2AGHB

Structural basis for cooperative transcription factor binding to the cbp coactivator
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
87
structure length
87
Chain Sequence
GVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Myb proto-oncogene protein
total genus 29
structure length 87
sequence length 87
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02172 KIX KIX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.20 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Coactivator CBP, KIX domain 2aghB00
2KWFA 2LXTA 2LQHA 4D7XA 1SB0A 2LQIA 2AGHB 2LXSA 1KDXA 2K0NA 2GUTA 4I9OA
chains in the Genus database with same CATH superfamily
4N3ZA 4E99A 4BY9C 4GDXA 3BPJA 3FNMA 4ZBQA 5GIOA 5ID7A 1E7EA 3KJLA 5IFOA 4HGMB 1MIWA 4PO0A 1GNJA 1J78A 1E7IA 4ZC6A 2LQIA 3H3AA 3M99C 2BXFA 4GDLB 2GUTA 2BXMA 3JRYA 4LA0A 2DG5A 2I30A 4IW2A 1N5UA 2NNWA 1E7AA 4LB9A 4K71A 4OTTA 3CX9A 2OT3A 1HA2A 2BXAA 4FJCB 2Z8KA 2BXIA 2QM6A 3FWCC 2E0YA 1MA9A 4Z69A 4IW1A 4ZBKA 2QMCA 2XVUA 4GDKB 4M70B 3W1SA 5IIHA 3B9MA 2BXDA 3A75A 2BXLA 3JQZA 2BXEA 2VDBA 3SIVB 4F5UA 2XVQA 4EMXA 4LB2A 2BXOA 1MUHA 5BPKA 4OTUA 1E7FA 1TF0A 2XMOA 5IJ5A 4DHXB 1E7CA 5GHKA 4G04A 3NVIA 3NVMA 2DBWA 1MUSA 2XW1A 4JK4A 4F5VA 1HK1A 4Z9OA 1NT2B 5B5TA 2BXGA 1KDXA 4W4UB 1O9XA 2DBXA 3LU6A 4LUFA 3WHQA 1JNBA 2ROHA 2LOQA 1LNSA 1VFIA 1HK5A 4G01A 2LXTA 2DYOA 2E0XA 1GNIA 2Z8IA 3FWBC 4F5TA 1HK3A 2KBZA 4OT2A 4GG2A 4K2CA 2EFHA 1TXUA 4TQ1A 4ZUXV 4BKEA 1MIYA 2LQHA 1H9ZA 1VZSA 5GINA 3LU8A 3SQJA 2CKXA 3B9LA 2EFEA 1BJ5A 3PLAA 4S1YA 1AO6A 3LU7A 4F5SA 4FK5B 1E7BA 4N0UD 4ZCGA 1E7HA 3WHSA 2VUEA 3SIUB 2BXQA 4I9OA 4DM0A 3G9KD 1BKEA 5HOZA 2EFCA 3UIVA 1SB0A 4L9QA 1KXPD 5DQFA 2OZBB 2BX8A 2XW0A 5IIUA 4WA6B 5D7GA 2DYMA 3V09A 4TQ0A 2BXBA 1IJGA 2VUFA 3A73A 2BXNA 2BXKA 1J7EA 2JUHA 4OR0A 3TDLA 4LUHA 4HGKA 3V08A 2BXCA 3MHSB 2QHBA 5ID9A 3GQUA 3V03A 3KIKA 4G03A 2XVVA 3H37A 3MHHB 1MIVA 2Z8JA 1BM0A 4FIPB 4J2VA 2V36A 2I2ZA 3NMUA 2BXHA 1FOUA 1E78A 3WHRA 3ICXA 1E7GA 2K0NA 1HK4A 2KWFA 2XVWA 4D7XA 5IJFA 3ECPA 5FUOA 4NAWB 2YDFA 2XSIA 3GA9L 1LOTA 2EFDA 3GQXA 3VQIA 4MBEC 1HK2A 4L8UA 5DBYA 5IIXA 1H5WA 2BXPA 4C31B 4ZBRA 4N0FD 1MM8A 1KW2A 2NQOA 3NVKA 2DBUA 5GIPA 2AGHB 2LXSA 1UORA 5IJEA 4L9KA 2AJEA
chains in the Genus database with same CATH topology
2KWFA 2LXTA 2LQHA 4D7XA 1SB0A 2LQIA 2AGHB 2LXSA 1KDXA 2K0NA 2GUTA 4I9OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KWF A;  2LXT A;  2LQH A;  4D7X A;  1SB0 A;  2LQI A;  2AGH B;  2LXS A;  1KDX A;  2K0N A;  2GUT A;  4I9O A; 
#chains in the Genus database with same CATH topology
