2BXO | Genus

Total Genus 228

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	228
sequence length	582
structure length	582
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transport protein
source organism	Homo sapiens
publication title	Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	228
structure length	582
sequence length	582
ec nomenclature
pdb deposition date	2005-07-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxoA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxoA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxoA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxoA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxoA06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	2bxoA05

1BM0A 1E78A 2XW0A 5GHKA 4LA0A 2VUEA 4LB2A 2XSIA 1MA9A 3UIVA 5IJEA 3V03A 5IJ5A 2BXNA 1J7EA 4G04A 4BKEA 2BXBA 4N0UD 4G03A 4K2CA 1N5UA 2I30A 2BXEA 2BXGA 4JK4A 4LUFA 3JRYA 5IIUA 4IW1A 4K71A 1KW2A 3A73A 5DQFA 2BXKA 5ID9A 1AO6A 4F5TA 3V09A 5DBYA 2BXDA 2XVUA 1BKEA 3LU8A 1E7AA 2BXPA 2XW1A 4ZBRA 3SQJA 1UORA 4OR0A 2BXFA 4HGKA 4PO0A 5HOZA 5IJFA 1E7EA 4ZBQA 5FUOA 4F5SA 2VDBA 2BX8A 4Z69A 1KXPD 1H9ZA 1J78A 5IIXA 2BXLA 2BXIA 4LUHA 2I2ZA 1O9XA 4OT2A 4F5UA 1E7IA 2BXOA 1E7HA 2BXAA 4LB9A 1E7BA 2BXMA 2XVVA 2VUFA 1HK2A 2XVQA 1GNIA 4L9QA 4L8UA 4E99A 4S1YA 1LOTA 3B9MA 1E7GA 4L9KA 4EMXA 1HK1A 3V08A 4N0FD 2BXCA 1BJ5A 4F5VA 4IW2A 3JQZA 2YDFA 4J2VA 1HK4A 3LU6A 5IFOA 1E7CA 1HA2A 2BXQA 1HK3A 3B9LA 5IIHA 3TDLA 2BXHA 3LU7A 1TF0A 1HK5A 2XVWA 4HGMB 5ID7A 1E7FA 1GNJA 3CX9A
chains in the Genus database with same CATH superfamily

1BM0A 1E78A 4DM0A 2XW0A 2EFHA 5GHKA 4LA0A 4GDKB 2DYOA 2VUEA 4LB2A 5BPKA 3M99C 2XSIA 1MA9A 3UIVA 5IJEA 2LXSA 2V36A 3H3AA 1MM8A 3NVKA 3V03A 5IJ5A 3FNMA 4MBEC 2GUTA 1MIYA 2BXNA 1J7EA 4G04A 4BKEA 2BXBA 2LOQA 4GG2A 4N0UD 2CKXA 2AJEA 4G03A 1MIVA 4C31B 2E0XA 4K2CA 1N5UA 2I30A 2K0NA 2NQOA 2BXEA 2BXGA 2KWFA 4JK4A 2EFDA 1H5WA 4LUFA 3JRYA 5IIUA 4G01A 4IW1A 4K71A 1KW2A 3A73A 4NAWB 5DQFA 2BXKA 3KIKA 1MIWA 2EFCA 4ZC6A 5ID9A 1AO6A 2LQIA 1LNSA 4F5TA 3V09A 4FJCB 4TQ1A 1KDXA 5DBYA 2BXDA 2XVUA 1BKEA 3LU8A 3GQUA 1E7AA 2LQHA 4ZUXV 1TXUA 2BXPA 2XW1A 4ZBRA 3WHRA 3SQJA 1UORA 1JNBA 4OR0A 2BXFA 4HGKA 4WA6B 4PO0A 2QHBA 5HOZA 5IJFA 1E7EA 4OTUA 4ZBQA 5FUOA 3GQXA 2ROHA 4D7XA 4F5SA 2DBXA 2OZBB 3H37A 2VDBA 3NVIA 3W1SA 3GA9L 2KBZA 2BX8A 4Z69A 3SIVB 1KXPD 4BY9C 3MHSB 2E0YA 4M70B 1H9ZA 2NNWA 1J78A 4TQ0A 2Z8JA 5IIXA 2BXLA 2AGHB 4Z9OA 2BXIA 4LUHA 2I2ZA 2LXTA 1O9XA 4OT2A 4F5UA 1E7IA 3ECPA 4N3ZA 3WHQA 2DYMA 2BXOA 4DHXB 5GIPA 1E7HA 2BXAA 4LB9A 1E7BA 2BXMA 2XVVA 2VUFA 1HK2A 1VZSA 4ZBKA 1NT2B 3VQIA 2XVQA 1GNIA 4L9QA 4W4UB 4L8UA 4FK5B 4E99A 3A75A 4GDXA 4S1YA 1LOTA 5B5TA 3B9MA 3BPJA 1E7GA 3ICXA 5GIOA 4L9KA 4EMXA 1HK1A 4OTTA 3FWCC 3V08A 4I9OA 4N0FD 1MUHA 2BXCA 3NMUA 5GINA 1FOUA 2DBWA 3G9KD 1BJ5A 4F5VA 1SB0A 4IW2A 1MUSA 3KJLA 2Z8IA 3JQZA 2YDFA 3SIUB 4J2VA 1HK4A 3LU6A 5IFOA 1E7CA 1HA2A 2BXQA 2XMOA 1HK3A 3B9LA 5IIHA 3TDLA 2Z8KA 3PLAA 2DG5A 2BXHA 2DBUA 3LU7A 5D7GA 3WHSA 1TF0A 1HK5A 2JUHA 2QMCA 2XVWA 2QM6A 4HGMB 1IJGA 3MHHB 4ZCGA 5ID7A 3NVMA 1E7FA 1VFIA 1GNJA 3FWBC 3CX9A 4GDLB 2OT3A 2EFEA 4FIPB
chains in the Genus database with same CATH topology

1BM0A 1E78A 2XW0A 2EFHA 5GHKA 4LA0A 4GDKB 2DYOA 2VUEA 4LB2A 5BPKA 3M99C 2XSIA 1MA9A 3UIVA 5IJEA 2V36A 3H3AA 3NVKA 3V03A 5IJ5A 3FNMA 4MBEC 1MIYA 2BXNA 1J7EA 4G04A 4BKEA 2BXBA 2LOQA 4GG2A 4N0UD 2CKXA 2AJEA 4G03A 1MIVA 4C31B 2E0XA 4K2CA 1N5UA 2I30A 2NQOA 2BXEA 2BXGA 4JK4A 4LUFA 2EFDA 1H5WA 3JRYA 5IIUA 4G01A 4IW1A 4K71A 1KW2A 3A73A 4NAWB 5DQFA 2BXKA 3KIKA 1MIWA 2EFCA 4ZC6A 5ID9A 1AO6A 1LNSA 4F5TA 3V09A 4FJCB 4TQ1A 5DBYA 2BXDA 2XVUA 1BKEA 3LU8A 3GQUA 1E7AA 4ZUXV 1TXUA 2BXPA 2XW1A 4ZBRA 3WHRA 3SQJA 1UORA 1JNBA 4OR0A 2BXFA 4HGKA 4WA6B 4PO0A 2QHBA 5HOZA 5IJFA 1E7EA 4OTUA 4ZBQA 5FUOA 3GQXA 2ROHA 4F5SA 2DBXA 2OZBB 3H37A 2VDBA 3NVIA 3W1SA 3GA9L 2KBZA 2BX8A 4Z69A 3SIVB 1KXPD 4BY9C 3MHSB 2E0YA 4M70B 1H9ZA 2NNWA 1J78A 4TQ0A 2Z8JA 5IIXA 2BXLA 4Z9OA 2BXIA 4LUHA 2I2ZA 1O9XA 4OT2A 4F5UA 1E7IA 4N3ZA 3WHQA 2DYMA 2BXOA 4DHXB 5GIPA 1E7HA 2BXAA 4LB9A 1E7BA 2BXMA 2XVVA 2VUFA 1HK2A 1VZSA 4ZBKA 1NT2B 3VQIA 2XVQA 1GNIA 4L9QA 4W4UB 4L8UA 4FK5B 4E99A 3A75A 4GDXA 4S1YA 1LOTA 5B5TA 3B9MA 5GIOA 1E7GA 3ICXA 4L9KA 4EMXA 1HK1A 4OTTA 3FWCC 3V08A 4N0FD 2BXCA 3NMUA 5GINA 1FOUA 2DBWA 3G9KD 1BJ5A 4F5VA 4IW2A 3KJLA 2Z8IA 3JQZA 2YDFA 3SIUB 4J2VA 1HK4A 3LU6A 5IFOA 1E7CA 1HA2A 2BXQA 2XMOA 1HK3A 3B9LA 5IIHA 3TDLA 2Z8KA 3PLAA 2DG5A 2BXHA 2DBUA 3LU7A 5D7GA 3WHSA 1TF0A 1HK5A 2JUHA 2QMCA 2XVWA 2QM6A 4HGMB 1IJGA 3MHHB 4ZCGA 5ID7A 3NVMA 1E7FA 1VFIA 1GNJA 3FWBC 3CX9A 4GDLB 2OT3A 2EFEA 4FIPB
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1BM0 A;  1E78 A;  2XW0 A;  5GHK A;  4LA0 A;  2VUE A;  4LB2 A;  2XSI A;  1MA9 A;  3UIV A;  5IJE A;  3V03 A;  5IJ5 A;  2BXN A;  1J7E A;  4G04 A;  4BKE A;  2BXB A;  4N0U D;  4G03 A;  4K2C A;  1N5U A;  2I30 A;  2BXE A;  2BXG A;  4JK4 A;  4LUF A;  3JRY A;  5IIU A;  4IW1 A;  4K71 A;  1KW2 A;  3A73 A;  5DQF A;  2BXK A;  5ID9 A;  1AO6 A;  4F5T A;  3V09 A;  5DBY A;  2BXD A;  2XVU A;  1BKE A;  3LU8 A;  1E7A A;  2BXP A;  2XW1 A;  4ZBR A;  3SQJ A;  1UOR A;  4OR0 A;  2BXF A;  4HGK A;  4PO0 A;  5HOZ A;  5IJF A;  1E7E A;  4ZBQ A;  5FUO A;  4F5S A;  2VDB A;  2BX8 A;  4Z69 A;  1KXP D;  1H9Z A;  1J78 A;  5IIX A;  2BXL A;  2BXI A;  4LUH A;  2I2Z A;  1O9X A;  4OT2 A;  4F5U A;  1E7I A;  2BXO A;  1E7H A;  2BXA A;  4LB9 A;  1E7B A;  2BXM A;  2XVV A;  2VUF A;  1HK2 A;  2XVQ A;  1GNI A;  4L9Q A;  4L8U A;  4E99 A;  4S1Y A;  1LOT A;  3B9M A;  1E7G A;  4L9K A;  4EMX A;  1HK1 A;  3V08 A;  4N0F D;  2BXC A;  1BJ5 A;  4F5V A;  4IW2 A;  3JQZ A;  2YDF A;  4J2V A;  1HK4 A;  3LU6 A;  5IFO A;  1E7C A;  1HA2 A;  2BXQ A;  1HK3 A;  3B9L A;  5IIH A;  3TDL A;  2BXH A;  3LU7 A;  1TF0 A;  1HK5 A;  2XVW A;  4HGM B;  5ID7 A;  1E7F A;  1GNJ A;  3CX9 A; 
#chains in the Genus database with same CATH topology
 1BM0 A;  1E78 A;  4DM0 A;  2XW0 A;  2EFH A;  5GHK A;  4LA0 A;  4GDK B;  2DYO A;  2VUE A;  4LB2 A;  5BPK A;  3M99 C;  2XSI A;  1MA9 A;  3UIV A;  5IJE A;  2LXS A;  2V36 A;  3H3A A;  1MM8 A;  3NVK A;  3V03 A;  5IJ5 A;  3FNM A;  4MBE C;  2GUT A;  1MIY A;  2BXN A;  1J7E A;  4G04 A;  4BKE A;  2BXB A;  2LOQ A;  4GG2 A;  4N0U D;  2CKX A;  2AJE A;  4G03 A;  1MIV A;  4C31 B;  2E0X A;  4K2C A;  1N5U A;  2I30 A;  2K0N A;  2NQO A;  2BXE A;  2BXG A;  2KWF A;  4JK4 A;  2EFD A;  1H5W A;  4LUF A;  3JRY A;  5IIU A;  4G01 A;  4IW1 A;  4K71 A;  1KW2 A;  3A73 A;  4NAW B;  5DQF A;  2BXK A;  3KIK A;  1MIW A;  2EFC A;  4ZC6 A;  5ID9 A;  1AO6 A;  2LQI A;  1LNS A;  4F5T A;  3V09 A;  4FJC B;  4TQ1 A;  1KDX A;  5DBY A;  2BXD A;  2XVU A;  1BKE A;  3LU8 A;  3GQU A;  1E7A A;  2LQH A;  4ZUX V;  1TXU A;  2BXP A;  2XW1 A;  4ZBR A;  3WHR A;  3SQJ A;  1UOR A;  1JNB A;  4OR0 A;  2BXF A;  4HGK A;  4WA6 B;  4PO0 A;  2QHB A;  5HOZ A;  5IJF A;  1E7E A;  4OTU A;  4ZBQ A;  5FUO A;  3GQX A;  2ROH A;  4D7X A;  4F5S A;  2DBX A;  2OZB B;  3H37 A;  2VDB A;  3NVI A;  3W1S A;  3GA9 L;  2KBZ A;  2BX8 A;  4Z69 A;  3SIV B;  1KXP D;  4BY9 C;  3MHS B;  2E0Y A;  4M70 B;  1H9Z A;  2NNW A;  1J78 A;  4TQ0 A;  2Z8J A;  5IIX A;  2BXL A;  2AGH B;  4Z9O A;  2BXI A;  4LUH A;  2I2Z A;  2LXT A;  1O9X A;  4OT2 A;  4F5U A;  1E7I A;  3ECP A;  4N3Z A;  3WHQ A;  2DYM A;  2BXO A;  4DHX B;  5GIP A;  1E7H A;  2BXA A;  4LB9 A;  1E7B A;  2BXM A;  2XVV A;  2VUF A;  1HK2 A;  1VZS A;  4ZBK A;  1NT2 B;  3VQI A;  2XVQ A;  1GNI A;  4L9Q A;  4W4U B;  4L8U A;  4FK5 B;  4E99 A;  3A75 A;  4GDX A;  4S1Y A;  1LOT A;  5B5T A;  3B9M A;  3BPJ A;  1E7G A;  3ICX A;  5GIO A;  4L9K A;  4EMX A;  1HK1 A;  4OTT A;  3FWC C;  3V08 A;  4I9O A;  4N0F D;  1MUH A;  2BXC A;  3NMU A;  5GIN A;  1FOU A;  2DBW A;  3G9K D;  1BJ5 A;  4F5V A;  1SB0 A;  4IW2 A;  1MUS A;  3KJL A;  2Z8I A;  3JQZ A;  2YDF A;  3SIU B;  4J2V A;  1HK4 A;  3LU6 A;  5IFO A;  1E7C A;  1HA2 A;  2BXQ A;  2XMO A;  1HK3 A;  3B9L A;  5IIH A;  3TDL A;  2Z8K A;  3PLA A;  2DG5 A;  2BXH A;  2DBU A;  3LU7 A;  5D7G A;  3WHS A;  1TF0 A;  1HK5 A;  2JUH A;  2QMC A;  2XVW A;  2QM6 A;  4HGM B;  1IJG A;  3MHH B;  4ZCG A;  5ID7 A;  3NVM A;  1E7F A;  1VFI A;  1GNJ A;  3FWB C;  3CX9 A;  4GDL B;  2OT3 A;  2EFE A;  4FIP B; 
#chains in the Genus database with same CATH homology
 1BM0 A;  1E78 A;  2XW0 A;  2EFH A;  5GHK A;  4LA0 A;  4GDK B;  2DYO A;  2VUE A;  4LB2 A;  5BPK A;  3M99 C;  2XSI A;  1MA9 A;  3UIV A;  5IJE A;  2V36 A;  3H3A A;  3NVK A;  3V03 A;  5IJ5 A;  3FNM A;  4MBE C;  1MIY A;  2BXN A;  1J7E A;  4G04 A;  4BKE A;  2BXB A;  2LOQ A;  4GG2 A;  4N0U D;  2CKX A;  2AJE A;  4G03 A;  1MIV A;  4C31 B;  2E0X A;  4K2C A;  1N5U A;  2I30 A;  2NQO A;  2BXE A;  2BXG A;  4JK4 A;  4LUF A;  2EFD A;  1H5W A;  3JRY A;  5IIU A;  4G01 A;  4IW1 A;  4K71 A;  1KW2 A;  3A73 A;  4NAW B;  5DQF A;  2BXK A;  3KIK A;  1MIW A;  2EFC A;  4ZC6 A;  5ID9 A;  1AO6 A;  1LNS A;  4F5T A;  3V09 A;  4FJC B;  4TQ1 A;  5DBY A;  2BXD A;  2XVU A;  1BKE A;  3LU8 A;  3GQU A;  1E7A A;  4ZUX V;  1TXU A;  2BXP A;  2XW1 A;  4ZBR A;  3WHR A;  3SQJ A;  1UOR A;  1JNB A;  4OR0 A;  2BXF A;  4HGK A;  4WA6 B;  4PO0 A;  2QHB A;  5HOZ A;  5IJF A;  1E7E A;  4OTU A;  4ZBQ A;  5FUO A;  3GQX A;  2ROH A;  4F5S A;  2DBX A;  2OZB B;  3H37 A;  2VDB A;  3NVI A;  3W1S A;  3GA9 L;  2KBZ A;  2BX8 A;  4Z69 A;  3SIV B;  1KXP D;  4BY9 C;  3MHS B;  2E0Y A;  4M70 B;  1H9Z A;  2NNW A;  1J78 A;  4TQ0 A;  2Z8J A;  5IIX A;  2BXL A;  4Z9O A;  2BXI A;  4LUH A;  2I2Z A;  1O9X A;  4OT2 A;  4F5U A;  1E7I A;  4N3Z A;  3WHQ A;  2DYM A;  2BXO A;  4DHX B;  5GIP A;  1E7H A;  2BXA A;  4LB9 A;  1E7B A;  2BXM A;  2XVV A;  2VUF A;  1HK2 A;  1VZS A;  4ZBK A;  1NT2 B;  3VQI A;  2XVQ A;  1GNI A;  4L9Q A;  4W4U B;  4L8U A;  4FK5 B;  4E99 A;  3A75 A;  4GDX A;  4S1Y A;  1LOT A;  5B5T A;  3B9M A;  5GIO A;  1E7G A;  3ICX A;  4L9K A;  4EMX A;  1HK1 A;  4OTT A;  3FWC C;  3V08 A;  4N0F D;  2BXC A;  3NMU A;  5GIN A;  1FOU A;  2DBW A;  3G9K D;  1BJ5 A;  4F5V A;  4IW2 A;  3KJL A;  2Z8I A;  3JQZ A;  2YDF A;  3SIU B;  4J2V A;  1HK4 A;  3LU6 A;  5IFO A;  1E7C A;  1HA2 A;  2BXQ A;  2XMO A;  1HK3 A;  3B9L A;  5IIH A;  3TDL A;  2Z8K A;  3PLA A;  2DG5 A;  2BXH A;  2DBU A;  3LU7 A;  5D7G A;  3WHS A;  1TF0 A;  1HK5 A;  2JUH A;  2QMC A;  2XVW A;  2QM6 A;  4HGM B;  1IJG A;  3MHH B;  4ZCG A;  5ID7 A;  3NVM A;  1E7F A;  1VFI A;  1GNJ A;  3FWB C;  3CX9 A;  4GDL B;  2OT3 A;  2EFE A;  4FIP B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2BXOA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations