2JHJA

3-methyladenine dna-glycosylase from archaeoglobus fulgidus
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
295
structure length
290
Chain Sequence
MWRIELKHAVNWELKMKFFVLPELPTPDVVESGVWRRAIVLDGRAVAVMAYPESERTIVVEGNFENREWEAVRRKLVEYLGLQNPEELYRFMDGDEKLRMLKNRFYGFGRAGLMSMSVFEGIAKAIIQQQISFVVAEKLAAKIVGRFGDEVEWNGLKFYGFPTQEAILKAGVEGLRECGLSRRKAELIVEIAKEENLEELKEWGEEEAYEYLTSFKGIGRWTAELVLSMALGKNVFPADDLGVRRAVSRLYFNGEIQSAEKVREIARERFGRFARDILFYLFLYDRFFSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 3-METHYLADENINE DNA-GLYCOSYLASE
publication title Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
pubmed doi rcsb
source organism Archaeoglobus fulgidus
molecule tags Hydrolase
total genus 102
structure length 290
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2jhjA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2jhjA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 2jhjA01
1PVSA 5CHZA 4YPHA 3FHGA 3OH6A 3D4VA 4EA4A 4UOBA 3OH9A 3CWUA 1PU8A 4AI4A 4AIAA 1WEFA 1LWWA 3F10A 4E9HA 2NOHA 3KTUA 4DK9A 1YQRA 1PU6A 1HU0A 3CVSA 2YG9A 5AN4A 1ORPA 2NOIA 1N39A 1DIZA 1KG7A 3N0UA 1WEGA 3OGDA 1MPGA 4PIIA 4EW0A 3FSPA 1XQOA 1KG5A 4EVVA 1KG6A 2NOEA 1RRQA 1XG7A 2OFIA 1RRSA 1XQPA 1KG2A 4E9GA 5KN9A 5KN8A 1PU7A 2NOBA 3CVTA 1ORNA 2NOLA 4B21A 2NOZA 3IH7A 3CWAA 4B22A 4B23A 4YPRA 4YOQA 3CWSA 4OFAA 3G0QA 4AI5A 1KQJA 1P7MA 3IHOA 2JHJA 2H56A 2NOFA 1NKUA 3FHFA 2XHIA 3I0XA 4E9EA 4EA5A 1WEIA 1KG3A 3KNTA 4OFHA 4B24A 1NGNA 1LWYA 1MUDA 3F0ZA 4HSBA 1P59A 2OFKA 3S6IA 1EBMA 1KEAA 1LWVA 1N3AA 2YG8A 1YQMA 1MUNA 3I0WA 1KG4A 1LMZA 4UNFA 2ABKA 5DPKA 1N3CA 2JG6A 3CWTA 1M3HA 1M3QA 4E9FA 2I5WA 4OFEA 1YQLA 2JHNA 4EW4A 3N5NX 1KO9A 1MUYA 4EJYA 1VRLA 1YQKA 4EJZA 1FN7A 3CW7A
chains in the Genus database with same CATH superfamily
1PVSA 5CHZA 3OS0A 3OCIA 2NLVA 5IYCP 3D4VA 3OH9A 3CWUA 4AI4A 1WEFA 3F10A 1QN7A 1PU6A 3VN5A 2LAEA 5AN4A 1N39A 1DIZA 3OGDA 2PWWA 1EUVA 4EW0A 4NZGA 3FSPA 2FKMX 3EAYA 4BE0A 1XQOA 4EVVA 1XG7A 2OFIA 2D0CA 1CDWA 1QN8A 3LCNA 3OYJA 3OC3C 1KYFA 4B21A 3IH7A 4YOQA 1UT4A 2FUVA 2HKPA 2QRCA 3G0QA 4EAKA 4PY5A 3UW2A 3R2XC 2H56A 2NOFA 2Y8QA 2FGTA 3ULXA 5JMVD 3N89A 2VJ0A 1NVPA 1KFQA 4RODB 4Q11A 4E7HA 1WEIA 1PCJX 4E7KA 1MUDA 3S6IA 3TDHA 4CFFA 1M3QA 3EIKA 2I5WA 4OFEA 4IL8A 1YQLA 1MUYA 3ENOC 3NNQA 2O3OA 1YQKA 4EJZA 3CW7A 4YPHA 4EAGA 4E7IA 4BDYA 3L2QA 4AIAA 3OYNA 1T6AA 4HJHA 1YTFA 2QREA 3VW4A 3OYAA 3S3MA 3CVSA 2YG9A 1ORPA 5FRMA 3PMGA 1WEGA 4ROEB 3L2RA 3OYDA 1PCZA 2ZFDB 1VTOA 3NA5A 1KFIA 1KG5A 1RRQA 2Y8LA 1UL7A 1XSZA 1UT7A 3CVTA 2NOBA 1JFIC 3CWAA 4B22A 3TE5A 3OS1A 1QNBA 1TBAB 4YPRA 3L2UA 3ENCA 3CWSA 3OYHA 3D7QA 4EAIA 4BDZA 4DULA 4AI5A 1Q9UA 2W04A 5BMPA 3IHOA 2JHJA 4ZTFA 5FROA 2HZSA 2DKCA 3T4NA 3OYFA 2QLVA 1TGHA 2JPIA 1P5DX 1KYUA 1QNAA 2G30A 3KNTA 2HL9A 2YA3A 3L2WA 4HSBA 4E7LA 1P59A 1QN9A 1QN6A 1KEAA 2OOXA 1N3AA 2YG8A 1YQMA 4UNFA 1LMZA 2IV9A 5JN5A 2JG6A 3CWTA 1M3HA 4BE2A 1NGMA 1PZDA 2DKAA 4BE1A 3OLPA 4EAJA 3ASMA 4EW4A 4D7RA 2V9JA 1KO9A 1VOLB 4EJYA 3OSMA 1E42A 3FHGA 3OYKA 3OH6A 2V75A 5IYDP 3KRMA 2Z0FA 1J3MA 1QN5A 3I3WA 2MJ7A 4E9HA 1HU0A 3H1ZA 1C4GA 1V5SA 2QRDA 4B0AA 1KG7A 2D0AA 2QR1A 3PDKA 1P5GX 1NH2A 1C47A 1QNEA 1KG6A 1WJWA 1KY6A 1RRSA 2JPSA 4MRQA 2HL8A 4E9GA 3DPTA 5KN8A 1PU7A 1QN3A 1ORNA 5BMNA 2NOZA 5EPCA 4B23A 1PCMX 4OFAA 1D3UA 3OY9A 3OYBA 1KQJA 1B9KA 3L2VA 1TUOA 2DKDA 4WX8A 2XHIA 3C04A 3I0XA 1M5Q1 4E9EA 3RPJA 5HSHA 1KG3A 1TBPA 1K2YX 4QG5A 4OFHA 4ZTJA 1NGNA 1YTBA 4WXAA 1LWYA 3F0ZA 1LXTA 1EBMA 3S3NA 3I0WA 1KG4A 3OYEA 2ABKA 3DPUA 4BACA 3OYCA 3BKQX 1VOKA 4E9FA 2D0BA 2JHNA 3N5NX 3OYIA 2H4LX 1FN7A 1R4XA 2OOYA 4TPSA 4EA4A 4UOBA 1PU8A 1AISA 4I8OA 2JOIA 2HZMA 1LWWA 1VKLA 2IV8A 2NOHA 3KTUA 4DK9A 1YQRA 1W80A 3OYMA 5FRNA 2NOIA 2F7LA 2V8QA 3N0UA 1MPGA 4PIIA 2V92A 1VTLE 1K35A 1KYDA 1QNCA 1QTPA 4E7JA 2NOEA 2W03A 2H5AX 4BJUA 1XQPA 1KG2A 5KN9A 1U84A 3OYLA 1RM1A 2NOLA 4EALA 2FKFA 3S3OA 1WQAA 3OYGA 3OS2A 4D7QA 4WZSD 2MZ8A 1P7MA 3HS8A 1NKUA 3FHFA 3OSEA 2EHBD 4EA5A 1QTSA 2YH5A 4B24A 5KL0A 1MP9A 4IKFA 1C9BB 3SNSA 2NWVA 2OFKA 5F9CA 2NVMA 1JDYA 1LWVA 5IYBP 1MUNA 2Z8UA 5DPKA 1N3CA 1KY7A 4C7PA 3RSMA 4ROCB 3OSTA 1QN4A 1VRLA 2R5XA 3HS9A
chains in the Genus database with same CATH topology
1PVSA 5CHZA 4YPHA 3FHGA 3OH6A 3D4VA 4EA4A 4UOBA 3OH9A 3CWUA 1PU8A 4AI4A 4AIAA 1WEFA 1LWWA 3F10A 4E9HA 2NOHA 3KTUA 4DK9A 1YQRA 1PU6A 1HU0A 3CVSA 2YG9A 5AN4A 1ORPA 2NOIA 1N39A 1DIZA 1KG7A 3N0UA 1WEGA 3OGDA 1MPGA 4PIIA 4EW0A 3FSPA 1XQOA 1KG5A 4EVVA 1KG6A 2NOEA 1RRQA 1XG7A 2OFIA 1RRSA 1XQPA 1KG2A 4E9GA 5KN9A 5KN8A 1PU7A 2NOBA 3CVTA 1ORNA 2NOLA 4B21A 2NOZA 3IH7A 3CWAA 4B22A 4B23A 4YPRA 4YOQA 3CWSA 4OFAA 3G0QA 4AI5A 1KQJA 1P7MA 3IHOA 2JHJA 2H56A 2NOFA 1NKUA 3FHFA 2XHIA 3I0XA 4E9EA 4EA5A 1WEIA 1KG3A 3KNTA 4OFHA 4B24A 1NGNA 1LWYA 1MUDA 3F0ZA 4HSBA 1P59A 2OFKA 3S6IA 1EBMA 1KEAA 1LWVA 1N3AA 2YG8A 1YQMA 1MUNA 3I0WA 1KG4A 1LMZA 4UNFA 2ABKA 5DPKA 1N3CA 2JG6A 3CWTA 1M3HA 1M3QA 4E9FA 2I5WA 4OFEA 1YQLA 2JHNA 4EW4A 3N5NX 1KO9A 1MUYA 4EJYA 1VRLA 1YQKA 4EJZA 1FN7A 3CW7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PVS A;  5CHZ A;  4YPH A;  3FHG A;  3OH6 A;  3D4V A;  4EA4 A;  4UOB A;  3OH9 A;  3CWU A;  1PU8 A;  4AI4 A;  4AIA A;  1WEF A;  1LWW A;  3F10 A;  4E9H A;  2NOH A;  3KTU A;  4DK9 A;  1YQR A;  1PU6 A;  1HU0 A;  3CVS A;  2YG9 A;  5AN4 A;  1ORP A;  2NOI A;  1N39 A;  1DIZ A;  1KG7 A;  3N0U A;  1WEG A;  3OGD A;  1MPG A;  4PII A;  4EW0 A;  3FSP A;  1XQO A;  1KG5 A;  4EVV A;  1KG6 A;  2NOE A;  1RRQ A;  1XG7 A;  2OFI A;  1RRS A;  1XQP A;  1KG2 A;  4E9G A;  5KN9 A;  5KN8 A;  1PU7 A;  2NOB A;  3CVT A;  1ORN A;  2NOL A;  4B21 A;  2NOZ A;  3IH7 A;  3CWA A;  4B22 A;  4B23 A;  4YPR A;  4YOQ A;  3CWS A;  4OFA A;  3G0Q A;  4AI5 A;  1KQJ A;  1P7M A;  3IHO A;  2JHJ A;  2H56 A;  2NOF A;  1NKU A;  3FHF A;  2XHI A;  3I0X A;  4E9E A;  4EA5 A;  1WEI A;  1KG3 A;  3KNT A;  4OFH A;  4B24 A;  1NGN A;  1LWY A;  1MUD A;  3F0Z A;  4HSB A;  1P59 A;  2OFK A;  3S6I A;  1EBM A;  1KEA A;  1LWV A;  1N3A A;  2YG8 A;  1YQM A;  1MUN A;  3I0W A;  1KG4 A;  1LMZ A;  4UNF A;  2ABK A;  5DPK A;  1N3C A;  2JG6 A;  3CWT A;  1M3H A;  1M3Q A;  4E9F A;  2I5W A;  4OFE A;  1YQL A;  2JHN A;  4EW4 A;  3N5N X;  1KO9 A;  1MUY A;  4EJY A;  1VRL A;  1YQK A;  4EJZ A;  1FN7 A;  3CW7 A; 
#chains in the Genus database with same CATH topology
 1PVS A;  5CHZ A;  3OS0 A;  3OCI A;  2NLV A;  5IYC P;  3D4V A;  3OH9 A;  3CWU A;  4AI4 A;  1WEF A;  3F10 A;  1QN7 A;  1PU6 A;  3VN5 A;  2LAE A;  5AN4 A;  1N39 A;  1DIZ A;  3OGD A;  2PWW A;  1EUV A;  4EW0 A;  4NZG A;  3FSP A;  2FKM X;  3EAY A;  4BE0 A;  1XQO A;  4EVV A;  1XG7 A;  2OFI A;  2D0C A;  1CDW A;  1QN8 A;  3LCN A;  3OYJ A;  3OC3 C;  1KYF A;  4B21 A;  3IH7 A;  4YOQ A;  1UT4 A;  2FUV A;  2HKP A;  2QRC A;  3G0Q A;  4EAK A;  4PY5 A;  3UW2 A;  3R2X C;  2H56 A;  2NOF A;  2Y8Q A;  2FGT A;  3ULX A;  5JMV D;  3N89 A;  2VJ0 A;  1NVP A;  1KFQ A;  4ROD B;  4Q11 A;  4E7H A;  1WEI A;  1PCJ X;  4E7K A;  1MUD A;  3S6I A;  3TDH A;  4CFF A;  1M3Q A;  3EIK A;  2I5W A;  4OFE A;  4IL8 A;  1YQL A;  1MUY A;  3ENO C;  3NNQ A;  2O3O A;  1YQK A;  4EJZ A;  3CW7 A;  4YPH A;  4EAG A;  4E7I A;  4BDY A;  3L2Q A;  4AIA A;  3OYN A;  1T6A A;  4HJH A;  1YTF A;  2QRE A;  3VW4 A;  3OYA A;  3S3M A;  3CVS A;  2YG9 A;  1ORP A;  5FRM A;  3PMG A;  1WEG A;  4ROE B;  3L2R A;  3OYD A;  1PCZ A;  2ZFD B;  1VTO A;  3NA5 A;  1KFI A;  1KG5 A;  1RRQ A;  2Y8L A;  1UL7 A;  1XSZ A;  1UT7 A;  3CVT A;  2NOB A;  1JFI C;  3CWA A;  4B22 A;  3TE5 A;  3OS1 A;  1QNB A;  1TBA B;  4YPR A;  3L2U A;  3ENC A;  3CWS A;  3OYH A;  3D7Q A;  4EAI A;  4BDZ A;  4DUL A;  4AI5 A;  1Q9U A;  2W04 A;  5BMP A;  3IHO A;  2JHJ A;  4ZTF A;  5FRO A;  2HZS A;  2DKC A;  3T4N A;  3OYF A;  2QLV A;  1TGH A;  2JPI A;  1P5D X;  1KYU A;  1QNA A;  2G30 A;  3KNT A;  2HL9 A;  2YA3 A;  3L2W A;  4HSB A;  4E7L A;  1P59 A;  1QN9 A;  1QN6 A;  1KEA A;  2OOX A;  1N3A A;  2YG8 A;  1YQM A;  4UNF A;  1LMZ A;  2IV9 A;  5JN5 A;  2JG6 A;  3CWT A;  1M3H A;  4BE2 A;  1NGM A;  1PZD A;  2DKA A;  4BE1 A;  3OLP A;  4EAJ A;  3ASM A;  4EW4 A;  4D7R A;  2V9J A;  1KO9 A;  1VOL B;  4EJY A;  3OSM A;  1E42 A;  3FHG A;  3OYK A;  3OH6 A;  2V75 A;  5IYD P;  3KRM A;  2Z0F A;  1J3M A;  1QN5 A;  3I3W A;  2MJ7 A;  4E9H A;  1HU0 A;  3H1Z A;  1C4G A;  1V5S A;  2QRD A;  4B0A A;  1KG7 A;  2D0A A;  2QR1 A;  3PDK A;  1P5G X;  1NH2 A;  1C47 A;  1QNE A;  1KG6 A;  1WJW A;  1KY6 A;  1RRS A;  2JPS A;  4MRQ A;  2HL8 A;  4E9G A;  3DPT A;  5KN8 A;  1PU7 A;  1QN3 A;  1ORN A;  5BMN A;  2NOZ A;  5EPC A;  4B23 A;  1PCM X;  4OFA A;  1D3U A;  3OY9 A;  3OYB A;  1KQJ A;  1B9K A;  3L2V A;  1TUO A;  2DKD A;  4WX8 A;  2XHI A;  3C04 A;  3I0X A;  1M5Q 1;  4E9E A;  3RPJ A;  5HSH A;  1KG3 A;  1TBP A;  1K2Y X;  4QG5 A;  4OFH A;  4ZTJ A;  1NGN A;  1YTB A;  4WXA A;  1LWY A;  3F0Z A;  1LXT A;  1EBM A;  3S3N A;  3I0W A;  1KG4 A;  3OYE A;  2ABK A;  3DPU A;  4BAC A;  3OYC A;  3BKQ X;  1VOK A;  4E9F A;  2D0B A;  2JHN A;  3N5N X;  3OYI A;  2H4L X;  1FN7 A;  1R4X A;  2OOY A;  4TPS A;  4EA4 A;  4UOB A;  1PU8 A;  1AIS A;  4I8O A;  2JOI A;  2HZM A;  1LWW A;  1VKL A;  2IV8 A;  2NOH A;  3KTU A;  4DK9 A;  1YQR A;  1W80 A;  3OYM A;  5FRN A;  2NOI A;  2F7L A;  2V8Q A;  3N0U A;  1MPG A;  4PII A;  2V92 A;  1VTL E;  1K35 A;  1KYD A;  1QNC A;  1QTP A;  4E7J A;  2NOE A;  2W03 A;  2H5A X;  4BJU A;  1XQP A;  1KG2 A;  5KN9 A;  1U84 A;  3OYL A;  1RM1 A;  2NOL A;  4EAL A;  2FKF A;  3S3O A;  1WQA A;  3OYG A;  3OS2 A;  4D7Q A;  4WZS D;  2MZ8 A;  1P7M A;  3HS8 A;  1NKU A;  3FHF A;  3OSE A;  2EHB D;  4EA5 A;  1QTS A;  2YH5 A;  4B24 A;  5KL0 A;  1MP9 A;  4IKF A;  1C9B B;  3SNS A;  2NWV A;  2OFK A;  5F9C A;  2NVM A;  1JDY A;  1LWV A;  5IYB P;  1MUN A;  2Z8U A;  5DPK A;  1N3C A;  1KY7 A;  4C7P A;  3RSM A;  4ROC B;  3OST A;  1QN4 A;  1VRL A;  2R5X A;  3HS9 A; 
#chains in the Genus database with same CATH homology
 1PVS A;  5CHZ A;  4YPH A;  3FHG A;  3OH6 A;  3D4V A;  4EA4 A;  4UOB A;  3OH9 A;  3CWU A;  1PU8 A;  4AI4 A;  4AIA A;  1WEF A;  1LWW A;  3F10 A;  4E9H A;  2NOH A;  3KTU A;  4DK9 A;  1YQR A;  1PU6 A;  1HU0 A;  3CVS A;  2YG9 A;  5AN4 A;  1ORP A;  2NOI A;  1N39 A;  1DIZ A;  1KG7 A;  3N0U A;  1WEG A;  3OGD A;  1MPG A;  4PII A;  4EW0 A;  3FSP A;  1XQO A;  1KG5 A;  4EVV A;  1KG6 A;  2NOE A;  1RRQ A;  1XG7 A;  2OFI A;  1RRS A;  1XQP A;  1KG2 A;  4E9G A;  5KN9 A;  5KN8 A;  1PU7 A;  2NOB A;  3CVT A;  1ORN A;  2NOL A;  4B21 A;  2NOZ A;  3IH7 A;  3CWA A;  4B22 A;  4B23 A;  4YPR A;  4YOQ A;  3CWS A;  4OFA A;  3G0Q A;  4AI5 A;  1KQJ A;  1P7M A;  3IHO A;  2JHJ A;  2H56 A;  2NOF A;  1NKU A;  3FHF A;  2XHI A;  3I0X A;  4E9E A;  4EA5 A;  1WEI A;  1KG3 A;  3KNT A;  4OFH A;  4B24 A;  1NGN A;  1LWY A;  1MUD A;  3F0Z A;  4HSB A;  1P59 A;  2OFK A;  3S6I A;  1EBM A;  1KEA A;  1LWV A;  1N3A A;  2YG8 A;  1YQM A;  1MUN A;  3I0W A;  1KG4 A;  1LMZ A;  4UNF A;  2ABK A;  5DPK A;  1N3C A;  2JG6 A;  3CWT A;  1M3H A;  1M3Q A;  4E9F A;  2I5W A;  4OFE A;  1YQL A;  2JHN A;  4EW4 A;  3N5N X;  1KO9 A;  1MUY A;  4EJY A;  1VRL A;  1YQK A;  4EJZ A;  1FN7 A;  3CW7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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