2BXH | Genus

Total Genus 206

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	206
sequence length	557
structure length	557
Chain Sequence	SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transport protein
source organism	Homo sapiens
publication title	Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	206
structure length	557
sequence length	557
chains with identical sequence	B
ec nomenclature
pdb deposition date	2005-07-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxhA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxhA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxhA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxhA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxhA05
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxhA06

4F5UA 1HK5A 4JK4A 4L9KA 1GNJA 1J7EA 3CX9A 4LB9A 4OT2A 3TDLA 4LB2A 1E7GA 5HOZA 2BXNA 1UORA 5IJFA 1N5UA 3B9MA 2I30A 2BXCA 4ZBRA 2I2ZA 2BX8A 4HGKA 5DBYA 4J2VA 1HK3A 3LU7A 5IIHA 1TF0A 1BKEA 4N0FD 4F5TA 2BXIA 5IFOA 2BXEA 1E7HA 1HK1A 4LUFA 2XW1A 4OR0A 2BXFA 2XVVA 1HK4A 1HK2A 1O9XA 5ID9A 2BXLA 5IJ5A 2BXKA 4LUHA 4F5SA 5DQFA 1HA2A 2XVQA 5GHKA 4ZBQA 1BJ5A 4G03A 2BXBA 1E7IA 3A73A 4N0UD 1BM0A 2BXPA 1MA9A 2BXHA 2XVUA 5FUOA 2YDFA 2XVWA 4E99A 1H9ZA 3V09A 4PO0A 2VDBA 4IW2A 1J78A 4IW1A 1GNIA 2BXQA 3SQJA 4HGMB 2BXDA 1E7CA 3JQZA 4S1YA 4LA0A 3JRYA 3LU8A 3UIVA 2BXGA 5IJEA 4K71A 2VUEA 4L8UA 1E78A 3B9LA 5IIXA 2BXOA 2VUFA 1KXPD 5IIUA 1E7FA 4EMXA 1E7EA 2XW0A 2BXAA 1LOTA 1E7BA 4K2CA 4Z69A 2XSIA 4L9QA 3V08A 3V03A 1E7AA 4F5VA 1KW2A 2BXMA 4G04A 1AO6A 5ID7A 3LU6A 4BKEA
chains in the Genus database with same CATH superfamily

4F5UA 2EFEA 1HK5A 3SIUB 4JK4A 5D7GA 4L9KA 3ICXA 1GNJA 1J7EA 3A75A 3CX9A 4LB9A 2LQIA 4OT2A 3TDLA 2DBWA 2LXTA 2V36A 4LB2A 1E7GA 5HOZA 2BXNA 1UORA 5B5TA 1MM8A 3NMUA 4C31B 2E0YA 2EFHA 3W1SA 3MHHB 4I9OA 4MBEC 5IJFA 1KDXA 2DYOA 2GUTA 1N5UA 4WA6B 3B9MA 2I30A 3GQUA 2BXCA 1TXUA 4ZBRA 2I2ZA 2BX8A 3KJLA 4HGKA 5DBYA 2OZBB 4J2VA 2AGHB 1HK3A 3LU7A 5IIHA 1TF0A 1BKEA 2ROHA 4N0FD 4OTUA 4F5TA 2BXIA 5IFOA 4DHXB 2EFDA 2BXEA 1E7HA 1JNBA 1HK1A 2XW1A 4LUFA 2BXFA 4OR0A 2XVVA 4ZUXV 1HK4A 1HK2A 1O9XA 5ID9A 1IJGA 2BXLA 3SIVB 5IJ5A 2BXKA 4LUHA 4F5SA 5DQFA 1HA2A 1MUSA 4GDXA 2XVQA 2KBZA 5GHKA 2LQHA 4Z9OA 2QMCA 4ZBQA 1BJ5A 2JUHA 3M99C 4DM0A 4G03A 2BXBA 4G01A 1E7IA 2QM6A 3A73A 3KIKA 4W4UB 4N0UD 1MIWA 1BM0A 4ZCGA 2DG5A 2BXPA 2CKXA 3G9KD 1MA9A 4FJCB 2Z8JA 4D7XA 2BXHA 2XVUA 5FUOA 2YDFA 2XVWA 2Z8KA 4N3ZA 4E99A 5GIPA 2LXSA 1H9ZA 3FWCC 2K0NA 4GDLB 2DBUA 3FWBC 3MHSB 2VDBA 4PO0A 3V09A 4IW2A 3PLAA 1MIYA 1J78A 1MIVA 4IW1A 2AJEA 1GNIA 2BXQA 3SQJA 3H37A 4TQ0A 2OT3A 4HGMB 1LNSA 3FNMA 2BXDA 1E7CA 3JQZA 4FK5B 4LA0A 4S1YA 4BY9C 4OTTA 3JRYA 5GINA 3NVIA 3LU8A 4GG2A 3UIVA 2E0XA 2BXGA 3WHQA 2XMOA 3BPJA 4TQ1A 5IJEA 4K71A 2VUEA 4L8UA 1E78A 3B9LA 2QHBA 5IIXA 4GDKB 3WHRA 2Z8IA 3WHSA 2BXOA 4M70B 4NAWB 3VQIA 5GIOA 2NNWA 2NQOA 1VZSA 1KXPD 2VUFA 2LOQA 5IIUA 1E7FA 3NVKA 1SB0A 4EMXA 1E7EA 2XW0A 2BXAA 1LOTA 3H3AA 1E7BA 4K2CA 2EFCA 4Z69A 3GA9L 2DYMA 2XSIA 2DBXA 3ECPA 5BPKA 1VFIA 1MUHA 1FOUA 4FIPB 3GQXA 4L9QA 3V08A 2KWFA 3V03A 1E7AA 3NVMA 4F5VA 1KW2A 4ZC6A 1NT2B 2BXMA 4G04A 1AO6A 1H5WA 5ID7A 3LU6A 4BKEA 4ZBKA
chains in the Genus database with same CATH topology

4F5UA 2EFEA 1HK5A 3SIUB 4JK4A 5D7GA 4L9KA 3ICXA 1GNJA 1J7EA 3A75A 3CX9A 4LB9A 4OT2A 5B5TA 3TDLA 2DBWA 2V36A 4LB2A 1E7GA 5HOZA 2BXNA 1UORA 3NMUA 4C31B 2E0YA 2EFHA 3W1SA 3MHHB 4MBEC 5IJFA 2DYOA 1N5UA 4WA6B 3B9MA 2I30A 3GQUA 2BXCA 1TXUA 4ZBRA 2I2ZA 2BX8A 3KJLA 4HGKA 5DBYA 2OZBB 4J2VA 1HK3A 3LU7A 5IIHA 1TF0A 1BKEA 2ROHA 4N0FD 4OTUA 4F5TA 2BXIA 5IFOA 4DHXB 2EFDA 2BXEA 1E7HA 1JNBA 1HK1A 2XW1A 4LUFA 2BXFA 4OR0A 2XVVA 4ZUXV 1HK4A 1HK2A 1O9XA 5ID9A 1IJGA 2BXLA 3SIVB 5IJ5A 2BXKA 4LUHA 4F5SA 5DQFA 1HA2A 4GDXA 2XVQA 2KBZA 5GHKA 4Z9OA 2QMCA 4ZBQA 1BJ5A 2JUHA 3M99C 4G03A 2BXBA 4G01A 1E7IA 2QM6A 3A73A 3KIKA 4W4UB 4N0UD 1MIWA 1BM0A 4ZCGA 2DG5A 2BXPA 2CKXA 3G9KD 1MA9A 4FJCB 2Z8JA 2BXHA 2XVUA 5FUOA 2YDFA 2XVWA 2Z8KA 4N3ZA 4E99A 5GIPA 1H9ZA 3FWCC 4GDLB 2DBUA 3FWBC 3MHSB 2VDBA 4PO0A 3V09A 4IW2A 3PLAA 1MIYA 1J78A 1MIVA 4IW1A 2AJEA 1GNIA 2BXQA 3SQJA 3H37A 4TQ0A 2OT3A 4HGMB 1LNSA 3FNMA 2BXDA 1E7CA 3JQZA 4FK5B 4LA0A 4S1YA 4BY9C 4OTTA 3JRYA 5GINA 3NVIA 3LU8A 4GG2A 3UIVA 2E0XA 2BXGA 3WHQA 2XMOA 4TQ1A 5IJEA 4K71A 2VUEA 4L8UA 1E78A 3B9LA 2QHBA 5IIXA 4GDKB 3WHRA 2Z8IA 3WHSA 2BXOA 4M70B 4NAWB 3VQIA 5GIOA 2NNWA 2NQOA 1VZSA 1KXPD 2VUFA 2LOQA 5IIUA 1E7FA 3NVKA 4EMXA 1E7EA 2XW0A 2BXAA 1LOTA 3H3AA 1E7BA 4K2CA 2EFCA 4Z69A 3GA9L 2DYMA 2XSIA 2DBXA 5BPKA 1VFIA 1FOUA 4FIPB 3GQXA 4L9QA 3V08A 3V03A 1E7AA 3NVMA 4F5VA 1KW2A 4ZC6A 1NT2B 2BXMA 4G04A 1AO6A 1H5WA 5ID7A 3LU6A 4BKEA 4ZBKA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4F5U A;  1HK5 A;  4JK4 A;  4L9K A;  1GNJ A;  1J7E A;  3CX9 A;  4LB9 A;  4OT2 A;  3TDL A;  4LB2 A;  1E7G A;  5HOZ A;  2BXN A;  1UOR A;  5IJF A;  1N5U A;  3B9M A;  2I30 A;  2BXC A;  4ZBR A;  2I2Z A;  2BX8 A;  4HGK A;  5DBY A;  4J2V A;  1HK3 A;  3LU7 A;  5IIH A;  1TF0 A;  1BKE A;  4N0F D;  4F5T A;  2BXI A;  5IFO A;  2BXE A;  1E7H A;  1HK1 A;  4LUF A;  2XW1 A;  4OR0 A;  2BXF A;  2XVV A;  1HK4 A;  1HK2 A;  1O9X A;  5ID9 A;  2BXL A;  5IJ5 A;  2BXK A;  4LUH A;  4F5S A;  5DQF A;  1HA2 A;  2XVQ A;  5GHK A;  4ZBQ A;  1BJ5 A;  4G03 A;  2BXB A;  1E7I A;  3A73 A;  4N0U D;  1BM0 A;  2BXP A;  1MA9 A;  2BXH A;  2XVU A;  5FUO A;  2YDF A;  2XVW A;  4E99 A;  1H9Z A;  3V09 A;  4PO0 A;  2VDB A;  4IW2 A;  1J78 A;  4IW1 A;  1GNI A;  2BXQ A;  3SQJ A;  4HGM B;  2BXD A;  1E7C A;  3JQZ A;  4S1Y A;  4LA0 A;  3JRY A;  3LU8 A;  3UIV A;  2BXG A;  5IJE A;  4K71 A;  2VUE A;  4L8U A;  1E78 A;  3B9L A;  5IIX A;  2BXO A;  2VUF A;  1KXP D;  5IIU A;  1E7F A;  4EMX A;  1E7E A;  2XW0 A;  2BXA A;  1LOT A;  1E7B A;  4K2C A;  4Z69 A;  2XSI A;  4L9Q A;  3V08 A;  3V03 A;  1E7A A;  4F5V A;  1KW2 A;  2BXM A;  4G04 A;  1AO6 A;  5ID7 A;  3LU6 A;  4BKE A; 
#chains in the Genus database with same CATH topology
 4F5U A;  2EFE A;  1HK5 A;  3SIU B;  4JK4 A;  5D7G A;  4L9K A;  3ICX A;  1GNJ A;  1J7E A;  3A75 A;  3CX9 A;  4LB9 A;  2LQI A;  4OT2 A;  3TDL A;  2DBW A;  2LXT A;  2V36 A;  4LB2 A;  1E7G A;  5HOZ A;  2BXN A;  1UOR A;  5B5T A;  1MM8 A;  3NMU A;  4C31 B;  2E0Y A;  2EFH A;  3W1S A;  3MHH B;  4I9O A;  4MBE C;  5IJF A;  1KDX A;  2DYO A;  2GUT A;  1N5U A;  4WA6 B;  3B9M A;  2I30 A;  3GQU A;  2BXC A;  1TXU A;  4ZBR A;  2I2Z A;  2BX8 A;  3KJL A;  4HGK A;  5DBY A;  2OZB B;  4J2V A;  2AGH B;  1HK3 A;  3LU7 A;  5IIH A;  1TF0 A;  1BKE A;  2ROH A;  4N0F D;  4OTU A;  4F5T A;  2BXI A;  5IFO A;  4DHX B;  2EFD A;  2BXE A;  1E7H A;  1JNB A;  1HK1 A;  2XW1 A;  4LUF A;  2BXF A;  4OR0 A;  2XVV A;  4ZUX V;  1HK4 A;  1HK2 A;  1O9X A;  5ID9 A;  1IJG A;  2BXL A;  3SIV B;  5IJ5 A;  2BXK A;  4LUH A;  4F5S A;  5DQF A;  1HA2 A;  1MUS A;  4GDX A;  2XVQ A;  2KBZ A;  5GHK A;  2LQH A;  4Z9O A;  2QMC A;  4ZBQ A;  1BJ5 A;  2JUH A;  3M99 C;  4DM0 A;  4G03 A;  2BXB A;  4G01 A;  1E7I A;  2QM6 A;  3A73 A;  3KIK A;  4W4U B;  4N0U D;  1MIW A;  1BM0 A;  4ZCG A;  2DG5 A;  2BXP A;  2CKX A;  3G9K D;  1MA9 A;  4FJC B;  2Z8J A;  4D7X A;  2BXH A;  2XVU A;  5FUO A;  2YDF A;  2XVW A;  2Z8K A;  4N3Z A;  4E99 A;  5GIP A;  2LXS A;  1H9Z A;  3FWC C;  2K0N A;  4GDL B;  2DBU A;  3FWB C;  3MHS B;  2VDB A;  4PO0 A;  3V09 A;  4IW2 A;  3PLA A;  1MIY A;  1J78 A;  1MIV A;  4IW1 A;  2AJE A;  1GNI A;  2BXQ A;  3SQJ A;  3H37 A;  4TQ0 A;  2OT3 A;  4HGM B;  1LNS A;  3FNM A;  2BXD A;  1E7C A;  3JQZ A;  4FK5 B;  4LA0 A;  4S1Y A;  4BY9 C;  4OTT A;  3JRY A;  5GIN A;  3NVI A;  3LU8 A;  4GG2 A;  3UIV A;  2E0X A;  2BXG A;  3WHQ A;  2XMO A;  3BPJ A;  4TQ1 A;  5IJE A;  4K71 A;  2VUE A;  4L8U A;  1E78 A;  3B9L A;  2QHB A;  5IIX A;  4GDK B;  3WHR A;  2Z8I A;  3WHS A;  2BXO A;  4M70 B;  4NAW B;  3VQI A;  5GIO A;  2NNW A;  2NQO A;  1VZS A;  1KXP D;  2VUF A;  2LOQ A;  5IIU A;  1E7F A;  3NVK A;  1SB0 A;  4EMX A;  1E7E A;  2XW0 A;  2BXA A;  1LOT A;  3H3A A;  1E7B A;  4K2C A;  2EFC A;  4Z69 A;  3GA9 L;  2DYM A;  2XSI A;  2DBX A;  3ECP A;  5BPK A;  1VFI A;  1MUH A;  1FOU A;  4FIP B;  3GQX A;  4L9Q A;  3V08 A;  2KWF A;  3V03 A;  1E7A A;  3NVM A;  4F5V A;  1KW2 A;  4ZC6 A;  1NT2 B;  2BXM A;  4G04 A;  1AO6 A;  1H5W A;  5ID7 A;  3LU6 A;  4BKE A;  4ZBK A; 
#chains in the Genus database with same CATH homology
 4F5U A;  2EFE A;  1HK5 A;  3SIU B;  4JK4 A;  5D7G A;  4L9K A;  3ICX A;  1GNJ A;  1J7E A;  3A75 A;  3CX9 A;  4LB9 A;  4OT2 A;  5B5T A;  3TDL A;  2DBW A;  2V36 A;  4LB2 A;  1E7G A;  5HOZ A;  2BXN A;  1UOR A;  3NMU A;  4C31 B;  2E0Y A;  2EFH A;  3W1S A;  3MHH B;  4MBE C;  5IJF A;  2DYO A;  1N5U A;  4WA6 B;  3B9M A;  2I30 A;  3GQU A;  2BXC A;  1TXU A;  4ZBR A;  2I2Z A;  2BX8 A;  3KJL A;  4HGK A;  5DBY A;  2OZB B;  4J2V A;  1HK3 A;  3LU7 A;  5IIH A;  1TF0 A;  1BKE A;  2ROH A;  4N0F D;  4OTU A;  4F5T A;  2BXI A;  5IFO A;  4DHX B;  2EFD A;  2BXE A;  1E7H A;  1JNB A;  1HK1 A;  2XW1 A;  4LUF A;  2BXF A;  4OR0 A;  2XVV A;  4ZUX V;  1HK4 A;  1HK2 A;  1O9X A;  5ID9 A;  1IJG A;  2BXL A;  3SIV B;  5IJ5 A;  2BXK A;  4LUH A;  4F5S A;  5DQF A;  1HA2 A;  4GDX A;  2XVQ A;  2KBZ A;  5GHK A;  4Z9O A;  2QMC A;  4ZBQ A;  1BJ5 A;  2JUH A;  3M99 C;  4G03 A;  2BXB A;  4G01 A;  1E7I A;  2QM6 A;  3A73 A;  3KIK A;  4W4U B;  4N0U D;  1MIW A;  1BM0 A;  4ZCG A;  2DG5 A;  2BXP A;  2CKX A;  3G9K D;  1MA9 A;  4FJC B;  2Z8J A;  2BXH A;  2XVU A;  5FUO A;  2YDF A;  2XVW A;  2Z8K A;  4N3Z A;  4E99 A;  5GIP A;  1H9Z A;  3FWC C;  4GDL B;  2DBU A;  3FWB C;  3MHS B;  2VDB A;  4PO0 A;  3V09 A;  4IW2 A;  3PLA A;  1MIY A;  1J78 A;  1MIV A;  4IW1 A;  2AJE A;  1GNI A;  2BXQ A;  3SQJ A;  3H37 A;  4TQ0 A;  2OT3 A;  4HGM B;  1LNS A;  3FNM A;  2BXD A;  1E7C A;  3JQZ A;  4FK5 B;  4LA0 A;  4S1Y A;  4BY9 C;  4OTT A;  3JRY A;  5GIN A;  3NVI A;  3LU8 A;  4GG2 A;  3UIV A;  2E0X A;  2BXG A;  3WHQ A;  2XMO A;  4TQ1 A;  5IJE A;  4K71 A;  2VUE A;  4L8U A;  1E78 A;  3B9L A;  2QHB A;  5IIX A;  4GDK B;  3WHR A;  2Z8I A;  3WHS A;  2BXO A;  4M70 B;  4NAW B;  3VQI A;  5GIO A;  2NNW A;  2NQO A;  1VZS A;  1KXP D;  2VUF A;  2LOQ A;  5IIU A;  1E7F A;  3NVK A;  4EMX A;  1E7E A;  2XW0 A;  2BXA A;  1LOT A;  3H3A A;  1E7B A;  4K2C A;  2EFC A;  4Z69 A;  3GA9 L;  2DYM A;  2XSI A;  2DBX A;  5BPK A;  1VFI A;  1FOU A;  4FIP B;  3GQX A;  4L9Q A;  3V08 A;  3V03 A;  1E7A A;  3NVM A;  4F5V A;  1KW2 A;  4ZC6 A;  1NT2 B;  2BXM A;  4G04 A;  1AO6 A;  1H5W A;  5ID7 A;  3LU6 A;  4BKE A;  4ZBK A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2BXHA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations