1XQPA

Crystal structure of 8-oxoguanosine complexed pa-agog, 8-oxoguanine dna glycosylase from pyrobaculum aerophilum
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
252
structure length
252
Chain Sequence
AESQLKRVIETLRRLGIEEVLKLERRDPQYRAVCNVVKRHGETVGSRLAMLNALISYRLTGKGEEHWEYFGKYFSQLEVIDLCRDFLKYIETSPFLKIGVEARKKRALKACDYVPNLEDLGLTLRQLSHIVGARREQKTLVFTIKILNYAYMCSRGVNRVLPFDIPIPVDYRVARLTWCAGLIDFPPEEALRRYEAVQKIWDAVARETGIPPLHLDTLLWLAGRAVLYGENLHGVPKEVIALFQWRGGCRPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
pubmed doi rcsb
molecule tags Lyase
source organism Pyrobaculum aerophilum
molecule keywords 8-oxoguanine DNA glycosylase
total genus 95
structure length 252
sequence length 252
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09171 AGOG N-glycosylase/DNA lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1xqpA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1xqpA01
1LMZA 4OFEA 3S6IA 5DPKA 2NOFA 3OH6A 3FHFA 4AIAA 3FHGA 1LWWA 3G0QA 1LWYA 1KQJA 4YPRA 4EVVA 3F10A 1RRQA 1KEAA 1XQPA 1MUYA 2JHJA 3CWSA 1P59A 3N0UA 4E9EA 3F0ZA 2JG6A 4B23A 5KN8A 4E9HA 1KG7A 3IHOA 1LWVA 4UNFA 3CWTA 1HU0A 1N39A 1NKUA 1RRSA 4EJYA 1KG3A 1PVSA 5KN9A 5AN4A 2OFKA 1YQLA 3CVSA 4EW0A 1M3QA 4AI4A 1ORNA 2I5WA 3D4VA 1FN7A 1WEFA 1KG2A 1N3AA 4PIIA 1PU6A 3KNTA 3CW7A 2ABKA 1YQKA 3OH9A 1DIZA 2NOBA 4YPHA 4YOQA 1KG4A 1KO9A 3N5NX 3KTUA 1PU8A 1VRLA 4OFAA 5CHZA 4EW4A 1YQMA 1M3HA 3CWAA 1P7MA 4E9FA 2NOIA 2XHIA 3CVTA 4EA5A 3I0WA 3IH7A 4AI5A 1MUDA 1WEGA 1XQOA 4OFHA 4DK9A 1MUNA 1ORPA 1KG6A 1KG5A 4B24A 4HSBA 2NOHA 1YQRA 2NOLA 2YG8A 1PU7A 1EBMA 3FSPA 1MPGA 3CWUA 3OGDA 4E9GA 2NOEA 4EJZA 4B22A 4B21A 2H56A 1XG7A 4UOBA 2NOZA 3I0XA 1WEIA 2OFIA 2YG9A 2JHNA 1N3CA 4EA4A 1NGNA
chains in the Genus database with same CATH superfamily
1LMZA 4OFEA 3S6IA 4BDYA 5DPKA 2NOFA 3OH6A 3S3OA 3FHFA 4AIAA 3FHGA 1LWWA 3G0QA 1LWYA 3OYDA 1KQJA 4YPRA 4IKFA 4BDZA 3S3NA 3OYJA 4EVVA 3F10A 1RRQA 1KEAA 4BE2A 1XQPA 5FROA 3L2UA 3OYHA 1MUYA 4ZTFA 2JHJA 4E7KA 4E7LA 3CWSA 1P59A 3N0UA 2W04A 4E9EA 4BE0A 3F0ZA 2JG6A 4BE1A 4B23A 5KN8A 4BACA 4E9HA 3L2WA 1KG7A 3OY9A 3IHOA 1LWVA 3S3MA 4UNFA 3CWTA 1HU0A 1N39A 1NKUA 1RRSA 4EJYA 1KG3A 1PVSA 5KN9A 5AN4A 4ZTJA 2OFKA 1YQLA 3CVSA 4EW0A 1M3QA 1U84A 4AI4A 3OYKA 1ORNA 3OYGA 2I5WA 3D4VA 1FN7A 1WEFA 4E7JA 1KG2A 1N3AA 4PIIA 3OYEA 1PU6A 3KNTA 5FRNA 3CW7A 2ABKA 1YQKA 3OH9A 1DIZA 3OYMA 2NOBA 3OS0A 4YPHA 3OYIA 4E7HA 4YOQA 1KG4A 3NNQA 1KO9A 3N5NX 3VW4A 3KTUA 1PU8A 1VRLA 4OFAA 4NZGA 3LCNA 3R2XC 3OYLA 5CHZA 4EW4A 1YQMA 1M3HA 3OS1A 3L2RA 3CWAA 1P7MA 4E9FA 2NOIA 2XHIA 3CVTA 4EA5A 3L2QA 3I0WA 3IH7A 2JPSA 4AI5A 1MUDA 3OS2A 1WEGA 1XQOA 4OFHA 4DK9A 3OYBA 4E7IA 1MUNA 1ORPA 1KG6A 1KG5A 4B24A 4HSBA 2NOHA 1YQRA 2NOLA 2YG8A 1PU7A 1EBMA 2V75A 5FRMA 3OYFA 3FSPA 1MPGA 3CWUA 3OGDA 4E9GA 2NOEA 4EJZA 4B22A 4B21A 2H56A 3OYAA 1XG7A 4UOBA 2NOZA 3I0XA 1WEIA 2OFIA 3OYCA 2YG9A 3L2VA 2JHNA 2W03A 1N3CA 3OYNA 4EA4A 1NGNA
chains in the Genus database with same CATH topology
1LMZA 4OFEA 3S6IA 5DPKA 2NOFA 3OH6A 3FHFA 4AIAA 3FHGA 1LWWA 3G0QA 1LWYA 1KQJA 4YPRA 4EVVA 3F10A 1RRQA 1KEAA 1XQPA 1MUYA 2JHJA 3CWSA 1P59A 3N0UA 4E9EA 3F0ZA 2JG6A 4B23A 5KN8A 4E9HA 1KG7A 3IHOA 1LWVA 4UNFA 3CWTA 1HU0A 1N39A 1NKUA 1RRSA 4EJYA 1KG3A 1PVSA 5KN9A 5AN4A 2OFKA 1YQLA 3CVSA 4EW0A 1M3QA 4AI4A 1ORNA 2I5WA 3D4VA 1FN7A 1WEFA 1KG2A 1N3AA 4PIIA 1PU6A 3KNTA 3CW7A 2ABKA 1YQKA 3OH9A 1DIZA 2NOBA 4YPHA 4YOQA 1KG4A 1KO9A 3N5NX 3KTUA 1PU8A 1VRLA 4OFAA 5CHZA 4EW4A 1YQMA 1M3HA 3CWAA 1P7MA 4E9FA 2NOIA 2XHIA 3CVTA 4EA5A 3I0WA 3IH7A 4AI5A 1MUDA 1WEGA 1XQOA 4OFHA 4DK9A 1MUNA 1ORPA 1KG6A 1KG5A 4B24A 4HSBA 2NOHA 1YQRA 2NOLA 2YG8A 1PU7A 1EBMA 3FSPA 1MPGA 3CWUA 3OGDA 4E9GA 2NOEA 4EJZA 4B22A 4B21A 2H56A 1XG7A 4UOBA 2NOZA 3I0XA 1WEIA 2OFIA 2YG9A 2JHNA 1N3CA 4EA4A 1NGNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LMZ A;  4OFE A;  3S6I A;  5DPK A;  2NOF A;  3OH6 A;  3FHF A;  4AIA A;  3FHG A;  1LWW A;  3G0Q A;  1LWY A;  1KQJ A;  4YPR A;  4EVV A;  3F10 A;  1RRQ A;  1KEA A;  1XQP A;  1MUY A;  2JHJ A;  3CWS A;  1P59 A;  3N0U A;  4E9E A;  3F0Z A;  2JG6 A;  4B23 A;  5KN8 A;  4E9H A;  1KG7 A;  3IHO A;  1LWV A;  4UNF A;  3CWT A;  1HU0 A;  1N39 A;  1NKU A;  1RRS A;  4EJY A;  1KG3 A;  1PVS A;  5KN9 A;  5AN4 A;  2OFK A;  1YQL A;  3CVS A;  4EW0 A;  1M3Q A;  4AI4 A;  1ORN A;  2I5W A;  3D4V A;  1FN7 A;  1WEF A;  1KG2 A;  1N3A A;  4PII A;  1PU6 A;  3KNT A;  3CW7 A;  2ABK A;  1YQK A;  3OH9 A;  1DIZ A;  2NOB A;  4YPH A;  4YOQ A;  1KG4 A;  1KO9 A;  3N5N X;  3KTU A;  1PU8 A;  1VRL A;  4OFA A;  5CHZ A;  4EW4 A;  1YQM A;  1M3H A;  3CWA A;  1P7M A;  4E9F A;  2NOI A;  2XHI A;  3CVT A;  4EA5 A;  3I0W A;  3IH7 A;  4AI5 A;  1MUD A;  1WEG A;  1XQO A;  4OFH A;  4DK9 A;  1MUN A;  1ORP A;  1KG6 A;  1KG5 A;  4B24 A;  4HSB A;  2NOH A;  1YQR A;  2NOL A;  2YG8 A;  1PU7 A;  1EBM A;  3FSP A;  1MPG A;  3CWU A;  3OGD A;  4E9G A;  2NOE A;  4EJZ A;  4B22 A;  4B21 A;  2H56 A;  1XG7 A;  4UOB A;  2NOZ A;  3I0X A;  1WEI A;  2OFI A;  2YG9 A;  2JHN A;  1N3C A;  4EA4 A;  1NGN A; 
#chains in the Genus database with same CATH topology
 1LMZ A;  4OFE A;  3S6I A;  4BDY A;  5DPK A;  2NOF A;  3OH6 A;  3S3O A;  3FHF A;  4AIA A;  3FHG A;  1LWW A;  3G0Q A;  1LWY A;  3OYD A;  1KQJ A;  4YPR A;  4IKF A;  4BDZ A;  3S3N A;  3OYJ A;  4EVV A;  3F10 A;  1RRQ A;  1KEA A;  4BE2 A;  1XQP A;  5FRO A;  3L2U A;  3OYH A;  1MUY A;  4ZTF A;  2JHJ A;  4E7K A;  4E7L A;  3CWS A;  1P59 A;  3N0U A;  2W04 A;  4E9E A;  4BE0 A;  3F0Z A;  2JG6 A;  4BE1 A;  4B23 A;  5KN8 A;  4BAC A;  4E9H A;  3L2W A;  1KG7 A;  3OY9 A;  3IHO A;  1LWV A;  3S3M A;  4UNF A;  3CWT A;  1HU0 A;  1N39 A;  1NKU A;  1RRS A;  4EJY A;  1KG3 A;  1PVS A;  5KN9 A;  5AN4 A;  4ZTJ A;  2OFK A;  1YQL A;  3CVS A;  4EW0 A;  1M3Q A;  1U84 A;  4AI4 A;  3OYK A;  1ORN A;  3OYG A;  2I5W A;  3D4V A;  1FN7 A;  1WEF A;  4E7J A;  1KG2 A;  1N3A A;  4PII A;  3OYE A;  1PU6 A;  3KNT A;  5FRN A;  3CW7 A;  2ABK A;  1YQK A;  3OH9 A;  1DIZ A;  3OYM A;  2NOB A;  3OS0 A;  4YPH A;  3OYI A;  4E7H A;  4YOQ A;  1KG4 A;  3NNQ A;  1KO9 A;  3N5N X;  3VW4 A;  3KTU A;  1PU8 A;  1VRL A;  4OFA A;  4NZG A;  3LCN A;  3R2X C;  3OYL A;  5CHZ A;  4EW4 A;  1YQM A;  1M3H A;  3OS1 A;  3L2R A;  3CWA A;  1P7M A;  4E9F A;  2NOI A;  2XHI A;  3CVT A;  4EA5 A;  3L2Q A;  3I0W A;  3IH7 A;  2JPS A;  4AI5 A;  1MUD A;  3OS2 A;  1WEG A;  1XQO A;  4OFH A;  4DK9 A;  3OYB A;  4E7I A;  1MUN A;  1ORP A;  1KG6 A;  1KG5 A;  4B24 A;  4HSB A;  2NOH A;  1YQR A;  2NOL A;  2YG8 A;  1PU7 A;  1EBM A;  2V75 A;  5FRM A;  3OYF A;  3FSP A;  1MPG A;  3CWU A;  3OGD A;  4E9G A;  2NOE A;  4EJZ A;  4B22 A;  4B21 A;  2H56 A;  3OYA A;  1XG7 A;  4UOB A;  2NOZ A;  3I0X A;  1WEI A;  2OFI A;  3OYC A;  2YG9 A;  3L2V A;  2JHN A;  2W03 A;  1N3C A;  3OYN A;  4EA4 A;  1NGN A; 
#chains in the Genus database with same CATH homology
 1LMZ A;  4OFE A;  3S6I A;  5DPK A;  2NOF A;  3OH6 A;  3FHF A;  4AIA A;  3FHG A;  1LWW A;  3G0Q A;  1LWY A;  1KQJ A;  4YPR A;  4EVV A;  3F10 A;  1RRQ A;  1KEA A;  1XQP A;  1MUY A;  2JHJ A;  3CWS A;  1P59 A;  3N0U A;  4E9E A;  3F0Z A;  2JG6 A;  4B23 A;  5KN8 A;  4E9H A;  1KG7 A;  3IHO A;  1LWV A;  4UNF A;  3CWT A;  1HU0 A;  1N39 A;  1NKU A;  1RRS A;  4EJY A;  1KG3 A;  1PVS A;  5KN9 A;  5AN4 A;  2OFK A;  1YQL A;  3CVS A;  4EW0 A;  1M3Q A;  4AI4 A;  1ORN A;  2I5W A;  3D4V A;  1FN7 A;  1WEF A;  1KG2 A;  1N3A A;  4PII A;  1PU6 A;  3KNT A;  3CW7 A;  2ABK A;  1YQK A;  3OH9 A;  1DIZ A;  2NOB A;  4YPH A;  4YOQ A;  1KG4 A;  1KO9 A;  3N5N X;  3KTU A;  1PU8 A;  1VRL A;  4OFA A;  5CHZ A;  4EW4 A;  1YQM A;  1M3H A;  3CWA A;  1P7M A;  4E9F A;  2NOI A;  2XHI A;  3CVT A;  4EA5 A;  3I0W A;  3IH7 A;  4AI5 A;  1MUD A;  1WEG A;  1XQO A;  4OFH A;  4DK9 A;  1MUN A;  1ORP A;  1KG6 A;  1KG5 A;  4B24 A;  4HSB A;  2NOH A;  1YQR A;  2NOL A;  2YG8 A;  1PU7 A;  1EBM A;  3FSP A;  1MPG A;  3CWU A;  3OGD A;  4E9G A;  2NOE A;  4EJZ A;  4B22 A;  4B21 A;  2H56 A;  1XG7 A;  4UOB A;  2NOZ A;  3I0X A;  1WEI A;  2OFI A;  2YG9 A;  2JHN A;  1N3C A;  4EA4 A;  1NGN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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