5CHZA

Structure of wild-type human mbd4 bound to a g:t mismatch
Total Genus 47
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
140
structure length
140
Chain Sequence
WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Methyl-CpG-binding domain protein 4
publication title Structure of wild-type human MBD4 bound to a G:T mismatch
rcsb
source organism Homo sapiens
molecule tags Hydrolase/dna
total genus 47
structure length 140
sequence length 140
ec nomenclature ec 3.2.2.-:
pdb deposition date 2015-07-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 5chzA00
1YQKA 4B22A 1XQOA 4B23A 3CWAA 4PIIA 4EW0A 1RRQA 4EJZA 3N0UA 2H56A 1WEIA 3CWUA 1NGNA 1ORNA 4AI5A 1PU8A 1KG7A 1KO9A 4EA5A 1PU7A 4E9HA 3IH7A 1KG6A 2NOLA 1P7MA 1WEFA 4EW4A 2NOIA 3CVSA 4B24A 1N39A 1PVSA 5AN4A 5KN9A 2JHJA 4E9FA 2NOHA 4OFHA 4EVVA 1YQMA 3I0WA 4E9EA 2JHNA 4DK9A 1MPGA 1LWYA 4YPHA 1XG7A 4HSBA 1ORPA 1KG2A 3D4VA 2OFIA 4OFEA 3OGDA 1KEAA 1YQRA 2ABKA 5DPKA 1MUYA 5KN8A 2YG9A 2YG8A 4E9GA 1N3CA 1RRSA 4UOBA 3I0XA 1WEGA 4AI4A 4YOQA 4UNFA 2I5WA 3S6IA 1DIZA 4OFAA 2NOBA 3IHOA 1KQJA 3CWTA 2JG6A 1LMZA 5CHZA 1LWWA 2NOZA 1NKUA 3OH6A 1LWVA 2NOEA 1KG3A 1MUNA 4EJYA 2OFKA 1KG4A 1VRLA 1MUDA 3FHGA 2NOFA 3FSPA 3CVTA 1PU6A 3FHFA 1HU0A 3KTUA 3N5NX 4EA4A 1N3AA 1EBMA 3CW7A 1KG5A 1YQLA 3F0ZA 1M3HA 1P59A 4YPRA 4AIAA 3KNTA 4B21A 3F10A 2XHIA 1FN7A 1M3QA 3CWSA 3OH9A 3G0QA 1XQPA
chains in the Genus database with same CATH superfamily
3L2UA 1YQKA 4B22A 1XQOA 4B23A 3NNQA 3CWAA 4PIIA 4EW0A 3VW4A 1RRQA 4EJZA 3N0UA 2H56A 4NZGA 1WEIA 3CWUA 1NGNA 1ORNA 4AI5A 1PU8A 1KG7A 3S3NA 3OYIA 3L2QA 2V75A 3L2WA 1KO9A 4BE2A 4E7HA 4EA5A 1PU7A 4ZTJA 4E9HA 3IH7A 1KG6A 2NOLA 1P7MA 1WEFA 4EW4A 2NOIA 4E7JA 3CVSA 3OYDA 4B24A 3OYKA 1PVSA 3S3OA 5AN4A 5KN9A 3OS0A 4BE0A 1N39A 2JHJA 4E9FA 2NOHA 5FRNA 4OFHA 4BE1A 4EVVA 1YQMA 3I0WA 4E9EA 2JHNA 4DK9A 1MPGA 1LWYA 4YPHA 1XG7A 4HSBA 1ORPA 1KG2A 3OY9A 3D4VA 4E7IA 4BDYA 2OFIA 4OFEA 3OGDA 1KEAA 1YQRA 2ABKA 5DPKA 1MUYA 5KN8A 2YG9A 3OYBA 2YG8A 4E9GA 4BDZA 1N3CA 1RRSA 4E7LA 4UOBA 3I0XA 1WEGA 4AI4A 4YOQA 4UNFA 2I5WA 3S6IA 3OS2A 1DIZA 4OFAA 2NOBA 3IHOA 1KQJA 3LCNA 3CWTA 2JG6A 1LMZA 5CHZA 3OYMA 3OS1A 1LWWA 2NOZA 1NKUA 3OH6A 1LWVA 3OYAA 2NOEA 1KG3A 5FRMA 1MUNA 4EJYA 2OFKA 1KG4A 1VRLA 1MUDA 3FHGA 2NOFA 3FSPA 3CVTA 1PU6A 3FHFA 2JPSA 3KTUA 1HU0A 3N5NX 3R2XC 4BACA 2W04A 4EA4A 1N3AA 1EBMA 3CW7A 1KG5A 3L2RA 1YQLA 3F0ZA 3OYJA 1M3HA 3OYEA 1P59A 4IKFA 4YPRA 3OYNA 4AIAA 3OYGA 1U84A 3KNTA 3S3MA 4B21A 3OYLA 3F10A 2XHIA 3OYFA 1FN7A 1M3QA 2W03A 3OYHA 3CWSA 3OH9A 3G0QA 4ZTFA 3L2VA 4E7KA 5FROA 3OYCA 1XQPA
chains in the Genus database with same CATH topology
1YQKA 4B22A 1XQOA 4B23A 3CWAA 4PIIA 4EW0A 1RRQA 4EJZA 3N0UA 2H56A 1WEIA 3CWUA 1NGNA 1ORNA 4AI5A 1PU8A 1KG7A 1KO9A 4EA5A 1PU7A 4E9HA 3IH7A 1KG6A 2NOLA 1P7MA 1WEFA 4EW4A 2NOIA 3CVSA 4B24A 1N39A 1PVSA 5AN4A 5KN9A 2JHJA 4E9FA 2NOHA 4OFHA 4EVVA 1YQMA 3I0WA 4E9EA 2JHNA 4DK9A 1MPGA 1LWYA 4YPHA 1XG7A 4HSBA 1ORPA 1KG2A 3D4VA 2OFIA 4OFEA 3OGDA 1KEAA 1YQRA 2ABKA 5DPKA 1MUYA 5KN8A 2YG9A 2YG8A 4E9GA 1N3CA 1RRSA 4UOBA 3I0XA 1WEGA 4AI4A 4YOQA 4UNFA 2I5WA 3S6IA 1DIZA 4OFAA 2NOBA 3IHOA 1KQJA 3CWTA 2JG6A 1LMZA 5CHZA 1LWWA 2NOZA 1NKUA 3OH6A 1LWVA 2NOEA 1KG3A 1MUNA 4EJYA 2OFKA 1KG4A 1VRLA 1MUDA 3FHGA 2NOFA 3FSPA 3CVTA 1PU6A 3FHFA 1HU0A 3KTUA 3N5NX 4EA4A 1N3AA 1EBMA 3CW7A 1KG5A 1YQLA 3F0ZA 1M3HA 1P59A 4YPRA 4AIAA 3KNTA 4B21A 3F10A 2XHIA 1FN7A 1M3QA 3CWSA 3OH9A 3G0QA 1XQPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YQK A;  4B22 A;  1XQO A;  4B23 A;  3CWA A;  4PII A;  4EW0 A;  1RRQ A;  4EJZ A;  3N0U A;  2H56 A;  1WEI A;  3CWU A;  1NGN A;  1ORN A;  4AI5 A;  1PU8 A;  1KG7 A;  1KO9 A;  4EA5 A;  1PU7 A;  4E9H A;  3IH7 A;  1KG6 A;  2NOL A;  1P7M A;  1WEF A;  4EW4 A;  2NOI A;  3CVS A;  4B24 A;  1N39 A;  1PVS A;  5AN4 A;  5KN9 A;  2JHJ A;  4E9F A;  2NOH A;  4OFH A;  4EVV A;  1YQM A;  3I0W A;  4E9E A;  2JHN A;  4DK9 A;  1MPG A;  1LWY A;  4YPH A;  1XG7 A;  4HSB A;  1ORP A;  1KG2 A;  3D4V A;  2OFI A;  4OFE A;  3OGD A;  1KEA A;  1YQR A;  2ABK A;  5DPK A;  1MUY A;  5KN8 A;  2YG9 A;  2YG8 A;  4E9G A;  1N3C A;  1RRS A;  4UOB A;  3I0X A;  1WEG A;  4AI4 A;  4YOQ A;  4UNF A;  2I5W A;  3S6I A;  1DIZ A;  4OFA A;  2NOB A;  3IHO A;  1KQJ A;  3CWT A;  2JG6 A;  1LMZ A;  5CHZ A;  1LWW A;  2NOZ A;  1NKU A;  3OH6 A;  1LWV A;  2NOE A;  1KG3 A;  1MUN A;  4EJY A;  2OFK A;  1KG4 A;  1VRL A;  1MUD A;  3FHG A;  2NOF A;  3FSP A;  3CVT A;  1PU6 A;  3FHF A;  1HU0 A;  3KTU A;  3N5N X;  4EA4 A;  1N3A A;  1EBM A;  3CW7 A;  1KG5 A;  1YQL A;  3F0Z A;  1M3H A;  1P59 A;  4YPR A;  4AIA A;  3KNT A;  4B21 A;  3F10 A;  2XHI A;  1FN7 A;  1M3Q A;  3CWS A;  3OH9 A;  3G0Q A;  1XQP A; 
#chains in the Genus database with same CATH topology
 3L2U A;  1YQK A;  4B22 A;  1XQO A;  4B23 A;  3NNQ A;  3CWA A;  4PII A;  4EW0 A;  3VW4 A;  1RRQ A;  4EJZ A;  3N0U A;  2H56 A;  4NZG A;  1WEI A;  3CWU A;  1NGN A;  1ORN A;  4AI5 A;  1PU8 A;  1KG7 A;  3S3N A;  3OYI A;  3L2Q A;  2V75 A;  3L2W A;  1KO9 A;  4BE2 A;  4E7H A;  4EA5 A;  1PU7 A;  4ZTJ A;  4E9H A;  3IH7 A;  1KG6 A;  2NOL A;  1P7M A;  1WEF A;  4EW4 A;  2NOI A;  4E7J A;  3CVS A;  3OYD A;  4B24 