2ABKA

Refinement of the native structure of endonuclease iii to a resolution of 1.85 angstrom
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
211
structure length
211
Chain Sequence
MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
pubmed rcsb
molecule tags Endonuclease
molecule keywords ENDONUCLEASE III
total genus 72
structure length 211
sequence length 211
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 1995-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2abkA01
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2abkA02
5CHZA 4B24A 4AIAA 4UNFA 2XHIA 1N3CA 1KG6A 2OFKA 1KG2A 2NOBA 1RRSA 3F10A 1WEIA 4EA4A 3I0WA 4OFHA 2H56A 2NOHA 1ORPA 1N39A 1HU0A 1FN7A 5AN4A 1YQKA 3N5NX 3FSPA 1DIZA 1VRLA 1P7MA 5KN8A 3KTUA 1KG7A 4B22A 1M3HA 2YG9A 1PU8A 2JHNA 1LWWA 1WEGA 3IHOA 4YOQA 4DK9A 1P59A 3CVSA 2JHJA 3OH9A 3CWTA 2NOFA 4OFAA 4EJYA 4EVVA 4EW4A 1N3AA 3I0XA 4B21A 1NKUA 4E9GA 1KG4A 1KG5A 4AI4A 2OFIA 1PU6A 3FHGA 1MUNA 2NOIA 1RRQA 4B23A 3F0ZA 4UOBA 2NOEA 5DPKA 1PVSA 3N0UA 1YQLA 1KO9A 1YQRA 1EBMA 4E9HA 4EJZA 1XQOA 1KEAA 4EA5A 3CWSA 4HSBA 4OFEA 2YG8A 3CW7A 1MPGA 1LWVA 3CWAA 1XG7A 1WEFA 1KQJA 1YQMA 2JG6A 1KG3A 3KNTA 3OGDA 3CVTA 3CWUA 4PIIA 2NOZA 3OH6A 1MUYA 1PU7A 1NGNA 4E9EA 1M3QA 3D4VA 3FHFA 1XQPA 5KN9A 3G0QA 4E9FA 4EW0A 3S6IA 2NOLA 4YPHA 1LMZA 3IH7A 2ABKA 1ORNA 1MUDA 4AI5A 2I5WA 1LWYA 4YPRA
chains in the Genus database with same CATH superfamily
5CHZA 4BDYA 4B24A 3L2UA 4AIAA 3OYCA 1U84A 4UNFA 2XHIA 4IKFA 1N3CA 1KG6A 2OFKA 1KG2A 2NOBA 1RRSA 3F10A 3S3MA 1WEIA 4EA4A 3I0WA 3OS2A 3L2WA 4OFHA 2W04A 3OYLA 3S3NA 2H56A 4E7KA 1ORPA 2NOHA 1N39A 3OYHA 1HU0A 1FN7A 5AN4A 1YQKA 3N5NX 4BDZA 3FSPA 1DIZA 1VRLA 1P7MA 3VW4A 5KN8A 3KTUA 1KG7A 3OYFA 4B22A 1M3HA 4ZTFA 2YG9A 4E7IA 1PU8A 2JHNA 1LWWA 1WEGA 3IHOA 3L2QA 4YOQA 4BE0A 4DK9A 3OYAA 3CVSA 1P59A 2JHJA 2W03A 3OH9A 3CWTA 4BE1A 4OFAA 2NOFA 4EJYA 3OYKA 4EVVA 4EW4A 1N3AA 3L2VA 3I0XA 4B21A 3OYBA 4E7JA 1NKUA 4E9GA 5FRNA 1KG4A 3OYNA 1KG5A 4AI4A 3OS1A 2OFIA 1PU6A 3OYEA 3FHGA 1MUNA 2NOIA 1RRQA 4B23A 4BE2A 3F0ZA 3NNQA 4UOBA 2NOEA 5DPKA 1PVSA 3N0UA 1YQLA 4E7HA 1KO9A 1YQRA 1EBMA 4E9HA 4EJZA 4ZTJA 1XQOA 1KEAA 4EA5A 3OS0A 3CWSA 4HSBA 4OFEA 3OY9A 2YG8A 3CW7A 1MPGA 1LWVA 3OYJA 3LCNA 3CWAA 1XG7A 1WEFA 2V75A 3OYMA 1KQJA 1YQMA 2JG6A 1KG3A 3KNTA 3L2RA 3OGDA 3CVTA 3CWUA 4PIIA 2NOZA 3OH6A 1MUYA 4NZGA 1PU7A 1NGNA 4E9EA 1M3QA 2JPSA 3OYDA 3D4VA 3OYGA 3FHFA 1XQPA 5KN9A 5FROA 3G0QA 3S3OA 4E7LA 4E9FA 4EW0A 3S6IA 2NOLA 4YPHA 1LMZA 3IH7A 2ABKA 3R2XC 1ORNA 1MUDA 4AI5A 2I5WA 1LWYA 5FRMA 4BACA 3OYIA 4YPRA
chains in the Genus database with same CATH topology
5CHZA 4B24A 4AIAA 4UNFA 2XHIA 1N3CA 1KG6A 2OFKA 1KG2A 2NOBA 1RRSA 3F10A 1WEIA 4EA4A 3I0WA 4OFHA 2H56A 2NOHA 1ORPA 1N39A 1HU0A 1FN7A 5AN4A 1YQKA 3N5NX 3FSPA 1DIZA 1VRLA 1P7MA 5KN8A 3KTUA 1KG7A 4B22A 1M3HA 2YG9A 1PU8A 2JHNA 1LWWA 1WEGA 3IHOA 4YOQA 4DK9A 1P59A 3CVSA 2JHJA 3OH9A 3CWTA 2NOFA 4OFAA 4EJYA 4EVVA 4EW4A 1N3AA 3I0XA 4B21A 1NKUA 4E9GA 1KG4A 1KG5A 4AI4A 2OFIA 1PU6A 3FHGA 1MUNA 2NOIA 1RRQA 4B23A 3F0ZA 4UOBA 2NOEA 5DPKA 1PVSA 3N0UA 1YQLA 1KO9A 1YQRA 1EBMA 4E9HA 4EJZA 1XQOA 1KEAA 4EA5A 3CWSA 4HSBA 4OFEA 2YG8A 3CW7A 1MPGA 1LWVA 3CWAA 1XG7A 1WEFA 1KQJA 1YQMA 2JG6A 1KG3A 3KNTA 3OGDA 3CVTA 3CWUA 4PIIA 2NOZA 3OH6A 1MUYA 1PU7A 1NGNA 4E9EA 1M3QA 3D4VA 3FHFA 1XQPA 5KN9A 3G0QA 4E9FA 4EW0A 3S6IA 2NOLA 4YPHA 1LMZA 3IH7A 2ABKA 1ORNA 1MUDA 4AI5A 2I5WA 1LWYA 4YPRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CHZ A;  4B24 A;  4AIA A;  4UNF A;  2XHI A;  1N3C A;  1KG6 A;  2OFK A;  1KG2 A;  2NOB A;  1RRS A;  3F10 A;  1WEI A;  4EA4 A;  3I0W A;  4OFH A;  2H56 A;  2NOH A;  1ORP A;  1N39 A;  1HU0 A;  1FN7 A;  5AN4 A;  1YQK A;  3N5N X;  3FSP A;  1DIZ A;  1VRL A;  1P7M A;  5KN8 A;  3KTU A;  1KG7 A;  4B22 A;  1M3H A;  2YG9 A;  1PU8 A;  2JHN A;  1LWW A;  1WEG A;  3IHO A;  4YOQ A;  4DK9 A;  1P59 A;  3CVS A;  2JHJ A;  3OH9 A;  3CWT A;  2NOF A;  4OFA A;  4EJY A;  4EVV A;  4EW4 A;  1N3A A;  3I0X A;  4B21 A;  1NKU A;  4E9G A;  1KG4 A;  1KG5 A;  4AI4 A;  2OFI A;  1PU6 A;  3FHG A;  1MUN A;  2NOI A;  1RRQ A;  4B23 A;  3F0Z A;  4UOB A;  2NOE A;  5DPK A;  1PVS A;  3N0U A;  1YQL A;  1KO9 A;  1YQR A;  1EBM A;  4E9H A;  4EJZ A;  1XQO A;  1KEA A;  4EA5 A;  3CWS A;  4HSB A;  4OFE A;  2YG8 A;  3CW7 A;  1MPG A;  1LWV A;  3CWA A;  1XG7 A;  1WEF A;  1KQJ A;  1YQM A;  2JG6 A;  1KG3 A;  3KNT A;  3OGD A;  3CVT A;  3CWU A;  4PII A;  2NOZ A;  3OH6 A;  1MUY A;  1PU7 A;  1NGN A;  4E9E A;  1M3Q A;  3D4V A;  3FHF A;  1XQP A;  5KN9 A;  3G0Q A;  4E9F A;  4EW0 A;  3S6I A;  2NOL A;  4YPH A;  1LMZ A;  3IH7 A;  2ABK A;  1ORN A;  1MUD A;  4AI5 A;  2I5W A;  1LWY A;  4YPR A; 
#chains in the Genus database with same CATH topology
 5CHZ A;  4BDY A;  4B24 A;  3L2U A;  4AIA A;  3OYC A;  1U84 A;  4UNF A;  2XHI A;  4IKF A;  1N3C A;  1KG6 A;  2OFK A;  1KG2 A;  2NOB A;  1RRS A;  3F10 A;  3S3M A;  1WEI A;  4EA4 A;  3I0W A;  3OS2 A;  3L2W A;  4OFH A;  2W04 A;  3OYL A;  3S3N A;  2H56 A;  4E7K A;  1ORP A;  2NOH A;  1N39 A;  3OYH A;  1HU0 A;  1FN7 A;  5AN4 A;  1YQK A;  3N5N X;  4BDZ A;  3FSP A;  1DIZ A;  1VRL A;  1P7M A;  3VW4 A;  5KN8 A;  3KTU A;  1KG7 A;  3OYF A;  4B22 A;  1M3H A;  4ZTF A;  2YG9 A;  4E7I A;  1PU8 A;  2JHN A;  1LWW A;  1WEG A;  3IHO A;  3L2Q A;  4YOQ A;  4BE0 A;  4DK9 A;  3OYA A;  3CVS A;  1P59 A;  2JHJ A;  2W03 A;  3OH9 A;  3CWT A;  4BE1 A;  4OFA A;  2NOF A;  4EJY A;  3OYK A;  4EVV A;  4EW4 A;  1N3A A;  3L2V A;  3I0X A;  4B21 A;  3OYB A;  4E7J A;  1NKU A;  4E9G A;  5FRN A;  1KG4 A;  3OYN A;  1KG5 A;  4AI4 A;  3OS1 A;  2OFI A;  1PU6 A;  3OYE A;  3FHG A;  1MUN A;  2NOI A;  1RRQ A;  4B23 A;  4BE2 A;  3F0Z A;  3NNQ A;  4UOB A;  2NOE A;  5DPK A;  1PVS A;  3N0U A;  1YQL A;  4E7H A;  1KO9 A;  1YQR A;  1EBM A;  4E9H A;  4EJZ A;  4ZTJ A;  1XQO A;  1KEA A;  4EA5 A;  3OS0 A;  3CWS A;  4HSB A;  4OFE A;  3OY9 A;  2YG8 A;  3CW7 A;  1MPG A;  1LWV A;  3OYJ A;  3LCN A;  3CWA A;  1XG7 A;  1WEF A;  2V75 A;  3OYM A;  1KQJ A;  1YQM A;  2JG6 A;  1KG3 A;  3KNT A;  3L2R A;  3OGD A;  3CVT A;  3CWU A;  4PII A;  2NOZ A;  3OH6 A;  1MUY A;  4NZG A;  1PU7 A;  1NGN A;  4E9E A;  1M3Q A;  2JPS A;  3OYD A;  3D4V A;  3OYG A;  3FHF A;  1XQP A;  5KN9 A;  5FRO A;  3G0Q A;  3S3O A;  4E7L A;  4E9F A;  4EW0 A;  3S6I A;  2NOL A;  4YPH A;  1LMZ A;  3IH7 A;  2ABK A;  3R2X C;  1ORN A;  1MUD A;  4AI5 A;  2I5W A;  1LWY A;  5FRM A;  4BAC A;  3OYI A;  4YPR A; 
#chains in the Genus database with same CATH homology
 5CHZ A;  4B24 A;  4AIA A;  4UNF A;  2XHI A;  1N3C A;  1KG6 A;  2OFK A;  1KG2 A;  2NOB A;  1RRS A;  3F10 A;  1WEI A;  4EA4 A;  3I0W A;  4OFH A;  2H56 A;  2NOH A;  1ORP A;  1N39 A;  1HU0 A;  1FN7 A;  5AN4 A;  1YQK A;  3N5N X;  3FSP A;  1DIZ A;  1VRL A;  1P7M A;  5KN8 A;  3KTU A;  1KG7 A;  4B22 A;  1M3H A;  2YG9 A;  1PU8 A;  2JHN A;  1LWW A;  1WEG A;  3IHO A;  4YOQ A;  4DK9 A;  1P59 A;  3CVS A;  2JHJ A;  3OH9 A;  3CWT A;  2NOF A;  4OFA A;  4EJY A;  4EVV A;  4EW4 A;  1N3A A;  3I0X A;  4B21 A;  1NKU A;  4E9G A;  1KG4 A;  1KG5 A;  4AI4 A;  2OFI A;  1PU6 A;  3FHG A;  1MUN A;  2NOI A;  1RRQ A;  4B23 A;  3F0Z A;  4UOB A;  2NOE A;  5DPK A;  1PVS A;  3N0U A;  1YQL A;  1KO9 A;  1YQR A;  1EBM A;  4E9H A;  4EJZ A;  1XQO A;  1KEA A;  4EA5 A;  3CWS A;  4HSB A;  4OFE A;  2YG8 A;  3CW7 A;  1MPG A;  1LWV A;  3CWA A;  1XG7 A;  1WEF A;  1KQJ A;  1YQM A;  2JG6 A;  1KG3 A;  3KNT A;  3OGD A;  3CVT A;  3CWU A;  4PII A;  2NOZ A;  3OH6 A;  1MUY A;  1PU7 A;  1NGN A;  4E9E A;  1M3Q A;  3D4V A;  3FHF A;  1XQP A;  5KN9 A;  3G0Q A;  4E9F A;  4EW0 A;  3S6I A;  2NOL A;  4YPH A;  1LMZ A;  3IH7 A;  2ABK A;  1ORN A;  1MUD A;  4AI5 A;  2I5W A;  1LWY A;  4YPR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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