2BXM | Genus

Total Genus 225

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	225
sequence length	582
structure length	582
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transport protein
source organism	Homo sapiens
publication title	Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	225
structure length	582
sequence length	582
ec nomenclature
pdb deposition date	2005-07-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxmA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxmA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxmA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxmA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxmA06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxmA05

2I2ZA 2BXEA 3UIVA 1HA2A 4K71A 5GHKA 2VDBA 3B9MA 2BXFA 4J2VA 4G04A 5DQFA 2I30A 1HK2A 3JRYA 2BXLA 4HGKA 2BXMA 1E7BA 1E7CA 2VUEA 1E7IA 2XSIA 5FUOA 2VUFA 1E7HA 5IJEA 2XW1A 4BKEA 1GNJA 4EMXA 4JK4A 3V09A 4F5SA 1AO6A 5IIUA 1N5UA 3A73A 3V08A 1HK4A 2BXCA 4F5UA 1HK5A 5ID9A 4N0UD 4LUHA 5IJFA 5IIHA 1MA9A 4LB9A 1J78A 1TF0A 1UORA 3LU7A 4PO0A 2BXAA 2BXDA 2BXHA 4OR0A 3TDLA 4LA0A 4L9QA 1HK1A 4LUFA 1BKEA 4HGMB 5IFOA 2BXQA 1HK3A 3CX9A 4E99A 4Z69A 1KW2A 5DBYA 2BXPA 1E7EA 2XVUA 2BXOA 1GNIA 2XW0A 1KXPD 2BXNA 2XVWA 2BX8A 3B9LA 4L9KA 2BXKA 2BXGA 3SQJA 2BXIA 3JQZA 1E7GA 5IJ5A 4K2CA 1O9XA 4OT2A 2YDFA 4F5VA 2BXBA 1LOTA 4G03A 1E78A 1H9ZA 2XVQA 4N0FD 4ZBQA 1E7AA 1J7EA 1BJ5A 4IW2A 3LU8A 4ZBRA 5HOZA 2XVVA 4F5TA 1E7FA 4S1YA 4L8UA 4IW1A 3LU6A 3V03A 5IIXA 4LB2A 5ID7A 1BM0A
chains in the Genus database with same CATH superfamily

2I2ZA 4GDKB 1H5WA 2BXEA 3UIVA 1HA2A 1VZSA 4K71A 5GHKA 2VDBA 3B9MA 2JUHA 3GQUA 1LNSA 2BXFA 4DM0A 4I9OA 4J2VA 2DBUA 4G04A 4W4UB 2I30A 5DQFA 1HK2A 2DYMA 3JRYA 1MM8A 2QMCA 3SIVB 2BXLA 4ZBKA 3SIUB 2ROHA 4HGKA 3PLAA 2AJEA 1MIWA 3M99C 2BXMA 1E7BA 1MUHA 4ZCGA 3NVIA 1E7CA 2VUEA 1E7IA 2XSIA 5FUOA 5GIPA 3H37A 4GG2A 2VUFA 1E7HA 5IJEA 2XW1A 4BKEA 1GNJA 3FNMA 4EMXA 4JK4A 2NQOA 3V09A 4F5SA 4D7XA 3H3AA 4Z9OA 1AO6A 2AGHB 2OZBB 5IIUA 1MIVA 3NVKA 1N5UA 2CKXA 3A73A 2E0XA 3V08A 4N3ZA 2GUTA 