1KG2A

Crystal structure of the core fragment of muty from e.coli at 1.2a resolution
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords A/G-specific adenine glycosylase
total genus 77
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg2A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg2A01
3D4VA 2NOHA 4EW4A 4B24A 1MUNA 4AI5A 3OGDA 4EA5A 3FHFA 2NOEA 2OFKA 3CWAA 2I5WA 1PU7A 2OFIA 3FSPA 4AIAA 4OFHA 1KG7A 4E9EA 4DK9A 1FN7A 4EJYA 2JHNA 1VRLA 1N3CA 3IH7A 1HU0A 1KG5A 1PU8A 1XG7A 5AN4A 4E9FA 1WEGA 3IHOA 3CWUA 4EVVA 1P59A 2XHIA 1N3AA 3CW7A 1KG6A 1YQLA 2NOBA 3CWSA 1MPGA 1WEIA 2H56A 1YQMA 4UNFA 2NOIA 3FHGA 3OH6A 5DPKA 1ORNA 4OFAA 1YQKA 1M3HA 3CVSA 1PVSA 2YG8A 1M3QA 1PU6A 1XQPA 2NOZA 1N39A 1LWYA 4OFEA 4B23A 1KEAA 3G0QA 4E9HA 1P7MA 4E9GA 4YOQA 4EA4A 2JG6A 1KG3A 3F0ZA 1NGNA 2JHJA 2NOLA 5KN8A 4EW0A 1DIZA 4HSBA 3F10A 1LMZA 3N0UA 4B21A 1MUDA 3S6IA 4B22A 1NKUA 1ORPA 1KG4A 3KTUA 4YPRA 1LWVA 4YPHA 1MUYA 1KO9A 5KN9A 1EBMA 1KG2A 3I0WA 3N5NX 2ABKA 1LWWA 1XQOA 3CWTA 3CVTA 1RRSA 4PIIA 5CHZA 3KNTA 4UOBA 3OH9A 1YQRA 2YG9A 4AI4A 1RRQA 3I0XA 4EJZA 2NOFA 1WEFA 1KQJA
chains in the Genus database with same CATH superfamily
3OS0A 3VW4A 3D4VA 2NOHA 3OY9A 3OYLA 4EW4A 4B24A 1MUNA 4E7LA 4AI5A 4NZGA 3OGDA 3R2XC 4ZTJA 4EA5A 3FHFA 5FROA 3OYAA 2NOEA 2OFKA 3CWAA 2I5WA 1PU7A 3OYFA 3FSPA 2OFIA 4AIAA 4IKFA 4OFHA 3OYGA 3OYNA 3OS1A 4E7KA 1KG7A 2W03A 4E7JA 4E9EA 4DK9A 1FN7A 4EJYA 1U84A 3LCNA 2JHNA 1VRLA 1N3CA 3IH7A 4E7IA 1HU0A 1KG5A 1PU8A 1XG7A 5AN4A 3S3NA 4E9FA 1WEGA 3IHOA 3CWUA 4EVVA 3OYEA 2XHIA 1P59A 3L2WA 1N3AA 3CW7A 1KG6A 1YQLA 3OYIA 2NOBA 3S3OA 4ZTFA 3CWSA 1MPGA 2W04A 1WEIA 2H56A 1YQMA 4BDZA 4UNFA 2NOIA 3FHGA 3OH6A 5DPKA 1ORNA 4BE2A 4OFAA 1YQKA 1M3HA 3CVSA 1PVSA 2YG8A 1M3QA 1PU6A 1XQPA 2NOZA 1N39A 1LWYA 4BE1A 4OFEA 4B23A 1KEAA 3G0QA 4E9HA 1P7MA 4E9GA 4YOQA 3OYHA 4EA4A 3OYMA 3OYKA 2JPSA 3L2RA 2JG6A 1KG3A 4E7HA 3F0ZA 1NGNA 2JHJA 2NOLA 5KN8A 4EW0A 1DIZA 4BACA 4HSBA 3F10A 1LMZA 3N0UA 4BDYA 4B21A 1MUDA 3S6IA 3L2QA 4B22A 3L2UA 1NKUA 1ORPA 1KG4A 3OYBA 3L2VA 3KTUA 3OYDA 4YPRA 3NNQA 1LWVA 5FRNA 2V75A 3OYJA 4YPHA 3S3MA 1MUYA 1KO9A 5KN9A 3OYCA 1EBMA 1KG2A 3I0WA 3N5NX 2ABKA 1LWWA 1XQOA 3CWTA 4BE0A 3CVTA 1RRSA 4PIIA 5CHZA 5FRMA 3KNTA 4UOBA 3OH9A 1YQRA 2YG9A 4AI4A 3OS2A 3I0XA 1RRQA 4EJZA 2NOFA 1WEFA 1KQJA
chains in the Genus database with same CATH topology
