus database with same CATH topology
3CVSA 1XG7A 1M3HA 4DK9A 3S6IA 1EBMA 1DIZA 1XQPA 1LWYA 1KG4A 1YQKA 1PU6A 3G0QA 4AI5A 2I5WA 4EA4A 1KG6A 2NOFA 1KEAA 4YOQA 4OFEA 3CWTA 1PU7A 1P7MA 1KO9A 1YQMA 2ABKA 3N5NX 1WEFA 3D4VA 1N39A 4EJYA 5CHZA 2NOZA 3IH7A 1RRQA 2NOBA 2NOLA 2JG6A 2JHNA 3F10A 1FN7A 3CVTA 2OFKA 1N3AA 4YPHA 1KQJA 1MUDA 1MPGA 5KN9A 4EW0A 5KN8A 4B24A 1MUNA 2NOEA 1ORPA 2H56A 1NKUA 3KNTA 4E9EA 3CWAA 4HSBA 3FHGA 4UNFA 4OFAA 2YG9A 4EA5A 4E9FA 1HU0A 4E9HA 4B21A 3OGDA 1LWVA 4AI4A 5AN4A 1ORNA 4E9GA 3I0WA 3CWUA 4EW4A 1PVSA 4YPRA 5DPKA 1YQLA 3CWSA 2OFIA 4AIAA 1KG7A 4EVVA 2YG8A 1KG5A 1PU8A 2JHJA 1M3QA 1YQRA 4PIIA 3N0UA 4OFHA 3I0XA 3KTUA 4EJZA 1RRSA 1NGNA 3CW7A 3OH6A 3F0ZA 2XHIA 1KG2A 1LMZA 1WEGA 1LWWA 4UOBA 1WEIA 1KG3A 2NOHA 3FSPA 2NOIA 3OH9A 1XQOA 1P59A 3IHOA 1N3CA 1VRLA 3FHFA 4B22A 1MUYA 4B23A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CVS A;  1XG7 A;  1M3H A;  4DK9 A;  3S6I A;  1EBM A;  1DIZ A;  1XQP A;  1LWY A;  1KG4 A;  1YQK A;  1PU6 A;  3G0Q A;  4AI5 A;  2I5W A;  4EA4 A;  1KG6 A;  2NOF A;  1KEA A;  4YOQ A;  4OFE A;  3CWT A;  1PU7 A;  1P7M A;  1KO9 A;  1YQM A;  2ABK A;  3N5N X;  1WEF A;  3D4V A;  1N39 A;  4EJY A;  5CHZ A;  2NOZ A;  3IH7 A;  1RRQ A;  2NOB A;  2NOL A;  2JG6 A;  2JHN A;  3F10 A;  1FN7 A;  3CVT A;  2OFK A;  1N3A A;  4YPH A;  1KQJ A;  1MUD A;  1MPG A;  5KN9 A;  4EW0 A;  5KN8 A;  4B24 A;  1MUN A;  2NOE A;  1ORP A;  2H56 A;  1NKU A;  3KNT A;  4E9E A;  3CWA A;  4HSB A;  3FHG A;  4UNF A;  4OFA A;  2YG9 A;  4EA5 A;  4E9F A;  1HU0 A;  4E9H A;  4B21 A;  3OGD A;  1LWV A;  4AI4 A;  5AN4 A;  1ORN A;  4E9G A;  3I0W A;  3CWU A;  4EW4 A;  1PVS A;  4YPR A;  5DPK A;  1YQL A;  3CWS A;  2OFI A;  4AIA A;  1KG7 A;  4EVV A;  2YG8 A;  1KG5 A;  1PU8 A;  2JHJ A;  1M3Q A;  1YQR A;  4PII A;  3N0U A;  4OFH A;  3I0X A;  3KTU A;  4EJZ A;  1RRS A;  1NGN A;  3CW7 A;  3OH6 A;  3F0Z A;  2XHI A;  1KG2 A;  1LMZ A;  1WEG A;  1LWW A;  4UOB A;  1WEI A;  1KG3 A;  2NOH A;  3FSP A;  2NOI A;  3OH9 A;  1XQO A;  1P59 A;  3IHO A;  1N3C A;  1VRL A;  3FHF A;  4B22 A;  1MUY A;  4B23 A; 
#chains in the Genus database with same CATH topology
 3CVS A;  3OS1 A;  3VW4 A;  1XG7 A;  4BAC A;  1M3H A;  4DK9 A;  3S6I A;  3L2W A;  3NNQ A;  3OYC A;  3OY9 A;  1EBM A;  1DIZ A;  3OYA A;  1XQP A;  1LWY A;  1KG4 A;  1YQK A;  1PU6 A;  3G0Q A;  4AI5 A;  2I5W A;  4EA4 A;  1KG6 A;  2NOF A;  1KEA A;  4YOQ A;  4OFE A;  3CWT A;  4NZG A;  1PU7 A;  1P7M A;  1KO9 A;  1YQM A;  2ABK A;  3N5N X;  1WEF A;  3D4V A;  1N39 A;  4EJY A;  5CHZ A;  3S3N A;  2NOZ A;  3IH7 A;  1RRQ A;  2NOB A;  2NOL A;  2JG6 