2VDBA

Structure of human serum albumin with s-naproxen and the ga module
Total Genus 203
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
203
sequence length
579
structure length
574
Chain Sequence
EVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for the Binding of Naproxen to Human Serum Albumin in the Presence of Fatty Acids and the Ga Module.
pubmed doi rcsb
molecule tags Protein binding
source organism Peptostreptococcus magnus
molecule keywords SERUM ALBUMIN
total genus 203
structure length 574
sequence length 579
ec nomenclature
pdb deposition date 2007-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2vdbA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2vdbA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2vdbA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2vdbA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2vdbA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2vdbA05
3LU8A 2XVUA 1HK2A 4PO0A 4Z69A 3B9MA 4ZBRA 5IIXA 4LB2A 1AO6A 1O9XA 1LOTA 1UORA 2BXGA 2BXIA 1E7EA 4N0UD 5FUOA 2BXCA 2BXHA 2I30A 4L8UA 3TDLA 5IJEA 2BXNA 2XVQA 2VUEA 1HK3A 1J78A 1E7GA 5IFOA 5IJFA 5DQFA 1TF0A 4J2VA 5HOZA 2BXMA 4L9QA 1E7BA 3B9LA 5DBYA 1E7CA 1HA2A 4HGMB 2BXLA 1GNJA 1HK5A 1MA9A 4HGKA 4G04A 1E7AA 4F5TA 2BXDA 5IJ5A 3V03A 2YDFA 1KXPD 4EMXA 5GHKA 2VDBA 2BXEA 1HK1A 1E7IA 4OR0A 2XVVA 4F5VA 1BM0A 5IIUA 4E99A 1BJ5A 3V08A 4LUHA 3LU7A 4G03A 4K2CA 2BX8A 1E78A 4OT2A 4N0FD 4IW1A 4LUFA 4IW2A 3UIVA 2BXPA 3JQZA 5IIHA 2XW1A 1E7FA 2I2ZA 4ZBQA 4F5UA 2BXQA 1GNIA 4K71A 2BXAA 4JK4A 5ID9A 1H9ZA 2BXOA 3CX9A 2XVWA 3LU6A 4F5SA 2XSIA 2XW0A 4BKEA 4L9KA 3JRYA 4S1YA 3SQJA 1KW2A 2VUFA 1J7EA 1E7HA 1N5UA 1BKEA 2BXBA 3V09A 2BXFA 4LB9A 2BXKA 4LA0A 5ID7A 1HK4A 3A73A
chains in the Genus database with same CATH superfamily
1NT2B 3LU8A 2XVUA 2QM6A 4ZCGA 2Z8IA 1HK2A 1FOUA 4PO0A 4Z69A 3B9MA 1SB0A 2EFCA 4ZBRA 5IIXA 4LB2A 4D7XA 4BY9C 1AO6A 1O9XA 1LOTA 1MIWA 1UORA 2BXGA 4TQ1A 2BXIA 1E7EA 4N0UD 2OT3A 5FUOA 2BXCA 2BXHA 2I30A 2E0YA 4L8UA 3TDLA 5GINA 1KDXA 4FK5B 5GIOA 3KJLA 4ZC6A 5IJEA 2LXSA 2XMOA 3NMUA 4GDKB 2BXNA 2V36A 3M99C 2XVQA 2VUEA 4DHXB 1HK3A 1J78A 1E7GA 2EFEA 2LQHA 5IFOA 5IJFA 5DQFA 1TF0A 4J2VA 2Z8KA 1VZSA 2BXMA 3G9KD 4L9QA 5HOZA 3SIUB 1E7BA 3B9LA 5DBYA 3SIVB 3NVIA 1E7CA 1MUSA 1HA2A 3WHRA 4HGMB 2BXLA 1GNJA 3ICXA 3BPJA 1HK5A 1MA9A 3FWCC 3VQIA 4Z9OA 4HGKA 4G04A 3WHSA 2DG5A 2DYOA 3MHHB 3A75A 2QMCA 1E7AA 4F5TA 2BXDA 2DYMA 4MBEC 4M70B 5BPKA 3MHSB 1MIYA 2EFHA 4FJCB 5IJ5A 3V03A 3GA9L 2NQOA 2YDFA 1KXPD 4GG2A 5GHKA 4EMXA 2OZBB 1MUHA 4FIPB 2LXTA 2VDBA 3GQXA 2BXEA 2K0NA 1HK1A 2ROHA 1E7IA 4C31B 3FNMA 4GDLB 2DBUA 2EFDA 2XVVA 4OR0A 4F5VA 1BM0A 1JNBA 5IIUA 2KWFA 4DM0A 3NVKA 4E99A 2LOQA 2DBXA 1BJ5A 3V08A 4LUHA 3LU7A 4G03A 4K2CA 2QHBA 1LNSA 2BX8A 1H5WA 4OTTA 2JUHA 1E78A 4OT2A 2AJEA 5B5TA 4N0FD 4IW1A 4GDXA 4ZUXV 4I9OA 4LUFA 4IW2A 3UIVA 3H3AA 2LQIA 2CKXA 4NAWB 2BXPA 4OTUA 3JQZA 5IIHA 2XW1A 1E7FA 2DBWA 2I2ZA 1IJGA 4ZBQA 2AGHB 4F5UA 3FWBC 2BXQA 1GNIA 3W1SA 3PLAA 4K71A 3H37A 5ID7A 2BXAA 4JK4A 1MIVA 4WA6B 5ID9A 2E0XA 3KIKA 1H9ZA 4ZBKA 2BXOA 3CX9A 3GQUA 2XVWA 3LU6A 4TQ0A 4G01A 2GUTA 4F5SA 2XSIA 2XW0A 3ECPA 1MM8A 5D7GA 2NNWA 1TXUA 4BKEA 4L9KA 3JRYA 4S1YA 3SQJA 1KW2A 2VUFA 1J7EA 3WHQA 1E7HA 1N5UA 1BKEA 2BXBA 2Z8JA 4N3ZA 3V09A 2BXFA 4LB9A 2BXKA 4LA0A 4W4UB 3NVMA 1VFIA 1HK4A 2KBZA 5GIPA 3A73A
chains in the Genus database with same CATH topology
1NT2B 3LU8A 2XVUA 2QM6A 4ZCGA 2Z8IA 1HK2A 1FOUA 4PO0A 4Z69A 3B9MA 2EFCA 4ZBRA 5IIXA 4LB2A 4BY9C 1AO6A 1O9XA 1LOTA 1MIWA 1UORA 2BXGA 4TQ1A 2BXIA 1E7EA 4N0UD 2OT3A 5FUOA 2BXCA 2BXHA 2I30A 2E0YA 4L8UA 3TDLA 5GINA 4FK5B 5GIOA 3KJLA 4ZC6A 5IJEA 2XMOA 3NMUA 4GDKB 2BXNA 2V36A 3M99C 2XVQA 2VUEA 4DHXB 1HK3A 1J78A 1E7GA 2EFEA 5IFOA 5IJFA 5DQFA 1TF0A 4J2VA 2Z8KA 1VZSA 2BXMA 3G9KD 4L9QA 5HOZA 3SIUB 1E7BA 3B9LA 5DBYA 3SIVB 3NVIA 1E7CA 1HA2A 3WHRA 4HGMB 2BXLA 1GNJA 3ICXA 1HK5A 1MA9A 3FWCC 3VQIA 4Z9OA 4HGKA 4G04A 3WHSA 2DG5A 2DYOA 3MHHB 3A75A 2QMCA 1E7AA 4F5TA 2BXDA 2DYMA 4MBEC 4M70B 5BPKA 3MHSB 1MIYA 2EFHA 4FJCB 5IJ5A 3V03A 3GA9L 2NQOA 2YDFA 1KXPD 4GG2A 5GHKA 4EMXA 2OZBB 4FIPB 2VDBA 3GQXA 2BXEA 1HK1A 2ROHA 1E7IA 4C31B 3FNMA 4GDLB 2DBUA 2EFDA 2XVVA 4OR0A 4F5VA 1BM0A 1JNBA 5IIUA 3NVKA 4E99A 2LOQA 2DBXA 1BJ5A 3V08A 4LUHA 3LU7A 4G03A 4K2CA 2QHBA 1LNSA 2BX8A 1H5WA 4OTTA 2JUHA 1E78A 4OT2A 2AJEA 5B5TA 4N0FD 4IW1A 4GDXA 4ZUXV 4LUFA 4IW2A 3UIVA 3H3AA 4NAWB 2CKXA 2BXPA 4OTUA 3JQZA 5IIHA 2XW1A 1E7FA 2DBWA 2I2ZA 1IJGA 4ZBQA 4F5UA 3FWBC 2BXQA 1GNIA 3W1SA 3PLAA 4K71A 3H37A 5ID7A 2BXAA 4JK4A 1MIVA 4WA6B 5ID9A 2E0XA 3KIKA 1H9ZA 4ZBKA 2BXOA 3CX9A 3GQUA 2XVWA 3LU6A 4TQ0A 4G01A 4F5SA 2XSIA 2XW0A 5D7GA 2NNWA 1TXUA 4BKEA 4L9KA 3JRYA 4S1YA 3SQJA 1KW2A 2VUFA 1J7EA 3WHQA 1E7HA 1N5UA 1BKEA 2BXBA 2Z8JA 4N3ZA 3V09A 2BXFA 4LB9A 2BXKA 4LA0A 4W4UB 3NVMA 1VFIA 1HK4A 2KBZA 5GIPA 3A73A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LU8 A;  2XVU A;  1HK2 A;  4PO0 A;  4Z69 A;  3B9M A;  4ZBR A;  5IIX A;  4LB2 A;  1AO6 A;  1O9X A;  1LOT A;  1UOR A;  2BXG A;  2BXI A;  1E7E A;  4N0U D;  5FUO A;  2BXC A;  2BXH A;  2I30 A;  4L8U A;  3TDL A;  5IJE A;  2BXN A;  2XVQ A;  2VUE A;  1HK3 A;  1J78 A;  1E7G A;  5IFO A;  5IJF A;  5DQF A;  1TF0 A;  4J2V A;  5HOZ A;  2BXM A;  4L9Q A;  1E7B A;  3B9L A;  5DBY A;  1E7C A;  1HA2 A;  4HGM B;  2BXL A;  1GNJ A;  1HK5 A;  1MA9 A;  4HGK A;  4G04 A;  1E7A A;  4F5T A;  2BXD A;  5IJ5 A;  3V03 A;  2YDF A;  1KXP D;  4EMX A;  5GHK A;  2VDB A;  2BXE A;  1HK1 A;  1E7I A;  4OR0 A;  2XVV A;  4F5V A;  1BM0 A;  5IIU A;  4E99 A;  1BJ5 A;  3V08 A;  4LUH A;  3LU7 A;  4G03 A;  4K2C A;  2BX8 A;  1E78 A;  4OT2 A;  4N0F D;  4IW1 A;  4LUF A;  4IW2 A;  3UIV A;  2BXP A;  3JQZ A;  5IIH A;  2XW1 A;  1E7F A;  2I2Z A;  4ZBQ A;  4F5U A;  2BXQ A;  1GNI A;  4K71 A;  2BXA A;  4JK4 A;  5ID9 A;  1H9Z A;  2BXO A;  3CX9 A;  2XVW A;  3LU6 A;  4F5S A;  2XSI A;  2XW0 A;  4BKE A;  4L9K A;  3JRY A;  4S1Y A;  3SQJ A;  1KW2 A;  2VUF A;  1J7E A;  1E7H A;  1N5U A;  1BKE A;  2BXB A;  3V09 A;  2BXF A;  4LB9 A;  2BXK A;  4LA0 A;  5ID7 A;  1HK4 A;  3A73 A; 
#chains in the Genus database with same CATH topology
