1KW2A

Crystal structure of uncomplexed vitamin d-binding protein
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
455
structure length
455
Chain Sequence
GRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPKELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the vitamin D-binding protein and its complex with actin: structural basis of the actin-scavenger system.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Vitamin D-binding protein
total genus 175
structure length 455
sequence length 455
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
A PF09164 VitD-bind_III Vitamin D binding protein, domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A05
1N5UA 2BXNA 2XSIA 4G04A 1J78A 3LU6A 4PO0A 5IJEA 5IIHA 4F5VA 1BM0A 4G03A 1E7HA 2XW1A 2XVUA 4S1YA 4F5TA 3SQJA 1MA9A 4Z69A 3UIVA 1LOTA 3JQZA 4K2CA 2BXEA 2BXAA 3CX9A 1HK5A 5FUOA 2XVWA 2BXGA 4HGMB 2VUEA 2XW0A 3B9MA 3JRYA 1HK1A 4JK4A 2BXFA 3TDLA 2XVQA 1HK4A 2BXHA 1E7EA 4OT2A 1BJ5A 1E78A 2XVVA 2BXCA 3B9LA 5ID7A 4N0UD 2BXLA 3V03A 1E7GA 1UORA 5GHKA 1E7BA 2YDFA 4EMXA 3LU7A 2BX8A 1TF0A 1O9XA 5IJFA 2VDBA 1KXPD 1HA2A 1HK3A 5DQFA 5ID9A 2BXQA 4BKEA 4LB9A 4E99A 3V09A 1AO6A 4J2VA 1BKEA 2BXMA 5IFOA 1J7EA 4LA0A 4IW1A 4IW2A 2BXBA 2VUFA 5DBYA 1E7AA 3V08A 4L8UA 1HK2A 5IIUA 4L9QA 2I2ZA 4ZBQA 4LUHA 4N0FD 2BXPA 4L9KA 1GNIA 1GNJA 4F5SA 2BXKA 3LU8A 2BXDA 1KW2A 1H9ZA 2BXIA 2I30A 5IIXA 1E7IA 3A73A 1E7CA 4HGKA 4LUFA 1E7FA 2BXOA 4OR0A 4F5UA 4ZBRA 5IJ5A 5HOZA 4K71A 4LB2A
chains in the Genus database with same CATH superfamily
1N5UA 2BXNA 2XSIA 4G04A 4FJCB 4OTTA 4FIPB 2QM6A 4MBEC 1J78A 3G9KD 3LU6A 4PO0A 5IJEA 1MM8A 2LXSA 3VQIA 5IIHA 4F5VA 1BM0A 4M70B 4G03A 2DBXA 1E7HA 2KWFA 3KIKA 2Z8JA 2XW1A 1LNSA 2E0YA 2XVUA 4S1YA 4F5TA 3SQJA 2QHBA 3MHSB 1MA9A 2LQIA 4Z69A 3UIVA 1LOTA 3JQZA 1VZSA 4K2CA 2BXEA 1H5WA 2BXAA 2NQOA 3CX9A 1HK5A 4GDXA 5FUOA 2XVWA 3BPJA 2EFEA 3WHQA 2BXGA 2VUEA 4HGMB 2XW0A 3FNMA 4W4UB 4DHXB 3NVKA 1KDXA 4ZC6A 3B9MA 3JRYA 1HK1A 4JK4A 2BXFA 4ZBKA 3TDLA 2ROHA 2QMCA 2XVQA 1HK4A 3PLAA 2BXHA 1E7EA 4OT2A 1BJ5A 1E78A 2XVVA 2DG5A 3GQUA 2BXCA 3NMUA 3B9LA 2JUHA 2Z8IA 5ID7A 4N0UD 1MUHA 2BXLA 3V03A 1E7GA 1UORA 5GHKA 4GDKB 3H3AA 3ECPA 1E7BA 2LQHA 2YDFA 4D7XA 1NT2B 3GA9L 2Z8KA 3H37A 4I9OA 4EMXA 3WHSA 3LU7A 2E0XA 1TXUA 4N3ZA 2DYMA 2BX8A 1TF0A 2DBUA 3WHRA 1MIVA 1O9XA 2V36A 5IJFA 2OT3A 2VDBA 2DYOA 1KXPD 1HA2A 4OTUA 3GQXA 1HK3A 5DQFA 1JNBA 5ID9A 2BXQA 4BKEA 2EFDA 4LB9A 4ZUXV 4E99A 3SIUB 4G01A 1FOUA 5GIOA 2EFHA 1SB0A 4TQ0A 3V09A 1AO6A 4J2VA 4DM0A 2AJEA 1BKEA 2BXMA 1IJGA 5IFOA 2AGHB 4GDLB 1MIYA 1J7EA 3FWCC 3NVMA 2CKXA 4LA0A 4IW1A 4IW2A 5D7GA 2BXBA 2VUFA 2LOQA 4NAWB 2LXTA 2K0NA 3M99C 3MHHB 5GINA 3SIVB 1MUSA 5DBYA 1E7AA 2KBZA 3V08A 2GUTA 4L8UA 4Z9OA 3W1SA 1HK2A 3A75A 5IIUA 2NNWA 4FK5B 4L9QA 5GIPA 5B5TA 1MIWA 2I2ZA 4BY9C 4ZBQA 1VFIA 2XMOA 3ICXA 4LUHA 4N0FD 2DBWA 3KJLA 2BXPA 4L9KA 1GNIA 3FWBC 1GNJA 4F5SA 2BXKA 3LU8A 2BXDA 3NVIA 1KW2A 1H9ZA 2BXIA 2I30A 5IIXA 1E7IA 3A73A 5BPKA 1E7CA 4HGKA 4LUFA 4GG2A 1E7FA 2BXOA 4OR0A 4C31B 4F5UA 4ZBRA 4WA6B 5IJ5A 4TQ1A 5HOZA 4K71A 2EFCA 4LB2A 4ZCGA 2OZBB
chains in the Genus database with same CATH topology
1N5UA 2BXNA 2XSIA 4G04A 4FJCB 4OTTA 4FIPB 2QM6A 4MBEC 1J78A 3G9KD 3LU6A 4PO0A 5IJEA 3VQIA 5IIHA 4F5VA 1BM0A 4M70B 4G03A 2DBXA 1E7HA 3KIKA 2Z8JA 2XW1A 1LNSA 2E0YA 2XVUA 4S1YA 4F5TA 3SQJA 2QHBA 3MHSB 1MA9A 4Z69A 3UIVA 1LOTA 3JQZA 1VZSA 4K2CA 2BXEA 1H5WA 2BXAA 2NQOA 3CX9A 1HK5A 4GDXA 5FUOA 2XVWA 2EFEA 3WHQA 2BXGA 2VUEA 4HGMB 2XW0A 3FNMA 4W4UB 4DHXB 3NVKA 4ZC6A 3B9MA 3JRYA 1HK1A 4JK4A 2BXFA 4ZBKA 3TDLA 2ROHA 2QMCA 2XVQA 1HK4A 3PLAA 2BXHA 1E7EA 4OT2A 1BJ5A 1E78A 2XVVA 2DG5A 3GQUA 2BXCA 3NMUA 3B9LA 2JUHA 2Z8IA 5ID7A 4N0UD 2BXLA 3V03A 1E7GA 1UORA 5GHKA 4GDKB 3H3AA 1E7BA 2YDFA 1NT2B 3GA9L 2Z8KA 3H37A 4EMXA 3WHSA 3LU7A 2E0XA 1TXUA 4N3ZA 2DYMA 2BX8A 1TF0A 2DBUA 3WHRA 1MIVA 1O9XA 2V36A 5IJFA 2OT3A 2VDBA 2DYOA 1KXPD 1HA2A 4OTUA 3GQXA 1HK3A 5DQFA 1JNBA 5ID9A 2BXQA 4BKEA 2EFDA 4LB9A 4ZUXV 4E99A 3SIUB 4G01A 1FOUA 5GIOA 2EFHA 4TQ0A 3V09A 1AO6A 4J2VA 2AJEA 1BKEA 2BXMA 1IJGA 5IFOA 4GDLB 1MIYA 1J7EA 3FWCC 3NVMA 2CKXA 4LA0A 4IW1A 4IW2A 5D7GA 2BXBA 2VUFA 2LOQA 4NAWB 3SIVB 3M99C 3MHHB 5GINA 5DBYA 1E7AA 2KBZA 3V08A 4L8UA 4Z9OA 3W1SA 1HK2A 3A75A 5IIUA 2NNWA 4FK5B 4L9QA 5GIPA 5B5TA 1MIWA 2I2ZA 4BY9C 4ZBQA 1VFIA 2XMOA 3ICXA 4LUHA 4N0FD 2DBWA 3KJLA 2BXPA 4L9KA 1GNIA 3FWBC 1GNJA 4F5SA 2BXKA 3LU8A 2BXDA 3NVIA 1KW2A 1H9ZA 2BXIA 2I30A 5IIXA 1E7IA 3A73A 5BPKA 1E7CA 4HGKA 4LUFA 4GG2A 1E7FA 2BXOA 4OR0A 4C31B 4F5UA 4ZBRA 4WA6B 5IJ5A 4TQ1A 5HOZA 4K71A 2EFCA 4LB2A 4ZCGA 2OZBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N5U A;  2BXN A;  2XSI A;  4G04 A;  1J78 A;  3LU6 A;  4PO0 A;  5IJE A;  5IIH A;  4F5V A;  1BM0 A;  4G03 A;  1E7H A;  2XW1 A;  2XVU A;  4S1Y A;  4F5T A;  3SQJ A;  1MA9 A;  4Z69 A;  3UIV A;  1LOT A;  3JQZ A;  4K2C A;  2BXE A;  2BXA A;  3CX9 A;  1HK5 A;  5FUO A;  2XVW A;  2BXG A;  4HGM B;  2VUE A;  2XW0 A;  3B9M A;  3JRY A;  1HK1 A;  4JK4 A;  2BXF A;  3TDL A;  2XVQ A;  1HK4 A;  2BXH A;  1E7E A;  4OT2 A;  1BJ5 A;  1E78 A;  2XVV A;  2BXC A;  3B9L A;  5ID7 A;  4N0U D;  2BXL A;  3V03 A;  1E7G A;  1UOR A;  5GHK A;  1E7B A;  2YDF A;  4EMX A;  3LU7 A;  2BX8 A;  1TF0 A;  1O9X A;  5IJF A;  2VDB A;  1KXP D;  1HA2 A;  1HK3 A;  5DQF A;  5ID9 A;  2BXQ A;  4BKE A;  4LB9 A;  4E99 A;  3V09 A;  1AO6 A;  4J2V A;  1BKE A;  2BXM A;  5IFO A;  1J7E A;  4LA0 A;  4IW1 A;  4IW2 A;  2BXB A;  2VUF A;  5DBY A;  1E7A A;  3V08 A;  4L8U A;  1HK2 A;  5IIU A;  4L9Q A;  2I2Z A;  4ZBQ A;  4LUH A;  4N0F D;  2BXP A;  4L9K A;  1GNI A;  1GNJ A;  4F5S A;  2BXK A;  3LU8 A;  2BXD A;  1KW2 A;  1H9Z A;  2BXI A;  2I30 A;  5IIX A;  1E7I A;  3A73 A;  1E7C A;  4HGK A;  4LUF A;  1E7F A;  2BXO A;  4OR0 A;  4F5U A;  4ZBR A;  5IJ5 A;  5HOZ A;  4K71 A;  4LB2 A; 
#chains in the Genus database with same CATH topology
 1N5U A;  2BXN A;  2XSI A;  4G04 A;  4FJC B;  4OTT A;  4FIP B;  2QM6 A;  4MBE C;  1J78 A;  3G9K D;  3LU6 A;  4PO0 A;  5IJE A;  1MM8 A;  2LXS A;  3VQI A;  5IIH A;  4F5V A;  1BM0 A;  4M70 B;  4G03 A;  2DBX A;  1E7H A;  2KWF A;  3KIK A;  2Z8J A;  2XW1 A;  1LNS A;  2E0Y A;  2XVU A;  4S1Y A;  4F5T A;  3SQJ A;  2QHB A;  3MHS B;  1MA9 A;  2LQI A;  4Z69 A;  3UIV A;  1LOT A;  3JQZ A;  1VZS A;  4K2C A;  2BXE A;  1H5W A;  2BXA A;  2NQO A;  3CX9 A;  1HK5 A;  4GDX A;  5FUO A;  2XVW A;  3BPJ A;  2EFE A;  3WHQ A;  2BXG A;  2VUE A;  4HGM B;  2XW0 A;  3FNM A;  4W4U B;  4DHX B;  3NVK A;  1KDX A;  4ZC6 A;  3B9M A;  3JRY A;  1HK1 A;  4JK4 A;  2BXF A;  4ZBK A;  3TDL A;  2ROH A;  2QMC A;  2XVQ A;  1HK4 A;  3PLA A;  2BXH A;  1E7E A;  4OT2 A;  1BJ5 A;  1E78 A;  2XVV A;  2DG5 A;  3GQU A;  2BXC A;  3NMU A;  3B9L A;  2JUH A;  2Z8I A;  5ID7 A;  4N0U D;  1MUH A;  2BXL A;  3V03 A;  1E7G A;  1UOR A;  5GHK A;  4GDK B;  3H3A A;  3ECP A;  1E7B A;  2LQH A;  2YDF A;  4D7X A;  1NT2 B;  3GA9 L;  2Z8K A;  3H37 A;  4I9O A;  4EMX A;  3WHS A;  3LU7 A;  2E0X A;  1TXU A;  4N3Z A;  2DYM A;  2BX8 A;  1TF0 A;  2DBU A;  3WHR A;  1MIV A;  1O9X A;  2V36 A;  5IJF A;  2OT3 A;  2VDB A;  2DYO A;  1KXP D;  1HA2 A;  4OTU A;  3GQX A;  1HK3 A;  5DQF A;  1JNB A;  5ID9 A;  2BXQ A;  4BKE A;  2EFD A;  4LB9 A;  4ZUX V;  4E99 A;  3SIU B;  4G01 A;  1FOU A;  5GIO A;  2EFH A;  1SB0 A;  4TQ0 A;  3V09 A;  1AO6 A;  4J2V A;  4DM0 A;  2AJE A;  1BKE A;  2BXM A;  1IJG A;  5IFO A;  2AGH B;  4GDL B;  1MIY A;  1J7E A;  3FWC C;  3NVM A;  2CKX A;  4LA0 A;  4IW1 A;  4IW2 A;  5D7G A;  2BXB A;  2VUF A;  2LOQ A;  4NAW B;  2LXT A;  2K0N A;  3M99 C;  3MHH B;  5GIN A;  3SIV B;  1MUS A;  5DBY A;  1E7A A;  2KBZ A;  3V08 A;  2GUT A;  4L8U A;  4Z9O A;  3W1S A;  1HK2 A;  3A75 A;  5IIU A;  2NNW A;  4FK5 B;  4L9Q A;  5GIP A;  5B5T A;  1MIW A;  2I2Z A;  4BY9 C;  4ZBQ A;  1VFI A;  2XMO A;  3ICX A;  4LUH A;  4N0F D;  2DBW A;  3KJL A;  2BXP A;  4L9K A;  1GNI A;  3FWB C;  1GNJ A;  4F5S A;  2BXK A;  3LU8 A;  2BXD A;  3NVI A;  1KW2 A;  1H9Z A;  2BXI A;  2I30 A;  5IIX A;  1E7I A;  3A73 A;  5BPK A;  1E7C A;  4HGK A;  4LUF A;  4GG2 A;  1E7F A;  2BXO A;  4OR0 A;  4C31 B;  4F5U A;  4ZBR A;  4WA6 B;  5IJ5 A;  4TQ1 A;  5HOZ A;  4K71 A;  2EFC A;  4LB2 A;  4ZCG A;  2OZB B; 
#chains in the Genus database with same CATH homology
 1N5U A;  2BXN A;  2XSI A;  4G04 A;  4FJC B;  4OTT A;  4FIP B;  2QM6 A;  4MBE C;  1J78 A;  3G9K D;  3LU6 A;  4PO0 A;  5IJE A;  3VQI A;  5IIH A;  4F5V A;  1BM0 A;  4M70 B;  4G03 A;  2DBX A;  1E7H A;  3KIK A;  2Z8J A;  2XW1 A;  1LNS A;  2E0Y A;  2XVU A;  4S1Y A;  4F5T A;  3SQJ A;  2QHB A;  3MHS B;  1MA9 A;  4Z69 A;  3UIV A;  1LOT A;  3JQZ A;  1VZS A;  4K2C A;  2BXE A;  1H5W A;  2BXA A;  2NQO A;  3CX9 A;  1HK5 A;  4GDX A;  5FUO A;  2XVW A;  2EFE A;  3WHQ A;  2BXG A;  2VUE A;  4HGM B;  2XW0 A;  3FNM A;  4W4U B;  4DHX B;  3NVK A;  4ZC6 A;  3B9M A;  3JRY A;  1HK1 A;  4JK4 A;  2BXF A;  4ZBK A;  3TDL A;  2ROH A;  2QMC A;  2XVQ A;  1HK4 A;  3PLA A;  2BXH A;  1E7E A;  4OT2 A;  1BJ5 A;  1E78 A;  2XVV A;  2DG5 A;  3GQU A;  2BXC A;  3NMU A;  3B9L A;  2JUH A;  2Z8I A;  5ID7 A;  4N0U D;  2BXL A;  3V03 A;  1E7G A;  1UOR A;  5GHK A;  4GDK B;  3H3A A;  1E7B A;  2YDF A;  1NT2 B;  3GA9 L;  2Z8K A;  3H37 A;  4EMX A;  3WHS A;  3LU7 A;  2E0X A;  1TXU A;  4N3Z A;  2DYM A;  2BX8 A;  1TF0 A;  2DBU A;  3WHR A;  1MIV A;  1O9X A;  2V36 A;  5IJF A;  2OT3 A;  2VDB A;  2DYO A;  1KXP D;  1HA2 A;  4OTU A;  3GQX A;  1HK3 A;  5DQF A;  1JNB A;  5ID9 A;  2BXQ A;  4BKE A;  2EFD A;  4LB9 A;  4ZUX V;  4E99 A;  3SIU B;  4G01 A;  1FOU A;  5GIO A;  2EFH A;  4TQ0 A;  3V09 A;  1AO6 A;  4J2V A;  2AJE A;  1BKE A;  2BXM A;  1IJG A;  5IFO A;  4GDL B;  1MIY A;  1J7E A;  3FWC C;  3NVM A;  2CKX A;  4LA0 A;  4IW1 A;  4IW2 A;  5D7G A;  2BXB A;  2VUF A;  2LOQ A;  4NAW B;  3SIV B;  3M99 C;  3MHH B;  5GIN A;  5DBY A;  1E7A A;  2KBZ A;  3V08 A;  4L8U A;  4Z9O A;  3W1S A;  1HK2 A;  3A75 A;  5IIU A;  2NNW A;  4FK5 B;  4L9Q A;  5GIP A;  5B5T A;  1MIW A;  2I2Z A;  4BY9 C;  4ZBQ A;  1VFI A;  2XMO A;  3ICX A;  4LUH A;  4N0F D;  2DBW A;  3KJL A;  2BXP A;  4L9K A;  1GNI A;  3FWB C;  1GNJ A;  4F5S A;  2BXK A;  3LU8 A;  2BXD A;  3NVI A;  1KW2 A;  1H9Z A;  2BXI A;  2I30 A;  5IIX A;  1E7I A;  3A73 A;  5BPK A;  1E7C A;  4HGK A;  4LUF A;  4GG2 A;  1E7F A;  2BXO A;  4OR0 A;  4C31 B;  4F5U A;  4ZBR A;  4WA6 B;  5IJ5 A;  4TQ1 A;  5HOZ A;  4K71 A;  2EFC A;  4LB2 A;  4ZCG A;  2OZB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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