2BXK | Genus

Total Genus 226

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	226
sequence length	582
structure length	582
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKEEQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transport protein
source organism	Homo sapiens
publication title	Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	226
structure length	582
sequence length	582
ec nomenclature
pdb deposition date	2005-07-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxkA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxkA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxkA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxkA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxkA06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxkA05

1HK3A 4L9QA 2BXCA 3LU7A 5IIHA 3UIVA 2XSIA 1E7HA 3A73A 4LA0A 5ID9A 1E7BA 4IW2A 1E7GA 4F5SA 2BX8A 2BXHA 1HA2A 1HK2A 1GNIA 4E99A 2BXOA 4IW1A 1E7IA 1UORA 4G03A 2BXMA 1J78A 4K2CA 4S1YA 3JRYA 5IFOA 2BXEA 2I2ZA 1E7AA 4F5VA 3TDLA 4LUFA 4G04A 2XVVA 1N5UA 5GHKA 1E78A 3LU8A 4EMXA 5ID7A 4F5UA 4BKEA 2BXNA 5IIXA 4PO0A 2BXDA 1GNJA 2BXPA 2BXIA 4L9KA 4N0FD 1BM0A 1O9XA 4ZBQA 4HGKA 4LB9A 3V08A 2BXKA 4L8UA 1HK4A 2XW0A 4K71A 1E7EA 1E7CA 1AO6A 1BJ5A 1HK5A 1KXPD 5HOZA 3SQJA 5IJEA 3V09A 3B9MA 4HGMB 2BXQA 2VUFA 2BXGA 5FUOA 4LUHA 2BXFA 3V03A 1H9ZA 3CX9A 2VDBA 1KW2A 2XW1A 1LOTA 5DBYA 2I30A 1BKEA 2BXLA 5IIUA 4LB2A 2XVWA 2BXBA 1E7FA 2XVQA 4OT2A 2XVUA 4J2VA 2BXAA 4N0UD 4OR0A 1TF0A 4ZBRA 1HK1A 1J7EA 5IJFA 4F5TA 3JQZA 4JK4A 2VUEA 1MA9A 5IJ5A 2YDFA 3LU6A 3B9LA 5DQFA 4Z69A
chains in the Genus database with same CATH superfamily

2AGHB 1HK3A 4L9QA 2BXCA 2OT3A 2V36A 3LU7A 5IIHA 3UIVA 2XSIA 1E7HA 1H5WA 2Z8JA 1IJGA 2JUHA 3A73A 3NMUA 2NNWA 4LA0A 4ZCGA 5ID9A 4WA6B 3PLAA 1E7BA 4IW2A 2DBXA 1E7GA 1MIWA 4F5SA 2BX8A 2BXHA 1HA2A 1HK2A 1MUSA 1GNIA 2QMCA 4E99A 4W4UB 2LQHA 2BXOA 4FIPB 4I9OA 2EFDA 3ECPA 2KBZA 4IW1A 4GDXA 2AJEA 1E7IA 1UORA 1KDXA 2DYMA 4G03A 2BXMA 1J78A 2EFCA 4K2CA 4NAWB 4S1YA 3JRYA 5IFOA 3SIVB 2DBWA 2BXEA 2I2ZA 3WHQA 1MUHA 1E7AA 4F5VA 3GQUA 1MIYA 3TDLA 4LUFA 4G04A 3A75A 2XVVA 2EFHA 4GDKB 1N5UA 4Z9OA 5GHKA 3W1SA 1E78A 3BPJA 3LU8A 5B5TA 3M99C 4EMXA 5ID7A 4F5UA 4BKEA 2BXNA 3GQXA 5IIXA 2E0YA 4PO0A 4TQ0A 2BXDA 2Z8KA 1GNJA 2LQIA 3NVKA 1VFIA 3GA9L 2GUTA 1VZSA 2DG5A 4M70B 4G01A 3G9KD 2BXPA 2BXIA 5GIPA 4DM0A 5GINA 2CKXA 4L9KA 4N0FD 1LNSA 1BM0A 1O9XA 3NVMA 4ZBQA 4HGKA 4LB9A 4ZC6A 3V08A 2BXKA 4L8UA 5BPKA 1HK4A 3VQIA 2LOQA 5IIUA 1SB0A 2XW0A 3FNMA 1E7EA 4K71A 1E7CA 1AO6A 3KJLA 1BJ5A 4OTUA 1HK5A 1KXPD 2QM6A 5HOZA 3SQJA 2XMOA 5D7GA 3V09A 5IJEA 4GG2A 4C31B 3B9MA 4HGMB 3WHRA 4D7XA 1MM8A 4DHXB 2BXQA 2VUFA 4BY9C 4FJCB 2BXGA 4TQ1A 3WHSA 5FUOA 2E0XA 3H3AA 4LUHA 2BXFA 2LXSA 3V03A 1H9ZA 3CX9A 2VDBA 1KW2A 2KWFA 2XW1A 3KIKA 2QHBA 1LOTA 5DBYA 4FK5B 2I30A 1BKEA 2EFEA 1MIVA 2BXLA 2DBUA 4LB2A 1JNBA 1TXUA 2BXBA 2XVWA 4MBEC 1E7FA 1FOUA 2XVQA 4OT2A 1NT2B 2XVUA 2Z8IA 3MHHB 2BXAA 4J2VA 4N0UD 4OTTA 4OR0A 1TF0A 4ZBRA 1HK1A 1J7EA 5IJFA 3FWCC 4GDLB 3MHSB 2OZBB 4F5TA 3JQZA 4N3ZA 4JK4A 2NQOA 2VUEA 4ZUXV 3SIUB 3ICXA 3FWBC 2DYOA 2LXTA 5GIOA 1MA9A 5IJ5A 2YDFA 4ZBKA 3LU6A 2K0NA 2ROHA 3B9LA 5DQFA 3NVIA 3H37A 4Z69A
chains in the Genus database with same CATH topology

1HK3A 4L9QA 2BXCA 2OT3A 2V36A 3LU7A 5IIHA 3UIVA 2XSIA 1E7HA 1H5WA 2Z8JA 2JUHA 1IJGA 3A73A 3NMUA 2NNWA 4LA0A 4ZCGA 5ID9A 4WA6B 3PLAA 1E7BA 4IW2A 2DBXA 1E7GA 1MIWA 4F5SA 2BX8A 2BXHA 1HA2A 1HK2A 1GNIA 2QMCA 4E99A 4W4UB 2BXOA 4FIPB 2EFDA 2KBZA 4IW1A 4GDXA 2AJEA 1E7IA 1UORA 2DYMA 4G03A 2BXMA 1J78A 2EFCA 4K2CA 4NAWB 4S1YA 3JRYA 5IFOA 3SIVB 2DBWA 2BXEA 2I2ZA 3WHQA 1E7AA 4F5VA 3GQUA 1MIYA 3TDLA 4LUFA 4G04A 3A75A 2XVVA 2EFHA 4GDKB 1N5UA 4Z9OA 5GHKA 3W1SA 1E78A 3LU8A 5B5TA 3M99C 4EMXA 5ID7A 4F5UA 4BKEA 2BXNA 3GQXA 5IIXA 2E0YA 4PO0A 4TQ0A 2BXDA 2Z8KA 1GNJA 3NVKA 1VFIA 3GA9L 1VZSA 2DG5A 4M70B 4G01A 3G9KD 2BXPA 2BXIA 5GIPA 5GINA 2CKXA 4L9KA 4N0FD 1LNSA 1BM0A 1O9XA 3NVMA 4ZBQA 4HGKA 4LB9A 4ZC6A 3V08A 2BXKA 4L8UA 5BPKA 1HK4A 3VQIA 2LOQA 5IIUA 2XW0A 3FNMA 1E7EA 4K71A 1E7CA 1AO6A 3KJLA 1BJ5A 4OTUA 1HK5A 1KXPD 2QM6A 5HOZA 3SQJA 2XMOA 5D7GA 3V09A 5IJEA 4GG2A 4C31B 3B9MA 4HGMB 3WHRA 4DHXB 2BXQA 2VUFA 4BY9C 4FJCB 2BXGA 4TQ1A 3WHSA 5FUOA 2E0XA 3H3AA 4LUHA 2BXFA 3V03A 1H9ZA 3CX9A 2VDBA 1KW2A 2XW1A 2QHBA 3KIKA 1LOTA 5DBYA 4FK5B 2I30A 1BKEA 2EFEA 1MIVA 2BXLA 2DBUA 4LB2A 1JNBA 1TXUA 2BXBA 2XVWA 4MBEC 1E7FA 1FOUA 2XVQA 4OT2A 1NT2B 2XVUA 2Z8IA 3MHHB 2BXAA 4J2VA 4N0UD 4OTTA 4OR0A 1TF0A 4ZBRA 1HK1A 1J7EA 5IJFA 3FWCC 4GDLB 3MHSB 2OZBB 4F5TA 3JQZA 4N3ZA 4JK4A 2NQOA 2VUEA 4ZUXV 3SIUB 3ICXA 3FWBC 2DYOA 5GIOA 1MA9A 5IJ5A 2YDFA 4ZBKA 3LU6A 2ROHA 3B9LA 5DQFA 3NVIA 3H37A 4Z69A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1HK3 A;  4L9Q A;  2BXC A;  3LU7 A;  5IIH A;  3UIV A;  2XSI A;  1E7H A;  3A73 A;  4LA0 A;  5ID9 A;  1E7B A;  4IW2 A;  1E7G A;  4F5S A;  2BX8 A;  2BXH A;  1HA2 A;  1HK2 A;  1GNI A;  4E99 A;  2BXO A;  4IW1 A;  1E7I A;  1UOR A;  4G03 A;  2BXM A;  1J78 A;  4K2C A;  4S1Y A;  3JRY A;  5IFO A;  2BXE A;  2I2Z A;  1E7A A;  4F5V A;  3TDL A;  4LUF A;  4G04 A;  2XVV A;  1N5U A;  5GHK A;  1E78 A;  3LU8 A;  4EMX A;  5ID7 A;  4F5U A;  4BKE A;  2BXN A;  5IIX A;  4PO0 A;  2BXD A;  1GNJ A;  2BXP A;  2BXI A;  4L9K A;  4N0F D;  1BM0 A;  1O9X A;  4ZBQ A;  4HGK A;  4LB9 A;  3V08 A;  2BXK A;  4L8U A;  1HK4 A;  2XW0 A;  4K71 A;  1E7E A;  1E7C A;  1AO6 A;  1BJ5 A;  1HK5 A;  1KXP D;  5HOZ A;  3SQJ A;  5IJE A;  3V09 A;  3B9M A;  4HGM B;  2BXQ A;  2VUF A;  2BXG A;  5FUO A;  4LUH A;  2BXF A;  3V03 A;  1H9Z A;  3CX9 A;  2VDB A;  1KW2 A;  2XW1 A;  1LOT A;  5DBY A;  2I30 A;  1BKE A;  2BXL A;  5IIU A;  4LB2 A;  2XVW A;  2BXB A;  1E7F A;  2XVQ A;  4OT2 A;  2XVU A;  4J2V A;  2BXA A;  4N0U D;  4OR0 A;  1TF0 A;  4ZBR A;  1HK1 A;  1J7E A;  5IJF A;  4F5T A;  3JQZ A;  4JK4 A;  2VUE A;  1MA9 A;  5IJ5 A;  2YDF A;  3LU6 A;  3B9L A;  5DQF A;  4Z69 A; 
#chains in the Genus database with same CATH topology
 2AGH B;  1HK3 A;  4L9Q A;  2BXC A;  2OT3 A;  2V36 A;  3LU7 A;  5IIH A;  3UIV A;  2XSI A;  1E7H A;  1H5W A;  2Z8J A;  1IJG A;  2JUH A;  3A73 A;  3NMU A;  2NNW A;  4LA0 A;  4ZCG A;  5ID9 A;  4WA6 B;  3PLA A;  1E7B A;  4IW2 A;  2DBX A;  1E7G A;  1MIW A;  4F5S A;  2BX8 A;  2BXH A;  1HA2 A;  1HK2 A;  1MUS A;  1GNI A;  2QMC A;  4E99 A;  4W4U B;  2LQH A;  2BXO A;  4FIP