 1NT2 B;  3LU8 A;  2XVU A;  2QM6 A;  4ZCG A;  2Z8I A;  1HK2 A;  1FOU A;  4PO0 A;  4Z69 A;  3B9M A;  1SB0 A;  2EFC A;  4ZBR A;  5IIX A;  4LB2 A;  4D7X A;  4BY9 C;  1AO6 A;  1O9X A;  1LOT A;  1MIW A;  1UOR A;  2BXG A;  4TQ1 A;  2BXI A;  1E7E A;  4N0U D;  2OT3 A;  5FUO A;  2BXC A;  2BXH A;  2I30 A;  2E0Y A;  4L8U A;  3TDL A;  5GIN A;  1KDX A;  4FK5 B;  5GIO A;  3KJL A;  4ZC6 A;  5IJE A;  2LXS A;  2XMO A;  3NMU A;  4GDK B;  2BXN A;  2V36 A;  3M99 C;  2XVQ A;  2VUE A;  4DHX B;  1HK3 A;  1J78 A;  1E7G A;  2EFE A;  2LQH A;  5IFO A;  5IJF A;  5DQF A;  1TF0 A;  4J2V A;  2Z8K A;  1VZS A;  2BXM A;  3G9K D;  4L9Q A;  5HOZ A;  3SIU B;  1E7B A;  3B9L A;  5DBY A;  3SIV B;  3NVI A;  1E7C A;  1MUS A;  1HA2 A;  3WHR A;  4HGM B;  2BXL A;  1GNJ A;  3ICX A;  3BPJ A;  1HK5 A;  1MA9 A;  3FWC C;  3VQI A;  4Z9O A;  4HGK A;  4G04 A;  3WHS A;  2DG5 A;  2DYO A;  3MHH B;  3A75 A;  2QMC A;  1E7A A;  4F5T A;  2BXD A;  2DYM A;  4MBE C;  4M70 B;  5BPK A;  3MHS B;  1MIY A;  2EFH A;  4FJC B;  5IJ5 A;  3V03 A;  3GA9 L;  2NQO A;  2YDF A;  1KXP D;  4GG2 A;  5GHK A;  4EMX A;  2OZB B;  1MUH A;  4FIP B;  2LXT A;  2VDB A;  3GQX A;  2BXE A;  2K0N A;  1HK1 A;  2ROH A;  1E7I A;  4C31 B;  3FNM A;  4GDL B;  2DBU A;  2EFD A;  2XVV A;  4OR0 A;  4F5V A;  1BM0 A;  1JNB A;  5IIU A;  2KWF A;  4DM0 A;  3NVK A;  4E99 A;  2LOQ A;  2DBX A;  1BJ5 A;  3V08 A;  4LUH A;  3LU7 A;  4G03 A;  4K2C A;  2QHB A;  1LNS A;  2BX8 A;  1H5W A;  4OTT A;  2JUH A;  1E78 A;  4OT2 A;  2AJE A;  5B5T A;  4N0F D;  4IW1 A;  4GDX A;  4ZUX V;  4I9O A;  4LUF A;  4IW2 A;  3UIV A;  3H3A A;  2LQI A;  2CKX A;  4NAW B;  2BXP A;  4OTU A;  3JQZ A;  5IIH A;  2XW1 A;  1E7F A;  2DBW A;  2I2Z A;  1IJG A;  4ZBQ A;  2AGH B;  4F5U A;  3FWB C;  2BXQ A;  1GNI A;  3W1S A;  3PLA A;  4K71 A;  3H37 A;  5ID7 A;  2BXA A;  4JK4 A;  1MIV A;  4WA6 B;  5ID9 A;  2E0X A;  3KIK A;  1H9Z A;  4ZBK A;  2BXO A;  3CX9 A;  3GQU A;  2XVW A;  3LU6 A;  4TQ0 A;  4G01 A;  2GUT A;  4F5S A;  2XSI A;  2XW0 A;  3ECP A;  1MM8 A;  5D7G A;  2NNW A;  1TXU A;  4BKE A;  4L9K A;  3JRY A;  4S1Y A;  3SQJ A;  1KW2 A;  2VUF A;  1J7E A;  3WHQ A;  1E7H A;  1N5U A;  1BKE A;  2BXB A;  2Z8J A;  4N3Z A;  3V09 A;  2BXF A;  4LB9 A;  2BXK A;  4LA0 A;  4W4U B;  3NVM A;  1VFI A;  1HK4 A;  2KBZ A;  5GIP A;  3A73 A; 
#chains in the Genus database with same CATH homology
 1NT2 B;  3LU8 A;  2XVU A;  2QM6 A;  4ZCG A;  2Z8I A;  1HK2 A;  1FOU A;  4PO0 A;  4Z69 A;  3B9M A;  2EFC A;  4ZBR A;  5IIX A;  4LB2 A;  4BY9 C;  1AO6 A;  1O9X A;  1LOT A;  1MIW A;  1UOR A;  2BXG A;  4TQ1 A;  2BXI A;  1E7E A;  4N0U D;  2OT3 A;  5FUO A;  2BXC A;  2BXH A;  2I30 A;  2E0Y A;  4L8U A;  3TDL A;  5GIN A;  4FK5 B;  5GIO A;  3KJL A;  4ZC6 A;  5IJE A;  2XMO A;  3NMU A;  4GDK B;  2BXN A;  2V36 A;  3M99 C;  2XVQ A;  2VUE A;  4DHX B;  1HK3 A;  1J78 A;  1E7G A;  2EFE A;  5IFO A;  5IJF A;  5DQF A;  1TF0 A;  4J2V A;  2Z8K A;  1VZS A;  2BXM A;  3G9K D;  4L9Q A;  5HOZ A;  3SIU B;  1E7B A;  3B9L A;  5DBY A;  3SIV B;  3NVI A;  1E7C A;  1HA2 A;  3WHR A;  4HGM B;  2BXL A;  1GNJ A;  3ICX A;  1HK5 A;  1MA9 A;  3FWC C;  3VQI A;  4Z9O A;  4HGK A;  4G04 A;  3WHS A;  2DG5 A;  2DYO A;  3MHH B;  3A75 A;  2QMC A;  1E7A A;  4F5T A;  2BXD A;  2DYM A;  4MBE C;  4M70 B;  5BPK A;  3MHS B;  1MIY A;  2EFH A;  4FJC B;  5IJ5 A;  3V03 A;  3GA9 L;  2NQO A;  2YDF A;  1KXP D;  4GG2 A;  5GHK A;  4EMX A;  2OZB B;  4FIP B;  2VDB A;  3GQX A;  2BXE A;  1HK1 A;  2ROH A;  1E7I A;  4C31 B;  3FNM A;  4GDL B;  2DBU A;  2EFD A;  2XVV A;  4OR0 A;  4F5V A;  1BM0 A;  1JNB A;  5IIU A;  3NVK A;  4E99 A;  2LOQ A;  2DBX A;  1BJ5 A;  3V08 A;  4LUH A;  3LU7 A;  4G03 A;  4K2C A;  2QHB A;  1LNS A;  2BX8 A;  1H5W A;  4OTT A;  2JUH A;  1E78 A;  4OT2 A;  2AJE A;  5B5T A;  4N0F D;  4IW1 A;  4GDX A;  4ZUX V;  4LUF A;  4IW2 A;  3UIV A;  3H3A A;  4NAW B;  2CKX A;  2BXP A;  4OTU A;  3JQZ A;  5IIH A;  2XW1 A;  1E7F A;  2DBW A;  2I2Z A;  1IJG A;  4ZBQ A;  4F5U A;  3FWB C;  2BXQ A;  1GNI A;  3W1S A;  3PLA A;  4K71 A;  3H37 A;  5ID7 A;  2BXA A;  4JK4 A;  1MIV A;  4WA6 B;  5ID9 A;  2E0X A;  3KIK A;  1H9Z A;  4ZBK A;  2BXO A;  3CX9 A;  3GQU A;  2XVW A;  3LU6 A;  4TQ0 A;  4G01 A;  4F5S A;  2XSI A;  2XW0 A;  5D7G A;  2NNW A;  1TXU A;  4BKE A;  4L9K A;  3JRY A;  4S1Y A;  3SQJ A;  1KW2 A;  2VUF A;  1J7E A;  3WHQ A;  1E7H A;  1N5U A;  1BKE A;  2BXB A;  2Z8J A;  4N3Z A;  3V09 A;  2BXF A;  4LB9 A;  2BXK A;  4LA0 A;  4W4U B;  3NVM A;  1VFI A;  1HK4 A;  2KBZ A;  5GIP A;  3A73 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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