2JHJA

3-methyladenine dna-glycosylase from archaeoglobus fulgidus
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
295
structure length
290
Chain Sequence
MWRIELKHAVNWELKMKFFVLPELPTPDVVESGVWRRAIVLDGRAVAVMAYPESERTIVVEGNFENREWEAVRRKLVEYLGLQNPEELYRFMDGDEKLRMLKNRFYGFGRAGLMSMSVFEGIAKAIIQQQISFVVAEKLAAKIVGRFGDEVEWNGLKFYGFPTQEAILKAGVEGLRECGLSRRKAELIVEIAKEENLEELKEWGEEEAYEYLTSFKGIGRWTAELVLSMALGKNVFPADDLGVRRAVSRLYFNGEIQSAEKVREIARERFGRFARDILFYLFLYDRFFSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords 3-METHYLADENINE DNA-GLYCOSYLASE
publication title Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
pubmed doi rcsb
source organism Archaeoglobus fulgidus
total genus 102
structure length 290
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2jhjA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2jhjA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 2jhjA01
4E9HA 4OFEA 1VRLA 2OFKA 2NOHA 1WEIA 4EJYA 4E9FA 1KQJA 1KG4A 4B22A 4AIAA 1N3CA 4YPRA 1MUDA 4OFHA 1YQRA 1PVSA 1ORPA 1WEFA 1MUYA 5KN8A 1M3QA 4B24A 3F10A 2ABKA 3G0QA 1RRSA 1PU6A 3CVSA 2XHIA 3S6IA 1YQKA 3OH6A 3CWUA 1N39A 5KN9A 1RRQA 2NOLA 3D4VA 4HSBA 1YQLA 1FN7A 1P7MA 2NOZA 1KG6A 1LWWA 4E9GA 1EBMA 4B21A 4DK9A 2JHNA 3I0XA 3OGDA 1MPGA 4PIIA 3OH9A 4UNFA 4OFAA 2YG8A 4EW4A 4EJZA 1NKUA 1LWYA 3IH7A 3N0UA 4YOQA 4EVVA 1N3AA 4E9EA 1MUNA 1KG3A 2NOEA 2NOIA 1ORNA 5CHZA 1KO9A 2JHJA 1M3HA 2NOFA 1KEAA 1PU8A 3FSPA 2I5WA 3CW7A 3IHOA 3KTUA 3CVTA 2JG6A 3FHGA 3CWAA 1KG7A 4AI4A 4YPHA 2OFIA 1KG2A 1P59A 4EA4A 1DIZA 4B23A 3CWTA 1KG5A 1XG7A 3N5NX 1XQOA 1XQPA 3KNTA 5DPKA 4EA5A 3F0ZA 2YG9A 1HU0A 1PU7A 5AN4A 2NOBA 3I0WA 2H56A 1LWVA 1WEGA 3CWSA 1YQMA 1NGNA 1LMZA 4EW0A 4UOBA 3FHFA 4AI5A
chains in the Genus database with same CATH superfamily
3OS0A 1T6AA 1NH2A 4EJYA 1KFIA 3HS9A 4MRQA 3OYJA 2FKFA 3EIKA 1J3MA 2IV8A 2W03A 3OYBA 1MUDA 3DPTA 4BE0A 4D7RA 5KL0A 5KN8A 4HJHA 4BE1A 3OYHA 1U84A 5F9CA 1RRSA 2JOIA 2FGTA 3ENOC 1QNBA 1K35A 2HZSA 3CWUA 4WXAA 4DULA 5KN9A 1RRQA 3I3WA 1FN7A 2MJ7A 1KYDA 4E9GA 4DK9A 2Y8QA 4EALA 4ROCB 1QNCA 4D7QA 2FUVA 4UNFA 1EUVA 1QNEA 3L2VA 1NKUA 2JPSA 2D0BA 1KG3A 1YTBA 2ZFDB 2NOEA 2FKMX 3T4NA 1ORNA 1QN5A 2Z0FA 2W04A 2H5AX 4E7KA 4Q11A 1KEAA 3KTUA 3CVTA 3L2RA 4E7IA 4AI4A 4YPHA 1K2YX 3OS1A 2OFIA 3NA5A 1TBAB 1JFIC 3D7QA 3OSEA 2Z8UA 3OYNA 1XQPA 3F0ZA 4IKFA 5AN4A 3I0WA 2H56A 3CWSA 2IV9A 1VOKA 1QN6A 4EW0A 1VTOA 4AI5A 1PCZA 4E9HA 4OFEA 1VRLA 1KYFA 1WEIA 4E9FA 1M5Q1 1KG4A 3RPJA 3HS8A 1V5SA 4YPRA 2QLVA 1KY6A 5JMVD 1D3UA 3EAYA 1WEFA 1TUOA 1MUYA 1M3QA 2D0CA 1C4GA 1PZDA 2H4LX 4B24A 2XHIA 2DKAA 3S6IA 1QN3A 1YQKA 2G30A 3OH6A 4I8OA 1VTLE 1P7MA 3OYDA 5BMNA 1LWWA 1LXTA 1EBMA 1QNAA 1YTFA 2LAEA 1QTPA 2F7LA 2PWWA 3OH9A 5FRNA 2YG8A 4BDZA 3DPUA 2R5XA 2HL8A 2YA3A 4YOQA 2QRDA 2OOYA 2QREA 2Y8LA 3OC3C 1E42A 3ENCA 3RSMA 4C7PA 3UW2A 3BKQX 1QN7A 2VJ0A 1UT4A 1WQAA 4ROEB 3CW7A 4E7HA 1XSZA 2JG6A 3FHGA 1C9BB 1KG7A 3C04A 1KY7A 2D0AA 4NZGA 3CWTA 1XG7A 1CDWA 4ZTJA 2QR1A 1RM1A 1HU0A 1PU7A 2NLVA 1LWVA 1WEGA 3OY9A 1NGNA 3OYKA 3PDKA 3OYLA 1KG5A 1UT7A 2V92A 2OFKA 2NOHA 3VW4A 1KQJA 4B22A 4AIAA 4E7JA 1NVPA 4EAGA 1JDYA 4RODB 1C47A 1QN4A 3F10A 4CFFA 1PU6A 3OYCA 2O3OA 1N39A 2NOLA 4BACA 3D4VA 1UL7A 4HSBA 1YQLA 1KG6A 2DKDA 3VN5A 1QTSA 1MP9A 4B21A 1P5GX 2JHNA 3I0XA 4WZSD 1MPGA 4OFAA 2DKCA 4EAJA 3IH7A 3N0UA 3OSTA 4EVVA 1N3AA 3OYMA 2EHBD 4BE2A 3H1ZA 2NOIA 2HKPA 3OYGA 2YH5A 5CHZA 1M3HA 2NOFA 1PU8A 1VKLA 2MZ8A 1TBPA 1PCJX 4EAIA 3NNQA 5EPCA 1QN9A 3OSMA 1KG2A 1P59A 1DIZA 1WJWA 4PY5A 5FROA 3SNSA 2V75A 1XQOA 3L2UA 3OS2A 5DPKA 2NWVA 2HZMA 4ZTFA 3OYAA 2YG9A 2NOBA 5JN5A 4BJUA 5IYCP 5FRMA 4TPSA 4EAKA 1LMZA 2QRCA 4UOBA 3FHFA 1KYUA 2HL9A 3S3MA 3KRMA 1N3CA 3ULXA 3OYFA 1R4XA 1NGMA 4OFHA 1YQRA 1PVSA 1ORPA 1QN8A 2JPIA 3N89A 2ABKA 3G0QA 3LCNA 3TE5A 3ASMA 3CVSA 4B0AA 3OCIA 3S3NA 4IL8A 2NOZA 1Q9UA 1AISA 2NVMA 3PMGA 1TGHA 3OGDA 3L2WA 5HSHA 4PIIA 4EW4A 1W80A 4EJZA 4QG5A 1LWYA 3OLPA 4E9EA 1MUNA 3L2QA 3TDHA 5IYBP 2OOXA 3OYIA 1KO9A 2JHJA 4BDYA 1PCMX 3FSPA 4WX8A 2I5WA 3IHOA 1KFQA 3CWAA 3OYEA 4EA4A 4B23A 3S3OA 3R2XC 1P5DX 1VOLB 3N5NX 2V8QA 3KNTA 4EA5A 1B9KA 5BMPA 4E7LA 5IYDP 1YQMA 2V9JA
chains in the Genus database with same CATH topology
4E9HA 4OFEA 1VRLA 2OFKA 2NOHA 1WEIA 4EJYA 4E9FA 1KQJA 1KG4A 4B22A 4AIAA 1N3CA 4YPRA 1MUDA 4OFHA 1YQRA 1PVSA 1ORPA 1WEFA 1MUYA 5KN8A 1M3QA 4B24A 3F10A 2ABKA 3G0QA 1RRSA 1PU6A 3CVSA 2XHIA 3S6IA 1YQKA 3OH6A 3CWUA 1N39A 5KN9A 1RRQA 2NOLA 3D4VA 4HSBA 1YQLA 1FN7A 1P7MA 2NOZA 1KG6A 1LWWA 4E9GA 1EBMA 4B21A 4DK9A 2JHNA 3I0XA 3OGDA 1MPGA 4PIIA 3OH9A 4UNFA 4OFAA 2YG8A 4EW4A 4EJZA 1NKUA 1LWYA 3IH7A 3N0UA 4YOQA 4EVVA 1N3AA 4E9EA 1MUNA 1KG3A 2NOEA 2NOIA 1ORNA 5CHZA 1KO9A 2JHJA 1M3HA 2NOFA 1KEAA 1PU8A 3FSPA 2I5WA 3CW7A 3IHOA 3KTUA 3CVTA 2JG6A 3FHGA 3CWAA 1KG7A 4AI4A 4YPHA 2OFIA 1KG2A 1P59A 4EA4A 1DIZA 4B23A 3CWTA 1KG5A 1XG7A 3N5NX 1XQOA 1XQPA 3KNTA 5DPKA 4EA5A 3F0ZA 2YG9A 1HU0A 1PU7A 5AN4A 2NOBA 3I0WA 2H56A 1LWVA 1WEGA 3CWSA 1YQMA 1NGNA 1LMZA 4EW0A 4UOBA 3FHFA 4AI5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E9H A;  4OFE A;  1VRL A;  2OFK A;  2NOH A;  1WEI A;  4EJY A;  4E9F A;  1KQJ A;  1KG4 A;  4B22 A;  4AIA A;  1N3C A;  4YPR A;  1MUD A;  4OFH A;  1YQR A;  1PVS A;  1ORP A;  1WEF A;  1MUY A;  5KN8 A;  1M3Q A;  4B24 A;  3F10 A;  2ABK A;  3G0Q A;  1RRS A;  1PU6 A;  3CVS A;  2XHI A;  3S6I A;  1YQK A;  3OH6 A;  3CWU A;  1N39 A;  5KN9 A;  1RRQ A;  2NOL A;  3D4V A;  4HSB A;  1YQL A;  1FN7 A;  1P7M A;  2NOZ A;  1KG6 A;  1LWW A;  4E9G A;  1EBM A;  4B21 A;  4DK9 A;  2JHN A;  3I0X A;  3OGD A;  1MPG A;  4PII A;  3OH9 A;  4UNF A;  4OFA A;  2YG8 A;  4EW4 A;  4EJZ A;  1NKU A;  1LWY A;  3IH7 A;  3N0U A;  4YOQ A;  4EVV A;  1N3A A;  4E9E A;  1MUN A;  1KG3 A;  2NOE A;  2NOI A;  1ORN A;  5CHZ A;  1KO9 A;  2JHJ A;  1M3H A;  2NOF A;  1KEA A;  1PU8 A;  3FSP A;  2I5W A;  3CW7 A;  3IHO A;  3KTU A;  3CVT A;  2JG6 A;  3FHG A;  3CWA A;  1KG7 A;  4AI4 A;  4YPH A;  2OFI A;  1KG2 A;  1P59 A;  4EA4 A;  1DIZ A;  4B23 A;  3CWT A;  1KG5 A;  1XG7 A;  3N5N X;  1XQO A;  1XQP A;  3KNT A;  5DPK A;  4EA5 A;  3F0Z A;  2YG9 A;  1HU0 A;  1PU7 A;  5AN4 A;  2NOB A;  3I0W A;  2H56 A;  1LWV A;  1WEG A;  3CWS A;  1YQM A;  1NGN A;  1LMZ A;  4EW0 A;  4UOB A;  3FHF A;  4AI5 A; 
#chains in the Genus database with same CATH topology
 3OS0 A;  1T6A A;  1NH2 A;  4EJY A;  1KFI A;  3HS9 A;  4MRQ A;  3OYJ A;  2FKF A;  3EIK A;  1J3M A;  2IV8 A;  2W03 A;  3OYB A;  1MUD A;  3DPT A;  4BE0 A;  4D7R A;  5KL0 A;  5KN8 A;  4HJH A;  4BE1 A;  3OYH A;  1U84 A;  5F9C A;  1RRS A;  2JOI A;  2FGT A;  3ENO C;  1QNB A;  1K35 A;  2HZS A;  3CWU A;  4WXA A;  4DUL A;  5KN9 A;  1RRQ A;  3I3W A;  1FN7 A;  2MJ7 A;  1KYD A;  4E9G A;  4DK9 A;  2Y8Q A;  4EAL A;  4ROC B;  1QNC A;  4D7Q A;  2FUV A;  4UNF A;  1EUV A;  1QNE A;  3L2V A;  1NKU A;  2JPS A;  2D0B A;  1KG3 A;  1YTB A;  2ZFD B;  2NOE A;  2FKM X;  3T4N A;  1ORN A;  1QN5 A;  2Z0F A;  2W04 A;  2H5A X;  4E7K A;  4Q11 A;  1KEA A;  3KTU A;  3CVT A;  3L2R A;  4E7I A;  4AI4 A;  4YPH A;  1K2Y X;  3OS1 A;  2OFI A;  3NA5 A;  1TBA B;  1JFI C;  3D7Q A;  3OSE A;  2Z8U A;  3OYN A;  1XQP A;  3F0Z A;  4IKF A;  5AN4 A;  3I0W A;  2H56 A;  3CWS A;  2IV9 A;  1VOK A;  1QN6 A;  4EW0 A;  1VTO A;  4AI5 A;  1PCZ A;  4E9H A;  4OFE A;  1VRL A;  1KYF A;  1WEI A;  4E9F A;  1M5Q 1;  1KG4 A;  3RPJ A;  3HS8 A;  1V5S A;  4YPR A;  2QLV A;  1KY6 A;  5JMV D;  1D3U A;  3EAY A;  1WEF A;  1TUO A;  1MUY A;  1M3Q A;  2D0C A;  1C4G A;  1PZD A;  2H4L X;  4B24 A;  2XHI A;  2DKA A;  3S6I A;  1QN3 A;  1YQK A;  2G30 A;  3OH6 A;  4I8O A;  1VTL E;  1P7M A;  3OYD A;  5BMN A;  1LWW A;  1LXT A;  1EBM A;  1QNA A;  1YTF A;  2LAE A;  1QTP A;  2F7L A;  2PWW A;  3OH9 A;  5FRN A;  2YG8 A;  4BDZ A;  3DPU A;  2R5X A;  2HL8 A;  2YA3 A;  4YOQ A;  2QRD A;  2OOY A;  2QRE A;  2Y8L A;  3OC3 C;  1E42 A;  3ENC A;  3RSM A;  4C7P A;  3UW2 A;  3BKQ X;  1QN7 A;  2VJ0 A;  1UT4 A;  1WQA A;  4ROE B;  3CW7 A;  4E7H A;  1XSZ A;  2JG6 A;  3FHG A;  1C9B B;  1KG7 A;  3C04 A;  1KY7 A;  2D0A A;  4NZG A;  3CWT A;  1XG7 A;  1CDW A;  4ZTJ A;  2QR1 A;  1RM1 A;  1HU0 A;  1PU7 A;  2NLV A;  1LWV A;  1WEG A;  3OY9 A;  1NGN A;  3OYK A;  3PDK A;  3OYL A;  1KG5 A;  1UT7 A;  2V92 A;  2OFK A;  2NOH A;  3VW4 A;  1KQJ A;  4B22 A;  4AIA A;  4E7J A;  1NVP A;  4EAG A;  1JDY A;  4ROD B;  1C47 A;  1QN4 A;  3F10 A;  4CFF A;  1PU6 A;  3OYC A;  2O3O A;  1N39 A;  2NOL A;  4BAC A;  3D4V A;  1UL7 A;  4HSB A;  1YQL A;  1KG6 A;  2DKD A;  3VN5 A;  1QTS A;  1MP9 A;  4B21 A;  1P5G X;  2JHN A;  3I0X A;  4WZS D;  1MPG A;  4OFA A;  2DKC A;  4EAJ A;  3IH7 A;  3N0U A;  3OST A;  4EVV A;  1N3A A;  3OYM A;  2EHB D;  4BE2 A;  3H1Z A;  2NOI A;  2HKP A;  3OYG A;  2YH5 A;  5CHZ A;  1M3H A;  2NOF A;  1PU8 A;  1VKL A;  2MZ8 A;  1TBP A;  1PCJ X;  4EAI A;  3NNQ A;  5EPC A;  1QN9 A;  3OSM A;  1KG2 A;  1P59 A;  1DIZ A;  1WJW A;  4PY5 A;  5FRO A;  3SNS A;  2V75 A;  1XQO A;  3L2U A;  3OS2 A;  5DPK A;  2NWV A;  2HZM A;  4ZTF A;  3OYA A;  2YG9 A;  2NOB A;  5JN5 A;  4BJU A;  5IYC P;  5FRM A;  4TPS A;  4EAK A;  1LMZ A;  2QRC A;  4UOB A;  3FHF A;  1KYU A;  2HL9 A;  3S3M A;  3KRM A;  1N3C A;  3ULX A;  3OYF A;  1R4X A;  1NGM A;  4OFH A;  1YQR A;  1PVS A;  1ORP A;  1QN8 A;  2JPI A;  3N89 A;  2ABK A;  3G0Q A;  3LCN A;  3TE5 A;  3ASM A;  3CVS A;  4B0A A;  3OCI A;  3S3N A;  4IL8 A;  2NOZ A;  1Q9U A;  1AIS A;  2NVM A;  3PMG A;  1TGH A;  3OGD A;  3L2W A;  5HSH A;  4PII A;  4EW4 A;  1W80 A;  4EJZ A;  4QG5 A;  1LWY A;  3OLP A;  4E9E A;  1MUN A;  3L2Q A;  3TDH A;  5IYB P;  2OOX A;  3OYI A;  1KO9 A;  2JHJ A;  4BDY A;  1PCM X;  3FSP A;  4WX8 A;  2I5W A;  3IHO A;  1KFQ A;  3CWA A;  3OYE A;  4EA4 A;  4B23 A;  3S3O A;  3R2X C;  1P5D X;  1VOL B;  3N5N X;  2V8Q A;  3KNT A;  4EA5 A;  1B9K A;  5BMP A;  4E7L A;  5IYD P;  1YQM A;  2V9J A; 
#chains in the Genus database with same CATH homology
 4E9H A;  4OFE A;  1VRL A;  2OFK A;  2NOH A;  1WEI A;  4EJY A;  4E9F A;  1KQJ A;  1KG4 A;  4B22 A;  4AIA A;  1N3C A;  4YPR A;  1MUD A;  4OFH A;  1YQR A;  1PVS A;  1ORP A;  1WEF A;  1MUY A;  5KN8 A;  1M3Q A;  4B24 A;  3F10 A;  2ABK A;  3G0Q A;  1RRS A;  1PU6 A;  3CVS A;  2XHI A;  3S6I A;  1YQK A;  3OH6 A;  3CWU A;  1N39 A;  5KN9 A;  1RRQ A;  2NOL A;  3D4V A;  4HSB A;  1YQL A;  1FN7 A;  1P7M A;  2NOZ A;  1KG6 A;  1LWW A;  4E9G A;  1EBM A;  4B21 A;  4DK9 A;  2JHN A;  3I0X A;  3OGD A;  1MPG A;  4PII A;  3OH9 A;  4UNF A;  4OFA A;  2YG8 A;  4EW4 A;  4EJZ A;  1NKU A;  1LWY A;  3IH7 A;  3N0U A;  4YOQ A;  4EVV A;  1N3A A;  4E9E A;  1MUN A;  1KG3 A;  2NOE A;  2NOI A;  1ORN A;  5CHZ A;  1KO9 A;  2JHJ A;  1M3H A;  2NOF A;  1KEA A;  1PU8 A;  3FSP A;  2I5W A;  3CW7 A;  3IHO A;  3KTU A;  3CVT A;  2JG6 A;  3FHG A;  3CWA A;  1KG7 A;  4AI4 A;  4YPH A;  2OFI A;  1KG2 A;  1P59 A;  4EA4 A;  1DIZ A;  4B23 A;  3CWT A;  1KG5 A;  1XG7 A;  3N5N X;  1XQO A;  1XQP A;  3KNT A;  5DPK A;  4EA5 A;  3F0Z A;  2YG9 A;  1HU0 A;  1PU7 A;  5AN4 A;  2NOB A;  3I0W A;  2H56 A;  1LWV A;  1WEG A;  3CWS A;  1YQM A;  1NGN A;  1LMZ A;  4EW0 A;  4UOB A;  3FHF A;  4AI5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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