1J7EA

A structural basis for the unique binding features of the human vitamin d-binding protein
Total Genus 159
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
451
structure length
435
Chain Sequence
YEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCDTRTSALSAKSCSPFPVHPGTAECCTKRKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A structural basis for the unique binding features of the human vitamin D-binding protein.
pubmed doi rcsb
molecule tags Transport, ligand binding protein
molecule keywords vitamin D binding protein
total genus 159
structure length 435
sequence length 451
chains with identical sequence B
ec nomenclature
pdb deposition date 2001-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
A PF09164 VitD-bind_III Vitamin D binding protein, domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1j7eA05
1E78A 5IFOA 2XVVA 4BKEA 1HK2A 3A73A 1N5UA 3B9LA 1HK1A 5DQFA 2VUFA 2VDBA 1BM0A 3JRYA 1HK3A 4L8UA 1KXPD 2BXEA 2XVUA 3LU8A 4L9KA 4F5SA 4F5UA 3SQJA 1LOTA 1BKEA 4LB9A 4J2VA 2I2ZA 2BXKA 2XW0A 1E7CA 1E7HA 4PO0A 1GNIA 2BXGA 4ZBQA 5ID7A 1H9ZA 3CX9A 2BXBA 2YDFA 4G03A 4N0UD 4LUHA 3LU6A 4LA0A 2BXCA 5HOZA 2XVQA 2BXNA 4F5VA 2BXQA 2I30A 2BXOA 2BXLA 4N0FD 3UIVA 2BXAA 2BXHA 5IIUA 2BXMA 5ID9A 1J7EA 2XSIA 4JK4A 4F5TA 1E7IA 1E7FA 5IJEA 2XVWA 5IJFA 5GHKA 5DBYA 4OR0A 2BXDA 3JQZA 3LU7A 1HK4A 4ZBRA 3V08A 4K71A 1TF0A 2VUEA 4K2CA 1E7AA 4L9QA 4LUFA 4EMXA 3TDLA 3V03A 5IIXA 2BXPA 1HA2A 1UORA 4OT2A 4IW2A 1E7GA 1KW2A 5IIHA 4LB2A 4G04A 4HGMB 4IW1A 4Z69A 1E7BA 1J78A 4S1YA 1AO6A 2BXFA 1HK5A 1O9XA 2BX8A 2XW1A 1E7EA 3V09A 4HGKA 2BXIA 1BJ5A 5FUOA 3B9MA 4E99A 5IJ5A 1MA9A 1GNJA
chains in the Genus database with same CATH superfamily
3BPJA 5B5TA 4GDLB 1E78A 4GG2A 5IFOA 2KWFA 2XVVA 3GQUA 2EFCA 1MIWA 3KIKA 4BKEA 1NT2B 3A75A 1HK2A 3VQIA 3A73A 4Z9OA 1N5UA 4C31B 3B9LA 4FIPB 4BY9C 1HK1A 5DQFA 2VUFA 2DG5A 3FWBC 3FNMA 4D7XA 2VDBA 5GINA 1BM0A 2KBZA 5D7GA 3JRYA 1HK3A 4GDKB 4L8UA 4NAWB 1KXPD 2BXEA 2XVUA 2GUTA 2QMCA 3LU8A 4L9KA 2V36A 4F5SA 4F5UA 2DYMA 2K0NA 3SQJA 1MM8A 1LOTA 1LNSA 4M70B 1BKEA 4LB9A 3FWCC 4MBEC 2Z8JA 3G9KD 