1P7MA

Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine dna glycosylase i
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
187
structure length
187
Chain Sequence
MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGLSWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAYLQMEQNGEPFADFVWSFVNHQPQMTQATTLSEIPTSTPASDALSKALKKRGFKFVGTTICYSFMQACGLVNDHVVGCCCYPGNKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase I
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase I
total genus 50
structure length 187
sequence length 187
ec nomenclature ec 3.2.2.20: DNA-3-methyladenine glycosylase I.
pdb deposition date 2003-05-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03352 Adenine_glyco Methyladenine glycosylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1p7mA00
1M3HA 3F0ZA 1XQPA 1DIZA 2YG8A 1VRLA 4EVVA 1MUDA 4OFEA 4B24A 3FHGA 3I0WA 1LMZA 3N0UA 1YQRA 3CW7A 1PU7A 1KG4A 3KTUA 1KG7A 5AN4A 5KN8A 4EA4A 1RRSA 2NOZA 1KG5A 1XQOA 1N39A 2NOBA 4AI5A 2XHIA 5CHZA 1N3AA 4EA5A 1PU8A 1PVSA 4YOQA 2ABKA 4B21A 1LWWA 4EJYA 2H56A 2JHJA 4UNFA 1KO9A 3D4VA 3OH6A 1YQKA 4UOBA 3OH9A 3S6IA 1KQJA 1M3QA 1LWYA 1ORPA 1KG3A 1YQMA 4YPHA 4AI4A 3CWTA 1EBMA 1P7MA 3OGDA 2NOLA 2NOIA 3CWSA 5DPKA 1ORNA 3IHOA 1KG2A 3IH7A 3N5NX 4B23A 3FSPA 2JG6A 1WEIA 3CWAA 1RRQA 2JHNA 1KEAA 3G0QA 3KNTA 5KN9A 1HU0A 4HSBA 1LWVA 4EJZA 1MUNA 1N3CA 2OFIA 2NOEA 1NGNA 2OFKA 1MPGA 1NKUA 3I0XA 4EW4A 4E9FA 4E9GA 3CVTA 1WEGA 2YG9A 1MUYA 1XG7A 1KG6A 4E9EA 4DK9A 1P59A 4YPRA 2NOFA 1FN7A 4OFAA 4B22A 1WEFA 4PIIA 4EW0A 2I5WA 4E9HA 3F10A 1YQLA 4OFHA 3CWUA 4AIAA 3FHFA 3CVSA 1PU6A 2NOHA
chains in the Genus database with same CATH superfamily
3OYAA 1M3HA 3R2XC 3F0ZA 3OYKA 1XQPA 1DIZA 2YG8A 1VRLA 4EVVA 1MUDA 2W03A 4OFEA 4B24A 3FHGA 3I0WA 1LMZA 3N0UA 3S3NA 1YQRA 3CW7A 1PU7A 1KG4A 3KTUA 4E7LA 1KG7A 5AN4A 5KN8A 4EA4A 1RRSA 2NOZA 1KG5A 1XQOA 1N39A 2NOBA 4AI5A 2XHIA 5CHZA 3S3OA 1N3AA 4EA5A 1PU8A 1PVSA 3L2RA 3L2WA 4YOQA 2ABKA 4B21A 3OYGA 4NZGA 1LWWA 4EJYA 2H56A 2JHJA 4UNFA 3OYEA 4BE2A 1KO9A 3D4VA 3OYBA 3S3MA 3OH6A 1YQKA 4UOBA 3OYJA 3OH9A 3S6IA 2JPSA 1KQJA 5FRMA 3OYIA 3OYMA 3OS0A 3L2VA 4E7HA 1M3QA 1LWYA 4BACA 1ORPA 4ZTFA 4BE1A 4BE0A 1KG3A 1YQMA 4YPHA 4AI4A 3CWTA 1EBMA 1P7MA 3OGDA 2NOLA 2NOIA 3CWSA 5DPKA 1ORNA 3IHOA 1KG2A 3OYFA 3IH7A 4ZTJA 3N5NX 4B23A 3FSPA 2JG6A 3LCNA 4IKFA 3OY9A 1WEIA 1U84A 3CWAA 1RRQA 2JHNA 1KEAA 5FROA 3L2QA 3G0QA 3KNTA 5KN9A 1HU0A 3L2UA 2W04A 4HSBA 1LWVA 5FRNA 4EJZA 1MUNA 1N3CA 2OFIA 4BDZA 2NOEA 1NGNA 2OFKA 1MPGA 1NKUA 3I0XA 4EW4A 3VW4A 3NNQA 4E9FA 4E9GA 3OYCA 3CVTA 1WEGA 2YG9A 1MUYA 1XG7A 1KG6A 4E9EA 4DK9A 1P59A 4YPRA 4E7KA 2NOFA 4E7JA 3OYLA 1FN7A 4OFAA 4B22A 1WEFA 4PIIA 4EW0A 2I5WA 3OYHA 3OS1A 4E9HA 4BDYA 3F10A 2V75A 1YQLA 3OYNA 4OFHA 3CWUA 4E7IA 4AIAA 3FHFA 3CVSA 1PU6A 3OYDA 2NOHA 3OS2A
chains in the Genus database with same CATH topology
1M3HA 3F0ZA 1XQPA 1DIZA 2YG8A 1VRLA 4EVVA 1MUDA 4OFEA 4B24A 3FHGA 3I0WA 1LMZA 3N0UA 1YQRA 3CW7A 1PU7A 1KG4A 3KTUA 1KG7A 5AN4A 5KN8A 4EA4A 1RRSA 2NOZA 1KG5A 1XQOA 1N39A 2NOBA 4AI5A 2XHIA 5CHZA 1N3AA 4EA5A 1PU8A 1PVSA 4YOQA 2ABKA 4B21A 1LWWA 4EJYA 2H56A 2JHJA 4UNFA 1KO9A 3D4VA 3OH6A 1YQKA 4UOBA 3OH9A 3S6IA 1KQJA 1M3QA 1LWYA 1ORPA 1KG3A 1YQMA 4YPHA 4AI4A 3CWTA 1EBMA 1P7MA 3OGDA 2NOLA 2NOIA 3CWSA 5DPKA 1ORNA 3IHOA 1KG2A 3IH7A 3N5NX 4B23A 3FSPA 2JG6A 1WEIA 3CWAA 1RRQA 2JHNA 1KEAA 3G0QA 3KNTA 5KN9A 1HU0A 4HSBA 1LWVA 4EJZA 1MUNA 1N3CA 2OFIA 2NOEA 1NGNA 2OFKA 1MPGA 1NKUA 3I0XA 4EW4A 4E9FA 4E9GA 3CVTA 1WEGA 2YG9A 1MUYA 1XG7A 1KG6A 4E9EA 4DK9A 1P59A 4YPRA 2NOFA 1FN7A 4OFAA 4B22A 1WEFA 4PIIA 4EW0A 2I5WA 4E9HA 3F10A 1YQLA 4OFHA 3CWUA 4AIAA 3FHFA 3CVSA 1PU6A 2NOHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M3H A;  3F0Z A;  1XQP A;  1DIZ A;  2YG8 A;  1VRL A;  4EVV A;  1MUD A;  4OFE A;  4B24 A;  3FHG A;  3I0W A;  1LMZ A;  3N0U A;  1YQR A;  3CW7 A;  1PU7 A;  1KG4 A;  3KTU A;  1KG7 A;  5AN4 A;  5KN8 A;  4EA4 A;  1RRS A;  2NOZ A;  1KG5 A;  1XQO A;  1N39 A;  2NOB A;  4AI5 A;  2XHI A;  5CHZ A;  1N3A A;  4EA5 A;  1PU8 A;  1PVS A;  4YOQ A;  2ABK A;  4B21 A;  1LWW A;  4EJY A;  2H56 A;  2JHJ A;  4UNF A;  1KO9 A;  3D4V A;  3OH6 A;  1YQK A;  4UOB A;  3OH9 A;  3S6I A;  1KQJ A;  1M3Q A;  1LWY A;  1ORP A;  1KG3 A;  1YQM A;  4YPH A;  4AI4 A;  3CWT A;  1EBM A;  1P7M A;  3OGD A;  2NOL A;  2NOI A;  3CWS A;  5DPK A;  1ORN A;  3IHO A;  1KG2 A;  3IH7 A;  3N5N X;  4B23 A;  3FSP A;  2JG6 A;  1WEI A;  3CWA A;  1RRQ A;  2JHN A;  1KEA A;  3G0Q A;  3KNT A;  5KN9 A;  1HU0 A;  4HSB A;  1LWV A;  4EJZ A;  1MUN A;  1N3C A;  2OFI A;  2NOE A;  1NGN A;  2OFK A;  1MPG A;  1NKU A;  3I0X A;  4EW4 A;  4E9F A;  4E9G A;  3CVT A;  1WEG A;  2YG9 A;  1MUY A;  1XG7 A;  1KG6 A;  4E9E A;  4DK9 A;  1P59 A;  4YPR A;  2NOF A;  1FN7 A;  4OFA A;  4B22 A;  1WEF A;  4PII A;  4EW0 A;  2I5W A;  4E9H A;  3F10 A;  1YQL A;  4OFH A;  3CWU A;  4AIA A;  3FHF A;  3CVS A;  1PU6 A;  2NOH A; 
#chains in the Genus database with same CATH topology
 3OYA A;  1M3H A;  3R2X C;  3F0Z A;  3OYK A;  1XQP A;  1DIZ A;  2YG8 A;  1VRL A;  4EVV A;  1MUD A;  2W03 A;  4OFE A;  4B24 A;  3FHG A;  3I0W A;  1LMZ A;  3N0U A;  3S3N A;  1YQR A;  3CW7 A;  1PU7 A;  1KG4 A;  3KTU A;  4E7L A;  1KG7 A;  5AN4 A;  5KN8 A;  4EA4 A;  1RRS A;  2NOZ A;  1KG5 A;  1XQO A;  1N39 A;  2NOB A;  4AI5 A;  2XHI A;  5CHZ A;  3S3O A;  1N3A A;  4EA5 A;  1PU8 A;  1PVS A;  3L2R A;  3L2W A;  4YOQ A;  2ABK A;  4B21 A;  3OYG A;  4NZG A;  1LWW A;  4EJY A;  2H56 A;  2JHJ A;  4UNF A;  3OYE A;  4BE2 A;  1KO9 A;  3D4V A;  3OYB A;  3S3M A;  3OH6 A;  1YQK A;  4UOB A;  3OYJ A;  3OH9 A;  3S6I A;  2JPS A;  1KQJ A;  5FRM A;  3OYI A;  3OYM A;  3OS0 A;  3L2V A;  4E7H A;  1M3Q A;  1LWY A;  4BAC A;  1ORP A;  4ZTF A;  4BE1 A;  4BE0 A;  1KG3 A;  1YQM A;  4YPH A;  4AI4 A;  3CWT A;  1EBM A;  1P7M A;  3OGD A;  2NOL A;  2NOI A;  3CWS A;  5DPK A;  1ORN A;  3IHO A;  1KG2 A;  3OYF A;  3IH7 A;  4ZTJ A;  3N5N X;  4B23 A;  3FSP A;  2JG6 A;  3LCN A;  4IKF A;  3OY9 A;  1WEI A;  1U84 A;  3CWA A;  1RRQ A;  2JHN A;  1KEA A;  5FRO A;  3L2Q A;  3G0Q A;  3KNT A;  5KN9 A;  1HU0 A;  3L2U A;  2W04 A;  4HSB A;  1LWV A;  5FRN A;  4EJZ A;  1MUN A;  1N3C A;  2OFI A;  4BDZ A;  2NOE A;  1NGN A;  2OFK A;  1MPG A;  1NKU A;  3I0X A;  4EW4 A;  3VW4 A;  3NNQ A;  4E9F A;  4E9G A;  3OYC A;  3CVT A;  1WEG A;  2YG9 A;  1MUY A;  1XG7 A;  1KG6 A;  4E9E A;  4DK9 A;  1P59 A;  4YPR A;  4E7K A;  2NOF A;  4E7J A;  3OYL A;  1FN7 A;  4OFA A;  4B22 A;  1WEF A;  4PII A;  4EW0 A;  2I5W A;  3OYH A;  3OS1 A;  4E9H A;  4BDY A;  3F10 A;  2V75 A;  1YQL A;  3OYN A;  4OFH A;  3CWU A;  4E7I A;  4AIA A;  3FHF A;  3CVS A;  1PU6 A;  3OYD A;  2NOH A;  3OS2 A; 
#chains in the Genus database with same CATH homology
 1M3H A;  3F0Z A;  1XQP A;  1DIZ A;  2YG8 A;  1VRL A;  4EVV A;  1MUD A;  4OFE A;  4B24 A;  3FHG A;  3I0W A;  1LMZ A;  3N0U A;  1YQR A;  3CW7 A;  1PU7 A;  1KG4 A;  3KTU A;  1KG7 A;  5AN4 A;  5KN8 A;  4EA4 A;  1RRS A;  2NOZ A;  1KG5 A;  1XQO A;  1N39 A;  2NOB A;  4AI5 A;  2XHI A;  5CHZ A;  1N3A A;  4EA5 A;  1PU8 A;  1PVS A;  4YOQ A;  2ABK A;  4B21 A;  1LWW A;  4EJY A;  2H56 A;  2JHJ A;  4UNF A;  1KO9 A;  3D4V A;  3OH6 A;  1YQK A;  4UOB A;  3OH9 A;  3S6I A;  1KQJ A;  1M3Q A;  1LWY A;  1ORP A;  1KG3 A;  1YQM A;  4YPH A;  4AI4 A;  3CWT A;  1EBM A;  1P7M A;  3OGD A;  2NOL A;  2NOI A;  3CWS A;  5DPK A;  1ORN A;  3IHO A;  1KG2 A;  3IH7 A;  3N5N X;  4B23 A;  3FSP A;  2JG6 A;  1WEI A;  3CWA A;  1RRQ A;  2JHN A;  1KEA A;  3G0Q A;  3KNT A;  5KN9 A;  1HU0 A;  4HSB A;  1LWV A;  4EJZ A;  1MUN A;  1N3C A;  2OFI A;  2NOE A;  1NGN A;  2OFK A;  1MPG A;  1NKU A;  3I0X A;  4EW4 A;  4E9F A;  4E9G A;  3CVT A;  1WEG A;  2YG9 A;  1MUY A;  1XG7 A;  1KG6 A;  4E9E A;  4DK9 A;  1P59 A;  4YPR A;  2NOF A;  1FN7 A;  4OFA A;  4B22 A;  1WEF A;  4PII A;  4EW0 A;  2I5W A;  4E9H A;  3F10 A;  1YQL A;  4OFH A;  3CWU A;  4AIA A;  3FHF A;  3CVS A;  1PU6 A;  2NOH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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