2BXC | Genus

Total Genus 205

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	205
sequence length	578
structure length	578
Chain Sequence	SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transport protein
source organism	Homo sapiens
publication title	Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	205
structure length	578
sequence length	578
chains with identical sequence	B
ec nomenclature
pdb deposition date	2005-07-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxcA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxcA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxcA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxcA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxcA06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxcA05

5IJ5A 1HK5A 1UORA 2BXBA 2XVVA 2BXAA 2BXDA 5IJEA 4G03A 1HA2A 5ID9A 1KXPD 1J78A 1AO6A 3B9LA 4L9QA 4N0FD 3V09A 4F5SA 4J2VA 2YDFA 5DQFA 2XW1A 4S1YA 1H9ZA 2XVQA 2BXEA 1E7BA 4ZBRA 1MA9A 4IW2A 2BXOA 5IIUA 1BM0A 2BXCA 4LUFA 5IFOA 4IW1A 4EMXA 2BXFA 2I2ZA 1BJ5A 1HK2A 5FUOA 1LOTA 4G04A 5GHKA 3LU6A 3CX9A 4E99A 2VDBA 4BKEA 4K2CA 1E7GA 1E78A 2XVUA 2BXKA 1E7AA 4HGKA 4L8UA 3V03A 3V08A 2BXPA 2BX8A 4Z69A 3SQJA 4K71A 4LB9A 1GNJA 1E7EA 2XW0A 4F5VA 5IJFA 1E7CA 4L9KA 4LUHA 4F5TA 1O9XA 4OR0A 2BXLA 4PO0A 2BXNA 2BXQA 2XSIA 4HGMB 1E7FA 2BXMA 3JRYA 1TF0A 4ZBQA 3JQZA 2I30A 2VUFA 1HK3A 1KW2A 1E7HA 4OT2A 2VUEA 1N5UA 2BXIA 1HK1A 3A73A 4N0UD 1J7EA 4LB2A 5HOZA 1GNIA 5IIXA 1HK4A 5IIHA 5ID7A 3TDLA 2BXHA 4LA0A 1E7IA 5DBYA 2XVWA 4JK4A 3UIVA 3LU7A 3LU8A 2BXGA 1BKEA 4F5UA 3B9MA
chains in the Genus database with same CATH superfamily

5IJ5A 1HK5A 1MUHA 1UORA 2BXBA 2XVVA 2LOQA 2DYMA 1H5WA 2BXAA 2BXDA 4D7XA 1KDXA 2QHBA 4FJCB 5GIPA 5IJEA 3MHSB 3H3AA 1MIVA 1HA2A 4G03A 4W4UB 5ID9A 1KXPD 4ZCGA 1J78A 1AO6A 3NVKA 3B9LA 4L9QA 4N0FD 3V09A 1LNSA 4N3ZA 4F5SA 2OZBB 4J2VA 2QMCA 2YDFA 5DQFA 1IJGA 2XW1A 3BPJA 4S1YA 1H9ZA 3VQIA 3NVIA 4GDLB 2XVQA 4GDXA 2BXEA 1E7BA 5B5TA 4ZBRA 1MA9A 3GQUA 4IW2A 5GIOA 2BXOA 5IIUA 1BM0A 2GUTA 2BXCA 4LUFA 5IFOA 5BPKA 2JUHA 3FNMA 4IW1A 3ECPA 4DM0A 4EMXA 