1WEGA

Catalytic domain of muty from escherichia coli k142a mutant
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVARVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords A/G-specific adenine glycosylase
publication title Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb
source organism Escherichia coli
total genus 77
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2004-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1wegA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1wegA01
3N0UA 1P7MA 3CVTA 5KN9A 2H56A 1YQKA 1EBMA 3FHGA 3CWSA 4AI4A 1LWVA 4EW0A 4YOQA 2NOBA 2YG9A 4AI5A 3KNTA 2ABKA 2NOEA 1LWYA 1HU0A 2JHNA 3F10A 4OFHA 3CWAA 5AN4A 1MUYA 3OH6A 4UOBA 1P59A 2JHJA 2NOIA 1NGNA 3IHOA 4YPHA 4B22A 1KQJA 3D4VA 2YG8A 1XG7A 3CW7A 1KG3A 1M3QA 4UNFA 1PVSA 1YQMA 1MUDA 1N3CA 1KEAA 2NOFA 2I5WA 4E9FA 4OFAA 2JG6A 3IH7A 1KG6A 1KO9A 3I0WA 3OGDA 4YPRA 4EW4A 1N39A 1XQPA 3CVSA 4E9EA 1MUNA 1XQOA 1YQLA 3KTUA 1FN7A 4E9GA 3I0XA 5DPKA 1KG5A 4HSBA 1PU6A 4EA5A 4AIAA 1KG4A 1PU7A 1MPGA 5CHZA 4EJZA 1KG2A 3G0QA 3OH9A 4B21A 1NKUA 4EJYA 1RRSA 4EA4A 2NOHA 1KG7A 1WEIA 4PIIA 1WEFA 1N3AA 1PU8A 4OFEA 3F0ZA 1ORPA 1LWWA 4B24A 1RRQA 2OFKA 1YQRA 3CWTA 1DIZA 3CWUA 3FSPA 1WEGA 2OFIA 4EVVA 4DK9A 4B23A 1ORNA 2NOLA 5KN8A 1LMZA 4E9HA 3FHFA 1M3HA 2XHIA 2NOZA 1VRLA 3S6IA 3N5NX
chains in the Genus database with same CATH superfamily
3OS2A 3N0UA 4E7KA 1P7MA 3CVTA 3L2VA 5KN9A 2H56A 1YQKA 1EBMA 3FHGA 3CWSA 4AI4A 3S3MA 1LWVA 3OYFA 4YOQA 4EW0A 2NOBA 2YG9A 3OS0A 4AI5A 3KNTA 2ABKA 2NOEA 1LWYA 1HU0A 2JHNA 3F10A 4OFHA 3CWAA 5AN4A 1MUYA 3OH6A 4UOBA 3S3NA 1P59A 2JHJA 4IKFA 2NOIA 4E7HA 1NGNA 3IHOA 3L2RA 3OYJA 4YPHA 3OYNA 4B22A 5FRMA 3OYGA 1KQJA 3D4VA 2YG8A 1XG7A 3CW7A 1KG3A 2W03A 4ZTJA 1M3QA 4UNFA 1PVSA 3OYAA 3OYKA 4BE2A 3OYMA 1YQMA 3L2QA 1MUDA 3OYCA 1N3CA 1KEAA 2NOFA 2I5WA 4E9FA 4OFAA 2JG6A 3LCNA 3IH7A 1KG6A 1KO9A 3I0WA 3OGDA 4E7IA 4YPRA 4EW4A 1N39A 1XQPA 3CVSA 4E7JA 4BDZA 4E9EA 1MUNA 1XQOA 1YQLA 3KTUA 1FN7A 4E9GA 3I0XA 4ZTFA 4BE1A 1U84A 5DPKA 1KG5A 4HSBA 4BDYA 3L2WA 4BE0A 1PU6A 4EA5A 4AIAA 1KG4A 1PU7A 1MPGA 3VW4A 5FRNA 3OYHA 5CHZA 4EJZA 1KG2A 2V75A 3G0QA 3OH9A 3OY9A 1NKUA 4B21A 1RRSA 4EJYA 4EA4A 2NOHA 4NZGA 1KG7A 1WEIA 2JPSA 4PIIA 1WEFA 1N3AA 1PU8A 4OFEA 3F0ZA 1ORPA 1LWWA 4B24A 3L2UA 2OFKA 1RRQA 1YQRA 3CWTA 3NNQA 1DIZA 3OYBA 3CWUA 3FSPA 1WEGA 2OFIA 4EVVA 4DK9A 4B23A 1ORNA 3OYIA 2NOLA 5KN8A 3OYDA 1LMZA 3OS1A 4E9HA 3FHFA 5FROA 1M3HA 3OYLA 2XHIA 3OYEA 2NOZA 1VRLA 2W04A 4E7LA 3S6IA 4BACA 3N5NX 3S3OA 3R2XC
chains in the Genus database with same CATH topology
