2BXAA

Human serum albumin complexed with 3-carboxy-4-methyl-5-propyl-2- furanpropanoic acid (cmpf)
Total Genus 219
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
219
sequence length
578
structure length
569
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 219
structure length 569
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA05
4N0UD 5IJFA 5IJEA 5IIUA 2XVVA 4LA0A 2I30A 3LU8A 4S1YA 4ZBQA 3B9LA 4IW1A 1HK2A 1J78A 2BXHA 4G04A 2BXNA 3JQZA 5HOZA 4N0FD 1E7EA 2BXCA 4J2VA 2XVQA 2VUEA 2XW0A 2VDBA 2XW1A 2I2ZA 4BKEA 1HK3A 5ID7A 2BXKA 3CX9A 1H9ZA 4F5TA 4JK4A 4F5UA 3A73A 4LUHA 5FUOA 1AO6A 1BJ5A 2BXLA 4IW2A 5IIXA 2VUFA 2BXIA 4EMXA 4OR0A 3B9MA 3V08A 4L9QA 2BXQA 3SQJA 1E7AA 4ZBRA 1KXPD 2BXPA 1N5UA 2XVWA 2XSIA 5DQFA 3JRYA 3V09A 2BXMA 4PO0A 2BXDA 4G03A 2BXOA 1E7CA 2BXGA 1O9XA 5ID9A 4L9KA 1E7FA 2BXFA 1BKEA 4F5VA 4OT2A 1E7GA 4K71A 1J7EA 4LUFA 3TDLA 1E7BA 5DBYA 1GNJA 1HK4A 2BXEA 4F5SA 4HGMB 1HK1A 1LOTA 1GNIA 5GHKA 1TF0A 1E7HA 4Z69A 2BXBA 1E7IA 2BXAA 1HK5A 1KW2A 1BM0A 4LB9A 1UORA 2YDFA 1MA9A 1E78A 4HGKA 2BX8A 4L8UA 3LU7A 1HA2A 4LB2A 5IJ5A 3UIVA 4E99A 3LU6A 4K2CA 2XVUA 5IFOA 3V03A 5IIHA
chains in the Genus database with same CATH superfamily
4N0UD 2QMCA 5IJFA 5IJEA 1VZSA 5IIUA 2XVVA 2LXTA 2I30A 2K0NA 4LA0A 3LU8A 3MHHB 4C31B 2QHBA 1MUHA 4S1YA 3KJLA 1H5WA 3B9LA 1JNBA 2Z8JA 4IW1A 4ZBQA 1HK2A 4GG2A 1J78A 2BXHA 4G04A 2BXNA 3JQZA 5HOZA 2LQIA 4N0FD 1E7EA 3FWCC 2BXCA 2DBUA 4J2VA 4ZBKA 3FWBC 2OT3A 2XVQA 2AGHB 5BPKA 3NMUA 2VUEA 2EFCA 3BPJA 3GA9L 2XW0A 3G9KD 2VDBA 2XW1A 2OZBB 2I2ZA 4BKEA 4DHXB 1HK3A 5ID7A 2BXKA 1NT2B 1MM8A 3CX9A 2AJEA 1H9ZA 4W4UB 1KDXA 4F5TA 4JK4A 4F5UA 3A73A 4LUHA 3VQIA 3M99C 4OTTA 5FUOA 3PLAA 3NVMA 4NAWB 1AO6A 4DM0A 4FK5B 1BJ5A 2BXLA 2NNWA 3W1SA 4IW2A 5IIXA 2VUFA 2BXIA 4EMXA 4BY9C 4OR0A 2EFHA 3B9MA 3SIVB 3V08A 4N3ZA 4L9QA 3MHSB 2BXQA 3SIUB 3SQJA 1E7AA 4ZBRA 3WHRA 3NVIA 2DYOA 1KXPD 4Z9OA 2BXPA 1N5UA 2XVWA 2XSIA 2Z8IA 3FNMA 4G01A 5DQFA 3NVKA 3JRYA 5B5TA 3V09A 1MUSA 3WHSA 2GUTA 2BXMA 3H3AA 4PO0A 4I9OA 2BXDA 4G03A 4ZC6A 2KWFA 2BXOA 2E0YA 1E7CA 2XMOA 2BXGA 1MIYA 1O9XA 5GIPA 4OTUA 5ID9A 4L9KA 1E7FA 2BXFA 1BKEA 4F5VA 4OT2A 3ECPA 3ICXA 2DBXA 2EFEA 1E7GA 4FIPB 4K71A 1J7EA 4LUFA 3H37A 3TDLA 2DYMA 1E7BA 2E0XA 2Z8KA 5DBYA 1GNJA 1HK4A 2BXEA 4GDKB 4ZUXV 4F5SA 1MIVA 4HGMB 1HK1A 1LOTA 2V36A 3A75A 3WHQA 1FOUA 2KBZA 4TQ1A 1GNIA 5GHKA 1TF0A 4GDLB 1MIWA 1E7HA 4D7XA 4WA6B 4Z69A 2BXBA 5GINA 1E7IA 2BXAA 1HK5A 1KW2A 2ROHA 1BM0A 4FJCB 4TQ0A 2DG5A 1LNSA 3GQUA 4ZCGA 4LB9A 1UORA 2LXSA 2QM6A 2YDFA 2CKXA 2JUHA 2LQHA 3GQXA 1MA9A 1E78A 4M70B 4MBEC 3KIKA 4HGKA 1IJGA 2BX8A 2EFDA 4GDXA 4L8UA 3LU7A 1HA2A 4LB2A 5IJ5A 3UIVA 4E99A 1TXUA 1VFIA 3LU6A 2NQOA 2LOQA 4K2CA 2XVUA 5D7GA 5GIOA 2DBWA 5IFOA 3V03A 1SB0A 5IIHA
chains in the Genus database with same CATH topology
4N0UD 2QMCA 5IJFA 5IJEA 1VZSA 5IIUA 2XVVA 4LA0A 2I30A 4C31B 3LU8A 3MHHB 2QHBA 4S1YA 3KJLA 1H5WA 3B9LA 1JNBA 2Z8JA 4IW1A 4ZBQA 1HK2A 4GG2A 1J78A 2BXHA 4G04A 2BXNA 3JQZA 5HOZA 4N0FD 1E7EA 3FWCC 2BXCA 2DBUA 4J2VA 4ZBKA 3FWBC 2OT3A 2XVQA 5BPKA 3NMUA 2VUEA 2EFCA 3GA9L 2XW0A 3G9KD 2VDBA 2XW1A 2OZBB 2I2ZA 4BKEA 4DHXB 1HK3A 5ID7A 2BXKA 1NT2B 3CX9A 2AJEA 1H9ZA 4W4UB 4F5TA 4JK4A 4F5UA 3A73A 4LUHA 3VQIA 3M99C 4OTTA 5FUOA 3PLAA 3NVMA 4NAWB 1AO6A 4FK5B 1BJ5A 2BXLA 2NNWA 3W1SA 4IW2A 5IIXA 2VUFA 2BXIA 4EMXA 4BY9C 4OR0A 2EFHA 3B9MA 3SIVB 3V08A 4N3ZA 4L9QA 3MHSB 2BXQA 3SIUB 3SQJA 1E7AA 4ZBRA 3WHRA 3NVIA 2DYOA 1KXPD 4Z9OA 2BXPA 1N5UA 2XVWA 2XSIA 2Z8IA 3FNMA 4G01A 5DQFA 3NVKA 3JRYA 5B5TA 3V09A 3WHSA 2BXMA 3H3AA 4PO0A 2BXDA 4G03A 4ZC6A 2BXOA 2E0YA 1E7CA 2XMOA 2BXGA 1MIYA 1O9XA 5GIPA 4OTUA 5ID9A 4L9KA 1E7FA 2BXFA 1BKEA 4F5VA 4OT2A 3ICXA 2DBXA 2EFEA 1E7GA 4FIPB 4K71A 1J7EA 4LUFA 3H37A 3TDLA 2DYMA 1E7BA 2E0XA 2Z8KA 5DBYA 1GNJA 1HK4A 2BXEA 4GDKB 4ZUXV 4F5SA 1MIVA 4HGMB 1HK1A 1LOTA 2V36A 3A75A 3WHQA 1FOUA 2KBZA 4TQ1A 1GNIA 5GHKA 1TF0A 4GDLB 1MIWA 1E7HA 4WA6B 4Z69A 2BXBA 5GINA 1E7IA 2BXAA 1HK5A 1KW2A 2ROHA 1BM0A 4FJCB 4TQ0A 2DG5A 1LNSA 3GQUA 4ZCGA 4LB9A 1UORA 2QM6A 2YDFA 2CKXA 2JUHA 3GQXA 1MA9A 1E78A 4M70B 4MBEC 3KIKA 4HGKA 1IJGA 2BX8A 2EFDA 4GDXA 4L8UA 3LU7A 1HA2A 4LB2A 5IJ5A 3UIVA 4E99A 1TXUA 1VFIA 3LU6A 2NQOA 2LOQA 4K2CA 2XVUA 5D7GA 5GIOA 2DBWA 5IFOA 3V03A 5IIHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N0U D;  5IJF A;  5IJE A;  5IIU A;  2XVV A;  4LA0 A;  2I30 A;  3LU8 A;  4S1Y A;  4ZBQ A;  3B9L A;  4IW1 A;  1HK2 A;  1J78 A;  2BXH A;  4G04 A;  2BXN A;  3JQZ A;  5HOZ A;  4N0F D;  1E7E A;  2BXC A;  4J2V A;  2XVQ A;  2VUE A;  2XW0 A;  2VDB A;  2XW1 A;  2I2Z A;  4BKE A;  1HK3 A;  5ID7 A;  2BXK A;  3CX9 A;  1H9Z A;  4F5T A;  4JK4 A;  4F5U A;  3A73 A;  4LUH A;  5FUO A;  1AO6 A;  1BJ5 A;  2BXL A;  4IW2 A;  5IIX A;  2VUF A;  2BXI A;  4EMX A;  4OR0 A;  3B9M A;  3V08 A;  4L9Q A;  2BXQ A;  3SQJ A;  1E7A A;  4ZBR A;  1KXP D;  2BXP A;  1N5U A;  2XVW A;  2XSI A;  5DQF A;  3JRY A;  3V09 A;  2BXM A;  4PO0 A;  2BXD A;  4G03 A;  2BXO A;  1E7C A;  2BXG A;  1O9X A;  5ID9 A;  4L9K A;  1E7F A;  2BXF A;  1BKE A;  4F5V A;  4OT2 A;  1E7G A;  4K71 A;  1J7E A;  4LUF A;  3TDL A;  1E7B A;  5DBY A;  1GNJ A;  1HK4 A;  2BXE A;  4F5S A;  4HGM B;  1HK1 A;  1LOT A;  1GNI A;  5GHK A;  1TF0 A;  1E7H A;  4Z69 A;  2BXB A;  1E7I A;  2BXA A;  1HK5 A;  1KW2 A;  1BM0 A;  4LB9 A;  1UOR A;  2YDF A;  1MA9 A;  1E78 A;  4HGK A;  2BX8 A;  4L8U A;  3LU7 A;  1HA2 A;  4LB2 A;  5IJ5 A;  3UIV A;  4E99 A;  3LU6 A;  4K2C A;  2XVU A;  5IFO A;  3V03 A;  5IIH A; 
#chains in the Genus database with same CATH topology
 4N0U D;  2QMC A;  5IJF A;  5IJE A;  1VZS A;  5IIU A;  2XVV A;  2LXT A;  2I30 A;  2K0N A;  4LA0 A;  3LU8 A;  3MHH B;  4C31 B;  2QHB A;  1MUH A;  4S1Y A;  3KJL A;  1H5W A;  3B9L A;  1JNB A;  2Z8J A;  4IW1 A;  4ZBQ A;  1HK2 A;  4GG2 A;  1J78 A;  2BXH A;  4G04 A;  2BXN A;  3JQZ A;  5HOZ A;  2LQI A;  4N0F D;  1E7E A;  3FWC C;  2BXC A;  2DBU A;  4J2V A;  4ZBK A;  3FWB C;  2OT3 A;  2XVQ A;  2AGH B;  5BPK A;  3NMU A;  2VUE A;  2EFC A;  3BPJ A;  3GA9 L;  2XW0 A;  3G9K D;  2VDB A;  2XW1 A;  2OZB B;  2I2Z A;  4BKE A;  4DHX B;  1HK3 A;  5ID7 A;  2BXK A;  1NT2 B;  1MM8 A;  3CX9 A;  2AJE A;  1H9Z A;  4W4U B;  1KDX A;  4F5T A;  4JK4 A;  4F5U A;  3A73 A;  4LUH A;  3VQI A;  3M99 C;  4OTT A;  5FUO A;  3PLA A;  3NVM A;  4NAW B;  1AO6 A;  4DM0 A;  4FK5 B;  1BJ5 A;  2BXL A;  2NNW A;  3W1S A;  4IW2 A;  5IIX A;  2VUF A;  2BXI A;  4EMX A;  4BY9 C;  4OR0 A;  2EFH A;  3B9M A;  3SIV B;  3V08 A;  4N3Z A;  4L9Q A;  3MHS B;  2BXQ A;  3SIU B;  3SQJ A;  1E7A A;  4ZBR A;  3WHR A;  3NVI A;  2DYO A;  1KXP D;  4Z9O A;  2BXP A;  1N5U A;  2XVW A;  2XSI A;  2Z8I A;  3FNM A;  4G01 A;  5DQF A;  3NVK A;  3JRY A;  5B5T A;  3V09 A;  1MUS A;  3WHS A;  2GUT A;  2BXM A;  3H3A A;  4PO0 A;  4I9O A;  2BXD A;  4G03 A;  4ZC6 A;  2KWF A;  2BXO A;  2E0Y A;  1E7C A;  2XMO A;  2BXG A;  1MIY A;  1O9X A;  5GIP A;  4OTU A;  5ID9 A;  4L9K A;  1E7F A;  2BXF A;  1BKE A;  4F5V A;  4OT2 A;  3ECP A;  3ICX A;  2DBX A;  2EFE A;  1E7G A;  4FIP B;  4K71 A;  1J7E A;  4LUF A;  3H37 A;  3TDL A;  2DYM A;  1E7B A;  2E0X A;  2Z8K A;  5DBY A;  1GNJ A;  1HK4 A;  2BXE A;  4GDK B;  4ZUX V;  4F5S A;  1MIV A;  4HGM B;  1HK1 A;  1LOT A;  2V36 A;  3A75 A;  3WHQ A;  1FOU A;  2KBZ A;  4TQ1 A;  1GNI A;  5GHK A;  1TF0 A;  4GDL B;  1MIW A;  1E7H A;  4D7X A;  4WA6 B;  4Z69 A;  2BXB A;  5GIN A;  1E7I A;  2BXA A;  1HK5 A;  1KW2 A;  2ROH A;  1BM0 A;  4FJC B;  4TQ0 A;  2DG5 A;  1LNS A;  3GQU A;  4ZCG A;  4LB9 A;  1UOR A;  2LXS A;  2QM6 A;  2YDF A;  2CKX A;  2JUH A;  2LQH A;  3GQX A;  1MA9 A;  1E78 A;  4M70 B;  4MBE C;  3KIK A;  4HGK A;  1IJG A;  2BX8 A;  2EFD A;  4GDX A;  4L8U A;  3LU7 A;  1HA2 A;  4LB2 A;  5IJ5 A;  3UIV A;  4E99 A;  1TXU A;  1VFI A;  3LU6 A;  2NQO A;  2LOQ A;  4K2C A;  2XVU A;  5D7G A;  5GIO A;  2DBW A;  5IFO A;  3V03 A;  1SB0 A;  5IIH A; 
#chains in the Genus database with same CATH homology
 4N0U D;  2QMC A;  5IJF A;  5IJE A;  1VZS A;  5IIU A;  2XVV A;  4LA0 A;  2I30 A;  4C31 B;  3LU8 A;  3MHH B;  2QHB A;  4S1Y A;  3KJL A;  1H5W A;  3B9L A;  1JNB A;  2Z8J A;  4IW1 A;  4ZBQ A;  1HK2 A;  4GG2 A;  1J78 A;  2BXH A;  4G04 A;  2BXN A;  3JQZ A;  5HOZ A;  4N0F D;  1E7E A;  3FWC C;  2BXC A;  2DBU A;  4J2V A;  4ZBK A;  3FWB C;  2OT3 A;  2XVQ A;  5BPK A;  3NMU A;  2VUE A;  2EFC A;  3GA9 L;  2XW0 A;  3G9K D;  2VDB A;  2XW1 A;  2OZB B;  2I2Z A;  4BKE A;  4DHX B;  1HK3 A;  5ID7 A;  2BXK A;  1NT2 B;  3CX9 A;  2AJE A;  1H9Z A;  4W4U B;  4F5T A;  4JK4 A;  4F5U A;  3A73 A;  4LUH A;  3VQI A;  3M99 C;  4OTT A;  5FUO A;  3PLA A;  3NVM A;  4NAW B;  1AO6 A;  4FK5 B;  1BJ5 A;  2BXL A;  2NNW A;  3W1S A;  4IW2 A;  5IIX A;  2VUF A;  2BXI A;  4EMX A;  4BY9 C;  4OR0 A;  2EFH A;  3B9M A;  3SIV B;  3V08 A;  4N3Z A;  4L9Q A;  3MHS B;  2BXQ A;  3SIU B;  3SQJ A;  1E7A A;  4ZBR A;  3WHR A;  3NVI A;  2DYO A;  1KXP D;  4Z9O A;  2BXP A;  1N5U A;  2XVW A;  2XSI A;  2Z8I A;  3FNM A;  4G01 A;  5DQF A;  3NVK A;  3JRY A;  5B5T A;  3V09 A;  3WHS A;  2BXM A;  3H3A A;  4PO0 A;  2BXD A;  4G03 A;  4ZC6 A;  2BXO A;  2E0Y A;  1E7C A;  2XMO A;  2BXG A;  1MIY A;  1O9X A;  5GIP A;  4OTU A;  5ID9 A;  4L9K A;  1E7F A;  2BXF A;  1BKE A;  4F5V A;  4OT2 A;  3ICX A;  2DBX A;  2EFE A;  1E7G A;  4FIP B;  4K71 A;  1J7E A;  4LUF A;  3H37 A;  3TDL A;  2DYM A;  1E7B A;  2E0X A;  2Z8K A;  5DBY A;  1GNJ A;  1HK4 A;  2BXE A;  4GDK B;  4ZUX V;  4F5S A;  1MIV A;  4HGM B;  1HK1 A;  1LOT A;  2V36 A;  3A75 A;  3WHQ A;  1FOU A;  2KBZ A;  4TQ1 A;  1GNI A;  5GHK A;  1TF0 A;  4GDL B;  1MIW A;  1E7H A;  4WA6 B;  4Z69 A;  2BXB A;  5GIN A;  1E7I A;  2BXA A;  1HK5 A;  1KW2 A;  2ROH A;  1BM0 A;  4FJC B;  4TQ0 A;  2DG5 A;  1LNS A;  3GQU A;  4ZCG A;  4LB9 A;  1UOR A;  2QM6 A;  2YDF A;  2CKX A;  2JUH A;  3GQX A;  1MA9 A;  1E78 A;  4M70 B;  4MBE C;  3KIK A;  4HGK A;  1IJG A;  2BX8 A;  2EFD A;  4GDX A;  4L8U A;  3LU7 A;  1HA2 A;  4LB2 A;  5IJ5 A;  3UIV A;  4E99 A;  1TXU A;  1VFI A;  3LU6 A;  2NQO A;  2LOQ A;  4K2C A;  2XVU A;  5D7G A;  5GIO A;  2DBW A;  5IFO A;  3V03 A;  5IIH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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