4J2VA 2I2ZA 2BXKA 2XW0A 1E7CA 1E7HA 1MUHA 4PO0A 1GNIA 2BXGA 1H5WA 2EFEA 3WHRA 4DM0A 4ZBQA 5ID7A 1H9ZA 2DYOA 2E0YA 3CX9A 2BXBA 2YDFA 3GQXA 4G03A 1MUSA 4N0UD 3H37A 4LUHA 3LU6A 4LA0A 3ECPA 2BXCA 5HOZA 2XVQA 2Z8IA 4G01A 2BXNA 4TQ1A 3ICXA 4F5VA 2BXQA 2I30A 3WHSA 2BXOA 4ZBKA 2BXLA 4GDXA 3NVMA 2JUHA 4N0FD 3UIVA 2BXAA 3W1SA 2BXHA 2EFDA 1VZSA 5IIUA 2BXMA 2OT3A 1JNBA 5ID9A 4ZCGA 1J7EA 2XSIA 2LOQA 3GA9L 4JK4A 4F5TA 1MIYA 2NQOA 2ROHA 1E7IA 2QM6A 2LQHA 4TQ0A 3SIVB 1KDXA 2NNWA 5BPKA 1E7FA 5IJEA 2Z8KA 2XVWA 5IJFA 5GHKA 5DBYA 2LXTA 4OR0A 5GIPA 3NVKA 2AJEA 2BXDA 3JQZA 3LU7A 2XMOA 2LQIA 1HK4A 4ZBRA 3V08A 4K71A 1VFIA 4OTTA 1FOUA 1TF0A 2VUEA 4K2CA 1E7AA 4L9QA 4LUFA 3WHQA 4EMXA 2AGHB 3MHSB 3TDLA 3V03A 2CKXA 4DHXB 4FJCB 5IIXA 5GIOA 2BXPA 2OZBB 4WA6B 1IJGA 1HA2A 1UORA 3MHHB 4OT2A 4IW2A 4I9OA 3M99C 1E7GA 1KW2A 1TXUA 5IIHA 4LB2A 4G04A 2E0XA 4HGMB 3NMUA 1MIVA 4IW1A 4Z69A 1E7BA 2DBXA 1J78A 4S1YA 4ZC6A 3SIUB 1AO6A 2BXFA 1HK5A 1O9XA 2BX8A 2XW1A 1E7EA 4W4UB 3V09A 4HGKA 2EFHA 1SB0A 2DBUA 2BXIA 1BJ5A 5FUOA 2LXSA 3B9MA 3NVIA 4FK5B 3KJLA 3H3AA 4OTUA 4E99A 2DBWA 5IJ5A 1MA9A 4ZUXV 2QHBA 3PLAA 1GNJA 4N3ZA
chains in the Genus database with same CATH topology
5B5TA 4GDLB 1E78A 4GG2A 5IFOA 3GQUA 2XVVA 2EFCA 1MIWA 3KIKA 4BKEA 1NT2B 3A75A 1HK2A 3VQIA 3A73A 4Z9OA 1N5UA 4C31B 3B9LA 4FIPB 4BY9C 1HK1A 5DQFA 2VUFA 2DG5A 3FWBC 3FNMA 5GINA 2VDBA 1BM0A 2KBZA 5D7GA 3JRYA 1HK3A 4GDKB 4L8UA 4NAWB 1KXPD 2BXEA 2XVUA 2QMCA 3LU8A 4L9KA 2V36A 4F5SA 4F5UA 2DYMA 3SQJA 1LOTA 1LNSA 4M70B 1BKEA 4LB9A 3FWCC 4MBEC 2Z8JA 3G9KD 4J2VA 2I2ZA 2BXKA 2XW0A 1E7CA 1E7HA 4PO0A 1GNIA 2BXGA 1H5WA 2EFEA 3WHRA 4ZBQA 5ID7A 1H9ZA 2DYOA 2E0YA 3CX9A 2BXBA 2YDFA 3GQXA 4G03A 4N0UD 3H37A 4LUHA 3LU6A 4LA0A 2BXCA 5HOZA 2XVQA 2Z8IA 4G01A 2BXNA 4TQ1A 3ICXA 4F5VA 2BXQA 2I30A 3WHSA 2BXOA 4ZBKA 2BXLA 4GDXA 3NVMA 2JUHA 4N0FD 3UIVA 2BXAA 3W1SA 2BXHA 2EFDA 1VZSA 5IIUA 2BXMA 2OT3A 1JNBA 5ID9A 4ZCGA 1J7EA 2XSIA 2LOQA 3GA9L 4JK4A 4F5TA 1MIYA 2NQOA 2ROHA 1E7IA 2QM6A 4TQ0A 3SIVB 2NNWA 5BPKA 1E7FA 5IJEA 2Z8KA 2XVWA 5IJFA 5GHKA 5DBYA 4OR0A 5GIPA 3NVKA 2AJEA 2BXDA 3JQZA 3LU7A 2XMOA 1HK4A 4ZBRA 3V08A 4K71A 1VFIA 4OTTA 1FOUA 1TF0A 2VUEA 4K2CA 1E7AA 4L9QA 4LUFA 3WHQA 4EMXA 3TDLA 3MHSB 3V03A 2CKXA 4DHXB 4FJCB 5IIXA 5GIOA 2BXPA 2OZBB 4WA6B 1IJGA 1HA2A 1UORA 3MHHB 4OT2A 4IW2A 3M99C 1E7GA 1KW2A 1TXUA 5IIHA 4LB2A 4G04A 2E0XA 4HGMB 3NMUA 1MIVA 4IW1A 4Z69A 1E7BA 2DBXA 1J78A 4S1YA 4ZC6A 3SIUB 1AO6A 2BXFA 1HK5A 1O9XA 2BX8A 2XW1A 1E7EA 4W4UB 3V09A 4HGKA 2EFHA 2DBUA 2BXIA 1BJ5A 5FUOA 3B9MA 3NVIA 4FK5B 3KJLA 3H3AA 4OTUA 4E99A 2DBWA 5IJ5A 1MA9A 4ZUXV 2QHBA 3PLAA 1GNJA 4N3ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E78 A;  5IFO A;  2XVV A;  4BKE A;  1HK2 A;  3A73 A;  1N5U A;  3B9L A;  1HK1 A;  5DQF A;  2VUF A;  2VDB A;  1BM0 A;  3JRY A;  1HK3 A;  4L8U A;  1KXP D;  2BXE A;  2XVU A;  3LU8 A;  4L9K A;  4F5S A;  4F5U A;  3SQJ A;  1LOT A;  1BKE A;  4LB9 A;  4J2V A;  2I2Z A;  2BXK A;  2XW0 A;  1E7C A;  1E7H A;  4PO0 A;  1GNI A;  2BXG A;  4ZBQ A;  5ID7 A;  1H9Z A;  3CX9 A;  2BXB A;  2YDF A;  4G03 A;  4N0U D;  4LUH A;  3LU6 A;  4LA0 A;  2BXC A;  5HOZ A;  2XVQ A;  2BXN A;  4F5V A;  2BXQ A;  2I30 A;  2BXO A;  2BXL A;  4N0F D;  3UIV A;  2BXA A;  2BXH A;  5IIU A;  2BXM A;  5ID9 A;  1J7E A;  2XSI A;  4JK4 A;  4F5T A;  1E7I A;  1E7F A;  5IJE A;  2XVW A;  5IJF A;  5GHK A;  5DBY A;  4OR0 A;  2BXD A;  3JQZ A;  3LU7 A;  1HK4 A;  4ZBR A;  3V08 A;  4K71 A;  1TF0 A;  2VUE A;  4K2C A;  1E7A A;  4L9Q A;  4LUF A;  4EMX A;  3TDL A;  3V03 A;  5IIX A;  2BXP A;  1HA2 A;  1UOR A;  4OT2 A;  4IW2 A;  1E7G A;  1KW2 A;  5IIH A;  4LB2 A;  4G04 A;  4HGM B;  4IW1 A;  4Z69 A;  1E7B A;  1J78 A;  4S1Y A;  1AO6 A;  2BXF A;  1HK5 A;  1O9X A;  2BX8 A;  2XW1 A;  1E7E A;  3V09 A;  4HGK A;  2BXI A;  1BJ5 A;  5FUO A;  3B9M A;  4E99 A;  5IJ5 A;  1MA9 A;  1GNJ A; 
#chains in the Genus database with same CATH topology
 3BPJ A;  5B5T A;  4GDL B;  1E78 A;  4GG2 A;  5IFO A;  2KWF A;  2XVV A;  3GQU A;  2EFC A;  1MIW A;  3KIK A;  4BKE A;  1NT2 B;  3A75 A;  1HK2 A;  3VQI A;  3A73 A;  4Z9O A;  1N5U A;  4C31 B;  3B9L A;  4FIP B;  4BY9 C;  1HK1 A;  5DQF A;  2VUF A;  2DG5 A;  3FWB C;  3FNM A;  4D7X A;  2VDB A;  5GIN A;  1BM0 A;  2KBZ A;  5D7G A;  3JRY A;  1HK3 A;  4GDK B;  4L8U A;  4NAW B;  1KXP D;  2BXE A;  2XVU A;  2GUT A;  2QMC A;  3LU8 A;  4L9K A;  2V36 A;  4F5S A;  4F5U A;  2DYM A;  2K0N A;  3SQJ A;  1MM8 A;  1LOT A;  1LNS A;  4M70 B;  1BKE A;  4LB9 A;  3FWC C;  4MBE C;  2Z8J A;  3G9K D;  4J2V A;  2I2Z A;  2BXK A;  2XW0 A;  1E7C A;  1E7H A;  1MUH A;  4PO0 A;  1GNI A;  2BXG A;  1H5W A;  2EFE A;  3WHR A;  4DM0 A;  4ZBQ A;  5ID7 A;  1H9Z A;  2DYO A;  2E0Y A;  3CX9 A;  2BXB A;  2YDF A;  3GQX A;  4G03 A;  1MUS A;  4N0U D;  3H37 A;  4LUH A;  3LU6 A;  4LA0 A;  3ECP A;  2BXC A;  5HOZ A;  2XVQ A;  2Z8I A;  4G01 A;  2BXN A;  4TQ1 A;  3ICX A;  4F5V A;  2BXQ A;  2I30 A;  3WHS A;  2BXO A;  4ZBK A;  2BXL A;  4GDX A;  3NVM A;  2JUH A;  4N0F D;  3UIV A;  2BXA A;  3W1S A;  2BXH A;  2EFD A;  1VZS A;  5IIU A;  2BXM A;  2OT3 A;  1JNB A;  5ID9 A;  4ZCG A;  1J7E A;  2XSI A;  2LOQ A;  3GA9 L;  4JK4 A;  4F5T A;  1MIY A;  2NQO A;  2ROH A;  1E7I A;  2QM6 A;  2LQH A;  4TQ0 A;  3SIV B;  1KDX A;  2NNW A;  5BPK A;  1E7F A;  5IJE A;  2Z8K A;  2XVW A;  5IJF A;  5GHK A;  5DBY A;  2LXT A;  4OR0 A;  5GIP A;  3NVK A;  2AJE A;  2BXD A;  3JQZ A;  3LU7 A;  2XMO A;  2LQI A;  1HK4 A;  4ZBR A;  3V08 A;  4K71 A;  1VFI A;  4OTT A;  1FOU A;  1TF0 A;  2VUE A;  4K2C A;  1E7A A;  4L9Q A;  4LUF A;  3WHQ A;  4EMX A;  2AGH B;  3MHS B;  3TDL A;  3V03 A;  2CKX A;  4DHX B;  4FJC B;  5IIX A;  5GIO A;  2BXP A;  2OZB B;  4WA6 B;  1IJG A;  1HA2 A;  1UOR A;  3MHH B;  4OT2 A;  4IW2 A;  4I9O A;  3M99 C;  1E7G A;  1KW2 A;  1TXU A;  5IIH A;  4LB2 A;  4G04 A;  2E0X A;  4HGM B;  3NMU A;  1MIV A;  4IW1 A;  4Z69 A;  1E7B A;  2DBX A;  1J78 A;  4S1Y A;  4ZC6 A;  3SIU B;  1AO6 A;  2BXF A;  1HK5 A;  1O9X A;  2BX8 A;  2XW1 A;  1E7E A;  4W4U B;  3V09 A;  4HGK A;  2EFH A;  1SB0 A;  2DBU A;  2BXI A;  1BJ5 A;  5FUO A;  2LXS A;  3B9M A;  3NVI A;  4FK5 B;  3KJL A;  3H3A A;  4OTU A;  4E99 A;  2DBW A;  5IJ5 A;  1MA9 A;  4ZUX V;  2QHB A;  3PLA A;  1GNJ A;  4N3Z A; 
#chains in the Genus database with same CATH homology
 5B5T A;  4GDL B;  1E78 A;  4GG2 A;  5IFO A;  3GQU A;  2XVV A;  2EFC A;  1MIW A;  3KIK A;  4BKE A;  1NT2 B;  3A75 A;  1HK2 A;  3VQI A;  3A73 A;  4Z9O A;  1N5U A;  4C31 B;  3B9L A;  4FIP B;  4BY9 C;  1HK1 A;  5DQF A;  2VUF A;  2DG5 A;  3FWB C;  3FNM A;  5GIN A;  2VDB A;  1BM0 A;  2KBZ A;  5D7G A;  3JRY A;  1HK3 A;  4GDK B;  4L8U A;  4NAW B;  1KXP D;  2BXE A;  2XVU A;  2QMC A;  3LU8 A;  4L9K A;  2V36 A;  4F5S A;  4F5U A;  2DYM A;  3SQJ A;  1LOT A;  1LNS A;  4M70 B;  1BKE A;  4LB9 A;  3FWC C;  4MBE C;  2Z8J A;  3G9K D;  4J2V A;  2I2Z A;  2BXK A;  2XW0 A;  1E7C A;  1E7H A;  4PO0 A;  1GNI A;  2BXG A;  1H5W A;  2EFE A;  3WHR A;  4ZBQ A;  5ID7 A;  1H9Z A;  2DYO A;  2E0Y A;  3CX9 A;  2BXB A;  2YDF A;  3GQX A;  4G03 A;  4N0U D;  3H37 A;  4LUH A;  3LU6 A;  4LA0 A;  2BXC A;  5HOZ A;  2XVQ A;  2Z8I A;  4G01 A;  2BXN A;  4TQ1 A;  3ICX A;  4F5V A;  2BXQ A;  2I30 A;  3WHS A;  2BXO A;  4ZBK A;  2BXL A;  4GDX A;  3NVM A;  2JUH A;  4N0F D;  3UIV A;  2BXA A;  3W1S A;  2BXH A;  2EFD A;  1VZS A;  5IIU A;  2BXM A;  2OT3 A;  1JNB A;  5ID9 A;  4ZCG A;  1J7E A;  2XSI A;  2LOQ A;  3GA9 L;  4JK4 A;  4F5T A;  1MIY A;  2NQO A;  2ROH A;  1E7I A;  2QM6 A;  4TQ0 A;  3SIV B;  2NNW A;  5BPK A;  1E7F A;  5IJE A;  2Z8K A;  2XVW A;  5IJF A;  5GHK A;  5DBY A;  4OR0 A;  5GIP A;  3NVK A;  2AJE A;  2BXD A;  3JQZ A;  3LU7 A;  2XMO A;  1HK4 A;  4ZBR A;  3V08 A;  4K71 A;  1VFI A;  4OTT A;  1FOU A;  1TF0 A;  2VUE A;  4K2C A;  1E7A A;  4L9Q A;  4LUF A;  3WHQ A;  4EMX A;  3TDL A;  3MHS B;  3V03 A;  2CKX A;  4DHX B;  4FJC B;  5IIX A;  5GIO A;  2BXP A;  2OZB B;  4WA6 B;  1IJG A;  1HA2 A;  1UOR A;  3MHH B;  4OT2 A;  4IW2 A;  3M99 C;  1E7G A;  1KW2 A;  1TXU A;  5IIH A;  4LB2 A;  4G04 A;  2E0X A;  4HGM B;  3NMU A;  1MIV A;  4IW1 A;  4Z69 A;  1E7B A;  2DBX A;  1J78 A;  4S1Y A;  4ZC6 A;  3SIU B;  1AO6 A;  2BXF A;  1HK5 A;  1O9X A;  2BX8 A;  2XW1 A;  1E7E A;  4W4U B;  3V09 A;  4HGK A;  2EFH A;  2DBU A;  2BXI A;  1BJ5 A;  5FUO A;  3B9M A;  3NVI A;  4FK5 B;  3KJL A;  3H3A A;  4OTU A;  4E99 A;  2DBW A;  5IJ5 A;  1MA9 A;  4ZUX V;  2QHB A;  3PLA A;  1GNJ A;  4N3Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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