2BXLA

Human serum albumin complexed with myristate and 3,5-diiodosalicylic acid
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
581
structure length
581
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 224
structure length 581
sequence length 581
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxlA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxlA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxlA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxlA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxlA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxlA05
2YDFA 3V08A 3JQZA 4S1YA 2VDBA 4LUFA 2BXDA 2XVVA 3A73A 4PO0A 3V09A 1E78A 3B9MA 5ID9A 1BJ5A 4LB9A 1HK4A 3UIVA 1GNIA 1N5UA 4LB2A 5DBYA 1E7GA 3JRYA 4JK4A 1E7CA 1GNJA 5HOZA 4L9QA 4LA0A 2BXGA 2XSIA 2BXKA 4F5UA 3LU7A 2BXLA 5FUOA 4F5TA 1J7EA 4N0UD 5IIXA 4OT2A 3SQJA 1KXPD 2BXPA 5IIHA 2BX8A 2I2ZA 4ZBRA 1E7AA 2BXFA 4L8UA 4Z69A 1HK5A 4IW2A 1HA2A 2BXEA 1E7HA 2BXOA 4K71A 4LUHA 2XW0A 4J2VA 5IIUA 5ID7A 4N0FD 1TF0A 3TDLA 1KW2A 2BXMA 2BXAA 2I30A 1H9ZA 2VUEA 1BM0A 2XVWA 1E7BA 4K2CA 2BXCA 4G04A 1MA9A 5DQFA 2BXIA 1J78A 5IJ5A 4BKEA 2BXHA 3LU8A 2BXBA 4G03A 4E99A 3CX9A 4IW1A 1E7FA 1HK3A 2BXNA 2XVQA 3B9LA 1UORA 2BXQA 4L9KA 1E7IA 1AO6A 1E7EA 4F5VA 2XW1A 5IJEA 1O9XA 5GHKA 5IFOA 3LU6A 4OR0A 1BKEA 1HK1A 4HGMB 4F5SA 2XVUA 1LOTA 1HK2A 4EMXA 3V03A 5IJFA 4ZBQA 2VUFA 4HGKA
chains in the Genus database with same CATH superfamily
3FWCC 2OT3A 2CKXA 2YDFA 3V08A 3JQZA 4GDKB 4ZCGA 3FWBC 4S1YA 2VDBA 4LUFA 4GDXA 3BPJA 4NAWB 2BXDA 2XVVA 2LOQA 3A73A 1MUSA 3NVIA 2DBWA 4PO0A 3V09A 5GINA 1E78A 2DBUA 3B9MA 5ID9A 1LNSA 1BJ5A 5GIPA 3GQUA 4D7XA 4LB9A 4HGKA 1HK4A 2EFCA 1VFIA 1MM8A 1FOUA 3UIVA 1GNIA 2DYMA 3GQXA 3WHRA 5GIOA 1JNBA 1N5UA 3A75A 4LB2A 5DBYA 4OTTA 2XMOA 1E7GA 3JRYA 4JK4A 3NVMA 4ZUXV 4I9OA 1E7CA 1MIVA 3GA9L 2QHBA 1GNJA 5HOZA 2K0NA 4L9QA 4LA0A 2BXGA 3WHSA 2EFHA 1MIWA 3KIKA 2XSIA 2BXKA 4F5UA 2LQHA 2BXLA 3LU7A 5FUOA 3NMUA 4F5TA 2E0YA 1J7EA 4TQ1A 2NQOA 4N0UD 4C31B 5IIXA 4OT2A 3SQJA 1KXPD 2BXPA 4TQ0A 5IIHA 2BX8A 2I2ZA 2DBXA 2LXTA 4ZBRA 4OTUA 1E7AA 5B5TA 2ROHA 4WA6B 4GDLB 3G9KD 2BXFA 4L8UA 4Z69A 1HK5A 3ICXA 2EFDA 3KJLA 3SIUB 4IW2A 1HA2A 2BXEA 1E7HA 4MBEC 3SIVB 2BXOA 4DHXB 4K71A 4LUHA 3M99C 5BPKA 2Z8JA 3MHSB 2XW0A 2KBZA 1SB0A 2QMCA 4J2VA 5IIUA 5ID7A 4N0FD 1TF0A 3TDLA 1KW2A 4BY9C 2BXMA 2AJEA 1MIYA 4FIPB 2BXAA 4FK5B 2I30A 2AGHB 1H9ZA 2V36A 2VUEA 2NNWA 2QM6A 1BM0A 2XVWA 1E7BA 3FNMA 3VQIA 4K2CA 4G01A 2BXCA 4G04A 1MA9A 5DQFA 3PLAA 2BXIA 1J78A 4Z9OA 5IJ5A 4BKEA 4DM0A 2Z8KA 2BXHA 1MUHA 3LU8A 2LQIA 4N3ZA 3H37A 2BXBA 4G03A 4E99A 2GUTA 4ZC6A 3CX9A 3WHQA 1TXUA 4IW1A 3H3AA 1E7FA 4ZBKA 1HK3A 2BXNA 5D7GA 2XVQA 4GG2A 3W1SA 3B9LA 2DG5A 1UORA 2BXQA 4L9KA 2DYOA 2KWFA 3ECPA 1E7IA 1KDXA 1AO6A 2EFEA 1E7EA 4F5VA 2OZBB 2XW1A 3NVKA 1VZSA 5IJEA 1O9XA 2Z8IA 5GHKA 5IFOA 3LU6A 4OR0A 1BKEA 1HK1A 1IJGA 4W4UB 4HGMB 4F5SA 2LXSA 2XVUA 4FJCB 1NT2B 1LOTA 1H5WA 2E0XA 1HK2A 2JUHA 4EMXA 3V03A 5IJFA 4M70B 4ZBQA 2VUFA 3MHHB
chains in the Genus database with same CATH topology
3FWCC 2OT3A 2CKXA 2YDFA 3V08A 3JQZA 4GDKB 4ZCGA 3FWBC 4S1YA 2VDBA 4LUFA 4GDXA 4NAWB 2BXDA 2XVVA 2LOQA 3A73A 3NVIA 2DBWA 4PO0A 3V09A 5GINA 1E78A 2DBUA 3B9MA 5ID9A 1LNSA 1BJ5A 5GIPA 3GQUA 4LB9A 4HGKA 1HK4A 2EFCA 1VFIA 1FOUA 3UIVA 1GNIA 2DYMA 3GQXA 3WHRA 5GIOA 1JNBA 1N5UA 3A75A 4LB2A 5DBYA 4OTTA 2XMOA 1E7GA 3JRYA 4JK4A 3NVMA 4ZUXV 1E7CA 1MIVA 3GA9L 2QHBA 1GNJA 5HOZA 4L9QA 4LA0A 2BXGA 3WHSA 2EFHA 1MIWA 3KIKA 2XSIA 2BXKA 4F5UA 3LU7A 2BXLA 5FUOA 3NMUA 4F5TA 2E0YA 1J7EA 4TQ1A 2NQOA 4N0UD 4C31B 5IIXA 4OT2A 3SQJA 1KXPD 2BXPA 4TQ0A 5IIHA 2BX8A 2I2ZA 2DBXA 4ZBRA 4OTUA 1E7AA 5B5TA 2ROHA 4WA6B 4GDLB 3G9KD 2BXFA 4L8UA 4Z69A 1HK5A 3ICXA 2EFDA 3KJLA 3SIUB 4IW2A 1HA2A 2BXEA 1E7HA 4MBEC 3SIVB 2BXOA 4DHXB 4K71A 4LUHA 3M99C 5BPKA 2Z8JA 3MHSB 2XW0A 2KBZA 2QMCA 4J2VA 5IIUA 5ID7A 4N0FD 1TF0A 3TDLA 1KW2A 4BY9C 2BXMA 2AJEA 1MIYA 4FIPB 2BXAA 4FK5B 2I30A 1H9ZA 2V36A 2VUEA 2NNWA 2QM6A 1BM0A 2XVWA 1E7BA 3FNMA 3VQIA 4K2CA 4G01A 2BXCA 4G04A 1MA9A 5DQFA 3PLAA 2BXIA 1J78A 4Z9OA 5IJ5A 4BKEA 2Z8KA 2BXHA 3LU8A 4N3ZA 3H37A 2BXBA 4G03A 4E99A 4ZC6A 3CX9A 3WHQA 1TXUA 4IW1A 3H3AA 1E7FA 4ZBKA 1HK3A 2BXNA 5D7GA 2XVQA 4GG2A 3W1SA 3B9LA 2DG5A 1UORA 2BXQA 4L9KA 2DYOA 1E7IA 1AO6A 2EFEA 1E7EA 4F5VA 2OZBB 2XW1A 3NVKA 1VZSA 5IJEA 1O9XA 2Z8IA 5GHKA 5IFOA 3LU6A 4OR0A 1BKEA 1HK1A 1IJGA 4W4UB 4HGMB 4F5SA 2XVUA 4FJCB 1NT2B 1LOTA 1H5WA 2E0XA 1HK2A 2JUHA 4EMXA 3V03A 5IJFA 4M70B 4ZBQA 2VUFA 3MHHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YDF A;  3V08 A;  3JQZ A;  4S1Y A;  2VDB A;  4LUF A;  2BXD A;  2XVV A;  3A73 A;  4PO0 A;  3V09 A;  1E78 A;  3B9M A;  5ID9 A;  1BJ5 A;  4LB9 A;  1HK4 A;  3UIV A;  1GNI A;  1N5U A;  4LB2 A;  5DBY A;  1E7G A;  3JRY A;  4JK4 A;  1E7C A;  1GNJ A;  5HOZ A;  4L9Q A;  4LA0 A;  2BXG A;  2XSI A;  2BXK A;  4F5U A;  3LU7 A;  2BXL A;  5FUO A;  4F5T A;  1J7E A;  4N0U D;  5IIX A;  4OT2 A;  3SQJ A;  1KXP D;  2BXP A;  5IIH A;  2BX8 A;  2I2Z A;  4ZBR A;  1E7A A;  2BXF A;  4L8U A;  4Z69 A;  1HK5 A;  4IW2 A;  1HA2 A;  2BXE A;  1E7H A;  2BXO A;  4K71 A;  4LUH A;  2XW0 A;  4J2V A;  5IIU A;  5ID7 A;  4N0F D;  1TF0 A;  3TDL A;  1KW2 A;  2BXM A;  2BXA A;  2I30 A;  1H9Z A;  2VUE A;  1BM0 A;  2XVW A;  1E7B A;  4K2C A;  2BXC A;  4G04 A;  1MA9 A;  5DQF A;  2BXI A;  1J78 A;  5IJ5 A;  4BKE A;  2BXH A;  3LU8 A;  2BXB A;  4G03 A;  4E99 A;  3CX9 A;  4IW1 A;  1E7F A;  1HK3 A;  2BXN A;  2XVQ A;  3B9L A;  1UOR A;  2BXQ A;  4L9K A;  1E7I A;  1AO6 A;  1E7E A;  4F5V A;  2XW1 A;  5IJE A;  1O9X A;  5GHK A;  5IFO A;  3LU6 A;  4OR0 A;  1BKE A;  1HK1 A;  4HGM B;  4F5S A;  2XVU A;  1LOT A;  1HK2 A;  4EMX A;  3V03 A;  5IJF A;  4ZBQ A;  2VUF A;  4HGK A; 
#chains in the Genus database with same CATH topology
 3FWC C;  2OT3 A;  2CKX A;  2YDF A;  3V08 A;  3JQZ A;  4GDK B;  4ZCG A;  3FWB C;  4S1Y A;  2VDB A;  4LUF A;  4GDX A;  3BPJ A;  4NAW B;  2BXD A;  2XVV A;  2LOQ A;  3A73 A;  1MUS A;  3NVI A;  2DBW A;  4PO0 A;  3V09 A;  5GIN A;  1E78 A;  2DBU A;  3B9M A;  5ID9 A;  1LNS A;  1BJ5 A;  5GIP A;  3GQU A;  4D7X A;  4LB9 A;  4HGK A;  1HK4 A;  2EFC A;  1VFI A;  1MM8 A;  1FOU A;  3UIV A;  1GNI A;  2DYM A;  3GQX A;  3WHR A;  5GIO A;  1JNB A;  1N5U A;  3A75 A;  4LB2 A;  5DBY A;  4OTT A;  2XMO A;  1E7G A;  3JRY A;  4JK4 A;  3NVM A;  4ZUX V;  4I9O A;  1E7C A;  1MIV A;  3GA9 L;  2QHB A;  1GNJ A;  5HOZ A;  2K0N A;  4L9Q A;  4LA0 A;  2BXG A;  3WHS A;  2EFH A;  1MIW A;  3KIK A;  2XSI A;  2BXK A;  4F5U A;  2LQH A;  2BXL A;  3LU7 A;  5FUO A;  3NMU A;  4F5T A;  2E0Y A;  1J7E A;  4TQ1 A;  2NQO A;  4N0U D;  4C31 B;  5IIX A;  4OT2 A;  3SQJ A;  1KXP D;  2BXP A;  4TQ0 A;  5IIH A;  2BX8 A;  2I2Z A;  2DBX A;  2LXT A;  4ZBR A;  4OTU A;  1E7A A;  5B5T A;  2ROH A;  4WA6 B;  4GDL B;  3G9K D;  2BXF A;  4L8U A;  4Z69 A;  1HK5 A;  3ICX A;  2EFD A;  3KJL A;  3SIU B;  4IW2 A;  1HA2 A;  2BXE A;  1E7H A;  4MBE C;  3SIV B;  2BXO A;  4DHX B;  4K71 A;  4LUH A;  3M99 C;  5BPK A;  2Z8J A;  3MHS B;  2XW0 A;  2KBZ A;  1SB0 A;  2QMC A;  4J2V A;  5IIU A;  5ID7 A;  4N0F D;  1TF0 A;  3TDL A;  1KW2 A;  4BY9 C;  2BXM A;  2AJE A;  1MIY A;  4FIP B;  2BXA A;  4FK5 B;  2I30 A;  2AGH B;  1H9Z A;  2V36 A;  2VUE A;  2NNW A;  2QM6 A;  1BM0 A;  2XVW A;  1E7B A;  3FNM A;  3VQI A;  4K2C A;  4G01 A;  2BXC A;  4G04 A;  1MA9 A;  5DQF A;  3PLA A;  2BXI A;  1J78 A;  4Z9O A;  5IJ5 A;  4BKE A;  4DM0 A;  2Z8K A;  2BXH A;  1MUH A;  3LU8 A;  2LQI A;  4N3Z A;  3H37 A;  2BXB A;  4G03 A;  4E99 A;  2GUT A;  4ZC6 A;  3CX9 A;  3WHQ A;  1TXU A;  4IW1 A;  3H3A A;  1E7F A;  4ZBK A;  1HK3 A;  2BXN A;  5D7G A;  2XVQ A;  4GG2 A;  3W1S A;  3B9L A;  2DG5 A;  1UOR A;  2BXQ A;  4L9K A;  2DYO A;  2KWF A;  3ECP A;  1E7I A;  1KDX A;  1AO6 A;  2EFE A;  1E7E A;  4F5V A;  2OZB B;  2XW1 A;  3NVK A;  1VZS A;  5IJE A;  1O9X A;  2Z8I A;  5GHK A;  5IFO A;  3LU6 A;  4OR0 A;  1BKE A;  1HK1 A;  1IJG A;  4W4U B;  4HGM B;  4F5S A;  2LXS A;  2XVU A;  4FJC B;  1NT2 B;  1LOT A;  1H5W A;  2E0X A;  1HK2 A;  2JUH A;  4EMX A;  3V03 A;  5IJF A;  4M70 B;  4ZBQ A;  2VUF A;  3MHH B; 
#chains in the Genus database with same CATH homology
 3FWC C;  2OT3 A;  2CKX A;  2YDF A;  3V08 A;  3JQZ A;  4GDK B;  4ZCG A;  3FWB C;  4S1Y A;  2VDB A;  4LUF A;  4GDX A;  4NAW B;  2BXD A;  2XVV A;  2LOQ A;  3A73 A;  3NVI A;  2DBW A;  4PO0 A;  3V09 A;  5GIN A;  1E78 A;  2DBU A;  3B9M A;  5ID9 A;  1LNS A;  1BJ5 A;  5GIP A;  3GQU A;  4LB9 A;  4HGK A;  1HK4 A;  2EFC A;  1VFI A;  1FOU A;  3UIV A;  1GNI A;  2DYM A;  3GQX A;  3WHR A;  5GIO A;  1JNB A;  1N5U A;  3A75 A;  4LB2 A;  5DBY A;  4OTT A;  2XMO A;  1E7G A;  3JRY A;  4JK4 A;  3NVM A;  4ZUX V;  1E7C A;  1MIV A;  3GA9 L;  2QHB A;  1GNJ A;  5HOZ A;  4L9Q A;  4LA0 A;  2BXG A;  3WHS A;  2EFH A;  1MIW A;  3KIK A;  2XSI A;  2BXK A;  4F5U A;  3LU7 A;  2BXL A;  5FUO A;  3NMU A;  4F5T A;  2E0Y A;  1J7E A;  4TQ1 A;  2NQO A;  4N0U D;  4C31 B;  5IIX A;  4OT2 A;  3SQJ A;  1KXP D;  2BXP A;  4TQ0 A;  5IIH A;  2BX8 A;  2I2Z A;  2DBX A;  4ZBR A;  4OTU A;  1E7A A;  5B5T A;  2ROH A;  4WA6 B;  4GDL B;  3G9K D;  2BXF A;  4L8U A;  4Z69 A;  1HK5 A;  3ICX A;  2EFD A;  3KJL A;  3SIU B;  4IW2 A;  1HA2 A;  2BXE A;  1E7H A;  4MBE C;  3SIV B;  2BXO A;  4DHX B;  4K71 A;  4LUH A;  3M99 C;  5BPK A;  2Z8J A;  3MHS B;  2XW0 A;  2KBZ A;  2QMC A;  4J2V A;  5IIU A;  5ID7 A;  4N0F D;  1TF0 A;  3TDL A;  1KW2 A;  4BY9 C;  2BXM A;  2AJE A;  1MIY A;  4FIP B;  2BXA A;  4FK5 B;  2I30 A;  1H9Z A;  2V36 A;  2VUE A;  2NNW A;  2QM6 A;  1BM0 A;  2XVW A;  1E7B A;  3FNM A;  3VQI A;  4K2C A;  4G01 A;  2BXC A;  4G04 A;  1MA9 A;  5DQF A;  3PLA A;  2BXI A;  1J78 A;  4Z9O A;  5IJ5 A;  4BKE A;  2Z8K A;  2BXH A;  3LU8 A;  4N3Z A;  3H37 A;  2BXB A;  4G03 A;  4E99 A;  4ZC6 A;  3CX9 A;  3WHQ A;  1TXU A;  4IW1 A;  3H3A A;  1E7F A;  4ZBK A;  1HK3 A;  2BXN A;  5D7G A;  2XVQ A;  4GG2 A;  3W1S A;  3B9L A;  2DG5 A;  1UOR A;  2BXQ A;  4L9K A;  2DYO A;  1E7I A;  1AO6 A;  2EFE A;  1E7E A;  4F5V A;  2OZB B;  2XW1 A;  3NVK A;  1VZS A;  5IJE A;  1O9X A;  2Z8I A;  5GHK A;  5IFO A;  3LU6 A;  4OR0 A;  1BKE A;  1HK1 A;  1IJG A;  4W4U B;  4HGM B;  4F5S A;  2XVU A;  4FJC B;  1NT2 B;  1LOT A;  1H5W A;  2E0X A;  1HK2 A;  2JUH A;  4EMX A;  3V03 A;  5IJF A;  4M70 B;  4ZBQ A;  2VUF A;  3MHH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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