1XQOA

Crystal structure of native pa-agog, 8-oxoguanine dna glycosylase from pyrobaculum aerophilum
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
253
structure length
253
Chain Sequence
AAESQLKRVIETLRRLGIEEVLKLERRDPQYRAVCNVVKRHGETVGSRLAMLNALISYRLTGKGEEHWEYFGKYFSQLEVIDLCRDFLKYIETSPFLKIGVEARKKRALKACDYVPNLEDLGLTLRQLSHIVGARREQKTLVFTIKILNYAYMCSRGVNRVLPFDIPIPVDYRVARLTWCAGLIDFPPEEALRRYEAVQKIWDAVARETGIPPLHLDTLLWLAGRAVLYGENLHGVPKEVIALFQWRGGCRPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
pubmed doi rcsb
molecule tags Lyase
source organism Pyrobaculum aerophilum
molecule keywords 8-oxoguanine DNA glycosylase
total genus 98
structure length 253
sequence length 253
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09171 AGOG N-glycosylase/DNA lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1xqoA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1xqoA01
1MUDA 1MUYA 4YOQA 5DPKA 3F0ZA 4B24A 4AI5A 3FSPA 1NKUA 4HSBA 4AI4A 4OFEA 3KTUA 4EW4A 4DK9A 1MUNA 1KG6A 1M3HA 3FHFA 2JHJA 3F10A 5KN8A 1WEFA 1P59A 2I5WA 2NOBA 4EA4A 1PU7A 3CWUA 1YQRA 3OGDA 4OFAA 4PIIA 4EW0A 4E9FA 1LWWA 1WEGA 2ABKA 1N3CA 4YPRA 4OFHA 1P7MA 1PVSA 1KG4A 1M3QA 4E9HA 1N3AA 1KG7A 2JHNA 4EVVA 4E9EA 4YPHA 4B21A 1XQOA 3G0QA 5KN9A 3CWAA 4EA5A 2NOLA 3CVTA 1KG5A 4B22A 2OFKA 1KG2A 2NOIA 3N0UA 1RRQA 2XHIA 2YG9A 1ORPA 1KEAA 4EJYA 1WEIA 2NOEA 4E9GA 1XQPA 5AN4A 1RRSA 3IHOA 2NOZA 1MPGA 3CVSA 1N39A 1ORNA 1PU6A 1XG7A 1KG3A 3CW7A 1KO9A 3CWSA 5CHZA 1LWVA 1EBMA 3KNTA 1YQMA 3N5NX 3CWTA 1YQLA 1YQKA 2JG6A 3OH9A 1HU0A 2H56A 4UNFA 1DIZA 2NOHA 1LMZA 2YG8A 3I0XA 1LWYA 1FN7A 1PU8A 3S6IA 3FHGA 4AIAA 4B23A 3OH6A 1VRLA 3D4VA 2OFIA 4EJZA 1KQJA 2NOFA 1NGNA 3IH7A 3I0WA 4UOBA
chains in the Genus database with same CATH superfamily
1MUDA 1MUYA 3NNQA 4YOQA 3F0ZA 4B24A 3L2RA 4AI5A 5DPKA 3FSPA 3S3MA 1NKUA 4HSBA 4AI4A 4OFEA 3OYGA 3KTUA 4EW4A 1MUNA 4DK9A 1KG6A 1M3HA 3FHFA 2JHJA 5FRNA 3F10A 5KN8A 3S3OA 3OS2A 3OYHA 1WEFA 1P59A 2I5WA 2NOBA 3OS0A 5FRMA 4EA4A 1PU7A 3CWUA 1YQRA 3OGDA 4OFAA 4NZGA 4PIIA 4EW0A 4E9FA 4E7JA 4ZTJA 3LCNA 1LWWA 1WEGA 2ABKA 1N3CA 4YPRA 5FROA 4OFHA 3OYMA 3OY9A 1P7MA 1PVSA 1KG4A 3OYJA 1M3QA 4E9HA 1N3AA 1KG7A 2JHNA 3L2UA 4EVVA 4E9EA 3VW4A 4E7HA 4YPHA 4E7IA 4B21A 1XQOA 3G0QA 5KN9A 3CWAA 4EA5A 2NOLA 4BE2A 3CVTA 1KG5A 4B22A 2OFKA 1KG2A 2NOIA 3N0UA 1RRQA 2XHIA 3OYBA 2YG9A 1ORPA 3OYEA 1KEAA 3S3NA 4EJYA 1WEIA 2NOEA 4E9GA 3OYCA 1XQPA 5AN4A 1RRSA 3OYKA 3IHOA 3OYFA 2NOZA 1MPGA 3CVSA 3OS1A 1N39A 1ORNA 3R2XC 2W03A 4BDZA 1PU6A 1XG7A 1KG3A 3CW7A 1KO9A 3CWSA 2V75A 2JPSA 3OYDA 5CHZA 1LWVA 1EBMA 3KNTA 3OYNA 2W04A 3N5NX 1YQMA 3CWTA 1YQLA 1YQKA 2JG6A 3OH9A 3OYAA 1HU0A 2H56A 4UNFA 1DIZA 2NOHA 3L2WA 4E7KA 1LMZA 3L2QA 3L2VA 2YG8A 4IKFA 3I0XA 3OYLA 1LWYA 1FN7A 1PU8A 4E7LA 3S6IA 4ZTFA 3FHGA 4BE1A 4AIAA 4B23A 3OH6A 1VRLA 3D4VA 4BE0A 1U84A 2OFIA 4EJZA 1KQJA 3OYIA 2NOFA 1NGNA 4BACA 4BDYA 3IH7A 3I0WA 4UOBA
chains in the Genus database with same CATH topology
1MUDA 1MUYA 4YOQA 5DPKA 3F0ZA 4B24A 4AI5A 3FSPA 1NKUA 4HSBA 4AI4A 4OFEA 3KTUA 4EW4A 4DK9A 1MUNA 1KG6A 1M3HA 3FHFA 2JHJA 3F10A 5KN8A 1WEFA 1P59A 2I5WA 2NOBA 4EA4A 1PU7A 3CWUA 1YQRA 3OGDA 4OFAA 4PIIA 4EW0A 4E9FA 1LWWA 1WEGA 2ABKA 1N3CA 4YPRA 4OFHA 1P7MA 1PVSA 1KG4A 1M3QA 4E9HA 1N3AA 1KG7A 2JHNA 4EVVA 4E9EA 4YPHA 4B21A 1XQOA 3G0QA 5KN9A 3CWAA 4EA5A 2NOLA 3CVTA 1KG5A 4B22A 2OFKA 1KG2A 2NOIA 3N0UA 1RRQA 2XHIA 2YG9A 1ORPA 1KEAA 4EJYA 1WEIA 2NOEA 4E9GA 1XQPA 5AN4A 1RRSA 3IHOA 2NOZA 1MPGA 3CVSA 1N39A 1ORNA 1PU6A 1XG7A 1KG3A 3CW7A 1KO9A 3CWSA 5CHZA 1LWVA 1EBMA 3KNTA 1YQMA 3N5NX 3CWTA 1YQLA 1YQKA 2JG6A 3OH9A 1HU0A 2H56A 4UNFA 1DIZA 2NOHA 1LMZA 2YG8A 3I0XA 1LWYA 1FN7A 1PU8A 3S6IA 3FHGA 4AIAA 4B23A 3OH6A 1VRLA 3D4VA 2OFIA 4EJZA 1KQJA 2NOFA 1NGNA 3IH7A 3I0WA 4UOBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MUD A;  1MUY A;  4YOQ A;  5DPK A;  3F0Z A;  4B24 A;  4AI5 A;  3FSP A;  1NKU A;  4HSB A;  4AI4 A;  4OFE A;  3KTU A;  4EW4 A;  4DK9 A;  1MUN A;  1KG6 A;  1M3H A;  3FHF A;  2JHJ A;  3F10 A;  5KN8 A;  1WEF A;  1P59 A;  2I5W A;  2NOB A;  