1WEFA

Catalytic domain of muty from escherichia coli k20a mutant
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRATLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords A/G-specific adenine glycosylase
total genus 71
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2004-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1wefA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1wefA01
2JG6A 3KNTA 5DPKA 4YPHA 5KN8A 4UNFA 4E9EA 4YPRA 3CWUA 1KG3A 3N0UA 4B24A 1LWWA 1KG5A 2OFKA 1RRQA 1N39A 4EVVA 1YQLA 1N3CA 2NOEA 4OFHA 4B22A 1KG6A 1FN7A 3OGDA 1MUYA 1MUNA 3FHGA 4AIAA 2YG9A 2JHNA 1LMZA 4B21A 2ABKA 1KEAA 2XHIA 2OFIA 4AI4A 4E9GA 1XG7A 1YQMA 1M3HA 1P59A 3F0ZA 3I0XA 1YQKA 4B23A 3FHFA 4OFAA 1ORNA 4EA4A 1WEIA 3I0WA 2NOFA 2NOLA 1PU6A 4EW4A 5KN9A 1KG4A 1DIZA 3CWSA 3CVTA 1KG7A 1MUDA 3CVSA 1LWVA 2YG8A 1XQOA 2NOBA 2I5WA 1EBMA 3FSPA 4DK9A 1KO9A 3D4VA 1LWYA 3G0QA 1XQPA 3N5NX 1KG2A 4EJYA 1N3AA 4EA5A 3CW7A 4HSBA 1VRLA 1NKUA 4OFEA 2NOZA 2JHJA 2H56A 4AI5A 4PIIA 1PU8A 4E9HA 3OH6A 3CWTA 1ORPA 1NGNA 1PVSA 3F10A 1MPGA 1P7MA 1WEGA 1KQJA 4EJZA 1PU7A 1RRSA 4EW0A 5AN4A 5CHZA 4E9FA 4YOQA 4UOBA 3CWAA 3S6IA 1WEFA 1M3QA 3KTUA 3OH9A 3IHOA 3IH7A 1HU0A 2NOHA 2NOIA 1YQRA
chains in the Genus database with same CATH superfamily
2JG6A 3KNTA 5DPKA 4YPHA 3OYNA 5KN8A 5FRMA 4UNFA 4E9EA 4YPRA 3OYEA 1KG3A 3N0UA 3R2XC 3CWUA 3OS0A 3L2UA 4E7KA 4E7LA 4B24A 1LWWA 1KG5A 2OFKA 4BDZA 1RRQA 4NZGA 1N39A 5FRNA 4BACA 4EVVA 1U84A 3S3OA 1YQLA 1N3CA 2NOEA 4OFHA 4B22A 1KG6A 3VW4A 1FN7A 3OS2A 3OGDA 1MUYA 1MUNA 3FHGA 4AIAA 4BE1A 2YG9A 3OYLA 2JHNA 1LMZA 3OYFA 4B21A 4BE2A 3OYMA 3OYAA 2ABKA 1KEAA 2XHIA 4ZTFA 2OFIA 4AI4A 4E9GA 1XG7A 1YQMA 1M3HA 1P59A 3F0ZA 3I0XA 1YQKA 4B23A 3OYJA 3FHFA 4OFAA 3L2WA 3OYIA 1ORNA 4EA4A 4ZTJA 1WEIA 3OYGA 3I0WA 2NOFA 2NOLA 1PU6A 4EW4A 5KN9A 1KG4A 1DIZA 4E7IA 3CWSA 3CVTA 1KG7A 1MUDA 3CVSA 1LWVA 2YG8A 1XQOA 2NOBA 2I5WA 1EBMA 3OYHA 3FSPA 4DK9A 1KO9A 4BE0A 2JPSA 3D4VA 2V75A 3OYCA 2W03A 1LWYA 3G0QA 1XQPA 3N5NX 1KG2A 4E7JA 4EJYA 1N3AA 4EA5A 3OYBA 3CW7A 4HSBA 1VRLA 1NKUA 4OFEA 4IKFA 2NOZA 2JHJA 2W04A 2H56A 3L2VA 4PIIA 4AI5A 1PU8A 4E9HA 3OH6A 3CWTA 3LCNA 5FROA 1ORPA 1NGNA 1PVSA 3F10A 1MPGA 1P7MA 1WEGA 1KQJA 3S3NA 4EJZA 4E7HA 3L2RA 1PU7A 1RRSA 4EW0A 3L2QA 5AN4A 5CHZA 4E9FA 4YOQA 4UOBA 3CWAA 3S6IA 3S3MA 1WEFA 1M3QA 3OYKA 3KTUA 3OYDA 3OH9A 3IHOA 4BDYA 3IH7A 1HU0A 3OY9A 2NOHA 3NNQA 2NOIA 3OS1A 1YQRA
chains in the Genus database with same CATH topology
2JG6A 3KNTA 5DPKA 4YPHA 5KN8A 4UNFA 4E9EA 4YPRA 3CWUA 1KG3A 3N0UA 4B24A 1LWWA 1KG5A 2OFKA 1RRQA 1N39A 4EVVA 1YQLA 1N3CA 2NOEA 4OFHA 4B22A 1KG6A 1FN7A 3OGDA 1MUYA 1MUNA 3FHGA 4AIAA 2YG9A 2JHNA 1LMZA 4B21A 2ABKA 1KEAA 2XHIA 2OFIA 4AI4A 4E9GA 1XG7A 1YQMA 1M3HA 1P59A 3F0ZA 3I0XA 1YQKA 4B23A 3FHFA 4OFAA 1ORNA 4EA4A 1WEIA 3I0WA 2NOFA 2NOLA 1PU6A 4EW4A 5KN9A 1KG4A 1DIZA 3CWSA 3CVTA 1KG7A 1MUDA 3CVSA 1LWVA 2YG8A 1XQOA 2NOBA 2I5WA 1EBMA 3FSPA 4DK9A 1KO9A 3D4VA 1LWYA 3G0QA 1XQPA 3N5NX 1KG2A 4EJYA 1N3AA 4EA5A 3CW7A 4HSBA 1VRLA 1NKUA 4OFEA 2NOZA 2JHJA 2H56A 4AI5A 4PIIA 1PU8A 4E9HA 3OH6A 3CWTA 1ORPA 1NGNA 1PVSA 3F10A 1MPGA 1P7MA 1WEGA 1KQJA 4EJZA 1PU7A 1RRSA 4EW0A 5AN4A 5CHZA 4E9FA 4YOQA 4UOBA 3CWAA 3S6IA 1WEFA 1M3QA 3KTUA 3OH9A 3IHOA 3IH7A 1HU0A 2NOHA 2NOIA 1YQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JG6 A;  3KNT A;  5DPK A;  4YPH A;  5KN8 A;  4UNF A;  4E9E A;  4YPR A;  3CWU A;  1KG3 A;  3N0U A;  4B24 A;  1LWW A;  1KG5 A;  2OFK A;  1RRQ A;  1N39 A;  4EVV A;  1YQL A;  1N3C A;  2NOE A;  4OFH A;  4B22 A;  1KG6 A;  1FN7 A;  3OGD A;  1MUY A;  1MUN A;  3FHG A;  4AIA A;  2YG9 A;  2JHN A;  1LMZ A;  4B21 A;  2ABK A;  1KEA A;  2XHI A;  2OFI A;  4AI4 A;  4E9G A;  1XG7 A;  1YQM A;  1M3H A;  1P59 A;  3F0Z A;  3I0X A;  1YQK A;  4B23 A;  3FHF A;  4OFA A;  1ORN A;  4EA4 A;  1WEI A;  3I0W A;  2NOF A;  2NOL A;  1PU6 A;  4EW4 A;  5KN9 A;  1KG4 A;  1DIZ A;  3CWS A;  3CVT A;  1KG7 A;  1MUD A;  3CVS A;  1LWV A;  2YG8 A;  1XQO A;  2NOB A;  2I5W A;  1EBM A;  3FSP A;  4DK9 A;  1KO9 A;  3D4V A;  1LWY A;  3G0Q A;  1XQP A;  3N5N X;  1KG2 A;  4EJY A;  1N3A A;  4EA5 A;  3CW7 A;  4HSB A;  1VRL A;  1NKU A;  4OFE A;  2NOZ A;  2JHJ A;  2H56 A;  4AI5 A;  4PII A;  1PU8 A;  4E9H A;  3OH6 A;  3CWT A;  1ORP A;  1NGN A;  1PVS A;  3F10 A;  1MPG A;  1P7M A;  1WEG A;  1KQJ A;  4EJZ A;  1PU7 A;  1RRS A;  4EW0 A;  5AN4 A;  5CHZ A;  4E9F A;  4YOQ A;  4UOB A;  3CWA A;  3S6I A;  1WEF A;  1M3Q A;  3KTU A;  3OH9 A;  3IHO A;  3IH7 A;  1HU0 A;  2NOH A;  2NOI A;  1YQR A; 
#chains in the Genus database with same CATH topology
 2JG6 A;  3KNT A;  5DPK A;  4YPH A;  3OYN A;  5KN8 A;  5FRM A;  4UNF A;  4E9E A;  4YPR A;  3OYE A;  1KG3 A;  3N0U A;  3R2X C;  3CWU A;  3OS0 A;  3L2U A;  4E7K A;  4E7L A;  4B24 A;  1LWW A;  1KG5 A;  2OFK A;  4BDZ A;  1RRQ A;  4NZG A;  1N39 A;  5FRN A;  4BAC A;  4EVV A;  1U84 A;  3S3O A;  1YQL A;  1N3C A;  2NOE A;  4OFH A;  4B22 A;  1KG6 A;  3VW4 A;  1FN7 A;  3OS2 A;  3OGD A;  1MUY A;  1MUN A;  3FHG A;  4AIA A;  4BE1 A;  2YG9 A;  3OYL A;  2JHN A;  1LMZ A;  3OYF A;  4B21 A;  4BE2 A;  3OYM