2BXD | Genus

Total Genus 214

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	214
sequence length	578
structure length	578
Chain Sequence	SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transport protein
source organism	Homo sapiens
publication title	Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	214
structure length	578
sequence length	578
chains with identical sequence	B
ec nomenclature
pdb deposition date	2005-07-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxdA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxdA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxdA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxdA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxdA06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxdA05

4LB2A 3TDLA 4LUHA 1HK1A 3B9LA 4ZBQA 4LUFA 5IJEA 1E78A 2BXPA 1HK4A 1E7IA 4J2VA 5IIHA 5DBYA 3SQJA 4N0FD 1J78A 2BX8A 1O9XA 5IIUA 2BXKA 4LA0A 2XVVA 1AO6A 2VDBA 3JQZA 4F5SA 4F5VA 4G03A 3LU8A 1KW2A 1GNJA 4IW2A 2BXCA 4N0UD 2XVUA 3LU7A 4PO0A 3LU6A 4OR0A 4L9QA 5FUOA 1BJ5A 2BXIA 1BKEA 4G04A 1GNIA 1H9ZA 4K2CA 2BXEA 5IIXA 4F5UA 2I2ZA 1E7HA 3A73A 2XVQA 5GHKA 1E7CA 1UORA 4F5TA 1E7BA 2XW0A 4E99A 1MA9A 1J7EA 1E7GA 2XVWA 4BKEA 4OT2A 1HK5A 4EMXA 2BXOA 1KXPD 2BXHA 1E7AA 3B9MA 2BXLA 2BXGA 1LOTA 4LB9A 3V09A 2VUEA 4ZBRA 4Z69A 2BXDA 4JK4A 2BXNA 3CX9A 5ID9A 4IW1A 4L8UA 1E7EA 2XW1A 2BXMA 5ID7A 4K71A 4L9KA 3V03A 1HA2A 2YDFA 3JRYA 5IJ5A 1BM0A 5IJFA 4HGMB 2I30A 5IFOA 1E7FA 2BXQA 3UIVA 1HK3A 1TF0A 2XSIA 1HK2A 5DQFA 5HOZA 2VUFA 4S1YA 2BXFA 4HGKA 1N5UA 2BXAA 3V08A 2BXBA
chains in the Genus database with same CATH superfamily

4OTUA 2CKXA 2EFHA 2LQHA 4LB2A 3TDLA 4LUHA 4ZC6A 1HK1A 4C31B 3B9LA 3MHSB 2DBUA 2OT3A 4ZBQA 4LUFA 5IJEA 1E78A 2BXPA 1HK4A 2DBWA 2EFDA 1E7IA 4J2VA 2QHBA 2DYOA 5IIHA 1MM8A 5DBYA 3SQJA 4MBEC 4N0FD 1J78A 2BX8A 1O9XA 4GDKB 5IIUA 1IJGA 2BXKA 3KJLA 4LA0A 2XVVA 1AO6A 3H37A 2VDBA 4WA6B 3JQZA 4F5SA 4F5VA 4GG2A 4G03A 3LU8A 1KW2A 3SIUB 1GNJA 4IW2A 2BXCA 4N0UD 3GA9L 4Z9OA 2XVUA 2Z8IA 3LU7A 4PO0A 2V36A 3LU6A 4OR0A 4L9QA 4ZBKA 1BJ5A 5FUOA 2BXIA 1KDXA 1BKEA 2Z8KA 3M99C 4G04A 1GNIA 1H9ZA 4K2CA 4M70B 2BXEA 2K0NA 5BPKA 4N3ZA 5IIXA 2XMOA 4F5UA 5B5TA 2I2ZA 1E7HA 3A73A 1NT2B 2NQOA 4I9OA 2XVQA 1MUSA 2JUHA 5GHKA 2EFEA 1E7CA 1UORA 1MIWA 1MUHA 2NNWA 4FK5B 3KIKA 4DM0A 2EFCA 1E7BA 1VZSA 4D7XA 4F5TA 3ECPA 3GQXA 4ZUXV 2KBZA 2XW0A 4E99A 5GIOA 1MA9A 3WHRA 2DYMA 1J7EA 1E7GA 2XVWA 4DHXB 4BKEA 3NVIA 3BPJA 3FWBC 4OT2A 1HK5A 2DBXA 3NVMA 2BXOA 1KXPD 4EMXA 2BXHA 3VQIA 1E7AA 1H5WA 3B9MA 2LOQA 3G9KD 3NVKA 2BXLA 2BXGA 1LOTA 2QMCA 4BY9C 4LB9A 2QM6A 3V09A 4G01A 4TQ1A 1MIVA 2VUEA 4ZBRA 1SB0A 4Z69A 2BXDA 4FJCB 4JK4A 3GQUA 2BXNA 5GIPA 2OZBB 3CX9A 2DG5A 5ID9A 4IW1A 5D7GA 4L8UA 4GDLB 1E7EA 2XW1A 4TQ0A 2BXMA 3FNMA 2ROHA 4GDXA 4NAWB 5ID7A 3H3AA 1FOUA 4K71A 1VFIA 2AGHB 4L9KA 3V03A 3WHQA 2AJEA 3SIVB 1HA2A 2YDFA 3W1SA 2LQIA 3ICXA 3JRYA 3A75A 5IJ5A 3MHHB 2KWFA 1BM0A 4ZCGA 5IJFA 4HGMB 2GUTA 2I30A 3PLAA 2Z8JA 5IFOA 4FIPB 1E7FA 2BXQA 4W4UB 3UIVA 3FWCC 4OTTA 1HK3A 2LXTA 1TF0A 2XSIA 1JNBA 1HK2A 1MIYA 5DQFA 5HOZA 2VUFA 4S1YA 2E0XA 3WHSA 2BXFA 2LXSA 4HGKA 1LNSA 1N5UA 3NMUA 2BXAA 2E0YA 3V08A 5GINA 1TXUA 2BXBA
chains in the Genus database with same CATH topology

4OTUA 2CKXA 2EFHA 4LB2A 3TDLA 4LUHA 4ZC6A 1HK1A 4C31B 3B9LA 3MHSB 2DBUA 2OT3A 4ZBQA 4LUFA 5IJEA 1E78A 2BXPA 1HK4A 2DBWA 2EFDA 1E7IA 4J2VA 2QHBA 2DYOA 5IIHA 5DBYA 3SQJA 4MBEC 4N0FD 1J78A 2BX8A 1O9XA 4GDKB 5IIUA 1IJGA 2BXKA 3KJLA 4LA0A 2XVVA 1AO6A 3H37A 2VDBA 4WA6B 3JQZA 4F5SA 4F5VA 4GG2A 4G03A 3LU8A 1KW2A 3SIUB 1GNJA 4IW2A 2BXCA 4N0UD 3GA9L 4Z9OA 2XVUA 2Z8IA 3LU7A 4PO0A 2V36A 3LU6A 4OR0A 4L9QA 4ZBKA 1BJ5A 5FUOA 2BXIA 1BKEA 2Z8KA 3M99C 4G04A 1GNIA 1H9ZA 4K2CA 4M70B 2BXEA 5BPKA 4N3ZA 5IIXA 2XMOA 4F5UA 5B5TA 2I2ZA 1E7HA 3A73A 1NT2B 2NQOA 2XVQA 2JUHA 5GHKA 2EFEA 1E7CA 1UORA 1MIWA 2NNWA 4FK5B 3KIKA 2EFCA 1E7BA 1VZSA 4F5TA 3GQXA 4ZUXV 2KBZA 2XW0A 4E99A 5GIOA 1MA9A 3WHRA 2DYMA 1J7EA 1E7GA 2XVWA 4DHXB 4BKEA 3NVIA 3FWBC 4OT2A 1HK5A 2DBXA 3NVMA 2BXOA 1KXPD 4EMXA 2BXHA 3VQIA 1E7AA 1H5WA 3B9MA 2LOQA 3G9KD 3NVKA 2BXLA 2BXGA 1LOTA 2QMCA 4BY9C 4LB9A 2QM6A 3V09A 4G01A 4TQ1A 1MIVA 2VUEA 4ZBRA 4Z69A 2BXDA 4FJCB 4JK4A 3GQUA 2BXNA 5GIPA 2OZBB 