2ABKA

Refinement of the native structure of endonuclease iii to a resolution of 1.85 angstrom
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
211
structure length
211
Chain Sequence
MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Endonuclease
publication title Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
pubmed rcsb
molecule keywords ENDONUCLEASE III
total genus 72
structure length 211
sequence length 211
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 1995-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2abkA01
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2abkA02
4EJYA 2JG6A 2YG9A 1YQLA 3N0UA 1MUNA 1KEAA 4EW4A 1VRLA 1LWWA 1XG7A 4E9FA 4B21A 1KG5A 1RRQA 4AI5A 4B24A 1YQMA 1HU0A 1YQRA 4DK9A 2H56A 2NOHA 1EBMA 2NOIA 4AI4A 1N3CA 1KG6A 4EA4A 1XQOA 3OH6A 2NOEA 1MUDA 1PU6A 1NGNA 3CWTA 1KO9A 1M3QA 4E9EA 3CWAA 1KG3A 4YPHA 1LMZA 3OGDA 1M3HA 4EJZA 3D4VA 2XHIA 2OFKA 4PIIA 2YG8A 4OFEA 1KG2A 4E9GA 3FHFA 1RRSA 3KTUA 1PU7A 2JHJA 2NOFA 4B22A 4OFAA 4OFHA 1PVSA 2NOBA 4AIAA 4EA5A 3IH7A 3FHGA 1XQPA 1KQJA 3I0XA 2I5WA 5KN8A 4UOBA 1FN7A 4B23A 3I0WA 2NOLA 3G0QA 3KNTA 4EW0A 5AN4A 3CVSA 2ABKA 1MPGA 3N5NX 4YOQA 1NKUA 1LWYA 3FSPA 1ORPA 1LWVA 4E9HA 3CWUA 1KG7A 1WEFA 1ORNA 4EVVA 1KG4A 2JHNA 1PU8A 3CW7A 1P59A 1WEIA 5DPKA 5KN9A 3F10A 3S6IA 1P7MA 3F0ZA 3OH9A 3CVTA 1WEGA 2NOZA 1N3AA 1N39A 4HSBA 3IHOA 5CHZA 1MUYA 3CWSA 1YQKA 4YPRA 1DIZA 2OFIA 4UNFA
chains in the Genus database with same CATH superfamily
4EJYA 2JG6A 2YG9A 1YQLA 3N0UA 4E7KA 1MUNA 1KEAA 4EW4A 2W03A 1VRLA 1XG7A 1LWWA 4E9FA 3OYEA 3R2XC 3OYMA 4B21A 1KG5A 5FROA 1RRQA 4AI5A 4B24A 5FRNA 1YQMA 1HU0A 1YQRA 4DK9A 2H56A 3L2QA 2NOHA 3L2RA 1EBMA 3OS2A 3OS0A 2NOIA 4BDYA 4AI4A 4IKFA 1N3CA 1U84A 1KG6A 4EA4A 1XQOA 3OH6A 2NOEA 1MUDA 1PU6A 4NZGA 1NGNA 3CWTA 3L2UA 3OS1A 3OYBA 1KO9A 1M3QA 4E9EA 3CWAA 1KG3A 3NNQA 4YPHA 1LMZA 3OGDA 1M3HA 4EJZA 3L2VA 3D4VA 2XHIA 2OFKA 4PIIA 2YG8A 4OFEA 4E7HA 1KG2A 4E9GA 3FHFA 1RRSA 3KTUA 4ZTFA 3OY9A 1PU7A 2JHJA 4E7IA 2NOFA 4B22A 4OFAA 4OFHA 1PVSA 2NOBA 4AIAA 4EA5A 4ZTJA 3IH7A 3FHGA 1XQPA 3OYDA 1KQJA 3OYCA 3I0XA 4BE1A 2I5WA 5KN8A 5FRMA 4UOBA 1FN7A 4B23A 3I0WA 3S3NA 2V75A 2NOLA 3G0QA 3KNTA 4EW0A 5AN4A 3CVSA 2ABKA 1MPGA 3N5NX 4YOQA 3OYAA 1NKUA 1LWYA 3FSPA 3OYHA 1ORPA 1LWVA 4E9HA 3S3OA 3OYFA 3OYJA 3CWUA 3S3MA 1KG7A 1WEFA 1ORNA 3OYIA 4EVVA 4E7LA 3OYKA 1KG4A 3VW4A 4BE0A 4BACA 2JHNA 1PU8A 3OYNA 4BDZA 3CW7A 4BE2A 3OYGA 1P59A 1WEIA 5DPKA 5KN9A 4E7JA 2JPSA 3LCNA 3F10A 3S6IA 1P7MA 3F0ZA 3OH9A 3CVTA 1WEGA 2NOZA 1N3AA 1N39A 3OYLA 3L2WA 4HSBA 3IHOA 5CHZA 2W04A 1MUYA 3CWSA 1YQKA 4YPRA 1DIZA 2OFIA 4UNFA
chains in the Genus database with same CATH topology
4EJYA 2JG6A 2YG9A 1YQLA 3N0UA 1MUNA 1KEAA 4EW4A 1VRLA 1LWWA 1XG7A 4E9FA 4B21A 1KG5A 1RRQA 4AI5A 4B24A 1YQMA 1HU0A 1YQRA 4DK9A 2H56A 2NOHA 1EBMA 2NOIA 4AI4A 1N3CA 1KG6A 4EA4A 1XQOA 3OH6A 2NOEA 1MUDA 1PU6A 1NGNA 3CWTA 1KO9A 1M3QA 4E9EA 3CWAA 1KG3A 4YPHA 1LMZA 3OGDA 1M3HA 4EJZA 3D4VA 2XHIA 2OFKA 4PIIA 2YG8A 4OFEA 1KG2A 4E9GA 3FHFA 1RRSA 3KTUA 1PU7A 2JHJA 2NOFA 4B22A 4OFAA 4OFHA 1PVSA 2NOBA 4AIAA 4EA5A 3IH7A 3FHGA 1XQPA 1KQJA 3I0XA 2I5WA 5KN8A 4UOBA 1FN7A 4B23A 3I0WA 2NOLA 3G0QA 3KNTA 4EW0A 5AN4A 3CVSA 2ABKA 1MPGA 3N5NX 4YOQA 1NKUA 1LWYA 3FSPA 1ORPA 1LWVA 4E9HA 3CWUA 1KG7A 1WEFA 1ORNA 4EVVA 1KG4A 2JHNA 1PU8A 3CW7A 1P59A 1WEIA 5DPKA 5KN9A 3F10A 3S6IA 1P7MA 3F0ZA 3OH9A 3CVTA 1WEGA 2NOZA 1N3AA 1N39A 4HSBA 3IHOA 5CHZA 1MUYA 3CWSA 1YQKA 4YPRA 1DIZA 2OFIA 4UNFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EJY A;  2JG6 A;  2YG9 A;  1YQL A;  3N0U A;  1MUN A;  1KEA A;  4EW4 A;  1VRL A;  1LWW A;  1XG7 A;  4E9F A;  4B21 A;  1KG5 A;  1RRQ A;  4AI5 A;  4B24 A;  1YQM A;  1HU0 A;  1YQR A;  4DK9 A;  2H56 A;  2NOH A;  1EBM A;  2NOI A;  4AI4 A;  1N3C A;  1KG6 A;  4EA4 A;  1XQO A;  3OH6 A;  2NOE A;  1MUD A;  1PU6 A;  1NGN A;  3CWT A;  1KO9 A;  1M3Q A;  4E9E A;  3CWA A;  1KG3 A;  4YPH A;  1LMZ A;  3OGD A;  1M3H A;  4EJZ A;  3D4V A;  2XHI A;  2OFK A;  4PII A;  2YG8 A;  4OFE A;  1KG2 A;  4E9G A;  3FHF A;  1RRS A;  3KTU A;  1PU7 A;  2JHJ A;  2NOF A;  4B22 A;  4OFA A;  4OFH A;  1PVS A;  2NOB A;  4AIA A;  4EA5 A;  3IH7 A;  3FHG A;  1XQP A;  1KQJ A;  3I0X A;  2I5W A;  5KN8 A;  4UOB A;  1FN7 A;  4B23 A;  3I0W A;  2NOL A;  3G0Q A;  3KNT A;  4EW0 A;  5AN4 A;  3CVS A;  2ABK A;  1MPG A;  3N5N X;  4YOQ A;  1NKU A;  1LWY A;  3FSP A;  1ORP A;  1LWV A;  4E9H A;  3CWU A;  1KG7 A;  1WEF A;  1ORN A;  4EVV A;  1KG4 A;  2JHN A;  1PU8 A;  3CW7 A;  1P59 A;  1WEI A;  5DPK A;  5KN9 A;  3F10 A;  3S6I A;  1P7M A;  3F0Z A;  3OH9 A;  3CVT A;  1WEG A;  2NOZ A;  1N3A A;  1N39 A;  4HSB A;  3IHO A;  5CHZ A;  1MUY A;  3CWS A;  1YQK A;  4YPR A;  1DIZ A;  2OFI A;  4UNF A; 
#chains in the Genus database with same CATH topology
 4EJY A;  2JG6 A;  2YG9 A;  1YQL A;  3N0U A;  4E7K A;  1MUN A;  1KEA A;  4EW4 A;  2W03 A;  1VRL A;  1XG7 A;  1LWW A;  4E9F A;  3OYE A;  3R2X C;  3OYM A;  4B21 A;  1KG5 A;  5FRO A;  1RRQ A;  4AI5 A;  4B24 A;  5FRN A;  1YQM A;  1HU0 A;  1YQR A;  4DK9 A;  2H56 A;  3L2Q A;  2NOH A;  3L2R A;  1EBM A;  3OS2 A;  3OS0 A;  2NOI A;  4BDY A;  4AI4 A;  4IKF A;  1N3C A;  1U84 A;  1KG6 A;  4EA4 A;  1XQO A;  3OH6 A;  2NOE A;  1MUD A;  1PU6 A;  4NZG A;  1NGN A;  3CWT A;  3L2U A;  3OS1 A;  3OYB A;  1KO9 A;  1M3Q A;  4E9E A;  3CWA A;  1KG3 A;  3NNQ A;  4YPH A;  1LMZ A;  3OGD A;  1M3H A;  4EJZ A;  3L2V A;  3D4V A;  2XHI A;  2OFK A;  4PII A;  2YG8 A;  4OFE A;  4E7H A;  1KG2 A;  4E9G A;  3FHF A;  1RRS A;  3KTU A;  4ZTF A;  3OY9 A;  1PU7 A;  2JHJ A;  4E7I A;  2NOF A;  4B22 A;  4OFA A;  4OFH A;  1PVS A;  2NOB A;  4AIA A;  4EA5 A;  4ZTJ A;  3IH7 A;  3FHG A;  1XQP A;  3OYD A;  1KQJ A;  3OYC A;  3I0X A;  4BE1 A;  2I5W A;  5KN8 A;  5FRM A;  4UOB A;  1FN7 A;  4B23 A;  3I0W A;  3S3N A;  2V75 A;  2NOL A;  3G0Q A;  3KNT A;  4EW0 A;  5AN4 A;  3CVS A;  2ABK A;  1MPG A;  3N5N X;  4YOQ A;  3OYA A;  1NKU A;  1LWY A;  3FSP A;  3OYH A;  1ORP A;  1LWV A;  4E9H A;  3S3O A;  3OYF A;  3OYJ A;  3CWU A;  3S3M A;  1KG7 A;  1WEF A;  1ORN A;  3OYI A;  4EVV A;  4E7L A;  3OYK A;  1KG4 A;  3VW4 A;  4BE0 A;  4BAC A;  2JHN A;  1PU8 A;  3OYN A;  4BDZ A;  3CW7 A;  4BE2 A;  3OYG A;  1P59 A;  1WEI A;  5DPK A;  5KN9 A;  4E7J A;  2JPS A;  3LCN A;  3F10 A;  3S6I A;  1P7M A;  3F0Z A;  3OH9 A;  3CVT A;  1WEG A;  2NOZ A;  1N3A A;  1N39 A;  3OYL A;  3L2W A;  4HSB A;  3IHO A;  5CHZ A;  2W04 A;  1MUY A;  3CWS A;  1YQK A;  4YPR A;  1DIZ A;  2OFI A;  4UNF A; 
#chains in the Genus database with same CATH homology
 4EJY A;  2JG6 A;  2YG9 A;  1YQL A;  3N0U A;  1MUN A;  1KEA A;  4EW4 A;  1VRL A;  1LWW A;  1XG7 A;  4E9F A;  4B21 A;  1KG5 A;  1RRQ A;  4AI5 A;  4B24 A;  1YQM A;  1HU0 A;  1YQR A;  4DK9 A;  2H56 A;  2NOH A;  1EBM A;  2NOI A;  4AI4 A;  1N3C A;  1KG6 A;  4EA4 A;  1XQO A;  3OH6 A;  2NOE A;  1MUD A;  1PU6 A;  1NGN A;  3CWT A;  1KO9 A;  1M3Q A;  4E9E A;  3CWA A;  1KG3 A;  4YPH A;  1LMZ A;  3OGD A;  1M3H A;  4EJZ A;  3D4V A;  2XHI A;  2OFK A;  4PII A;  2YG8 A;  4OFE A;  1KG2 A;  4E9G A;  3FHF A;  1RRS A;  3KTU A;  1PU7 A;  2JHJ A;  2NOF A;  4B22 A;  4OFA A;  4OFH A;  1PVS A;  2NOB A;  4AIA A;  4EA5 A;  3IH7 A;  3FHG A;  1XQP A;  1KQJ A;  3I0X A;  2I5W A;  5KN8 A;  4UOB A;  1FN7 A;  4B23 A;  3I0W A;  2NOL A;  3G0Q A;  3KNT A;  4EW0 A;  5AN4 A;  3CVS A;  2ABK A;  1MPG A;  3N5N X;  4YOQ A;  1NKU A;  1LWY A;  3FSP A;  1ORP A;  1LWV A;  4E9H A;  3CWU A;  1KG7 A;  1WEF A;  1ORN A;  4EVV A;  1KG4 A;  2JHN A;  1PU8 A;  3CW7 A;  1P59 A;  1WEI A;  5DPK A;  5KN9 A;  3F10 A;  3S6I A;  1P7M A;  3F0Z A;  3OH9 A;  3CVT A;  1WEG A;  2NOZ A;  1N3A A;  1N39 A;  4HSB A;  3IHO A;  5CHZ A;  1MUY A;  3CWS A;  1YQK A;  4YPR A;  1DIZ A;  2OFI A;  4UNF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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