1WEGA

Catalytic domain of muty from escherichia coli k142a mutant
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVARVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 77
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2004-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1wegA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1wegA01
2H56A 3F0ZA 4B21A 3CW7A 1PU7A 1PVSA 3N5NX 4YOQA 1MUNA 4EJZA 4UOBA 1N39A 4UNFA 4EJYA 2I5WA 1WEGA 3CVTA 4HSBA 3FHGA 1KG3A 3IH7A 1MPGA 4YPRA 1NGNA 3KNTA 4E9EA 4AI5A 1KG6A 1ORPA 2JG6A 2NOBA 1LMZA 4E9FA 1YQRA 1XG7A 5CHZA 2OFKA 1M3QA 2YG8A 3I0XA 3CVSA 1FN7A 3I0WA 1PU8A 2JHJA 3CWAA 3CWTA 1LWVA 1WEIA 5KN8A 4E9GA 3D4VA 2NOLA 1MUYA 1EBMA 3OH6A 5AN4A 1KG7A 4PIIA 3S6IA 1M3HA 4EA4A 1MUDA 5DPKA 3KTUA 3CWUA 1KG5A 4OFHA 1XQOA 1LWYA 2NOZA 1KO9A 3FHFA 3OGDA 2NOIA 1N3AA 4OFEA 4EW0A 4EVVA 1KG4A 4AI4A 4DK9A 1DIZA 4AIAA 4EA5A 2YG9A 1KQJA 4OFAA 2XHIA 2NOHA 3FSPA 1RRQA 4EW4A 1KEAA 1LWWA 4B22A 1WEFA 4B23A 4B24A 3IHOA 1PU6A 2NOEA 2OFIA 1N3CA 1NKUA 1XQPA 3CWSA 1P7MA 1HU0A 2NOFA 1RRSA 4E9HA 1YQMA 1KG2A 2JHNA 3G0QA 1YQLA 3F10A 1P59A 4YPHA 3N0UA 1ORNA 1VRLA 3OH9A 5KN9A 2ABKA 1YQKA
chains in the Genus database with same CATH superfamily
3L2VA 2H56A 3F0ZA 5FROA 4B21A 4BDZA 3CW7A 1PU7A 3OS0A 1PVSA 3N5NX 3OYCA 4YOQA 1MUNA 1U84A 4EJZA 3S3OA 3OYDA 4UOBA 1N39A 4UNFA 4EJYA 2I5WA 1WEGA 3OY9A 3R2XC 3CVTA 4IKFA 2W04A 4BE1A 4HSBA 3FHGA 3OYAA 1KG3A 4E7IA 3IH7A 1MPGA 3OS1A 4YPRA 1NGNA 3KNTA 2V75A 4E9EA 4AI5A 1KG6A 1ORPA 2JG6A 3OYEA 2NOBA 1LMZA 4E9FA 1YQRA 1XG7A 5CHZA 2OFKA 3NNQA 1M3QA 2YG8A 3I0XA 3CVSA 3S3MA 1FN7A 3I0WA 3OYKA 1PU8A 4E7KA 2JHJA 3CWAA 4E7JA 3CWTA 1LWVA 1WEIA 3L2UA 5KN8A 3OYMA 4E9GA 3D4VA 2NOLA 3OS2A 3OYHA 1MUYA 1EBMA 3OH6A 5AN4A 1KG7A 3L2RA 4PIIA 3S6IA 1M3HA 4EA4A 1MUDA 5DPKA 3KTUA 3L2WA 3CWUA 1KG5A 4OFHA 1XQOA 1LWYA 2NOZA 1KO9A 3FHFA 3OGDA 4ZTJA 1N3AA 4OFEA 3L2QA 4EW0A 4EVVA 2NOIA 1KG4A 4AI4A 4DK9A 1DIZA 3OYJA 4AIAA 4EA5A 4BE0A 2YG9A 1KQJA 4BACA 4OFAA 2XHIA 2NOHA 3FSPA 1RRQA 3OYGA 4EW4A 1KEAA 1LWWA 4B22A 4ZTFA 5FRMA 1WEFA 3LCNA 4B24A 4B23A 3IHOA 1PU6A 3VW4A 5FRNA 3OYFA 4NZGA 2NOEA 2OFIA 1N3CA 1NKUA 1XQPA 3OYBA 3OYIA 3CWSA 4E7LA 2JPSA 1P7MA 1HU0A 2NOFA 3OYLA 1RRSA 3OYNA 4E9HA 1YQMA 1KG2A 2JHNA 2W03A 4BDYA 3G0QA 1YQLA 3F10A 4BE2A 4E7HA 4YPHA 3S3NA 1P59A 3N0UA 1ORNA 1VRLA 3OH9A 5KN9A 2ABKA 1YQKA
chains in the Genus database with same CATH topology
2H56A 3F0ZA 4B21A 3CW7A 1PU7A 1PVSA 3N5NX 4YOQA 1MUNA 4EJZA 4UOBA 1N39A 4UNFA 4EJYA 2I5WA 1WEGA 3CVTA 4HSBA 3FHGA 1KG3A 3IH7A 1MPGA 4YPRA 1NGNA 3KNTA 4E9EA 4AI5A 1KG6A 1ORPA 2JG6A 2NOBA 1LMZA 4E9FA 1YQRA 1XG7A 5CHZA 2OFKA 1M3QA 2YG8A 3I0XA 3CVSA 1FN7A 3I0WA 1PU8A 2JHJA 3CWAA 3CWTA 1LWVA 1WEIA 5KN8A 4E9GA 3D4VA 2NOLA 1MUYA 1EBMA 3OH6A 5AN4A 1KG7A 4PIIA 3S6IA 1M3HA 4EA4A 1MUDA 5DPKA 3KTUA 3CWUA 1KG5A 4OFHA 1XQOA 1LWYA 2NOZA 1KO9A 3FHFA 3OGDA 2NOIA 1N3AA 4OFEA 4EW0A 4EVVA 1KG4A 4AI4A 4DK9A 1DIZA 4AIAA 4EA5A 2YG9A 1KQJA 4OFAA 2XHIA 2NOHA 3FSPA 1RRQA 4EW4A 1KEAA 1LWWA 4B22A 1WEFA 4B23A 4B24A 3IHOA 1PU6A 2NOEA 2OFIA 1N3CA 1NKUA 1XQPA 3CWSA 1P7MA 1HU0A 2NOFA 1RRSA 4E9HA 1YQMA 1KG2A 2JHNA 3G0QA 1YQLA 3F10A 1P59A 4YPHA 3N0UA 1ORNA 1VRLA 3OH9A 5KN9A 2ABKA 1YQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H56 A;  3F0Z A;  4B21 A;  3CW7 A;  1PU7 A;  1PVS A;  3N5N X;  4YOQ A;  1MUN A;  4EJZ A;  4UOB A;  1N39 A;  4UNF A;  4EJY A;  2I5W A;  1WEG A;  3CVT A;  4HSB A;  3FHG A;  1KG3 A;  3IH7 A;  1MPG A;  4YPR A;  1NGN A;  3KNT A;  4E9E A;  4AI5 A;  1KG6 A;  1ORP A;  2JG6 A;  2NOB A;  1LMZ A;  4E9F A;  1YQR A;  1XG7 A;  5CHZ A;  2OFK A;  1M3Q A;  2YG8 A;  3I0X A;  3CVS A;  1FN7 A;  3I0W A;  1PU8 A;  2JHJ A;  3CWA A;  3CWT A;  1LWV A;  1WEI A;  5KN8 A;  4E9G A;  3D4V A;  2NOL A;  1MUY A;  1EBM A;  3OH6 A;  5AN4 A;  1KG7 A;  4PII A;  3S6I A;  1M3H A;  4EA4 A;  1MUD A;  5DPK A;  3KTU A;  3CWU A;  1KG5 A;  4OFH A;  1XQO A;  1LWY A;  2NOZ A;  1KO9 A;  3FHF A;  3OGD A;  2NOI A;  1N3A A;  4OFE A;  4EW0 A;  4EVV A;  1KG4 A;  4AI4 A;  4DK9 A;  1DIZ A;  4AIA A;  4EA5 A;  2YG9 A;  1KQJ A;  4OFA A;  2XHI A;  2NOH A;  3FSP A;  1RRQ A;  4EW4 A;  1KEA A;  1LWW A;  4B22 A;  1WEF A;  4B23 A;  4B24 A;  3IHO A;  1PU6 A;  2NOE A;  2OFI A;  1N3C A;  1NKU A;  1XQP A;  3CWS A;  1P7M A;  1HU0 A;  2NOF A;  1RRS A;  4E9H A;  1YQM A;  1KG2 A;  2JHN A;  3G0Q A;  1YQL A;  3F10 A;  1P59 A;  4YPH A;  3N0U A;  1ORN A;  1VRL A;  3OH9 A;  5KN9 A;  2ABK A;  1YQK A; 
#chains in the Genus database with same CATH topology
 3L2V A;  2H56 A;  3F0Z A;  5FRO A;  4B21 A;  4BDZ A;  3CW7 A;  1PU7 A;  3OS0 A;  1PVS A;  3N5N X;  3OYC A;  4YOQ A;  1MUN A;  1U84 A;  4EJZ A;  3S3O A;  3OYD A;  4UOB A;  1N39 A;  4UNF A;  4EJY A;  2I5W A;  1WEG A;  3OY9 A;  3R2X C;  3CVT A;  4IKF A;  2W04 A;  4BE1 A;  4HSB A;  3FHG A;  3OYA A;  1KG3 A;  4E7I A;  3IH7 A;  1MPG A;  3OS1 A;  4YPR A;  1NGN A;  3KNT A;  2V75 A;  4E9E A;  4AI5 A;  1KG6 A;  1ORP A;  2JG6 A;  3OYE A;  2NOB A;  1LMZ A;  4E9F A;  1YQR A;  1XG7 A;  5CHZ A;  2OFK A;  3NNQ A;  1M3Q A;  2YG8 A;  3I0X A;  3CVS A;  3S3M A;  1FN7 A;  3I0W A;  3OYK A;  1PU8 A;  4E7K A;  2JHJ A;  3CWA A;  4E7J A;  3CWT A;  1LWV A;  1WEI A;  3L2U A;  5KN8 A;  3OYM A;  4E9G A;  3D4V A;  2NOL A;  3OS2 A;  3OYH A;  1MUY A;  1EBM A;  3OH6 A;  5AN4 A;  1KG7 A;  3L2R A;  4PII A;  3S6I A;  1M3H A;  4EA4 A;  1MUD A;  5DPK A;  3KTU A;  3L2W A;  3CWU A;  1KG5 A;  4OFH A;  1XQO A;  1LWY A;  2NOZ A;  1KO9 A;  3FHF A;  3OGD A;  4ZTJ A;  1N3A A;  4OFE A;  3L2Q A;  4EW0 A;  4EVV A;  2NOI A;  1KG4 A;  4AI4 A;  4DK9 A;  1DIZ A;  3OYJ A;  4AIA A;  4EA5 A;  4BE0 A;  2YG9 A;  1KQJ A;  4BAC A;  4OFA A;  2XHI A;  2NOH A;  3FSP A;  1RRQ A;  3OYG A;  4EW4 A;  1KEA A;  1LWW A;  4B22 A;  4ZTF A;  5FRM A;  1WEF A;  3LCN A;  4B24 A;  4B23 A;  3IHO A;  1PU6 A;  3VW4 A;  5FRN A;  3OYF A;  4NZG A;  2NOE A;  2OFI A;  1N3C A;  1NKU A;  1XQP A;  3OYB A;  3OYI A;  3CWS A;  4E7L A;  2JPS A;  1P7M A;  1HU0 A;  2NOF A;  3OYL A;  1RRS A;  3OYN A;  4E9H A;  1YQM A;  1KG2 A;  2JHN A;  2W03 A;  4BDY A;  3G0Q A;  1YQL A;  3F10 A;  4BE2 A;  4E7H A;  4YPH A;  3S3N A;  1P59 A;  3N0U A;  1ORN A;  1VRL A;  3OH9 A;  5KN9 A;  2ABK A;  1YQK A; 
#chains in the Genus database with same CATH homology
 2H56 A;  3F0Z A;  4B21 A;  3CW7 A;  1PU7 A;  1PVS A;  3N5N X;  4YOQ A;  1MUN A;  4EJZ A;  4UOB A;  1N39 A;  4UNF A;  4EJY A;  2I5W A;  1WEG A;  3CVT A;  4HSB A;  3FHG A;  1KG3 A;  3IH7 A;  1MPG A;  4YPR A;  1NGN A;  3KNT A;  4E9E A;  4AI5 A;  1KG6 A;  1ORP A;  2JG6 A;  2NOB A;  1LMZ A;  4E9F A;  1YQR A;  1XG7 A;  5CHZ A;  2OFK A;  1M3Q A;  2YG8 A;  3I0X A;  3CVS A;  1FN7 A;  3I0W A;  1PU8 A;  2JHJ A;  3CWA A;  3CWT A;  1LWV A;  1WEI A;  5KN8 A;  4E9G A;  3D4V A;  2NOL A;  1MUY A;  1EBM A;  3OH6 A;  5AN4 A;  1KG7 A;  4PII A;  3S6I A;  1M3H A;  4EA4 A;  1MUD A;  5DPK A;  3KTU A;  3CWU A;  1KG5 A;  4OFH A;  1XQO A;  1LWY A;  2NOZ A;  1KO9 A;  3FHF A;  3OGD A;  2NOI A;  1N3A A;  4OFE A;  4EW0 A;  4EVV A;  1KG4 A;  4AI4 A;  4DK9 A;  1DIZ A;  4AIA A;  4EA5 A;  2YG9 A;  1KQJ A;  4OFA A;  2XHI A;  2NOH A;  3FSP A;  1RRQ A;  4EW4 A;  1KEA A;  1LWW A;  4B22 A;  1WEF A;  4B23 A;  4B24 A;  3IHO A;  1PU6 A;  2NOE A;  2OFI A;  1N3C A;  1NKU A;  1XQP A;  3CWS A;  1P7M A;  1HU0 A;  2NOF A;  1RRS A;  4E9H A;  1YQM A;  1KG2 A;  2JHN A;  3G0Q A;  1YQL A;  3F10 A;  1P59 A;  4YPH A;  3N0U A;  1ORN A;  1VRL A;  3OH9 A;  5KN9 A;  2ABK A;  1YQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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