B;  4I9O A;  2EFD A;  3ECP A;  2KBZ A;  4IW1 A;  4GDX A;  2AJE A;  1E7I A;  1UOR A;  1KDX A;  2DYM A;  4G03 A;  2BXM A;  1J78 A;  2EFC A;  4K2C A;  4NAW B;  4S1Y A;  3JRY A;  5IFO A;  3SIV B;  2DBW A;  2BXE A;  2I2Z A;  3WHQ A;  1MUH A;  1E7A A;  4F5V A;  3GQU A;  1MIY A;  3TDL A;  4LUF A;  4G04 A;  3A75 A;  2XVV A;  2EFH A;  4GDK B;  1N5U A;  4Z9O A;  5GHK A;  3W1S A;  1E78 A;  3BPJ A;  3LU8 A;  5B5T A;  3M99 C;  4EMX A;  5ID7 A;  4F5U A;  4BKE A;  2BXN A;  3GQX A;  5IIX A;  2E0Y A;  4PO0 A;  4TQ0 A;  2BXD A;  2Z8K A;  1GNJ A;  2LQI A;  3NVK A;  1VFI A;  3GA9 L;  2GUT A;  1VZS A;  2DG5 A;  4M70 B;  4G01 A;  3G9K D;  2BXP A;  2BXI A;  5GIP A;  4DM0 A;  5GIN A;  2CKX A;  4L9K A;  4N0F D;  1LNS A;  1BM0 A;  1O9X A;  3NVM A;  4ZBQ A;  4HGK A;  4LB9 A;  4ZC6 A;  3V08 A;  2BXK A;  4L8U A;  5BPK A;  1HK4 A;  3VQI A;  2LOQ A;  5IIU A;  1SB0 A;  2XW0 A;  3FNM A;  1E7E A;  4K71 A;  1E7C A;  1AO6 A;  3KJL A;  1BJ5 A;  4OTU A;  1HK5 A;  1KXP D;  2QM6 A;  5HOZ A;  3SQJ A;  2XMO A;  5D7G A;  3V09 A;  5IJE A;  4GG2 A;  4C31 B;  3B9M A;  4HGM B;  3WHR A;  4D7X A;  1MM8 A;  4DHX B;  2BXQ A;  2VUF A;  4BY9 C;  4FJC B;  2BXG A;  4TQ1 A;  3WHS A;  5FUO A;  2E0X A;  3H3A A;  4LUH A;  2BXF A;  2LXS A;  3V03 A;  1H9Z A;  3CX9 A;  2VDB A;  1KW2 A;  2KWF A;  2XW1 A;  3KIK A;  2QHB A;  1LOT A;  5DBY A;  4FK5 B;  2I30 A;  1BKE A;  2EFE A;  1MIV A;  2BXL A;  2DBU A;  4LB2 A;  1JNB A;  1TXU A;  2BXB A;  2XVW A;  4MBE C;  1E7F A;  1FOU A;  2XVQ A;  4OT2 A;  1NT2 B;  2XVU A;  2Z8I A;  3MHH B;  2BXA A;  4J2V A;  4N0U D;  4OTT A;  4OR0 A;  1TF0 A;  4ZBR A;  1HK1 A;  1J7E A;  5IJF A;  3FWC C;  4GDL B;  3MHS B;  2OZB B;  4F5T A;  3JQZ A;  4N3Z A;  4JK4 A;  2NQO A;  2VUE A;  4ZUX V;  3SIU B;  3ICX A;  3FWB C;  2DYO A;  2LXT A;  5GIO A;  1MA9 A;  5IJ5 A;  2YDF A;  4ZBK A;  3LU6 A;  2K0N A;  2ROH A;  3B9L A;  5DQF A;  3NVI A;  3H37 A;  4Z69 A; 
#chains in the Genus database with same CATH homology
