2Z8JA

Crystal structure of escherichia coli gamma-glutamyltranspeptidase in complex with azaserine prepared in the dark
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
350
structure length
350
Chain Sequence
EDVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Gamma-glutamyltranspeptidase
total genus 99
structure length 350
sequence length 350
chains with identical sequence C
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2007-09-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2z8jA02
5B5TA 4OTUA 2NQOA 2Z8JA 3WHQA 2V36A 3A75A 2DBUA 2Z8KA 2QM6A 4Z9OA 2E0XA 4ZBKA 3FNMA 2Z8IA 4ZC6A 3WHRA 5BPKA 4GDXA 4ZCGA 4OTTA 2DBXA 2E0YA 2DG5A 3WHSA 4GG2A 2QMCA 2DBWA
chains in the Genus database with same CATH superfamily
2YDFA 4DM0A 3A73A 2BXLA 3VQIA 1UORA 3GQXA 1MUSA 2LOQA 1J78A 1IJGA 2LQHA 1KXPD 2QM6A 1GNJA 1H9ZA 1HK3A 1HK1A 4FIPB 4GDLB 1BM0A 2AJEA 1E7AA 4IW1A 4Z9OA 3SIVB 2EFCA 1GNIA 5ID9A 4TQ0A 3PLAA 5IIUA 1HK2A 4OT2A 2BXBA 4TQ1A 4D7XA 3MHSB 3V03A 5BPKA 3BPJA 2BXQA 3V08A 4ZUXV 3H37A 2BXFA 3G9KD 1BJ5A 4MBEC 5GINA 2ROHA 4N0FD 2NNWA 3LU8A 5B5TA 4F5UA 4OTUA 2BXNA 2Z8JA 3WHQA 4BY9C 2JUHA 1MM8A 2XVUA 4L9KA 2EFDA 4N3ZA 3SIUB 2XVVA 2VUEA 4N0UD 2BXAA 2LXSA 3CX9A 3FWBC 3MHHB 4FJCB 4HGMB 1E7CA 1VFIA 1E7HA 4C31B 3JRYA 1LOTA 3FNMA 1O9XA 1HK4A 2XW0A 2Z8IA 2LXTA 2CKXA 4FK5B 4ZC6A 4F5VA 1NT2B 3KJLA 1TF0A 2DYOA 4LUHA 3JQZA 4OTTA 3NMUA 2DBXA 2QHBA 2E0YA 2BXCA 4OR0A 3NVMA 2VDBA 4GG2A 4JK4A 3B9MA 1E78A 1LNSA 1TXUA 1E7FA 2BXHA 2QMCA 2VUFA 2XVQA 5IIHA 2K0NA 2KWFA 3WHSA 1HK5A 2DYMA 5DQFA 4K2CA 4G04A 4L9QA 5GIPA 3A75A 4W4UB 4ZBRA 4BKEA 3GQUA 4K71A 2DBUA 2Z8KA 2BXIA 4F5SA 4LB9A 4ZBKA 3TDLA 1E7BA 2BXOA 2BX8A 3GA9L 1N5UA 2BXEA 1SB0A 5IIXA 5IJFA 1H5WA 3M99C 1AO6A 1MUHA 3WHRA 5GHKA 3FWCC 4S1YA 2OZBB 3UIVA 4GDXA 5IJ5A 3B9LA 1KW2A 3H3AA 1VZSA 5IJEA 4L8UA 1MIWA 5IFOA 4I9OA 2KBZA 3NVIA 5DBYA 1BKEA 2XMOA 1E7EA 2DG5A 4E99A 2AGHB 4PO0A 4EMXA 4J2VA 3NVKA 2OT3A 2NQOA 5ID7A 2V36A 4LB2A 5HOZA 2EFEA 2LQIA 3SQJA 1KDXA 3ECPA 1HA2A 2BXMA 2I2ZA 4NAWB 4LA0A 1FOUA 1MIVA 2BXPA 2BXGA 3LU7A 4F5TA 4ZBQA 1J7EA 2E0XA 2BXDA 3KIKA 2GUTA 5D7GA 3LU6A 5FUOA 2XVWA 1JNBA 1E7IA 2BXKA 1MA9A 2EFHA 2XSIA 4LUFA 4ZCGA 4HGKA 4M70B 3W1SA 4Z69A 4G01A 4G03A 5GIOA 1MIYA 3ICXA 4GDKB 2I30A 4DHXB 4WA6B 4IW2A 2XW1A 3V09A 1E7GA 2DBWA
chains in the Genus database with same CATH topology
2YDFA 3A73A 2BXLA 3VQIA 1UORA 3GQXA 2LOQA 1J78A 1IJGA 1KXPD 2QM6A 1GNJA 1H9ZA 1HK3A 1HK1A 4FIPB 4GDLB 1BM0A 2AJEA 1E7AA 4IW1A 4Z9OA 3SIVB 2EFCA 1GNIA 5ID9A 4TQ0A 3PLAA 5IIUA 1HK2A 4OT2A 2BXBA 4TQ1A 3MHSB 3V03A 5BPKA 2BXQA 3V08A 4ZUXV 3H37A 2BXFA 3G9KD 1BJ5A 4MBEC 5GINA 2ROHA 4N0FD 2NNWA 3LU8A 5B5TA 4F5UA 4OTUA 2BXNA 2Z8JA 3WHQA 4BY9C 2JUHA 2XVUA 4L9KA 2EFDA 4N3ZA 3SIUB 2XVVA 2VUEA 4N0UD 2BXAA 3CX9A 3FWBC 3MHHB 4FJCB 4HGMB 1E7CA 1VFIA 1E7HA 4C31B 3JRYA 1LOTA 3FNMA 1O9XA 1HK4A 2XW0A 2Z8IA 4ZC6A 2CKXA 4FK5B 4F5VA 1NT2B 3KJLA 1TF0A 2DYOA 4LUHA 3JQZA 4OTTA 3NMUA 2DBXA 2QHBA 2E0YA 2BXCA 4OR0A 3NVMA 2VDBA 4GG2A 4JK4A 3B9MA 1E78A 1LNSA 1TXUA 1E7FA 2BXHA 2QMCA 2VUFA 2XVQA 5IIHA 3WHSA 1HK5A 2DYMA 5DQFA 4K2CA 4G04A 4L9QA 5GIPA 3A75A 4W4UB 4ZBRA 4BKEA 3GQUA 4K71A 2DBUA 2Z8KA 2BXIA 4F5SA 4LB9A 4ZBKA 3TDLA 1E7BA 2BXOA 2BX8A 3GA9L 1N5UA 2BXEA 5IIXA 5IJFA 1H5WA 3M99C 1AO6A 3WHRA 5GHKA 3FWCC 4S1YA 2OZBB 3UIVA 4GDXA 5IJ5A 3B9LA 1KW2A 3H3AA 1VZSA 5IJEA 4L8UA 1MIWA 5IFOA 3NVIA 2KBZA 5DBYA 1BKEA 2XMOA 1E7EA 2DG5A 4E99A 4PO0A 4EMXA 4J2VA 3NVKA 2OT3A 2NQOA 5ID7A 2V36A 4LB2A 5HOZA 2EFEA 3SQJA 1HA2A 2BXMA 2I2ZA 4NAWB 4LA0A 1FOUA 1MIVA 2BXPA 2BXGA 3LU7A 4F5TA 4ZBQA 1J7EA 2E0XA 2BXDA 3KIKA 5D7GA 3LU6A 5FUOA 2XVWA 1JNBA 1E7IA 2BXKA 1MA9A 2EFHA 2XSIA 4LUFA 4ZCGA 4HGKA 4M70B 3W1SA 4Z69A 4G01A 4G03A 5GIOA 1MIYA 3ICXA 4GDKB 2I30A 4DHXB 4WA6B 4IW2A 2XW1A 3V09A 1E7GA 2DBWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5B5T A;  4OTU A;  2NQO A;  2Z8J A;  3WHQ A;  2V36 A;  3A75 A;  2DBU A;  2Z8K A;  2QM6 A;  4Z9O A;  2E0X A;  4ZBK A;  3FNM A;  2Z8I A;  4ZC6 A;  3WHR A;  5BPK A;  4GDX A;  4ZCG A;  4OTT A;  2DBX A;  2E0Y A;  2DG5 A;  3WHS A;  4GG2 A;  2QMC A;  2DBW A; 
#chains in the Genus database with same CATH topology
 2YDF A;  4DM0 A;  3A73 A;  2BXL A;  3VQI A;  1UOR A;  3GQX A;  1MUS A;  2LOQ A;  1J78 A;  1IJG A;  2LQH A;  1KXP D;  2QM6 A;  1GNJ A;  1H9Z A;  1HK3 A;  1HK1 A;  4FIP B;  4GDL B;  1BM0 A;  2AJE A;  1E7A A;  4IW1 A;  4Z9O A;  3SIV B;  2EFC A;  1GNI A;  5ID9 A;  4TQ0 A;  3PLA A;  5IIU A;  1HK2 A;  4OT2 A;  2BXB A;  4TQ1 A;  4D7X A;  3MHS B;  3V03 A;  5BPK A;  3BPJ A;  2BXQ A;  3V08 A;  4ZUX V;  3H37 A;  2BXF A;  3G9K D;  1BJ5 A;  4MBE C;  5GIN A;  2ROH A;  4N0F D;  2NNW A;  3LU8 A;  5B5T A;  4F5U A;  4OTU A;  2BXN A;  2Z8J A;  3WHQ A;  4BY9 C;  2JUH A;  1MM8 A;  2XVU A;  4L9K A;  2EFD A;  4N3Z A;  3SIU B;  2XVV A;  2VUE A;  4N0U D;  2BXA A;  2LXS A;  3CX9 A;  3FWB C;  3MHH B;  4FJC B;  4HGM B;  1E7C A;  1VFI A;  1E7H A;  4C31 B;  3JRY A;  1LOT A;  3FNM A;  1O9X A;  1HK4 A;  2XW0 A;  2Z8I A;  2LXT A;  2CKX A;  4FK5 B;  4ZC6 A;  4F5V A;  1NT2 B;  3KJL A;  1TF0 A;  2DYO A;  4LUH A;  3JQZ A;  4OTT A;  3NMU A;  2DBX A;  2QHB A;  2E0Y A;  2BXC A;  4OR0 A;  3NVM A;  2VDB A;  4GG2 A;  4JK4 A;  3B9M A;  1E78 A;  1LNS A;  1TXU A;  1E7F A;  2BXH A;  2QMC A;  2VUF A;  2XVQ A;  5IIH A;  2K0N A;  2KWF A;  3WHS A;  1HK5 A;  2DYM A;  5DQF A;  4K2C A;  4G04 A;  4L9Q A;  5GIP A;  3A75 A;  4W4U B;  4ZBR A;  4BKE A;  3GQU A;  4K71 A;  2DBU A;  2Z8K A;  2BXI A;  4F5S A;  4LB9 A;  4ZBK A;  3TDL A;  1E7B A;  2BXO A;  2BX8 A;  3GA9 L;  1N5U A;  2BXE A;  1SB0 A;  5IIX A;  5IJF A;  1H5W A;  3M99 C;  1AO6 A;  1MUH A;  3WHR A;  5GHK A;  3FWC C;  4S1Y A;  2OZB B;  3UIV A;  4GDX A;  5IJ5 A;  3B9L A;  1KW2 A;  3H3A A;  1VZS A;  5IJE A;  4L8U A;  1MIW A;  5IFO A;  4I9O A;  2KBZ A;  3NVI A;  5DBY A;  1BKE A;  2XMO A;  1E7E A;  2DG5 A;  4E99 A;  2AGH B;  4PO0 A;  4EMX A;  4J2V A;  3NVK A;  2OT3 A;  2NQO A;  5ID7 A;  2V36 A;  4LB2 A;  5HOZ A;  2EFE A;  2LQI A;  3SQJ A;  1KDX A;  3ECP A;  1HA2 A;  2BXM A;  2I2Z A;  4NAW B;  4LA0 A;  1FOU A;  1MIV A;  2BXP A;  2BXG A;  3LU7 A;  4F5T A;  4ZBQ A;  1J7E A;  2E0X A;  2BXD A;  3KIK A;  2GUT A;  5D7G A;  3LU6 A;  5FUO A;  2XVW A;  1JNB A;  1E7I A;  2BXK A;  1MA9 A;  2EFH A;  2XSI A;  4LUF A;  4ZCG A;  4HGK A;  4M70 B;  3W1S A;  4Z69 A;  4G01 A;  4G03 A;  5GIO A;  1MIY A;  3ICX A;  4GDK B;  2I30 A;  4DHX B;  4WA6 B;  4IW2 A;  2XW1 A;  3V09 A;  1E7G A;  2DBW A; 
#chains in the Genus database with same CATH homology
 2YDF A;  3A73 A;  2BXL A;  3VQI A;  1UOR A;  3GQX A;  2LOQ A;  1J78 A;  1IJG A;  1KXP D;  2QM6 A;  1GNJ A;  1H9Z A;  1HK3 A;  1HK1 A;  4FIP B;  4GDL B;  1BM0 A;  2AJE A;  1E7A A;  4IW1 A;  4Z9O A;  3SIV B;  2EFC A;  1GNI A;  5ID9 A;  4TQ0 A;  3PLA A;  5IIU A;  1HK2 A;  4OT2 A;  2BXB A;  4TQ1 A;  3MHS B;  3V03 A;  5BPK A;  2BXQ A;  3V08 A;  4ZUX V;  3H37 A;  2BXF A;  3G9K D;  1BJ5 A;  4MBE C;  5GIN A;  2ROH A;  4N0F D;  2NNW A;  3LU8 A;  5B5T A;  4F5U A;  4OTU A;  2BXN A;  2Z8J A;  3WHQ A;  4BY9 C;  2JUH A;  2XVU A;  4L9K A;  2EFD A;  4N3Z A;  3SIU B;  2XVV A;  2VUE A;  4N0U D;  2BXA A;  3CX9 A;  3FWB C;  3MHH B;  4FJC B;  4HGM B;  1E7C A;  1VFI A;  1E7H A;  4C31 B;  3JRY A;  1LOT A;  3FNM A;  1O9X A;  1HK4 A;  2XW0 A;  2Z8I A;  4ZC6 A;  2CKX A;  4FK5 B;  4F5V A;  1NT2 B;  3KJL A;  1TF0 A;  2DYO A;  4LUH A;  3JQZ A;  4OTT A;  3NMU A;  2DBX A;  2QHB A;  2E0Y A;  2BXC A;  4OR0 A;  3NVM A;  2VDB A;  4GG2 A;  4JK4 A;  3B9M A;  1E78 A;  1LNS A;  1TXU A;  1E7F A;  2BXH A;  2QMC A;  2VUF A;  2XVQ A;  5IIH A;  3WHS A;  1HK5 A;  2DYM A;  5DQF A;  4K2C A;  4G04 A;  4L9Q A;  5GIP A;  3A75 A;  4W4U B;  4ZBR A;  4BKE A;  3GQU A;  4K71 A;  2DBU A;  2Z8K A;  2BXI A;  4F5S A;  4LB9 A;  4ZBK A;  3TDL A;  1E7B A;  2BXO A;  2BX8 A;  3GA9 L;  1N5U A;  2BXE A;  5IIX A;  5IJF A;  1H5W A;  3M99 C;  1AO6 A;  3WHR A;  5GHK A;  3FWC C;  4S1Y A;  2OZB B;  3UIV A;  4GDX A;  5IJ5 A;  3B9L A;  1KW2 A;  3H3A A;  1VZS A;  5IJE A;  4L8U A;  1MIW A;  5IFO A;  3NVI A;  2KBZ A;  5DBY A;  1BKE A;  2XMO A;  1E7E A;  2DG5 A;  4E99 A;  4PO0 A;  4EMX A;  4J2V A;  3NVK A;  2OT3 A;  2NQO A;  5ID7 A;  2V36 A;  4LB2 A;  5HOZ A;  2EFE A;  3SQJ A;  1HA2 A;  2BXM A;  2I2Z A;  4NAW B;  4LA0 A;  1FOU A;  1MIV A;  2BXP A;  2BXG A;  3LU7 A;  4F5T A;  4ZBQ A;  1J7E A;  2E0X A;  2BXD A;  3KIK A;  5D7G A;  3LU6 A;  5FUO A;  2XVW A;  1JNB A;  1E7I A;  2BXK A;  1MA9 A;  2EFH A;  2XSI A;  4LUF A;  4ZCG A;  4HGK A;  4M70 B;  3W1S A;  4Z69 A;  4G01 A;  4G03 A;  5GIO A;  1MIY A;  3ICX A;  4GDK B;  2I30 A;  4DHX B;  4WA6 B;  4IW2 A;  2XW1 A;  3V09 A;  1E7G A;  2DBW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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