1KG2A

Crystal structure of the core fragment of muty from e.coli at 1.2a resolution
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Escherichia coli
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
molecule keywords A/G-specific adenine glycosylase
total genus 77
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg2A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg2A01
4PIIA 1YQRA 2OFIA 4E9EA 3IHOA 1KG3A 2NOZA 1YQMA 4DK9A 4EVVA 2YG8A 1N39A 4AI5A 3F10A 2JHJA 1HU0A 1RRQA 3KTUA 3CW7A 1XQPA 1FN7A 1NKUA 4EA5A 1KQJA 5KN9A 5CHZA 1P7MA 2NOBA 1LMZA 3OH6A 4EW4A 3FHGA 5AN4A 2OFKA 4HSBA 4YOQA 1PU7A 1NGNA 1N3AA 3OGDA 3S6IA 4E9FA 3G0QA 3CWUA 1MUYA 4OFEA 5DPKA 2NOLA 1MPGA 1VRLA 3I0WA 1KG4A 1KG6A 2YG9A 1KEAA 4B21A 1M3HA 4OFHA 4E9GA 3CWSA 2JHNA 4UNFA 1EBMA 3FSPA 4EJZA 1DIZA 2NOEA 3N0UA 1WEFA 3OH9A 1N3CA 1KG5A 4EW0A 1KG2A 1MUNA 4B24A 3IH7A 2I5WA 1PU8A 4OFAA 3D4VA 3FHFA 4E9HA 2NOHA 1KO9A 2JG6A 4AIAA 1YQLA 3CWTA 3KNTA 4B22A 1ORPA 2XHIA 1P59A 1LWYA 2H56A 4B23A 4AI4A 5KN8A 3CVSA 2NOFA 1KG7A 2ABKA 1M3QA 1YQKA 1MUDA 1XQOA 1WEGA 1XG7A 3CWAA 4YPRA 4YPHA 4EJYA 1LWWA 1PVSA 3F0ZA 1ORNA 3I0XA 4UOBA 3CVTA 3N5NX 4EA4A 1RRSA 1LWVA 2NOIA 1PU6A 1WEIA
chains in the Genus database with same CATH superfamily
4PIIA 1YQRA 5FRNA 2OFIA 4BDYA 3OYJA 4E9EA 4E7JA 3L2UA 3IHOA 1KG3A 2NOZA 1YQMA 3OYBA 3OS0A 4DK9A 3OYHA 4EVVA 4ZTFA 3R2XC 2YG8A 1N39A 3OYGA 4AI5A 3F10A 2JHJA 2V75A 1RRQA 1HU0A 3KTUA 3CW7A 1XQPA 1FN7A 1NKUA 4EA5A 1KQJA 2JPSA 4BE1A 3OYNA 4E7HA 5KN9A 5CHZA 1P7MA 2NOBA 1LMZA 3OS1A 3OH6A 4EW4A 3FHGA 3OYKA 3OYFA 5AN4A 2OFKA 4HSBA 4YOQA 1PU7A 1NGNA 4E7LA 1N3AA 3OGDA 3S6IA 4E9FA 2W04A 3G0QA 3CWUA 1MUYA 4OFEA 5DPKA 2NOLA 1MPGA 4BE0A 4BACA 3OYMA 3OS2A 3S3NA 1VRLA 3I0WA 1KG4A 1KG6A 3OY9A 2YG9A 1KEAA 4B21A 5FRMA 4BDZA 1M3HA 3L2VA 4OFHA 4E9GA 3L2QA 3CWSA 2JHNA 4UNFA 3OYEA 1EBMA 3S3OA 3FSPA 4EJZA 1DIZA 2NOEA 3OYIA 3N0UA 1WEFA 3OH9A 3VW4A 3S3MA 3L2WA 1N3CA 1KG5A 4ZTJA 4EW0A 1KG2A 1MUNA 4B24A 3IH7A 2I5WA 1PU8A 4OFAA 3D4VA 3FHFA 4E9HA 3L2RA 2NOHA 4BE2A 1KO9A 2JG6A 4IKFA 4AIAA 4NZGA 1YQLA 3CWTA 2W03A 3OYLA 3KNTA 3NNQA 4B22A 1ORPA 2XHIA 1P59A 1LWYA 2H56A 4B23A 4AI4A 5KN8A 3OYDA 5FROA 3CVSA 2NOFA 1KG7A 3OYCA 2ABKA 1M3QA 1YQKA 1MUDA 1XQOA 1WEGA 4E7IA 1XG7A 3CWAA 4YPRA 4YPHA 4EJYA 3LCNA 3OYAA 1U84A 1LWWA 1PVSA 3F0ZA 1ORNA 3I0XA 4UOBA 3CVTA 3N5NX 4EA4A 4E7KA 1RRSA 1LWVA 2NOIA 1PU6A 1WEIA
chains in the Genus database with same CATH topology
4PIIA 1YQRA 2OFIA 4E9EA 3IHOA 1KG3A 2NOZA 1YQMA 4DK9A 4EVVA 2YG8A 1N39A 4AI5A 3F10A 2JHJA 1HU0A 1RRQA 3KTUA 3CW7A 1XQPA 1FN7A 1NKUA 4EA5A 1KQJA 5KN9A 5CHZA 1P7MA 2NOBA 1LMZA 3OH6A 4EW4A 3FHGA 5AN4A 2OFKA 4HSBA 4YOQA 1PU7A 1NGNA 1N3AA 3OGDA 3S6IA 4E9FA 3G0QA 3CWUA 1MUYA 4OFEA 5DPKA 2NOLA 1MPGA 1VRLA 3I0WA 1KG4A 1KG6A 2YG9A 1KEAA 4B21A 1M3HA 4OFHA 4E9GA 3CWSA 2JHNA 4UNFA 1EBMA 3FSPA 4EJZA 1DIZA 2NOEA 3N0UA 1WEFA 3OH9A 1N3CA 1KG5A 4EW0A 1KG2A 1MUNA 4B24A 3IH7A 2I5WA 1PU8A 4OFAA 3D4VA 3FHFA 4E9HA 2NOHA 1KO9A 2JG6A 4AIAA 1YQLA 3CWTA 3KNTA 4B22A 1ORPA 2XHIA 1P59A 1LWYA 2H56A 4B23A 4AI4A 5KN8A 3CVSA 2NOFA 1KG7A 2ABKA 1M3QA 1YQKA 1MUDA 1XQOA 1WEGA 1XG7A 3CWAA 4YPRA 4YPHA 4EJYA 1LWWA 1PVSA 3F0ZA 1ORNA 3I0XA 4UOBA 3CVTA 3N5NX 4EA4A 1RRSA 1LWVA 2NOIA 1PU6A 1WEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PII A;  1YQR A;  2OFI A;  4E9E A;  3IHO A;  1KG3 A;  2NOZ A;  1YQM A;  4DK9 A;  4EVV A;  2YG8 A;  1N39 A;  4AI5 A;  3F10 A;  2JHJ A;  1HU0 A;  1RRQ A;  3KTU A;  3CW7 A;  1XQP A;  1FN7 A;  1NKU A;  4EA5 A;  1KQJ A;  5KN9 A;  5CHZ A;  1P7M A;  2NOB A;  1LMZ A;  3OH6 A;  4EW4 A;  3FHG A;  5AN4 A;  2OFK A;  4HSB A;  4YOQ A;  1PU7 A;  1NGN A;  1N3A A;  3OGD A;  3S6I A;  4E9F A;  3G0Q A;  3CWU A;  1MUY A;  4OFE A;  5DPK A;  2NOL A;  1MPG A;  1VRL A;  3I0W A;  1KG4 A;  1KG6 A;  2YG9 A;  1KEA A;  4B21 A;  1M3H A;  4OFH A;  4E9G A;  3CWS A;  2JHN A;  4UNF A;  1EBM A;  3FSP A;  4EJZ A;  1DIZ A;  2NOE A;  3N0U A;  1WEF A;  3OH9 A;  1N3C A;  1KG5 A;  4EW0 A;  1KG2 A;  1MUN A;  4B24 A;  3IH7 A;  2I5W A;  1PU8 A;  4OFA A;  3D4V A;  3FHF A;  4E9H A;  2NOH A;  1KO9 A;  2JG6 A;  4AIA A;  1YQL A;  3CWT A;  3KNT A;  4B22 A;  1ORP A;  2XHI A;  1P59 A;  1LWY A;  2H56 A;  4B23 A;  4AI4 A;  5KN8 A;  3CVS A;  2NOF A;  1KG7 A;  2ABK A;  1M3Q A;  1YQK A;  1MUD A;  1XQO A;  1WEG A;  1XG7 A;  3CWA A;  4YPR A;  4YPH A;  4EJY A;  1LWW A;  1PVS A;  3F0Z A;  1ORN A;  3I0X A;  4UOB A;  3CVT A;  3N5N X;  4EA4 A;  1RRS A;  1LWV A;  2NOI A;  1PU6 A;  1WEI A; 
#chains in the Genus database with same CATH topology
 4PII A;  1YQR A;  5FRN A;  2OFI A;  4BDY A;  3OYJ A;  4E9E A;  4E7J A;  3L2U A;  3IHO A;  1KG3 A;  2NOZ A;  1YQM A;  3OYB A;  3OS0 A;  4DK9 A;  3OYH A;  4EVV A;  4ZTF A;  3R2X C;  2YG8 A;  1N39 A;  3OYG A;  4AI5 A;  3F10 A;  2JHJ A;  2V75 A;  1RRQ A;  1HU0 A;  3KTU A;  3CW7 A;  1XQP A;  1FN7 A;  1NKU A;  4EA5 A;  1KQJ A;  2JPS A;  4BE1 A;  3OYN A;  4E7H A;  5KN9 A;  5CHZ A;  1P7M A;  2NOB A;  1LMZ A;  3OS1 A;  3OH6 A;  4EW4 A;  3FHG A;  3OYK A;  3OYF A;  5AN4 A;  2OFK A;  4HSB A;  4YOQ A;  1PU7 A;  1NGN A;  4E7L A;  1N3A A;  3OGD A;  3S6I A;  4E9F A;  2W04 A;  3G0Q A;  3CWU A;  1MUY A;  4OFE A;  5DPK A;  2NOL A;  1MPG A;  4BE0 A;  4BAC A;  3OYM A;  3OS2 A;  3S3N A;  1VRL A;  3I0W A;  1KG4 A;  1KG6 A;  3OY9 A;  2YG9 A;  1KEA A;  4B21 A;  5FRM A;  4BDZ A;  1M3H A;  3L2V A;  4OFH A;  4E9G A;  3L2Q A;  3CWS A;  2JHN A;  4UNF A;  3OYE A;  1EBM A;  3S3O A;  3FSP A;  4EJZ A;  1DIZ A;  2NOE A;  3OYI A;  3N0U A;  1WEF A;  3OH9 A;  3VW4 A;  3S3M A;  3L2W A;  1N3C A;  1KG5 A;  4ZTJ A;  4EW0 A;  1KG2 A;  1MUN A;  4B24 A;  3IH7 A;  2I5W A;  1PU8 A;  4OFA A;  3D4V A;  3FHF A;  4E9H A;  3L2R A;  2NOH A;  4BE2 A;  1KO9 A;  2JG6 A;  4IKF A;  4AIA A;  4NZG A;  1YQL A;  3CWT A;  2W03 A;  3OYL A;  3KNT A;  3NNQ A;  4B22 A;  1ORP A;  2XHI A;  1P59 A;  1LWY A;  2H56 A;  4B23 A;  4AI4 A;  5KN8 A;  3OYD A;  5FRO A;  3CVS A;  2NOF A;  1KG7 A;  3OYC A;  2ABK A;  1M3Q A;  1YQK A;  1MUD A;  1XQO A;  1WEG A;  4E7I A;  1XG7 A;  3CWA A;  4YPR A;  4YPH A;  4EJY A;  3LCN A;  3OYA A;  1U84 A;  1LWW A;  1PVS A;  3F0Z A;  1ORN A;  3I0X A;  4UOB A;  3CVT A;  3N5N X;  4EA4 A;  4E7K A;  1RRS A;  1LWV A;  2NOI A;  1PU6 A;  1WEI A; 
#chains in the Genus database with same CATH homology
 4PII A;  1YQR A;  2OFI A;  4E9E A;  3IHO A;  1KG3 A;  2NOZ A;  1YQM A;  4DK9 A;  4EVV A;  2YG8 A;  1N39 A;  4AI5 A;  3F10 A;  2JHJ A;  1HU0 A;  1RRQ A;  3KTU A;  3CW7 A;  1XQP A;  1FN7 A;  1NKU A;  4EA5 A;  1KQJ A;  5KN9 A;  5CHZ A;  1P7M A;  2NOB A;  1LMZ A;  3OH6 A;  4EW4 A;  3FHG A;  5AN4 A;  2OFK A;  4HSB A;  4YOQ A;  1PU7 A;  1NGN A;  1N3A A;  3OGD A;  3S6I A;  4E9F A;  3G0Q A;  3CWU A;  1MUY A;  4OFE A;  5DPK A;  2NOL A;  1MPG A;  1VRL A;  3I0W A;  1KG4 A;  1KG6 A;  2YG9 A;  1KEA A;  4B21 A;  1M3H A;  4OFH A;  4E9G A;  3CWS A;  2JHN A;  4UNF A;  1EBM A;  3FSP A;  4EJZ A;  1DIZ A;  2NOE A;  3N0U A;  1WEF A;  3OH9 A;  1N3C A;  1KG5 A;  4EW0 A;  1KG2 A;  1MUN A;  4B24 A;  3IH7 A;  2I5W A;  1PU8 A;  4OFA A;  3D4V A;  3FHF A;  4E9H A;  2NOH A;  1KO9 A;  2JG6 A;  4AIA A;  1YQL A;  3CWT A;  3KNT A;  4B22 A;  1ORP A;  2XHI A;  1P59 A;  1LWY A;  2H56 A;  4B23 A;  4AI4 A;  5KN8 A;  3CVS A;  2NOF A;  1KG7 A;  2ABK A;  1M3Q A;  1YQK A;  1MUD A;  1XQO A;  1WEG A;  1XG7 A;  3CWA A;  4YPR A;  4YPH A;  4EJY A;  1LWW A;  1PVS A;  3F0Z A;  1ORN A;  3I0X A;  4UOB A;  3CVT A;  3N5N X;  4EA4 A;  1RRS A;  1LWV A;  2NOI A;  1PU6 A;  1WEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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