4EA4 A;  1PU7 A;  3CWU A;  1YQR A;  3OGD A;  4OFA A;  4PII A;  4EW0 A;  4E9F A;  1LWW A;  1WEG A;  2ABK A;  1N3C A;  4YPR A;  4OFH A;  1P7M A;  1PVS A;  1KG4 A;  1M3Q A;  4E9H A;  1N3A A;  1KG7 A;  2JHN A;  4EVV A;  4E9E A;  4YPH A;  4B21 A;  1XQO A;  3G0Q A;  5KN9 A;  3CWA A;  4EA5 A;  2NOL A;  3CVT A;  1KG5 A;  4B22 A;  2OFK A;  1KG2 A;  2NOI A;  3N0U A;  1RRQ A;  2XHI A;  2YG9 A;  1ORP A;  1KEA A;  4EJY A;  1WEI A;  2NOE A;  4E9G A;  1XQP A;  5AN4 A;  1RRS A;  3IHO A;  2NOZ A;  1MPG A;  3CVS A;  1N39 A;  1ORN A;  1PU6 A;  1XG7 A;  1KG3 A;  3CW7 A;  1KO9 A;  3CWS A;  5CHZ A;  1LWV A;  1EBM A;  3KNT A;  1YQM A;  3N5N X;  3CWT A;  1YQL A;  1YQK A;  2JG6 A;  3OH9 A;  1HU0 A;  2H56 A;  4UNF A;  1DIZ A;  2NOH A;  1LMZ A;  2YG8 A;  3I0X A;  1LWY A;  1FN7 A;  1PU8 A;  3S6I A;  3FHG A;  4AIA A;  4B23 A;  3OH6 A;  1VRL A;  3D4V A;  2OFI A;  4EJZ A;  1KQJ A;  2NOF A;  1NGN A;  3IH7 A;  3I0W A;  4UOB A; 
#chains in the Genus database with same CATH topology
 1MUD A;  1MUY A;  3NNQ A;  4YOQ A;  3F0Z A;  4B24 A;  3L2R A;  4AI5 A;  5DPK A;  3FSP A;  3S3M A;  1NKU A;  4HSB A;  4AI4 A;  4OFE A;  3OYG A;  3KTU A;  4EW4 A;  1MUN A;  4DK9 A;  1KG6 A;  1M3H A;  3FHF A;  2JHJ A;  5FRN A;  3F10 A;  5KN8 A;  3S3O A;  3OS2 A;  3OYH A;  1WEF A;  1P59 A;  2I5W A;  2NOB A;  3OS0 A;  5FRM A;  4EA4 A;  1PU7 A;  3CWU A;  1YQR A;  3OGD A;  4OFA A;  4NZG A;  4PII A;  4EW0 A;  4E9F A;  4E7J A;  4ZTJ A;  3LCN A;  1LWW A;  1WEG A;  2ABK A;  1N3C A;  4YPR A;  5FRO A;  4OFH A;  3OYM A;  3OY9 A;  1P7M A;  1PVS A;  1KG4 A;  3OYJ A;  1M3Q A;  4E9H A;  1N3A A;  1KG7 A;  2JHN A;  3L2U A;  4EVV A;  4E9E A;  3VW4 A;  4E7H A;  4YPH A;  4E7I A;  4B21 A;  1XQO A;  3G0Q A;  5KN9 A;  3CWA A;  4EA5 A;  2NOL A;  4BE2 A;  3CVT A;  1KG5 A;  4B22 A;  2OFK A;  1KG2 A;  2NOI A;  3N0U A;  1RRQ A;  2XHI A;  3OYB A;  2YG9 A;  1ORP A;  3OYE A;  1KEA A;  3S3N A;  4EJY A;  1WEI A;  2NOE A;  4E9G A;  3OYC A;  1XQP A;  5AN4 A;  1RRS A;  3OYK A;  3IHO A;  3OYF A;  2NOZ A;  1MPG A;  3CVS A;  3OS1 A;  1N39 A;  1ORN A;  3R2X C;  2W03 A;  4BDZ A;  1PU6 A;  1XG7 A;  1KG3 A;  3CW7 A;  1KO9 A;  3CWS A;  2V75 A;  2JPS A;  3OYD A;  5CHZ A;  1LWV A;  1EBM A;  3KNT A;  3OYN A;  2W04 A;  3N5N X;  1YQM A;  3CWT A;  1YQL A;  1YQK A;  2JG6 A;  3OH9 A;  3OYA A;  1HU0 A;  2H56 A;  4UNF A;  1DIZ A;  2NOH A;  3L2W A;  4E7K A;  1LMZ A;  3L2Q A;  3L2V A;  2YG8 A;  4IKF A;  3I0X A;  3OYL A;  1LWY A;  1FN7 A;  1PU8 A;  4E7L A;  3S6I A;  4ZTF A;  3FHG A;  4BE1 A;  4AIA A;  4B23 A;  3OH6 A;  1VRL A;  3D4V A;  4BE0 A;  1U84 A;  2OFI A;  4EJZ A;  1KQJ A;  3OYI A;  2NOF A;  1NGN A;  4BAC A;  4BDY A;  3IH7 A;  3I0W A;  4UOB A; 
#chains in the Genus database with same CATH homology
 1MUD A;  1MUY A;  4YOQ A;  5DPK A;  3F0Z A;  4B24 A;  4AI5 A;  3FSP A;  1NKU A;  4HSB A;  4AI4 A;  4OFE A;  3KTU A;  4EW4 A;  4DK9 A;  1MUN A;  1KG6 A;  1M3H A;  3FHF A;  2JHJ A;  3F10 A;  5KN8 A;  1WEF A;  1P59 A;  2I5W A;  2NOB A;  4EA4 A;  1PU7 A;  3CWU A;  1YQR A;  3OGD A;  4OFA A;  4PII A;  4EW0 A;  4E9F A;  1LWW A;  1WEG A;  2ABK A;  1N3C A;  4YPR A;  4OFH A;  1P7M A;  1PVS A;  1KG4 A;  1M3Q A;  4E9H A;  1N3A A;  1KG7 A;  2JHN A;  4EVV A;  4E9E A;  4YPH A;  4B21 A;  1XQO A;  3G0Q A;  5KN9 A;  3CWA A;  4EA5 A;  2NOL A;  3CVT A;  1KG5 A;  4B22 A;  2OFK A;  1KG2 A;  2NOI A;  3N0U A;  1RRQ A;  2XHI A;  2YG9 A;  1ORP A;  1KEA A;  4EJY A;  1WEI A;  2NOE A;  4E9G A;  1XQP A;  5AN4 A;  1RRS A;  3IHO A;  2NOZ A;  1MPG A;  3CVS A;  1N39 A;  1ORN A;  1PU6 A;  1XG7 A;  1KG3 A;  3CW7 A;  1KO9 A;  3CWS A;  5CHZ A;  1LWV A;  1EBM A;  3KNT A;  1YQM A;  3N5N X;  3CWT A;  1YQL A;  1YQK A;  2JG6 A;  3OH9 A;  1HU0 A;  2H56 A;  4UNF A;  1DIZ A;  2NOH A;  1LMZ A;  2YG8 A;  3I0X A;  1LWY A;  1FN7 A;  1PU8 A;  3S6I A;  3FHG A;  4AIA A;  4B23 A;  3OH6 A;  1VRL A;  3D4V A;  2OFI A;  4EJZ A;  1KQJ A;  2NOF A;  1NGN A;  3IH7 A;  3I0W A;  4UOB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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