2BXAA

Human serum albumin complexed with 3-carboxy-4-methyl-5-propyl-2- furanpropanoic acid (cmpf)
Total Genus 219
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
219
sequence length
578
structure length
569
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 219
structure length 569
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxaA05
1E7AA 5IIHA 4HGMB 1HK5A 3LU7A 4N0UD 2VUEA 4Z69A 5IIUA 2XVVA 5ID9A 1E7EA 4OR0A 4IW2A 2I2ZA 1E7GA 4E99A 5DQFA 3V03A 5FUOA 1GNIA 4G04A 2BXKA 3A73A 3LU6A 4PO0A 3TDLA 1E7CA 4LUFA 1J78A 1BKEA 3JQZA 3LU8A 1N5UA 3B9LA 2XVQA 1HK3A 4F5VA 4JK4A 4ZBQA 4N0FD 2BXDA 5IJFA 2BXAA 4BKEA 2XSIA 3JRYA 2XVWA 4F5UA 2XW1A 4J2VA 2BXPA 3V08A 4LUHA 4EMXA 1E78A 1KXPD 1HK1A 4LA0A 2XVUA 2I30A 4L8UA 2BXQA 1BM0A 1GNJA 1O9XA 3SQJA 4F5TA 4F5SA 1MA9A 1AO6A 4K2CA 4OT2A 1HK4A 5HOZA 4LB9A 5GHKA 3UIVA 1HA2A 4K71A 2BXFA 1E7HA 2BXBA 4G03A 4L9KA 1BJ5A 2VUFA 2YDFA 1E7FA 1HK2A 3B9MA 5IIXA 1TF0A 2BXNA 2BXGA 5IJ5A 2VDBA 2XW0A 2BXMA 1J7EA 1KW2A 2BXLA 5DBYA 2BXEA 5ID7A 3CX9A 2BXCA 1E7BA 5IJEA 2BX8A 4L9QA 1H9ZA 1UORA 1LOTA 4S1YA 2BXOA 2BXHA 4HGKA 3V09A 1E7IA 4LB2A 4IW1A 4ZBRA 5IFOA 2BXIA
chains in the Genus database with same CATH superfamily
2CKXA 1E7AA 5IIHA 4M70B 2LXSA 2DYMA 4HGMB 1JNBA 1KDXA 1HK5A 2EFHA 3LU7A 1IJGA 2VUEA 4N0UD 4ZBKA 2Z8JA 2EFDA 2Z8KA 4Z69A 2XVVA 5IIUA 3WHQA 5ID9A 2K0NA 1E7EA 4OR0A 4MBEC 4IW2A 3NVMA 2I2ZA 1E7GA 4E99A 2LQIA 5DQFA 3V03A 5BPKA 5FUOA 2DBWA 1GNIA 3NVKA 4G04A 2BXKA 3PLAA 3A73A 3LU6A 4PO0A 2JUHA 3TDLA 5D7GA 3ECPA 1E7CA 4LUFA 1J78A 1H5WA 1BKEA 2ROHA 3BPJA 3JQZA 4I9OA 3LU8A 4N3ZA 3W1SA 1N5UA 5GINA 4GDXA 3B9LA 2E0YA 1TXUA 3KIKA 2DG5A 2LQHA 2XVQA 4OTTA 4GDKB 1HK3A 4F5VA 4DM0A 4BY9C 2DBUA 4JK4A 4W4UB 4N0FD 4ZBQA 2KBZA 2V36A 3MHHB 2BXDA 2LXTA 2BXAA 2EFEA 2XSIA 4BKEA 5IJFA 3G9KD 2XVWA 3JRYA 4F5UA 2XW1A 3KJLA 4FJCB 4NAWB 2QHBA 4J2VA 4ZC6A 2BXPA 1SB0A 4LUHA 3V08A 4EMXA 1E78A 3FWBC 1KXPD 1HK1A 4LA0A 2XVUA 2I30A 3FNMA 4L8UA 3WHSA 4OTUA 3SIUB 3VQIA 4C31B 2BXQA 1BM0A 1GNJA 5B5TA 3GQUA 