2BXAA

Human serum albumin complexed with 3-carboxy-4-methyl-5-propyl-2- furanpropanoic acid (cmpf)
Total Genus 219
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
219
sequence length
578
structure length
569
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 219
structure length 569
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA05
2XVQA 1E7GA 4F5TA 2BXMA 4E99A 2XW0A 4HGKA 4BKEA 3LU7A 1BM0A 2BXIA 2VUFA 2BXOA 1E7AA 4G03A 1E7FA 4HGMB 1HK5A 1H9ZA 2VDBA 5IJ5A 5IIXA 4IW2A 4LB9A 3SQJA 4J2VA 2BXNA 5ID7A 4OR0A 3CX9A 1E7CA 1HK2A 3UIVA 1MA9A 4F5UA 1E7HA 3JQZA 2BXQA 1UORA 5DBYA 4ZBQA 4LUHA 1LOTA 3A73A 1GNIA 1HK3A 4LB2A 4JK4A 1J7EA 2BXAA 1BKEA 4G04A 4PO0A 1E78A 2BXFA 2YDFA 1E7EA 1GNJA 2I30A 4N0UD 5ID9A 2XW1A 1HK4A 4LA0A 1HA2A 4F5SA 2XSIA 3B9LA 5IFOA 4LUFA 1E7IA 1AO6A 4L9KA 2BXLA 2I2ZA 3TDLA 3JRYA 3V03A 1KW2A 4N0FD 4ZBRA 1TF0A 1N5UA 4Z69A 2XVVA 2BXCA 2BXDA 2BXPA 1BJ5A 3LU8A 4IW1A 5FUOA 3B9MA 5IIHA 4K71A 2BX8A 4S1YA 5HOZA 1O9XA 5GHKA 4F5VA 2XVWA 5DQFA 4L8UA 4OT2A 2BXKA 5IJEA 2BXHA 2BXEA 2BXBA 2VUEA 4EMXA 1E7BA 1HK1A 2BXGA 3V09A 4K2CA 1KXPD 5IIUA 3LU6A 1J78A 3V08A 5IJFA 2XVUA 4L9QA
chains in the Genus database with same CATH superfamily
2XVQA 1TXUA 4FJCB 2DYOA 1E7GA 4F5TA 2BXMA 4E99A 2XW0A 4HGKA 4BKEA 3LU7A 1BM0A 2BXIA 2VUFA 2BXOA 1SB0A 1E7AA 3NVIA 3SIUB 4G03A 1VFIA 3KJLA 2DYMA 2Z8JA 1E7FA 4HGMB 3H3AA 3KIKA 4MBEC 1HK5A 4OTUA 5GIPA 1H9ZA 4DM0A 1JNBA 2E0YA 2LXTA 2VDBA 2LQHA 3FWBC 4GDXA 4IW2A 5IJ5A 5IIXA 2DG5A 5BPKA 3NVKA 3WHQA 4LB9A 2AJEA 2E0XA 4GDLB 3SQJA 2LOQA 4J2VA 4TQ0A 3VQIA 2BXNA 2EFCA 5ID7A 2ROHA 1LNSA 1MIWA 4OR0A 3WHRA 3G9KD 3CX9A 1E7CA 1HK2A 3UIVA 1MA9A 4GG2A 1E7HA 2CKXA 3JQZA 2BXQA 4F5UA 1UORA 3WHSA 5GINA 1MUSA 4G01A 5DBYA 4NAWB 4L9QA 4ZBKA 2LQIA 1LOTA 2NNWA 3A73A 3FNMA 4LUHA 1GNIA 4ZBQA 1HK3A 4LB2A 4JK4A 1J7EA 2BXAA 1BKEA 2EFEA 4G04A 4OTTA 4PO0A 1E78A 2BXFA 2QM6A 2YDFA 2Z8IA 1E7EA 5D7GA 1GNJA 4GDKB 2I30A 4D7XA 4N0UD 5ID9A 1MIVA 2XW1A 1HK4A 3FWCC 4LA0A 1MM8A 4BY9C 1HA2A 4F5SA 4ZCGA 2LXSA 2XSIA 3PLAA 3B9LA 2AGHB 5IFOA 4LUFA 1E7IA 3W1SA 1AO6A 2QMCA 4L9KA 3ECPA 2BXLA 2I2ZA 3TDLA 2QHBA 3JRYA 3V03A 2OT3A 1IJGA 1KW2A 4N0FD 2DBXA 4ZBRA 1TF0A 4I9OA 3SIVB 2DBWA 1N5UA 4Z69A 1KDXA 2XVVA 2BXCA 2BXDA 1MIYA 1H5WA 3NVMA 2BXPA 5B5TA 1BJ5A 3LU8A 4IW1A 1NT2B 3B9MA 3H37A 5FUOA 5IIHA 3MHSB 4K71A 2BX8A 2JUHA 4S1YA 1FOUA 5HOZA 3NMUA 1O9XA 4WA6B 2OZBB 5GHKA 4F5VA 2XVWA 4ZC6A 5DQFA 3MHHB 3BPJA 3M99C 4L8UA 4OT2A 2BXKA 3GA9L 2BXHA 5IJEA 4M70B 2BXEA 2BXBA 2VUEA 3GQXA 5GIOA 2DBUA 1E7BA 4Z9OA 4EMXA 4C31B 4TQ1A 3ICXA 2NQOA 1VZSA 3GQUA 2EFDA 2Z8KA 2V36A 1HK1A 4DHXB 2BXGA 2EFHA 3V09A 4FK5B 1MUHA 4K2CA 4N3ZA 2KWFA 1KXPD 5IIUA 3LU6A 1J78A 4FIPB 2KBZA 4W4UB 3V08A 2K0NA 4ZUXV 5IJFA 2XVUA 2GUTA 3A75A 2XMOA
chains in the Genus database with same CATH topology
2XVQA 1TXUA 4FJCB 2DYOA 1E7GA 4F5TA 2BXMA 4E99A 2XW0A 4HGKA 4BKEA 3LU7A 1BM0A 2BXIA 2VUFA 2BXOA 3SIUB 1E7AA 3NVIA 4G03A 1VFIA 3KJLA 2DYMA 2Z8JA 1E7FA 4HGMB 3H3AA 3KIKA 4MBEC 1HK5A 4OTUA 5GIPA 1H9ZA 1JNBA 2E0YA 2VDBA 3FWBC 4GDXA 5IJ5A 4IW2A 5IIXA 3NVKA 2DG5A 5BPKA 3WHQA 4LB9A 2AJEA 2E0XA 4GDLB 3SQJA 2LOQA 4J2VA 4TQ0A 3VQIA 2BXNA 2EFCA 5ID7A 2ROHA 1LNSA 1MIWA 4OR0A 3WHRA 3G9KD 3CX9A 1E7CA 1HK2A 3UIVA 1MA9A 4GG2A 1E7HA 2CKXA 3JQZA 2BXQA 4F5UA 1UORA 3WHSA 5GINA 4G01A 5DBYA 4NAWB 4L9QA 4ZBKA 4LUHA 1LOTA 2NNWA 3A73A 3FNMA 4ZBQA 1GNIA 1HK3A 4LB2A 4JK4A 1J7EA 2BXAA 1BKEA 2EFEA 4G04A 4OTTA 4PO0A 1E78A 2BXFA 2QM6A 2YDFA 2Z8IA 1E7EA 5D7GA 1GNJA 4GDKB 2I30A 4N0UD 5ID9A 1MIVA 2XW1A 1HK4A 3FWCC 4LA0A 4BY9C 1HA2A 4F5SA 4ZCGA 2XSIA 3PLAA 3B9LA 5IFOA 4LUFA 1E7IA 3W1SA 1AO6A 2QMCA 4L9KA 2BXLA 2I2ZA 3TDLA 2QHBA 3JRYA 3V03A 2OT3A 1IJGA 1KW2A 4N0FD 2DBXA 4ZBRA 1TF0A 3SIVB 2DBWA 1N5UA 4Z69A 2XVVA 2BXCA 2BXDA 1MIYA 1H5WA 3NVMA 2BXPA 5B5TA 1BJ5A 3LU8A 4IW1A 1NT2B 3B9MA 3H37A 5FUOA 5IIHA 3MHSB 4K71A 2BX8A 2JUHA 4S1YA 1FOUA 5HOZA 3NMUA 1O9XA 4WA6B 2OZBB 5GHKA 4F5VA 2XVWA 4ZC6A 5DQFA 3MHHB 3M99C 4L8UA 4OT2A 2BXKA 3GA9L 2BXHA 5IJEA 4M70B 2BXEA 2BXBA 2VUEA 3GQXA 5GIOA 2DBUA 1E7BA 4Z9OA 4EMXA 4C31B 4TQ1A 3ICXA 2NQOA 1VZSA 3GQUA 2EFDA 2Z8KA 2V36A 1HK1A 4DHXB 2BXGA 2EFHA 3V09A 4FK5B 4K2CA 4N3ZA 1KXPD 5IIUA 3LU6A 1J78A 4FIPB 2KBZA 4W4UB 3V08A 4ZUXV 5IJFA 2XVUA 3A75A 2XMOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XVQ A;  1E7G A;  4F5T A;  2BXM A;  4E99 A;  2XW0 A;  4HGK A;  4BKE A;  3LU7 A;  1BM0 A;  2BXI A;  2VUF A;  2BXO A;  1E7A A;  4G03 A;  1E7F A;  4HGM B;  1HK5 A;  1H9Z A;  2VDB A;  5IJ5 A;  5IIX A;  4IW2 A;  4LB9 A;  3SQJ A;  4J2V A;  2BXN A;  5ID7 A;  4OR0 A;  3CX9 A;  1E7C A;  1HK2 A;  3UIV A;  1MA9 A;  4F5U A;  1E7H A;  3JQZ A;  2BXQ A;  1UOR A;  5DBY A;  4ZBQ A;  4LUH A;  1LOT A;  3A73 A;  1GNI A;  1HK3 A;  4LB2 A;  4JK4 A;  1J7E A;  2BXA A;  1BKE A;  4G04 A;  4PO0 A;  1E78 A;  2BXF A;  2YDF A;  1E7E A;  1GNJ A;  2I30 A;  4N0U D;  5ID9 A;  2XW1 A;  1HK4 A;  4LA0 A;  1HA2 A;  4F5S A;  2XSI A;  3B9L A;  5IFO A;  4LUF A;  1E7I A;  1AO6 A;  4L9K A;  2BXL A;  2I2Z A;  3TDL A;  3JRY A;  3V03 A;  1KW2 A;  4N0F D;  4ZBR A;  1TF0 A;  1N5U A;  4Z69 A;  2XVV A;  2BXC A;  2BXD A;  2BXP A;  1BJ5 A;  3LU8 A;  4IW1 A;  5FUO A;  3B9M A;  5IIH A;  4K71 A;  2BX8 A;  4S1Y A;  5HOZ A;  1O9X A;  5GHK A;  4F5V A;  2XVW A;  5DQF A;  4L8U A;  4OT2 A;  2BXK A;  5IJE A;  2BXH A;  2BXE A;  2BXB A;  2VUE A;  4EMX A;  1E7B A;  1HK1 A;  2BXG A;  3V09 A;  4K2C A;  1KXP D;  5IIU A;  3LU6 A;  1J78 A;  3V08 A;  5IJF A;  2XVU A;  4L9Q A; 
#chains in the Genus database with same CATH topology
 2XVQ A;  1TXU A;  4FJC B;  2DYO A;  1E7G A;  4F5T A;  2BXM A;  4E99 A;  2XW0 A;  4HGK A;  4BKE A;  3LU7 A;  1BM0 A;  2BXI A;  2VUF A;  2BXO A;  1SB0 A;  1E7A A;  3NVI A;  3SIU B;  4G03 A;  1VFI A;  3KJL A;  2DYM A;  2Z8J A;  1E7F A;  4HGM B;  3H3A A;  3KIK A;  4MBE C;  1HK5 A;  4OTU A;  5GIP A;  1H9Z A;  4DM0 A;  1JNB A;  2E0Y A;  2LXT A;  2VDB A;  2LQH A;  3FWB C;  4GDX A;  4IW2 A;  5IJ5 A;  5IIX A;  2DG5 A;  5BPK A;  3NVK A;  3WHQ A;  4LB9 A;  2AJE A;  2E0X A;  4GDL B;  3SQJ A;  2LOQ A;  4J2V A;  4TQ0 A;  3VQI A;  2BXN A;  2EFC A;  5ID7 A;  2ROH A;  1LNS A;  1MIW A;  4OR0 A;  3WHR A;  3G9K D;  3CX9 A;  1E7C A;  1HK2 A;  3UIV A;  1MA9 A;  4GG2 A;  1E7H A;  2CKX A;  3JQZ A;  2BXQ A;  4F5U A;  1UOR A;  3WHS A;  5GIN A;  1MUS A;  4G01 A;  5DBY A;  4NAW B;  4L9Q A;  4ZBK A;  2LQI A;  1LOT A;  2NNW A;  3A73 A;  3FNM A;  4LUH A;  1GNI A;  4ZBQ A;  1HK3 A;  4LB2 A;  4JK4 A;  1J7E A;  2BXA A;  1BKE A;  2EFE A;  4G04 A;  4OTT A;  4PO0 A;  1E78 A;  2BXF A;  2QM6 A;  2YDF A;  2Z8I A;  1E7E A;  5D7G A;  1GNJ A;  4GDK B;  2I30 A;  4D7X A;  4N0U D;  5ID9 A;  1MIV A;  2XW1 A;  1HK4 A;  3FWC C;  4LA0 A;  1MM8 A;  4BY9 C;  1HA2 A;  4F5S A;  4ZCG A;  2LXS A;  2XSI A;  3PLA A;  3B9L A;  2AGH B;  5IFO A;  4LUF A;  1E7I A;  3W1S A;  1AO6 A;  2QMC A;  4L9K A;  3ECP A;  2BXL A;  2I2Z A;  3TDL A;  2QHB A;  3JRY A;  3V03 A;  2OT3 A;  1IJG A;  1KW2 A;  4N0F D;  2DBX A;  4ZBR A;  1TF0 A;  4I9O A;  3SIV B;  2DBW A;  1N5U A;  4Z69 A;  1KDX A;  2XVV A;  2BXC A;  2BXD A;  1MIY A;  1H5W A;  3NVM A;  2BXP A;  5B5T A;  1BJ5 A;  3LU8 A;  4IW1 A;  1NT2 B;  3B9M A;  3H37 A;  5FUO A;  5IIH A;  3MHS B;  4K71 A;  2BX8 A;  2JUH A;  4S1Y A;  1FOU A;  5HOZ A;  3NMU A;  1O9X A;  4WA6 B;  2OZB B;  5GHK A;  4F5V A;  2XVW A;  4ZC6 A;  5DQF A;  3MHH B;  3BPJ A;  3M99 C;  4L8U A;  4OT2 A;  2BXK A;  3GA9 L;  2BXH A;  5IJE A;  4M70 B;  2BXE A;  2BXB A;  2VUE A;  3GQX A;  5GIO A;  2DBU A;  1E7B A;  4Z9O A;  4EMX A;  4C31 B;  4TQ1 A;  3ICX A;  2NQO A;  1VZS A;  3GQU A;  2EFD A;  2Z8K A;  2V36 A;  1HK1 A;  4DHX B;  2BXG A;  2EFH A;  3V09 A;  4FK5 B;  1MUH A;  4K2C A;  4N3Z A;  2KWF A;  1KXP D;  5IIU A;  3LU6 A;  1J78 A;  4FIP B;  2KBZ A;  4W4U B;  3V08 A;  2K0N A;  4ZUX V;  5IJF A;  2XVU A;  2GUT A;  3A75 A;  2XMO A; 
#chains in the Genus database with same CATH homology
 2XVQ A;  1TXU A;  4FJC B;  2DYO A;  1E7G A;  4F5T A;  2BXM A;  4E99 A;  2XW0 A;  4HGK A;  4BKE A;  3LU7 A;  1BM0 A;  2BXI A;  2VUF A;  2BXO A;  3SIU B;  1E7A A;  3NVI A;  4G03 A;  1VFI A;  3KJL A;  2DYM A;  2Z8J A;  1E7F A;  4HGM B;  3H3A A;  3KIK A;  4MBE C;  1HK5 A;  4OTU A;  5GIP A;  1H9Z A;  1JNB A;  2E0Y A;  2VDB A;  3FWB C;  4GDX A;  5IJ5 A;  4IW2 A;  5IIX A;  3NVK A;  2DG5 A;  5BPK A;  3WHQ A;  4LB9 A;  2AJE A;  2E0X A;  4GDL B;  3SQJ A;  2LOQ A;  4J2V A;  4TQ0 A;  3VQI A;  2BXN A;  2EFC A;  5ID7 A;  2ROH A;  1LNS A;  1MIW A;  4OR0 A;  3WHR A;  3G9K D;  3CX9 A;  1E7C A;  1HK2 A;  3UIV A;  1MA9 A;  4GG2 A;  1E7H A;  2CKX A;  3JQZ A;  2BXQ A;  4F5U A;  1UOR A;  3WHS A;  5GIN A;  4G01 A;  5DBY A;  4NAW B;  4L9Q A;  4ZBK A;  4LUH A;  1LOT A;  2NNW A;  3A73 A;  3FNM A;  4ZBQ A;  1GNI A;  1HK3 A;  4LB2 A;  4JK4 A;  1J7E A;  2BXA A;  1BKE A;  2EFE A;  4G04 A;  4OTT A;  4PO0 A;  1E78 A;  2BXF A;  2QM6 A;  2YDF A;  2Z8I A;  1E7E A;  5D7G A;  1GNJ A;  4GDK B;  2I30 A;  4N0U D;  5ID9 A;  1MIV A;  2XW1 A;  1HK4 A;  3FWC C;  4LA0 A;  4BY9 C;  1HA2 A;  4F5S A;  4ZCG A;  2XSI A;  3PLA A;  3B9L A;  5IFO A;  4LUF A;  1E7I A;  3W1S A;  1AO6 A;  2QMC A;  4L9K A;  2BXL A;  2I2Z A;  3TDL A;  2QHB A;  3JRY A;  3V03 A;  2OT3 A;  1IJG A;  1KW2 A;  4N0F D;  2DBX A;  4ZBR A;  1TF0 A;  3SIV B;  2DBW A;  1N5U A;  4Z69 A;  2XVV A;  2BXC A;  2BXD A;  1MIY A;  1H5W A;  3NVM A;  2BXP A;  5B5T A;  1BJ5 A;  3LU8 A;  4IW1 A;  1NT2 B;  3B9M A;  3H37 A;  5FUO A;  5IIH A;  3MHS B;  4K71 A;  2BX8 A;  2JUH A;  4S1Y A;  1FOU A;  5HOZ A;  3NMU A;  1O9X A;  4WA6 B;  2OZB B;  5GHK A;  4F5V A;  2XVW A;  4ZC6 A;  5DQF A;  3MHH B;  3M99 C;  4L8U A;  4OT2 A;  2BXK A;  3GA9 L;  2BXH A;  5IJE A;  4M70 B;  2BXE A;  2BXB A;  2VUE A;  3GQX A;  5GIO A;  2DBU A;  1E7B A;  4Z9O A;  4EMX A;  4C31 B;  4TQ1 A;  3ICX A;  2NQO A;  1VZS A;  3GQU A;  2EFD A;  2Z8K A;  2V36 A;  1HK1 A;  4DHX B;  2BXG A;  2EFH A;  3V09 A;  4FK5 B;  4K2C A;  4N3Z A;  1KXP D;  5IIU A;  3LU6 A;  1J78 A;  4FIP B;  2KBZ A;  4W4U B;  3V08 A;  4ZUX V;  5IJF A;  2XVU A;  3A75 A;  2XMO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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