1KG5A

Crystal structure of the k142q mutant of e.coli muty (core fragment)
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVQRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords A/G-specific adenine glycosylase
total genus 77
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg5A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg5A01
1LWYA 2YG9A 1KG4A 4YOQA 4E9HA 4YPHA 4AI4A 4HSBA 4DK9A 2JHNA 3CWAA 1MUDA 3OH9A 5CHZA 3CWTA 1NKUA 4EW4A 4YPRA 4AIAA 4B21A 1KG7A 4EVVA 2NOIA 2H56A 4E9EA 2I5WA 1ORPA 3CVSA 2NOHA 3G0QA 3I0WA 3KTUA 1VRLA 4EJZA 1YQMA 1PU8A 1KQJA 3CW7A 4B24A 4EJYA 1KO9A 1EBMA 2ABKA 1N3AA 1XG7A 4UOBA 2NOBA 5AN4A 3S6IA 2NOZA 2OFKA 4EA4A 1MUYA 1YQRA 4OFAA 4EW0A 1KG5A 2NOEA 1LMZA 1XQPA 2OFIA 1HU0A 1P59A 4UNFA 2YG8A 5KN9A 3FHFA 1RRSA 2NOLA 3FSPA 1MPGA 4PIIA 4E9FA 1PU7A 3N0UA 1M3QA 2JHJA 4AI5A 1RRQA 1PU6A 4B23A 1M3HA 1YQKA 3CWSA 1ORNA 1WEGA 1DIZA 1KG3A 3OGDA 2JG6A 5DPKA 1YQLA 3IH7A 1WEFA 1N3CA 1KG2A 3I0XA 3IHOA 1XQOA 1WEIA 1FN7A 1P7MA 1N39A 4OFHA 3FHGA 4EA5A 4E9GA 2XHIA 3CWUA 1KEAA 3KNTA 4OFEA 1MUNA 3CVTA 3F10A 1LWVA 3D4VA 4B22A 1KG6A 1NGNA 3F0ZA 3N5NX 3OH6A 5KN8A 1LWWA 1PVSA 2NOFA
chains in the Genus database with same CATH superfamily
1LWYA 2YG9A 1KG4A 4YOQA 4E9HA 4YPHA 4AI4A 4HSBA 4DK9A 2JHNA 3CWAA 1MUDA 3OH9A 5CHZA 3CWTA 1NKUA 3L2WA 4EW4A 4YPRA 4AIAA 4B21A 1KG7A 3OYIA 4EVVA 2NOIA 2H56A 4IKFA 4E9EA 2I5WA 1U84A 1ORPA 3CVSA 2NOHA 3G0QA 3I0WA 4E7JA 3KTUA 3OYJA 1VRLA 4ZTFA 4EJZA 1YQMA 4E7IA 1PU8A 1KQJA 3CW7A 3OYDA 4B24A 3VW4A 4EJYA 4E7LA 1KO9A 3OY9A 3OYKA 1EBMA 2ABKA 1N3AA 1XG7A 4UOBA 2NOBA 5AN4A 3S6IA 2NOZA 5FRNA 2OFKA 3OYGA 2W04A 4EA4A 3L2RA 1MUYA 1YQRA 2JPSA 4OFAA 4EW0A 1KG5A 2NOEA 1LMZA 5FRMA 5FROA 1XQPA 4BE0A 2OFIA 1HU0A 4BDYA 1P59A 4UNFA 2YG8A 5KN9A 3OYAA 3FHFA 3OYLA 2V75A 1RRSA 4BACA 2NOLA 3FSPA 1MPGA 4NZGA 4PIIA 4E9FA 1PU7A 4BE2A 3N0UA 1M3QA 2JHJA 4AI5A 4BE1A 4BDZA 3OYCA 1RRQA 1PU6A 4B23A 1M3HA 1YQKA 3OS0A 1ORNA 1WEGA 3CWSA 3LCNA 3OYEA 1DIZA 3R2XC 1KG3A 3S3OA 3OYHA 3OGDA 2JG6A 3S3MA 5DPKA 1YQLA 3IH7A 1WEFA 1N3CA 4E7KA 1KG2A 3OS1A 3I0XA 3IHOA 3L2QA 1XQOA 1WEIA 1FN7A 1P7MA 1N39A 4OFHA 3FHGA 3OYBA 4EA5A 4E9GA 2XHIA 3OYNA 3CWUA 1KEAA 3L2VA 3NNQA 3OYFA 3KNTA 4OFEA 1MUNA 2W03A 3CVTA 3F10A 4E7HA 3D4VA 3OYMA 1LWVA 3OS2A 3L2UA 3S3NA 1KG6A 1NGNA 3N5NX 3F0ZA 3OH6A 4B22A 5KN8A 1LWWA 4ZTJA 1PVSA 2NOFA
chains in the Genus database with same CATH topology
1LWYA 2YG9A 1KG4A 4YOQA 4E9HA 4YPHA 4AI4A 4HSBA 4DK9A 2JHNA 3CWAA 1MUDA 3OH9A 5CHZA 3CWTA 1NKUA 4EW4A 4YPRA 4AIAA 4B21A 1KG7A 4EVVA 2NOIA 2H56A 4E9EA 2I5WA 1ORPA 3CVSA 2NOHA 3G0QA 3I0WA 3KTUA 1VRLA 4EJZA 1YQMA 1PU8A 1KQJA 3CW7A 4B24A 4EJYA 1KO9A 1EBMA 2ABKA 1N3AA 1XG7A 4UOBA 2NOBA 5AN4A 3S6IA 2NOZA 2OFKA 4EA4A 1MUYA 1YQRA 4OFAA 4EW0A 1KG5A 2NOEA 1LMZA 1XQPA 2OFIA 1HU0A 1P59A 4UNFA 2YG8A 5KN9A 3FHFA 1RRSA 2NOLA 3FSPA 1MPGA 4PIIA 4E9FA 1PU7A 3N0UA 1M3QA 2JHJA 4AI5A 1RRQA 1PU6A 4B23A 1M3HA 1YQKA 3CWSA 1ORNA 1WEGA 1DIZA 1KG3A 3OGDA 2JG6A 5DPKA 1YQLA 3IH7A 1WEFA 1N3CA 1KG2A 3I0XA 3IHOA 1XQOA 1WEIA 1FN7A 1P7MA 1N39A 4OFHA 3FHGA 4EA5A 4E9GA 2XHIA 3CWUA 1KEAA 3KNTA 4OFEA 1MUNA 3CVTA 3F10A 1LWVA 3D4VA 4B22A 1KG6A 1NGNA 3F0ZA 3N5NX 3OH6A 5KN8A 1LWWA 1PVSA 2NOFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LWY A;  2YG9 A;  1KG4 A;  4YOQ A;  4E9H A;  4YPH A;  4AI4 A;  4HSB A;  4DK9 A;  2JHN A;  3CWA A;  1MUD A;  3OH9 A;  5CHZ A;  3CWT A;  1NKU A;  4EW4 A;  4YPR A;  4AIA A;  4B21 A;  1KG7 A;  4EVV A;  2NOI A;  2H56 A;  4E9E A;  2I5W A;  1ORP A;  3CVS A;  2NOH A;  3G0Q A;  3I0W A;  3KTU A;  1VRL A;  4EJZ A;  1YQM A;  1PU8 A;  1KQJ A;  3CW7 A;  4B24 A;  4EJY A;  1KO9 A;  1EBM A;  2ABK A;  1N3A A;  1XG7 A;  4UOB A;  2NOB A;  5AN4 A;  3S6I A;  2NOZ A;  2OFK A;  4EA4 A;  1MUY A;  1YQR A;  4OFA A;  4EW0 A;  1KG5 A;  2NOE A;  1LMZ A;  1XQP A;  2OFI A;  1HU0 A;  1P59 A;  4UNF A;  2YG8 A;  5KN9 A;  3FHF A;  1RRS A;  2NOL A;  3FSP A;  1MPG A;  4PII A;  4E9F A;  1PU7 A;  3N0U A;  1M3Q A;  2JHJ A;  4AI5 A;  1RRQ A;  1PU6 A;  4B23 A;  1M3H A;  1YQK A;  3CWS A;  1ORN A;  1WEG A;  1DIZ A;  1KG3 A;  3OGD A;  2JG6 A;  5DPK A;  1YQL A;  3IH7 A;  1WEF A;  1N3C A;  1KG2 A;  3I0X A;  3IHO A;  1XQO A;  1WEI A;  1FN7 A;  1P7M A;  1N39 A;  4OFH A;  3FHG A;  4EA5 A;  4E9G A;  2XHI A;  3CWU A;  1KEA A;  3KNT A;  4OFE A;  1MUN A;  3CVT A;  3F10 A;  1LWV A;  3D4V A;  4B22 A;  1KG6 A;  1NGN A;  3F0Z A;  3N5N X;  3OH6 A;  5KN8 A;  1LWW A;  1PVS A;  2NOF A; 
#chains in the Genus database with same CATH topology
 1LWY A;  2YG9 A;  1KG4 A;  4YOQ A;  4E9H A;  4YPH A;  4AI4 A;  4HSB A;  4DK9 A;  2JHN A;  3CWA A;  1MUD A;  3OH9 A;  5CHZ A;  3CWT A;  1NKU A;  3L2W A;  4EW4 A;  4YPR A;  4AIA A;  4B21 A;  1KG7 A;  3OYI A;  4EVV A;  2NOI A;  2H56 A;  4IKF A;  4E9E A;  2I5W A;  1U84 A;  1ORP A;  3CVS A;  2NOH A;  3G0Q A;  3I0W A;  4E7J A;  3KTU A;  3OYJ A;  1VRL A;  4ZTF A;  4EJZ A;  1YQM A;  4E7I A;  1PU8 A;  1KQJ A;  3CW7 A;  3OYD A;  4B24 A;  3VW4 A;  4EJY A;  4E7L A;  1KO9 A;  3OY9 A;  3OYK A;  1EBM A;  2ABK A;  1N3A