1PU8A

Crystal structure of h.pylori 3-methyladenine dna glycosylase (magiii) bound to 1,n6-ethenoadenine
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
215
structure length
214
Chain Sequence
LDSFEILKALKSLDLLKNAPAWWWPNALKFEALLGAVLTQNTKFEAVLKSLENLKNAFILENDDEINLKKIAYIEFSKLAECVRPSGFYNQKAKRLIDLSGNILKDFQSFENFKQEVTREWLLDQKGIGKESADAILCYACAKEVMVVDKYSYLFLKKLGIEIEDYDELQHFFEKGVQENLNSALALYENTISLAQLYARFHGIVEFSKQKLEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases
pubmed doi rcsb
molecule tags Hydrolase
source organism Helicobacter pylori
molecule keywords 3-METHYLADENINE DNA GLYCOSYLASE
total genus 85
structure length 214
sequence length 215
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1pu8A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1pu8A01
2H56A 1NGNA 1PU6A 3N0UA 1YQLA 3IHOA 3FSPA 1RRQA 3OH6A 4UOBA 1KG5A 3FHGA 1YQKA 4EA4A 1M3HA 1NKUA 3F0ZA 4E9FA 1MPGA 2JG6A 4YOQA 2XHIA 1YQRA 5CHZA 4E9GA 3S6IA 4B24A 1KG3A 1LWYA 1YQMA 1N39A 2ABKA 1P7MA 1PU8A 1ORPA 2YG8A 2NOBA 1KG2A 4E9EA 4EVVA 1KQJA 3I0XA 4AI5A 4OFEA 2OFKA 4OFAA 4B21A 4OFHA 1KEAA 4B23A 1PU7A 1LWWA 2I5WA 1MUDA 4PIIA 2YG9A 1ORNA 4EJZA 2NOHA 1LWVA 3CVTA 3I0WA 1FN7A 1WEFA 3OH9A 2NOEA 1XG7A 1KG4A 5AN4A 4HSBA 3N5NX 5KN9A 3D4VA 3IH7A 1WEGA 1XQPA 1VRLA 3CVSA 1RRSA 3CW7A 2JHJA 1DIZA 1LMZA 4AIAA 3OGDA 4EA5A 1KG6A 4YPRA 1KO9A 2NOIA 1WEIA 2NOFA 1P59A 5KN8A 4UNFA 4B22A 1HU0A 2NOLA 1MUYA 4AI4A 4EW4A 3CWUA 5DPKA 1EBMA 3KNTA 4EJYA 1XQOA 3FHFA 2NOZA 4DK9A 1N3CA 1M3QA 4EW0A 4YPHA 1KG7A 2JHNA 3CWSA 4E9HA 2OFIA 1MUNA 1PVSA 3CWAA 3CWTA 3F10A 3G0QA 1N3AA 3KTUA
chains in the Genus database with same CATH superfamily
3OYLA 2H56A 4ZTJA 1NGNA 1PU6A 3N0UA 4NZGA 1YQLA 3IHOA 3FSPA 3S3NA 1RRQA 3OH6A 3S3OA 4UOBA 1KG5A 4BACA 3FHGA 1YQKA 5FRMA 4EA4A 1M3HA 1NKUA 3F0ZA 4E9FA 1MPGA 2JG6A 4YOQA 2XHIA 4BDYA 1YQRA 5CHZA 4E9GA 3S6IA 4E7JA 4B24A 1KG3A 1LWYA 1YQMA 3OS1A 3OYFA 1N39A 2ABKA 1P7MA 1PU8A 1ORPA 2YG8A 2NOBA 1KG2A 4E9EA 4EVVA 1KQJA 3I0XA 3L2RA 