1E78A

Crystal structure of human serum albumin
Total Genus 204
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
204
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Binding of the General Anesthetics Propofol and Halothane to Human Serum Albumin. High Resolution Crystal Structures
pubmed doi rcsb
molecule tags Carrier protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 204
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e78A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e78A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e78A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e78A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e78A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e78A05
4Z69A 3CX9A 3JQZA 5ID9A 2I2ZA 3B9MA 4BKEA 5ID7A 5DBYA 2VUFA 4L9QA 5HOZA 2BX8A 2BXKA 3V09A 4IW2A 2BXOA 4G03A 2BXQA 4N0FD 5FUOA 5IJEA 5IJFA 1LOTA 3LU7A 4L9KA 2BXCA 5IIHA 4ZBRA 2BXHA 2YDFA 4LB9A 4L8UA 4K71A 2BXDA 1BJ5A 1BKEA 2BXNA 1HK1A 2BXIA 3A73A 4OR0A 2VUEA 1HK2A 5IIXA 1E7HA 1UORA 5GHKA 1GNJA 4LA0A 3UIVA 2BXGA 1GNIA 4IW1A 2XW0A 2BXMA 3V08A 3JRYA 4HGMB 5DQFA 5IIUA 1HK4A 1H9ZA 3V03A 4HGKA 4F5SA 1O9XA 2BXAA 4F5VA 2I30A 2XSIA 4J2VA 3LU6A 1BM0A 4ZBQA 3SQJA 1J78A 1J7EA 1MA9A 4JK4A 1E7CA 4N0UD 1AO6A 1E7AA 4PO0A 3LU8A 1HK3A 4F5TA 2BXPA 4EMXA 4E99A 5IJ5A 4LUHA 1E78A 1HA2A 4G04A 4OT2A 2VDBA 1E7IA 4S1YA 1E7BA 3TDLA 1E7FA 1N5UA 2BXLA 3B9LA 1KW2A 2XVWA 4LUFA 2BXEA 1E7EA 1TF0A 1E7GA 2XW1A 2XVUA 1KXPD 4K2CA 4F5UA 2BXFA 2XVQA 5IFOA 1HK5A 2XVVA 4LB2A 2BXBA
chains in the Genus database with same CATH superfamily
4Z69A 3CX9A 2EFEA 3H3AA 1MUSA 2EFDA 2Z8JA 3JQZA 5ID9A 2V36A 3KIKA 2I2ZA 3B9MA 4BKEA 4N3ZA 4C31B 4ZCGA 1KDXA 2DBXA 5ID7A 3NVMA 3G9KD 2GUTA 3H37A 5DBYA 2VUFA 4L9QA 5HOZA 2BX8A 2BXKA 3V09A 2Z8IA 4MBEC 4IW2A 2AGHB 2DBWA 2BXOA 3MHSB 4G03A 2BXQA 4N0FD 5FUOA 5IJEA 5IJFA 1LOTA 2KBZA 3LU7A 4FK5B 4ZBKA 2LXSA 2BXCA 4L9KA 2LQIA 5IIHA 4FIPB 2BXHA 2QM6A 2YDFA 4LB9A 4ZBRA 4L8UA 5GINA 4K71A 1H5WA 2BXDA 1VZSA 1BJ5A 1BKEA 3PLAA 2BXNA 1HK1A 2BXIA 3A73A 4OR0A 2VUEA 1HK2A 4FJCB 4W4UB 