2BXKA

Human serum albumin complexed with myristate, azapropazone and indomethacin
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKEEQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 226
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA05
3TDLA 2I30A 4LB2A 2BXIA 2BXFA 2I2ZA 2BXNA 2BXHA 2BXMA 4ZBRA 2BXLA 5IJFA 2BXEA 2XVVA 1LOTA 2BXKA 1E7BA 5IFOA 3CX9A 1E7FA 3A73A 2BXDA 5IIXA 4HGMB 2XW0A 1N5UA 1UORA 1J7EA 4F5UA 3LU8A 1O9XA 4K71A 1HK5A 5IJ5A 2VDBA 4OT2A 1E7AA 2BXPA 4L9KA 1E7IA 1E7GA 4IW1A 4LUHA 3B9LA 1J78A 4G04A 4N0UD 4F5SA 2BXQA 1E7HA 2YDFA 3JQZA 4L9QA 5ID9A 1BJ5A 2BXOA 4LB9A 1BKEA 4K2CA 4L8UA 4EMXA 4BKEA 4PO0A 3V03A 3LU6A 2XVWA 5HOZA 3SQJA 1E78A 4Z69A 3UIVA 4E99A 4J2VA 1MA9A 2XSIA 3LU7A 4LA0A 1HA2A 4F5TA 2VUEA 3JRYA 4JK4A 4OR0A 2BXCA 2BX8A 4ZBQA 3V09A 4N0FD 1E7CA 1KW2A 4HGKA 4IW2A 4LUFA 5IIHA 1GNJA 1H9ZA 3V08A 1KXPD 1HK2A 2XVUA 1BM0A 1HK3A 5IIUA 2BXBA 5ID7A 1TF0A 2XW1A 1GNIA 1AO6A 1HK1A 5IJEA 2XVQA 3B9MA 2BXAA 1E7EA 2VUFA 1HK4A 4F5VA 5FUOA 5DQFA 2BXGA 5DBYA 4G03A 5GHKA 4S1YA
chains in the Genus database with same CATH superfamily
3TDLA 2I30A 4LB2A 2BXIA 2BXFA 2I2ZA 3FWCC 2BXNA 2BXHA 2AGHB 2BXMA 4ZBRA 2BXLA 5IJFA 2BXEA 2XVVA 2OZBB 4DHXB 2QHBA 3PLAA 1LOTA 3NVMA 1VZSA 2BXKA 4DM0A 4NAWB 3FNMA 1E7BA 3M99C 5IFOA 2E0XA 2E0YA 3CX9A 5GIOA 1TXUA 1E7FA 1MIVA 1MIWA 3A73A 5GINA 2DBXA 2BXDA 3GQXA 2Z8IA 5IIXA 4ZUXV 4HGMB 2XW0A 1N5UA 1UORA 1J7EA 4F5UA 1O9XA 3LU8A 4K71A 4OTTA 4GDXA 1HK5A 2EFHA 2VDBA 5IJ5A 3W1SA 4OT2A 1E7AA 2LOQA 2BXPA 2OT3A 4L9KA 4BY9C 1E7IA 3GA9L 1SB0A 3WHSA 1E7GA 4IW1A 1IJGA 3B9LA 4LUHA 4TQ1A 3FWBC 1J78A 4Z9OA 4D7XA 4ZCGA 4G04A 4N0UD 3WHQA 4F5SA 4FIPB 1VFIA 2BXQA 1MIYA 4GG2A 1E7HA 2NNWA 2YDFA 3JQZA 4L9QA 5ID9A 1BJ5A 2BXOA 3H37A 4LB9A 4WA6B 1BKEA 4K2CA 4L8UA 4EMXA 2DYOA 4BKEA 3ECPA 4PO0A 3V03A 3SIVB 3LU6A 3NMUA 3GQUA 1FOUA 2XVWA 3KIKA 5HOZA 4TQ0A 3SQJA 1E78A 1KDXA 4Z69A 4S1YA 3UIVA 4E99A 3NVKA 1H5WA 2JUHA 1MUHA 4J2VA 1MA9A 2XSIA 3LU7A 3H3AA 4LA0A 1HA2A 2XMOA 2VUEA 3JRYA 3WHRA 4MBEC 4JK4A 4F5TA 1MUSA 4OR0A 2BXCA 2BX8A 2LQIA 4ZBKA 5D7GA 3MHHB 2DBWA 4ZBQA 3V09A 4N0FD 4GDLB 4I9OA 3SIUB 2LXSA 1E7CA 3NVIA 2DG5A 1KW2A 3KJLA 4HGKA 4IW2A 4LUFA 5IIHA 1GNJA 1H9ZA 5BPKA 2DBUA 3V08A 1KXPD 1HK2A 1NT2B 2NQOA 3MHSB 2XVUA 1BM0A 1HK3A 2ROHA 2BXBA 5IIUA 2EFDA 2GUTA 2LQHA 2V36A 4W4UB 2Z8KA 5B5TA 4FJCB 2KWFA 5ID7A 5GIPA 1MM8A 4C31B 1TF0A 2K0NA 2XW1A 1GNIA 2DYMA 1AO6A 2EFEA 1HK1A 2EFCA 4FK5B 5IJEA 2XVQA 3B9MA 4G01A 2QM6A 2BXAA 4M70B 4ZC6A 2LXTA 1E7EA 3G9KD 2VUFA 3ICXA 4GDKB 3VQIA 4N3ZA 3A75A 2AJEA 4OTUA 1HK4A 2KBZA 4F5VA 5FUOA 5DQFA 1LNSA 2BXGA 3BPJA 5DBYA 4G03A 5GHKA 1JNBA 2CKXA 2QMCA 2Z8JA
chains in the Genus database with same CATH topology
3TDLA 2I30A 4LB2A 2BXIA 2BXFA 2I2ZA 3FWCC 2BXNA 2BXHA 2BXMA 4ZBRA 2BXLA 5IJFA 2BXEA 2XVVA 2OZBB 4DHXB 2QHBA 3PLAA 1LOTA 3NVMA 1VZSA 2BXKA 4NAWB 3FNMA 1E7BA 3M99C 5IFOA 2E0XA 2E0YA 3CX9A 5GIOA 1TXUA 1E7FA 1MIVA 1MIWA 3A73A 5GINA 2DBXA 2BXDA 3GQXA 2Z8IA 5IIXA 4ZUXV 4HGMB 2XW0A 1N5UA 1UORA 1J7EA 4F5UA 1O9XA 3LU8A 4K71A 4OTTA 4GDXA 1HK5A 2EFHA 2VDBA 5IJ5A 3W1SA 4OT2A 1E7AA 2LOQA 2BXPA 2OT3A 4L9KA 4BY9C 1E7IA 3GA9L 3WHSA 1E7GA 4IW1A 1IJGA 3B9LA 4LUHA 4TQ1A 3FWBC 1J78A 4Z9OA 4ZCGA 4G04A 4N0UD 3WHQA 4F5SA 4FIPB 1VFIA 2BXQA 1MIYA 4GG2A 1E7HA 2NNWA 2YDFA 3JQZA 4L9QA 5ID9A 1BJ5A 2BXOA 3H37A 4LB9A 4WA6B 1BKEA 4K2CA 4L8UA 4EMXA 2DYOA 4BKEA 3SIVB 4PO0A 3V03A 3LU6A 3NMUA 3GQUA 1FOUA 2XVWA 3KIKA 5HOZA 4TQ0A 3SQJA 1E78A 4Z69A 4S1YA 3UIVA 4E99A 3NVKA 1H5WA 2JUHA 4J2VA 1MA9A 2XSIA 3LU7A 3H3AA 4LA0A 1HA2A 2XMOA 2VUEA 3JRYA 3WHRA 4MBEC 4JK4A 4F5TA 4OR0A 2BXCA 2BX8A 4ZBKA 5D7GA 3MHHB 2DBWA 4ZBQA 3V09A 4N0FD 4GDLB 3SIUB 1E7CA 3NVIA 2DG5A 1KW2A 3KJLA 4HGKA 4IW2A 4LUFA 5IIHA 1GNJA 1H9ZA 5BPKA 2DBUA 3V08A 1KXPD 1HK2A 1NT2B 2NQOA 3MHSB 2XVUA 1BM0A 1HK3A 2ROHA 2BXBA 5IIUA 2EFDA 5B5TA 2V36A 4W4UB 2Z8KA 4FJCB 5ID7A 5GIPA 4C31B 1TF0A 2XW1A 1GNIA 2DYMA 1AO6A 2EFEA 1HK1A 2EFCA 4FK5B 5IJEA 2XVQA 3B9MA 4G01A 2QM6A 2BXAA 4M70B 4ZC6A 1E7EA 3G9KD 2VUFA 3ICXA 4GDKB 