1KG5A

Crystal structure of the k142q mutant of e.coli muty (core fragment)
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVQRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Escherichia coli
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
molecule keywords A/G-specific adenine glycosylase
total genus 77
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg5A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg5A01
2NOFA 1EBMA 3S6IA 1ORPA 2H56A 2YG9A 2OFKA 3N0UA 3KTUA 1XQPA 3OH9A 3OGDA 3CWTA 2NOZA 1LMZA 1P59A 4B22A 1KG6A 1KO9A 3I0WA 1LWVA 1PU8A 4E9EA 4HSBA 1ORNA 1RRQA 4UNFA 1XQOA 1KG7A 3CWSA 1YQKA 4EW0A 1HU0A 3CWUA 4AI5A 3I0XA 5KN9A 5DPKA 1YQLA 4B24A 2NOLA 4OFEA 4EJZA 4EA4A 1KEAA 2JHJA 1FN7A 5AN4A 1KG3A 4EJYA 1LWYA 4B21A 4YOQA 1WEIA 1MUNA 2NOBA 3F10A 1M3HA 2NOHA 4AIAA 2OFIA 4EA5A 2ABKA 3IHOA 1N3AA 1KG4A 1KQJA 4YPHA 1NKUA 1XG7A 4DK9A 1DIZA 3CVSA 4OFAA 5CHZA 1WEGA 2NOIA 1KG5A 3D4VA 1PVSA 2JHNA 2I5WA 4PIIA 1MUDA 1WEFA 1N3CA 1RRSA 4B23A 3IH7A 2NOEA 1YQRA 3CW7A 1KG2A 1NGNA 3FHGA 3OH6A 1PU6A 4EW4A 3G0QA 2JG6A 1P7MA 5KN8A 3N5NX 4E9HA 1LWWA 3CWAA 4AI4A 4YPRA 4E9GA 2YG8A 1MPGA 1PU7A 4EVVA 1M3QA 1VRLA 4UOBA 4E9FA 3KNTA 1N39A 3F0ZA 3FSPA 3FHFA 4OFHA 1MUYA 3CVTA 2XHIA 1YQMA
chains in the Genus database with same CATH superfamily
2NOFA 1EBMA 3S6IA 1ORPA 2H56A 2YG9A 2OFKA 3N0UA 3KTUA 1XQPA 3OYDA 3OH9A 3OGDA 3L2VA 3CWTA 1U84A 2JPSA 1LMZA 2NOZA 1P59A 4IKFA 4B22A 1KG6A 1KO9A 3I0WA 3VW4A 3OYGA 1LWVA 3OYMA 3OS2A 1PU8A 4E9EA 4HSBA 3OS0A 3OYHA 1ORNA 5FRNA 1RRQA 4UNFA 1XQOA 1KG7A 4BDZA 3CWSA 1YQKA 4EW0A 1HU0A 3CWUA 4AI5A 3I0XA 5KN9A 5DPKA 3OYAA 1YQLA 4B24A 4BACA 3LCNA 2NOLA 5FROA 3OYBA 4OFEA 3L2UA 4EA4A 4EJZA 1KEAA 3OYNA 2JHJA 1FN7A 5AN4A 3OYEA 1KG3A 4EJYA 1LWYA 4B21A 4YOQA 1WEIA 1MUNA 2NOBA 3F10A 4BE1A 1M3HA 2NOHA 4E7IA 4AIAA 2OFIA 4EA5A 4ZTFA 2ABKA 3IHOA 1N3AA 1KG4A 3OYLA 1KQJA 4YPHA 1NKUA 1XG7A 4DK9A 1DIZA 3CVSA 4OFAA 5CHZA 1WEGA 2NOIA 1KG5A 3D4VA 1PVSA 2JHNA 2I5WA 4PIIA 1MUDA 1WEFA 3L2QA 1N3CA 1RRSA 4BDYA 4B23A 4E7KA 3IH7A 2NOEA 3OYKA 1YQRA 1KG2A 3CW7A 4BE0A 1NGNA 3FHGA 3OYJA 3OH6A 3OYIA 1PU6A 4EW4A 3S3OA 3G0QA 5FRMA 2JG6A 1P7MA 2W03A 4NZGA 4BE2A 5KN8A 3N5NX 4E9HA 1LWWA 3CWAA 4AI4A 3OYCA 3S3MA 4YPRA 3L2RA 3R2XC 4E7JA 4E9GA 2YG8A 4E7LA 3S3NA 3NNQA 1MPGA 2W04A 4ZTJA 1PU7A 4EVVA 1M3QA 1VRLA 4UOBA 4E9FA 2V75A 3OY9A 3OYFA 3KNTA 1N39A 3F0ZA 3FSPA 3FHFA 4OFHA 3L2WA 1MUYA 3OS1A 4E7HA 3CVTA 2XHIA 1YQMA
chains in the Genus database with same CATH topology
2NOFA 1EBMA 3S6IA 1ORPA 2H56A 2YG9A 2OFKA 3N0UA 3KTUA 1XQPA 3OH9A 3OGDA 3CWTA 2NOZA 1LMZA 1P59A 4B22A 1KG6A 1KO9A 3I0WA 1LWVA 1PU8A 4E9EA 4HSBA 1ORNA 1RRQA 4UNFA 1XQOA 1KG7A 3CWSA 1YQKA 4EW0A 1HU0A 3CWUA 4AI5A 3I0XA 5KN9A 5DPKA 1YQLA 4B24A 2NOLA 4OFEA 4EJZA 4EA4A 1KEAA 2JHJA 1FN7A 5AN4A 1KG3A 4EJYA 1LWYA 4B21A 4YOQA 1WEIA 1MUNA 2NOBA 3F10A 1M3HA 2NOHA 4AIAA 2OFIA 4EA5A 2ABKA 3IHOA 1N3AA 1KG4A 1KQJA 4YPHA 1NKUA 1XG7A 4DK9A 1DIZA 3CVSA 4OFAA 5CHZA 1WEGA 2NOIA 1KG5A 3D4VA 1PVSA 2JHNA 2I5WA 4PIIA 1MUDA 1WEFA 1N3CA 1RRSA 4B23A 3IH7A 2NOEA 1YQRA 3CW7A 1KG2A 1NGNA 3FHGA 3OH6A 1PU6A 4EW4A 3G0QA 2JG6A 1P7MA 5KN8A 3N5NX 4E9HA 1LWWA 3CWAA 4AI4A 4YPRA 4E9GA 2YG8A 1MPGA 1PU7A 4EVVA 1M3QA 1VRLA 4UOBA 4E9FA 3KNTA 1N39A 3F0ZA 3FSPA 3FHFA 4OFHA 1MUYA 3CVTA 2XHIA 1YQMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NOF A;  1EBM A;  3S6I A;  1ORP A;  2H56 A;  2YG9 A;  2OFK A;  3N0U A;  3KTU A;  1XQP A;  3OH9 A;  3OGD A;  3CWT A;  2NOZ A;  1LMZ A;  1P59 A;  4B22 A;  1KG6 A;  1KO9 A;  3I0W A;  1LWV A;  1PU8 A;  4E9E A;  4HSB A;  1ORN A;  1RRQ A;  4UNF A;  1XQO A;  1KG7 A;  3CWS A;  1YQK A;  4EW0 A;  1HU0 A;  3CWU A;  4AI5 A;  3I0X A;  5KN9 A;  5DPK A;  1YQL A;  4B24 A;  2NOL A;  4OFE A;  4EJZ A;  4EA4 A;  1KEA A;  2JHJ A;  1FN7 A;  5AN4 A;  1KG3 A;  4EJY A;  1LWY A;  4B21 A;  4YOQ A;  1WEI A;  1MUN A;  2NOB A;  3F10 A;  1M3H A;  2NOH A;  4AIA A;  2OFI A;  4EA5 A;  2ABK A;  3IHO A;  1N3A A;  1KG4 A;  1KQJ A;  4YPH A;  1NKU A;  1XG7 A;  4DK9 A;  1DIZ A;  3CVS A;  4OFA A;  5CHZ A;  1WEG A;  2NOI A;  1KG5 A;  3D4V A;  1PVS A;  2JHN A;  2I5W A;  4PII A;  1MUD A;  1WEF A;  1N3C A;  1RRS A;  4B23 A;  3IH7 A;  2NOE A;  1YQR A;  3CW7 A;  1KG2 A;  1NGN A;  3FHG A;  3OH6 A;  1PU6 A;  4EW4 A;  3G0Q A;  2JG6 A;  1P7M A;  5KN8 A;  3N5N X;  4E9H A;  1LWW A;  3CWA A;  4AI4 A;  4YPR A;  4E9G A;  2YG8 A;  1MPG A;  1PU7 A;  4EVV A;  1M3Q A;  1VRL A;  4UOB A;  4E9F A;  3KNT A;  1N39 A;  3F0Z A;  3FSP A;  3FHF A;  4OFH A;  1MUY A;  3CVT A;  2XHI A;  1YQM A; 
#chains in the Genus database with same CATH topology
 2NOF A;  1EBM A;  3S6I A;  1ORP A;  2H56 A;  2YG9 A;  2OFK A;  3N0U A;  3KTU A;  1XQP A;  3OYD A;  3OH9 A;  3OGD A;  3L2V A;  3CWT A;  1U84 A;  2JPS A;  1LMZ A;  2NOZ A;  1P59 A;  4IKF A;  4B22 A;  1KG6 A;  1KO9 A;  3I0W A;  3VW4 A;  3OYG A;  1LWV A;  3OYM A;  3OS2 A;  1PU8 A;  4E9E A;  4HSB A;  3OS0 A;  3OYH A;  1ORN A;  5FRN A;  1RRQ A;  4UNF A;  1XQO A;  1KG7 A;  4BDZ A;  3CWS A;  1YQK A;  4EW0 A;  1HU0 A;  3CWU A;  4AI5 A;  3I0X A;  5KN9 A;  5DPK A;  3OYA A;  1YQL A;  4B24 A;  4BAC A;  3LCN A;  2NOL A;  5FRO A;  3OYB A;  4OFE A;  3L2U A;  4EA4 A;  4EJZ A;  1KEA A;  3OYN A;  2JHJ A;  1FN7 A;  5AN4 A;  3OYE A;  1KG3 A;  4EJY A;  1LWY A;  4B21 A;  4YOQ A;  1WEI A;  1MUN A;  2NOB A;  3F10 A;  4BE1 A;  1M3H A;  2NOH A;  4E7I A;  4AIA A;  2OFI A;  4EA5 A;  4ZTF A;  2ABK A;  3IHO A;  1N3A A;  1KG4 A;  3OYL A;  1KQJ A;  4YPH A;  1NKU A;  1XG7 A;  4DK9 A;  1DIZ A;  3CVS A;  4OFA A;  5CHZ A;  1WEG A;  2NOI A;  1KG5 A;  3D4V A;  1PVS A;  2JHN A;  2I5W A;  4PII A;  1MUD A;  1WEF A;  3L2Q A;  1N3C A;  1RRS A;  4BDY A;  4B23 A;  4E7K A;  3IH7 A;  2NOE A;  3OYK A;  1YQR A;  1KG2 A;  3CW7 A;  4BE0 A;  1NGN A;  3FHG A;  3OYJ A;  3OH6 A;  3OYI A;  1PU6 A;  4EW4 A;  3S3O A;  3G0Q A;  5FRM A;  2JG6 A;  1P7M A;  2W03 A;  4NZG A;  4BE2 A;  5KN8 A;  3N5N X;  4E9H A;  1LWW A;  3CWA A;  4AI4 A;  3OYC A;  3S3M A;  4YPR A;  3L2R A;  3R2X C;  4E7J A;  4E9G A;  2YG8 A;  4E7L A;  3S3N A;  3NNQ A;  1MPG A;  2W04 A;  4ZTJ A;  1PU7 A;  4EVV A;  1M3Q A;  1VRL A;  4UOB A;  4E9F A;  2V75 A;  3OY9 A;  3OYF A;  3KNT A;  1N39 A;  3F0Z A;  3FSP A;  3FHF A;  4OFH A;  3L2W A;  1MUY A;  3OS1 A;  4E7H A;  3CVT A;  2XHI A;  1YQM A; 
#chains in the Genus database with same CATH homology
 2NOF A;  1EBM A;  3S6I A;  1ORP A;  2H56 A;  2YG9 A;  2OFK A;  3N0U A;  3KTU A;  1XQP A;  3OH9 A;  3OGD A;  3CWT A;  2NOZ A;  1LMZ A;  1P59 A;  4B22 A;  1KG6 A;  1KO9 A;  3I0W A;  1LWV A;  1PU8 A;  4E9E A;  4HSB A;  1ORN A;  1RRQ A;  4UNF A;  1XQO A;  1KG7 A;  3CWS A;  1YQK A;  4EW0 A;  1HU0 A;  3CWU A;  4AI5 A;  3I0X A;  5KN9 A;  5DPK A;  1YQL A;  4B24 A;  2NOL A;  4OFE A;  4EJZ A;  4EA4 A;  1KEA A;  2JHJ A;  1FN7 A;  5AN4 A;  1KG3 A;  4EJY A;  1LWY A;  4B21 A;  4YOQ A;  1WEI A;  1MUN A;  2NOB A;  3F10 A;  1M3H A;  2NOH A;  4AIA A;  2OFI A;  4EA5 A;  2ABK A;  3IHO A;  1N3A A;  1KG4 A;  1KQJ A;  4YPH A;  1NKU A;  1XG7 A;  4DK9 A;  1DIZ A;  3CVS A;  4OFA A;  5CHZ A;  1WEG A;  2NOI A;  1KG5 A;  3D4V A;  1PVS A;  2JHN A;  2I5W A;  4PII A;  1MUD A;  1WEF A;  1N3C A;  1RRS A;  4B23 A;  3IH7 A;  2NOE A;  1YQR A;  3CW7 A;  1KG2 A;  1NGN A;  3FHG A;  3OH6 A;  1PU6 A;  4EW4 A;  3G0Q A;  2JG6 A;  1P7M A;  5KN8 A;  3N5N X;  4E9H A;  1LWW A;  3CWA A;  4AI4 A;  4YPR A;  4E9G A;  2YG8 A;  1MPG A;  1PU7 A;  4EVV A;  1M3Q A;  1VRL A;  4UOB A;  4E9F A;  3KNT A;  1N39 A;  3F0Z A;  3FSP A;  3FHF A;  4OFH A;  1MUY A;  3CVT A;  2XHI A;  1YQM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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