A;  2JHN A;  4E7L A;  3F10 A;  3LCN A;  1FN7 A;  3CVT A;  2OFK A;  4BDY A;  1N3A A;  4YPH A;  3L2Q A;  1KQJ A;  1MUD A;  1MPG A;  3S3O A;  3OYB A;  5KN9 A;  3OYE A;  4BE1 A;  4EW0 A;  3OYN A;  2V75 A;  5KN8 A;  4B24 A;  1MUN A;  2NOE A;  1ORP A;  2JPS A;  2H56 A;  1NKU A;  3L2U A;  4BE0 A;  3KNT A;  4E9E A;  4ZTJ A;  3OYK A;  1U84 A;  3CWA A;  4HSB A;  4E7K A;  3FHG A;  4UNF A;  4OFA A;  2YG9 A;  4EA5 A;  4E9F A;  3OYG A;  1HU0 A;  4IKF A;  4E9H A;  4B21 A;  3OGD A;  1LWV A;  4BE2 A;  4AI4 A;  3OYL A;  5AN4 A;  1ORN A;  4E9G A;  4BDZ A;  3I0W A;  3CWU A;  5FRO A;  4EW4 A;  1PVS A;  4YPR A;  5DPK A;  1YQL A;  3CWS A;  2OFI A;  2W03 A;  4AIA A;  1KG7 A;  4EVV A;  3R2X C;  2YG8 A;  1KG5 A;  4E7J A;  3OS2 A;  1PU8 A;  3OYM A;  2JHJ A;  3S3M A;  1M3Q A;  3OYJ A;  4PII A;  1YQR A;  3N0U A;  3OYD A;  4OFH A;  3I0X A;  3KTU A;  3OS0 A;  1RRS A;  2W04 A;  4EJZ A;  1NGN A;  3CW7 A;  3OYH A;  3L2R A;  3OH6 A;  3L2V A;  3F0Z A;  2XHI A;  1KG2 A;  1LMZ A;  1WEG A;  3OYI A;  4UOB A;  1LWW A;  5FRN A;  1WEI A;  1KG3 A;  4E7H A;  2NOH A;  5FRM A;  3FSP A;  3OYF A;  2NOI A;  3OH9 A;  1XQO A;  1P59 A;  3IHO A;  1N3C A;  4E7I A;  1VRL A;  3FHF A;  4ZTF A;  4B22 A;  1MUY A;  4B23 A; 
#chains in the Genus database with same CATH homology
 3CVS A;  1XG7 A;  1M3H A;  4DK9 A;  3S6I A;  1EBM A;  1DIZ A;  1XQP A;  1LWY A;  1KG4 A;  1YQK A;  1PU6 A;  3G0Q A;  4AI5 A;  2I5W A;  4EA4 A;  1KG6 A;  2NOF A;  1KEA A;  4YOQ A;  4OFE A;  3CWT A;  1PU7 A;  1P7M A;  1KO9 A;  1YQM A;  2ABK A;  3N5N X;  1WEF A;  3D4V A;  1N39 A;  4EJY A;  5CHZ A;  2NOZ A;  3IH7 A;  1RRQ A;  2NOB A;  2NOL A;  2JG6 A;  2JHN A;  3F10 A;  1FN7 A;  3CVT A;  2OFK A;  1N3A A;  4YPH A;  1KQJ A;  1MUD A;  1MPG A;  5KN9 A;  4EW0 A;  5KN8 A;  4B24 A;  1MUN A;  2NOE A;  1ORP A;  2H56 A;  1NKU A;  3KNT A;  4E9E A;  3CWA A;  4HSB A;  3FHG A;  4UNF A;  4OFA A;  2YG9 A;  4EA5 A;  4E9F A;  1HU0 A;  4E9H A;  4B21 A;  3OGD A;  1LWV A;  4AI4 A;  5AN4 A;  1ORN A;  4E9G A;  3I0W A;  3CWU A;  4EW4 A;  1PVS A;  4YPR A;  5DPK A;  1YQL A;  3CWS A;  2OFI A;  4AIA A;  1KG7 A;  4EVV A;  2YG8 A;  1KG5 A;  1PU8 A;  2JHJ A;  1M3Q A;  1YQR A;  4PII A;  3N0U A;  4OFH A;  3I0X A;  3KTU A;  4EJZ A;  1RRS A;  1NGN A;  3CW7 A;  3OH6 A;  3F0Z A;  2XHI A;  1KG2 A;  1LMZ A;  1WEG A;  1LWW A;  4UOB A;  1WEI A;  1KG3 A;  2NOH A;  3FSP A;  2NOI A;  3OH9 A;  1XQO A;  1P59 A;  3IHO A;  1N3C A;  1VRL A;  3FHF A;  4B22 A;  1MUY A;  4B23 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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