The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
71
|
sequence length |
225
|
structure length |
225
|
Chain Sequence |
MQASQFSAQVLDWYDKYGRATLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb |
molecule tags |
Hydrolase
|
source organism |
Escherichia coli
|
molecule keywords |
A/G-specific adenine glycosylase
|
total genus |
71
|
structure length |
225
|
sequence length |
225
|
ec nomenclature |
ec
3.2.2.31: Adenine glycosylase. |
pdb deposition date | 2004-05-25 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
A | PF00633 | HHH | Helix-hairpin-helix motif |
A | PF00730 | HhH-GPD | HhH-GPD superfamily base excision DNA repair protein |
A | PF10576 | EndIII_4Fe-2S | Iron-sulfur binding domain of endonuclease III |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Mainly Alpha | Orthogonal Bundle | Endonuclease III; domain 1 | Hypothetical protein; domain 2 | ||
Mainly Alpha | Orthogonal Bundle | Endonuclease Iii, domain 2 | Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) |
#chains in the Genus database with same CATH superfamily 2JG6 A; 3KNT A; 5DPK A; 4YPH A; 5KN8 A; 4UNF A; 4E9E A; 4YPR A; 3CWU A; 1KG3 A; 3N0U A; 4B24 A; 1LWW A; 1KG5 A; 2OFK A; 1RRQ A; 1N39 A; 4EVV A; 1YQL A; 1N3C A; 2NOE A; 4OFH A; 4B22 A; 1KG6 A; 1FN7 A; 3OGD A; 1MUY A; 1MUN A; 3FHG A; 4AIA A; 2YG9 A; 2JHN A; 1LMZ A; 4B21 A; 2ABK A; 1KEA A; 2XHI A; 2OFI A; 4AI4 A; 4E9G A; 1XG7 A; 1YQM A; 1M3H A; 1P59 A; 3F0Z A; 3I0X A; 1YQK A; 4B23 A; 3FHF A; 4OFA A; 1ORN A; 4EA4 A; 1WEI A; 3I0W A; 2NOF A; 2NOL A; 1PU6 A; 4EW4 A; 5KN9 A; 1KG4 A; 1DIZ A; 3CWS A; 3CVT A; 1KG7 A; 1MUD A; 3CVS A; 1LWV A; 2YG8 A; 1XQO A; 2NOB A; 2I5W A; 1EBM A; 3FSP A; 4DK9 A; 1KO9 A; 3D4V A; 1LWY A; 3G0Q A; 1XQP A; 3N5N X; 1KG2 A; 4EJY A; 1N3A A; 4EA5 A; 3CW7 A; 4HSB A; 1VRL A; 1NKU A; 4OFE A; 2NOZ A; 2JHJ A; 2H56 A; 4AI5 A; 4PII A; 1PU8 A; 4E9H A; 3OH6 A; 3CWT A; 1ORP A; 1NGN A; 1PVS A; 3F10 A; 1MPG A; 1P7M A; 1WEG A; 1KQJ A; 4EJZ A; 1PU7 A; 1RRS A; 4EW0 A; 5AN4 A; 5CHZ A; 4E9F A; 4YOQ A; 4UOB A; 3CWA A; 3S6I A; 1WEF A; 1M3Q A; 3KTU A; 3OH9 A; 3IHO A; 3IH7 A; 1HU0 A; 2NOH A; 2NOI A; 1YQR A; #chains in the Genus database with same CATH topology 2JG6 A; 3KNT A; 5DPK A; 4YPH A; 3OYN A; 5KN8 A; 5FRM A; 4UNF A; 4E9E A; 4YPR A; 3OYE A; 1KG3 A; 3N0U A; 3R2X C; 3CWU A; 3OS0 A; 3L2U A; 4E7K A; 4E7L A; 4B24 A; 1LWW A; 1KG5 A; 2OFK A; 4BDZ A; 1RRQ A; 4NZG A; 1N39 A; 5FRN A; 4BAC A; 4EVV A; 1U84 A; 3S3O A; 1YQL A; 1N3C A; 2NOE A; 4OFH A; 4B22 A; 1KG6 A; 3VW4 A; 1FN7 A; 3OS2 A; 3OGD A; 1MUY A; 1MUN A; 3FHG A; 4AIA A; 4BE1 A; 2YG9 A; 3OYL A; 2JHN A; 1LMZ A; 3OYF A; 4B21 A; 4BE2 A; 3OYM A; 3OYA A; 2ABK A; 1KEA A; 2XHI A; 4ZTF A; 2OFI A; 4AI4 A; 4E9G A; 1XG7 A; 1YQM A; 1M3H A; 1P59 A; 3F0Z A; 3I0X A; 1YQK A; 4B23 A; 3OYJ A; 3FHF A; 4OFA A; 3L2W A; 3OYI A; 1ORN A; 4EA4 A; 4ZTJ A; 1WEI A; 3OYG A; 3I0W A; 2NOF A; 2NOL A; 1PU6 A; 4EW4 A; 5KN9 A; 1KG4 A; 1DIZ A; 4E7I A; 3CWS A; 3CVT A; 1KG7 A; 1MUD A; 3CVS A; 1LWV A; 2YG8 A; 1XQO A; 2NOB A; 2I5W A; 1EBM A; 3OYH A; 3FSP A; 4DK9 A; 1KO9 A; 4BE0 A; 2JPS A; 3D4V A; 2V75 A; 3OYC A; 2W03 A; 1LWY A; 3G0Q A; 1XQP A; 3N5N X; 1KG2 A; 4E7J A; 4EJY A; 1N3A A; 4EA5 A; 3OYB A; 3CW7 A; 4HSB A; 1VRL A; 1NKU A; 4OFE A; 4IKF A; 2NOZ A; 2JHJ A; 2W04 A; 2H56 A; 3L2V A; 4PII A; 4AI5 A; 1PU8 A; 4E9H A; 3OH6 A; 3CWT A; 3LCN A; 5FRO A; 1ORP A; 1NGN A; 1PVS A; 3F10 A; 1MPG A; 1P7M A; 1WEG A; 1KQJ A; 3S3N A; 4EJZ A; 4E7H A; 3L2R A; 1PU7 A; 1RRS A; 4EW0 A; 3L2Q A; 5AN4 A; 5CHZ A; 4E9F A; 4YOQ A; 4UOB A; 3CWA A; 3S6I A; 3S3M A; 1WEF A; 1M3Q A; 3OYK A; 3KTU A; 3OYD A; 3OH9 A; 3IHO A; 4BDY A; 3IH7 A; 1HU0 A; 3OY9 A; 2NOH A; 3NNQ A; 2NOI A; 3OS1 A; 1YQR A; #chains in the Genus database with same CATH homology 2JG6 A; 3KNT A; 5DPK A; 4YPH A; 5KN8 A; 4UNF A; 4E9E A; 4YPR A; 3CWU A; 1KG3 A; 3N0U A; 4B24 A; 1LWW A; 1KG5 A; 2OFK A; 1RRQ A; 1N39 A; 4EVV A; 1YQL A; 1N3C A; 2NOE A; 4OFH A; 4B22 A; 1KG6 A; 1FN7 A; 3OGD A; 1MUY A; 1MUN A; 3FHG A; 4AIA A; 2YG9 A; 2JHN A; 1LMZ A; 4B21 A; 2ABK A; 1KEA A; 2XHI A; 2OFI A; 4AI4 A; 4E9G A; 1XG7 A; 1YQM A; 1M3H A; 1P59 A; 3F0Z A; 3I0X A; 1YQK A; 4B23 A; 3FHF A; 4OFA A; 1ORN A; 4EA4 A; 1WEI A; 3I0W A; 2NOF A; 2NOL A; 1PU6 A; 4EW4 A; 5KN9 A; 1KG4 A; 1DIZ A; 3CWS A; 3CVT A; 1KG7 A; 1MUD A; 3CVS A; 1LWV A; 2YG8 A; 1XQO A; 2NOB A; 2I5W A; 1EBM A; 3FSP A; 4DK9 A; 1KO9 A; 3D4V A; 1LWY A; 3G0Q A; 1XQP A; 3N5N X; 1KG2 A; 4EJY A; 1N3A A; 4EA5 A; 3CW7 A; 4HSB A; 1VRL A; 1NKU A; 4OFE A; 2NOZ A; 2JHJ A; 2H56 A; 4AI5 A; 4PII A; 1PU8 A; 4E9H A; 3OH6 A; 3CWT A; 1ORP A; 1NGN A; 1PVS A; 3F10 A; 1MPG A; 1P7M A; 1WEG A; 1KQJ A; 4EJZ A; 1PU7 A; 1RRS A; 4EW0 A; 5AN4 A; 5CHZ A; 4E9F A; 4YOQ A; 4UOB A; 3CWA A; 3S6I A; 1WEF A; 1M3Q A; 3KTU A; 3OH9 A; 3IHO A; 3IH7 A; 1HU0 A; 2NOH A; 2NOI A; 1YQR A;
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