3VQIA 4N3ZA 3A75A 2AJEA 4OTUA 1HK4A 2KBZA 4F5VA 5FUOA 5DQFA 1LNSA 2BXGA 5DBYA 4G03A 5GHKA 1JNBA 2CKXA 2QMCA 2Z8JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TDL A;  2I30 A;  4LB2 A;  2BXI A;  2BXF A;  2I2Z A;  2BXN A;  2BXH A;  2BXM A;  4ZBR A;  2BXL A;  5IJF A;  2BXE A;  2XVV A;  1LOT A;  2BXK A;  1E7B A;  5IFO A;  3CX9 A;  1E7F A;  3A73 A;  2BXD A;  5IIX A;  4HGM B;  2XW0 A;  1N5U A;  1UOR A;  1J7E A;  4F5U A;  3LU8 A;  1O9X A;  4K71 A;  1HK5 A;  5IJ5 A;  2VDB A;  4OT2 A;  1E7A A;  2BXP A;  4L9K A;  1E7I A;  1E7G A;  4IW1 A;  4LUH A;  3B9L A;  1J78 A;  4G04 A;  4N0U D;  4F5S A;  2BXQ A;  1E7H A;  2YDF A;  3JQZ A;  4L9Q A;  5ID9 A;  1BJ5 A;  2BXO A;  4LB9 A;  1BKE A;  4K2C A;  4L8U A;  4EMX A;  4BKE A;  4PO0 A;  3V03 A;  3LU6 A;  2XVW A;  5HOZ A;  3SQJ A;  1E78 A;  4Z69 A;  3UIV A;  4E99 A;  4J2V A;  1MA9 A;  2XSI A;  3LU7 A;  4LA0 A;  1HA2 A;  4F5T A;  2VUE A;  3JRY A;  4JK4 A;  4OR0 A;  2BXC A;  2BX8 A;  4ZBQ A;  3V09 A;  4N0F D;  1E7C A;  1KW2 A;  4HGK A;  4IW2 A;  4LUF A;  5IIH A;  1GNJ A;  1H9Z A;  3V08 A;  1KXP D;  1HK2 A;  2XVU A;  1BM0 A;  1HK3 A;  5IIU A;  2BXB A;  5ID7 A;  1TF0 A;  2XW1 A;  1GNI A;  1AO6 A;  1HK1 A;  5IJE A;  2XVQ A;  3B9M A;  2BXA A;  1E7E A;  2VUF A;  1HK4 A;  4F5V A;  5FUO A;  5DQF A;  2BXG A;  5DBY A;  4G03 A;  5GHK A;  4S1Y A; 
#chains in the Genus database with same CATH topology
 3TDL A;  2I30 A;  4LB2 A;  2BXI A;  2BXF A;  2I2Z A;  3FWC C;  2BXN A;  2BXH A;  2AGH B;  2BXM A;  4ZBR A;  2BXL A;  5IJF A;  2BXE A;  2XVV A;  2OZB B;  4DHX B;  2QHB A;  3PLA A;  1LOT A;  3NVM A;  1VZS A;  2BXK A;  4DM0 A;  4NAW B;  3FNM A;  1E7B A;  3M99 C;  5IFO A;  2E0X A;  2E0Y A;  3CX9 A;  5GIO A;  1TXU A;  1E7F A;  1MIV A;  1MIW A;  3A73 A;  5GIN A;  2DBX A;  2BXD A;  3GQX A;  2Z8I A;  5IIX A;  4ZUX V;  4HGM B;  2XW0 A;  1N5U A;  1UOR A;  1J7E A;  4F5U A;  1O9X A;  3LU8 A;  4K71 A;  4OTT A;  4GDX A;  1HK5 A;  2EFH A;  2VDB A;  5IJ5 A;  3W1S A;  4OT2 A;  1E7A A;  2LOQ A;  2BXP A;  2OT3 A;  4L9K A;  4BY9 C;  1E7I A;  3GA9 L;  1SB0 A;  3WHS A;  1E7G A;  4IW1 A;  1IJG A;  3B9L A;  4LUH A;  4TQ1 A;  3FWB C;  1J78 A;  4Z9O A;  4D7X A;  4ZCG A;  4G04 A;  4N0U D;  3WHQ A;  4F5S A;  4FIP B;  1VFI A;  2BXQ A;  1MIY A;  4GG2 A;  1E7H A;  2NNW A;  2YDF A;  3JQZ A;  4L9Q A;  5ID9 A;  1BJ5 A;  2BXO A;  3H37 A;  4LB9 A;  4WA6 B;  1BKE A;  4K2C A;  4L8U A;  4EMX A;  2DYO A;  4BKE A;  3ECP A;  4PO0 A;  3V03 A;  3SIV B;  3LU6 A;  3NMU A;  3GQU A;  1FOU A;  2XVW A;  3KIK A;  5HOZ A;  4TQ0 A;  3SQJ A;  1E78 A;  1KDX A;  4Z69 A;  4S1Y A;  3UIV A;  4E99 A;  3NVK A;  1H5W A;  2JUH A;  1MUH A;  4J2V A;  1MA9 A;  2XSI A;  3LU7 A;  3H3A A;  4LA0 A;  1HA2 A;  2XMO A;  2VUE A;  3JRY A;  3WHR A;  4MBE C;  4JK4 A;  4F5T A;  1MUS A;  4OR0 A;  2BXC A;  2BX8 A;  2LQI A;  4ZBK A;  5D7G A;  3MHH B;  2DBW A;  4ZBQ A;  3V09 A;  4N0F D;  4GDL B;  4I9O A;  3SIU B;  2LXS A;  1E7C A;  3NVI A;  2DG5 A;  1KW2 A;  3KJL A;  4HGK A;  4IW2 A;  4LUF A;  5IIH A;  1GNJ A;  1H9Z A;  5BPK A;  2DBU A;  3V08 A;  1KXP D;  1HK2 A;  1NT2 B;  2NQO A;  3MHS B;  2XVU A;  1BM0 A;  1HK3 A;  2ROH A;  2BXB A;  5IIU A;  2EFD A;  2GUT A;  2LQH A;  2V36 A;  4W4U B;  2Z8K A;  5B5T A;  4FJC B;  2KWF A;  5ID7 A;  5GIP A;  1MM8 A;  4C31 B;  1TF0 A;  2K0N A;  2XW1 A;  1GNI A;  2DYM A;  1AO6 A;  2EFE A;  1HK1 A;  2EFC A;  4FK5 B;  5IJE A;  2XVQ A;  3B9M A;  4G01 A;  2QM6 A;  2BXA A;  4M70 B;  4ZC6 A;  2LXT A;  1E7E A;  3G9K D;  2VUF A;  3ICX A;  4GDK B;  3VQI A;  4N3Z A;  3A75 A;  2AJE A;  4OTU A;  1HK4 A;  2KBZ A;  4F5V A;  5FUO A;  5DQF A;  1LNS A;  2BXG A;  3BPJ A;  5DBY A;  4G03 A;  5GHK A;  1JNB A;  2CKX A;  2QMC A;  2Z8J A; 
#chains in the Genus database with same CATH homology
 3TDL A;  2I30 A;  4LB2 A;  2BXI A;  2BXF A;  2I2Z A;  3FWC C;  2BXN A;  2BXH A;  2BXM A;  4ZBR A;  2BXL A;  5IJF A;  2BXE A;  2XVV A;  2OZB B;  4DHX B;  2QHB A;  3PLA A;  1LOT A;  3NVM A;  1VZS A;  2BXK A;  4NAW B;  3FNM A;  1E7B A;  3M99 C;  5IFO A;  2E0X A;  2E0Y A;  3CX9 A;  5GIO A;  1TXU A;  1E7F A;  1MIV A;  1MIW A;  3A73 A;  5GIN A;  2DBX A;  2BXD A;  3GQX A;  2Z8I A;  5IIX A;  4ZUX V;  4HGM B;  2XW0 A;  1N5U A;  1UOR A;  1J7E A;  4F5U A;  1O9X A;  3LU8 A;  4K71 A;  4OTT A;  4GDX A;  1HK5 A;  2EFH A;  2VDB A;  5IJ5 A;  3W1S A;  4OT2 A;  1E7A A;  2LOQ A;  2BXP A;  2OT3 A;  4L9K A;  4BY9 C;  1E7I A;  3GA9 L;  3WHS A;  1E7G A;  4IW1 A;  1IJG A;  3B9L A;  4LUH A;  4TQ1 A;  3FWB C;  1J78 A;  4Z9O A;  4ZCG A;  4G04 A;  4N0U D;  3WHQ A;  4F5S A;  4FIP B;  1VFI A;  2BXQ A;  1MIY A;  4GG2 A;  1E7H A;  2NNW A;  2YDF A;  3JQZ A;  4L9Q A;  5ID9 A;  1BJ5 A;  2BXO A;  3H37 A;  4LB9 A;  4WA6 B;  1BKE A;  4K2C A;  4L8U A;  4EMX A;  2DYO A;  4BKE A;  3SIV B;  4PO0 A;  3V03 A;  3LU6 A;  3NMU A;  3GQU A;  1FOU A;  2XVW A;  3KIK A;  5HOZ A;  4TQ0 A;  3SQJ A;  1E78 A;  4Z69 A;  4S1Y A;  3UIV A;  4E99 A;  3NVK A;  1H5W A;  2JUH A;  4J2V A;  1MA9 A;  2XSI A;  3LU7 A;  3H3A A;  4LA0 A;  1HA2 A;  2XMO A;  2VUE A;  3JRY A;  3WHR A;  4MBE C;  4JK4 A;  4F5T A;  4OR0 A;  2BXC A;  2BX8 A;  4ZBK A;  5D7G A;  3MHH B;  2DBW A;  4ZBQ A;  3V09 A;  4N0F D;  4GDL B;  3SIU B;  1E7C A;  3NVI A;  2DG5 A;  1KW2 A;  3KJL A;  4HGK A;  4IW2 A;  4LUF A;  5IIH A;  1GNJ A;  1H9Z A;  5BPK A;  2DBU A;  3V08 A;  1KXP D;  1HK2 A;  1NT2 B;  2NQO A;  3MHS B;  2XVU A;  1BM0 A;  1HK3 A;  2ROH A;  2BXB A;  5IIU A;  2EFD A;  5B5T A;  2V36 A;  4W4U B;  2Z8K A;  4FJC B;  5ID7 A;  5GIP A;  4C31 B;  1TF0 A;  2XW1 A;  1GNI A;  2DYM A;  1AO6 A;  2EFE A;  1HK1 A;  2EFC A;  4FK5 B;  5IJE A;  2XVQ A;  3B9M A;  4G01 A;  2QM6 A;  2BXA A;  4M70 B;  4ZC6 A;  1E7E A;  3G9K D;  2VUF A;  3ICX A;  4GDK B;  3VQI A;  4N3Z A;  3A75 A;  2AJE A;  4OTU A;  1HK4 A;  2KBZ A;  4F5V A;  5FUO A;  5DQF A;  1LNS A;  2BXG A;  5DBY A;  4G03 A;  5GHK A;  1JNB A;  2CKX A;  2QMC A;  2Z8J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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