1HK4A 2BXCA 4F5UA 2EFEA 1HK5A 5ID9A 2EFHA 4N0UD 2QHBA 4GDLB 4DHXB 4LUHA 2XMOA 5IIHA 5IJFA 1MA9A 3FWBC 2Z8JA 4LB9A 5D7GA 1J78A 1TF0A 4OTUA 1UORA 1NT2B 2EFCA 3LU7A 2LQHA 3MHSB 4PO0A 1MIYA 3W1SA 3VQIA 2BXAA 4G01A 5GIOA 2BXDA 2BXHA 4TQ0A 4TQ1A 5GINA 2DYOA 4OR0A 3TDLA 4LA0A 3G9KD 4L9QA 1HK1A 4LUFA 1BKEA 4FIPB 4HGMB 2BXQA 1HK3A 5IFOA 3CX9A 4E99A 4Z69A 1KW2A 2Z8KA 3ICXA 3WHQA 5DBYA 4MBEC 3NVMA 2BXPA 1E7EA 2XVUA 2LOQA 2BXOA 1GNIA 1JNBA 2XW0A 2NNWA 1KXPD 2BXNA 3ECPA 1SB0A 2XVWA 4BY9C 2BX8A 2V36A 4FK5B 1MUSA 3B9LA 4L9KA 2BXKA 2BXGA 3SQJA 2BXIA 3JQZA 1E7GA 2LXTA 5IJ5A 3GQXA 3NMUA 1TXUA 4K2CA 1O9XA 4OT2A 4WA6B 2E0YA 2LXSA 2YDFA 3MHHB 4ZUXV 4F5VA 2BXBA 3KJLA 1LOTA 4G03A 1E78A 1H9ZA 2KWFA 1KDXA 2XVQA 4N0FD 2Z8IA 3A75A 4M70B 1E7AA 4ZBQA 2DBWA 1J7EA 1BJ5A 2EFDA 4IW2A 1IJGA 3LU8A 3GA9L 4ZBRA 3KIKA 5HOZA 4NAWB 2XVVA 4F5TA 1E7FA 2DG5A 2QM6A 3BPJA 4S1YA 5BPKA 4L8UA 4ZC6A 4IW1A 2LQIA 4GDXA 3LU6A 3V03A 4FJCB 5IIXA 4LB2A 3WHRA 1FOUA 2KBZA 2OT3A 5ID7A 1VFIA 2K0NA 4OTTA 5B5TA 3FWCC 2DBXA 3WHSA 4C31B 1BM0A
chains in the Genus database with same CATH topology

2I2ZA 4GDKB 1H5WA 2BXEA 3UIVA 1HA2A 1VZSA 4K71A 5GHKA 2VDBA 3B9MA 2JUHA 3GQUA 1LNSA 2BXFA 4J2VA 4W4UB 2DBUA 4G04A 5DQFA 2I30A 1HK2A 2DYMA 3JRYA 3SIVB 2QMCA 2BXLA 4ZBKA 3SIUB 2ROHA 4HGKA 3PLAA 2AJEA 1MIWA 3M99C 2BXMA 1E7BA 4ZCGA 3NVIA 1E7CA 2VUEA 1E7IA 2XSIA 5FUOA 5GIPA 3H37A 4GG2A 2VUFA 1E7HA 5IJEA 2XW1A 4BKEA 1GNJA 3FNMA 4EMXA 4JK4A 2NQOA 3V09A 4F5SA 3H3AA 4Z9OA 1AO6A 2OZBB 5IIUA 1MIVA 3NVKA 1N5UA 2CKXA 3A73A 2E0XA 3V08A 4N3ZA 1HK4A 2BXCA 4F5UA 2EFEA 1HK5A 5ID9A 2EFHA 4N0UD 2QHBA 4GDLB 4DHXB 4LUHA 2XMOA 5IIHA 5IJFA 1MA9A 3FWBC 2Z8JA 4LB9A 5D7GA 1J78A 1TF0A 4OTUA 1UORA 1NT2B 2EFCA 3LU7A 3MHSB 4PO0A 1MIYA 3W1SA 3VQIA 2BXAA 4G01A 5GIOA 2BXDA 2BXHA 4TQ0A 4TQ1A 5GINA 2DYOA 4OR0A 3TDLA 4LA0A 3G9KD 4L9QA 1HK1A 4LUFA 1BKEA 4FIPB 4HGMB 2BXQA 1HK3A 5IFOA 3CX9A 4E99A 4Z69A 1KW2A 2Z8KA 3ICXA 3WHQA 5DBYA 4MBEC 3NVMA 2BXPA 1E7EA 2XVUA 2LOQA 2BXOA 1GNIA 1JNBA 2XW0A 2NNWA 1KXPD 2BXNA 2XVWA 4BY9C 2BX8A 2V36A 4FK5B 3B9LA 4L9KA 2BXKA 2BXGA 3SQJA 2BXIA 3JQZA 1E7GA 3NMUA 5IJ5A 3GQXA 1TXUA 4K2CA 1O9XA 4OT2A 4WA6B 2E0YA 2YDFA 3MHHB 4ZUXV 4F5VA 2BXBA 3KJLA 1LOTA 4G03A 1E78A 1H9ZA 2XVQA 4N0FD 2Z8IA 3A75A 4M70B 1E7AA 4ZBQA 2DBWA 1J7EA 1BJ5A 2EFDA 4IW2A 1IJGA 3LU8A 3GA9L 4ZBRA 3KIKA 5HOZA 4NAWB 2XVVA 4F5TA 1E7FA 2DG5A 2QM6A 5BPKA 4S1YA 4L8UA 4ZC6A 4IW1A 4GDXA 3LU6A 3V03A 4FJCB 5IIXA 4LB2A 3WHRA 1FOUA 2KBZA 2OT3A 5ID7A 1VFIA 4OTTA 5B5TA 3FWCC 2DBXA 3WHSA 4C31B 1BM0A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2I2Z A;  2BXE A;  3UIV A;  1HA2 A;  4K71 A;  5GHK A;  2VDB A;  3B9M A;  2BXF A;  4J2V A;  4G04 A;  5DQF A;  2I30 A;  1HK2 A;  3JRY A;  2BXL A;  4HGK A;  2BXM A;  1E7B A;  1E7C A;  2VUE A;  1E7I A;  2XSI A;  5FUO A;  2VUF A;  1E7H A;  5IJE A;  2XW1 A;  4BKE A;  1GNJ A;  4EMX A;  4JK4 A;  3V09 A;  4F5S A;  1AO6 A;  5IIU A;  1N5U A;  3A73 A;  3V08 A;  1HK4 A;  2BXC A;  4F5U A;  1HK5 A;  5ID9 A;  4N0U D;  4LUH A;  5IJF A;  5IIH A;  1MA9 A;  4LB9 A;  1J78 A;  1TF0 A;  1UOR A;  3LU7 A;  4PO0 A;  2BXA A;  2BXD A;  2BXH A;  4OR0 A;  3TDL A;  4LA0 A;  4L9Q A;  1HK1 A;  4LUF A;  1BKE A;  4HGM B;  5IFO A;  2BXQ A;  1HK3 A;  3CX9 A;  4E99 A;  4Z69 A;  1KW2 A;  5DBY A;  2BXP A;  1E7E A;  2XVU A;  2BXO A;  1GNI A;  2XW0 A;  1KXP D;  2BXN A;  2XVW A;  2BX8 A;  3B9L A;  4L9K A;  2BXK A;  2BXG A;  3SQJ A;  2BXI A;  3JQZ A;  1E7G A;  5IJ5 A;  4K2C A;  1O9X A;  4OT2 A;  2YDF A;  4F5V A;  2BXB A;  1LOT A;  4G03 A;  1E78 A;  1H9Z A;  2XVQ A;  4N0F D;  4ZBQ A;  1E7A A;  1J7E A;  1BJ5 A;  4IW2 A;  3LU8 A;  4ZBR A;  5HOZ A;  2XVV A;  4F5T A;  1E7F A;  4S1Y A;  4L8U A;  4IW1 A;  3LU6 A;  3V03 A;  5IIX A;  4LB2 A;  5ID7 A;  1BM0 A; 
#chains in the Genus database with same CATH topology
 2I2Z A;  4GDK B;  1H5W A;  2BXE A;  3UIV A;  1HA2 A;  1VZS A;  4K71 A;  5GHK A;  2VDB A;  3B9M A;  2JUH A;  3GQU A;  1LNS A;  2BXF A;  4DM0 A;  4I9O A;  4J2V A;  2DBU A;  4G04 A;  4W4U B;  2I30 A;  5DQF A;  1HK2 A;  2DYM A;  3JRY A;  1MM8 A;  2QMC A;  3SIV B;  2BXL A;  4ZBK A;  3SIU B;  2ROH A;  4HGK A;  3PLA A;  2AJE A;  1MIW A;  3M99 C;  2BXM A;  1E7B A;  1MUH A;  4ZCG A;  3NVI A;  1E7C A;  2VUE A;  1E7I A;  2XSI A;  5FUO A;  5GIP A;  3H37 A;  4GG2 A;  2VUF A;  1E7H A;  5IJE A;  2XW1 A;  4BKE A;  1GNJ A;  3FNM A;  4EMX A;  4JK4 A;  2NQO A;  3V09 A;  4F5S A;  4D7X A;  3H3A A;  4Z9O A;  1AO6 A;  2AGH B;  2OZB B;  5IIU A;  1MIV A;  3NVK A;  1N5U A;  2CKX A;  3A73 A;  2E0X A;  3V08 A;  4N3Z A;  2GUT A;  1HK4 A;  2BXC A;  4F5U A;  2EFE A;  1HK5 A;  5ID9 A;  2EFH A;  4N0U D;  2QHB A;  4GDL B;  4DHX B;  4LUH A;  2XMO A;  5IIH A;  5IJF A;  1MA9 A;  3FWB C;  2Z8J A;  4LB9 A;  5D7G A;  1J78 A;  1TF0 A;  4OTU A;  1UOR A;  1NT2 B;  2EFC A;  3LU7 A;  2LQH A;  3MHS B;  4PO0 A;  1MIY A;  3W1S A;  3VQI A;  2BXA A;  4G01 A;  5GIO A;  2BXD A;  2BXH A;  4TQ0 A;  4TQ1 A;  5GIN A;  2DYO A;  4OR0 A;  3TDL A;  4LA0 A;  3G9K D;  4L9Q A;  1HK1 A;  4LUF A;  1BKE A;  4FIP B;  4HGM B;  2BXQ A;  1HK3 A;  5IFO A;  3CX9 A;  4E99 A;  4Z69 A;  1KW2 A;  2Z8K A;  3ICX A;  3WHQ A;  5DBY A;  4MBE C;  3NVM A;  2BXP A;  1E7E A;  2XVU A;  2LOQ A;  2BXO A;  1GNI A;  1JNB A;  2XW0 A;  2NNW A;  1KXP D;  2BXN A;  3ECP A;  1SB0 A;  2XVW A;  4BY9 C;  2BX8 A;  2V36 A;  4FK5 B;  1MUS A;  3B9L A;  4L9K A;  2BXK A;  2BXG A;  3SQJ A;  2BXI A;  3JQZ A;  1E7G A;  2LXT A;  5IJ5 A;  3GQX A;  3NMU A;  1TXU A;  4K2C A;  1O9X A;  4OT2 A;  4WA6 B;  2E0Y A;  2LXS A;  2YDF A;  3MHH B;  4ZUX V;  4F5V A;  2BXB A;  3KJL A;  1LOT A;  4G03 A;  1E78 A;  1H9Z A;  2KWF A;  1KDX A;  2XVQ A;  4N0F D;  2Z8I A;  3A75 A;  4M70 B;  1E7A A;  4ZBQ A;  2DBW A;  1J7E A;  1BJ5 A;  2EFD A;  4IW2 A;  1IJG A;  3LU8 A;  3GA9 L;  4ZBR A;  3KIK A;  5HOZ A;  4NAW B;  2XVV A;  4F5T A;  1E7F A;  2DG5 A;  2QM6 A;  3BPJ A;  4S1Y A;  5BPK A;  4L8U A;  4ZC6 A;  4IW1 A;  2LQI A;  4GDX A;  3LU6 A;  3V03 A;  4FJC B;  5IIX A;  4LB2 A;  3WHR A;  1FOU A;  2KBZ A;  2OT3 A;  5ID7 A;  1VFI A;  2K0N A;  4OTT A;  5B5T A;  3FWC C;  2DBX A;  3WHS A;  4C31 B;  1BM0 A; 
#chains in the Genus database with same CATH homology
