1LOTA

Crystal structure of the complex of actin with vitamin d-binding protein
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
457
structure length
436
Chain Sequence
LERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 A resolution.
pubmed doi rcsb
molecule tags Transport protein, structural protein
molecule keywords Vitamin D-binding protein
total genus 161
structure length 436
sequence length 457
ec nomenclature
pdb deposition date 2002-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
A PF09164 VitD-bind_III Vitamin D binding protein, domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1lotA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1lotA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1lotA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1lotA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1lotA05
2XVVA 2XVQA 1E7CA 2BXPA 1N5UA 2YDFA 4IW1A 4BKEA 1H9ZA 1HK4A 4F5SA 1GNIA 3JQZA 2BXAA 4OR0A 5IIXA 2VDBA 4OT2A 2BXKA 2I2ZA 3CX9A 1J7EA 4HGKA 1KXPD 1O9XA 2BXGA 4PO0A 1HK5A 2VUEA 1HA2A 5DBYA 3V03A 4G03A 2BXNA 3SQJA 4HGMB 3A73A 5IIHA 1BM0A 5FUOA 2XW0A 4L9QA 2BXBA 2BXCA 4EMXA 4E99A 2XVUA 1HK1A 3JRYA 4N0FD 3B9MA 5ID9A 1HK3A 1UORA 1AO6A 1BKEA 2BXMA 2BXEA 2I30A 4LA0A 1BJ5A 5GHKA 2BXOA 2BXFA 3V08A 2BXIA 4F5UA 2VUFA 2BX8A 3LU6A 4J2VA 2BXDA 2XVWA 4Z69A 3B9LA 1TF0A 3LU8A 2XSIA 1E7IA 5IJFA 5IJEA 4LB9A 5ID7A 4JK4A 5IFOA 1MA9A 1E7EA 4S1YA 4F5VA 4LB2A 4K71A 5IJ5A 5IIUA 1E7FA 1J78A 4N0UD 3UIVA 1E7HA 5HOZA 4L9KA 4IW2A 3TDLA 1E7BA 4L8UA 2BXHA 4F5TA 1HK2A 4ZBRA 5DQFA 1GNJA 1LOTA 1E7GA 3LU7A 1E7AA 2XW1A 4ZBQA 3V09A 1KW2A 4LUHA 1E78A 4K2CA 2BXLA 4LUFA 2BXQA 4G04A
chains in the Genus database with same CATH superfamily
1MUSA 1IJGA 1TXUA 2XVVA 2XVQA 1E7CA 2BXPA 2EFCA 5GIOA 1N5UA 2YDFA 4IW1A 4BKEA 1H9ZA 1HK4A 3ECPA 4F5SA 3G9KD 1GNIA 2LOQA 2QMCA 3FWBC 3BPJA 3JQZA 2BXAA 4OR0A 1MIWA 2NQOA 5IIXA 2VDBA 4OT2A 5BPKA 2BXKA 2I2ZA 1LNSA 2V36A 3CX9A 2LQHA 4I9OA 3VQIA 3GQXA 3MHHB 4TQ1A 2EFHA 1J7EA 3WHQA 4HGKA 2Z8KA 1KXPD 1O9XA 2BXGA 4PO0A 4FJCB 1HK5A 5GINA 4BY9C 2VUEA 3GQUA 1HA2A 2EFDA 5DBYA 3M99C 3V03A 3W1SA 2E0YA 3KJLA 2BXNA 4G03A 3SQJA 4HGMB 2QHBA 2DBXA 3A73A 5IIHA 1BM0A 5FUOA 2XW0A 4L9QA 3NMUA 2BXBA 2BXCA 4GG2A 4FK5B 4EMXA 4E99A 2XVUA 1HK1A 3JRYA 3ICXA 3MHSB 2ROHA 3B9MA 1JNBA 4N0FD 5ID9A 1HK3A 1UORA 5GIPA 1AO6A 1BKEA 3NVIA 2BXMA 2BXEA 3NVKA 2I30A 4LA0A 1BJ5A 5GHKA 3NVMA 3H3AA 1NT2B 2AGHB 2BXOA 4ZCGA 4ZUXV 2OZBB 2KWFA 2BXFA 3V08A 5B5TA 4NAWB 2BXIA 4F5UA 2JUHA 3A75A 2AJEA 4Z9OA 2VUFA 4OTUA 2BX8A 3LU6A 3PLAA 4J2VA 2BXDA 2LXTA 2XMOA 2XVWA 4Z69A 3B9LA 1TF0A 3LU8A 4C31B 2XSIA 1E7IA 4GDXA 4N3ZA 4MBEC 1MIVA 5IJFA 5IJEA 4LB9A 2DG5A 4ZC6A 4M70B 2Z8IA 4W4UB 3SIVB 5ID7A 4JK4A 1MUHA 2K0NA 5IFOA 1SB0A 4ZBKA 1MA9A 4OTTA 1E7EA 4S1YA 3FNMA 5D7GA 4F5VA 1MM8A 4GDLB 2DYMA 4LB2A 4K71A 5IJ5A 4D7XA 2DYOA 5IIUA 3SIUB 2LXSA 1KDXA 1E7FA 1J78A 2LQIA 4GDKB 2KBZA 3FWCC 4N0UD 4WA6B 4DHXB 3UIVA 1E7HA 2DBUA 2E0XA 2GUTA 4L9KA 5HOZA 4IW2A 3TDLA 1E7BA 4L8UA 2Z8JA 3KIKA 2QM6A 4FIPB 2BXHA 4G01A 4F5TA 1HK2A 2CKXA 5DQFA 4ZBRA 1GNJA 1FOUA 3WHRA 1LOTA 4TQ0A 1E7GA 3LU7A 2OT3A 1MIYA 4DM0A 3H37A 1E7AA 3WHSA 1H5WA 2DBWA 2NNWA 2XW1A 3GA9L 1KW2A 1VZSA 4ZBQA 3V09A 4LUHA 1VFIA 1E78A 2EFEA 4K2CA 2BXLA 4LUFA 2BXQA 4G04A
chains in the Genus database with same CATH topology
1IJGA 1TXUA 2XVVA 2XVQA 1E7CA 2BXPA 2EFCA 5GIOA 1N5UA 2YDFA 4IW1A 4BKEA 1H9ZA 1HK4A 4F5SA 3G9KD 1GNIA 2LOQA 2QMCA 3FWBC 3JQZA 2BXAA 4OR0A 1MIWA 2NQOA 5IIXA 2VDBA 4OT2A 5BPKA 2BXKA 2I2ZA 1LNSA 2V36A 3CX9A 3VQIA 3GQXA 3MHHB 4TQ1A 1J7EA 2EFHA 3WHQA 4HGKA 2Z8KA 1KXPD 1O9XA 2BXGA 4PO0A 4FJCB 1HK5A 5GINA 4BY9C 2VUEA 3GQUA 1HA2A 2EFDA 5DBYA 3M99C 3V03A 3W1SA 2E0YA 3KJLA 2BXNA 4G03A 3SQJA 4HGMB 2QHBA 2DBXA 3A73A 5IIHA 1BM0A 5FUOA 2XW0A 4L9QA 3NMUA 2BXBA 2BXCA 4GG2A 4FK5B 4EMXA 4E99A 2XVUA 1HK1A 3JRYA 3ICXA 3MHSB 2ROHA 3B9MA 1JNBA 4N0FD 5ID9A 1HK3A 1UORA 5GIPA 1AO6A 1BKEA 3NVIA 2BXMA 2BXEA 3NVKA 2I30A 4LA0A 1BJ5A 5GHKA 3NVMA 3H3AA 1NT2B 2BXOA 4ZCGA 4ZUXV 2OZBB 2BXFA 3V08A 5B5TA 4NAWB 2BXIA 4F5UA 2JUHA 3A75A 2AJEA 4Z9OA 2VUFA 4OTUA 2BX8A 3LU6A 3PLAA 4J2VA 2BXDA 2XMOA 2XVWA 4Z69A 3B9LA 1TF0A 3LU8A 4C31B 2XSIA 1E7IA 4GDXA 4N3ZA 4MBEC 1MIVA 5IJFA 5IJEA 4LB9A 2DG5A 4ZC6A 4M70B 2Z8IA 4W4UB 3SIVB 5ID7A 4JK4A 5IFOA 4ZBKA 1MA9A 4OTTA 1E7EA 4S1YA 3FNMA 5D7GA 4F5VA 4GDLB 2DYMA 4LB2A 4K71A 5IJ5A 2DYOA 5IIUA 3SIUB 1E7FA 1J78A 4GDKB 2KBZA 3FWCC 4N0UD 4WA6B 4DHXB 3UIVA 1E7HA 2DBUA 2E0XA 4L9KA 5HOZA 4IW2A 3TDLA 1E7BA 4L8UA 2Z8JA 3KIKA 2QM6A 4FIPB 2BXHA 4G01A 4F5TA 1HK2A 2CKXA 5DQFA 4ZBRA 1GNJA 1FOUA 3WHRA 1LOTA 4TQ0A 1E7GA 3LU7A 2OT3A 1MIYA 3H37A 1E7AA 3WHSA 1H5WA 2DBWA 2NNWA 2XW1A 3GA9L 1KW2A 1VZSA 4ZBQA 3V09A 4LUHA 1VFIA 1E78A 2EFEA 4K2CA 2BXLA 4LUFA 2BXQA 4G04A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XVV A;  2XVQ A;  1E7C A;  2BXP A;  1N5U A;  2YDF A;  4IW1 A;  4BKE A;  1H9Z A;  1HK4 A;  4F5S A;  1GNI A;  3JQZ A;  2BXA A;  4OR0 A;  5IIX A;  2VDB A;  4OT2 A;  2BXK A;  2I2Z A;  3CX9 A;  1J7E A;  4HGK A;  1KXP D;  1O9X A;  2BXG A;  4PO0 A;  1HK5 A;  2VUE A;  1HA2 A;  5DBY A;  3V03 A;  4G03 A;  2BXN A;  3SQJ A;  4HGM B;  3A73 A;  5IIH A;  1BM0 A;  5FUO A;  2XW0 A;  4L9Q A;  2BXB A;  2BXC A;  4EMX A;  4E99 A;  2XVU A;  1HK1 A;  3JRY A;  4N0F D;  3B9M A;  5ID9 A;  1HK3 A;  1UOR A;  1AO6 A;  1BKE A;  2BXM A;  2BXE A;  2I30 A;  4LA0 A;  1BJ5 A;  5GHK A;  2BXO A;  2BXF A;  3V08 A;  2BXI A;  4F5U A;  2VUF A;  2BX8 A;  3LU6 A;  4J2V A;  2BXD A;  2XVW A;  4Z69 A;  3B9L A;  1TF0 A;  3LU8 A;  2XSI A;  1E7I A;  5IJF A;  5IJE A;  4LB9 A;  5ID7 A;  4JK4 A;  5IFO A;  1MA9 A;  1E7E A;  4S1Y A;  4F5V A;  4LB2 A;  4K71 A;  5IJ5 A;  5IIU A;  1E7F A;  1J78 A;  4N0U D;  3UIV A;  1E7H A;  5HOZ A;  4L9K A;  4IW2 A;  3TDL A;  1E7B A;  4L8U A;  2BXH A;  4F5T A;  1HK2 A;  4ZBR A;  5DQF A;  1GNJ A;  1LOT A;  1E7G A;  3LU7 A;  1E7A A;  2XW1 A;  4ZBQ A;  3V09 A;  1KW2 A;  4LUH A;  1E78 A;  4K2C A;  2BXL A;  4LUF A;  2BXQ A;  4G04 A; 
#chains in the Genus database with same CATH topology
 1MUS A;  1IJG A;  1TXU A;  2XVV A;  2XVQ A;  1E7C A;  2BXP A;  2EFC A;  5GIO A;  1N5U A;  2YDF A;  4IW1 A;  4BKE A;  1H9Z A;  1HK4 A;  3ECP A;  4F5S A;  3G9K D;  1GNI A;  2LOQ A;  2QMC A;  3FWB C;  3BPJ A;  3JQZ A;  2BXA A;  4OR0 A;  1MIW A;  2NQO A;  5IIX A;  2VDB A;  4OT2 A;  5BPK A;  2BXK A;  2I2Z A;  1LNS A;  2V36 A;  3CX9 A;  