2BXFA

Human serum albumin complexed with diazepam
Total Genus 207
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
207
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 207
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxfA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxfA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxfA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxfA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxfA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxfA05
2XSIA 5ID9A 3A73A 3V08A 1LOTA 2XVWA 1HA2A 1KW2A 1KXPD 4OR0A 4Z69A 2YDFA 3SQJA 2BXDA 1GNJA 2BXCA 2I2ZA 1E7HA 3B9LA 2BXFA 2BX8A 2BXQA 3V03A 4J2VA 4LA0A 2XW1A 1O9XA 1E7AA 5IIHA 5IIUA 1HK5A 2BXAA 5ID7A 4S1YA 2BXMA 1E7GA 2VDBA 4G04A 1E7IA 2BXIA 5IFOA 4L9KA 4LUFA 1GNIA 1TF0A 1J7EA 2BXOA 3LU7A 4EMXA 3V09A 1HK4A 1BJ5A 3JRYA 2BXHA 4LB2A 1N5UA 1HK2A 2XW0A 4BKEA 4K2CA 5IJFA 5IIXA 2BXPA 2VUFA 4F5UA 1BM0A 1E78A 2BXGA 1E7CA 4E99A 4ZBQA 3B9MA 4JK4A 4F5TA 1HK3A 3LU8A 4G03A 4HGKA 1E7EA 4F5VA 5IJ5A 2BXNA 2I30A 2BXKA 3TDLA 4IW2A 5HOZA 4PO0A 1HK1A 5FUOA 4N0UD 4IW1A 5DQFA 5GHKA 1AO6A 2BXLA 4K71A 5DBYA 4L9QA 3UIVA 2XVQA 3CX9A 4ZBRA 4LB9A 2VUEA 4LUHA 4HGMB 5IJEA 4N0FD 4L8UA 4OT2A 4F5SA 1H9ZA 3JQZA 2BXBA 1E7FA 1BKEA 3LU6A 1J78A 1E7BA 2BXEA 2XVUA 2XVVA 1MA9A 1UORA
chains in the Genus database with same CATH superfamily
1JNBA 2XSIA 2E0XA 4GDKB 4OTUA 5ID9A 3A73A 3V08A 1LOTA 4BY9C 2XVWA 1HA2A 1KW2A 1KXPD 4OR0A 4Z69A 2YDFA 1NT2B 3WHQA 3SQJA 2BXDA 3MHHB 1GNJA 4DM0A 2BXCA 2I2ZA 1E7HA 3B9LA 2DBXA 2BXFA 4DHXB 4Z9OA 2BX8A 3G9KD 2BXQA 4C31B 3V03A 1KDXA 4J2VA 3H37A 3NVIA 1LNSA 5GIOA 2K0NA 3VQIA 3WHRA 4GDLB 3W1SA 4LA0A 2XW1A 2LQHA 1O9XA 1E7AA 5IIHA 5IIUA 1HK5A 2BXAA 5ID7A 1TXUA 3FNMA 4WA6B 4S1YA 2EFDA 2BXMA 4D7XA 1MM8A 2DYOA 1E7GA 2VDBA 2Z8KA 2KBZA 1MUSA 2KWFA 2LXTA 3H3AA 1E7IA 2BXIA 4G04A 5IFOA 5GIPA 3NMUA 4L9KA 4LUFA 2QMCA 2E0YA 2EFEA 3GQUA 1GNIA 1TF0A 3SIVB 2DG5A 1J7EA 2BXOA 2XMOA 3LU7A 1FOUA 4EMXA 2NNWA 3V09A 4W4UB 1HK4A 3BPJA 2EFHA 1BJ5A 3NVKA 3JRYA 2QM6A 