2LQIA

Nmr structure of foxo3a transactivation domains (cr2c-cr3) in complex with cbp kix domain (2l3b conformation)
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
87
structure length
87
Chain Sequence
GVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords CREB-binding protein
total genus 31
structure length 87
sequence length 87
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2012-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02172 KIX KIX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.20 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Coactivator CBP, KIX domain 2lqiA00
2GUTA 4I9OA 2LQIA 2AGHB 1KDXA 2K0NA 2LQHA 2LXSA 2LXTA 1SB0A 4D7XA 2KWFA
chains in the Genus database with same CATH superfamily
4K71A 2E0XA 5D7GA 4FK5B 2OT3A 4W4UB 2OZBB 1TF0A 4HGKA 4C31B 3KIKA 4G04A 1MA9A 2DBUA 1VZSA 3G9KD 1GNIA 2YDFA 5GINA 5GIOA 2QM6A 4ZCGA 3WHQA 4OTUA 3JRYA 3H3AA 4ZBRA 2I2ZA 3W1SA 2DYMA 2LQIA 1LOTA 2KBZA 4Z9OA 3ICXA 2XVWA 1BKEA 2ROHA 2V36A 3WHRA 5B5TA 2BXEA 3LU6A 1E7FA 4IW1A 2XVQA 2QHBA 3WHSA 4LUHA 4Z69A 2I30A 2BX8A 2XW1A 1TXUA 5BPKA 4IW2A 1MM8A 2BXGA 1HK4A 1NT2B 2BXFA 4F5VA 4DM0A 1HK5A 4ZBKA 5FUOA 1BM0A 2BXPA 1E7IA 4L9QA 4F5TA 3GQUA 4L9KA 4E99A 1N5UA 2BXNA 1H9ZA 2BXBA 2GUTA 3NVIA 1KW2A 1MUSA 3KJLA 1E7CA 5IIXA 3GQXA 2BXLA 1HK1A 3A75A 4D7XA 3LU8A 4LB2A 3VQIA 5ID7A 3LU7A 4BKEA 1HK2A 1E7HA 2DYOA 1E7EA 2BXAA 4GDLB 1AO6A 3SIVB 2XSIA 1E7GA 2NNWA 4ZBQA 2BXCA 2EFEA 3MHHB 1UORA 4PO0A 2CKXA 1GNJA 3ECPA 3GA9L 5IJFA 5GHKA 2BXQA 1HA2A 2BXKA 1E7AA 2BXIA 2LQHA 2NQOA 3NMUA 2KWFA 5IIHA 1MIWA 4N3ZA 5IIUA 3FWCC 3M99C 4GDKB 2XMOA 1VFIA 2VDBA 1O9XA 1KDXA 4N0FD 3SIUB 1HK3A 4F5UA 1MUHA 2XVVA 2AJEA 4TQ0A 4ZC6A 1MIVA 5DBYA 4G01A 4S1YA 3V09A 3NVMA 4LUFA 1H5WA 4TQ1A 4J2VA 3SQJA 2Z8JA 3V03A 2XVUA 2XW0A 4LB9A 2EFHA 3FNMA 4G03A 4FIPB 1KXPD 1IJGA 3H37A 3BPJA 3MHSB 1J7EA 1E7BA 2BXDA 3UIVA 2DBXA 4BY9C 2Z8KA 2K0NA 4WA6B 1FOUA 3B9MA 3JQZA 2BXHA 2JUHA 1MIYA 4FJCB 4OTTA 5IFOA 3B9LA 4M70B 4N0UD 2DBWA 2E0YA 4HGMB 5IJ5A 1BJ5A 4ZUXV 2DG5A 2VUEA 5HOZA 3TDLA 5ID9A 3PLAA 3A73A 3NVKA 4EMXA 2BXOA 1E78A 3V08A 4F5SA 4L8UA 4I9OA 1JNBA 5GIPA 4JK4A 4OT2A 4K2CA 4NAWB 2LOQA 2LXTA 2EFDA 4LA0A 4GG2A 5DQFA 4DHXB 2AGHB 4GDXA 4MBEC 2QMCA 4OR0A 2VUFA 3CX9A 3FWBC 2Z8IA 5IJEA 2BXMA 1LNSA 2EFCA 1J78A 2LXSA 1SB0A
chains in the Genus database with same CATH topology
2GUTA 4I9OA 2LQIA 2AGHB 1KDXA 2K0NA 2LQHA 2LXSA 2LXTA 1SB0A 4D7XA 2KWFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GUT A;  4I9O A;  2LQI A;  2AGH B;  1KDX A;  2K0N A;  2LQH A;  2LXS A;  2LXT A;  1SB0 A;  4D7X A;  2KWF A; 
#chains in the Genus database with same CATH topology
 4K71 A;  2E0X A;  5D7G A;  4FK5 B;  2OT3 A;  4W4U B;  2OZB B;  1TF0 A;  4HGK A;  4C31 B;  3KIK A;  4G04 A;  1MA9 A;  2DBU A;  1VZS A;  3G9K D;  1GNI A;  2YDF A;  5GIN A;  5GIO A;  2QM6 A;  4ZCG A;  3WHQ A;  4OTU A;  3JRY A;  3H3A A;  4ZBR A;  2I2Z A;  3W1S A;  2DYM A;  2LQI A;  1LOT A;  2KBZ A;  4Z9O A;  3ICX A;  2XVW A;  1BKE A;  2ROH A;  2V36 A;  3WHR A;  5B5T A;  2BXE A;  3LU6 A;  1E7F A;  4IW1 A;  2XVQ A;  2QHB A;  3WHS A;  4LUH A;  4Z69 A;  2I30 A;  2BX8 A;  2XW1 A;  1TXU A;  5BPK A;  4IW2 A;  1MM8 A;  2BXG A;  1HK4 A;  1NT2 B;  2BXF A;  4F5V A;  4DM0 A;  1HK5 A;  4ZBK A;  5FUO A;  1BM0 A;  2BXP A;  1E7I A;  4L9Q A;  4F5T A;  3GQU A;  4L9K A;  4E99 A;  1N5U A;  2BXN A;  1H9Z A;  2BXB A;  2GUT A;  3NVI A;  1KW2 A;  1MUS A;  3KJL A;  1E7C A;  5IIX A;  3GQX A;  2BXL A;  1HK1 A;  3A75 A;  4D7X A;  3LU8 A;  4LB2 A;  3VQI A;  5ID7 A;  3LU7 A;  4BKE A;  1HK2 A;  1E7H A;  2DYO A;  1E7E A;  2BXA A;  4GDL B;  1AO6 A;  3SIV B;  2XSI A;  1E7G A;  2NNW A;  4ZBQ A;  2BXC A;  2EFE A;  3MHH B;  1UOR A;  4PO0 A;  2CKX A;  1GNJ A;  3ECP A;  3GA9 L;  5IJF A;  5GHK A;  2BXQ A;  1HA2 A;  2BXK A;  1E7A A;  2BXI A;  2LQH A;  2NQO A;  3NMU A;  2KWF A;  5IIH A;  1MIW A;  4N3Z A;  5IIU A;  3FWC C;  3M99 C;  4GDK B;  2XMO A;  1VFI A;  2VDB A;  1O9X A;  1KDX A;  4N0F D;  3SIU B;  1HK3 A;  4F5U A;  1MUH A;  2XVV A;  2AJE A;  4TQ0 A;  4ZC6 A;  1MIV A;  5DBY A;  4G01 A;  4S1Y A;  3V09 A;  3NVM A;  4LUF A;  1H5W A;  4TQ1 A;  4J2V A;  3SQJ A;  2Z8J A;  3V03 A;  2XVU A;  2XW0 A;  4LB9 A;  2EFH A;  3FNM A;  4G03 A;  4FIP B;  1KXP D;  1IJG A;  3H37 A;  3BPJ A;  3MHS B;  1J7E A;  1E7B A;  2BXD A;  3UIV A;  2DBX A;  4BY9 C;  2Z8K A;  2K0N A;  4WA6 B;  1FOU A;  3B9M A;  3JQZ A;  2BXH A;  2JUH A;  1MIY A;  4FJC B;  4OTT A;  5IFO A;  3B9L A;  4M70 B;  4N0U D;  2DBW A;  2E0Y A;  4HGM B;  5IJ5 A;  1BJ5 A;  4ZUX V;  2DG5 A;  2VUE A;  5HOZ A;  3TDL A;  5ID9 A;  3PLA A;  3A73 A;  3NVK A;  4EMX A;  2BXO A;  1E78 A;  3V08 A;  4F5S A;  4L8U A;  4I9O A;  1JNB A;  5GIP A;  4JK4 A;  4OT2 A;  4K2C A;  4NAW B;  2LOQ A;  2LXT A;  2EFD A;  4LA0 A;  4GG2 A;  5DQF A;  4DHX B;  2AGH B;  4GDX A;  4MBE C;  2QMC A;  4OR0 A;  2VUF A;  3CX9 A;  3FWB C;  2Z8I A;  5IJE A;  2BXM A;  1LNS A;  2EFC A;  1J78 A;  2LXS A;  1SB0 A; 
#chains in the Genus database with same CATH homology
 2GUT A;  4I9O A;  2LQI A;  2AGH B;  1KDX A;  2K0N A;  2LQH A;  2LXS A;  2LXT A;  1SB0 A;  4D7X A;  2KWF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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