2BXHA

Human serum albumin complexed with indoxyl sulfate
Total Genus 206
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
206
sequence length
557
structure length
557
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 206
structure length 557
sequence length 557
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA05
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA06
5IIUA 2BXHA 3V08A 4Z69A 2BXFA 1UORA 3V03A 4LA0A 5GHKA 4HGMB 1J78A 1E7FA 2BXPA 3LU7A 2BXLA 5DBYA 2BX8A 4IW1A 2XVQA 4OT2A 5ID7A 4F5SA 4BKEA 1BM0A 2BXBA 1E7GA 4F5TA 2XVUA 1GNJA 4N0FD 5DQFA 4F5VA 1TF0A 2BXKA 2I30A 4LUHA 1HK3A 1AO6A 3CX9A 4F5UA 2BXAA 1KW2A 2BXGA 2BXOA 4ZBQA 1H9ZA 3A73A 4N0UD 4J2VA 2VDBA 4PO0A 3B9LA 2YDFA 2XW0A 1KXPD 1E7HA 2BXMA 2VUEA 1HK2A 1HA2A 1J7EA 1E7IA 4E99A 2BXIA 4ZBRA 2VUFA 4L8UA 4LB9A 2BXQA 1BKEA 5IIXA 4IW2A 5IJFA 2BXEA 5IJEA 2BXCA 1E7AA 4EMXA 2I2ZA 1HK5A 3LU6A 5IIHA 1E7EA 5IFOA 2XSIA 3B9MA 2XVVA 2BXDA 4S1YA 5HOZA 1E78A 1LOTA 1E7CA 1O9XA 1E7BA 2XW1A 4G04A 1HK1A 3UIVA 4L9QA 1BJ5A 3SQJA 1N5UA 4L9KA 4LUFA 3JRYA 4OR0A 3V09A 2XVWA 5IJ5A 3LU8A 5ID9A 5FUOA 4LB2A 4HGKA 4K2CA 4JK4A 2BXNA 3JQZA 3TDLA 4G03A 1GNIA 1HK4A 1MA9A 4K71A
chains in the Genus database with same CATH superfamily
4TQ0A 5IIUA 5GIPA 2BXHA 1JNBA 3GA9L 3V08A 4Z69A 3NVMA 4ZBKA 2EFEA 2BXFA 1UORA 2NQOA 4ZUXV 2DYOA 3V03A 4LA0A 2V36A 4N3ZA 5GHKA 3FWBC 3A75A 4HGMB 3VQIA 1J78A 1E7FA 2BXPA 3LU7A 4OTUA 2BXLA 2CKXA 2LXTA 2BX8A 5DBYA 2DYMA 2EFDA 4IW1A 2XVQA 1MIWA 4OT2A 5ID7A 2K0NA 4F5SA 4BKEA 1SB0A 1BM0A 4NAWB 4WA6B 2BXBA 1E7GA 4DHXB 4F5TA 2XVUA 1H5WA 1GNJA 2AGHB 4N0FD 5DQFA 4F5VA 1TF0A 4M70B 3ECPA 4I9OA 2BXKA 1TXUA 3PLAA 4C31B 2I30A 4LUHA 1HK3A 2Z8KA 4FJCB 4D7XA 1AO6A 4FK5B 3CX9A 3KIKA 2XMOA 3GQUA 4F5UA 4MBEC 2BXAA 2ROHA 2Z8JA 1KW2A 5B5TA 2QM6A 2BXGA 2BXOA 4ZBQA 3NMUA 4GDXA 1H9ZA 3A73A 4N0UD 4J2VA 3WHRA 3M99C 2LQHA 2VDBA 4PO0A 1VFIA 4FIPB 3B9LA 2YDFA 2XW0A 3ICXA 3H3AA 1KXPD 1E7HA 2BXMA 2VUEA 5GIOA 3FNMA 1HK2A 2OZBB 3MHSB 2E0XA 2E0YA 1HA2A 1VZSA 2GUTA 3WHSA 2JUHA 1J7EA 1E7IA 1FOUA 4E99A 2QHBA 2BXIA 3BPJA 3KJLA 4W4UB 4ZBRA 2VUFA 4L8UA 4LB9A 3NVIA 2KWFA 2BXQA 1BKEA 4BY9C 5IIXA 1KDXA 4IW2A 2OT3A 3SIVB 5IJFA 1LNSA 2BXEA 3FWCC 5IJEA 2BXCA 1MUHA 2DBUA 3H37A 3SIUB 3WHQA 1MUSA 1E7AA 5GINA 4EMXA 1NT2B 2I2ZA 1HK5A 3LU6A 5IIHA 1E7EA 5IFOA 2XSIA 5D7GA 3B9MA 2XVVA 2DBXA 1IJGA 2BXDA 4S1YA 5HOZA 2KBZA 2NNWA 5BPKA 1E78A 3W1SA 1LOTA 1E7CA 3GQXA 4DM0A 1O9XA 1E7BA 2XW1A 4GDKB 4G04A 1HK1A 4TQ1A 2LOQA 4ZC6A 4GG2A 3UIVA 4L9QA 4OTTA 1BJ5A 3SQJA 2DBWA 4Z9OA 1N5UA 4L9KA 2EFHA 3JRYA 4LUFA 2QMCA 4OR0A 3V09A 1MIYA 2DG5A 4G01A 2XVWA 3G9KD 5IJ5A 3LU8A 3MHHB 5ID9A 5FUOA 1MIVA 4LB2A 2LQIA 4HGKA 4K2CA 4JK4A 2BXNA 2Z8IA 2AJEA 2LXSA 3JQZA 3TDLA 3NVKA 4G03A 2EFCA 1GNIA 1HK4A 1MA9A 4ZCGA 1MM8A 4GDLB 4K71A
chains in the Genus database with same CATH topology
4TQ0A 5IIUA 5GIPA 2BXHA 1JNBA 3GA9L 3V08A 4Z69A 3NVMA 4ZBKA 2EFEA 2BXFA 1UORA 2NQOA 4ZUXV 2DYOA 3V03A 4LA0A 2V36A 4N3ZA 5GHKA 3FWBC 3A75A 4HGMB 3VQIA 1J78A 1E7FA 2BXPA 3LU7A 4OTUA 2BXLA 2CKXA 5DBYA 2BX8A 2DYMA 2EFDA 4IW1A 2XVQA 1MIWA 4OT2A 5ID7A 4F5SA 4BKEA 4NAWB 1BM0A 4WA6B 2BXBA 1E7GA 4DHXB 4F5TA 2XVUA 1H5WA 1GNJA 4N0FD 5DQFA 4F5VA 1TF0A 4M70B 2BXKA 1TXUA 3PLAA 4C31B 2I30A 4LUHA 1HK3A 2Z8KA 4FJCB 1AO6A 4FK5B 3CX9A 3KIKA 2XMOA 3GQUA 4F5UA 4MBEC 2BXAA 2ROHA 2Z8JA 1KW2A 5B5TA 2QM6A 2BXGA 2BXOA 4ZBQA 3NMUA 4GDXA 1H9ZA 3A73A 4N0UD 4J2VA 3WHRA 3M99C 2VDBA 4PO0A 1VFIA 4FIPB 3B9LA 2YDFA 2XW0A 3ICXA 3H3AA 1KXPD 1E7HA 2BXMA 2VUEA 5GIOA 3FNMA 1HK2A 2OZBB 3MHSB 2E0XA 2E0YA 1HA2A 1VZSA 3WHSA 2JUHA 1J7EA 1E7IA 1FOUA 4E99A 2QHBA 2BXIA 3KJLA 4W4UB 4ZBRA 2VUFA 4L8UA 4LB9A 3NVIA 2BXQA 1BKEA 4BY9C 5IIXA 4IW2A 2OT3A 3SIVB 5IJFA 1LNSA 2BXEA 3FWCC 5IJEA 2BXCA 3SIUB 2DBUA 3H37A 3WHQA 1E7AA 5GINA 4EMXA 1NT2B 2I2ZA 1HK5A 3LU6A 5IIHA 1E7EA 5IFOA 2XSIA 5D7GA 3B9MA 2XVVA 2DBXA 1IJGA 2BXDA 4S1YA 5HOZA 2KBZA 2NNWA 5BPKA 1E78A 3W1SA 1LOTA 1E7CA 3GQXA 1O9XA 1E7BA 2XW1A 4GDKB 4G04A 1HK1A 4TQ1A 2LOQA 4ZC6A 4GG2A 3UIVA 4L9QA 4OTTA 1BJ5A 3SQJA 2DBWA 4Z9OA 1N5UA 4L9KA 2EFHA 3JRYA 4LUFA 2QMCA 4OR0A 3V09A 1MIYA 2DG5A 4G01A 2XVWA 3G9KD 5IJ5A 3LU8A 3MHHB 5ID9A 5FUOA 1MIVA 4LB2A 4HGKA 4K2CA 4JK4A 2BXNA 2Z8IA 2AJEA 3JQZA 3TDLA 3NVKA 4G03A 2EFCA 1GNIA 1HK4A 1MA9A 4ZCGA 4GDLB 4K71A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IIU A;  2BXH A;  3V08 A;  4Z69 A;  2BXF A;  1UOR A;  3V03 A;  4LA0 A;  5GHK A;  4HGM B;  1J78 A;  1E7F A;  2BXP A;  3LU7 A;  2BXL A;  5DBY A;  2BX8 A;  4IW1 A;  2XVQ A;  4OT2 A;  5ID7 A;  4F5S A;  4BKE A;  1BM0 A;  2BXB A;  1E7G A;  4F5T A;  2XVU A;  1GNJ A;  4N0F D;  5DQF A;  4F5V A;  1TF0 A;  2BXK A;  2I30 A;  4LUH A;  1HK3 A;  1AO6 A;  3CX9 A;  4F5U A;  2BXA A;  1KW2 A;  2BXG A;  2BXO A;  4ZBQ A;  1H9Z A;  3A73 A;  4N0U D;  4J2V A;  2VDB A;  4PO0 A;  3B9L A;  2YDF A;  2XW0 A;  1KXP D;  1E7H A;  2BXM A;  2VUE A;  1HK2 A;  1HA2 A;  1J7E A;  1E7I A;  4E99 A;  2BXI A;  4ZBR A;  2VUF A;  4L8U A;  4LB9 A;  2BXQ A;  1BKE A;  5IIX A;  4IW2 A;  5IJF A;  2BXE A;  5IJE A;  2BXC A;  1E7A A;  4EMX A;  2I2Z A;  1HK5 A;  3LU6 A;  5IIH A;  1E7E A;  5IFO A;  2XSI A;  3B9M A;  2XVV A;  2BXD A;  4S1Y A;  5HOZ A;  1E78 A;  1LOT A;  1E7C A;  1O9X A;  1E7B A;  2XW1 A;  4G04 A;  1HK1 A;  3UIV A;  4L9Q A;  1BJ5 A;  3SQJ A;  1N5U A;  4L9K A;  4LUF A;  3JRY A;  4OR0 A;  3V09 A;  2XVW A;  5IJ5 A;  3LU8 A;  5ID9 A;  5FUO A;  4LB2 A;  4HGK A;  4K2C A;  4JK4 A;  2BXN A;  3JQZ A;  3TDL A;  4G03 A;  1GNI A;  1HK4 A;  1MA9 A;  4K71 A; 
#chains in the Genus database with same CATH topology
 4TQ0 A;  5IIU A;  5GIP A;  2BXH A;  1JNB A;  3GA9 L;  3V08 A;  4Z69 A;  3NVM A;  4ZBK A;  2EFE A;  2BXF A;  1UOR A;  2NQO A;  4ZUX V;  2DYO A;  3V03 A;  4LA0 A;  2V36 A;  4N3Z A;  5GHK A;  3FWB C;  3A75 A;  4HGM B;  3VQI A;  1J78 A;  1E7F A;  2BXP A;  3LU7 A;  4OTU A;  2BXL A;  2CKX A;  2LXT A;  2BX8 A;  5DBY A;  2DYM A;  2EFD A;  4IW1 A;  2XVQ A;  1MIW A;  4OT2 A;  5ID7 A;  2K0N A;  4F5S A;  4BKE A;  1SB0 A;  1BM0 A;  4NAW B;  4WA6 B;  2BXB A;  1E7G A;  4DHX B;  4F5T A;  2XVU A;  1H5W A;  1GNJ A;  2AGH B;  4N0F