2AJEA 1O9XA 2GUTA 3SQJA 4F5TA 2DBXA 2KWFA 1MM8A 4F5SA 3NVIA 1MA9A 1MIVA 1AO6A 4K2CA 4OT2A 4TQ0A 1HK4A 5GIOA 3MHSB 2DYOA 1MUSA 5HOZA 3GQXA 4LB9A 4G01A 5GHKA 3UIVA 1HA2A 2NQOA 4K71A 3M99C 2BXFA 4Z9OA 1E7HA 2BXBA 3A75A 4G03A 1MIWA 1BJ5A 2VUFA 1VZSA 4L9KA 2YDFA 1E7FA 4FIPB 1HK2A 3B9MA 5IIXA 3H37A 3WHRA 4GG2A 1TF0A 3SIVB 2BXNA 2BXGA 2Z8IA 5IJ5A 4ZCGA 4TQ1A 2VDBA 1MIYA 1NT2B 2XW0A 2BXMA 2OT3A 1J7EA 1KW2A 3H3AA 2BXLA 2QMCA 2LOQA 2BXEA 2QM6A 5DBYA 4DHXB 5ID7A 3CX9A 4FK5B 2BXCA 1E7BA 1VFIA 2OZBB 5IJEA 2BX8A 2E0XA 2XMOA 2AGHB 4L9QA 1H9ZA 4ZUXV 1LNSA 1UORA 1LOTA 3FWCC 4S1YA 2BXOA 3GA9L 2BXHA 4HGKA 3V09A 4GDLB 1E7IA 2EFCA 1MUHA 2NNWA 4WA6B 3NMUA 4LB2A 5GIPA 4IW1A 3ICXA 4ZBRA 5IFOA 4D7XA 2BXIA 1FOUA
chains in the Genus database with same CATH topology
2CKXA 1E7AA 5IIHA 4M70B 2DYMA 4HGMB 1JNBA 1HK5A 2EFHA 3LU7A 1IJGA 2VUEA 4N0UD 4ZBKA 2Z8JA 2EFDA 2Z8KA 4Z69A 2XVVA 5IIUA 3WHQA 5ID9A 1E7EA 4OR0A 4MBEC 4IW2A 3NVMA 2I2ZA 1E7GA 4E99A 5BPKA 5DQFA 3V03A 5FUOA 2DBWA 1GNIA 3NVKA 4G04A 2BXKA 3PLAA 3A73A 3LU6A 4PO0A 2JUHA 3TDLA 5D7GA 1E7CA 4LUFA 1J78A 1H5WA 1BKEA 2ROHA 3JQZA 3LU8A 4N3ZA 3W1SA 1N5UA 5GINA 4GDXA 3B9LA 2E0YA 1TXUA 3KIKA 2DG5A 2XVQA 4OTTA 4GDKB 1HK3A 4F5VA 4BY9C 2DBUA 4JK4A 4W4UB 4N0FD 4ZBQA 2KBZA 2V36A 3MHHB 2BXDA 5IJFA 2BXAA 2EFEA 2XSIA 4BKEA 3G9KD 2XVWA 3JRYA 4F5UA 2XW1A 3KJLA 4FJCB 4NAWB 2QHBA 4J2VA 4ZC6A 2BXPA 3V08A 4LUHA 4EMXA 1E78A 3FWBC 1KXPD 1HK1A 4LA0A 2XVUA 2I30A 3FNMA 4L8UA 3WHSA 4OTUA 3SIUB 3VQIA 4C31B 2BXQA 1BM0A 1GNJA 5B5TA 3GQUA 2AJEA 1O9XA 3SQJA 4F5TA 2DBXA 3NVIA 4F5SA 1MA9A 1MIVA 1AO6A 4K2CA 4OT2A 4TQ0A 1HK4A 5GIOA 3MHSB 2DYOA 5HOZA 3GQXA 4LB9A 4G01A 5GHKA 3UIVA 1HA2A 2NQOA 4K71A 3M99C 2BXFA 4Z9OA 1E7HA 2BXBA 3A75A 4G03A 1MIWA 1BJ5A 2VUFA 1VZSA 4L9KA 2YDFA 1E7FA 4FIPB 1HK2A 3B9MA 5IIXA 3H37A 3WHRA 4GG2A 1TF0A 3SIVB 2BXNA 2BXGA 2Z8IA 5IJ5A 4ZCGA 4TQ1A 2VDBA 1MIYA 1NT2B 2XW0A 2BXMA 2OT3A 1J7EA 1KW2A 3H3AA 2BXLA 2QMCA 2LOQA 2BXEA 2QM6A 5DBYA 4DHXB 5ID7A 3CX9A 4FK5B 2BXCA 1E7BA 1VFIA 2OZBB 5IJEA 2BX8A 2E0XA 2XMOA 4L9QA 4ZUXV 1H9ZA 1LNSA 1UORA 1LOTA 3FWCC 4S1YA 2BXOA 3GA9L 2BXHA 4HGKA 3V09A 4GDLB 1E7IA 2EFCA 2NNWA 4WA6B 3NMUA 4LB2A 5GIPA 4IW1A 3ICXA 4ZBRA 5IFOA 2BXIA 1FOUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E7A A;  5IIH A;  4HGM B;  1HK5 A;  3LU7 A;  4N0U D;  2VUE A;  4Z69 A;  5IIU A;  2XVV A;  5ID9 A;  1E7E A;  4OR0 A;  4IW2 A;  2I2Z A;  1E7G A;  4E99 A;  5DQF A;  3V03 A;  5FUO A;  1GNI A;  4G04 A;  2BXK A;  3A73 A;  3LU6 A;  4PO0 A;  3TDL A;  1E7C A;  4LUF A;  1J78 A;  1BKE A;  3JQZ A;  3LU8 A;  1N5U A;  3B9L A;  2XVQ A;  1HK3 A;  4F5V A;  4JK4 A;  4ZBQ A;  4N0F D;  2BXD A;  5IJF A;  2BXA A;  4BKE A;  2XSI A;  3JRY A;  2XVW A;  4F5U A;  2XW1 A;  4J2V A;  2BXP A;  3V08 A;  4LUH A;  4EMX A;  1E78 A;  1KXP D;  1HK1 A;  4LA0 A;  2XVU A;  2I30 A;  4L8U A;  2BXQ A;  1BM0 A;  1GNJ A;  1O9X A;  3SQJ A;  4F5T A;  4F5S A;  1MA9 A;  1AO6 A;  4K2C A;  4OT2 A;  1HK4 A;  5HOZ A;  4LB9 A;  5GHK A;  3UIV A;  1HA2 A;  4K71 A;  2BXF A;  1E7H A;  2BXB A;  4G03 A;  4L9K A;  1BJ5 A;  2VUF A;  2YDF A;  1E7F A;  1HK2 A;  3B9M A;  5IIX A;  1TF0 A;  2BXN A;  2BXG A;  5IJ5 A;  2VDB A;  2XW0 A;  2BXM A;  1J7E A;  1KW2 A;  2BXL A;  5DBY A;  2BXE A;  5ID7 A;  3CX9 A;  2BXC A;  1E7B A;  5IJE A;  2BX8 A;  4L9Q A;  1H9Z A;  1UOR A;  1LOT A;  4S1Y A;  2BXO A;  2BXH A;  4HGK A;  3V09 A;  1E7I A;  4LB2 A;  4IW1 A;  4ZBR A;  5IFO A;  2BXI A; 
#chains in the Genus database with same CATH topology
 2CKX A;  1E7A A;  5IIH A;  4M70 B;  2LXS A;  2DYM A;  4HGM B;  1JNB A;  1KDX A;  1HK5 A;  2EFH A;  3LU7 A;  1IJG A;  2VUE A;  4N0U D;  4ZBK A;  2Z8J A;  2EFD A;  2Z8K A;  4Z69 A;  2XVV A;  5IIU A;  3WHQ A;  5ID9 A;  2K0N A;  1E7E A;  4OR0 A;  4MBE C;  4IW2 A;  3NVM A;  2I2Z A;  1E7G A;  4E99 A;  2LQI A;  5DQF A;  3V03 A;  5BPK A;  5FUO A;  2DBW A;  1GNI A;  3NVK A;  4G04 A;  2BXK A;  3PLA A;  3A73 A;  3LU6 A;  4PO0 A;  2JUH A;  3TDL A;  5D7G A;  3ECP A;  1E7C A;  4LUF A;  1J78 A;  1H5W A;  1BKE A;  2ROH A;  3BPJ A;  3JQZ A;  