2BXFA 2I2ZA 2DG5A 1BJ5A 1HK2A 2AJEA 4DHXB 5FUOA 1LOTA 4G04A 2OT3A 2DBUA 5GHKA 3ICXA 3LU6A 3CX9A 2DBXA 4E99A 2VDBA 4NAWB 2EFCA 3KIKA 4TQ1A 4BKEA 4TQ0A 3SIVB 2AGHB 2Z8IA 4I9OA 4K2CA 1JNBA 1E7GA 4C31B 1FOUA 1E78A 2XVUA 2BXKA 1E7AA 4HGKA 4L8UA 3M99C 3V03A 3WHRA 3WHSA 3V08A 2BXPA 2BX8A 3NMUA 4M70B 2DYOA 4Z69A 2LQIA 4WA6B 3SQJA 4K71A 4LB9A 1GNJA 1E7EA 2EFEA 2V36A 2XW0A 3A75A 3NVMA 2CKXA 2K0NA 3W1SA 4F5VA 5IJFA 2EFDA 1VFIA 2EFHA 5D7GA 4OR0A 1E7CA 4L9KA 4LUHA 4G01A 3MHHB 4F5TA 1O9XA 4GDKB 2KWFA 2BXLA 4GG2A 2BXNA 2BXQA 2XSIA 2LQHA 4HGMB 4MBEC 4OTTA 1E7FA 2BXMA 3FWCC 2NNWA 3JRYA 2E0YA 4OTUA 2Z8JA 4Z9OA 3PLAA 4ZC6A 1TF0A 1VZSA 4ZBQA 3JQZA 1MUSA 1SB0A 2I30A 1MIYA 2VUFA 2LXSA 1NT2B 1HK3A 1KW2A 1E7HA 4OT2A 2VUEA 3SIUB 1N5UA 2BXIA 1HK1A 3A73A 4N0UD 1J7EA 4FIPB 3FWBC 4LB2A 1GNIA 3GQXA 2NQOA 4PO0A 5HOZA 5IIXA 1HK4A 5GINA 5IIHA 5ID7A 2DBWA 2E0XA 3TDLA 2LXTA 4BY9C 3GA9L 2KBZA 3KJLA 2BXHA 2QM6A 2Z8KA 1E7IA 4LA0A 4ZUXV 4FK5B 5DBYA 2XVWA 2XMOA 1TXUA 2ROHA 4JK4A 3UIVA 3LU7A 1MIWA 3LU8A 2BXGA 3WHQA 3G9KD 1BKEA 4F5UA 3H37A 1MM8A 3B9MA 4ZBKA
chains in the Genus database with same CATH topology

5IJ5A 1HK5A 1UORA 2BXBA 2XVVA 2LOQA 2DYMA 1H5WA 2BXAA 2BXDA 2QHBA 4FJCB 5GIPA 5IJEA 3MHSB 3H3AA 1MIVA 1HA2A 4G03A 4W4UB 5ID9A 1KXPD 4ZCGA 1J78A 1AO6A 3NVKA 3B9LA 4L9QA 4N0FD 3V09A 1LNSA 4N3ZA 4F5SA 2OZBB 4J2VA 2QMCA 2YDFA 5DQFA 1IJGA 2XW1A 4S1YA 3NVIA 1H9ZA 3VQIA 4GDLB 2XVQA 4GDXA 2BXEA 1E7BA 5B5TA 4ZBRA 1MA9A 3GQUA 4IW2A 5GIOA 2BXOA 5IIUA 1BM0A 2BXCA 4LUFA 5IFOA 5BPKA 2JUHA 3FNMA 4IW1A 4EMXA 2BXFA 2I2ZA 2DG5A 1BJ5A 1HK2A 2AJEA 4DHXB 5FUOA 1LOTA 4G04A 2OT3A 2DBUA 5GHKA 3ICXA 3LU6A 3CX9A 2DBXA 4E99A 2VDBA 4NAWB 2EFCA 3KIKA 4TQ1A 4BKEA 4TQ0A 3SIVB 2Z8IA 4K2CA 1JNBA 1E7GA 4C31B 1FOUA 1E78A 2XVUA 2BXKA 1E7AA 4HGKA 4L8UA 3M99C 3V03A 3WHRA 3WHSA 3V08A 2BXPA 2BX8A 3NMUA 4M70B 2DYOA 4Z69A 3SQJA 4WA6B 4K71A 4LB9A 1GNJA 1E7EA 2EFEA 2V36A 2XW0A 3A75A 3NVMA 2CKXA 3W1SA 4F5VA 5IJFA 2EFDA 1VFIA 2EFHA 5D7GA 1E7CA 4L9KA 4LUHA 4G01A 3MHHB 4F5TA 1O9XA 4GDKB 4OR0A 2BXLA 4GG2A 2BXNA 2BXQA 2XSIA 4HGMB 4MBEC 4OTTA 4PO0A 1E7FA 2BXMA 3FWCC 2NNWA 3JRYA 2E0YA 4OTUA 2Z8JA 4Z9OA 3PLAA 4ZC6A 1TF0A 1VZSA 4ZBQA 3JQZA 2I30A 1MIYA 2VUFA 1NT2B 1HK3A 1KW2A 1E7HA 4OT2A 2VUEA 3SIUB 1N5UA 2BXIA 1HK1A 3A73A 4N0UD 1J7EA 4FIPB 3FWBC 4LB2A 1GNIA 3GQXA 2NQOA 5HOZA 5IIXA 1HK4A 5GINA 5IIHA 5ID7A 2DBWA 2E0XA 3TDLA 4BY9C 3GA9L 2KBZA 3KJLA 2BXHA 2QM6A 2Z8KA 1E7IA 4LA0A 4ZUXV 4FK5B 5DBYA 2XVWA 2XMOA 1TXUA 2ROHA 4JK4A 3UIVA 3LU7A 1MIWA 3LU8A 2BXGA 3WHQA 3G9KD 1BKEA 4F5UA 3H37A 3B9MA 4ZBKA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 5IJ5 A;  1HK5 A;  1UOR A;  2BXB A;  2XVV A;  2BXA A;  2BXD A;  5IJE A;  4G03 A;  1HA2 A;  5ID9 A;  1KXP D;  1J78 A;  1AO6 A;  3B9L A;  4L9Q A;  4N0F D;  3V09 A;  4F5S A;  4J2V A;  2YDF A;  5DQF A;  2XW1 A;  4S1Y A;  1H9Z A;  2XVQ A;  2BXE A;  1E7B A;  4ZBR A;  1MA9 A;  4IW2 A;  2BXO A;  5IIU A;  1BM0 A;  2BXC A;  4LUF A;  5IFO A;  4IW1 A;  4EMX A;  2BXF A;  2I2Z A;  1BJ5 A;  1HK2 A;  5FUO A;  1LOT A;  4G04 A;  5GHK A;  3LU6 A;  3CX9 A;  4E99 A;  2VDB A;  4BKE A;  4K2C A;  1E7G A;  1E78 A;  2XVU A;  2BXK A;  1E7A A;  4HGK A;  4L8U A;  3V03 A;  3V08 A;  2BXP A;  2BX8 A;  4Z69 A;  3SQJ A;  4K71 A;  4LB9 A;  1GNJ A;  1E7E A;  2XW0 A;  4F5V A;  5IJF A;  1E7C A;  4L9K A;  4LUH A;  4F5T A;  1O9X A;  4OR0 A;  2BXL A;  4PO0 A;  2BXN A;  2BXQ A;  2XSI A;  4HGM B;  1E7F A;  2BXM A;  3JRY A;  1TF0 A;  4ZBQ A;  3JQZ A;  2I30 A;  2VUF A;  1HK3 A;  1KW2 A;  1E7H A;  4OT2 A;  2VUE A;  1N5U A;  2BXI A;  1HK1 A;  3A73 A;  4N0U D;  1J7E A;  4LB2 A;  5HOZ A;  1GNI A;  5IIX A;  1HK4 A;  5IIH A;  5ID7 A;  3TDL A;  2BXH A;  4LA0 A;  1E7I A;  5DBY A;  2XVW A;  4JK4 A;  3UIV A;  3LU7 A;  3LU8 A;  2BXG A;  1BKE A;  4F5U A;  3B9M A; 
#chains in the Genus database with same CATH topology
 5IJ5 A;  1HK5 A;  1MUH A;  1UOR A;  2BXB A;  2XVV A;  2LOQ A;  2DYM A;  1H5W A;  2BXA A;  2BXD A;  4D7X A;  1KDX A;  2QHB A;  4FJC B;  5GIP A;  5IJE A;  3MHS B;  3H3A A;  1MIV A;  1HA2 A;  4G03 A;  4W4U B;  5ID9 A;  1KXP D;  4ZCG A;  1J78 A;  1AO6 A;  3NVK A;  3B9L A;  4L9Q A;  4N0F D;  3V09 A;  1LNS A;  4N3Z A;  4F5S A;  2OZB B;  4J2V A;  2QMC A;  2YDF A;  5DQF A;  1IJG A;  2XW1 A;  3BPJ A;  4S1Y A;  1H9Z A;  3VQI A;  3NVI A;  4GDL B;  2XVQ A;  4GDX A;  2BXE A;  1E7B A;  5B5T A;  4ZBR A;  1MA9 A;  3GQU A;  4IW2 A;  5GIO A;  2BXO A;  5IIU A;  1BM0 A;  2GUT A;  2BXC A;  4LUF A;  5IFO A;  5BPK A;  2JUH A;  3FNM A;  4IW1 A;  3ECP A;  4DM0 A;  4EMX A;  2BXF A;  2I2Z A;  2DG5 A;  1BJ5 A;  1HK2 A;  2AJE A;  4DHX B;  5FUO A;  1LOT A;  4G04 A;  2OT3 A;  2DBU A;  5GHK A;  3ICX A;  3LU6 A;  3CX9 A;  2DBX A;  4E99 A;  2VDB A;  4NAW B;  2EFC A;  3KIK A;  4TQ1 A;  4BKE A;  4TQ0 A;  3SIV B;  2AGH B;  2Z8I A;  4I9O A;  4K2C A;  1JNB A;  1E7G A;  4C31 B;  1FOU A;  1E78 A;  2XVU A;  2BXK A;  1E7A A;  4HGK A;  4L8U A;  3M99 C;  3V03 A;  3WHR A;  3WHS A;  3V08 A;  2BXP A;  2BX8 A;  3NMU A;  4M70 B;  2DYO A;  4Z69 A;  2LQI A;  4WA6 B;  3SQJ A;  4K71 A;  4LB9 A;  1GNJ A;  1E7E A;  2EFE A;  2V36 A;  2XW0 A;  3A75 A;  3NVM A;  2CKX A;  2K0N A;  3W1S A;  4F5V A;  5IJF A;  2EFD A;  1VFI A;  2EFH A;  5D7G A;  4OR0 A;  1E7C A;  4L9K A;  4LUH A;  4G01 A;  3MHH B;  4F5T A;  1O9X A;  4GDK B;  2KWF A;  2BXL A;  4GG2 A;  2BXN A;  2BXQ A;  2XSI A;  2LQH A;  4HGM B;  4MBE C;  4OTT A;  1E7F A;  2BXM A;  3FWC C;  2NNW A;  3JRY A;  2E0Y A;  4OTU A;  2Z8J A;  4Z9O A;  3PLA A;  4ZC6 A;  1TF0 A;  1VZS A;  4ZBQ A;  3JQZ A;  1MUS A;  1SB0 A;  2I30 A;  1MIY A;  2VUF A;  2LXS A;  1NT2 B;  1HK3 A;  1KW2 A;  1E7H A;  4OT2 A;  2VUE A;  3SIU B;  1N5U A;  2BXI A;  1HK1 A;  3A73 A;  4N0U D;  1J7E A;  4FIP B;  3FWB C;  4LB2 A;  1GNI A;  3GQX A;  2NQO A;  4PO0 A;  5HOZ A;  5IIX A;  1HK4 A;  5GIN A;  5IIH A;  5ID7 A;  2DBW A;  2E0X A;  3TDL A;  2LXT A;  4BY9 C;  3GA9 L;  2KBZ A;  3KJL A;  2BXH A;  2QM6 A;  2Z8K A;  1E7I A;  4LA0 A;  4ZUX V;  4FK5 B;  5DBY A;  2XVW A;  2XMO A;  1TXU A;  2ROH A;  4JK4 A;  3UIV A;  3LU7 A;  1MIW A;  3LU8 A;  2BXG A;  3WHQ A;  3G9K D;  1BKE A;  4F5U A;  3H37 A;  1MM8 A;  3B9M A;  4ZBK A; 
#chains in the Genus database with same CATH homology
 5IJ5 A;  1HK5 A;  1UOR A;  2BXB A;  2XVV A;  2LOQ A;  2DYM A;  1H5W A;  2BXA A;  2BXD A;  2QHB A;  4FJC B;  5GIP A;  5IJE A;  3MHS B;  3H3A A;  1MIV A;  1HA2 A;  4G03 A;  4W4U B;  5ID9 A;  1KXP D;  4ZCG A;  1J78 A;  1AO6 A;  3NVK A;  3B9L A;  4L9Q A;  4N0F D;  3V09 A;  1LNS A;  4N3Z A;  4F5S A;  2OZB B;  4J2V A;  2QMC A;  2YDF A;  5DQF A;  1IJG A;  2XW1 A;  4S1Y A;  3NVI A;  1H9Z A;  3VQI A;  4GDL B;  2XVQ A;  4GDX A;  2BXE A;  1E7B A;  5B5T A;  4ZBR A;  1MA9 A;  3GQU A;  4IW2 A;  5GIO A;  2BXO A;  5IIU A;  1BM0 A;  2BXC A;  4LUF A;  5IFO A;  5BPK A;  2JUH A;  3FNM A;  4IW1 A;  4EMX A;  2BXF A;  2I2Z A;  2DG5 A;  1BJ5 A;  1HK2 A;  2AJE A;  4DHX B;  5FUO A;  1LOT A;  4G04 A;  2OT3 A;  2DBU A;  5GHK A;  3ICX A;  3LU6 A;  3CX9 A;  2DBX A;  4E99 A;  2VDB A;  4NAW B;  2EFC A;  3KIK A;  4TQ1 A;  4BKE A;  4TQ0 A;  3SIV B;  2Z8I A;  4K2C A;  1JNB A;  1E7G A;  4C31 B;  1FOU A;  1E78 A;  2XVU A;  2BXK A;  1E7A A;  4HGK A;  4L8U A;  3M99 C;  3V03 A;  3WHR A;  3WHS A;  3V08 A;  2BXP A;  2BX8 A;  3NMU A;  4M70 B;  2DYO A;  4Z69 A;  3SQJ A;  4WA6 B;  4K71 A;  4LB9 A;  1GNJ A;  1E7E A;  2EFE A;  2V36 A;  2XW0 A;  3A75 A;  3NVM A;  2CKX A;  3W1S A;  4F5V A;  5IJF A;  2EFD A;  1VFI A;  2EFH A;  5D7G A;  1E7C A;  4L9K A;  4LUH A;  4G01 A;  3MHH B;  4F5T A;  1O9X A;  4GDK B;  4OR0 A;  2BXL A;  4GG2 A;  2BXN A;  2BXQ A;  2XSI A;  4HGM B;  4MBE C;  4OTT A;  4PO0 A;  1E7F A;  2BXM A;  3FWC C;  2NNW A;  3JRY A;  2E0Y A;  4OTU A;  2Z8J A;  4Z9O A;  3PLA A;  4ZC6 A;  1TF0 A;  1VZS A;  4ZBQ A;  3JQZ A;  2I30 A;  1MIY A;  2VUF A;  1NT2 B;  1HK3 A;  1KW2 A;  1E7H A;  4OT2 A;  2VUE A;  3SIU B;  1N5U A;  2BXI A;  1HK1 A;  3A73 A;  4N0U D;  1J7E A;  4FIP B;  3FWB C;  4LB2 A;  1GNI A;  3GQX A;  2NQO A;  5HOZ A;  5IIX A;  1HK4 A;  5GIN A;  5IIH A;  5ID7 A;  2DBW A;  2E0X A;  3TDL A;  4BY9 C;  3GA9 L;  2KBZ A;  3KJL A;  2BXH A;  2QM6 A;  2Z8K A;  1E7I A;  4LA0 A;  4ZUX V;  4FK5 B;  5DBY A;  2XVW A;  2XMO A;  1TXU A;  2ROH A;  4JK4 A;  3UIV A;  3LU7 A;  1MIW A;  3LU8 A;  2BXG A;  3WHQ A;  3G9K D;  1BKE A;  4F5U A;  3H37 A;  3B9M A;  4ZBK A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2BXCA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations