1WEIA

Catalytic domain of muty from escherichia coli k20a mutant complexed to adenine
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
224
structure length
220
Chain Sequence
MQASQFSAQVLDWYDKYGRATLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARYAVSGWPGKKEVENKLWLSEQVTPAVGVERFNQAMMDLGAMCTRSKPKCLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords A/G-specific adenine glycosylase
total genus 68
structure length 220
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2004-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1weiA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1weiA01
1WEGA 1KQJA 4DK9A 1N39A 2I5WA 4EW4A 1YQKA 3N0UA 1RRSA 2NOLA 1FN7A 1ORNA 4EW0A 1LWVA 1MPGA 1XQPA 1RRQA 1N3CA 2ABKA 4AIAA 1MUNA 4B22A 1MUYA 3CWAA 2YG9A 2XHIA 1KO9A 3FHGA 1KG3A 4YPHA 1P7MA 2H56A 3FSPA 1WEIA 2OFIA 3S6IA 2YG8A 3IHOA 5KN8A 4OFAA 1P59A 2NOBA 4EA4A 1MUDA 3I0XA 3D4VA 2OFKA 1KG6A 4EVVA 1M3HA 4OFEA 3KTUA 4EJYA 4AI5A 1HU0A 4E9GA 3CWSA 1M3QA 1LWYA 3G0QA 1ORPA 4EJZA 1YQLA 2NOZA 3F10A 4E9EA 1XQOA 4B23A 3CWTA 4EA5A 4UOBA 1PU8A 1YQMA 3CWUA 3CVSA 2NOEA 3OH9A 2NOIA 4HSBA 5KN9A 3KNTA 1N3AA 5AN4A 1YQRA 2NOFA 4B21A 4YOQA 1KG2A 3F0ZA 4OFHA 3I0WA 2NOHA 1KG7A 2JG6A 3CW7A 1KG5A 1LWWA 4UNFA 3OGDA 4PIIA 1LMZA 3OH6A 5DPKA 1DIZA 1VRLA 2JHJA 1NGNA 1KG4A 1EBMA 1KEAA 4E9FA 2JHNA 1PU7A 4E9HA 1XG7A 3CVTA 1NKUA 1PU6A 1WEFA 3FHFA 4B24A 3N5NX 3IH7A 4YPRA 5CHZA 1PVSA 4AI4A
chains in the Genus database with same CATH superfamily
1WEGA 1KQJA 4DK9A 1N39A 2I5WA 4EW4A 1YQKA 3N0UA 2JPSA 1RRSA 1FN7A 2NOLA 1ORNA 3NNQA 4EW0A 1LWVA 1MPGA 4E7HA 1XQPA 3S3MA 4BE2A 1RRQA 3OYKA 1N3CA 2ABKA 4AIAA 3OYFA 1MUNA 4B22A 1MUYA 3CWAA 3VW4A 2YG9A 2XHIA 1KO9A 3FHGA 3OYBA 1KG3A 4YPHA 1P7MA 2H56A 3FSPA 1WEIA 2OFIA 3S6IA 2YG8A 3OYGA 3IHOA 4BE0A 4ZTJA 5KN8A 2W03A 4NZGA 4BDZA 4OFAA 1P59A 2NOBA 4EA4A 1MUDA 3I0XA 3D4VA 2OFKA 1KG6A 3OYJA 4EVVA 1M3HA 4IKFA 4OFEA 3R2XC 3KTUA 3L2UA 3S3NA 4EJYA 4AI5A 5FRMA 1HU0A 4E9GA 3CWSA 1M3QA 1LWYA 2W04A 3G0QA 1ORPA 4EJZA 1YQLA 3OYIA 2NOZA 3F10A 4E9EA 1XQOA 3OYHA 4B23A 3CWTA 5FROA 4EA5A 4UOBA 1PU8A 1YQMA 3L2QA 4ZTFA 3CWUA 3CVSA 2NOEA 3OH9A 2NOIA 3OYCA 4HSBA 5KN9A 3KNTA 1N3AA 5AN4A 1YQRA 2NOFA 2V75A 4B21A 4YOQA 1KG2A 3F0ZA 3L2WA 4OFHA 1U84A 3I0WA 4E7LA 3OYLA 2NOHA 3OS2A 3L2VA 1KG7A 4E7KA 2JG6A 3OYMA 3OYAA 3CW7A 1KG5A 1LWWA 4UNFA 3OGDA 4PIIA 1LMZA 3S3OA 3OYNA 3OH6A 5DPKA 1DIZA 3OYDA 1VRLA 2JHJA 4E7IA 1NGNA 1KG4A 3OS1A 1EBMA 4E7JA 3OYEA 4BE1A 1KEAA 4BACA 2JHNA 1PU7A 4E9HA 1XG7A 4E9FA 3CVTA 1NKUA 1PU6A 1WEFA 3FHFA 3OY9A 3OS0A 3N5NX 4B24A 3IH7A 5FRNA 4YPRA 3LCNA 5CHZA 1PVSA 4AI4A 3L2RA 4BDYA
chains in the Genus database with same CATH topology
1WEGA 1KQJA 4DK9A 1N39A 2I5WA 4EW4A 1YQKA 3N0UA 1RRSA 2NOLA 1FN7A 1ORNA 4EW0A 1LWVA 1MPGA 1XQPA 1RRQA 1N3CA 2ABKA 4AIAA 1MUNA 4B22A 1MUYA 3CWAA 2YG9A 2XHIA 1KO9A 3FHGA 1KG3A 4YPHA 1P7MA 2H56A 3FSPA 1WEIA 2OFIA 3S6IA 2YG8A 3IHOA 5KN8A 4OFAA 1P59A 2NOBA 4EA4A 1MUDA 3I0XA 3D4VA 2OFKA 1KG6A 4EVVA 1M3HA 4OFEA 3KTUA 4EJYA 4AI5A 1HU0A 4E9GA 3CWSA 1M3QA 1LWYA 3G0QA 1ORPA 4EJZA 1YQLA 2NOZA 3F10A 4E9EA 1XQOA 4B23A 3CWTA 4EA5A 4UOBA 1PU8A 1YQMA 3CWUA 3CVSA 2NOEA 3OH9A 2NOIA 4HSBA 5KN9A 3KNTA 1N3AA 5AN4A 1YQRA 2NOFA 4B21A 4YOQA 1KG2A 3F0ZA 4OFHA 3I0WA 2NOHA 1KG7A 2JG6A 3CW7A 1KG5A 1LWWA 4UNFA 3OGDA 4PIIA 1LMZA 3OH6A 5DPKA 1DIZA 1VRLA 2JHJA 1NGNA 1KG4A 1EBMA 1KEAA 4E9FA 2JHNA 1PU7A 4E9HA 1XG7A 3CVTA 1NKUA 1PU6A 1WEFA 3FHFA 4B24A 3N5NX 3IH7A 4YPRA 5CHZA 1PVSA 4AI4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WEG A;  1KQJ A;  4DK9 A;  1N39 A;  2I5W A;  4EW4 A;  1YQK A;  3N0U A;  1RRS A;  2NOL A;  1FN7 A;  1ORN A;  4EW0 A;  1LWV A;  1MPG A;  1XQP A;  1RRQ A;  1N3C A;  2ABK A;  4AIA A;  1MUN A;  4B22 A;  1MUY A;  3CWA A;  2YG9 A;  2XHI A;  1KO9 A;  3FHG A;  1KG3 A;  4YPH A;  1P7M A;  2H56 A;  3FSP A;  1WEI A;  2OFI A;  3S6I A;  2YG8 A;  3IHO A;  5KN8 A;  4OFA A;  1P59 A;  2NOB A;  4EA4 A;  1MUD A;  3I0X A;  3D4V A;  2OFK A;  1KG6 A;  4EVV A;  1M3H A;  4OFE A;  3KTU A;  4EJY A;  4AI5 A;  1HU0 A;  4E9G A;  3CWS A;  1M3Q A;  1LWY A;  3G0Q A;  1ORP A;  4EJZ A;  1YQL A;  2NOZ A;  3F10 A;  4E9E A;  1XQO A;  4B23 A;  3CWT A;  4EA5 A;  4UOB A;  1PU8 A;  1YQM A;  3CWU A;  3CVS A;  2NOE A;  3OH9 A;  2NOI A;  4HSB A;  5KN9 A;  3KNT A;  1N3A A;  5AN4 A;  1YQR A;  2NOF A;  4B21 A;  4YOQ A;  1KG2 A;  3F0Z A;  4OFH A;  3I0W A;  2NOH A;  1KG7 A;  2JG6 A;  3CW7 A;  1KG5 A;  1LWW A;  4UNF A;  3OGD A;  4PII A;  1LMZ A;  3OH6 A;  5DPK A;  1DIZ A;  1VRL A;  2JHJ A;  1NGN A;  1KG4 A;  1EBM A;  1KEA A;  4E9F A;  2JHN A;  1PU7 A;  4E9H A;  1XG7 A;  3CVT A;  1NKU A;  1PU6 A;  1WEF A;  3FHF A;  4B24 A;  3N5N X;  3IH7 A;  4YPR A;  5CHZ A;  1PVS A;  4AI4 A; 
#chains in the Genus database with same CATH topology
 1WEG A;  1KQJ A;  4DK9 A;  1N39 A;  2I5W A;  4EW4 A;  1YQK A;  3N0U A;  2JPS A;  1RRS A;  1FN7 A;  2NOL A;  1ORN A;  3NNQ A;  4EW0 A;  1LWV A;  1MPG A;  4E7H A;  1XQP A;  3S3M A;  4BE2 A;  1RRQ A;  3OYK A;  1N3C A;  2ABK A;  4AIA A;  3OYF A;  1MUN A;  4B22 A;  1MUY A;  3CWA A;  3VW4 A;  2YG9 A;  2XHI A;  1KO9 A;  3FHG A;  3OYB A;  1KG3 A;  4YPH A;  1P7M A;  2H56 A;  3FSP A;  1WEI A;  2OFI A;  3S6I A;  2YG8 A;  3OYG A;  3IHO A;  4BE0 A;  4ZTJ A;  5KN8 A;  2W03 A;  4NZG A;  4BDZ A;  4OFA A;  1P59 A;  2NOB A;  4EA4 A;  1MUD A;  3I0X A;  3D4V A;  2OFK A;  1KG6 A;  3OYJ A;  4EVV A;  1M3H A;  4IKF A;  4OFE A;  3R2X C;  3KTU A;  3L2U A;  3S3N A;  4EJY A;  4AI5 A;  5FRM A;  1HU0 A;  4E9G A;  3CWS A;  1M3Q A;  1LWY A;  2W04 A;  3G0Q A;  1ORP A;  4EJZ A;  1YQL A;  3OYI A;  2NOZ A;  3F10 A;  4E9E A;  1XQO A;  3OYH A;  4B23 A;  3CWT A;  5FRO A;  4EA5 A;  4UOB A;  1PU8 A;  1YQM A;  3L2Q A;  4ZTF A;  3CWU A;  3CVS A;  2NOE A;  3OH9 A;  2NOI A;  3OYC A;  4HSB A;  5KN9 A;  3KNT A;  1N3A A;  5AN4 A;  1YQR A;  2NOF A;  2V75 A;  4B21 A;  4YOQ A;  1KG2 A;  3F0Z A;  3L2W A;  4OFH A;  1U84 A;  3I0W A;  4E7L A;  3OYL A;  2NOH A;  3OS2 A;  3L2V A;  1KG7 A;  4E7K A;  2JG6 A;  3OYM A;  3OYA A;  3CW7 A;  1KG5 A;  1LWW A;  4UNF A;  3OGD A;  4PII A;  1LMZ A;  3S3O A;  3OYN A;  3OH6 A;  5DPK A;  1DIZ A;  3OYD A;  1VRL A;  2JHJ A;  4E7I A;  1NGN A;  1KG4 A;  3OS1 A;  1EBM A;  4E7J A;  3OYE A;  4BE1 A;  1KEA A;  4BAC A;  2JHN A;  1PU7 A;  4E9H A;  1XG7 A;  4E9F A;  3CVT A;  1NKU A;  1PU6 A;  1WEF A;  3FHF A;  3OY9 A;  3OS0 A;  3N5N X;  4B24 A;  3IH7 A;  5FRN A;  4YPR A;  3LCN A;  5CHZ A;  1PVS A;  4AI4 A;  3L2R A;  4BDY A; 
#chains in the Genus database with same CATH homology
 1WEG A;  1KQJ A;  4DK9 A;  1N39 A;  2I5W A;  4EW4 A;  1YQK A;  3N0U A;  1RRS A;  2NOL A;  1FN7 A;  1ORN A;  4EW0 A;  1LWV A;  1MPG A;  1XQP A;  1RRQ A;  1N3C A;  2ABK A;  4AIA A;  1MUN A;  4B22 A;  1MUY A;  3CWA A;  2YG9 A;  2XHI A;  1KO9 A;  3FHG A;  1KG3 A;  4YPH A;  1P7M A;  2H56 A;  3FSP A;  1WEI A;  2OFI A;  3S6I A;  2YG8 A;  3IHO A;  5KN8 A;  4OFA A;  1P59 A;  2NOB A;  4EA4 A;  1MUD A;  3I0X A;  3D4V A;  2OFK A;  1KG6 A;  4EVV A;  1M3H A;  4OFE A;  3KTU A;  4EJY A;  4AI5 A;  1HU0 A;  4E9G A;  3CWS A;  1M3Q A;  1LWY A;  3G0Q A;  1ORP A;  4EJZ A;  1YQL A;  2NOZ A;  3F10 A;  4E9E A;  1XQO A;  4B23 A;  3CWT A;  4EA5 A;  4UOB A;  1PU8 A;  1YQM A;  3CWU A;  3CVS A;  2NOE A;  3OH9 A;  2NOI A;  4HSB A;  5KN9 A;  3KNT A;  1N3A A;  5AN4 A;  1YQR A;  2NOF A;  4B21 A;  4YOQ A;  1KG2 A;  3F0Z A;  4OFH A;  3I0W A;  2NOH A;  1KG7 A;  2JG6 A;  3CW7 A;  1KG5 A;  1LWW A;  4UNF A;  3OGD A;  4PII A;  1LMZ A;  3OH6 A;  5DPK A;  1DIZ A;  1VRL A;  2JHJ A;  1NGN A;  1KG4 A;  1EBM A;  1KEA A;  4E9F A;  2JHN A;  1PU7 A;  4E9H A;  1XG7 A;  3CVT A;  1NKU A;  1PU6 A;  1WEF A;  3FHF A;  4B24 A;  3N5N X;  3IH7 A;  4YPR A;  5CHZ A;  1PVS A;  4AI4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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