 4N3Z A;  4E99 A;  4BY9 C;  4GDX A;  3BPJ A;  3FNM A;  4ZBQ A;  5GIO A;  5ID7 A;  1E7E A;  3KJL A;  5IFO A;  4HGM B;  1MIW A;  4PO0 A;  1GNJ A;  1J78 A;  1E7I A;  4ZC6 A;  2LQI A;  3H3A A;  3M99 C;  2BXF A;  4GDL B;  2GUT A;  2BXM A;  3JRY A;  4LA0 A;  2DG5 A;  2I30 A;  4IW2 A;  1N5U A;  2NNW A;  1E7A A;  4LB9 A;  4K71 A;  4OTT A;  3CX9 A;  2OT3 A;  1HA2 A;  2BXA A;  4FJC B;  2Z8K A;  2BXI A;  2QM6 A;  3FWC C;  2E0Y A;  1MA9 A;  4Z69 A;  4IW1 A;  4ZBK A;  2QMC A;  2XVU A;  4GDK B;  4M70 B;  3W1S A;  5IIH A;  3B9M A;  2BXD A;  3A75 A;  2BXL A;  3JQZ A;  2BXE A;  2VDB A;  3SIV B;  4F5U A;  2XVQ A;  4EMX A;  4LB2 A;  2BXO A;  1MUH A;  5BPK A;  4OTU A;  1E7F A;  1TF0 A;  2XMO A;  5IJ5 A;  4DHX B;  1E7C A;  5GHK A;  4G04 A;  3NVI A;  3NVM A;  2DBW A;  1MUS A;  2XW1 A;  4JK4 A;  4F5V A;  1HK1 A;  4Z9O A;  1NT2 B;  5B5T A;  2BXG A;  1KDX A;  4W4U B;  1O9X A;  2DBX A;  3LU6 A;  4LUF A;  3WHQ A;  1JNB A;  2ROH A;  2LOQ A;  1LNS A;  1VFI A;  1HK5 A;  4G01 A;  2LXT A;  2DYO A;  2E0X A;  1GNI A;  2Z8I A;  3FWB C;  4F5T A;  1HK3 A;  2KBZ A;  4OT2 A;  4GG2 A;  4K2C A;  2EFH A;  1TXU A;  4TQ1 A;  4ZUX V;  4BKE A;  1MIY A;  2LQH A;  1H9Z A;  1VZS A;  5GIN A;  3LU8 A;  3SQJ A;  2CKX A;  3B9L A;  2EFE A;  1BJ5 A;  3PLA A;  4S1Y A;  1AO6 A;  3LU7 A;  4F5S A;  4FK5 B;  1E7B A;  4N0U D;  4ZCG A;  1E7H A;  3WHS A;  2VUE A;  3SIU B;  2BXQ A;  4I9O A;  4DM0 A;  3G9K D;  1BKE A;  5HOZ A;  2EFC A;  3UIV A;  1SB0 A;  4L9Q A;  1KXP D;  5DQF A;  2OZB B;  2BX8 A;  2XW0 A;  5IIU A;  4WA6 B;  5D7G A;  2DYM A;  3V09 A;  4TQ0 A;  2BXB A;  1IJG A;  2VUF A;  3A73 A;  2BXN A;  2BXK A;  1J7E A;  2JUH A;  4OR0 A;  3TDL A;  4LUH A;  4HGK A;  3V08 A;  2BXC A;  3MHS B;  2QHB A;  5ID9 A;  3GQU A;  3V03 A;  3KIK A;  4G03 A;  2XVV A;  3H37 A;  3MHH B;  1MIV A;  2Z8J A;  1BM0 A;  4FIP B;  4J2V A;  2V36 A;  2I2Z A;  3NMU A;  2BXH A;  1FOU A;  1E78 A;  3WHR A;  3ICX A;  1E7G A;  2K0N A;  1HK4 A;  2KWF A;  2XVW A;  4D7X A;  5IJF A;  3ECP A;  5FUO A;  4NAW B;  2YDF A;  2XSI A;  3GA9 L;  1LOT A;  2EFD A;  3GQX A;  3VQI A;  4MBE C;  1HK2 A;  4L8U A;  5DBY A;  5IIX A;  1H5W A;  2BXP A;  4C31 B;  4ZBR A;  4N0F D;  1MM8 A;  1KW2 A;  2NQO A;  3NVK A;  2DBU A;  5GIP A;  2AGH B;  2LXS A;  1UOR A;  5IJE A;  4L9K A;  2AJE A; 
#chains in the Genus database with same CATH homology
 2KWF A;  2LXT A;  2LQH A;  4D7X A;  1SB0 A;  2LQI A;  2AGH B;  2LXS A;  1KDX A;  2K0N A;  2GUT A;  4I9O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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