3GQXA 3NVMA 2BXHA 4FJCB 4LB2A 1N5UA 3SIUB 1VFIA 1HK2A 2XW0A 3FWBC 1MUHA 3ECPA 4FK5B 4M70B 4BKEA 4ZCGA 4K2CA 5IJFA 5IIXA 2DYMA 2BXPA 4GDXA 2VUFA 4ZUXV 4F5UA 5B5TA 1BM0A 1E78A 3GA9L 2NQOA 2Z8JA 2BXGA 1E7CA 4E99A 4ZBQA 3B9MA 4TQ0A 2QHBA 4JK4A 4F5TA 4ZBKA 1HK3A 2ROHA 3LU8A 2V36A 4G03A 1E7EA 4HGKA 2EFCA 2OT3A 4GG2A 4F5VA 5IJ5A 2BXNA 2I30A 2Z8IA 2BXKA 1SB0A 3TDLA 4IW2A 5BPKA 5HOZA 4PO0A 1HK1A 4FIPB 5FUOA 4N0UD 4IW1A 5DQFA 3FWCC 2DBWA 4G01A 5GHKA 1AO6A 2AGHB 2BXLA 4K71A 2AJEA 2LXSA 2DBUA 4OTTA 1MIVA 2LQIA 3M99C 3KIKA 5DBYA 4L9QA 3UIVA 2XVQA 3CX9A 4MBEC 2GUTA 2JUHA 4ZBRA 4LB9A 2VUEA 2OZBB 1MIWA 5GINA 4LUHA 4HGMB 4NAWB 5IJEA 3KJLA 4N0FD 2CKXA 3ICXA 4L8UA 4ZC6A 4OT2A 4F5SA 2LOQA 3A75A 1H9ZA 3JQZA 3MHSB 4I9OA 2BXBA 4N3ZA 1MIYA 1E7FA 1VZSA 5D7GA 1IJGA 1BKEA 1H5WA 3WHSA 3LU6A 1J78A 1E7BA 2BXEA 2XVUA 2XVVA 4TQ1A 3PLAA 1MA9A 1UORA
chains in the Genus database with same CATH topology
1JNBA 2XSIA 2E0XA 4GDKB 4OTUA 5ID9A 3A73A 3V08A 1LOTA 4BY9C 2XVWA 1HA2A 1KW2A 1KXPD 4OR0A 4Z69A 2YDFA 1NT2B 3WHQA 3SQJA 2BXDA 3MHHB 1GNJA 2BXCA 2I2ZA 1E7HA 3B9LA 2DBXA 2BXFA 4DHXB 4Z9OA 2BX8A 3G9KD 2BXQA 4C31B 3V03A 4J2VA 3H37A 3NVIA 1LNSA 5GIOA 3VQIA 3WHRA 4GDLB 3W1SA 4LA0A 2XW1A 1O9XA 1E7AA 5IIHA 5IIUA 1HK5A 2BXAA 5ID7A 1TXUA 3FNMA 4WA6B 4S1YA 2EFDA 2BXMA 2DYOA 1E7GA 2VDBA 2Z8KA 2KBZA 3H3AA 4G04A 1E7IA 2BXIA 5IFOA 5GIPA 3NMUA 4L9KA 4LUFA 2QMCA 2E0YA 2EFEA 3GQUA 1GNIA 1TF0A 3SIVB 2DG5A 1J7EA 2BXOA 2XMOA 3LU7A 1FOUA 4EMXA 2NNWA 3V09A 4W4UB 1HK4A 2EFHA 1BJ5A 3NVKA 3JRYA 2QM6A 3GQXA 3NVMA 2BXHA 4FJCB 4LB2A 1N5UA 3SIUB 1VFIA 1HK2A 2XW0A 3FWBC 4FK5B 4M70B 4BKEA 4ZCGA 4K2CA 5IJFA 5IIXA 2DYMA 2BXPA 4GDXA 2VUFA 4ZUXV 4F5UA 5B5TA 1BM0A 1E78A 3GA9L 2NQOA 2Z8JA 2BXGA 1E7CA 4E99A 4ZBQA 3B9MA 4TQ0A 2QHBA 4JK4A 4F5TA 4ZBKA 1HK3A 2ROHA 3LU8A 2V36A 4G03A 1E7EA 4HGKA 2EFCA 2OT3A 4GG2A 4F5VA 5IJ5A 2BXNA 2I30A 2Z8IA 2BXKA 3TDLA 4IW2A 5BPKA 5HOZA 4PO0A 1HK1A 4FIPB 5FUOA 4N0UD 4IW1A 5DQFA 3FWCC 2DBWA 4G01A 5GHKA 1AO6A 2BXLA 4K71A 2AJEA 2DBUA 4OTTA 1MIVA 3M99C 3KIKA 5DBYA 4L9QA 3UIVA 2XVQA 