3W1SA 4D7XA 3VQIA 5IIXA 1E7HA 1UORA 5GHKA 5GIOA 1GNJA 4LA0A 3SIUB 5D7GA 3UIVA 2DYOA 2BXGA 1GNIA 4G01A 2XW0A 4IW1A 4DHXB 4GDKB 2BXMA 4NAWB 1FOUA 3V08A 3GA9L 3JRYA 2KWFA 4HGMB 5DQFA 1NT2B 5IIUA 1HK4A 2LQHA 1H9ZA 4OTUA 2OT3A 1IJGA 3V03A 3WHRA 4HGKA 4F5SA 1O9XA 2BXAA 2EFCA 2I30A 2LOQA 2XSIA 4ZC6A 4F5VA 3NVKA 4ZUXV 1MIVA 4TQ0A 2AJEA 2JUHA 4J2VA 3LU6A 1BM0A 4ZBQA 3SQJA 5B5TA 1J78A 1J7EA 1MA9A 2DBUA 1TXUA 3GQUA 3FNMA 4JK4A 3BPJA 2EFHA 1E7CA 4BY9C 2OZBB 4N0UD 1AO6A 3SIVB 1E7AA 2CKXA 4GDLB 4PO0A 3M99C 3LU8A 1HK3A 4M70B 4F5TA 2BXPA 4EMXA 4E99A 5IJ5A 2K0NA 2DG5A 3NMUA 4LUHA 1VFIA 2LXTA 1E78A 1HA2A 3MHHB 4G04A 3ECPA 4OT2A 3NVIA 2NNWA 2VDBA 1E7IA 2E0XA 1E7BA 2QMCA 4S1YA 3TDLA 1E7FA 1MM8A 5BPKA 1SB0A 2Z8KA 2E0YA 4GDXA 1N5UA 5GIPA 2BXLA 3B9LA 1KW2A 1JNBA 2XVWA 4I9OA 4LUFA 1MIWA 2BXEA 3GQXA 1E7EA 1MUHA 1TF0A 2DYMA 1E7GA 4TQ1A 3WHSA 2XW1A 3ICXA 2ROHA 2XVUA 3FWBC 4GG2A 4WA6B 1KXPD 4K2CA 4F5UA 2BXFA 2QHBA 2XMOA 1MIYA 3FWCC 4OTTA 2XVQA 5IFOA 4Z9OA 3WHQA 2NQOA 1HK5A 4DM0A 2XVVA 3KJLA 1LNSA 3A75A 4LB2A 2BXBA
chains in the Genus database with same CATH topology
4Z69A 3CX9A 2EFEA 3H3AA 2EFDA 2Z8JA 3JQZA 5ID9A 2V36A 3KIKA 2I2ZA 3B9MA 4BKEA 4N3ZA 4C31B 4ZCGA 2DBXA 5ID7A 3NVMA 3G9KD 3H37A 5DBYA 2VUFA 4L9QA 5HOZA 2BX8A 2BXKA 3V09A 2Z8IA 4MBEC 4IW2A 2DBWA 2BXOA 3MHSB 4G03A 2BXQA 4N0FD 5FUOA 5IJEA 5IJFA 1LOTA 2KBZA 3LU7A 4FK5B 4ZBKA 4L9KA 2BXCA 5IIHA 4FIPB 2BXHA 2QM6A 2YDFA 4LB9A 4ZBRA 4L8UA 5GINA 4K71A 1H5WA 2BXDA 1VZSA 1BJ5A 1BKEA 3PLAA 2BXNA 1HK1A 2BXIA 3A73A 4OR0A 2VUEA 1HK2A 4FJCB 4W4UB 3W1SA 5IIXA 3VQIA 1E7HA 1UORA 5GHKA 5GIOA 1GNJA 4LA0A 3SIUB 5D7GA 3UIVA 2DYOA 2BXGA 1GNIA 4G01A 2XW0A 4IW1A 4DHXB 4GDKB 2BXMA 4NAWB 1FOUA 3V08A 3GA9L 3JRYA 4HGMB 5DQFA 1NT2B 5IIUA 1HK4A 4OTUA 1H9ZA 2OT3A 1IJGA 3V03A 3WHRA 4HGKA 4F5SA 1O9XA 2BXAA 2EFCA 2I30A 2LOQA 2XSIA 4ZC6A 4F5VA 3NVKA 4ZUXV 1MIVA 4TQ0A 2AJEA 2JUHA 4J2VA 3LU6A 1BM0A 4ZBQA 3SQJA 5B5TA 1J78A 1J7EA 1MA9A 2DBUA 1TXUA 3GQUA 3FNMA 4JK4A 2EFHA 1E7CA 4BY9C 2OZBB 4N0UD 1AO6A 3SIVB 1E7AA 2CKXA 4GDLB 4PO0A 3M99C 3LU8A 1HK3A 4M70B 4F5TA 2BXPA 4EMXA 4E99A 5IJ5A 2DG5A 