2LQH A;  4I9O A;  3VQI A;  3GQX A;  3MHH B;  4TQ1 A;  2EFH A;  1J7E A;  3WHQ A;  4HGK A;  2Z8K A;  1KXP D;  1O9X A;  2BXG A;  4PO0 A;  4FJC B;  1HK5 A;  5GIN A;  4BY9 C;  2VUE A;  3GQU A;  1HA2 A;  2EFD A;  5DBY A;  3M99 C;  3V03 A;  3W1S A;  2E0Y A;  3KJL A;  2BXN A;  4G03 A;  3SQJ A;  4HGM B;  2QHB A;  2DBX A;  3A73 A;  5IIH A;  1BM0 A;  5FUO A;  2XW0 A;  4L9Q A;  3NMU A;  2BXB A;  2BXC A;  4GG2 A;  4FK5 B;  4EMX A;  4E99 A;  2XVU A;  1HK1 A;  3JRY A;  3ICX A;  3MHS B;  2ROH A;  3B9M A;  1JNB A;  4N0F D;  5ID9 A;  1HK3 A;  1UOR A;  5GIP A;  1AO6 A;  1BKE A;  3NVI A;  2BXM A;  2BXE A;  3NVK A;  2I30 A;  4LA0 A;  1BJ5 A;  5GHK A;  3NVM A;  3H3A A;  1NT2 B;  2AGH B;  2BXO A;  4ZCG A;  4ZUX V;  2OZB B;  2KWF A;  2BXF A;  3V08 A;  5B5T A;  4NAW B;  2BXI A;  4F5U A;  2JUH A;  3A75 A;  2AJE A;  4Z9O A;  2VUF A;  4OTU A;  2BX8 A;  3LU6 A;  3PLA A;  4J2V A;  2BXD A;  2LXT A;  2XMO A;  2XVW A;  4Z69 A;  3B9L A;  1TF0 A;  3LU8 A;  4C31 B;  2XSI A;  1E7I A;  4GDX A;  4N3Z A;  4MBE C;  1MIV A;  5IJF A;  5IJE A;  4LB9 A;  2DG5 A;  4ZC6 A;  4M70 B;  2Z8I A;  4W4U B;  3SIV B;  5ID7 A;  4JK4 A;  1MUH A;  2K0N A;  5IFO A;  1SB0 A;  4ZBK A;  1MA9 A;  4OTT A;  1E7E A;  4S1Y A;  3FNM A;  5D7G A;  4F5V A;  1MM8 A;  4GDL B;  2DYM A;  4LB2 A;  4K71 A;  5IJ5 A;  4D7X A;  2DYO A;  5IIU A;  3SIU B;  2LXS A;  1KDX A;  1E7F A;  1J78 A;  2LQI A;  4GDK B;  2KBZ A;  3FWC C;  4N0U D;  4WA6 B;  4DHX B;  3UIV A;  1E7H A;  2DBU A;  2E0X A;  2GUT A;  4L9K A;  5HOZ A;  4IW2 A;  3TDL A;  1E7B A;  4L8U A;  2Z8J A;  3KIK A;  2QM6 A;  4FIP B;  2BXH A;  4G01 A;  4F5T A;  1HK2 A;  2CKX A;  5DQF A;  4ZBR A;  1GNJ A;  1FOU A;  3WHR A;  1LOT A;  4TQ0 A;  1E7G A;  3LU7 A;  2OT3 A;  1MIY A;  4DM0 A;  3H37 A;  1E7A A;  3WHS A;  1H5W A;  2DBW A;  2NNW A;  2XW1 A;  3GA9 L;  1KW2 A;  1VZS A;  4ZBQ A;  3V09 A;  4LUH A;  1VFI A;  1E78 A;  2EFE A;  4K2C A;  2BXL A;  4LUF A;  2BXQ A;  4G04 A; 
#chains in the Genus database with same CATH homology
 1IJG A;  1TXU A;  2XVV A;  2XVQ A;  1E7C A;  2BXP A;  2EFC A;  5GIO A;  1N5U A;  2YDF A;  4IW1 A;  4BKE A;  1H9Z A;  1HK4 A;  4F5S A;  3G9K D;  1GNI A;  2LOQ A;  2QMC A;  3FWB C;  3JQZ A;  2BXA A;  4OR0 A;  1MIW A;  2NQO A;  5IIX A;  2VDB A;  4OT2 A;  5BPK A;  2BXK A;  2I2Z A;  1LNS A;  2V36 A;  3CX9 A;  3VQI A;  3GQX A;  3MHH B;  4TQ1 A;  1J7E A;  2EFH A;  3WHQ A;  4HGK A;  2Z8K A;  1KXP D;  1O9X A;  2BXG A;  4PO0 A;  4FJC B;  1HK5 A;  5GIN A;  4BY9 C;  2VUE A;  3GQU A;  1HA2 A;  2EFD A;  5DBY A;  3M99 C;  3V03 A;  3W1S A;  2E0Y A;  3KJL A;  2BXN A;  4G03 A;  3SQJ A;  4HGM B;  2QHB A;  2DBX A;  3A73 A;  5IIH A;  1BM0 A;  5FUO A;  2XW0 A;  4L9Q A;  3NMU A;  2BXB A;  2BXC A;  4GG2 A;  4FK5 B;  4EMX A;  4E99 A;  2XVU A;  1HK1 A;  3JRY A;  3ICX A;  3MHS B;  2ROH A;  3B9M A;  1JNB A;  4N0F D;  5ID9 A;  1HK3 A;  1UOR A;  5GIP A;  1AO6 A;  1BKE A;  3NVI A;  2BXM A;  2BXE A;  3NVK A;  2I30 A;  4LA0 A;  1BJ5 A;  5GHK A;  3NVM A;  3H3A A;  1NT2 B;  2BXO A;  4ZCG A;  4ZUX V;  2OZB B;  2BXF A;  3V08 A;  5B5T A;  4NAW B;  2BXI A;  4F5U A;  2JUH A;  3A75 A;  2AJE A;  4Z9O A;  2VUF A;  4OTU A;  2BX8 A;  3LU6 A;  3PLA A;  4J2V A;  2BXD A;  2XMO A;  2XVW A;  4Z69 A;  3B9L A;  1TF0 A;  3LU8 A;  4C31 B;  2XSI A;  1E7I A;  4GDX A;  4N3Z A;  4MBE C;  1MIV A;  5IJF A;  5IJE A;  4LB9 A;  2DG5 A;  4ZC6 A;  4M70 B;  2Z8I A;  4W4U B;  3SIV B;  5ID7 A;  4JK4 A;  5IFO A;  4ZBK A;  1MA9 A;  4OTT A;  1E7E A;  4S1Y A;  3FNM A;  5D7G A;  4F5V A;  4GDL B;  2DYM A;  4LB2 A;  4K71 A;  5IJ5 A;  2DYO A;  5IIU A;  3SIU B;  1E7F A;  1J78 A;  4GDK B;  2KBZ A;  3FWC C;  4N0U D;  4WA6 B;  4DHX B;  3UIV A;  1E7H A;  2DBU A;  2E0X A;  4L9K A;  5HOZ A;  4IW2 A;  3TDL A;  1E7B A;  4L8U A;  2Z8J A;  3KIK A;  2QM6 A;  4FIP B;  2BXH A;  4G01 A;  4F5T A;  1HK2 A;  2CKX A;  5DQF A;  4ZBR A;  1GNJ A;  1FOU A;  3WHR A;  1LOT A;  4TQ0 A;  1E7G A;  3LU7 A;  2OT3 A;  1MIY A;  3H37 A;  1E7A A;  3WHS A;  1H5W A;  2DBW A;  2NNW A;  2XW1 A;  3GA9 L;  1KW2 A;  1VZS A;  4ZBQ A;  3V09 A;  4LUH A;  1VFI A;  1E78 A;  2EFE A;  4K2C A;  2BXL A;  4LUF A;  2BXQ A;  4G04 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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