2BXBA

Human serum albumin complexed with oxyphenbutazone
Total Genus 197
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
197
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 197
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxbA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxbA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxbA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxbA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxbA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxbA05
1E7FA 1E7IA 4G03A 4LB9A 4EMXA 2BXPA 2YDFA 1E7EA 1BM0A 1UORA 5IJEA 4OR0A 4LB2A 4F5VA 1BKEA 2BXEA 2BXKA 4LA0A 4N0UD 2BXNA 5ID7A 5ID9A 1KXPD 5IIUA 4L8UA 5IIHA 1LOTA 5DBYA 4HGKA 2XW0A 4F5UA 1TF0A 1GNJA 1E78A 4LUHA 3A73A 2BXQA 2BXBA 5IJFA 2BXMA 3JRYA 4L9QA 3UIVA 5IFOA 1E7BA 2BXHA 4LUFA 1HK5A 2VUFA 1BJ5A 3B9MA 4L9KA 4HGMB 3V09A 1E7AA 3JQZA 1HK1A 2BXIA 3V03A 2XVVA 2BXAA 4J2VA 4PO0A 4OT2A 2XW1A 4F5SA 3CX9A 4Z69A 4G04A 4ZBRA 5IJ5A 5IIXA 2BXFA 2BXLA 2BXDA 1MA9A 2VUEA 3LU6A 2I2ZA 3TDLA 4IW1A 3V08A 2BXCA 1J78A 2XSIA 4S1YA 1E7GA 1HK2A 2VDBA 4N0FD 1E7HA 5DQFA 5HOZA 2XVQA 1E7CA 4BKEA 3LU8A 1O9XA 4K71A 1HA2A 1H9ZA 3B9LA 1AO6A 3LU7A 2BX8A 1KW2A 1GNIA 4E99A 1HK4A 2BXOA 2XVWA 4ZBQA 1N5UA 4JK4A 1HK3A 3SQJA 5GHKA 4K2CA 1J7EA 4IW2A 2BXGA 2I30A 4F5TA 5FUOA 2XVUA
chains in the Genus database with same CATH superfamily
2QMCA 4FJCB 1E7FA 5B5TA 4FIPB 1E7IA 2LQHA 4G03A 4LB9A 3WHSA 2Z8KA 1FOUA 3G9KD 4EMXA 2QHBA 2BXPA 5GIPA 2NNWA 2YDFA 1E7EA 1BM0A 1IJGA 1UORA 2DYMA 4ZCGA 4OR0A 5IJEA 2ROHA 2EFHA 2EFDA 4TQ0A 4W4UB 4LB2A 1NT2B 1VZSA 4Z9OA 4F5VA 3FNMA 3H3AA 3SIVB 3KJLA 1BKEA 3GQUA 2BXEA 4OTTA 3VQIA 2LQIA 1MUHA 3KIKA 2BXKA 4I9OA 4LA0A 4N0UD 5D7GA 2Z8JA 2BXNA 5ID7A 5ID9A 1KXPD 5IIUA 4L8UA 3WHQA 1LOTA 3A75A 5IIHA 5DBYA 4WA6B 4DHXB 1KDXA 2NQOA 4HGKA 2XW0A 3NVKA 4F5UA 1TF0A 1GNJA 1E78A 2OZBB 2LXSA 3A73A 4LUHA 1MIWA 2BXQA 2BXBA 4DM0A 3NVIA 5IJFA 2BXMA 3JRYA 4L9QA 3UIVA 5IFOA 2OT3A 2AJEA 4ZC6A 1E7BA 2BXHA 3FWCC 4LUFA 5GINA 1HK5A 1MIYA 3GA9L 2VUFA 2EFCA 1BJ5A 3B9MA 4L9KA 4ZBKA 3ECPA 4HGMB 4TQ1A 1H5WA 2DBWA 4OTUA 3V09A 1E7AA 3JQZA 1HK1A 2DBUA 2BXIA 3H37A 2GUTA 4NAWB 3V03A 5BPKA 2KWFA 2XVVA 2BXAA 4GDLB 3M99C 4J2VA 4PO0A 3NVMA 4OT2A 3PLAA 2E0YA 1JNBA 2XW1A 4F5SA 3CX9A 4GDKB 3SIUB 4Z69A 4G04A 4ZBRA 5IJ5A 2KBZA 3WHRA 5IIXA 2LOQA 3FWBC 4ZUXV 2BXFA 2E0XA 2BXLA 4G01A 3W1SA 2BXDA 2DBXA 2K0NA 1MA9A 1LNSA 2VUEA 2QM6A 2XMOA 3LU6A 2I2ZA 3TDLA 4IW1A 1SB0A 3V08A 2BXCA 1J78A 2XSIA 2DYOA 4S1YA 4BY9C 1MM8A 2Z8IA 1E7GA 1HK2A 2VDBA 2LXTA 2AGHB 4N0FD 1E7HA 5DQFA 5HOZA 2XVQA 4GG2A 1E7CA 3BPJA 3LU8A 4BKEA 2DG5A 1O9XA 4K71A 3MHSB 1MUSA 1HA2A 1H9ZA 3B9LA 3GQXA 2EFEA 2JUHA 1AO6A 3LU7A 2BX8A 1KW2A 1GNIA 4E99A 1HK4A 2BXOA 3MHHB 4C31B 1TXUA 3NMUA 2XVWA 4ZBQA 4D7XA 1N5UA 4GDXA 4JK4A 1MIVA 1HK3A 3SQJA 5GHKA 4FK5B 4K2CA 1J7EA 4M70B 3ICXA 2V36A 1VFIA 4IW2A 2BXGA 2I30A 4N3ZA 4F5TA 5GIOA 5FUOA 4MBEC 2CKXA 2XVUA
chains in the Genus database with same CATH topology
2QMCA 4FJCB 1E7FA 5B5TA 4FIPB 1E7IA 4G03A 4LB9A 3WHSA 2Z8KA 1FOUA 3G9KD 4EMXA 2QHBA 2BXPA 5GIPA 2NNWA 2YDFA 1E7EA 1BM0A 1IJGA 1UORA 2DYMA 4ZCGA 4OR0A 5IJEA 2ROHA 2EFHA 2EFDA 4TQ0A 4W4UB 4LB2A 1NT2B 1VZSA 4Z9OA 4F5VA 3FNMA 3H3AA 3SIVB 3KJLA 1BKEA 3GQUA 2BXEA 4OTTA 3VQIA 3KIKA 2BXKA 4LA0A 4N0UD 5D7GA 2Z8JA 2BXNA 5ID7A 5ID9A 1KXPD 5IIUA 4L8UA 3WHQA 1LOTA 3A75A 5IIHA 5DBYA 4WA6B 4DHXB 2NQOA 4HGKA 2XW0A 3NVKA 4F5UA 1TF0A 1GNJA 1E78A 2OZBB 4LUHA 3A73A 1MIWA 2BXQA 2BXBA 3NVIA 5IJFA 2BXMA 3JRYA 4L9QA 3UIVA 5IFOA 2OT3A 2AJEA 4ZC6A 1E7BA 2BXHA 3FWCC 4LUFA 5GINA 1HK5A 1MIYA 3GA9L 2VUFA 2EFCA 1BJ5A 3B9MA 4L9KA 4ZBKA 4HGMB 4TQ1A 1H5WA 2DBWA 4OTUA 3V09A 1E7AA 3JQZA 1HK1A 2DBUA 2BXIA 3H37A 5BPKA 4NAWB 3V03A 2XVVA 2BXAA 4GDLB 3M99C 4J2VA 4PO0A 3NVMA 4OT2A 3PLAA 2E0YA 1JNBA 2XW1A 4F5SA 3CX9A 4GDKB 3SIUB 4Z69A 4G04A 4ZBRA 5IJ5A 2KBZA 3WHRA 5IIXA 2LOQA 3FWBC 4ZUXV 2BXFA 2E0XA 2BXLA 4G01A 3W1SA 2BXDA 2DBXA 1MA9A 1LNSA 2VUEA 2QM6A 2XMOA 3LU6A 2I2ZA 3TDLA 4IW1A 3V08A 2BXCA 1J78A 2XSIA 2DYOA 4S1YA 4BY9C 2Z8IA 1E7GA 1HK2A 2VDBA 4N0FD 1E7HA 5DQFA 5HOZA 2XVQA 4GG2A 1E7CA 4BKEA 3LU8A 2DG5A 1O9XA 4K71A 3MHSB 1HA2A 1H9ZA 3B9LA 3GQXA 2EFEA 2JUHA 1AO6A 3LU7A 2BX8A 1KW2A 1GNIA 4E99A 1HK4A 2BXOA 3MHHB 4C31B 1TXUA 3NMUA 2XVWA 4ZBQA 1N5UA 4GDXA 4JK4A 1MIVA 1HK3A 3SQJA 5GHKA 4FK5B 4K2CA 1J7EA 4M70B 3ICXA 2V36A 1VFIA 4IW2A 2BXGA 2I30A 4N3ZA 4F5TA 5GIOA 5FUOA 4MBEC 2CKXA 2XVUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E7F A;  1E7I A;  4G03 A;  4LB9 A;  4EMX A;  2BXP A;  2YDF A;  1E7E A;  1BM0 A;  1UOR A;  5IJE A;  4OR0 A;  4LB2 A;  4F5V A;  1BKE A;  2BXE A;  2BXK A;  4LA0 A;  4N0U D;  2BXN A;  5ID7 A;  5ID9 A;  1KXP D;  5IIU A;  4L8U A;  5IIH A;  1LOT A;  5DBY A;  4HGK A;  2XW0 A;  4F5U A;  1TF0 A;  1GNJ A;  1E78 A;  4LUH A;  3A73 A;  2BXQ A;  2BXB A;  5IJF A;  2BXM A;  3JRY A;  4L9Q A;  3UIV A;  5IFO A;  1E7B A;  2BXH A;  4LUF A;  1HK5 A;  2VUF A;  1BJ5 A;  3B9M A;  4L9K A;  4HGM B;  3V09 A;  1E7A A;  3JQZ A;  1HK1 A;  2BXI A;  3V03 A;  2XVV A;  2BXA A;  4J2V A;  4PO0 A;  4OT2 A;  2XW1 A;  4F5S A;  3CX9 A;  4Z69 A;  4G04 A;  4ZBR A;  5IJ5 A;  5IIX A;  2BXF A;  2BXL A;  2BXD A;  1MA9 A;  2VUE A;  3LU6 A;  2I2Z A;  3TDL A;  4IW1 A;  3V08 A;  2BXC A;  1J78 A;  2XSI A;  4S1Y A;  1E7G A;  1HK2 A;  2VDB A;  4N0F D;  1E7H A;  5DQF A;  5HOZ A;  2XVQ A;  1E7C A;  4BKE A;  3LU8 A;  1O9X A;  4K71 A;  1HA2 A;  1H9Z A;  3B9L A;  1AO6 A;  3LU7 A;  2BX8 A;  1KW2 A;  1GNI A;  4E99 A;  1HK4 A;  2BXO A;  2XVW A;  4ZBQ A;  1N5U A;  4JK4 A;  1HK3 A;  3SQJ A;  5GHK A;  4K2C A;  1J7E A;  4IW2 A;  2BXG A;  2I30 A;  4F5T A;  5FUO A;  2XVU A; 
#chains in the Genus database with same CATH topology
 2QMC A;  4FJC B;  1E7F A;  5B5T A;  4FIP B;  1E7I A;  2LQH A;  4G03 A;  4LB9 A;  3WHS A;  2Z8K A;  1FOU A;  3G9K D;  4EMX A;  2QHB A;  2BXP A;  5GIP A;  2NNW A;  2YDF A;  1E7E A;  1BM0 A;  1IJG A;  1UOR A;  2DYM A;  4ZCG A;  4OR0 A;  5IJE A;  2ROH A;  2EFH A;  2EFD A;  4TQ0 A;  4W4U B;  4LB2 A;  1NT2 B;  1VZS A;  4Z9O A;  4F5V A;  3FNM A;  3H3A A;  3SIV B;  3KJL A;  1BKE A;  3GQU A;  2BXE A;  4OTT A;  3VQI A;  2LQI A;  1MUH A;  3KIK A;  2BXK A;  4I9O A;  4LA0 A;  4N0U D;  5D7G A;  2Z8J A;  2BXN A;  5ID7 A;  5ID9 A;  1KXP D;  5IIU A;  4L8U A;  3WHQ A;  1LOT A;  3A75 A;  5IIH A;  5DBY A;  4WA6 B;  4DHX B;  1KDX A;  2NQO A;  4HGK A;  2XW0 A;  3NVK A;  4F5U A;  1TF0 A;  1GNJ A;  1E78 A;  2OZB B;  2LXS A;  3A73 A;  4LUH A;  1MIW A;  2BXQ A;  2BXB A;  4DM0 A;  3NVI A;  5IJF A;  2BXM A;  3JRY A;  4L9Q A;  3UIV A;  5IFO A;  2OT3 A;  2AJE A;  4ZC6 A;  1E7B A;  2BXH A;  3FWC C;  4LUF A;  5GIN A;  1HK5 A;  1MIY A;  3GA9 L;  2VUF A;  2EFC A;  1BJ5 A;  3B9M A;  4L9K A;  4ZBK A;  3ECP A;  4HGM B;  4TQ1 A;  1H5W A;  2DBW A;  4OTU A;  3V09 A;  1E7A A;  3JQZ A;  1HK1 A;  2DBU A;  2BXI A;  3H37 A;  2GUT A;  4NAW B;  3V03 A;  5BPK A;  2KWF A;  2XVV A;  2BXA A;  4GDL B;  3M99 C;  4J2V A;  4PO0 A;  3NVM A;  4OT2 A;  3PLA A;  2E0Y A;  1JNB A;  2XW1 A;  4F5S A;  3CX9 A;  4GDK B;  3SIU B;  4Z69 A;  4G04 A;  4ZBR A;  5IJ5 A;  2KBZ A;  3WHR A;  5IIX A;  2LOQ A;  3FWB C;  4ZUX V;  2BXF A;  2E0X A;  2BXL A;  4G01 A;  3W1S A;  2BXD A;  2DBX A;  2K0N A;  1MA9 A;  1LNS A;  2VUE A;  2QM6 A;  2XMO A;  3LU6 A;  2I2Z A;  3TDL A;  4IW1 A;  1SB0 A;  3V08 A;  2BXC A;  1J78 A;  2XSI A;  2DYO A;  4S1Y A;  4BY9 C;  1MM8 A;  2Z8I A;  1E7G A;  1HK2 A;  2VDB A;  2LXT A;  2AGH B;  4N0F D;  1E7H A;  5DQF A;  5HOZ A;  2XVQ A;  4GG2 A;  1E7C A;  3BPJ A;  3LU8 A;  4BKE A;  2DG5 A;  1O9X A;  4K71 A;  3MHS B;  1MUS A;  1HA2 A;  1H9Z A;  3B9L A;  3GQX A;  2EFE A;  2JUH A;  1AO6 A;  3LU7 A;  2BX8 A;  1KW2 A;  1GNI A;  4E99 A;  1HK4 A;  2BXO A;  3MHH B;  4C31 B;  1TXU A;  3NMU A;  2XVW A;  4ZBQ A;  4D7X A;  1N5U A;  4GDX A;  4JK4 A;  1MIV A;  1HK3 A;  3SQJ A;  5GHK A;  4FK5 B;  4K2C A;  1J7E A;  4M70 B;  3ICX A;  2V36 A;  1VFI A;  4IW2 A;  2BXG A;  2I30 A;  4N3Z A;  4F5T A;  5GIO A;  5FUO A;  4MBE C;  2CKX A;  2XVU A; 
#chains in the Genus database with same CATH homology
 2QMC A;  4FJC B;  1E7F A;  5B5T A;  4FIP B;  1E7I A;  4G03 A;  4LB9 A;  3WHS A;  2Z8K A;  1FOU A;  3G9K D;  4EMX A;  2QHB A;  2BXP A;  5GIP A;  2NNW A;  2YDF A;  1E7E A;  1BM0 A;  1IJG A;  1UOR A;  2DYM A;  4ZCG A;  4OR0 A;  5IJE A;  2ROH A;  2EFH A;  2EFD A;  4TQ0 A;  4W4U B;  4LB2 A;  1NT2 B;  1VZS A;  4Z9O A;  4F5V A;  3FNM A;  3H3A A;  3SIV B;  3KJL A;  1BKE A;  3GQU A;  2BXE A;  4OTT A;  3VQI A;  3KIK A;  2BXK A;  4LA0 A;  4N0U D;  5D7G A;  2Z8J A;  2BXN A;  5ID7 A;  5ID9 A;  1KXP D;  5IIU A;  4L8U A;  3WHQ A;  1LOT A;  3A75 A;  5IIH A;  5DBY A;  4WA6 B;  4DHX B;  2NQO A;  4HGK A;  2XW0 A;  3NVK A;  4F5U A;  1TF0 A;  1GNJ A;  1E78 A;  2OZB B;  4LUH A;  3A73 A;  1MIW A;  2BXQ A;  2BXB A;  3NVI A;  5IJF A;  2BXM A;  3JRY A;  4L9Q A;  3UIV A;  5IFO A;  2OT3 A;  2AJE A;  4ZC6 A;  1E7B A;  2BXH A;  3FWC C;  4LUF A;  5GIN A;  1HK5 A;  1MIY A;  3GA9 L;  2VUF A;  2EFC A;  1BJ5 A;  3B9M A;  4L9K A;  4ZBK A;  4HGM B;  4TQ1 A;  1H5W A;  2DBW A;  4OTU A;  3V09 A;  1E7A A;  3JQZ A;  1HK1 A;  2DBU A;  2BXI A;  3H37 A;  5BPK A;  4NAW B;  3V03 A;  2XVV A;  2BXA A;  4GDL B;  3M99 C;  4J2V A;  4PO0 A;  3NVM A;  4OT2 A;  3PLA A;  2E0Y A;  1JNB A;  2XW1 A;  4F5S A;  3CX9 A;  4GDK B;  3SIU B;  4Z69 A;  4G04 A;  4ZBR A;  5IJ5 A;  2KBZ A;  3WHR A;  5IIX A;  2LOQ A;  3FWB C;  4ZUX V;  2BXF A;  2E0X A;  2BXL A;  4G01 A;  3W1S A;  2BXD A;  2DBX A;  1MA9 A;  1LNS A;  2VUE A;  2QM6 A;  2XMO A;  3LU6 A;  2I2Z A;  3TDL A;  4IW1 A;  3V08 A;  2BXC A;  1J78 A;  2XSI A;  2DYO A;  4S1Y A;  4BY9 C;  2Z8I A;  1E7G A;  1HK2 A;  2VDB A;  4N0F D;  1E7H A;  5DQF A;  5HOZ A;  2XVQ A;  4GG2 A;  1E7C A;  4BKE A;  3LU8 A;  2DG5 A;  1O9X A;  4K71 A;  3MHS B;  1HA2 A;  1H9Z A;  3B9L A;  3GQX A;  2EFE A;  2JUH A;  1AO6 A;  3LU7 A;  2BX8 A;  1KW2 A;  1GNI A;  4E99 A;  1HK4 A;  2BXO A;  3MHH B;  4C31 B;  1TXU A;  3NMU A;  2XVW A;  4ZBQ A;  1N5U A;  4GDX A;  4JK4 A;  1MIV A;  1HK3 A;  3SQJ A;  5GHK A;  4FK5 B;  4K2C A;  1J7E A;  4M70 B;  3ICX A;  2V36 A;  1VFI A;  4IW2 A;  2BXG A;  2I30 A;  4N3Z A;  4F5T A;  5GIO A;  5FUO A;  4MBE C;  2CKX A;  2XVU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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