1KW2A

Crystal structure of uncomplexed vitamin d-binding protein
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
455
structure length
455
Chain Sequence
GRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPKELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the vitamin D-binding protein and its complex with actin: structural basis of the actin-scavenger system.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Vitamin D-binding protein
total genus 175
structure length 455
sequence length 455
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
A PF09164 VitD-bind_III Vitamin D binding protein, domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A05
2BXMA 2BXBA 1GNJA 2XW1A 1E78A 3TDLA 3V09A 2XVUA 1O9XA 1N5UA 4L8UA 5DQFA 4ZBQA 2VDBA 4EMXA 5IIUA 5ID7A 2BXNA 5IFOA 2I30A 1KW2A 2BXKA 1BJ5A 1HK5A 4IW1A 1E7IA 4J2VA 4Z69A 2BXGA 1E7AA 2BXOA 3A73A 2BXCA 4OT2A 4LA0A 5IJEA 4F5UA 3LU7A 1HK2A 1HK3A 3B9MA 2BX8A 4HGKA 4OR0A 1H9ZA 3JQZA 1AO6A 3V03A 2XSIA 1E7BA 1E7CA 1GNIA 5FUOA 4LUHA 1E7GA 1E7HA 4LUFA 4N0FD 1UORA 1HA2A 1TF0A 2BXQA 2BXEA 4F5SA 5IIXA 5IJ5A 3UIVA 1HK4A 2BXAA 1J78A 4F5VA 1E7FA 3CX9A 4L9KA 1BKEA 4G03A 4L9QA 4HGMB 2BXHA 2BXIA 4PO0A 1BM0A 4LB9A 5GHKA 4N0UD 5DBYA 4JK4A 1MA9A 4F5TA 4S1YA 3B9LA 2VUFA 2BXFA 2XVQA 3V08A 4IW2A 1E7EA 2BXLA 2XVWA 5HOZA 1J7EA 4G04A 4BKEA 2I2ZA 2VUEA 2XVVA 2YDFA 3LU8A 4ZBRA 2BXPA 3LU6A 4E99A 4LB2A 4K2CA 5IJFA 3SQJA 2XW0A 1KXPD 4K71A 5IIHA 2BXDA 5ID9A 1HK1A 3JRYA 1LOTA
chains in the Genus database with same CATH superfamily
2QM6A 3KIKA 2LXTA 4DM0A 3VQIA 2BXMA 2BXBA 1GNJA 2XW1A 4M70B 3WHRA 3H3AA 1E78A 3GA9L 3TDLA 3V09A 2XVUA 1MIWA 2E0YA 1O9XA 1N5UA 2Z8KA 2EFHA 4L8UA 5DQFA 2OZBB 3M99C 4ZBQA 4WA6B 4FIPB 2VDBA 4EMXA 5IIUA 5ID7A 1MM8A 2BXNA 2AGHB 5IFOA 2I30A 1KW2A 4ZBKA 3WHQA 2BXKA 2KWFA 4OTTA 5GIOA 2LQHA 1BJ5A 1HK5A 4IW1A 2DYOA 1MIVA 4NAWB 1E7IA 1LNSA 4J2VA 4OTUA 1VFIA 2AJEA 1KDXA 2DBUA 2LXSA 4C31B 4Z69A 3GQXA 3FNMA 2BXGA 1E7AA 2BXOA 3A73A 2EFDA 2OT3A 2BXCA 4OT2A 4LA0A 3KJLA 5IJEA 3NVKA 4F5UA 2NNWA 3PLAA 3NMUA 2DBXA 2DBWA 3LU7A 1HK2A 1HK3A 3WHSA 3B9MA 1FOUA 2BX8A 4HGKA 4OR0A 4Z9OA 1H9ZA 1TXUA 3JQZA 1NT2B 1AO6A 3H37A 3SIUB 3V03A 1H5WA 2XSIA 1E7BA 4GDXA 2JUHA 1E7CA 3W1SA 4G01A 1GNIA 5FUOA 1JNBA 4LUHA 2E0XA 1E7GA 5GINA 1E7HA 4LUFA 4TQ1A 4N0FD 4GG2A 1UORA 3ICXA 1HA2A 1TF0A 2BXQA 3GQUA 4GDKB 2BXEA 4F5SA 2DYMA 5IJ5A 3UIVA 5IIXA 1HK4A 2BXAA 3NVIA 1J78A 4F5VA 1E7FA 3CX9A 2K0NA 4N3ZA 4L9KA 2LOQA 1BKEA 2EFCA 4G03A 3BPJA 2DG5A 4L9QA 4W4UB 4ZC6A 4ZUXV 1MUSA 4HGMB 1VZSA 2BXHA 2BXIA 2EFEA 1BM0A 2XMOA 3MHSB 4FK5B 4LB9A 2GUTA 4PO0A 5GHKA 4N0UD 5BPKA 4D7XA 4FJCB 2NQOA 2Z8JA 3FWBC 5DBYA 2ROHA 3ECPA 4JK4A 1MA9A 3MHHB 4F5TA 5B5TA 1MIYA 3A75A 3FWCC 4S1YA 2KBZA 3B9LA 2VUFA 2BXFA 2XVQA 3V08A 1SB0A 1E7EA 2Z8IA 2BXLA 4IW2A 2QMCA 3SIVB 2QHBA 2XVWA 5HOZA 1MUHA 1J7EA 4G04A 4BKEA 2I2ZA 2VUEA 2XVVA 2YDFA 4I9OA 4GDLB 2V36A 3LU8A 4ZBRA 4DHXB 2BXPA 3LU6A 4E99A 4TQ0A 4LB2A 4K2CA 5IJFA 2CKXA 4ZCGA 3SQJA 2XW0A 5GIPA 1IJGA 1KXPD 4K71A 5D7GA 4BY9C 5IIHA 2BXDA 3NVMA 5ID9A 1HK1A 3JRYA 4MBEC 2LQIA 3G9KD 1LOTA
chains in the Genus database with same CATH topology
2QM6A 3KIKA 3VQIA 2BXMA 2BXBA 1GNJA 2XW1A 4M70B 3WHRA 3H3AA 1E78A 3GA9L 3TDLA 3V09A 2XVUA 1MIWA 2E0YA 1O9XA 1N5UA 2Z8KA 2EFHA 4L8UA 5DQFA 2OZBB 3M99C 4ZBQA 4WA6B 4FIPB 2VDBA 4EMXA 5IIUA 5ID7A 2BXNA 5IFOA 2I30A 1KW2A 4ZBKA 3WHQA 2BXKA 4OTTA 5GIOA 1BJ5A 1HK5A 4IW1A 2DYOA 1MIVA 4NAWB 1E7IA 1LNSA 4J2VA 4OTUA 1VFIA 2AJEA 2DBUA 4Z69A 3GQXA 3FNMA 2BXGA 1E7AA 2BXOA 3A73A 2EFDA 2OT3A 2BXCA 4OT2A 4LA0A 3KJLA 5IJEA 3NVKA 4F5UA 2NNWA 3PLAA 3NMUA 2DBXA 2DBWA 3LU7A 1HK2A 1HK3A 3WHSA 3B9MA 1FOUA 2BX8A 4HGKA 4OR0A 4Z9OA 1H9ZA 1TXUA 3JQZA 1NT2B 1AO6A 3H37A 3SIUB 3V03A 1H5WA 2XSIA 1E7BA 4GDXA 2JUHA 1E7CA 3W1SA 4G01A 1GNIA 5FUOA 1JNBA 4LUHA 2E0XA 1E7GA 5GINA 1E7HA 4LUFA 4TQ1A 4N0FD 4GG2A 1UORA 3ICXA 1HA2A 1TF0A 2BXQA 3GQUA 4GDKB 2BXEA 4F5SA 2DYMA 5IJ5A 3UIVA 5IIXA 1HK4A 2BXAA 3NVIA 1J78A 4F5VA 1E7FA 3CX9A 4N3ZA 4L9KA 2LOQA 1BKEA 2EFCA 4G03A 4L9QA 2DG5A 4W4UB 4ZC6A 4ZUXV 4HGMB 1VZSA 2BXHA 2BXIA 2EFEA 1BM0A 2XMOA 3MHSB 4FK5B 4LB9A 4PO0A 5GHKA 4C31B 4N0UD 5BPKA 4FJCB 2NQOA 2Z8JA 3FWBC 5DBYA 2ROHA 4JK4A 