4I9O A;  3LU8 A;  4N3Z A;  3W1S A;  1N5U A;  5GIN A;  4GDX A;  3B9L A;  2E0Y A;  1TXU A;  3KIK A;  2DG5 A;  2LQH A;  2XVQ A;  4OTT A;  4GDK B;  1HK3 A;  4F5V A;  4DM0 A;  4BY9 C;  2DBU A;  4JK4 A;  4W4U B;  4N0F D;  4ZBQ A;  2KBZ A;  2V36 A;  3MHH B;  2BXD A;  2LXT A;  2BXA A;  2EFE A;  2XSI A;  4BKE A;  5IJF A;  3G9K D;  2XVW A;  3JRY A;  4F5U A;  2XW1 A;  3KJL A;  4FJC B;  4NAW B;  2QHB A;  4J2V A;  4ZC6 A;  2BXP A;  1SB0 A;  4LUH A;  3V08 A;  4EMX A;  1E78 A;  3FWB C;  1KXP D;  1HK1 A;  4LA0 A;  2XVU A;  2I30 A;  3FNM A;  4L8U A;  3WHS A;  4OTU A;  3SIU B;  3VQI A;  4C31 B;  2BXQ A;  1BM0 A;  1GNJ A;  5B5T A;  3GQU A;  2AJE A;  1O9X A;  2GUT A;  3SQJ A;  4F5T A;  2DBX A;  2KWF A;  1MM8 A;  4F5S A;  3NVI A;  1MA9 A;  1MIV A;  1AO6 A;  4K2C A;  4OT2 A;  4TQ0 A;  1HK4 A;  5GIO A;  3MHS B;  2DYO A;  1MUS A;  5HOZ A;  3GQX A;  4LB9 A;  4G01 A;  5GHK A;  3UIV A;  1HA2 A;  2NQO A;  4K71 A;  3M99 C;  2BXF A;  4Z9O A;  1E7H A;  2BXB A;  3A75 A;  4G03 A;  1MIW A;  1BJ5 A;  2VUF A;  1VZS A;  4L9K A;  2YDF A;  1E7F A;  4FIP B;  1HK2 A;  3B9M A;  5IIX A;  3H37 A;  3WHR A;  4GG2 A;  1TF0 A;  3SIV B;  2BXN A;  2BXG A;  2Z8I A;  5IJ5 A;  4ZCG A;  4TQ1 A;  2VDB A;  1MIY A;  1NT2 B;  2XW0 A;  2BXM A;  2OT3 A;  1J7E A;  1KW2 A;  3H3A A;  2BXL A;  2QMC A;  2LOQ A;  2BXE A;  2QM6 A;  5DBY A;  4DHX B;  5ID7 A;  3CX9 A;  4FK5 B;  2BXC A;  1E7B A;  1VFI A;  2OZB B;  5IJE A;  2BX8 A;  2E0X A;  2XMO A;  2AGH B;  4L9Q A;  1H9Z A;  4ZUX V;  1LNS A;  1UOR A;  1LOT A;  3FWC C;  4S1Y A;  2BXO A;  3GA9 L;  2BXH A;  4HGK A;  3V09 A;  4GDL B;  1E7I A;  2EFC A;  1MUH A;  2NNW A;  4WA6 B;  3NMU A;  4LB2 A;  5GIP A;  4IW1 A;  3ICX A;  4ZBR A;  5IFO A;  4D7X A;  2BXI A;  1FOU A; 
#chains in the Genus database with same CATH homology
