1NGNA

Mismatch repair in methylated dna. structure of the mismatch-specific thymine glycosylase domain of methyl-cpg-binding protein mbd4
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
144
structure length
144
Chain Sequence
KWTPPRSPFNLVQEILFHDPWKLLIATIFLNRTSGKMAIPVLWEFLEKYPSAEVARAADWRDVSELLKPLGLYDLRAKTIIKFSDEYLTKQWRYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
pubmed doi rcsb
molecule tags Dna binding protein
source organism Mus musculus
molecule keywords methyl-CpG binding protein MBD4
total genus 51
structure length 144
sequence length 144
ec nomenclature
pdb deposition date 2002-12-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1ngnA00
1KG6A 3I0WA 1FN7A 1LWYA 3G0QA 4EVVA 5AN4A 1VRLA 1MUYA 3CWUA 1LMZA 1XQOA 3I0XA 3CWSA 3OH9A 1YQMA 4B22A 2YG9A 1XQPA 3F10A 4EJZA 2NOLA 2NOIA 3CWAA 1P7MA 1WEFA 1YQRA 5KN8A 3KNTA 4AIAA 4HSBA 4OFAA 1KO9A 2NOFA 5KN9A 3F0ZA 4YOQA 1PU6A 1N39A 1KQJA 2H56A 4B24A 1HU0A 4EA4A 1WEGA 3CVSA 3IH7A 1EBMA 1KG4A 4OFEA 1LWVA 4E9FA 1YQLA 5CHZA 4EW4A 4UNFA 2NOBA 4E9EA 4B21A 3S6IA 1KG7A 4E9HA 1PU7A 1KEAA 2JHJA 1WEIA 2JHNA 3IHOA 1P59A 1N3AA 1MUNA 2XHIA 3CVTA 4EW0A 4DK9A 1YQKA 1KG2A 2NOEA 2ABKA 3OH6A 3FSPA 3CW7A 1MUDA 3KTUA 1NGNA 4EA5A 4E9GA 1PU8A 1ORNA 1M3HA 3OGDA 2I5WA 2NOZA 4EJYA 2JG6A 1NKUA 1MPGA 3N0UA 3CWTA 3N5NX 1XG7A 3D4VA 1KG5A 2NOHA 4UOBA 2OFIA 4PIIA 2OFKA 4YPRA 3FHGA 4OFHA 5DPKA 1RRQA 4YPHA 4B23A 1LWWA 1PVSA 4AI5A 1DIZA 3FHFA 1M3QA 1N3CA 1RRSA 4AI4A 1KG3A 2YG8A 1ORPA
chains in the Genus database with same CATH superfamily
1KG6A 3I0WA 1FN7A 1LWYA 3L2QA 3G0QA 4EVVA 3OYFA 5AN4A 1VRLA 1MUYA 3CWUA 3OYKA 1LMZA 1XQOA 3S3NA 3I0XA 3CWSA 3OH9A 1YQMA 4B22A 3OS2A 2YG9A 1XQPA 3F10A 4EJZA 2NOLA 2NOIA 3CWAA 1P7MA 1WEFA 3L2RA 1YQRA 5KN8A 2W03A 3KNTA 4AIAA 4ZTJA 3OYHA 4HSBA 4OFAA 1KO9A 2NOFA 5KN9A 3F0ZA 4YOQA 1U84A 3OYDA 1PU6A 4ZTFA 1N39A 1KQJA 2H56A 4B24A 1HU0A 4EA4A 1WEGA 3CVSA 3IH7A 3OYBA 1EBMA 1KG4A 4OFEA 2JPSA 1LWVA 4E9FA 1YQLA 3VW4A 5CHZA 3OYNA 4EW4A 4UNFA 3L2VA 2NOBA 4E7KA 4E9EA 4B21A 3S6IA 1KG7A 3OS0A 4BE1A 4E9HA 1PU7A 1KEAA 2JHJA 1WEIA 4E7LA 2JHNA 3IHOA 3CW7A 4E7JA 1P59A 1N3AA 3OYEA 1MUNA 2XHIA 3CVTA 5FRNA 3OYLA 3OYCA 3LCNA 4EW0A 4DK9A 1YQKA 1KG2A 2NOEA 2ABKA 3OH6A 3OYAA 3FSPA 4BE0A 1MUDA 3KTUA 4NZGA 1NGNA 3OYGA 3OYMA 4BE2A 4EA5A 1PU8A 2V75A 3OYIA 4E9GA 1M3HA 3OGDA 1ORNA 2I5WA 2W04A 2NOZA 4EJYA 2JG6A 1NKUA 5FROA 3S3OA 1MPGA 3N0UA 3L2UA 3N5NX 3CWTA 1XG7A 3OY9A 3D4VA 1KG5A 2NOHA 3R2XC 4UOBA 2OFIA 4PIIA 2OFKA 4YPRA 4BACA 3FHGA 4OFHA 4BDZA 3OS1A 5DPKA 3S3MA 1RRQA 4IKFA 4YPHA 3NNQA 4B23A 4E7HA 1LWWA 1PVSA 4AI5A 1DIZA 5FRMA 3OYJA 3FHFA 1M3QA 1N3CA 1RRSA 4AI4A 3L2WA 1KG3A 4E7IA 2YG8A 1ORPA 4BDYA