3N0UA 1P7MA 3CVTA 5KN9A 2H56A 1YQKA 1EBMA 3FHGA 3CWSA 4AI4A 1LWVA 4EW0A 4YOQA 2NOBA 2YG9A 4AI5A 3KNTA 2ABKA 2NOEA 1LWYA 1HU0A 2JHNA 3F10A 4OFHA 3CWAA 5AN4A 1MUYA 3OH6A 4UOBA 1P59A 2JHJA 2NOIA 1NGNA 3IHOA 4YPHA 4B22A 1KQJA 3D4VA 2YG8A 1XG7A 3CW7A 1KG3A 1M3QA 4UNFA 1PVSA 1YQMA 1MUDA 1N3CA 1KEAA 2NOFA 2I5WA 4E9FA 4OFAA 2JG6A 3IH7A 1KG6A 1KO9A 3I0WA 3OGDA 4YPRA 4EW4A 1N39A 1XQPA 3CVSA 4E9EA 1MUNA 1XQOA 1YQLA 3KTUA 1FN7A 4E9GA 3I0XA 5DPKA 1KG5A 4HSBA 1PU6A 4EA5A 4AIAA 1KG4A 1PU7A 1MPGA 5CHZA 4EJZA 1KG2A 3G0QA 3OH9A 4B21A 1NKUA 4EJYA 1RRSA 4EA4A 2NOHA 1KG7A 1WEIA 4PIIA 1WEFA 1N3AA 1PU8A 4OFEA 3F0ZA 1ORPA 1LWWA 4B24A 1RRQA 2OFKA 1YQRA 3CWTA 1DIZA 3CWUA 3FSPA 1WEGA 2OFIA 4EVVA 4DK9A 4B23A 1ORNA 2NOLA 5KN8A 1LMZA 4E9HA 3FHFA 1M3HA 2XHIA 2NOZA 1VRLA 3S6IA 3N5NX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N0U A;  1P7M A;  3CVT A;  5KN9 A;  2H56 A;  1YQK A;  1EBM A;  3FHG A;  3CWS A;  4AI4 A;  1LWV A;  4EW0 A;  4YOQ A;  2NOB A;  2YG9 A;  4AI5 A;  3KNT A;  2ABK A;  2NOE A;  1LWY A;  1HU0 A;  2JHN A;  3F10 A;  4OFH A;  3CWA A;  5AN4 A;  1MUY A;  3OH6 A;  4UOB A;  1P59 A;  2JHJ A;  2NOI A;  1NGN A;  3IHO A;  4YPH A;  4B22 A;  1KQJ A;  3D4V A;  2YG8 A;  1XG7 A;  3CW7 A;  1KG3 A;  1M3Q A;  4UNF A;  1PVS A;  1YQM A;  1MUD A;  1N3C A;  1KEA A;  2NOF A;  2I5W A;  4E9F A;  4OFA A;  2JG6 A;  3IH7 A;  1KG6 A;  1KO9 A;  3I0W A;  3OGD A;  4YPR A;  4EW4 A;  1N39 A;  1XQP A;  3CVS A;  4E9E A;  1MUN A;  1XQO A;  1YQL A;  3KTU A;  1FN7 A;  4E9G A;  3I0X A;  5DPK A;  1KG5 A;  4HSB A;  1PU6 A;  4EA5 A;  4AIA A;  1KG4 A;  1PU7 A;  1MPG A;  5CHZ A;  4EJZ A;  1KG2 A;  3G0Q A;  3OH9 A;  4B21 A;  1NKU A;  4EJY A;  1RRS A;  4EA4 A;  2NOH A;  1KG7 A;  1WEI A;  4PII A;  1WEF A;  1N3A A;  1PU8 A;  4OFE A;  3F0Z A;  1ORP A;  1LWW A;  4B24 A;  1RRQ A;  2OFK A;  1YQR A;  3CWT A;  1DIZ A;  3CWU A;  3FSP A;  1WEG A;  2OFI A;  4EVV A;  4DK9 A;  4B23 A;  1ORN A;  2NOL A;  5KN8 A;  1LMZ A;  4E9H A;  3FHF A;  1M3H A;  2XHI A;  2NOZ A;  1VRL A;  3S6I A;  3N5N X; 
#chains in the Genus database with same CATH topology
 3OS2 A;  3N0U A;  4E7K A;  1P7M A;  3CVT A;  3L2V A;  5KN9 A;  2H56 A;  1YQK A;  1EBM A;  3FHG A;  3CWS A;  4AI4 A;  3S3M A;  1LWV A;  3OYF A;  4YOQ A;  4EW0 A;  2NOB A;  2YG9 A;  3OS0 A;  4AI5 A;  3KNT A;  2ABK A;  2NOE A;  1LWY A;  1HU0 A;  2JHN A;  3F10 A;  4OFH A;  3CWA A;  5AN4 A;  1MUY A;  3OH6 A;  4UOB A;  3S3N A;  1P59 A;  2JHJ A;  4IKF A;  2NOI A;  4E7H A;  1NGN A;  3IHO A;  3L2R A;  3OYJ A;  4YPH A;  3OYN A;  4B22 A;  5FRM A;  3OYG A;  1KQJ A;  3D4V A;  2YG8 A;  1XG7 A;  3CW7 A;  1KG3 A;  2W03 A;  4ZTJ A;  1M3Q A;  4UNF A;  1PVS A;  3OYA A;  3OYK A;  4BE2 A;  3OYM A;  1YQM A;  3L2Q A;  1MUD A;  3OYC A;  1N3C A;  1KEA A;  2NOF A;  2I5W A;  4E9F A;  4OFA A;  2JG6 A;  3LCN A;  3IH7 A;  1KG6 A;  1KO9 A;  3I0W A;  3OGD A;  4E7I A;  4YPR A;  4EW4 A;  1N39 A;  1XQP A;  3CVS A;  4E7J A;  4BDZ A;  4E9E A;  1MUN A;  1XQO A;  1YQL A;  3KTU A;  1FN7 A;  4E9G A;  3I0X A;  4ZTF A;  4BE1 A;  1U84 A;  5DPK A;  1KG5 A;  4HSB A;  4BDY A;  3L2W A;  4BE0 A;  1PU6 A;  4EA5 A;  4AIA A;  1KG4 A;  1PU7 A;  1MPG A;  3VW4 A;  5FRN A;  3OYH A;  5CHZ A;  4EJZ A;  1KG2 A;  2V75 A;  3G0Q A;  3OH9 A;  3OY9 A;  1NKU A;  4B21 A;  1RRS A;  4EJY A;  4EA4 A;  2NOH A;  4NZG A;  1KG7 A;  1WEI A;  2JPS A;  4PII A;  1WEF A;  1N3A A;  1PU8 A;  4OFE A;  3F0Z A;  1ORP A;  1LWW A;  4B24 A;  3L2U A;  2OFK A;  1RRQ A;  1YQR A;  3CWT A;  3NNQ A;  1DIZ A;  3OYB A;  3CWU A;  3FSP A;  1WEG A;  2OFI A;  4EVV A;  4DK9 A;  4B23 A;  1ORN A;  3OYI A;  2NOL A;  5KN8 A;  3OYD A;  1LMZ A;  3OS1 A;  4E9H A;  3FHF A;  5FRO A;  1M3H A;  3OYL A;  2XHI A;  3OYE A;  2NOZ A;  1VRL A;  2W04 A;  4E7L A;  3S6I A;  4BAC A;  3N5N X;  3S3O A;  3R2X C; 
#chains in the Genus database with same CATH homology
 3N0U A;  1P7M A;  3CVT A;  5KN9 A;  2H56 A;  1YQK A;  1EBM A;  3FHG A;  3CWS A;  4AI4 A;  1LWV A;  4EW0 A;  4YOQ A;  2NOB A;  2YG9 A;  4AI5 A;  3KNT A;  2ABK A;  2NOE A;  1LWY A;  1HU0 A;  2JHN A;  3F10 A;  4OFH A;  3CWA A;  5AN4 A;  1MUY A;  3OH6 A;  4UOB A;  1P59 A;  2JHJ A;  2NOI A;  1NGN A;  3IHO A;  4YPH A;  4B22 A;  1KQJ A;  3D4V A;  2YG8 A;  1XG7 A;  3CW7 A;  1KG3 A;  1M3Q A;  4UNF A;  1PVS A;  1YQM A;  1MUD A;  1N3C A;  1KEA A;  2NOF A;  2I5W A;  4E9F A;  4OFA A;  2JG6 A;  3IH7 A;  1KG6 A;  1KO9 A;  3I0W A;  3OGD A;  4YPR A;  4EW4 A;  1N39 A;  1XQP A;  3CVS A;  4E9E A;  1MUN A;  1XQO A;  1YQL A;  3KTU A;  1FN7 A;  4E9G A;  3I0X A;  5DPK A;  1KG5 A;  4HSB A;  1PU6 A;  4EA5 A;  4AIA A;  1KG4 A;  1PU7 A;  1MPG A;  5CHZ A;  4EJZ A;  1KG2 A;  3G0Q A;  3OH9 A;  4B21 A;  1NKU A;  4EJY A;  1RRS A;  4EA4 A;  2NOH A;  1KG7 A;  1WEI A;  4PII A;  1WEF A;  1N3A A;  1PU8 A;  4OFE A;  3F0Z A;  1ORP A;  1LWW A;  4B24 A;  1RRQ A;  2OFK A;  1YQR A;  3CWT A;  1DIZ A;  3CWU A;  3FSP A;  1WEG A;  2OFI A;  4EVV A;  4DK9 A;  4B23 A;  1ORN A;  2NOL A;  5KN8 A;  1LMZ A;  4E9H A;  3FHF A;  1M3H A;  2XHI A;  2NOZ A;  1VRL A;  3S6I A;  3N5N X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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