1MA9A 3MHHB 4F5TA 5B5TA 1MIYA 3A75A 3FWCC 4S1YA 2KBZA 3B9LA 2VUFA 2BXFA 2XVQA 3V08A 4IW2A 1E7EA 2Z8IA 2BXLA 2QMCA 3SIVB 2QHBA 2XVWA 5HOZA 1J7EA 4G04A 4BKEA 2I2ZA 2VUEA 2XVVA 2YDFA 4GDLB 2V36A 3LU8A 4ZBRA 4DHXB 2BXPA 3LU6A 4E99A 4TQ0A 4LB2A 4K2CA 5IJFA 2CKXA 4ZCGA 3SQJA 2XW0A 5GIPA 1IJGA 1KXPD 4K71A 5D7GA 4BY9C 5IIHA 2BXDA 3NVMA 5ID9A 1HK1A 3JRYA 4MBEC 3G9KD 1LOTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXM A;  2BXB A;  1GNJ A;  2XW1 A;  1E78 A;  3TDL A;  3V09 A;  2XVU A;  1O9X A;  1N5U A;  4L8U A;  5DQF A;  4ZBQ A;  2VDB A;  4EMX A;  5IIU A;  5ID7 A;  2BXN A;  5IFO A;  2I30 A;  1KW2 A;  2BXK A;  1BJ5 A;  1HK5 A;  4IW1 A;  1E7I A;  4J2V A;  4Z69 A;  2BXG A;  1E7A A;  2BXO A;  3A73 A;  2BXC A;  4OT2 A;  4LA0 A;  5IJE A;  4F5U A;  3LU7 A;  1HK2 A;  1HK3 A;  3B9M A;  2BX8 A;  4HGK A;  4OR0 A;  1H9Z A;  3JQZ A;  1AO6 A;  3V03 A;  2XSI A;  1E7B A;  1E7C A;  1GNI A;  5FUO A;  4LUH A;  1E7G A;  1E7H A;  4LUF A;  4N0F D;  1UOR A;  1HA2 A;  1TF0 A;  2BXQ A;  2BXE A;  4F5S A;  5IIX A;  5IJ5 A;  3UIV A;  1HK4 A;  2BXA A;  1J78 A;  4F5V A;  1E7F A;  3CX9 A;  4L9K A;  1BKE A;  4G03 A;  4L9Q A;  4HGM B;  2BXH A;  2BXI A;  4PO0 A;  1BM0 A;  4LB9 A;  5GHK A;  4N0U D;  5DBY A;  4JK4 A;  1MA9 A;  4F5T A;  4S1Y A;  3B9L A;  2VUF A;  2BXF A;  2XVQ A;  3V08 A;  4IW2 A;  1E7E A;  2BXL A;  2XVW A;  5HOZ A;  1J7E A;  4G04 A;  4BKE A;  2I2Z A;  2VUE A;  2XVV A;  2YDF A;  3LU8 A;  4ZBR A;  2BXP A;  3LU6 A;  4E99 A;  4LB2 A;  4K2C A;  5IJF A;  3SQJ A;  2XW0 A;  1KXP D;  4K71 A;  5IIH A;  2BXD A;  5ID9 A;  1HK1 A;  3JRY A;  1LOT A; 
#chains in the Genus database with same CATH topology
 2QM6 A;  3KIK A;  2LXT A;  4DM0 A;  3VQI A;  2BXM A;  2BXB A;  1GNJ A;  2XW1 A;  4M70 B;  3WHR A;  3H3A A;  1E78 A;  3GA9 L;  3TDL A;  3V09 A;  2XVU A;  1MIW A;  2E0Y A;  1O9X A;  1N5U A;  2Z8K A;  2EFH A;  4L8U A;  5DQF A;  2OZB B;  3M99 C;  4ZBQ A;  4WA6 B;  4FIP B;  2VDB A;  4EMX A;  5IIU A;  5ID7 A;  1MM8 A;  2BXN A;  2AGH B;  5IFO A;  2I30 A;  1KW2 A;  4ZBK A;  3WHQ A;  2BXK A;  2KWF A;  4OTT A;  5GIO A;  2LQH A;  1BJ5 A;  1HK5 A;  4IW1 A;  2DYO A;  1MIV A;  4NAW B;  1E7I A;  1LNS A;  4J2V A;  4OTU A;  1VFI A;  2AJE A;  1KDX A;  2DBU A;  2LXS A;  4C31 B;  4Z69 A;  3GQX A;  3FNM A;  2BXG A;  1E7A A;  2BXO A;  3A73 A;  2EFD A;  2OT3 A;  2BXC A;  4OT2 A;  4LA0 A;  3KJL A;  5IJE A;  3NVK A;  4F5U A;  2NNW A;  3PLA A;  3NMU A;  2DBX A;  2DBW A;  3LU7 A;  1HK2 A;  1HK3 A;  3WHS A;  3B9M A;  1FOU A;  2BX8 A;  4HGK A;  4OR0 A;  4Z9O A;  1H9Z A;  1TXU A;  3JQZ A;  1NT2 B;  1AO6 A;  3H37 A;  3SIU B;  3V03 A;  1H5W A;  2XSI A;  1E7B A;  4GDX A;  2JUH A;  1E7C A;  3W1S A;  4G01 A;  1GNI A;  5FUO A;  1JNB A;  4LUH A;  2E0X A;  1E7G A;  5GIN A;  1E7H A;  4LUF A;  4TQ1 A;  4N0F D;  4GG2 A;  1UOR A;  3ICX A;  1HA2 A;  1TF0 A;  2BXQ A;  3GQU A;  4GDK B;  2BXE A;  4F5S A;  2DYM A;  5IJ5 A;  3UIV A;  5IIX A;  1HK4 A;  2BXA A;  3NVI A;  1J78 A;  4F5V A;  1E7F A;  3CX9 A;  2K0N A;  4N3Z A;  4L9K A;  2LOQ A;  1BKE A;  2EFC A;  4G03 A;  3BPJ A;  2DG5 A;  4L9Q A;  4W4U B;  4ZC6 A;  4ZUX V;  1MUS A;  4HGM B;  1VZS A;  2BXH A;  2BXI A;  2EFE A;  1BM0 A;  2XMO A;  3MHS B;  4FK5 B;  4LB9 A;  2GUT A;  4PO0 A;  5GHK A;  4N0U D;  5BPK A;  4D7X A;  4FJC B;  2NQO A;  2Z8J A;  3FWB C;  5DBY A;  2ROH A;  3ECP A;  4JK4 A;  1MA9 A;  3MHH B;  4F5T A;  5B5T A;  1MIY A;  3A75 A;  3FWC C;  4S1Y A;  2KBZ A;  3B9L A;  2VUF A;  2BXF A;  2XVQ A;  3V08 A;  1SB0 A;  1E7E A;  2Z8I A;  2BXL A;  4IW2 A;  2QMC A;  3SIV B;  2QHB A;  2XVW A;  5HOZ A;  1MUH A;  1J7E A;  4G04 A;  4BKE A;  2I2Z A;  2VUE A;  2XVV A;  2YDF A;  4I9O A;  4GDL B;  2V36 A;  3LU8 A;  4ZBR A;  4DHX B;  2BXP A;  3LU6 A;  4E99 A;  4TQ0 A;  4LB2 A;  4K2C A;  5IJF A;  2CKX A;  4ZCG A;  3SQJ A;  2XW0 A;  5GIP A;  1IJG A;  1KXP D;  4K71 A;  5D7G A;  4BY9 C;  5IIH A;  2BXD A;  3NVM A;  5ID9 A;  1HK1 A;  3JRY A;  4MBE C;  2LQI A;  3G9K D;  1LOT A; 
#chains in the Genus database with same CATH homology
 2QM6 A;  3KIK A;  3VQI A;  2BXM A;  2BXB A;  1GNJ A;  2XW1 A;  4M70 B;  3WHR A;  3H3A A;  1E78 A;  3GA9 L;  3TDL A;  3V09 A;  2XVU A;  1MIW A;  2E0Y A;  1O9X A;  1N5U A;  2Z8K A;  2EFH A;  4L8U A;  5DQF A;  2OZB B;  3M99 C;  4ZBQ A;  4WA6 B;  4FIP B;  2VDB A;  4EMX A;  5IIU A;  5ID7 A;  2BXN A;  5IFO A;  2I30 A;  1KW2 A;  4ZBK A;  3WHQ A;  2BXK A;  4OTT A;  5GIO A;  1BJ5 A;  1HK5 A;  4IW1 A;  2DYO A;  1MIV A;  4NAW B;  1E7I A;  1LNS A;  4J2V A;  4OTU A;  1VFI A;  2AJE A;  2DBU A;  4Z69 A;  3GQX A;  3FNM A;  2BXG A;  1E7A A;  2BXO A;  3A73 A;  2EFD A;  2OT3 A;  2BXC A;  4OT2 A;  4LA0 A;  3KJL A;  5IJE A;  3NVK A;  4F5U A;  2NNW A;  3PLA A;  3NMU A;  2DBX A;  2DBW A;  3LU7 A;  1HK2 A;  1HK3 A;  3WHS A;  3B9M A;  1FOU A;  2BX8 A;  4HGK A;  4OR0 A;  4Z9O A;  1H9Z A;  1TXU A;  3JQZ A;  1NT2 B;  1AO6 A;  3H37 A;  3SIU B;  3V03 A;  1H5W A;  2XSI A;  1E7B A;  4GDX A;  2JUH A;  1E7C A;  3W1S A;  4G01 A;  1GNI A;  5FUO A;  1JNB A;  4LUH A;  2E0X A;  1E7G A;  5GIN A;  1E7H A;  4LUF A;  4TQ1 A;  4N0F D;  4GG2 A;  1UOR A;  3ICX A;  1HA2 A;  1TF0 A;  2BXQ A;  3GQU A;  4GDK B;  2BXE A;  4F5S A;  2DYM A;  5IJ5 A;  3UIV A;  5IIX A;  1HK4 A;  2BXA A;  3NVI A;  1J78 A;  4F5V A;  1E7F A;  3CX9 A;  4N3Z A;  4L9K A;  2LOQ A;  1BKE A;  2EFC A;  4G03 A;  4L9Q A;  2DG5 A;  4W4U B;  4ZC6 A;  4ZUX V;  4HGM B;  1VZS A;  2BXH A;  2BXI A;  2EFE A;  1BM0 A;  2XMO A;  3MHS B;  4FK5 B;  4LB9 A;  4PO0 A;  5GHK A;  4C31 B;  4N0U D;  5BPK A;  4FJC B;  2NQO A;  2Z8J A;  3FWB C;  5DBY A;  2ROH A;  4JK4 A;  1MA9 A;  3MHH B;  4F5T A;  5B5T A;  1MIY A;  3A75 A;  3FWC C;  4S1Y A;  2KBZ A;  3B9L A;  2VUF A;  2BXF A;  2XVQ A;  3V08 A;  4IW2 A;  1E7E A;  2Z8I A;  2BXL A;  2QMC A;  3SIV B;  2QHB A;  2XVW A;  5HOZ A;  1J7E A;  4G04 A;  4BKE A;  2I2Z A;  2VUE A;  2XVV A;  2YDF A;  4GDL B;  2V36 A;  3LU8 A;  4ZBR A;  4DHX B;  2BXP A;  3LU6 A;  4E99 A;  4TQ0 A;  4LB2 A;  4K2C A;  5IJF A;  2CKX A;  4ZCG A;  3SQJ A;  2XW0 A;  5GIP A;  1IJG A;  1KXP D;  4K71 A;  5D7G A;  4BY9 C;  5IIH A;  2BXD A;  3NVM A;  5ID9 A;  1HK1 A;  3JRY A;  4MBE C;  3G9K D;  1LOT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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