3CX9A 4MBEC 2JUHA 4ZBRA 4LB9A 2VUEA 2OZBB 1MIWA 5GINA 4LUHA 4HGMB 4NAWB 5IJEA 3KJLA 4N0FD 2CKXA 3ICXA 4L8UA 4ZC6A 4OT2A 4F5SA 2LOQA 3A75A 1H9ZA 3JQZA 3MHSB 2BXBA 4N3ZA 1MIYA 1E7FA 1VZSA 5D7GA 1IJGA 1BKEA 1H5WA 3WHSA 3LU6A 1J78A 1E7BA 2BXEA 2XVUA 2XVVA 4TQ1A 3PLAA 1MA9A 1UORA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XSI A;  5ID9 A;  3A73 A;  3V08 A;  1LOT A;  2XVW A;  1HA2 A;  1KW2 A;  1KXP D;  4OR0 A;  4Z69 A;  2YDF A;  3SQJ A;  2BXD A;  1GNJ A;  2BXC A;  2I2Z A;  1E7H A;  3B9L A;  2BXF A;  2BX8 A;  2BXQ A;  3V03 A;  4J2V A;  4LA0 A;  2XW1 A;  1O9X A;  1E7A A;  5IIH A;  5IIU A;  1HK5 A;  2BXA A;  5ID7 A;  4S1Y A;  2BXM A;  1E7G A;  2VDB A;  4G04 A;  1E7I A;  2BXI A;  5IFO A;  4L9K A;  4LUF A;  1GNI A;  1TF0 A;  1J7E A;  2BXO A;  3LU7 A;  4EMX A;  3V09 A;  1HK4 A;  1BJ5 A;  3JRY A;  2BXH A;  4LB2 A;  1N5U A;  1HK2 A;  2XW0 A;  4BKE A;  4K2C A;  5IJF A;  5IIX A;  2BXP A;  2VUF A;  4F5U A;  1BM0 A;  1E78 A;  2BXG A;  1E7C A;  4E99 A;  4ZBQ A;  3B9M A;  4JK4 A;  4F5T A;  1HK3 A;  3LU8 A;  4G03 A;  4HGK A;  1E7E A;  4F5V A;  5IJ5 A;  2BXN A;  2I30 A;  2BXK A;  3TDL A;  4IW2 A;  5HOZ A;  4PO0 A;  1HK1 A;  5FUO A;  4N0U D;  4IW1 A;  5DQF A;  5GHK A;  1AO6 A;  2BXL A;  4K71 A;  5DBY A;  4L9Q A;  3UIV A;  2XVQ A;  3CX9 A;  4ZBR A;  4LB9 A;  2VUE A;  4LUH A;  4HGM B;  5IJE A;  4N0F D;  4L8U A;  4OT2 A;  4F5S A;  1H9Z A;  3JQZ A;  2BXB A;  1E7F A;  1BKE A;  3LU6 A;  1J78 A;  1E7B A;  2BXE A;  2XVU A;  2XVV A;  1MA9 A;  1UOR A; 
#chains in the Genus database with same CATH topology
 1JNB A;  2XSI A;  2E0X A;  4GDK B;  4OTU A;  5ID9 A;  3A73 A;  3V08 A;  1LOT A;  4BY9 C;  2XVW A;  1HA2 A;  1KW2 A;  1KXP D;  4OR0 A;  4Z69 A;  2YDF A;  1NT2 B;  3WHQ A;  3SQJ A;  2BXD A;  3MHH B;  1GNJ A;  4DM0 A;  2BXC A;  2I2Z A;  1E7H A;  3B9L A;  2DBX A;  2BXF A;  4DHX B;  4Z9O A;  2BX8 A;  3G9K D;  2BXQ A;  4C31 B;  3V03 A;  1KDX A;  4J2V A;  3H37 A;  3NVI A;  1LNS A;  5GIO A;  2K0N A;  3VQI A;  3WHR A;  4GDL B;  3W1S A;  4LA0 A;  2XW1 A;  2LQH A;  1O9X A;  1E7A A;  5IIH A;  5IIU A;  1HK5 A;  2BXA A;  5ID7 A;  1TXU A;  3FNM A;  4WA6 B;  4S1Y A;  2EFD A;  2BXM A;  4D7X A;  1MM8 A;  2DYO A;  1E7G A;  2VDB A;  2Z8K A;  2KBZ A;  1MUS A;  2KWF A;  2LXT A;  3H3A A;  1E7I A;  2BXI A;  4G04 A;  5IFO A;  5GIP A;  3NMU A;  4L9K A;  4LUF A;  2QMC A;  2E0Y A;  2EFE A;  3GQU A;  1GNI A;  1TF0 A;  3SIV B;  2DG5 A;  1J7E A;  2BXO A;  2XMO A;  3LU7 A;  1FOU A;  4EMX A;  2NNW A;  3V09 A;  4W4U B;  1HK4 A;  3BPJ A;  2EFH A;  1BJ5 A;  3NVK A;  3JRY A;  2QM6 A;  3GQX A;  3NVM A;  2BXH A;  4FJC B;  4LB2 A;  1N5U A;  3SIU B;  1VFI A;  1HK2 A;  2XW0 A;  3FWB C;  1MUH A;  3ECP A;  4FK5 B;  4M70 B;  4BKE A;  4ZCG A;  4K2C A;  5IJF A;  5IIX A;  2DYM A;  2BXP A;  4GDX A;  2VUF A;  4ZUX V;  4F5U A;  5B5T A;  1BM0 A;  1E78 A;  3GA9 L;  2NQO A;  2Z8J A;  2BXG A;  1E7C A;  4E99 A;  4ZBQ A;  3B9M A;  4TQ0 A;  2QHB A;  4JK4 A;  4F5T A;  4ZBK A;  1HK3 A;  2ROH A;  3LU8 A;  2V36 A;  4G03 A;  1E7E A;  4HGK A;  2EFC A;  2OT3 A;  4GG2 A;  4F5V A;  5IJ5 A;  2BXN A;  2I30 A;  2Z8I A;  2BXK A;  1SB0 A;  3TDL A;  4IW2 A;  5BPK A;  5HOZ A;  4PO0 A;  1HK1 A;  4FIP B;  5FUO A;  4N0U D;  4IW1 A;  5DQF A;  3FWC C;  2DBW A;  4G01 A;  5GHK A;  1AO6 A;  2AGH B;  2BXL A;  4K71 A;  2AJE A;  2LXS A;  2DBU A;  4OTT A;  1MIV A;  2LQI A;  3M99 C;  3KIK A;  5DBY A;  4L9Q A;  3UIV A;  2XVQ A;  3CX9 A;  4MBE C;  2GUT A;  2JUH A;  4ZBR A;  4LB9 A;  2VUE A;  2OZB B;  1MIW A;  5GIN A;  4LUH A;  4HGM B;  4NAW B;  5IJE A;  3KJL A;  4N0F D;  2CKX A;  3ICX A;  4L8U A;  4ZC6 A;  4OT2 A;  4F5S A;  2LOQ A;  3A75 A;  1H9Z A;  3JQZ A;  3MHS B;  4I9O A;  2BXB A;  4N3Z A;  1MIY A;  1E7F A;  1VZS A;  5D7G A;  1IJG A;  1BKE A;  1H5W A;  3WHS A;  3LU6 A;  1J78 A;  1E7B A;  2BXE A;  2XVU A;  2XVV A;  4TQ1 A;  3PLA A;  1MA9 A;  1UOR A; 
#chains in the Genus database with same CATH homology
 1JNB A;  2XSI A;  2E0X A;  4GDK B;  4OTU A;  5ID9 A;  3A73 A;  3V08 A;  1LOT A;  4BY9 C;  2XVW A;  1HA2 A;  1KW2 A;  1KXP D;  4OR0 A;  4Z69 A;  2YDF A;  1NT2 B;  3WHQ A;  3SQJ A;  2BXD A;  3MHH B;  1GNJ A;  2BXC A;  2I2Z A;  1E7H A;  3B9L A;  2DBX A;  2BXF A;  4DHX B;  4Z9O A;  2BX8 A;  3G9K D;  2BXQ A;  4C31 B;  3V03 A;  4J2V A;  3H37 A;  3NVI A;  1LNS A;  5GIO A;  3VQI A;  3WHR A;  4GDL B;  3W1S A;  4LA0 A;  2XW1 A;  1O9X A;  1E7A A;  5IIH A;  5IIU A;  1HK5 A;  2BXA A;  5ID7 A;  1TXU A;  3FNM A;  4WA6 B;  4S1Y A;  2EFD A;  2BXM A;  2DYO A;  1E7G A;  2VDB A;  2Z8K A;  2KBZ A;  3H3A A;  4G04 A;  1E7I A;  2BXI A;  5IFO A;  5GIP A;  3NMU A;  4L9K A;  4LUF A;  2QMC A;  2E0Y A;  2EFE A;  3GQU A;  1GNI A;  1TF0 A;  3SIV B;  2DG5 A;  1J7E A;  2BXO A;  2XMO A;  3LU7 A;  1FOU A;  4EMX A;  2NNW A;  3V09 A;  4W4U B;  1HK4 A;  2EFH A;  1BJ5 A;  3NVK A;  3JRY A;  2QM6 A;  3GQX A;  3NVM A;  2BXH A;  4FJC B;  4LB2 A;  1N5U A;  3SIU B;  1VFI A;  1HK2 A;  2XW0 A;  3FWB C;  4FK5 B;  4M70 B;  4BKE A;  4ZCG A;  4K2C A;  5IJF A;  5IIX A;  2DYM A;  2BXP A;  4GDX A;  2VUF A;  4ZUX V;  4F5U A;  5B5T A;  1BM0 A;  1E78 A;  3GA9 L;  2NQO A;  2Z8J A;  2BXG A;  1E7C A;  4E99 A;  4ZBQ A;  3B9M A;  4TQ0 A;  2QHB A;  4JK4 A;  4F5T A;  4ZBK A;  1HK3 A;  2ROH A;  3LU8 A;  2V36 A;  4G03 A;  1E7E A;  4HGK A;  2EFC A;  2OT3 A;  4GG2 A;  4F5V A;  5IJ5 A;  2BXN A;  2I30 A;  2Z8I A;  2BXK A;  3TDL A;  4IW2 A;  5BPK A;  5HOZ A;  4PO0 A;  1HK1 A;  4FIP B;  5FUO A;  4N0U D;  4IW1 A;  5DQF A;  3FWC C;  2DBW A;  4G01 A;  5GHK A;  1AO6 A;  2BXL A;  4K71 A;  2AJE A;  2DBU A;  4OTT A;  1MIV A;  3M99 C;  3KIK A;  5DBY A;  4L9Q A;  3UIV A;  2XVQ A;  3CX9 A;  4MBE C;  2JUH A;  4ZBR A;  4LB9 A;  2VUE A;  2OZB B;  1MIW A;  5GIN A;  4LUH A;  4HGM B;  4NAW B;  5IJE A;  3KJL A;  4N0F D;  2CKX A;  3ICX A;  4L8U A;  4ZC6 A;  4OT2 A;  4F5S A;  2LOQ A;  3A75 A;  1H9Z A;  3JQZ A;  3MHS B;  2BXB A;  4N3Z A;  1MIY A;  1E7F A;  1VZS A;  5D7G A;  1IJG A;  1BKE A;  1H5W A;  3WHS A;  3LU6 A;  1J78 A;  1E7B A;  2BXE A;  2XVU A;  2XVV A;  4TQ1 A;  3PLA A;  1MA9 A;  1UOR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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