4AI5A 2JPSA 4OFEA 4BE1A 2OFKA 4OFAA 4B21A 3LCNA 4OFHA 3R2XC 1KEAA 2W03A 4B23A 1PU7A 4BDZA 1LWWA 1MUDA 2I5WA 4ZTFA 2V75A 4PIIA 4E7IA 2YG9A 3L2WA 1ORNA 4EJZA 3OYGA 2NOHA 1LWVA 3CVTA 3I0WA 3OYNA 3OYJA 1FN7A 3OYCA 1WEFA 4BE2A 3OH9A 2NOEA 1XG7A 1KG4A 5AN4A 3L2QA 4HSBA 3N5NX 3OYDA 5KN9A 3D4VA 3IH7A 1WEGA 1XQPA 3OY9A 3OYAA 1VRLA 4E7LA 3OYHA 3CVSA 3S3MA 1RRSA 3CW7A 4BE0A 2JHJA 1DIZA 1LMZA 4AIAA 3OGDA 4EA5A 1KG6A 4YPRA 3NNQA 3OYEA 3OYBA 3OS2A 1KO9A 2NOIA 1WEIA 2NOFA 2W04A 3L2VA 1P59A 5KN8A 4IKFA 3VW4A 5FROA 5FRNA 4UNFA 4B22A 1HU0A 3OS0A 2NOLA 1MUYA 4AI4A 3OYMA 4EW4A 4E7KA 3CWUA 5DPKA 1EBMA 3KNTA 4EJYA 1XQOA 4E7HA 3FHFA 2NOZA 4DK9A 1N3CA 1M3QA 4EW0A 1U84A 3L2UA 4YPHA 1KG7A 2JHNA 3CWSA 4E9HA 2OFIA 1MUNA 1PVSA 3OYIA 3CWAA 3OYKA 3CWTA 3F10A 3G0QA 1N3AA 3KTUA
chains in the Genus database with same CATH topology
2H56A 1NGNA 1PU6A 3N0UA 1YQLA 3IHOA 3FSPA 1RRQA 3OH6A 4UOBA 1KG5A 3FHGA 1YQKA 4EA4A 1M3HA 1NKUA 3F0ZA 4E9FA 1MPGA 2JG6A 4YOQA 2XHIA 1YQRA 5CHZA 4E9GA 3S6IA 4B24A 1KG3A 1LWYA 1YQMA 1N39A 2ABKA 1P7MA 1PU8A 1ORPA 2YG8A 2NOBA 1KG2A 4E9EA 4EVVA 1KQJA 3I0XA 4AI5A 4OFEA 2OFKA 4OFAA 4B21A 4OFHA 1KEAA 4B23A 1PU7A 1LWWA 2I5WA 1MUDA 4PIIA 2YG9A 1ORNA 4EJZA 2NOHA 1LWVA 3CVTA 3I0WA 1FN7A 1WEFA 3OH9A 2NOEA 1XG7A 1KG4A 5AN4A 4HSBA 3N5NX 5KN9A 3D4VA 3IH7A 1WEGA 1XQPA 1VRLA 3CVSA 1RRSA 3CW7A 2JHJA 1DIZA 1LMZA 4AIAA 3OGDA 4EA5A 1KG6A 4YPRA 1KO9A 2NOIA 1WEIA 2NOFA 1P59A 5KN8A 4UNFA 4B22A 1HU0A 2NOLA 1MUYA 4AI4A 4EW4A 3CWUA 5DPKA 1EBMA 3KNTA 4EJYA 1XQOA 3FHFA 2NOZA 4DK9A 1N3CA 1M3QA 4EW0A 4YPHA 1KG7A 2JHNA 3CWSA 4E9HA 2OFIA 1MUNA 1PVSA 3CWAA 3CWTA 3F10A 3G0QA 1N3AA 3KTUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H56 A;  1NGN A;  1PU6 A;  3N0U A;  1YQL A;  3IHO A;  3FSP A;  1RRQ A;  3OH6 A;  4UOB A;  1KG5 A;  3FHG A;  1YQK A;  4EA4 A;  1M3H A;  1NKU A;  3F0Z A;  4E9F A;  1MPG A;  2JG6 A;  4YOQ A;  2XHI A;  1YQR A;  5CHZ A;  4E9G A;  3S6I A;  4B24 A;  1KG3 A;  1LWY A;  1YQM A;  1N39 A;  2ABK A;  1P7M