chains in the Genus database with same CATH topology
1KG6A 3I0WA 1FN7A 1LWYA 3G0QA 4EVVA 5AN4A 1VRLA 1MUYA 3CWUA 1LMZA 1XQOA 3I0XA 3CWSA 3OH9A 1YQMA 4B22A 2YG9A 1XQPA 3F10A 4EJZA 2NOLA 2NOIA 3CWAA 1P7MA 1WEFA 1YQRA 5KN8A 3KNTA 4AIAA 4HSBA 4OFAA 1KO9A 2NOFA 5KN9A 3F0ZA 4YOQA 1PU6A 1N39A 1KQJA 2H56A 4B24A 1HU0A 4EA4A 1WEGA 3CVSA 3IH7A 1EBMA 1KG4A 4OFEA 1LWVA 4E9FA 1YQLA 5CHZA 4EW4A 4UNFA 2NOBA 4E9EA 4B21A 3S6IA 1KG7A 4E9HA 1PU7A 1KEAA 2JHJA 1WEIA 2JHNA 3IHOA 1P59A 1N3AA 1MUNA 2XHIA 3CVTA 4EW0A 4DK9A 1YQKA 1KG2A 2NOEA 2ABKA 3OH6A 3FSPA 3CW7A 1MUDA 3KTUA 1NGNA 4EA5A 4E9GA 1PU8A 1ORNA 1M3HA 3OGDA 2I5WA 2NOZA 4EJYA 2JG6A 1NKUA 1MPGA 3N0UA 3CWTA 3N5NX 1XG7A 3D4VA 1KG5A 2NOHA 4UOBA 2OFIA 4PIIA 2OFKA 4YPRA 3FHGA 4OFHA 5DPKA 1RRQA 4YPHA 4B23A 1LWWA 1PVSA 4AI5A 1DIZA 3FHFA 1M3QA 1N3CA 1RRSA 4AI4A 1KG3A 2YG8A 1ORPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KG6 A;  3I0W A;  1FN7 A;  1LWY A;  3G0Q A;  4EVV A;  5AN4 A;  1VRL A;  1MUY A;  3CWU A;  1LMZ A;  1XQO A;  3I0X A;  3CWS A;  3OH9 A;  1YQM A;  4B22 A;  2YG9 A;  1XQP A;  3F10 A;  4EJZ A;  2NOL A;  2NOI A;  3CWA A;  1P7M A;  1WEF A;  1YQR A;  5KN8 A;  3KNT A;  4AIA A;  4HSB A;  4OFA A;  1KO9 A;  2NOF A;  5KN9 A;  3F0Z A;  4YOQ A;  1PU6 A;  1N39 A;  1KQJ A;  2H56 A;  4B24 A;  1HU0 A;  4EA4 A;  1WEG A;  3CVS A;  3IH7 A;  1EBM A;  1KG4 A;  4OFE A;  1LWV A;  4E9F A;  1YQL A;  5CHZ A;  4EW4 A;  4UNF A;  2NOB A;  4E9E A;  4B21 A;  3S6I A;  1KG7 A;  4E9H A;  1PU7 A;  1KEA A;  2JHJ A;  1WEI A;  2JHN A;  3IHO A;  1P59 A;  1N3A A;  1MUN A;  2XHI A;  3CVT A;  4EW0 A;  4DK9 A;  1YQK A;  1KG2 A;  2NOE A;  2ABK A;  3OH6 A;  3FSP A;  3CW7 A;  1MUD A;  3KTU A;  1NGN A;  4EA5 A;  4E9G A;  1PU8 A;  1ORN A;  1M3H A;  3OGD A;  2I5W A;  2NOZ A;  4EJY A;  2JG6 A;  1NKU A;  1MPG A;  3N0U A;  3CWT A;  3N5N X;  1XG7 A;  3D4V A;  1KG5 A;  2NOH A;  4UOB A;  2OFI A;  4PII A;  2OFK A;  4YPR A;  3FHG A;  4OFH A;  5DPK A;  1RRQ A;  4YPH A;  4B23 A;  1LWW A;  1PVS A;  4AI5 A;  1DIZ A;  3FHF A;  1M3Q A;  1N3C A;  1RRS A;  4AI4 A;  1KG3 A;  2YG8 A;  1ORP A; 
#chains in the Genus database with same CATH topology
 1KG6 A;  3I0W A;  1FN7 A;  1LWY A;  3L2Q A;  3G0Q A;  4EVV A;  3OYF A;  5AN4 A;  1VRL A;  1MUY A;  3CWU A;  3OYK A;  1LMZ A;  1XQO A;  3S3N A;  3I0X A;  3CWS A;  3OH9 A;  1YQM A;  4B22 A;  3OS2 A;  2YG9 A;  1XQP A;  3F10 A;  4EJZ A;  2NOL A;  2NOI A;  3CWA A;  1P7M A;  1WEF A;  3L2R A;  1YQR A;  5KN8 A;  2W03 A;  3KNT A;  4AIA A;  4ZTJ A;  3OYH A;  4HSB A;  4OFA A;  1KO9 A;  2NOF A;  5KN9 A;  3F0Z A;  4YOQ A;  1U84 A;  3OYD A;  1PU6 A;  4ZTF A;  1N39 A;  1KQJ A;  2H56 A;  4B24 A;  1HU0 A;  4EA4 A;  1WEG A;  3CVS A;  3IH7 A;  3OYB A;  1EBM A;  1KG4 A;  4OFE A;  2JPS A;  1LWV A;  4E9F A;  1YQL A;  3VW4 A;  5CHZ A;  3OYN A;  4EW4 A;  4UNF A;  3L2V A;  2NOB A;  4E7K A;  4E9E A;  4B21 A;  3S6I A;  1KG7 A;  3OS0 A;  4BE1 A;  4E9H A;  1PU7 A;  1KEA A;  2JHJ A;  1WEI A;  4E7L A;  2JHN A;  3IHO A;  3CW7 A;  4E7J A;  1P59 A;  1N3A A;  3OYE A;  1MUN A;  2XHI A;  3CVT A;  5FRN A;  3OYL A;  3OYC A;  3LCN A;  4EW0 A;  4DK9 A;  1YQK A;  1KG2 A;  2NOE A;  2ABK A;  3OH6 A;  3OYA A;  3FSP A;  4BE0 A;  1MUD A;  3KTU A;  4NZG A;  1NGN A;  3OYG A;  3OYM A;  4BE2 A;  4EA5 A;  1PU8 A;  2V75 A;  3OYI A;  4E9G A;  1M3H A;  3OGD A;  1ORN A;  2I5W A;  2W04 A;  2NOZ A;  4EJY A;  2JG6 A;  1NKU A;  5FRO A;  3S3O A;  1MPG A;  3N0U A;  3L2U A;  3N5N X;  3CWT A;  1XG7 A;  3OY9 A;  3D4V A;  1KG5 A;  2NOH A;  3R2X C;  4UOB A;  2OFI A;  4PII A;  2OFK A;  4YPR A;  4BAC A;  3FHG A;  4OFH A;  4BDZ A;  3OS1 A;  5DPK A;  3S3M A;  1RRQ A;  4IKF A;  4YPH A;  3NNQ A;  4B23 A;  4E7H A;  1LWW A;  1PVS A;  4AI5 A;  1DIZ A;  5FRM A;  3OYJ A;  3FHF A;  1M3Q A;  1N3C A;  1RRS A;  4AI4 A;  3L2W A;  1KG3 A;  4E7I A;  2YG8 A;  1ORP A;  4BDY A; 
#chains in the Genus database with same CATH homology
 1KG6 A;  3I0W A;  1FN7 A;  1LWY A;  3G0Q A;  4EVV A;  5AN4 A;  1VRL A;  1MUY A;  3CWU A;  1LMZ A;  1XQO A;  3I0X A;  3CWS A;  3OH9 A;  1YQM A;  4B22 A;  2YG9 A;  1XQP A;  3F10 A;  4EJZ A;  2NOL A;  2NOI A;  3CWA A;  1P7M A;  1WEF A;  1YQR A;  5KN8 A;  3KNT A;  4AIA A;  4HSB A;  4OFA A;  1KO9 A;  2NOF A;  5KN9 A;  3F0Z A;  4YOQ A;  1PU6 A;  1N39 A;  1KQJ A;  2H56 A;  4B24 A;  1HU0 A;  4EA4 A;  1WEG A;  3CVS A;  3IH7 A;  1EBM A;  1KG4 A;  4OFE A;  1LWV A;  4E9F A;  1YQL A;  5CHZ A;  4EW4 A;  4UNF A;  2NOB A;  4E9E A;  4B21 A;  3S6I A;  1KG7 A;  4E9H A;  1PU7 A;  1KEA A;  2JHJ A;  1WEI A;  2JHN A;  3IHO A;  1P59 A;  1N3A A;  1MUN A;  2XHI A;  3CVT A;  4EW0 A;  4DK9 A;  1YQK A;  1KG2 A;  2NOE A;  2ABK A;  3OH6 A;  3FSP A;  3CW7 A;  1MUD A;  3KTU A;  1NGN A;  4EA5 A;  4E9G A;  1PU8 A;  1ORN A;  1M3H A;  3OGD A;  2I5W A;  2NOZ A;  4EJY A;  2JG6 A;  1NKU A;  1MPG A;  3N0U A;  3CWT A;  3N5N X;  1XG7 A;  3D4V A;  1KG5 A;  2NOH A;  4UOB A;  2OFI A;  4PII A;  2OFK A;  4YPR A;  3FHG A;  4OFH A;  5DPK A;  1RRQ A;  4YPH A;  4B23 A;  1LWW A;  1PVS A;  4AI5 A;  1DIZ A;  3FHF A;  1M3Q A;  1N3C A;  1RRS A;  4AI4 A;  1KG3 A;  2YG8 A;  1ORP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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