 1HK3 A;  4L9Q A;  2BXC A;  2OT3 A;  2V36 A;  3LU7 A;  5IIH A;  3UIV A;  2XSI A;  1E7H A;  1H5W A;  2Z8J A;  2JUH A;  1IJG A;  3A73 A;  3NMU A;  2NNW A;  4LA0 A;  4ZCG A;  5ID9 A;  4WA6 B;  3PLA A;  1E7B A;  4IW2 A;  2DBX A;  1E7G A;  1MIW A;  4F5S A;  2BX8 A;  2BXH A;  1HA2 A;  1HK2 A;  1GNI A;  2QMC A;  4E99 A;  4W4U B;  2BXO A;  4FIP B;  2EFD A;  2KBZ A;  4IW1 A;  4GDX A;  2AJE A;  1E7I A;  1UOR A;  2DYM A;  4G03 A;  2BXM A;  1J78 A;  2EFC A;  4K2C A;  4NAW B;  4S1Y A;  3JRY A;  5IFO A;  3SIV B;  2DBW A;  2BXE A;  2I2Z A;  3WHQ A;  1E7A A;  4F5V A;  3GQU A;  1MIY A;  3TDL A;  4LUF A;  4G04 A;  3A75 A;  2XVV A;  2EFH A;  4GDK B;  1N5U A;  4Z9O A;  5GHK A;  3W1S A;  1E78 A;  3LU8 A;  5B5T A;  3M99 C;  4EMX A;  5ID7 A;  4F5U A;  4BKE A;  2BXN A;  3GQX A;  5IIX A;  2E0Y A;  4PO0 A;  4TQ0 A;  2BXD A;  2Z8K A;  1GNJ A;  3NVK A;  1VFI A;  3GA9 L;  1VZS A;  2DG5 A;  4M70 B;  4G01 A;  3G9K D;  2BXP A;  2BXI A;  5GIP A;  5GIN A;  2CKX A;  4L9K A;  4N0F D;  1LNS A;  1BM0 A;  1O9X A;  3NVM A;  4ZBQ A;  4HGK A;  4LB9 A;  4ZC6 A;  3V08 A;  2BXK A;  4L8U A;  5BPK A;  1HK4 A;  3VQI A;  2LOQ A;  5IIU A;  2XW0 A;  3FNM A;  1E7E A;  4K71 A;  1E7C A;  1AO6 A;  3KJL A;  1BJ5 A;  4OTU A;  1HK5 A;  1KXP D;  2QM6 A;  5HOZ A;  3SQJ A;  2XMO A;  5D7G A;  3V09 A;  5IJE A;  4GG2 A;  4C31 B;  3B9M A;  4HGM B;  3WHR A;  4DHX B;  2BXQ A;  2VUF A;  4BY9 C;  4FJC B;  2BXG A;  4TQ1 A;  3WHS A;  5FUO A;  2E0X A;  3H3A A;  4LUH A;  2BXF A;  3V03 A;  1H9Z A;  3CX9 A;  2VDB A;  1KW2 A;  2XW1 A;  2QHB A;  3KIK A;  1LOT A;  5DBY A;  4FK5 B;  2I30 A;  1BKE A;  2EFE A;  1MIV A;  2BXL A;  2DBU A;  4LB2 A;  1JNB A;  1TXU A;  2BXB A;  2XVW A;  4MBE C;  1E7F A;  1FOU A;  2XVQ A;  4OT2 A;  1NT2 B;  2XVU A;  2Z8I A;  3MHH B;  2BXA A;  4J2V A;  4N0U D;  4OTT A;  4OR0 A;  1TF0 A;  4ZBR A;  1HK1 A;  1J7E A;  5IJF A;  3FWC C;  4GDL B;  3MHS B;  2OZB B;  4F5T A;  3JQZ A;  4N3Z A;  4JK4 A;  2NQO A;  2VUE A;  4ZUX V;  3SIU B;  3ICX A;  3FWB C;  2DYO A;  5GIO A;  1MA9 A;  5IJ5 A;  2YDF A;  4ZBK A;  3LU6 A;  2ROH A;  3B9L A;  5DQF A;  3NVI A;  3H37 A;  4Z69 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2BXKA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations