2Z8JA

Crystal structure of escherichia coli gamma-glutamyltranspeptidase in complex with azaserine prepared in the dark
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
350
structure length
350
Chain Sequence
EDVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Gamma-glutamyltranspeptidase
total genus 99
structure length 350
sequence length 350
chains with identical sequence C
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2007-09-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2z8jA02
2Z8JA 2DG5A 4ZCGA 4Z9OA 4GDXA 2E0XA 4OTTA 2V36A 3A75A 4ZBKA 3WHRA 2QM6A 2QMCA 3WHQA 5BPKA 4GG2A 2DBUA 2Z8KA 2DBWA 3FNMA 2E0YA 4OTUA 4ZC6A 2NQOA 2Z8IA 3WHSA 5B5TA 2DBXA
chains in the Genus database with same CATH superfamily
4Z69A 1MUHA 1SB0A 3GQUA 5ID7A 4W4UB 3H3AA 5IIXA 2BXNA 1E7EA 4LB2A 4GDXA 2LQIA 3V08A 2OZBB 2E0XA 1J78A 4LA0A 1LOTA 4TQ1A 1VZSA 1LNSA 2XVUA 4OTTA 4OT2A 5FUOA 1MIVA 1E7HA 2XVVA 3A73A 1MUSA 2XMOA 4L9KA 3WHQA 2VUEA 1J7EA 5BPKA 1H9ZA 2EFDA 4GG2A 4F5VA 1NT2B 1GNIA 2BXCA 1VFIA 2Z8KA 2BXAA 2OT3A 4OTUA 1H5WA 1E7CA 2NQOA 2Z8IA 4ZC6A 3FWBC 3WHSA 5IIHA 2BXFA 5B5TA 4TQ0A 4MBEC 2DBXA 1O9XA 1E7BA 2KBZA 2BXEA 1N5UA 3MHHB 2Z8JA 3M99C 1BKEA 1GNJA 2DYMA 3MHSB 4EMXA 1KW2A 4BY9C 4N3ZA 3JRYA 3NVIA 3ECPA 1TF0A 1BM0A 3SQJA 1HK5A 4OR0A 2XSIA 3LU8A 2AJEA 1MM8A 2JUHA 5IJEA 1E7AA 4IW1A 3JQZA 5D7GA 1AO6A 4ZBRA 2XW0A 4FK5B 4PO0A 3SIVB 2LQHA 3G9KD 4GDLB 2DBUA 3H37A 4DHXB 2DBWA 4D7XA 4M70B 3NMUA 2BXOA 4FJCB 4NAWB 5IIUA 3B9LA 4F5UA 1MIWA 3TDLA 2BXMA 5GIPA 2K0NA 4I9OA 4LUHA 4LUFA 4WA6B 2AGHB 2XVWA 4FIPB 3UIVA 1HK4A 1E7IA 3W1SA 2GUTA 4IW2A 4F5SA 4Z9OA 3B9MA 2BXDA 4G01A 2XW1A 3FWCC 3KIKA 4JK4A 4N0FD 4N0UD 3V09A 4HGKA 3A75A 1E7GA 2QM6A 4DM0A 5GHKA 1HA2A 2BXLA 3BPJA 4L8UA 2EFCA 1BJ5A 2BX8A 2BXPA 4L9QA 4C31B 2BXGA 5DQFA 4F5TA 3ICXA 2BXKA 3FNMA 1UORA 2YDFA 3NVKA 4J2VA 5GINA 2BXBA 2EFEA 4ZBQA 3CX9A 2KWFA 5IJFA 1TXUA 1HK1A 2CKXA 2DYOA 2LXTA 2DG5A 2NNWA 2BXQA 4GDKB 4ZCGA 5HOZA 2I2ZA 4HGMB 3SIUB 1JNBA 2VUFA 2I30A 3KJLA 4G04A 4LB9A 2BXIA 4BKEA 3V03A 4ZUXV 1HK3A 5GIOA 2LXSA 1E7FA 2ROHA 2V36A 1KDXA 3VQIA 5IFOA 4K2CA 4ZBKA 3WHRA 3NVMA 3GA9L 2XVQA 2QMCA 4K71A 3PLAA 2LOQA 1FOUA 1MA9A 5ID9A 1E78A 2BXHA 5IJ5A 5DBYA 2EFHA 1IJGA 1HK2A 4G03A 3GQXA 2E0YA 1KXPD 3LU7A 4S1YA 1MIYA 2VDBA 3LU6A 4E99A 2QHBA
chains in the Genus database with same CATH topology
4Z69A 3GQUA 5ID7A 4W4UB 3H3AA 5IIXA 2BXNA 1E7EA 4LB2A 4GDXA 3V08A 2OZBB 2E0XA 1J78A 4LA0A 1LOTA 4TQ1A 1VZSA 1LNSA 2XVUA 4OTTA 4OT2A 5FUOA 1MIVA 1E7HA 2XVVA 3A73A 2XMOA 4L9KA 3WHQA 2VUEA 1J7EA 5BPKA 1H9ZA 2EFDA 4GG2A 4F5VA 1NT2B 1GNIA 2BXCA 1VFIA 2Z8KA 2BXAA 2OT3A 4OTUA 1H5WA 1E7CA 2NQOA 2Z8IA 4ZC6A 3FWBC 3WHSA 5IIHA 2BXFA 5B5TA 4TQ0A 4MBEC 2DBXA 1O9XA 1E7BA 2KBZA 2BXEA 1N5UA 3MHHB 2Z8JA 3M99C 1BKEA 1GNJA 2DYMA 3MHSB 4EMXA 1KW2A 4BY9C 4N3ZA 3JRYA 3NVIA 1TF0A 1BM0A 3SQJA 1HK5A 4OR0A 2XSIA 3LU8A 2AJEA 2JUHA 5IJEA 1E7AA 4IW1A 3JQZA 5D7GA 1AO6A 4ZBRA 2XW0A 4FK5B 4PO0A 3SIVB 3G9KD 4GDLB 2DBUA 3H37A 4DHXB 2DBWA 4M70B 3NMUA 2BXOA 4FJCB 4NAWB 5IIUA 3B9LA 4F5UA 1MIWA 3TDLA 2BXMA 5GIPA 4LUHA 4LUFA 4WA6B 2XVWA 4FIPB 3UIVA 1HK4A 1E7IA 3W1SA 4F5SA 4IW2A 4Z9OA 3B9MA 2BXDA 4G01A 2XW1A 3FWCC 3KIKA 4JK4A 4N0FD 4N0UD 3V09A 4HGKA 3A75A 1E7GA 2QM6A 5GHKA 1HA2A 2BXLA 4L8UA 2EFCA 1BJ5A 2BX8A 2BXPA 4L9QA 4C31B 2BXGA 5DQFA 4F5TA 3ICXA 2BXKA 3FNMA 1UORA 2YDFA 3NVKA 4J2VA 5GINA 2BXBA 2EFEA 4ZBQA 3CX9A 5IJFA 1TXUA 1HK1A 2CKXA 2DYOA 2NNWA 2DG5A 4GDKB 2BXQA 4ZCGA 5HOZA 3SIUB 2I2ZA 4HGMB 1JNBA 2VUFA 2I30A 3KJLA 4G04A 4LB9A 2BXIA 4BKEA 3V03A 4ZUXV 1HK3A 5GIOA 1E7FA 2ROHA 2V36A 3VQIA 5IFOA 4K2CA 4ZBKA 3WHRA 3NVMA 3GA9L 2XVQA 2QMCA 4K71A 3PLAA 2LOQA 1FOUA 1MA9A 5ID9A 1E78A 2BXHA 5IJ5A 5DBYA 2EFHA 1IJGA 1HK2A 4G03A 3GQXA 2E0YA 1KXPD 3LU7A 4S1YA 1MIYA 2VDBA 3LU6A 4E99A 2QHBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z8J A;  2DG5 A;  4ZCG A;  4Z9O A;  4GDX A;  2E0X A;  4OTT A;  2V36 A;  3A75 A;  4ZBK A;  3WHR A;  2QM6 A;  2QMC A;  3WHQ A;  5BPK A;  4GG2 A;  2DBU A;  2Z8K A;  2DBW A;  3FNM A;  2E0Y A;  4OTU A;  4ZC6 A;  2NQO A;  2Z8I A;  3WHS A;  5B5T A;  2DBX A; 
#chains in the Genus database with same CATH topology
 4Z69 A;  1MUH A;  1SB0 A;  3GQU A;  5ID7 A;  4W4U B;  3H3A A;  5IIX A;  2BXN A;  1E7E A;  4LB2 A;  4GDX A;  2LQI A;  3V08 A;  2OZB B;  2E0X A;  1J78 A;  4LA0 A;  1LOT A;  4TQ1 A;  1VZS A;  1LNS A;  2XVU A;  4OTT A;  4OT2 A;  5FUO A;  1MIV A;  1E7H A;  2XVV A;  3A73 A;  1MUS A;  2XMO A;  4L9K A;  3WHQ A;  2VUE A;  1J7E A;  5BPK A;  1H9Z A;  2EFD A;  4GG2 A;  4F5V A;  1NT2 B;  1GNI A;  2BXC A;  1VFI A;  2Z8K A;  2BXA A;  2OT3 A;  4OTU A;  1H5W A;  1E7C A;  2NQO A;  2Z8I A;  4ZC6 A;  3FWB C;  3WHS A;  5IIH A;  2BXF A;  5B5T A;  4TQ0 A;  4MBE C;  2DBX A;  1O9X A;  1E7B A;  2KBZ A;  2BXE A;  1N5U A;  3MHH B;  2Z8J A;  3M99 C;  1BKE A;  1GNJ A;  2DYM A;  3MHS B;  4EMX A;  1KW2 A;  4BY9 C;  4N3Z A;  3JRY A;  3NVI A;  3ECP A;  1TF0 A;  1BM0 A;  3SQJ A;  1HK5 A;  4OR0 A;  2XSI A;  3LU8 A;  2AJE A;  1MM8 A;  2JUH A;  5IJE A;  1E7A A;  4IW1 A;  3JQZ A;  5D7G A;  1AO6 A;  4ZBR A;  2XW0 A;  4FK5 B;  4PO0 A;  3SIV B;  2LQH A;  3G9K D;  4GDL B;  2DBU A;  3H37 A;  4DHX B;  2DBW A;  4D7X A;  4M70 B;  3NMU A;  2BXO A;  4FJC B;  4NAW B;  5IIU A;  3B9L A;  4F5U A;  1MIW A;  3TDL A;  2BXM A;  5GIP A;  2K0N A;  4I9O A;  4LUH A;  4LUF A;  4WA6 B;  2AGH B;  2XVW A;  4FIP B;  3UIV A;  1HK4 A;  1E7I A;  3W1S A;  2GUT A;  4IW2 A;  4F5S A;  4Z9O A;  3B9M A;  2BXD A;  4G01 A;  2XW1 A;  3FWC C;  3KIK A;  4JK4 A;  4N0F D;  4N0U D;  3V09 A;  4HGK A;  3A75 A;  1E7G A;  2QM6 A;  4DM0 A;  5GHK A;  1HA2 A;  2BXL A;  3BPJ A;  4L8U A;  2EFC A;  1BJ5 A;  2BX8 A;  2BXP A;  4L9Q A;  4C31 B;  2BXG A;  5DQF A;  4F5T A;  3ICX A;  2BXK A;  3FNM A;  1UOR A;  2YDF A;  3NVK A;  4J2V A;  5GIN A;  2BXB A;  2EFE A;  4ZBQ A;  3CX9 A;  2KWF A;  5IJF A;  1TXU A;  1HK1 A;  2CKX A;  2DYO A;  2LXT A;  2DG5 A;  2NNW A;  2BXQ A;  4GDK B;  4ZCG A;  5HOZ A;  2I2Z A;  4HGM B;  3SIU B;  1JNB A;  2VUF A;  2I30 A;  3KJL A;  4G04 A;  4LB9 A;  2BXI A;  4BKE A;  3V03 A;  4ZUX V;  1HK3 A;  5GIO A;  2LXS A;  1E7F A;  2ROH A;  2V36 A;  1KDX A;  3VQI A;  5IFO A;  4K2C A;  4ZBK A;  3WHR A;  3NVM A;  3GA9 L;  2XVQ A;  2QMC A;  4K71 A;  3PLA A;  2LOQ A;  1FOU A;  1MA9 A;  5ID9 A;  1E78 A;  2BXH A;  5IJ5 A;  5DBY A;  2EFH A;  1IJG A;  1HK2 A;  4G03 A;  3GQX A;  2E0Y A;  1KXP D;  3LU7 A;  4S1Y A;  1MIY A;  2VDB A;  3LU6 A;  4E99 A;  2QHB A; 
#chains in the Genus database with same CATH homology
 4Z69 A;  3GQU A;  5ID7 A;  4W4U B;  3H3A A;  5IIX A;  2BXN A;  1E7E A;  4LB2 A;  4GDX A;  3V08 A;  2OZB B;  2E0X A;  1J78 A;  4LA0 A;  1LOT A;  4TQ1 A;  1VZS A;  1LNS A;  2XVU A;  4OTT A;  4OT2 A;  5FUO A;  1MIV A;  1E7H A;  2XVV A;  3A73 A;  2XMO A;  4L9K A;  3WHQ A;  2VUE A;  1J7E A;  5BPK A;  1H9Z A;  2EFD A;  4GG2 A;  4F5V A;  1NT2 B;  1GNI A;  2BXC A;  1VFI A;  2Z8K A;  2BXA A;  2OT3 A;  4OTU A;  1H5W A;  1E7C A;  2NQO A;  2Z8I A;  4ZC6 A;  3FWB C;  3WHS A;  5IIH A;  2BXF A;  5B5T A;  4TQ0 A;  4MBE C;  2DBX A;  1O9X A;  1E7B A;  2KBZ A;  2BXE A;  1N5U A;  3MHH B;  2Z8J A;  3M99 C;  1BKE A;  1GNJ A;  2DYM A;  3MHS B;  4EMX A;  1KW2 A;  4BY9 C;  4N3Z A;  3JRY A;  3NVI A;  1TF0 A;  1BM0 A;  3SQJ A;  1HK5 A;  4OR0 A;  2XSI A;  3LU8 A;  2AJE A;  2JUH A;  5IJE A;  1E7A A;  4IW1 A;  3JQZ A;  5D7G A;  1AO6 A;  4ZBR A;  2XW0 A;  4FK5 B;  4PO0 A;  3SIV B;  3G9K D;  4GDL B;  2DBU A;  3H37 A;  4DHX B;  2DBW A;  4M70 B;  3NMU A;  2BXO A;  4FJC B;  4NAW B;  5IIU A;  3B9L A;  4F5U A;  1MIW A;  3TDL A;  2BXM A;  5GIP A;  4LUH A;  4LUF A;  4WA6 B;  2XVW A;  4FIP B;  3UIV A;  1HK4 A;  1E7I A;  3W1S A;  4F5S A;  4IW2 A;  4Z9O A;  3B9M A;  2BXD A;  4G01 A;  2XW1 A;  3FWC C;  3KIK A;  4JK4 A;  4N0F D;  4N0U D;  3V09 A;  4HGK A;  3A75 A;  1E7G A;  2QM6 A;  5GHK A;  1HA2 A;  2BXL A;  4L8U A;  2EFC A;  1BJ5 A;  2BX8 A;  2BXP A;  4L9Q A;  4C31 B;  2BXG A;  5DQF A;  4F5T A;  3ICX A;  2BXK A;  3FNM A;  1UOR A;  2YDF A;  3NVK A;  4J2V A;  5GIN A;  2BXB A;  2EFE A;  4ZBQ A;  3CX9 A;  5IJF A;  1TXU A;  1HK1 A;  2CKX A;  2DYO A;  2NNW A;  2DG5 A;  4GDK B;  2BXQ A;  4ZCG A;  5HOZ A;  3SIU B;  2I2Z A;  4HGM B;  1JNB A;  2VUF A;  2I30 A;  3KJL A;  4G04 A;  4LB9 A;  2BXI A;  4BKE A;  3V03 A;  4ZUX V;  1HK3 A;  5GIO A;  1E7F A;  2ROH A;  2V36 A;  3VQI A;  5IFO A;  4K2C A;  4ZBK A;  3WHR A;  3NVM A;  3GA9 L;  2XVQ A;  2QMC A;  4K71 A;  3PLA A;  2LOQ A;  1FOU A;  1MA9 A;  5ID9 A;  1E78 A;  2BXH A;  5IJ5 A;  5DBY A;  2EFH A;  1IJG A;  1HK2 A;  4G03 A;  3GQX A;  2E0Y A;  1KXP D;  3LU7 A;  4S1Y A;  1MIY A;  2VDB A;  3LU6 A;  4E99 A;  2QHB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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