3CX9A 2DG5A 5ID9A 4IW1A 5D7GA 4L8UA 4GDLB 1E7EA 2XW1A 4TQ0A 2BXMA 3FNMA 2ROHA 4GDXA 4NAWB 5ID7A 3H3AA 1FOUA 4K71A 1VFIA 4L9KA 3V03A 3WHQA 2AJEA 3SIVB 1HA2A 2YDFA 3W1SA 3ICXA 3JRYA 3A75A 5IJ5A 3MHHB 1BM0A 4ZCGA 5IJFA 4HGMB 2I30A 3PLAA 2Z8JA 5IFOA 4FIPB 1E7FA 2BXQA 4W4UB 3UIVA 3FWCC 4OTTA 1HK3A 1TF0A 2XSIA 1JNBA 1HK2A 1MIYA 5DQFA 5HOZA 2VUFA 4S1YA 2E0XA 3WHSA 2BXFA 4HGKA 1LNSA 1N5UA 3NMUA 2BXAA 2E0YA 3V08A 5GINA 1TXUA 2BXBA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4LB2 A;  3TDL A;  4LUH A;  1HK1 A;  3B9L A;  4ZBQ A;  4LUF A;  5IJE A;  1E78 A;  2BXP A;  1HK4 A;  1E7I A;  4J2V A;  5IIH A;  5DBY A;  3SQJ A;  4N0F D;  1J78 A;  2BX8 A;  1O9X A;  5IIU A;  2BXK A;  4LA0 A;  2XVV A;  1AO6 A;  2VDB A;  3JQZ A;  4F5S A;  4F5V A;  4G03 A;  3LU8 A;  1KW2 A;  1GNJ A;  4IW2 A;  2BXC A;  4N0U D;  2XVU A;  3LU7 A;  4PO0 A;  3LU6 A;  4OR0 A;  4L9Q A;  5FUO A;  1BJ5 A;  2BXI A;  1BKE A;  4G04 A;  1GNI A;  1H9Z A;  4K2C A;  2BXE A;  5IIX A;  4F5U A;  2I2Z A;  1E7H A;  3A73 A;  2XVQ A;  5GHK A;  1E7C A;  1UOR A;  4F5T A;  1E7B A;  2XW0 A;  4E99 A;  1MA9 A;  1J7E A;  1E7G A;  2XVW A;  4BKE A;  4OT2 A;  1HK5 A;  4EMX A;  2BXO A;  1KXP D;  2BXH A;  1E7A A;  3B9M A;  2BXL A;  2BXG A;  1LOT A;  4LB9 A;  3V09 A;  2VUE A;  4ZBR A;  4Z69 A;  2BXD A;  4JK4 A;  2BXN A;  3CX9 A;  5ID9 A;  4IW1 A;  4L8U A;  1E7E A;  2XW1 A;  2BXM A;  5ID7 A;  4K71 A;  4L9K A;  3V03 A;  1HA2 A;  2YDF A;  3JRY A;  5IJ5 A;  1BM0 A;  5IJF A;  4HGM B;  2I30 A;  5IFO A;  1E7F A;  2BXQ A;  3UIV A;  1HK3 A;  1TF0 A;  2XSI A;  1HK2 A;  5DQF A;  5HOZ A;  2VUF A;  4S1Y A;  2BXF A;  4HGK A;  1N5U A;  2BXA A;  3V08 A;  2BXB A; 
#chains in the Genus database with same CATH topology
 4OTU A;  2CKX A;  2EFH A;  2LQH A;  4LB2 A;  3TDL A;  4LUH A;  4ZC6 A;  1HK1 A;  4C31 B;  3B9L A;  3MHS B;  2DBU A;  2OT3 A;  4ZBQ A;  4LUF A;  5IJE A;  1E78 A;  2BXP A;  1HK4 A;  2DBW A;  2EFD A;  1E7I A;  4J2V A;  2QHB A;  2DYO A;  5IIH A;  1MM8 A;  5DBY A;  3SQJ A;  4MBE C;  4N0F D;  1J78 A;  2BX8 A;  1O9X A;  4GDK B;  5IIU A;  1IJG A;  2BXK A;  3KJL A;  4LA0 A;  2XVV A;  1AO6 A;  3H37 A;  2VDB A;  4WA6 B;  3JQZ A;  4F5S A;  4F5V A;  4GG2 A;  4G03 A;  3LU8 A;  1KW2 A;  3SIU B;  1GNJ A;  4IW2 A;  2BXC A;  4N0U D;  3GA9 L;  4Z9O A;  2XVU A;  2Z8I A;  3LU7 A;  4PO0 A;  2V36 A;  3LU6 A;  4OR0 A;  4L9Q A;  4ZBK A;  1BJ5 A;  5FUO A;  2BXI A;  1KDX A;  1BKE A;  2Z8K A;  3M99 C;  4G04 A;  1GNI A;  1H9Z A;  4K2C A;  4M70 B;  2BXE A;  2K0N A;  5BPK A;  4N3Z A;  5IIX A;  2XMO A;  4F5U A;  5B5T A;  2I2Z A;  1E7H A;  3A73 A;  1NT2 B;  2NQO A;  4I9O A;  2XVQ A;  1MUS A;  2JUH A;  5GHK A;  2EFE A;  1E7C A;  1UOR A;  1MIW A;  1MUH A;  2NNW A;  4FK5 B;  3KIK A;  4DM0 A;  2EFC A;  1E7B A;  1VZS A;  4D7X A;  4F5T A;  3ECP A;  3GQX A;  4ZUX V;  2KBZ A;  2XW0 A;  4E99 A;  5GIO A;  1MA9 A;  3WHR A;  2DYM A;  1J7E A;  1E7G A;  2XVW A;  4DHX B;  4BKE A;  3NVI A;  3BPJ A;  3FWB C;  4OT2 A;  1HK5 A;  2DBX A;  3NVM A;  2BXO A;  1KXP D;  4EMX A;  2BXH A;  3VQI A;  1E7A A;  1H5W A;  3B9M A;  2LOQ A;  3G9K D;  3NVK A;  2BXL A;  2BXG A;  1LOT A;  2QMC A;  4BY9 C;  4LB9 A;  2QM6 A;  3V09 A;  4G01 A;  4TQ1 A;  1MIV A;  2VUE A;  4ZBR A;  1SB0 A;  4Z69 A;  2BXD A;  4FJC B;  4JK4 A;  3GQU A;  2BXN A;  5GIP A;  2OZB B;  3CX9 A;  2DG5 A;  5ID9 A;  4IW1 A;  5D7G A;  4L8U A;  4GDL B;  1E7E A;  2XW1 A;  4TQ0 A;  2BXM A;  3FNM A;  2ROH A;  4GDX A;  4NAW B;  5ID7 A;  3H3A A;  1FOU A;  4K71 A;  1VFI A;  2AGH B;  4L9K A;  3V03 A;  3WHQ A;  2AJE A;  3SIV B;  1HA2 A;  2YDF A;  3W1S A;  2LQI A;  3ICX A;  3JRY A;  3A75 A;  5IJ5 A;  3MHH B;  2KWF A;  1BM0 A;  4ZCG A;  5IJF A;  4HGM B;  2GUT A;  2I30 A;  3PLA A;  2Z8J A;  5IFO A;  4FIP B;  1E7F A;  2BXQ A;  4W4U B;  3UIV A;  3FWC C;  4OTT A;  1HK3 A;  2LXT A;  1TF0 A;  2XSI A;  1JNB A;  1HK2 A;  1MIY A;  5DQF A;  5HOZ A;  2VUF A;  4S1Y A;  2E0X A;  3WHS A;  2BXF A;  2LXS A;  4HGK A;  1LNS A;  1N5U A;  3NMU A;  2BXA A;  2E0Y A;  3V08 A;  5GIN A;  1TXU A;  2BXB A; 
#chains in the Genus database with same CATH homology
 4OTU A;  2CKX A;  2EFH A;  4LB2 A;  3TDL A;  4LUH A;  4ZC6 A;  1HK1 A;  4C31 B;  3B9L A;  3MHS B;  2DBU A;  2OT3 A;  4ZBQ A;  4LUF A;  5IJE A;  1E78 A;  2BXP A;  1HK4 A;  2DBW A;  2EFD A;  1E7I A;  4J2V A;  2QHB A;  2DYO A;  5IIH A;  5DBY A;  3SQJ A;  4MBE C;  4N0F D;  1J78 A;  2BX8 A;  1O9X A;  4GDK B;  5IIU A;  1IJG A;  2BXK A;  3KJL A;  4LA0 A;  2XVV A;  1AO6 A;  3H37 A;  2VDB A;  4WA6 B;  3JQZ A;  4F5S A;  4F5V A;  4GG2 A;  4G03 A;  3LU8 A;  1KW2 A;  3SIU B;  1GNJ A;  4IW2 A;  2BXC A;  4N0U D;  3GA9 L;  4Z9O A;  2XVU A;  2Z8I A;  3LU7 A;  4PO0 A;  2V36 A;  3LU6 A;  4OR0 A;  4L9Q A;  4ZBK A;  1BJ5 A;  5FUO A;  2BXI A;  1BKE A;  2Z8K A;  3M99 C;  4G04 A;  1GNI A;  1H9Z A;  4K2C A;  4M70 B;  2BXE A;  5BPK A;  4N3Z A;  5IIX A;  2XMO A;  4F5U A;  5B5T A;  2I2Z A;  1E7H A;  3A73 A;  1NT2 B;  2NQO A;  2XVQ A;  2JUH A;  5GHK A;  2EFE A;  1E7C A;  1UOR A;  1MIW A;  2NNW A;  4FK5 B;  3KIK A;  2EFC A;  1E7B A;  1VZS A;  4F5T A;  3GQX A;  4ZUX V;  2KBZ A;  2XW0 A;  4E99 A;  5GIO A;  1MA9 A;  3WHR A;  2DYM A;  1J7E A;  1E7G A;  2XVW A;  4DHX B;  4BKE A;  3NVI A;  3FWB C;  4OT2 A;  1HK5 A;  2DBX A;  3NVM A;  2BXO A;  1KXP D;  4EMX A;  2BXH A;  3VQI A;  1E7A A;  1H5W A;  3B9M A;  2LOQ A;  3G9K D;  3NVK A;  2BXL A;  2BXG A;  1LOT A;  2QMC A;  4BY9 C;  4LB9 A;  2QM6 A;  3V09 A;  4G01 A;  4TQ1 A;  1MIV A;  2VUE A;  4ZBR A;  4Z69 A;  2BXD A;  4FJC B;  4JK4 A;  3GQU A;  2BXN A;  5GIP A;  2OZB B;  3CX9 A;  2DG5 A;  5ID9 A;  4IW1 A;  5D7G A;  4L8U A;  4GDL B;  1E7E A;  2XW1 A;  4TQ0 A;  2BXM A;  3FNM A;  2ROH A;  4GDX A;  4NAW B;  5ID7 A;  3H3A A;  1FOU A;  4K71 A;  1VFI A;  4L9K A;  3V03 A;  3WHQ A;  2AJE A;  3SIV B;  1HA2 A;  2YDF A;  3W1S A;  3ICX A;  3JRY A;  3A75 A;  5IJ5 A;  3MHH B;  1BM0 A;  4ZCG A;  5IJF A;  4HGM B;  2I30 A;  3PLA A;  2Z8J A;  5IFO A;  4FIP B;  1E7F A;  2BXQ A;  4W4U B;  3UIV A;  3FWC C;  4OTT A;  1HK3 A;  1TF0 A;  2XSI A;  1JNB A;  1HK2 A;  1MIY A;  5DQF A;  5HOZ A;  2VUF A;  4S1Y A;  2E0X A;  3WHS A;  2BXF A;  4HGK A;  1LNS A;  1N5U A;  3NMU A;  2BXA A;  2E0Y A;  3V08 A;  5GIN A;  1TXU A;  2BXB A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2BXDA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations