1KG6A

Crystal structure of the k142r mutant of e.coli muty (core fragment)
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVRRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords A/G-specific adenine glycosylase
total genus 78
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg6A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg6A01
3I0XA 3D4VA 1LWYA 1WEFA 1NKUA 2NOLA 2H56A 4YPRA 3I0WA 4EW0A 1PVSA 3S6IA 1KG3A 1DIZA 4EVVA 1MUNA 1KQJA 1FN7A 3KTUA 2I5WA 1YQRA 4UNFA 1LWWA 1KO9A 3CVSA 5CHZA 4EJZA 1P7MA 1N3CA 5AN4A 4YOQA 3N0UA 3OH6A 4EA4A 5KN8A 4B24A 1KEAA 2JHJA 1YQMA 1RRSA 4HSBA 4E9HA 2JG6A 4AI5A 2XHIA 1XQPA 1KG4A 2NOEA 2YG9A 1ORPA 4AIAA 3FSPA 3G0QA 1XQOA 2OFKA 1KG6A 3N5NX 1MUYA 4OFAA 3FHGA 4EA5A 1MPGA 4YPHA 2JHNA 3OGDA 3F0ZA 4B21A 1KG7A 2YG8A 1RRQA 2NOIA 4EJYA 5KN9A 1MUDA 3CWSA 1P59A 1KG5A 1YQKA 3CW7A 4B23A 3IHOA 1PU6A 4E9GA 3CWUA 1EBMA 3OH9A 3IH7A 4OFEA 5DPKA 4E9FA 1NGNA 2ABKA 3KNTA 1LMZA 4PIIA 1VRLA 3CVTA 3F10A 3FHFA 1M3HA 1XG7A 2NOFA 4E9EA 4B22A 1YQLA 2NOZA 4UOBA 4DK9A 2NOHA 3CWAA 1N39A 1WEIA 1M3QA 1PU8A 3CWTA 4EW4A 1WEGA 1HU0A 2NOBA 1ORNA 1PU7A 1KG2A 4AI4A 1N3AA 1LWVA 2OFIA 4OFHA
chains in the Genus database with same CATH superfamily
3I0XA 3D4VA 4E7HA 4E7JA 1WEFA 1NKUA 1LWYA 3LCNA 2H56A 4YPRA 3I0WA 2NOLA 4EW0A 4BE0A 3OYIA 1PVSA 3S6IA 3S3NA 1KG3A 1DIZA 3OYCA 3R2XC 1MUNA 4EVVA 1KQJA 3VW4A 1FN7A 3KTUA 3NNQA 4BE2A 3OS2A 2I5WA 1YQRA 4UNFA 1LWWA 1KO9A 3CVSA 5CHZA 4EJZA 1P7MA 1N3CA 3L2UA 1U84A 5AN4A 4YOQA 3N0UA 3OH6A 4EA4A 5KN8A 4B24A 1KEAA 2JHJA 3L2VA 1YQMA 1RRSA 4HSBA 4E9HA 2JG6A 4AI5A 2XHIA 1XQPA 1KG4A 2NOEA 2YG9A 3OYAA 1ORPA 4AIAA 3FSPA 3L2RA 3G0QA 1XQOA 2OFKA 1KG6A 3OYJA 4BACA 3N5NX 3S3OA 4BDYA 1MUYA 4OFAA 3OYEA 3L2QA 3FHGA 4EA5A 1MPGA 4YPHA 2JHNA 4E7KA 3F0ZA 5FROA 3OYBA 3OGDA 4B21A 3OS0A 1KG7A 2YG8A 3OS1A 3L2WA 1RRQA 4EJYA 2NOIA 5KN9A 5FRMA 1MUDA 3CWSA 1P59A 1KG5A 4NZGA 3OYNA 4E7LA 1YQKA 3CW7A 4B23A 3IHOA 3OYMA 4BDZA 2V75A 2W03A 3OYKA 5FRNA 1PU6A 4E9GA 3CWUA 1EBMA 3OH9A 3IH7A 4OFEA 5DPKA 4BE1A 4E9FA 1NGNA 3OYLA 2ABKA 3KNTA 1LMZA 4PIIA 1VRLA 3CVTA 3F10A 3FHFA 1M3HA 1XG7A 3OY9A 2NOFA 4E9EA 4B22A 1YQLA 2NOZA 2JPSA 4UOBA 3OYHA 4E7IA 4DK9A 3OYGA 4ZTJA 2NOHA 3CWAA 1N39A 1WEIA 2W04A 3S3MA 1M3QA 1PU8A 3CWTA 4EW4A 1WEGA 1HU0A 3OYDA 2NOBA 1ORNA 1PU7A 4ZTFA 1KG2A 4AI4A 1N3AA 3OYFA 1LWVA 2OFIA 4IKFA 4OFHA
chains in the Genus database with same CATH topology
3I0XA 3D4VA 1LWYA 1WEFA 1NKUA 2NOLA 2H56A 4YPRA 3I0WA 4EW0A 1PVSA 3S6IA 1KG3A 1DIZA 4EVVA 1MUNA 1KQJA 1FN7A 3KTUA 2I5WA 1YQRA 4UNFA 1LWWA 1KO9A 3CVSA 5CHZA 4EJZA 1P7MA 1N3CA 5AN4A 4YOQA 3N0UA 3OH6A 4EA4A 5KN8A 4B24A 1KEAA 2JHJA 1YQMA 1RRSA 4HSBA 4E9HA 2JG6A 4AI5A 2XHIA 1XQPA 1KG4A 2NOEA 2YG9A 1ORPA 4AIAA 3FSPA 3G0QA 1XQOA 2OFKA 1KG6A 3N5NX 1MUYA 4OFAA 3FHGA 4EA5A 1MPGA 4YPHA 2JHNA 3OGDA 3F0ZA 4B21A 1KG7A 2YG8A 1RRQA 2NOIA 4EJYA 5KN9A 1MUDA 3CWSA 1P59A 1KG5A 1YQKA 3CW7A 4B23A 3IHOA 1PU6A 4E9GA 3CWUA 1EBMA 3OH9A 3IH7A 4OFEA 5DPKA 4E9FA 1NGNA 2ABKA 3KNTA 1LMZA 4PIIA 1VRLA 3CVTA 3F10A 3FHFA 1M3HA 1XG7A 2NOFA 4E9EA 4B22A 1YQLA 2NOZA 4UOBA 4DK9A 2NOHA 3CWAA 1N39A 1WEIA 1M3QA 1PU8A 3CWTA 4EW4A 1WEGA 1HU0A 2NOBA 1ORNA 1PU7A 1KG2A 4AI4A 1N3AA 1LWVA 2OFIA 4OFHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I0X A;  3D4V A;  1LWY A;  1WEF A;  1NKU A;  2NOL A;  2H56 A;  4YPR A;  3I0W A;  4EW0 A;  1PVS A;  3S6I A;  1KG3 A;  1DIZ A;  4EVV A;  1MUN A;  1KQJ A;  1FN7 A;  3KTU A;  2I5W A;  1YQR A;  4UNF A;  1LWW A;  1KO9 A;  3CVS A;  5CHZ A;  4EJZ A;  1P7M A;  1N3C A;  5AN4 A;  4YOQ A;  3N0U A;  3OH6 A;  4EA4 A;  5KN8 A;  4B24 A;  1KEA A;  2JHJ A;  1YQM A;  1RRS A;  4HSB A;  4E9H A;  2JG6 A;  4AI5 A;  2XHI A;  1XQP A;  1KG4 A;  2NOE A;  2YG9 A;  1ORP A;  4AIA A;  3FSP A;  3G0Q A;  1XQO A;  2OFK A;  1KG6 A;  3N5N X;  1MUY A;  4OFA A;  3FHG A;  4EA5 A;  1MPG A;  4YPH A;  2JHN A;  3OGD A;  3F0Z A;  4B21 A;  1KG7 A;  2YG8 A;  1RRQ A;  2NOI A;  4EJY A;  5KN9 A;  1MUD A;  3CWS A;  1P59 A;  1KG5 A;  1YQK A;  3CW7 A;  4B23 A;  3IHO A;  1PU6 A;  4E9G A;  3CWU A;  1EBM A;  3OH9 A;  3IH7 A;  4OFE A;  5DPK A;  4E9F A;  1NGN A;  2ABK A;  3KNT A;  1LMZ A;  4PII A;  1VRL A;  3CVT A;  3F10 A;  3FHF A;  1M3H A;  1XG7 A;  2NOF A;  4E9E A;  4B22 A;  1YQL A;  2NOZ A;  4UOB A;  4DK9 A;  2NOH A;  3CWA A;  1N39 A;  1WEI A;  1M3Q A;  1PU8 A;  3CWT A;  4EW4 A;  1WEG A;  1HU0 A;  2NOB A;  1ORN A;  1PU7 A;  1KG2 A;  4AI4 A;  1N3A A;  1LWV A;  2OFI A;  4OFH A; 
#chains in the Genus database with same CATH topology
 3I0X A;  3D4V A;  4E7H A;  4E7J A;  1WEF A;  1NKU A;  1LWY A;  3LCN A;  2H56 A;  4YPR A;  3I0W A;  2NOL A;  4EW0 A;  4BE0 A;  3OYI A;  1PVS A;  3S6I A;  3S3N A;  1KG3 A;  1DIZ A;  3OYC A;  3R2X C;  1MUN A;  4EVV A;  1KQJ A;  3VW4 A;  1FN7 A;  3KTU A;  3NNQ A;  4BE2 A;  3OS2 A;  2I5W A;  1YQR A;  4UNF A;  1LWW A;  1KO9 A;  3CVS A;  5CHZ A;  4EJZ A;  1P7M A;  1N3C A;  3L2U A;  1U84 A;  5AN4 A;  4YOQ A;  3N0U A;  3OH6 A;  4EA4 A;  5KN8 A;  4B24 A;  1KEA A;  2JHJ A;  3L2V A;  1YQM A;  1RRS A;  4HSB A;  4E9H A;  2JG6 A;  4AI5 A;  2XHI A;  1XQP A;  1KG4 A;  2NOE A;  2YG9 A;  3OYA A;  1ORP A;  4AIA A;  3FSP A;  3L2R A;  3G0Q A;  1XQO A;  2OFK A;  1KG6 A;  3OYJ A;  4BAC A;  3N5N X;  3S3O A;  4BDY A;  1MUY A;  4OFA A;  3OYE A;  3L2Q A;  3FHG A;  4EA5 A;  1MPG A;  4YPH A;  2JHN A;  4E7K A;  3F0Z A;  5FRO A;  3OYB A;  3OGD A;  4B21 A;  3OS0 A;  1KG7 A;  2YG8 A;  3OS1 A;  3L2W A;  1RRQ A;  4EJY A;  2NOI A;  5KN9 A;  5FRM A;  1MUD A;  3CWS A;  1P59 A;  1KG5 A;  4NZG A;  3OYN A;  4E7L A;  1YQK A;  3CW7 A;  4B23 A;  3IHO A;  3OYM A;  4BDZ A;  2V75 A;  2W03 A;  3OYK A;  5FRN A;  1PU6 A;  4E9G A;  3CWU A;  1EBM A;  3OH9 A;  3IH7 A;  4OFE A;  5DPK A;  4BE1 A;  4E9F A;  1NGN A;  3OYL A;  2ABK A;  3KNT A;  1LMZ A;  4PII A;  1VRL A;  3CVT A;  3F10 A;  3FHF A;  1M3H A;  1XG7 A;  3OY9 A;  2NOF A;  4E9E A;  4B22 A;  1YQL A;  2NOZ A;  2JPS A;  4UOB A;  3OYH A;  4E7I A;  4DK9 A;  3OYG A;  4ZTJ A;  2NOH A;  3CWA A;  1N39 A;  1WEI A;  2W04 A;  3S3M A;  1M3Q A;  1PU8 A;  3CWT A;  4EW4 A;  1WEG A;  1HU0 A;  3OYD A;  2NOB A;  1ORN A;  1PU7 A;  4ZTF A;  1KG2 A;  4AI4 A;  1N3A A;  3OYF A;  1LWV A;  2OFI A;  4IKF A;  4OFH A; 
#chains in the Genus database with same CATH homology
 3I0X A;  3D4V A;  1LWY A;  1WEF A;  1NKU A;  2NOL A;  2H56 A;  4YPR A;  3I0W A;  4EW0 A;  1PVS A;  3S6I A;  1KG3 A;  1DIZ A;  4EVV A;  1MUN A;  1KQJ A;  1FN7 A;  3KTU A;  2I5W A;  1YQR A;  4UNF A;  1LWW A;  1KO9 A;  3CVS A;  5CHZ A;  4EJZ A;  1P7M A;  1N3C A;  5AN4 A;  4YOQ A;  3N0U A;  3OH6 A;  4EA4 A;  5KN8 A;  4B24 A;  1KEA A;  2JHJ A;  1YQM A;  1RRS A;  4HSB A;  4E9H A;  2JG6 A;  4AI5 A;  2XHI A;  1XQP A;  1KG4 A;  2NOE A;  2YG9 A;  1ORP A;  4AIA A;  3FSP A;  3G0Q A;  1XQO A;  2OFK A;  1KG6 A;  3N5N X;  1MUY A;  4OFA A;  3FHG A;  4EA5 A;  1MPG A;  4YPH A;  2JHN A;  3OGD A;  3F0Z A;  4B21 A;  1KG7 A;  2YG8 A;  1RRQ A;  2NOI A;  4EJY A;  5KN9 A;  1MUD A;  3CWS A;  1P59 A;  1KG5 A;  1YQK A;  3CW7 A;  4B23 A;  3IHO A;  1PU6 A;  4E9G A;  3CWU A;  1EBM A;  3OH9 A;  3IH7 A;  4OFE A;  5DPK A;  4E9F A;  1NGN A;  2ABK A;  3KNT A;  1LMZ A;  4PII A;  1VRL A;  3CVT A;  3F10 A;  3FHF A;  1M3H A;  1XG7 A;  2NOF A;  4E9E A;  4B22 A;  1YQL A;  2NOZ A;  4UOB A;  4DK9 A;  2NOH A;  3CWA A;  1N39 A;  1WEI A;  1M3Q A;  1PU8 A;  3CWT A;  4EW4 A;  1WEG A;  1HU0 A;  2NOB A;  1ORN A;  1PU7 A;  1KG2 A;  4AI4 A;  1N3A A;  1LWV A;  2OFI A;  4OFH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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