A;  3OYK A;  1PVS A;  3S3O A;  5AN4 A;  5KN9 A;  3OS0 A;  4BE0 A;  1N39 A;  2JHJ A;  4E9F A;  2NOH A;  5FRN A;  4OFH A;  4BE1 A;  4EVV A;  1YQM A;  3I0W A;  4E9E A;  2JHN A;  4DK9 A;  1MPG A;  1LWY A;  4YPH A;  1XG7 A;  4HSB A;  1ORP A;  1KG2 A;  3OY9 A;  3D4V A;  4E7I A;  4BDY A;  2OFI A;  4OFE A;  3OGD A;  1KEA A;  1YQR A;  2ABK A;  5DPK A;  1MUY A;  5KN8 A;  2YG9 A;  3OYB A;  2YG8 A;  4E9G A;  4BDZ A;  1N3C A;  1RRS A;  4E7L A;  4UOB A;  3I0X A;  1WEG A;  4AI4 A;  4YOQ A;  4UNF A;  2I5W A;  3S6I A;  3OS2 A;  1DIZ A;  4OFA A;  2NOB A;  3IHO A;  1KQJ A;  3LCN A;  3CWT A;  2JG6 A;  1LMZ A;  5CHZ A;  3OYM A;  3OS1 A;  1LWW A;  2NOZ A;  1NKU A;  3OH6 A;  1LWV A;  3OYA A;  2NOE A;  1KG3 A;  5FRM A;  1MUN A;  4EJY A;  2OFK A;  1KG4 A;  1VRL A;  1MUD A;  3FHG A;  2NOF A;  3FSP A;  3CVT A;  1PU6 A;  3FHF A;  2JPS A;  3KTU A;  1HU0 A;  3N5N X;  3R2X C;  4BAC A;  2W04 A;  4EA4 A;  1N3A A;  1EBM A;  3CW7 A;  1KG5 A;  3L2R A;  1YQL A;  3F0Z A;  3OYJ A;  1M3H A;  3OYE A;  1P59 A;  4IKF A;  4YPR A;  3OYN A;  4AIA A;  3OYG A;  1U84 A;  3KNT A;  3S3M A;  4B21 A;  3OYL A;  3F10 A;  2XHI A;  3OYF A;  1FN7 A;  1M3Q A;  2W03 A;  3OYH A;  3CWS A;  3OH9 A;  3G0Q A;  4ZTF A;  3L2V A;  4E7K A;  5FRO A;  3OYC A;  1XQP A; 
#chains in the Genus database with same CATH homology
 1YQK A;  4B22 A;  1XQO A;  4B23 A;  3CWA A;  4PII A;  4EW0 A;  1RRQ A;  4EJZ A;  3N0U A;  2H56 A;  1WEI A;  3CWU A;  1NGN A;  1ORN A;  4AI5 A;  1PU8 A;  1KG7 A;  1KO9 A;  4EA5 A;  1PU7 A;  4E9H A;  3IH7 A;  1KG6 A;  2NOL A;  1P7M A;  1WEF A;  4EW4 A;  2NOI A;  3CVS A;  4B24 A;  1N39 A;  1PVS A;  5AN4 A;  5KN9 A;  2JHJ A;  4E9F A;  2NOH A;  4OFH A;  4EVV A;  1YQM A;  3I0W A;  4E9E A;  2JHN A;  4DK9 A;  1MPG A;  1LWY A;  4YPH A;  1XG7 A;  4HSB A;  1ORP A;  1KG2 A;  3D4V A;  2OFI A;  4OFE A;  3OGD A;  1KEA A;  1YQR A;  2ABK A;  5DPK A;  1MUY A;  5KN8 A;  2YG9 A;  2YG8 A;  4E9G A;  1N3C A;  1RRS A;  4UOB A;  3I0X A;  1WEG A;  4AI4 A;  4YOQ A;  4UNF A;  2I5W A;  3S6I A;  1DIZ A;  4OFA A;  2NOB A;  3IHO A;  1KQJ A;  3CWT A;  2JG6 A;  1LMZ A;  5CHZ A;  1LWW A;  2NOZ A;  1NKU A;  3OH6 A;  1LWV A;  2NOE A;  1KG3 A;  1MUN A;  4EJY A;  2OFK A;  1KG4 A;  1VRL A;  1MUD A;  3FHG A;  2NOF A;  3FSP A;  3CVT A;  1PU6 A;  3FHF A;  1HU0 A;  3KTU A;  3N5N X;  4EA4 A;  1N3A A;  1EBM A;  3CW7 A;  1KG5 A;  1YQL A;  3F0Z A;  1M3H A;  1P59 A;  4YPR A;  4AIA A;  3KNT A;  4B21 A;  3F10 A;  2XHI A;  1FN7 A;  1M3Q A;  3CWS A;  3OH9 A;  3G0Q A;  1XQP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...