3NMUA 4LUHA 1VFIA 1E78A 1HA2A 3MHHB 4G04A 4OT2A 3NVIA 2NNWA 2VDBA 1E7IA 2E0XA 1E7BA 2QMCA 4S1YA 3TDLA 1E7FA 5BPKA 2Z8KA 2E0YA 4GDXA 1N5UA 5GIPA 2BXLA 3B9LA 1KW2A 1JNBA 2XVWA 4LUFA 1MIWA 2BXEA 3GQXA 1E7EA 1TF0A 2DYMA 1E7GA 4TQ1A 3WHSA 2XW1A 3ICXA 2ROHA 2XVUA 3FWBC 4GG2A 4WA6B 1KXPD 4K2CA 4F5UA 2BXFA 2QHBA 2XMOA 1MIYA 3FWCC 4OTTA 2XVQA 5IFOA 4Z9OA 3WHQA 2NQOA 1HK5A 2XVVA 3KJLA 1LNSA 3A75A 4LB2A 2BXBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z69 A;  3CX9 A;  3JQZ A;  5ID9 A;  2I2Z A;  3B9M A;  4BKE A;  5ID7 A;  5DBY A;  2VUF A;  4L9Q A;  5HOZ A;  2BX8 A;  2BXK A;  3V09 A;  4IW2 A;  2BXO A;  4G03 A;  2BXQ A;  4N0F D;  5FUO A;  5IJE A;  5IJF A;  1LOT A;  3LU7 A;  4L9K A;  2BXC A;  5IIH A;  4ZBR A;  2BXH A;  2YDF A;  4LB9 A;  4L8U A;  4K71 A;  2BXD A;  1BJ5 A;  1BKE A;  2BXN A;  1HK1 A;  2BXI A;  3A73 A;  4OR0 A;  2VUE A;  1HK2 A;  5IIX A;  1E7H A;  1UOR A;  5GHK A;  1GNJ A;  4LA0 A;  3UIV A;  2BXG A;  1GNI A;  4IW1 A;  2XW0 A;  2BXM A;  3V08 A;  3JRY A;  4HGM B;  5DQF A;  5IIU A;  1HK4 A;  1H9Z A;  3V03 A;  4HGK A;  4F5S A;  1O9X A;  2BXA A;  4F5V A;  2I30 A;  2XSI A;  4J2V A;  3LU6 A;  1BM0 A;  4ZBQ A;  3SQJ A;  1J78 A;  1J7E A;  1MA9 A;  4JK4 A;  1E7C A;  4N0U D;  1AO6 A;  1E7A A;  4PO0 A;  3LU8 A;  1HK3 A;  4F5T A;  2BXP A;  4EMX A;  4E99 A;  5IJ5 A;  4LUH A;  1E78 A;  1HA2 A;  4G04 A;  4OT2 A;  2VDB A;  1E7I A;  4S1Y A;  1E7B A;  3TDL A;  1E7F A;  1N5U A;  2BXL A;  3B9L A;  1KW2 A;  2XVW A;  4LUF A;  2BXE A;  1E7E A;  1TF0 A;  1E7G A;  2XW1 A;  2XVU A;  1KXP D;  4K2C A;  4F5U A;  2BXF A;  2XVQ A;  5IFO A;  1HK5 A;  2XVV A;  4LB2 A;  2BXB A; 
#chains in the Genus database with same CATH topology
 4Z69 A;  3CX9 A;  2EFE A;  3H3A A;  1MUS A;  2EFD A;  2Z8J A;  3JQZ A;  5ID9 A;  2V36 A;  3KIK A;  2I2Z A;  3B9M A;  4BKE A;  4N3Z A;  4C31 B;  4ZCG A;  1KDX A;  2DBX A;  5ID7 A;  3NVM A;  3G9K D;  2GUT A;  3H37 A;  5DBY A;  2VUF A;  4L9Q A;  5HOZ A;  2BX8 A;  2BXK A;  3V09 A;  2Z8I A;  4MBE C;  4IW2 A;  2AGH B;  2DBW A;  2BXO A;  3MHS B;  4G03 A;  2BXQ A;  4N0F D;  5FUO A;  5IJE A;  5IJF A;  1LOT A;  2KBZ A;  3LU7 A;  4FK5 B;  4ZBK A;  2LXS A;  2BXC A;  4L9K A;  2LQI A;  5IIH A;  4FIP B;  2BXH A;  2QM6 A;  2YDF A;  4LB9 A;  4ZBR A;  4L8U A;  5GIN A;  4K71 A;  1H5W A;  2BXD A;  1VZS A;  1BJ5 A;  1BKE A;  3PLA A;  2BXN A;  1HK1 A;  2BXI A;  3A73 A;  4OR0 A;  2VUE A;  1HK2 A;  4FJC B;  4W4U B;  3W1S A;  4D7X A;  3VQI A;  5IIX A;  1E7H A;  1UOR A;  5GHK A;  5GIO A;  1GNJ A;  4LA0 A;  3SIU B;  5D7G A;  3UIV A;  2DYO A;  2BXG A;  1GNI A;  4G01 A;  2XW0 A;  4IW1 A;  4DHX B;  4GDK B;  2BXM A;  4NAW B;  1FOU A;  3V08 A;  3GA9 L;  3JRY A;  2KWF A;  4HGM B;  5DQF A;  1NT2 B;  5IIU A;  1HK4 A;  2LQH A;  1H9Z A;  4OTU A;  2OT3 A;  1IJG A;  3V03 A;  3WHR A;  4HGK A;  4F5S A;  1O9X A;  2BXA A;  2EFC A;  2I30 A;  2LOQ A;  2XSI A;  4ZC6 A;  4F5V A;  3NVK A;  4ZUX V;  1MIV A;  4TQ0 A;  2AJE A;  2JUH A;  4J2V A;  3LU6 A;  1BM0 A;  4ZBQ A;  3SQJ A;  5B5T A;  1J78 A;  1J7E A;  1MA9 A;  2DBU A;  1TXU A;  3GQU A;  3FNM A;  4JK4 A;  3BPJ A;  2EFH A;  1E7C A;  4BY9 C;  2OZB B;  4N0U D;  1AO6 A;  3SIV B;  1E7A A;  2CKX A;  4GDL B;  4PO0 A;  3M99 C;  3LU8 A;  1HK3 A;  4M70 B;  4F5T A;  2BXP A;  4EMX A;  4E99 A;  5IJ5 A;  2K0N A;  2DG5 A;  3NMU A;  4LUH A;  1VFI A;  2LXT A;  1E78 A;  1HA2 A;  3MHH B;  4G04 A;  3ECP A;  4OT2 A;  3NVI A;  2NNW A;  2VDB A;  1E7I A;  2E0X A;  1E7B A;  2QMC A;  4S1Y A;  3TDL A;  1E7F A;  1MM8 A;  5BPK A;  1SB0 A;  2Z8K A;  2E0Y A;  4GDX A;  1N5U A;  5GIP A;  2BXL A;  3B9L A;  1KW2 A;  1JNB A;  2XVW A;  4I9O A;  4LUF A;  1MIW A;  2BXE A;  3GQX A;  1E7E A;  1MUH A;  1TF0 A;  2DYM A;  1E7G A;  4TQ1 A;  3WHS A;  2XW1 A;  3ICX A;  2ROH A;  2XVU A;  3FWB C;  4GG2 A;  4WA6 B;  1KXP D;  4K2C A;  4F5U A;  2BXF A;  2QHB A;  2XMO A;  1MIY A;  3FWC C;  4OTT A;  2XVQ A;  5IFO A;  4Z9O A;  3WHQ A;  2NQO A;  1HK5 A;  4DM0 A;  2XVV A;  3KJL A;  1LNS A;  3A75 A;  4LB2 A;  2BXB A; 
#chains in the Genus database with same CATH homology
 4Z69 A;  3CX9 A;  2EFE A;  3H3A A;  2EFD A;  2Z8J A;  3JQZ A;  5ID9 A;  2V36 A;  3KIK A;  2I2Z A;  3B9M A;  4BKE A;  4N3Z A;  4C31 B;  4ZCG A;  2DBX A;  5ID7 A;  3NVM A;  3G9K D;  3H37 A;  5DBY A;  2VUF A;  4L9Q A;  5HOZ A;  2BX8 A;  2BXK A;  3V09 A;  2Z8I A;  4MBE C;  4IW2 A;  2DBW A;  2BXO A;  3MHS B;  4G03 A;  2BXQ A;  4N0F D;  5FUO A;  5IJE A;  5IJF A;  1LOT A;  2KBZ A;  3LU7 A;  4FK5 B;  4ZBK A;  4L9K A;  2BXC A;  5IIH A;  4FIP B;  2BXH A;  2QM6 A;  2YDF A;  4LB9 A;  4ZBR A;  4L8U A;  5GIN A;  4K71 A;  1H5W A;  2BXD A;  1VZS A;  1BJ5 A;  1BKE A;  3PLA A;  2BXN A;  1HK1 A;  2BXI A;  3A73 A;  4OR0 A;  2VUE A;  1HK2 A;  4FJC B;  4W4U B;  3W1S A;  5IIX A;  3VQI A;  1E7H A;  1UOR A;  5GHK A;  5GIO A;  1GNJ A;  4LA0 A;  3SIU B;  5D7G A;  3UIV A;  2DYO A;  2BXG A;  1GNI A;  4G01 A;  2XW0 A;  4IW1 A;  4DHX B;  4GDK B;  2BXM A;  4NAW B;  1FOU A;  3V08 A;  3GA9 L;  3JRY A;  4HGM B;  5DQF A;  1NT2 B;  5IIU A;  1HK4 A;  4OTU A;  1H9Z A;  2OT3 A;  1IJG A;  3V03 A;  3WHR A;  4HGK A;  4F5S A;  1O9X A;  2BXA A;  2EFC A;  2I30 A;  2LOQ A;  2XSI A;  4ZC6 A;  4F5V A;  3NVK A;  4ZUX V;  1MIV A;  4TQ0 A;  2AJE A;  2JUH A;  4J2V A;  3LU6 A;  1BM0 A;  4ZBQ A;  3SQJ A;  5B5T A;  1J78 A;  1J7E A;  1MA9 A;  2DBU A;  1TXU A;  3GQU A;  3FNM A;  4JK4 A;  2EFH A;  1E7C A;  4BY9 C;  2OZB B;  4N0U D;  1AO6 A;  3SIV B;  1E7A A;  2CKX A;  4GDL B;  4PO0 A;  3M99 C;  3LU8 A;  1HK3 A;  4M70 B;  4F5T A;  2BXP A;  4EMX A;  4E99 A;  5IJ5 A;  2DG5 A;  3NMU A;  4LUH A;  1VFI A;  1E78 A;  1HA2 A;  3MHH B;  4G04 A;  4OT2 A;  3NVI A;  2NNW A;  2VDB A;  1E7I A;  2E0X A;  1E7B A;  2QMC A;  4S1Y A;  3TDL A;  1E7F A;  5BPK A;  2Z8K A;  2E0Y A;  4GDX A;  1N5U A;  5GIP A;  2BXL A;  3B9L A;  1KW2 A;  1JNB A;  2XVW A;  4LUF A;  1MIW A;  2BXE A;  3GQX A;  1E7E A;  1TF0 A;  2DYM A;  1E7G A;  4TQ1 A;  3WHS A;  2XW1 A;  3ICX A;  2ROH A;  2XVU A;  3FWB C;  4GG2 A;  4WA6 B;  1KXP D;  4K2C A;  4F5U A;  2BXF A;  2QHB A;  2XMO A;  1MIY A;  3FWC C;  4OTT A;  2XVQ A;  5IFO A;  4Z9O A;  3WHQ A;  2NQO A;  1HK5 A;  2XVV A;  3KJL A;  1LNS A;  3A75 A;  4LB2 A;  2BXB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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