 2CKX A;  1E7A A;  5IIH A;  4M70 B;  2DYM A;  4HGM B;  1JNB A;  1HK5 A;  2EFH A;  3LU7 A;  1IJG A;  2VUE A;  4N0U D;  4ZBK A;  2Z8J A;  2EFD A;  2Z8K A;  4Z69 A;  2XVV A;  5IIU A;  3WHQ A;  5ID9 A;  1E7E A;  4OR0 A;  4MBE C;  4IW2 A;  3NVM A;  2I2Z A;  1E7G A;  4E99 A;  5BPK A;  5DQF A;  3V03 A;  5FUO A;  2DBW A;  1GNI A;  3NVK A;  4G04 A;  2BXK A;  3PLA A;  3A73 A;  3LU6 A;  4PO0 A;  2JUH A;  3TDL A;  5D7G A;  1E7C A;  4LUF A;  1J78 A;  1H5W A;  1BKE A;  2ROH A;  3JQZ A;  3LU8 A;  4N3Z A;  3W1S A;  1N5U A;  5GIN A;  4GDX A;  3B9L A;  2E0Y A;  1TXU A;  3KIK A;  2DG5 A;  2XVQ A;  4OTT A;  4GDK B;  1HK3 A;  4F5V A;  4BY9 C;  2DBU A;  4JK4 A;  4W4U B;  4N0F D;  4ZBQ A;  2KBZ A;  2V36 A;  3MHH B;  2BXD A;  5IJF A;  2BXA A;  2EFE A;  2XSI A;  4BKE A;  3G9K D;  2XVW A;  3JRY A;  4F5U A;  2XW1 A;  3KJL A;  4FJC B;  4NAW B;  2QHB A;  4J2V A;  4ZC6 A;  2BXP A;  3V08 A;  4LUH A;  4EMX A;  1E78 A;  3FWB C;  1KXP D;  1HK1 A;  4LA0 A;  2XVU A;  2I30 A;  3FNM A;  4L8U A;  3WHS A;  4OTU A;  3SIU B;  3VQI A;  4C31 B;  2BXQ A;  1BM0 A;  1GNJ A;  5B5T A;  3GQU A;  2AJE A;  1O9X A;  3SQJ A;  4F5T A;  2DBX A;  3NVI A;  4F5S A;  1MA9 A;  1MIV A;  1AO6 A;  4K2C A;  4OT2 A;  4TQ0 A;  1HK4 A;  5GIO A;  3MHS B;  2DYO A;  5HOZ A;  3GQX A;  4LB9 A;  4G01 A;  5GHK A;  3UIV A;  1HA2 A;  2NQO A;  4K71 A;  3M99 C;  2BXF A;  4Z9O A;  1E7H A;  2BXB A;  3A75 A;  4G03 A;  1MIW A;  1BJ5 A;  2VUF A;  1VZS A;  4L9K A;  2YDF A;  1E7F A;  4FIP B;  1HK2 A;  3B9M A;  5IIX A;  3H37 A;  3WHR A;  4GG2 A;  1TF0 A;  3SIV B;  2BXN A;  2BXG A;  2Z8I A;  5IJ5 A;  4ZCG A;  4TQ1 A;  2VDB A;  1MIY A;  1NT2 B;  2XW0 A;  2BXM A;  2OT3 A;  1J7E A;  1KW2 A;  3H3A A;  2BXL A;  2QMC A;  2LOQ A;  2BXE A;  2QM6 A;  5DBY A;  4DHX B;  5ID7 A;  3CX9 A;  4FK5 B;  2BXC A;  1E7B A;  1VFI A;  2OZB B;  5IJE A;  2BX8 A;  2E0X A;  2XMO A;  4L9Q A;  4ZUX V;  1H9Z A;  1LNS A;  1UOR A;  1LOT A;  3FWC C;  4S1Y A;  2BXO A;  3GA9 L;  2BXH A;  4HGK A;  3V09 A;  4GDL B;  1E7I A;  2EFC A;  2NNW A;  4WA6 B;  3NMU A;  4LB2 A;  5GIP A;  4IW1 A;  3ICX A;  4ZBR A;  5IFO A;  2BXI A;  1FOU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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