D;  5DQF A;  4F5V A;  1TF0 A;  4M70 B;  3ECP A;  4I9O A;  2BXK A;  1TXU A;  3PLA A;  4C31 B;  2I30 A;  4LUH A;  1HK3 A;  2Z8K A;  4FJC B;  4D7X A;  1AO6 A;  4FK5 B;  3CX9 A;  3KIK A;  2XMO A;  3GQU A;  4F5U A;  4MBE C;  2BXA A;  2ROH A;  2Z8J A;  1KW2 A;  5B5T A;  2QM6 A;  2BXG A;  2BXO A;  4ZBQ A;  3NMU A;  4GDX A;  1H9Z A;  3A73 A;  4N0U D;  4J2V A;  3WHR A;  3M99 C;  2LQH A;  2VDB A;  4PO0 A;  1VFI A;  4FIP B;  3B9L A;  2YDF A;  2XW0 A;  3ICX A;  3H3A A;  1KXP D;  1E7H A;  2BXM A;  2VUE A;  5GIO A;  3FNM A;  1HK2 A;  2OZB B;  3MHS B;  2E0X A;  2E0Y A;  1HA2 A;  1VZS A;  2GUT A;  3WHS A;  2JUH A;  1J7E A;  1E7I A;  1FOU A;  4E99 A;  2QHB A;  2BXI A;  3BPJ A;  3KJL A;  4W4U B;  4ZBR A;  2VUF A;  4L8U A;  4LB9 A;  3NVI A;  2KWF A;  2BXQ A;  1BKE A;  4BY9 C;  5IIX A;  1KDX A;  4IW2 A;  2OT3 A;  3SIV B;  5IJF A;  1LNS A;  2BXE A;  3FWC C;  5IJE A;  2BXC A;  1MUH A;  2DBU A;  3H37 A;  3SIU B;  3WHQ A;  1MUS A;  1E7A A;  5GIN A;  4EMX A;  1NT2 B;  2I2Z A;  1HK5 A;  3LU6 A;  5IIH A;  1E7E A;  5IFO A;  2XSI A;  5D7G A;  3B9M A;  2XVV A;  2DBX A;  1IJG A;  2BXD A;  4S1Y A;  5HOZ A;  2KBZ A;  2NNW A;  5BPK A;  1E78 A;  3W1S A;  1LOT A;  1E7C A;  3GQX A;  4DM0 A;  1O9X A;  1E7B A;  2XW1 A;  4GDK B;  4G04 A;  1HK1 A;  4TQ1 A;  2LOQ A;  4ZC6 A;  4GG2 A;  3UIV A;  4L9Q A;  4OTT A;  1BJ5 A;  3SQJ A;  2DBW A;  4Z9O A;  1N5U A;  4L9K A;  2EFH A;  3JRY A;  4LUF A;  2QMC A;  4OR0 A;  3V09 A;  1MIY A;  2DG5 A;  4G01 A;  2XVW A;  3G9K D;  5IJ5 A;  3LU8 A;  3MHH B;  5ID9 A;  5FUO A;  1MIV A;  4LB2 A;  2LQI A;  4HGK A;  4K2C A;  4JK4 A;  2BXN A;  2Z8I A;  2AJE A;  2LXS A;  3JQZ A;  3TDL A;  3NVK A;  4G03 A;  2EFC A;  1GNI A;  1HK4 A;  1MA9 A;  4ZCG A;  1MM8 A;  4GDL B;  4K71 A; 
#chains in the Genus database with same CATH homology
 4TQ0 A;  5IIU A;  5GIP A;  2BXH A;  1JNB A;  3GA9 L;  3V08 A;  4Z69 A;  3NVM A;  4ZBK A;  2EFE A;  2BXF A;  1UOR A;  2NQO A;  4ZUX V;  2DYO A;  3V03 A;  4LA0 A;  2V36 A;  4N3Z A;  5GHK A;  3FWB C;  3A75 A;  4HGM B;  3VQI A;  1J78 A;  1E7F A;  2BXP A;  3LU7 A;  4OTU A;  2BXL A;  2CKX A;  5DBY A;  2BX8 A;  2DYM A;  2EFD A;  4IW1 A;  2XVQ A;  1MIW A;  4OT2 A;  5ID7 A;  4F5S A;  4BKE A;  4NAW B;  1BM0 A;  4WA6 B;  2BXB A;  1E7G A;  4DHX B;  4F5T A;  2XVU A;  1H5W A;  1GNJ A;  4N0F D;  5DQF A;  4F5V A;  1TF0 A;  4M70 B;  2BXK A;  1TXU A;  3PLA A;  4C31 B;  2I30 A;  4LUH A;  1HK3 A;  2Z8K A;  4FJC B;  1AO6 A;  4FK5 B;  3CX9 A;  3KIK A;  2XMO A;  3GQU A;  4F5U A;  4MBE C;  2BXA A;  2ROH A;  2Z8J A;  1KW2 A;  5B5T A;  2QM6 A;  2BXG A;  2BXO A;  4ZBQ A;  3NMU A;  4GDX A;  1H9Z A;  3A73 A;  4N0U D;  4J2V A;  3WHR A;  3M99 C;  2VDB A;  4PO0 A;  1VFI A;  4FIP B;  3B9L A;  2YDF A;  2XW0 A;  3ICX A;  3H3A A;  1KXP D;  1E7H A;  2BXM A;  2VUE A;  5GIO A;  3FNM A;  1HK2 A;  2OZB B;  3MHS B;  2E0X A;  2E0Y A;  1HA2 A;  1VZS A;  3WHS A;  2JUH A;  1J7E A;  1E7I A;  1FOU A;  4E99 A;  2QHB A;  2BXI A;  3KJL A;  4W4U B;  4ZBR A;  2VUF A;  4L8U A;  4LB9 A;  3NVI A;  2BXQ A;  1BKE A;  4BY9 C;  5IIX A;  4IW2 A;  2OT3 A;  3SIV B;  5IJF A;  1LNS A;  2BXE A;  3FWC C;  5IJE A;  2BXC A;  3SIU B;  2DBU A;  3H37 A;  3WHQ A;  1E7A A;  5GIN A;  4EMX A;  1NT2 B;  2I2Z A;  1HK5 A;  3LU6 A;  5IIH A;  1E7E A;  5IFO A;  2XSI A;  5D7G A;  3B9M A;  2XVV A;  2DBX A;  1IJG A;  2BXD A;  4S1Y A;  5HOZ A;  2KBZ A;  2NNW A;  5BPK A;  1E78 A;  3W1S A;  1LOT A;  1E7C A;  3GQX A;  1O9X A;  1E7B A;  2XW1 A;  4GDK B;  4G04 A;  1HK1 A;  4TQ1 A;  2LOQ A;  4ZC6 A;  4GG2 A;  3UIV A;  4L9Q A;  4OTT A;  1BJ5 A;  3SQJ A;  2DBW A;  4Z9O A;  1N5U A;  4L9K A;  2EFH A;  3JRY A;  4LUF A;  2QMC A;  4OR0 A;  3V09 A;  1MIY A;  2DG5 A;  4G01 A;  2XVW A;  3G9K D;  5IJ5 A;  3LU8 A;  3MHH B;  5ID9 A;  5FUO A;  1MIV A;  4LB2 A;  4HGK A;  4K2C A;  4JK4 A;  2BXN A;  2Z8I A;  2AJE A;  3JQZ A;  3TDL A;  3NVK A;  4G03 A;  2EFC A;  1GNI A;  1HK4 A;  1MA9 A;  4ZCG A;  4GDL B;  4K71 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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