A;  1PU8 A;  1ORP A;  2YG8 A;  2NOB A;  1KG2 A;  4E9E A;  4EVV A;  1KQJ A;  3I0X A;  4AI5 A;  4OFE A;  2OFK A;  4OFA A;  4B21 A;  4OFH A;  1KEA A;  4B23 A;  1PU7 A;  1LWW A;  2I5W A;  1MUD A;  4PII A;  2YG9 A;  1ORN A;  4EJZ A;  2NOH A;  1LWV A;  3CVT A;  3I0W A;  1FN7 A;  1WEF A;  3OH9 A;  2NOE A;  1XG7 A;  1KG4 A;  5AN4 A;  4HSB A;  3N5N X;  5KN9 A;  3D4V A;  3IH7 A;  1WEG A;  1XQP A;  1VRL A;  3CVS A;  1RRS A;  3CW7 A;  2JHJ A;  1DIZ A;  1LMZ A;  4AIA A;  3OGD A;  4EA5 A;  1KG6 A;  4YPR A;  1KO9 A;  2NOI A;  1WEI A;  2NOF A;  1P59 A;  5KN8 A;  4UNF A;  4B22 A;  1HU0 A;  2NOL A;  1MUY A;  4AI4 A;  4EW4 A;  3CWU A;  5DPK A;  1EBM A;  3KNT A;  4EJY A;  1XQO A;  3FHF A;  2NOZ A;  4DK9 A;  1N3C A;  1M3Q A;  4EW0 A;  4YPH A;  1KG7 A;  2JHN A;  3CWS A;  4E9H A;  2OFI A;  1MUN A;  1PVS A;  3CWA A;  3CWT A;  3F10 A;  3G0Q A;  1N3A A;  3KTU A; 
#chains in the Genus database with same CATH topology
 3OYL A;  2H56 A;  4ZTJ A;  1NGN A;  1PU6 A;  3N0U A;  4NZG A;  1YQL A;  3IHO A;  3FSP A;  3S3N A;  1RRQ A;  3OH6 A;  3S3O A;  4UOB A;  1KG5 A;  4BAC A;  3FHG A;  1YQK A;  5FRM A;  4EA4 A;  1M3H A;  1NKU A;  3F0Z A;  4E9F A;  1MPG A;  2JG6 A;  4YOQ A;  2XHI A;  4BDY A;  1YQR A;  5CHZ A;  4E9G A;  3S6I A;  4E7J A;  4B24 A;  1KG3 A;  1LWY A;  1YQM A;  3OS1 A;  3OYF A;  1N39 A;  2ABK A;  1P7M A;  1PU8 A;  1ORP A;  2YG8 A;  2NOB A;  1KG2 A;  4E9E A;  4EVV A;  1KQJ A;  3I0X A;  3L2R A;  4AI5 A;  2JPS A;  4OFE A;  4BE1 A;  2OFK A;  4OFA A;  4B21 A;  3LCN A;  4OFH A;  3R2X C;  1KEA A;  2W03 A;  4B23 A;  1PU7 A;  4BDZ A;  1LWW A;  1MUD A;  2I5W A;  4ZTF A;  2V75 A;  4PII A;  4E7I A;  2YG9 A;  3L2W A;  1ORN A;  4EJZ A;  3OYG A;  2NOH A;  1LWV A;  3CVT A;  3I0W A;  3OYN A;  3OYJ A;  1FN7 A;  3OYC A;  1WEF A;  4BE2 A;  3OH9 A;  2NOE A;  1XG7 A;  1KG4 A;  5AN4 A;  3L2Q A;  4HSB A;  3N5N X;  3OYD A;  5KN9 A;  3D4V A;  3IH7 A;  1WEG A;  1XQP A;  3OY9 A;  3OYA A;  1VRL A;  4E7L A;  3OYH A;  3CVS A;  3S3M A;  1RRS A;  3CW7 A;  4BE0 A;  2JHJ A;  1DIZ A;  1LMZ A;  4AIA A;  3OGD A;  4EA5 A;  1KG6 A;  4YPR A;  3NNQ A;  3OYE A;  3OYB A;  3OS2 A;  1KO9 A;  2NOI A;  1WEI A;  2NOF A;  2W04 A;  3L2V A;  1P59 A;  5KN8 A;  4IKF A;  3VW4 A;  5FRO A;  5FRN A;  4UNF A;  4B22 A;  1HU0 A;  3OS0 A;  2NOL A;  1MUY A;  4AI4 A;  3OYM A;  4EW4 A;  4E7K A;  3CWU A;  5DPK A;  1EBM A;  3KNT A;  4EJY A;  1XQO A;  4E7H A;  3FHF A;  2NOZ A;  4DK9 A;  1N3C A;  1M3Q A;  4EW0 A;  1U84 A;  3L2U A;  4YPH A;  1KG7 A;  2JHN A;  3CWS A;  4E9H A;  2OFI A;  1MUN A;  1PVS A;  3OYI A;  3CWA A;  3OYK A;  3CWT A;  3F10 A;  3G0Q A;  1N3A A;  3KTU A; 
#chains in the Genus database with same CATH homology
 2H56 A;  1NGN A;  1PU6 A;  3N0U A;  1YQL A;  3IHO A;  3FSP A;  1RRQ A;  3OH6 A;  4UOB A;  1KG5 A;  3FHG A;  1YQK A;  4EA4 A;  1M3H A;  1NKU A;  3F0Z A;  4E9F A;  1MPG A;  2JG6 A;  4YOQ A;  2XHI A;  1YQR A;  5CHZ A;  4E9G A;  3S6I A;  4B24 A;  1KG3 A;  1LWY A;  1YQM A;  1N39 A;  2ABK A;  1P7M A;  1PU8 A;  1ORP A;  2YG8 A;  2NOB A;  1KG2 A;  4E9E A;  4EVV A;  1KQJ A;  3I0X A;  4AI5 A;  4OFE A;  2OFK A;  4OFA A;  4B21 A;  4OFH A;  1KEA A;  4B23 A;  1PU7 A;  1LWW A;  2I5W A;  1MUD A;  4PII A;  2YG9 A;  1ORN A;  4EJZ A;  2NOH A;  1LWV A;  3CVT A;  3I0W A;  1FN7 A;  1WEF A;  3OH9 A;  2NOE A;  1XG7 A;  1KG4 A;  5AN4 A;  4HSB A;  3N5N X;  5KN9 A;  3D4V A;  3IH7 A;  1WEG A;  1XQP A;  1VRL A;  3CVS A;  1RRS A;  3CW7 A;  2JHJ A;  1DIZ A;  1LMZ A;  4AIA A;  3OGD A;  4EA5 A;  1KG6 A;  4YPR A;  1KO9 A;  2NOI A;  1WEI A;  2NOF A;  1P59 A;  5KN8 A;  4UNF A;  4B22 A;  1HU0 A;  2NOL A;  1MUY A;  4AI4 A;  4EW4 A;  3CWU A;  5DPK A;  1EBM A;  3KNT A;  4EJY A;  1XQO A;  3FHF A;  2NOZ A;  4DK9 A;  1N3C A;  1M3Q A;  4EW0 A;  4YPH A;  1KG7 A;  2JHN A;  3CWS A;  4E9H A;  2OFI A;  1MUN A;  1PVS A;  3CWA A;  3CWT A;  3F10 A;  3G0Q A;  1N3A A;  3KTU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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