2AGHB

Structural basis for cooperative transcription factor binding to the cbp coactivator
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
87
structure length
87
Chain Sequence
GVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Myb proto-oncogene protein
total genus 29
structure length 87
sequence length 87
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02172 KIX KIX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.20 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Coactivator CBP, KIX domain 2aghB00
2K0NA 1SB0A 2AGHB 2KWFA 2LQHA 2LXTA 4I9OA 1KDXA 2GUTA 2LQIA 4D7XA 2LXSA
chains in the Genus database with same CATH superfamily
3M99C 4OTUA 1NT2B 4OR0A 1HK2A 2E0YA 5IIXA 1TXUA 2EFCA 2XVVA 5FUOA 2BXEA 3UIVA 2BXBA 4HGMB 2LOQA 1H9ZA 1E7BA 1LOTA 4NAWB 1E7EA 2I2ZA 2LQIA 5ID9A 3G9KD 2XSIA 1IJGA 2BXMA 3NMUA 3V09A 3JRYA 4M70B 5IFOA 2XVQA 2V36A 2XW0A 2BXAA 3V08A 1MM8A 5IIHA 4S1YA 4F5SA 3TDLA 2DBXA 3FWCC 1HK3A 4GDXA 2JUHA 3LU8A 5IIUA 2QHBA 3KIKA 1E7FA 4TQ0A 2DYMA 1MIYA 4N0UD 2BXDA 1JNBA 3A75A 2CKXA 1BKEA 2BXCA 3B9LA 4IW1A 1HK5A 1J78A 3LU6A 1E78A 1MA9A 2XMOA 4K71A 3SIUB 4ZUXV 1MUHA 4JK4A 1MIWA 2VUEA 4ZCGA 4Z69A 3MHHB 1MUSA 2BX8A 2Z8IA 5IJEA 5D7GA 3MHSB 2BXIA 4FK5B 4ZBRA 1SB0A 2DG5A 4C31B 2BXOA 3BPJA 4FJCB 4ZC6A 4FIPB 2BXKA 3VQIA 2ROHA 2OZBB 4F5UA 3FWBC 2XVUA 4WA6B 2LXSA 1E7CA 5DBYA 4L8UA 2DYOA 4PO0A 5B5TA 3GA9L 1KW2A 4W4UB 2BXGA 4ZBQA 1MIVA 4N0FD 2BXFA 1GNJA 3V03A 4BKEA 2I30A 2EFDA 3WHSA 3FNMA 3JQZA 3NVMA 4TQ1A 4DM0A 4OTTA 4I9OA 1H5WA 2YDFA 5HOZA 2XW1A 3PLAA 1TF0A 4OT2A 1KXPD 2BXPA 1HK4A 1O9XA 1E7GA 4Z9OA 2KWFA 3ECPA 2BXHA 2LQHA 4N3ZA 1UORA 5GHKA 4EMXA 1E7AA 2DBWA 2E0XA 4D7XA 2K0NA 1J7EA 4LUFA 3NVIA 2VDBA 5GINA 4G03A 2QM6A 2XVWA 3NVKA 4LB9A 3CX9A 4DHXB 2DBUA 2Z8KA 3H37A 3W1SA 3B9MA 3WHQA 1VFIA 4LA0A 2NNWA 2KBZA 3LU7A 3SIVB 2AJEA 1AO6A 1GNIA 2OT3A 2EFHA 4LB2A 4E99A 1KDXA 2GUTA 4IW2A 1VZSA 2Z8JA 4J2VA 3SQJA 5GIOA 3KJLA 3H3AA 1HA2A 1LNSA 4L9KA 2VUFA 1HK1A 4MBEC 4GG2A 4K2CA 4BY9C 4GDKB 5BPKA 5IJFA 3ICXA 2LXTA 5ID7A 2BXQA 2EFEA 2QMCA 4GDLB 2NQOA 5GIPA 4F5TA 2BXLA 3A73A 4G01A 4HGKA 1BJ5A 3GQUA 5IJ5A 4F5VA 3GQXA 1N5UA 4G04A 5DQFA 2BXNA 2AGHB 4L9QA 1E7IA 1BM0A 3WHRA 1E7HA 1FOUA 4ZBKA 4LUHA
chains in the Genus database with same CATH topology
2K0NA 1SB0A 2AGHB 2KWFA 2LQHA 2LXTA 4I9OA 1KDXA 2GUTA 2LQIA 4D7XA 2LXSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K0N A;  1SB0 A;  2AGH B;  2KWF A;  2LQH A;  2LXT A;  4I9O A;  1KDX A;  2GUT A;  2LQI A;  4D7X A;  2LXS A; 
#chains in the Genus database with same CATH topology
 3M99 C;  4OTU A;  1NT2 B;  4OR0 A;  1HK2 A;  2E0Y A;  5IIX A;  1TXU A;  2EFC A;  2XVV A;  5FUO A;  2BXE A;  3UIV A;  2BXB A;  4HGM B;  2LOQ A;  1H9Z A;  1E7B A;  1LOT A;  4NAW B;  1E7E A;  2I2Z A;  2LQI A;  5ID9 A;  3G9K D;  2XSI A;  1IJG A;  2BXM A;  3NMU A;  3V09 A;  3JRY A;  4M70 B;  5IFO A;  2XVQ A;  2V36 A;  2XW0 A;  2BXA A;  3V08 A;  1MM8 A;  5IIH A;  4S1Y A;  4F5S A;  3TDL A;  2DBX A;  3FWC C;  1HK3 A;  4GDX A;  2JUH A;  3LU8 A;  5IIU A;  2QHB A;  3KIK A;  1E7F A;  4TQ0 A;  2DYM A;  1MIY A;  4N0U D;  2BXD A;  1JNB A;  3A75 A;  2CKX A;  1BKE A;  2BXC A;  3B9L A;  4IW1 A;  1HK5 A;  1J78 A;  3LU6 A;  1E78 A;  1MA9 A;  2XMO A;  4K71 A;  3SIU B;  4ZUX V;  1MUH A;  4JK4 A;  1MIW A;  2VUE A;  4ZCG A;  4Z69 A;  3MHH B;  1MUS A;  2BX8 A;  2Z8I A;  5IJE A;  5D7G A;  3MHS B;  2BXI A;  4FK5 B;  4ZBR A;  1SB0 A;  2DG5 A;  4C31 B;  2BXO A;  3BPJ A;  4FJC B;  4ZC6 A;  4FIP B;  2BXK A;  3VQI A;  2ROH A;  2OZB B;  4F5U A;  3FWB C;  2XVU A;  4WA6 B;  2LXS A;  1E7C A;  5DBY A;  4L8U A;  2DYO A;  4PO0 A;  5B5T A;  3GA9 L;  1KW2 A;  4W4U B;  2BXG A;  4ZBQ A;  1MIV A;  4N0F D;  2BXF A;  1GNJ A;  3V03 A;  4BKE A;  2I30 A;  2EFD A;  3WHS A;  3FNM A;  3JQZ A;  3NVM A;  4TQ1 A;  4DM0 A;  4OTT A;  4I9O A;  1H5W A;  2YDF A;  5HOZ A;  2XW1 A;  3PLA A;  1TF0 A;  4OT2 A;  1KXP D;  2BXP A;  1HK4 A;  1O9X A;  1E7G A;  4Z9O A;  2KWF A;  3ECP A;  2BXH A;  2LQH A;  4N3Z A;  1UOR A;  5GHK A;  4EMX A;  1E7A A;  2DBW A;  2E0X A;  4D7X A;  2K0N A;  1J7E A;  4LUF A;  3NVI A;  2VDB A;  5GIN A;  4G03 A;  2QM6 A;  2XVW A;  3NVK A;  4LB9 A;  3CX9 A;  4DHX B;  2DBU A;  2Z8K A;  3H37 A;  3W1S A;  3B9M A;  3WHQ A;  1VFI A;  4LA0 A;  2NNW A;  2KBZ A;  3LU7 A;  3SIV B;  2AJE A;  1AO6 A;  1GNI A;  2OT3 A;  2EFH A;  4LB2 A;  4E99 A;  1KDX A;  2GUT A;  4IW2 A;  1VZS A;  2Z8J A;  4J2V A;  3SQJ A;  5GIO A;  3KJL A;  3H3A A;  1HA2 A;  1LNS A;  4L9K A;  2VUF A;  1HK1 A;  4MBE C;  4GG2 A;  4K2C A;  4BY9 C;  4GDK B;  5BPK A;  5IJF A;  3ICX A;  2LXT A;  5ID7 A;  2BXQ A;  2EFE A;  2QMC A;  4GDL B;  2NQO A;  5GIP A;  4F5T A;  2BXL A;  3A73 A;  4G01 A;  4HGK A;  1BJ5 A;  3GQU A;  5IJ5 A;  4F5V A;  3GQX A;  1N5U A;  4G04 A;  5DQF A;  2BXN A;  2AGH B;  4L9Q A;  1E7I A;  1BM0 A;  3WHR A;  1E7H A;  1FOU A;  4ZBK A;  4LUH A; 
#chains in the Genus database with same CATH homology
 2K0N A;  1SB0 A;  2AGH B;  2KWF A;  2LQH A;  2LXT A;  4I9O A;  1KDX A;  2GUT A;  2LQI A;  4D7X A;  2LXS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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