3D4VA 2NOHA 4EW4A 4B24A 1MUNA 4AI5A 3OGDA 4EA5A 3FHFA 2NOEA 2OFKA 3CWAA 2I5WA 1PU7A 2OFIA 3FSPA 4AIAA 4OFHA 1KG7A 4E9EA 4DK9A 1FN7A 4EJYA 2JHNA 1VRLA 1N3CA 3IH7A 1HU0A 1KG5A 1PU8A 1XG7A 5AN4A 4E9FA 1WEGA 3IHOA 3CWUA 4EVVA 1P59A 2XHIA 1N3AA 3CW7A 1KG6A 1YQLA 2NOBA 3CWSA 1MPGA 1WEIA 2H56A 1YQMA 4UNFA 2NOIA 3FHGA 3OH6A 5DPKA 1ORNA 4OFAA 1YQKA 1M3HA 3CVSA 1PVSA 2YG8A 1M3QA 1PU6A 1XQPA 2NOZA 1N39A 1LWYA 4OFEA 4B23A 1KEAA 3G0QA 4E9HA 1P7MA 4E9GA 4YOQA 4EA4A 2JG6A 1KG3A 3F0ZA 1NGNA 2JHJA 2NOLA 5KN8A 4EW0A 1DIZA 4HSBA 3F10A 1LMZA 3N0UA 4B21A 1MUDA 3S6IA 4B22A 1NKUA 1ORPA 1KG4A 3KTUA 4YPRA 1LWVA 4YPHA 1MUYA 1KO9A 5KN9A 1EBMA 1KG2A 3I0WA 3N5NX 2ABKA 1LWWA 1XQOA 3CWTA 3CVTA 1RRSA 4PIIA 5CHZA 3KNTA 4UOBA 3OH9A 1YQRA 2YG9A 4AI4A 1RRQA 3I0XA 4EJZA 2NOFA 1WEFA 1KQJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D4V A;  2NOH A;  4EW4 A;  4B24 A;  1MUN A;  4AI5 A;  3OGD A;  4EA5 A;  3FHF A;  2NOE A;  2OFK A;  3CWA A;  2I5W A;  1PU7 A;  2OFI A;  3FSP A;  4AIA A;  4OFH A;  1KG7 A;  4E9E A;  4DK9 A;  1FN7 A;  4EJY A;  2JHN A;  1VRL A;  1N3C A;  3IH7 A;  1HU0 A;  1KG5 A;  1PU8 A;  1XG7 A;  5AN4 A;  4E9F A;  1WEG A;  3IHO A;  3CWU A;  4EVV A;  1P59 A;  2XHI A;  1N3A A;  3CW7 A;  1KG6 A;  1YQL A;  2NOB A;  3CWS A;  1MPG A;  1WEI A;  2H56 A;  1YQM A;  4UNF A;  2NOI A;  3FHG A;  3OH6 A;  5DPK A;  1ORN A;  4OFA A;  1YQK A;  1M3H A;  3CVS A;  1PVS A;  2YG8 A;  1M3Q A;  1PU6 A;  1XQP A;  2NOZ A;  1N39 A;  1LWY A;  4OFE A;  4B23 A;  1KEA A;  3G0Q A;  4E9H A;  1P7M A;  4E9G A;  4YOQ A;  4EA4 A;  2JG6 A;  1KG3 A;  3F0Z A;  1NGN A;  2JHJ A;  2NOL A;  5KN8 A;  4EW0 A;  1DIZ A;  4HSB A;  3F10 A;  1LMZ A;  3N0U A;  4B21 A;  1MUD A;  3S6I A;  4B22 A;  1NKU A;  1ORP A;  1KG4 A;  3KTU A;  4YPR A;  1LWV A;  4YPH A;  1MUY A;  1KO9 A;  5KN9 A;  1EBM A;  1KG2 A;  3I0W A;  3N5N X;  2ABK A;  1LWW A;  1XQO A;  3CWT A;  3CVT A;  1RRS A;  4PII A;  5CHZ A;  3KNT A;  4UOB A;  3OH9 A;  1YQR A;  2YG9 A;  4AI4 A;  1RRQ A;  3I0X A;  4EJZ A;  2NOF A;  1WEF A;  1KQJ A; 
#chains in the Genus database with same CATH topology
 3OS0 A;  3VW4 A;  3D4V A;  2NOH A;  3OY9 A;  3OYL A;  4EW4 A;  4B24 A;  1MUN A;  4E7L A;  4AI5 A;  4NZG A;  3OGD A;  3R2X C;  4ZTJ A;  4EA5 A;  3FHF A;  5FRO A;  3OYA A;  2NOE A;  2OFK A;  3CWA A;  2I5W A;  1PU7 A;  3OYF A;  3FSP A;  2OFI A;  4AIA A;  4IKF A;  4OFH A;  3OYG A;  3OYN A;  3OS1 A;  4E7K A;  1KG7 A;  2W03 A;  4E7J A;  4E9E A;  4DK9 A;  1FN7 A;  4EJY A;  1U84 A;  3LCN A;  2JHN A;  1VRL A;  1N3C A;  3IH7 A;  4E7I A;  1HU0 A;  1KG5 A;  1PU8 A;  1XG7 A;  5AN4 A;  3S3N A;  4E9F A;  1WEG A;  3IHO A;  3CWU A;  4EVV A;  3OYE A;  2XHI A;  1P59 A;  3L2W A;  1N3A A;  3CW7 A;  1KG6 A;  1YQL A;  3OYI A;  2NOB A;  3S3O A;  4ZTF A;  3CWS A;  1MPG A;  2W04 A;  1WEI A;  2H56 A;  1YQM A;  4BDZ A;  4UNF A;  2NOI A;  3FHG A;  3OH6 A;  5DPK A;  1ORN A;  4BE2 A;  4OFA A;  1YQK A;  1M3H A;  3CVS A;  1PVS A;  2YG8 A;  1M3Q A;  1PU6 A;  1XQP A;  2NOZ A;  1N39 A;  1LWY A;  4BE1 A;  4OFE A;  4B23 A;  1KEA A;  3G0Q A;  4E9H A;  1P7M A;  4E9G A;  4YOQ A;  3OYH A;  4EA4 A;  3OYM A;  3OYK A;  2JPS A;  3L2R A;  2JG6 A;  1KG3 A;  4E7H A;  3F0Z A;  1NGN A;  2JHJ A;  2NOL A;  5KN8 A;  4EW0 A;  1DIZ A;  4BAC A;  4HSB A;  3F10 A;  1LMZ A;  3N0U A;  4BDY A;  4B21 A;  1MUD A;  3S6I A;  3L2Q A;  4B22 A;  3L2U A;  1NKU A;  1ORP A;  1KG4 A;  3OYB A;  3L2V A;  3KTU A;  3OYD A;  4YPR A;  3NNQ A;  1LWV A;  5FRN A;  2V75 A;  3OYJ A;  4YPH A;  3S3M A;  1MUY A;  1KO9 A;  5KN9 A;  3OYC A;  1EBM A;  1KG2 A;  3I0W A;  3N5N X;  2ABK A;  1LWW A;  1XQO A;  3CWT A;  4BE0 A;  3CVT A;  1RRS A;  4PII A;  5CHZ A;  5FRM A;  3KNT A;  4UOB A;  3OH9 A;  1YQR A;  2YG9 A;  4AI4 A;  3OS2 A;  3I0X A;  1RRQ A;  4EJZ A;  2NOF A;  1WEF A;  1KQJ A; 
#chains in the Genus database with same CATH homology
 3D4V A;  2NOH A;  4EW4 A;  4B24 A;  1MUN A;  4AI5 A;  3OGD A;  4EA5 A;  3FHF A;  2NOE A;  2OFK A;  3CWA A;  2I5W A;  1PU7 A;  2OFI A;  3FSP A;  4AIA A;  4OFH A;  1KG7 A;  4E9E A;  4DK9 A;  1FN7 A;  4EJY A;  2JHN A;  1VRL A;  1N3C A;  3IH7 A;  1HU0 A;  1KG5 A;  1PU8 A;  1XG7 A;  5AN4 A;  4E9F A;  1WEG A;  3IHO A;  3CWU A;  4EVV A;  1P59 A;  2XHI A;  1N3A A;  3CW7 A;  1KG6 A;  1YQL A;  2NOB A;  3CWS A;  1MPG A;  1WEI A;  2H56 A;  1YQM A;  4UNF A;  2NOI A;  3FHG A;  3OH6 A;  5DPK A;  1ORN A;  4OFA A;  1YQK A;  1M3H A;  3CVS A;  1PVS A;  2YG8 A;  1M3Q A;  1PU6 A;  1XQP A;  2NOZ A;  1N39 A;  1LWY A;  4OFE A;  4B23 A;  1KEA A;  3G0Q A;  4E9H A;  1P7M A;  4E9G A;  4YOQ A;  4EA4 A;  2JG6 A;  1KG3 A;  3F0Z A;  1NGN A;  2JHJ A;  2NOL A;  5KN8 A;  4EW0 A;  1DIZ A;  4HSB A;  3F10 A;  1LMZ A;  3N0U A;  4B21 A;  1MUD A;  3S6I A;  4B22 A;  1NKU A;  1ORP A;  1KG4 A;  3KTU A;  4YPR A;  1LWV A;  4YPH A;  1MUY A;  1KO9 A;  5KN9 A;  1EBM A;  1KG2 A;  3I0W A;  3N5N X;  2ABK A;  1LWW A;  1XQO A;  3CWT A;  3CVT A;  1RRS A;  4PII A;  5CHZ A;  3KNT A;  4UOB A;  3OH9 A;  1YQR A;  2YG9 A;  4AI4 A;  1RRQ A;  3I0X A;  4EJZ A;  2NOF A;  1WEF A;  1KQJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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