A;  1XG7 A;  4UOB A;  2NOB A;  5AN4 A;  3S6I A;  2NOZ A;  5FRN A;  2OFK A;  3OYG A;  2W04 A;  4EA4 A;  3L2R A;  1MUY A;  1YQR A;  2JPS A;  4OFA A;  4EW0 A;  1KG5 A;  2NOE A;  1LMZ A;  5FRM A;  5FRO A;  1XQP A;  4BE0 A;  2OFI A;  1HU0 A;  4BDY A;  1P59 A;  4UNF A;  2YG8 A;  5KN9 A;  3OYA A;  3FHF A;  3OYL A;  2V75 A;  1RRS A;  4BAC A;  2NOL A;  3FSP A;  1MPG A;  4NZG A;  4PII A;  4E9F A;  1PU7 A;  4BE2 A;  3N0U A;  1M3Q A;  2JHJ A;  4AI5 A;  4BE1 A;  4BDZ A;  3OYC A;  1RRQ A;  1PU6 A;  4B23 A;  1M3H A;  1YQK A;  3OS0 A;  1ORN A;  1WEG A;  3CWS A;  3LCN A;  3OYE A;  1DIZ A;  3R2X C;  1KG3 A;  3S3O A;  3OYH A;  3OGD A;  2JG6 A;  3S3M A;  5DPK A;  1YQL A;  3IH7 A;  1WEF A;  1N3C A;  4E7K A;  1KG2 A;  3OS1 A;  3I0X A;  3IHO A;  3L2Q A;  1XQO A;  1WEI A;  1FN7 A;  1P7M A;  1N39 A;  4OFH A;  3FHG A;  3OYB A;  4EA5 A;  4E9G A;  2XHI A;  3OYN A;  3CWU A;  1KEA A;  3L2V A;  3NNQ A;  3OYF A;  3KNT A;  4OFE A;  1MUN A;  2W03 A;  3CVT A;  3F10 A;  4E7H A;  3D4V A;  3OYM A;  1LWV A;  3OS2 A;  3L2U A;  3S3N A;  1KG6 A;  1NGN A;  3N5N X;  3F0Z A;  3OH6 A;  4B22 A;  5KN8 A;  1LWW A;  4ZTJ A;  1PVS A;  2NOF A; 
#chains in the Genus database with same CATH homology
 1LWY A;  2YG9 A;  1KG4 A;  4YOQ A;  4E9H A;  4YPH A;  4AI4 A;  4HSB A;  4DK9 A;  2JHN A;  3CWA A;  1MUD A;  3OH9 A;  5CHZ A;  3CWT A;  1NKU A;  4EW4 A;  4YPR A;  4AIA A;  4B21 A;  1KG7 A;  4EVV A;  2NOI A;  2H56 A;  4E9E A;  2I5W A;  1ORP A;  3CVS A;  2NOH A;  3G0Q A;  3I0W A;  3KTU A;  1VRL A;  4EJZ A;  1YQM A;  1PU8 A;  1KQJ A;  3CW7 A;  4B24 A;  4EJY A;  1KO9 A;  1EBM A;  2ABK A;  1N3A A;  1XG7 A;  4UOB A;  2NOB A;  5AN4 A;  3S6I A;  2NOZ A;  2OFK A;  4EA4 A;  1MUY A;  1YQR A;  4OFA A;  4EW0 A;  1KG5 A;  2NOE A;  1LMZ A;  1XQP A;  2OFI A;  1HU0 A;  1P59 A;  4UNF A;  2YG8 A;  5KN9 A;  3FHF A;  1RRS A;  2NOL A;  3FSP A;  1MPG A;  4PII A;  4E9F A;  1PU7 A;  3N0U A;  1M3Q A;  2JHJ A;  4AI5 A;  1RRQ A;  1PU6 A;  4B23 A;  1M3H A;  1YQK A;  3CWS A;  1ORN A;  1WEG A;  1DIZ A;  1KG3 A;  3OGD A;  2JG6 A;  5DPK A;  1YQL A;  3IH7 A;  1WEF A;  1N3C A;  1KG2 A;  3I0X A;  3IHO A;  1XQO A;  1WEI A;  1FN7 A;  1P7M A;  1N39 A;  4OFH A;  3FHG A;  4EA5 A;  4E9G A;  2XHI A;  3CWU A;  1KEA A;  3KNT A;  4OFE A;  1MUN A;  3CVT A;  3F10 A;  1LWV A;  3D4V A;  4B22 A;  1KG6 A;  1NGN A;  3F0Z A;  3N5N X;  3OH6 A;  5KN8 A;  1LWW A;  1PVS A;  2NOF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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