A;  3OYA A;  2ABK A;  1KEA A;  2XHI A;  4ZTF A;  2OFI A;  4AI4 A;  4E9G A;  1XG7 A;  1YQM A;  1M3H A;  1P59 A;  3F0Z A;  3I0X A;  1YQK A;  4B23 A;  3OYJ A;  3FHF A;  4OFA A;  3L2W A;  3OYI A;  1ORN A;  4EA4 A;  4ZTJ A;  1WEI A;  3OYG A;  3I0W A;  2NOF A;  2NOL A;  1PU6 A;  4EW4 A;  5KN9 A;  1KG4 A;  1DIZ A;  4E7I A;  3CWS A;  3CVT A;  1KG7 A;  1MUD A;  3CVS A;  1LWV A;  2YG8 A;  1XQO A;  2NOB A;  2I5W A;  1EBM A;  3OYH A;  3FSP A;  4DK9 A;  1KO9 A;  4BE0 A;  2JPS A;  3D4V A;  2V75 A;  3OYC A;  2W03 A;  1LWY A;  3G0Q A;  1XQP A;  3N5N X;  1KG2 A;  4E7J A;  4EJY A;  1N3A A;  4EA5 A;  3OYB A;  3CW7 A;  4HSB A;  1VRL A;  1NKU A;  4OFE A;  4IKF A;  2NOZ A;  2JHJ A;  2W04 A;  2H56 A;  3L2V A;  4PII A;  4AI5 A;  1PU8 A;  4E9H A;  3OH6 A;  3CWT A;  3LCN A;  5FRO A;  1ORP A;  1NGN A;  1PVS A;  3F10 A;  1MPG A;  1P7M A;  1WEG A;  1KQJ A;  3S3N A;  4EJZ A;  4E7H A;  3L2R A;  1PU7 A;  1RRS A;  4EW0 A;  3L2Q A;  5AN4 A;  5CHZ A;  4E9F A;  4YOQ A;  4UOB A;  3CWA A;  3S6I A;  3S3M A;  1WEF A;  1M3Q A;  3OYK A;  3KTU A;  3OYD A;  3OH9 A;  3IHO A;  4BDY A;  3IH7 A;  1HU0 A;  3OY9 A;  2NOH A;  3NNQ A;  2NOI A;  3OS1 A;  1YQR A; 
#chains in the Genus database with same CATH homology
 2JG6 A;  3KNT A;  5DPK A;  4YPH A;  5KN8 A;  4UNF A;  4E9E A;  4YPR A;  3CWU A;  1KG3 A;  3N0U A;  4B24 A;  1LWW A;  1KG5 A;  2OFK A;  1RRQ A;  1N39 A;  4EVV A;  1YQL A;  1N3C A;  2NOE A;  4OFH A;  4B22 A;  1KG6 A;  1FN7 A;  3OGD A;  1MUY A;  1MUN A;  3FHG A;  4AIA A;  2YG9 A;  2JHN A;  1LMZ A;  4B21 A;  2ABK A;  1KEA A;  2XHI A;  2OFI A;  4AI4 A;  4E9G A;  1XG7 A;  1YQM A;  1M3H A;  1P59 A;  3F0Z A;  3I0X A;  1YQK A;  4B23 A;  3FHF A;  4OFA A;  1ORN A;  4EA4 A;  1WEI A;  3I0W A;  2NOF A;  2NOL A;  1PU6 A;  4EW4 A;  5KN9 A;  1KG4 A;  1DIZ A;  3CWS A;  3CVT A;  1KG7 A;  1MUD A;  3CVS A;  1LWV A;  2YG8 A;  1XQO A;  2NOB A;  2I5W A;  1EBM A;  3FSP A;  4DK9 A;  1KO9 A;  3D4V A;  1LWY A;  3G0Q A;  1XQP A;  3N5N X;  1KG2 A;  4EJY A;  1N3A A;  4EA5 A;  3CW7 A;  4HSB A;  1VRL A;  1NKU A;  4OFE A;  2NOZ A;  2JHJ A;  2H56 A;  4AI5 A;  4PII A;  1PU8 A;  4E9H A;  3OH6 A;  3CWT A;  1ORP A;  1NGN A;  1PVS A;  3F10 A;  1MPG A;  1P7M A;  1WEG A;  1KQJ A;  4EJZ A;  1PU7 A;  1RRS A;  4EW0 A;  5AN4 A;  5CHZ A;  4E9F A;  4YOQ A;  4UOB A;  3CWA A;  3S6I A;  1WEF A;  1M3Q A;  3KTU A;  3OH9 A;  3IHO A;  3IH7 A;  1HU0 A;  2NOH A;  2NOI A;  1YQR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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