 2I2Z A;  4GDK B;  1H5W A;  2BXE A;  3UIV A;  1HA2 A;  1VZS A;  4K71 A;  5GHK A;  2VDB A;  3B9M A;  2JUH A;  3GQU A;  1LNS A;  2BXF A;  4J2V A;  4W4U B;  2DBU A;  4G04 A;  5DQF A;  2I30 A;  1HK2 A;  2DYM A;  3JRY A;  3SIV B;  2QMC A;  2BXL A;  4ZBK A;  3SIU B;  2ROH A;  4HGK A;  3PLA A;  2AJE A;  1MIW A;  3M99 C;  2BXM A;  1E7B A;  4ZCG A;  3NVI A;  1E7C A;  2VUE A;  1E7I A;  2XSI A;  5FUO A;  5GIP A;  3H37 A;  4GG2 A;  2VUF A;  1E7H A;  5IJE A;  2XW1 A;  4BKE A;  1GNJ A;  3FNM A;  4EMX A;  4JK4 A;  2NQO A;  3V09 A;  4F5S A;  3H3A A;  4Z9O A;  1AO6 A;  2OZB B;  5IIU A;  1MIV A;  3NVK A;  1N5U A;  2CKX A;  3A73 A;  2E0X A;  3V08 A;  4N3Z A;  1HK4 A;  2BXC A;  4F5U A;  2EFE A;  1HK5 A;  5ID9 A;  2EFH A;  4N0U D;  2QHB A;  4GDL B;  4DHX B;  4LUH A;  2XMO A;  5IIH A;  5IJF A;  1MA9 A;  3FWB C;  2Z8J A;  4LB9 A;  5D7G A;  1J78 A;  1TF0 A;  4OTU A;  1UOR A;  1NT2 B;  2EFC A;  3LU7 A;  3MHS B;  4PO0 A;  1MIY A;  3W1S A;  3VQI A;  2BXA A;  4G01 A;  5GIO A;  2BXD A;  2BXH A;  4TQ0 A;  4TQ1 A;  5GIN A;  2DYO A;  4OR0 A;  3TDL A;  4LA0 A;  3G9K D;  4L9Q A;  1HK1 A;  4LUF A;  1BKE A;  4FIP B;  4HGM B;  2BXQ A;  1HK3 A;  5IFO A;  3CX9 A;  4E99 A;  4Z69 A;  1KW2 A;  2Z8K A;  3ICX A;  3WHQ A;  5DBY A;  4MBE C;  3NVM A;  2BXP A;  1E7E A;  2XVU A;  2LOQ A;  2BXO A;  1GNI A;  1JNB A;  2XW0 A;  2NNW A;  1KXP D;  2BXN A;  2XVW A;  4BY9 C;  2BX8 A;  2V36 A;  4FK5 B;  3B9L A;  4L9K A;  2BXK A;  2BXG A;  3SQJ A;  2BXI A;  3JQZ A;  1E7G A;  3NMU A;  5IJ5 A;  3GQX A;  1TXU A;  4K2C A;  1O9X A;  4OT2 A;  4WA6 B;  2E0Y A;  2YDF A;  3MHH B;  4ZUX V;  4F5V A;  2BXB A;  3KJL A;  1LOT A;  4G03 A;  1E78 A;  1H9Z A;  2XVQ A;  4N0F D;  2Z8I A;  3A75 A;  4M70 B;  1E7A A;  4ZBQ A;  2DBW A;  1J7E A;  1BJ5 A;  2EFD A;  4IW2 A;  1IJG A;  3LU8 A;  3GA9 L;  4ZBR A;  3KIK A;  5HOZ A;  4NAW B;  2XVV A;  4F5T A;  1E7F A;  2DG5 A;  2QM6 A;  5BPK A;  4S1Y A;  4L8U A;  4ZC6 A;  4IW1 A;  4GDX A;  3LU6 A;  3V03 A;  4FJC B;  5IIX A;  4LB2 A;  3WHR A;  1FOU A;  2KBZ A;  2OT3 A;  5ID7 A;  1VFI A;  4OTT A;  5B5T A;  3FWC C;  2DBX A;  3WHS A;  4C31 B;  1BM0 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2BXMA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations