2I2ZA

Human serum albumin complexed with myristate and aspirin
Total Genus 220
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
220
sequence length
582
structure length
581
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lipid binding protein
publication title Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin
pubmed doi rcsb
molecule keywords Serum albumin
total genus 220
structure length 581
sequence length 582
ec nomenclature
pdb deposition date 2006-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i2zA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i2zA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i2zA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i2zA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i2zA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2i2zA05
2BXLA 5IJ5A 2YDFA 2BX8A 1UORA 4EMXA 5IJFA 1HK3A 3CX9A 4N0UD 4Z69A 4L9KA 2XVUA 4OR0A 4LA0A 1LOTA 3B9LA 2BXEA 4ZBQA 4HGMB 4K71A 1HK4A 1H9ZA 4F5TA 1KW2A 1E7HA 2BXHA 4PO0A 2VDBA 4F5SA 5IIHA 2XVWA 2XSIA 1J78A 1BJ5A 2BXBA 3V08A 3JQZA 1E7EA 2VUFA 1GNJA 2BXNA 2BXQA 5DQFA 3LU7A 1E7CA 4G03A 2BXIA 1J7EA 1AO6A 1MA9A 1HK5A 3UIVA 1O9XA 4F5UA 4JK4A 4S1YA 2I30A 5IIUA 2BXKA 4LUHA 4J2VA 1E7AA 5HOZA 2XVVA 1HK1A 2BXCA 1TF0A 1BM0A 5IFOA 1E7GA 4ZBRA 1E7FA 5GHKA 1HK2A 4LB2A 3JRYA 4E99A 3A73A 1KXPD 3LU6A 3SQJA 1E78A 3V03A 5IJEA 2BXDA 2BXAA 3LU8A 4F5VA 2BXGA 4LB9A 2BXMA 2XVQA 5ID9A 2BXOA 5DBYA 4IW2A 1HA2A 5FUOA 4G04A 3TDLA 1N5UA 4L9QA 3V09A 4K2CA 4L8UA 1E7BA 2I2ZA 1E7IA 3B9MA 5ID7A 4BKEA 4IW1A 4HGKA 2XW1A 4N0FD 4LUFA 4OT2A 2VUEA 2BXFA 1GNIA 2XW0A 5IIXA 2BXPA 1BKEA
chains in the Genus database with same CATH superfamily
2BXLA 4DHXB 2CKXA 5IJ5A 2YDFA 2BX8A 2LQIA 4ZCGA 4DM0A 1UORA 2DBWA 1IJGA 1LNSA 2OT3A 3H3AA 4EMXA 1MIWA 5IJFA 1HK3A 3FNMA 4GDLB 3CX9A 4N0UD 1JNBA 1TXUA 4Z69A 4L9KA 5GIPA 2K0NA 2Z8IA 2DYOA 2XVUA 2LXTA 4OR0A 4LA0A 5BPKA 4C31B 1LOTA 3NVMA 5B5TA 3B9LA 2BXEA 4ZBQA 4HGMB 4K71A 3H37A 4TQ0A 3SIUB 1HK4A 1H9ZA 3WHSA 4F5TA 1KW2A 1E7HA 2BXHA 2E0YA 4PO0A 2DG5A 3NVKA 4ZBKA 2VDBA 2AJEA 4OTTA 4W4UB 3VQIA 4F5SA 1MUSA 3GA9L 4Z9OA 5IIHA 4TQ1A 2XVWA 2XSIA 1BJ5A 1J78A 1VFIA 2BXBA 2DYMA 2Z8JA 3V08A 2DBXA 3WHQA 3JQZA 1E7EA 2VUFA 1KDXA 1GNJA 2BXNA 2BXQA 2V36A 3BPJA 3ICXA 5DQFA 1H5WA 3LU7A 1NT2B 2XMOA 1E7CA 4G03A 4MBEC 3W1SA 2EFCA 2BXIA 4WA6B 1MM8A 3NMUA 1J7EA 4D7XA 1AO6A 3FWCC 4ZC6A 3FWBC 2ROHA 1MA9A 1HK5A 2NQOA 1O9XA 1VZSA 4I9OA 4M70B 4JK4A 3UIVA 4F5UA 4FIPB 3PLAA 4S1YA 2I30A 5IIUA 3NVIA 2BXKA 3SIVB 1MIYA 4LUHA 4J2VA 1E7AA 5HOZA 2XVVA 1HK1A 2BXCA 2QHBA 1TF0A 1BM0A 5IFOA 1E7GA 4ZBRA 1E7FA 5GHKA 1HK2A 4LB2A 3JRYA 4NAWB 1FOUA 2AGHB 4E99A 2GUTA 3GQXA 3A73A 3M99C 1KXPD 3LU6A 3KIKA 3SQJA 1E78A 2LOQA 3V03A 2NNWA 2E0XA 5IJEA 3WHRA 2BXDA 2BXAA 3LU8A 4F5VA 2EFHA 2BXGA 4LB9A 2Z8KA 2DBUA 3MHHB 2BXMA 4G01A 2LXSA 5D7GA 4ZUXV 3KJLA 2XVQA 5ID9A 2BXOA 5DBYA 4BY9C 4FK5B 3GQUA 4IW2A 1HA2A 5FUOA 5GIOA 1SB0A 2QMCA 1N5UA 2QM6A 4G04A 4GG2A 4L9QA 3TDLA 4K2CA 3V09A 4L8UA 2JUHA 2LQHA 3G9KD 2OZBB 2KBZA 1E7BA 2I2ZA 1E7IA 4OTUA 2KWFA 3B9MA 5ID7A 4BKEA 4IW1A 5GINA 4HGKA 3A75A 3MHSB 3ECPA 2EFDA 2XW1A 4FJCB 4GDXA 2EFEA 1MIVA 4LUFA 4N0FD 4OT2A 1MUHA 2VUEA 2BXFA 1GNIA 4GDKB 2XW0A 5IIXA 4N3ZA 2BXPA 1BKEA
chains in the Genus database with same CATH topology
2BXLA 4DHXB 2CKXA 5IJ5A 2YDFA 2BX8A 4ZCGA 1UORA 2DBWA 1IJGA 1LNSA 2OT3A 3H3AA 4EMXA 1MIWA 5IJFA 1HK3A 3FNMA 4GDLB 3CX9A 4N0UD 1JNBA 1TXUA 4Z69A 4L9KA 5GIPA 2Z8IA 2DYOA 2XVUA 4OR0A 5BPKA 4LA0A 4C31B 1LOTA 3NVMA 5B5TA 3B9LA 2BXEA 4ZBQA 4HGMB 4K71A 3H37A 4TQ0A 3SIUB 1HK4A 1H9ZA 3WHSA 4F5TA 1KW2A 1E7HA 2BXHA 2E0YA 4PO0A 2DG5A 4ZBKA 2VDBA 2AJEA 4OTTA 4W4UB 3VQIA 4F5SA 3GA9L 4Z9OA 5IIHA 4TQ1A 2XVWA 2XSIA 1BJ5A 1J78A 1VFIA 2BXBA 2DYMA 2Z8JA 3V08A 2DBXA 3WHQA 3JQZA 1E7EA 2VUFA 1GNJA 2BXNA 2BXQA 2V36A 3ICXA 5DQFA 1H5WA 3LU7A 1NT2B 2XMOA 1E7CA 4G03A 4MBEC 3W1SA 2EFCA 2BXIA 4WA6B 3NMUA 1J7EA 1AO6A 3FWCC 4ZC6A 3FWBC 2ROHA 1MA9A 1HK5A 2NQOA 1O9XA 1VZSA 4M70B 3UIVA 4JK4A 4F5UA 3NVIA 4FIPB 3PLAA 4S1YA 2I30A 5IIUA 2BXKA 3SIVB 1MIYA 4LUHA 4J2VA 1E7AA 5HOZA 2XVVA 1HK1A 2BXCA 2QHBA 1TF0A 1BM0A 5IFOA 1E7GA 4ZBRA 1E7FA 5GHKA 1HK2A 4LB2A 3JRYA 4NAWB 1FOUA 4E99A 3GQXA 3A73A 3M99C 1KXPD 3LU6A 3KIKA 3SQJA 1E78A 2LOQA 3V03A 2NNWA 2E0XA 5IJEA 3WHRA 2BXDA 2BXAA 3LU8A 4F5VA 2EFHA 2BXGA 4LB9A 2Z8KA 2DBUA 3MHHB 2BXMA 4G01A 5D7GA 4ZUXV 3KJLA 2XVQA 5ID9A 2BXOA 5DBYA 4BY9C 4FK5B 3GQUA 4IW2A 1HA2A 5FUOA 5GIOA 2QMCA 4G04A 1N5UA 2QM6A 4GG2A 4L9QA 3TDLA 3V09A 4K2CA 3NVKA 4L8UA 2JUHA 3G9KD 2OZBB 2KBZA 1E7BA 2I2ZA 1E7IA 4OTUA 3B9MA 5ID7A 4BKEA 4IW1A 5GINA 4HGKA 3A75A 3MHSB 2EFDA 2XW1A 4FJCB 4GDXA 2EFEA 1MIVA 4LUFA 4N0FD 4OT2A 2VUEA 2BXFA 1GNIA 4GDKB 2XW0A 5IIXA 4N3ZA 2BXPA 1BKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXL A;  5IJ5 A;  2YDF A;  2BX8 A;  1UOR A;  4EMX A;  5IJF A;  1HK3 A;  3CX9 A;  4N0U D;  4Z69 A;  4L9K A;  2XVU A;  4OR0 A;  4LA0 A;  1LOT A;  3B9L A;  2BXE A;  4ZBQ A;  4HGM B;  4K71 A;  1HK4 A;  1H9Z A;  4F5T A;  1KW2 A;  1E7H A;  2BXH A;  4PO0 A;  2VDB A;  4F5S A;  5IIH A;  2XVW A;  2XSI A;  1J78 A;  1BJ5 A;  2BXB A;  3V08 A;  3JQZ A;  1E7E A;  2VUF A;  1GNJ A;  2BXN A;  2BXQ A;  5DQF A;  3LU7 A;  1E7C A;  4G03 A;  2BXI A;  1J7E A;  1AO6 A;  1MA9 A;  1HK5 A;  3UIV A;  1O9X A;  4F5U A;  4JK4 A;  4S1Y A;  2I30 A;  5IIU A;  2BXK A;  4LUH A;  4J2V A;  1E7A A;  5HOZ A;  2XVV A;  1HK1 A;  2BXC A;  1TF0 A;  1BM0 A;  5IFO A;  1E7G A;  4ZBR A;  1E7F A;  5GHK A;  1HK2 A;  4LB2 A;  3JRY A;  4E99 A;  3A73 A;  1KXP D;  3LU6 A;  3SQJ A;  1E78 A;  3V03 A;  5IJE A;  2BXD A;  2BXA A;  3LU8 A;  4F5V A;  2BXG A;  4LB9 A;  2BXM A;  2XVQ A;  5ID9 A;  2BXO A;  5DBY A;  4IW2 A;  1HA2 A;  5FUO A;  4G04 A;  3TDL A;  1N5U A;  4L9Q A;  3V09 A;  4K2C A;  4L8U A;  1E7B A;  2I2Z A;  1E7I A;  3B9M A;  5ID7 A;  4BKE A;  4IW1 A;  4HGK A;  2XW1 A;  4N0F D;  4LUF A;  4OT2 A;  2VUE A;  2BXF A;  1GNI A;  2XW0 A;  5IIX A;  2BXP A;  1BKE A; 
#chains in the Genus database with same CATH topology
 2BXL A;  4DHX B;  2CKX A;  5IJ5 A;  2YDF A;  2BX8 A;  2LQI A;  4ZCG A;  4DM0 A;  1UOR A;  2DBW A;  1IJG A;  1LNS A;  2OT3 A;  3H3A A;  4EMX A;  1MIW A;  5IJF A;  1HK3 A;  3FNM A;  4GDL B;  3CX9 A;  4N0U D;  1JNB A;  1TXU A;  4Z69 A;  4L9K A;  5GIP A;  2K0N A;  2Z8I A;  2DYO A;  2XVU A;  2LXT A;  4OR0 A;  4LA0 A;  5BPK A;  4C31 B;  1LOT A;  3NVM A;  5B5T A;  3B9L A;  2BXE A;  4ZBQ A;  4HGM B;  4K71 A;  3H37 A;  4TQ0 A;  3SIU B;  1HK4 A;  1H9Z A;  3WHS A;  4F5T A;  1KW2 A;  1E7H A;  2BXH A;  2E0Y A;  4PO0 A;  2DG5 A;  3NVK A;  4ZBK A;  2VDB A;  2AJE A;  4OTT A;  4W4U B;  3VQI A;  4F5S A;  1MUS A;  3GA9 L;  4Z9O A;  5IIH A;  4TQ1 A;  2XVW A;  2XSI A;  1BJ5 A;  1J78 A;  1VFI A;  2BXB A;  2DYM A;  2Z8J A;  3V08 A;  2DBX A;  3WHQ A;  3JQZ A;  1E7E A;  2VUF A;  1KDX A;  1GNJ A;  2BXN A;  2BXQ A;  2V36 A;  3BPJ A;  3ICX A;  5DQF A;  1H5W A;  3LU7 A;  1NT2 B;  2XMO A;  1E7C A;  4G03 A;  4MBE C;  3W1S A;  2EFC A;  2BXI A;  4WA6 B;  1MM8 A;  3NMU A;  1J7E A;  4D7X A;  1AO6 A;  3FWC C;  4ZC6 A;  3FWB C;  2ROH A;  1MA9 A;  1HK5 A;  2NQO A;  1O9X A;  1VZS A;  4I9O A;  4M70 B;  4JK4 A;  3UIV A;  4F5U A;  4FIP B;  3PLA A;  4S1Y A;  2I30 A;  5IIU A;  3NVI A;  2BXK A;  3SIV B;  1MIY A;  4LUH A;  4J2V A;  1E7A A;  5HOZ A;  2XVV A;  1HK1 A;  2BXC A;  2QHB A;  1TF0 A;  1BM0 A;  5IFO A;  1E7G A;  4ZBR A;  1E7F A;  5GHK A;  1HK2 A;  4LB2 A;  3JRY A;  4NAW B;  1FOU A;  2AGH B;  4E99 A;  2GUT A;  3GQX A;  3A73 A;  3M99 C;  1KXP D;  3LU6 A;  3KIK A;  3SQJ A;  1E78 A;  2LOQ A;  3V03 A;  2NNW A;  2E0X A;  5IJE A;  3WHR A;  2BXD A;  2BXA A;  3LU8 A;  4F5V A;  2EFH A;  2BXG A;  4LB9 A;  2Z8K A;  2DBU A;  3MHH B;  2BXM A;  4G01 A;  2LXS A;  5D7G A;  4ZUX V;  3KJL A;  2XVQ A;  5ID9 A;  2BXO A;  5DBY A;  4BY9 C;  4FK5 B;  3GQU A;  4IW2 A;  1HA2 A;  5FUO A;  5GIO A;  1SB0 A;  2QMC A;  1N5U A;  2QM6 A;  4G04 A;  4GG2 A;  4L9Q A;  3TDL A;  4K2C A;  3V09 A;  4L8U A;  2JUH A;  2LQH A;  3G9K D;  2OZB B;  2KBZ A;  1E7B A;  2I2Z A;  1E7I A;  4OTU A;  2KWF A;  3B9M A;  5ID7 A;  4BKE A;  4IW1 A;  5GIN A;  4HGK A;  3A75 A;  3MHS B;  3ECP A;  2EFD A;  2XW1 A;  4FJC B;  4GDX A;  2EFE A;  1MIV A;  4LUF A;  4N0F D;  4OT2 A;  1MUH A;  2VUE A;  2BXF A;  1GNI A;  4GDK B;  2XW0 A;  5IIX A;  4N3Z A;  2BXP A;  1BKE A; 
#chains in the Genus database with same CATH homology
 2BXL A;  4DHX B;  2CKX A;  5IJ5 A;  2YDF A;  2BX8 A;  4ZCG A;  1UOR A;  2DBW A;  1IJG A;  1LNS A;  2OT3 A;  3H3A A;  4EMX A;  1MIW A;  5IJF A;  1HK3 A;  3FNM A;  4GDL B;  3CX9 A;  4N0U D;  1JNB A;  1TXU A;  4Z69 A;  4L9K A;  5GIP A;  2Z8I A;  2DYO A;  2XVU A;  4OR0 A;  5BPK A;  4LA0 A;  4C31 B;  1LOT A;  3NVM A;  5B5T A;  3B9L A;  2BXE A;  4ZBQ A;  4HGM B;  4K71 A;  3H37 A;  4TQ0 A;  3SIU B;  1HK4 A;  1H9Z A;  3WHS A;  4F5T A;  1KW2 A;  1E7H A;  2BXH A;  2E0Y A;  4PO0 A;  2DG5 A;  4ZBK A;  2VDB A;  2AJE A;  4OTT A;  4W4U B;  3VQI A;  4F5S A;  3GA9 L;  4Z9O A;  5IIH A;  4TQ1 A;  2XVW A;  2XSI A;  1BJ5 A;  1J78 A;  1VFI A;  2BXB A;  2DYM A;  2Z8J A;  3V08 A;  2DBX A;  3WHQ A;  3JQZ A;  1E7E A;  2VUF A;  1GNJ A;  2BXN A;  2BXQ A;  2V36 A;  3ICX A;  5DQF A;  1H5W A;  3LU7 A;  1NT2 B;  2XMO A;  1E7C A;  4G03 A;  4MBE C;  3W1S A;  2EFC A;  2BXI A;  4WA6 B;  3NMU A;  1J7E A;  1AO6 A;  3FWC C;  4ZC6 A;  3FWB C;  2ROH A;  1MA9 A;  1HK5 A;  2NQO A;  1O9X A;  1VZS A;  4M70 B;  3UIV A;  4JK4 A;  4F5U A;  3NVI A;  4FIP B;  3PLA A;  4S1Y A;  2I30 A;  5IIU A;  2BXK A;  3SIV B;  1MIY A;  4LUH A;  4J2V A;  1E7A A;  5HOZ A;  2XVV A;  1HK1 A;  2BXC A;  2QHB A;  1TF0 A;  1BM0 A;  5IFO A;  1E7G A;  4ZBR A;  1E7F A;  5GHK A;  1HK2 A;  4LB2 A;  3JRY A;  4NAW B;  1FOU A;  4E99 A;  3GQX A;  3A73 A;  3M99 C;  1KXP D;  3LU6 A;  3KIK A;  3SQJ A;  1E78 A;  2LOQ A;  3V03 A;  2NNW A;  2E0X A;  5IJE A;  3WHR A;  2BXD A;  2BXA A;  3LU8 A;  4F5V A;  2EFH A;  2BXG A;  4LB9 A;  2Z8K A;  2DBU A;  3MHH B;  2BXM A;  4G01 A;  5D7G A;  4ZUX V;  3KJL A;  2XVQ A;  5ID9 A;  2BXO A;  5DBY A;  4BY9 C;  4FK5 B;  3GQU A;  4IW2 A;  1HA2 A;  5FUO A;  5GIO A;  2QMC A;  4G04 A;  1N5U A;  2QM6 A;  4GG2 A;  4L9Q A;  3TDL A;  3V09 A;  4K2C A;  3NVK A;  4L8U A;  2JUH A;  3G9K D;  2OZB B;  2KBZ A;  1E7B A;  2I2Z A;  1E7I A;  4OTU A;  3B9M A;  5ID7 A;  4BKE A;  4IW1 A;  5GIN A;  4HGK A;  3A75 A;  3MHS B;  2EFD A;  2XW1 A;  4FJC B;  4GDX A;  2EFE A;  1MIV A;  4LUF A;  4N0F D;  4OT2 A;  2VUE A;  2BXF A;  1GNI A;  4GDK B;  2XW0 A;  5IIX A;  4N3Z A;  2BXP A;  1BKE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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