2BXHA

Human serum albumin complexed with indoxyl sulfate
Total Genus 206
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
206
sequence length
557
structure length
557
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 206
structure length 557
sequence length 557
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA05
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxhA06
2BXGA 1BM0A 1E7BA 1E7GA 2BXFA 4OT2A 4K2CA 4LB2A 1LOTA 4LUHA 1AO6A 3LU8A 4ZBRA 1GNJA 2BXLA 4EMXA 4IW2A 2BXNA 1KW2A 4BKEA 2BXDA 2BXHA 4LB9A 4LUFA 1TF0A 2BXEA 2XVVA 1E7CA 5FUOA 1HA2A 3B9MA 2XW1A 4S1YA 3A73A 4L9KA 2BXCA 1KXPD 1E7IA 2BX8A 4F5VA 5HOZA 4OR0A 4HGKA 1E7FA 2XVWA 1GNIA 3UIVA 2VUEA 2YDFA 1E7EA 2BXQA 2VUFA 4F5UA 2VDBA 1BKEA 4HGMB 1BJ5A 1HK1A 4N0UD 1UORA 1MA9A 3SQJA 1HK5A 2XSIA 1HK3A 5IJFA 5DBYA 1E7HA 3LU7A 3V03A 1HK4A 3JRYA 4G04A 4E99A 3TDLA 2I2ZA 4G03A 4LA0A 1N5UA 4N0FD 2XW0A 5DQFA 4L9QA 3JQZA 3V08A 4J2VA 4IW1A 2XVUA 5IIUA 2BXPA 5ID7A 5GHKA 5IFOA 1H9ZA 2BXBA 1O9XA 3B9LA 4F5SA 5ID9A 2I30A 4F5TA 5IIXA 1J78A 1HK2A 1E78A 4JK4A 5IJEA 1J7EA 5IJ5A 2BXIA 2XVQA 1E7AA 2BXAA 4ZBQA 2BXOA 4K71A 3LU6A 4PO0A 2BXKA 4Z69A 5IIHA 3V09A 2BXMA 4L8UA 3CX9A
chains in the Genus database with same CATH superfamily
2BXGA 2OT3A 1BM0A 1E7BA 1E7GA 2BXFA 4OT2A 1KDXA 4K2CA 4OTUA 2NQOA 1LOTA 4LB2A 5GINA 4LUHA 1JNBA 4N3ZA 1MIWA 1AO6A 2OZBB 3LU8A 4ZBRA 3VQIA 2LXTA 1GNJA 1VFIA 2BXLA 4EMXA 4IW2A 2BXNA 1KW2A 4BKEA 3PLAA 1SB0A 2BXDA 2LQIA 2BXHA 4LB9A 2XMOA 2DBUA 4LUFA 2LQHA 1TF0A 2BXEA 1IJGA 4M70B 2XVVA 4D7XA 3WHQA 1E7CA 1H5WA 3KIKA 5FUOA 2JUHA 5D7GA 2K0NA 2EFCA 3BPJA 4I9OA 2KBZA 4WA6B 1HA2A 3B9MA 4FJCB 2AJEA 2XW1A 3NMUA 2E0YA 2LOQA 4S1YA 4DHXB 4W4UB 3A73A 4G01A 2BXCA 4L9KA 3H37A 1KXPD 1E7IA 3MHHB 2BX8A 4ZBKA 2CKXA 1MIVA 2V36A 1NT2B 4F5VA 2Z8JA 2Z8KA 5HOZA 3G9KD 2DYOA 5GIOA 2DG5A 4OR0A 4HGKA 1E7FA 3H3AA 3GQUA 2XVWA 1GNIA 3UIVA 2KWFA 3WHSA 1MUSA 1MUHA 2DYMA 4FK5B 3SIUB 2VUEA 1TXUA 1E7EA 2BXQA 2YDFA 2VUFA 2EFDA 4F5UA 1VZSA 2EFHA 1BKEA 2VDBA 4NAWB 1BJ5A 4HGMB 1HK1A 4N0UD 1UORA 1MA9A 2E0XA 3SQJA 1HK5A 2DBXA 2XSIA 1HK3A 5IJFA 5DBYA 1E7HA 3LU7A 4MBEC 3V03A 1HK4A 5BPKA 3JRYA 4G04A 4ZC6A 4BY9C 2QHBA 4E99A 3TDLA 2I2ZA 3MHSB 4ZUXV 2QM6A 5GIPA 3KJLA 4G03A 4LA0A 1N5UA 4N0FD 2DBWA 3SIVB 2XW0A 5DQFA 4L9QA 2GUTA 2LXSA 4OTTA 4Z9OA 3GQXA 4GDXA 2NNWA 4DM0A 2ROHA 3JQZA 3V08A 4J2VA 3FNMA 4IW1A 3GA9L 3M99C 3NVIA 1MM8A 2XVUA 5IIUA 3NVKA 2BXPA 5ID7A 4ZCGA 5GHKA 2EFEA 5IFOA 4C31B 1H9ZA 2BXBA 4TQ0A 3WHRA 2QMCA 4GDKB 1MIYA 1O9XA 3B9LA 4F5SA 5ID9A 2I30A 3ICXA 4F5TA 5IIXA 1LNSA 1J78A 1HK2A 3FWCC 4GDLB 4GG2A 1E78A 3ECPA 4JK4A 5IJEA 2AGHB 3NVMA 1J7EA 5IJ5A 2BXIA 3W1SA 1FOUA 2XVQA 3FWBC 1E7AA 2BXAA 4ZBQA 2BXOA 4FIPB 4K71A 4TQ1A 2Z8IA 3LU6A 4PO0A 2BXKA 3A75A 4Z69A 5IIHA 3V09A 2BXMA 4L8UA 3CX9A 5B5TA
chains in the Genus database with same CATH topology
2BXGA 2OT3A 1BM0A 1E7BA 1E7GA 2BXFA 4OT2A 4K2CA 4OTUA 2NQOA 1LOTA 4LB2A 5GINA 4LUHA 1JNBA 4N3ZA 1MIWA 1AO6A 2OZBB 3LU8A 4ZBRA 3VQIA 1GNJA 1VFIA 2BXLA 4EMXA 4IW2A 2BXNA 1KW2A 4BKEA 3PLAA 2BXDA 2BXHA 4LB9A 2XMOA 2DBUA 4LUFA 1TF0A 2BXEA 1IJGA 4M70B 2XVVA 3WHQA 1E7CA 1H5WA 3KIKA 5FUOA 2JUHA 5D7GA 2EFCA 4WA6B 3NMUA 2KBZA 1HA2A 3B9MA 4FJCB 2AJEA 2XW1A 2E0YA 2LOQA 4S1YA 4DHXB 4W4UB 3A73A 4G01A 2BXCA 4L9KA 3H37A 1KXPD 1E7IA 3MHHB 2BX8A 4ZBKA 2CKXA 1MIVA 2V36A 1NT2B 4F5VA 2Z8JA 2Z8KA 5HOZA 3G9KD 2DYOA 5GIOA 2DG5A 4OR0A 4HGKA 1E7FA 3H3AA 3GQUA 2XVWA 1GNIA 3UIVA 3WHSA 3SIUB 2DYMA 4FK5B 2VUEA 1TXUA 1E7EA 2BXQA 2YDFA 2VUFA 2EFDA 4F5UA 1VZSA 2EFHA 1BKEA 2VDBA 4NAWB 1BJ5A 4HGMB 1HK1A 4N0UD 1UORA 1MA9A 2E0XA 3SQJA 1HK5A 2DBXA 2XSIA 1HK3A 5IJFA 5DBYA 1E7HA 3LU7A 4MBEC 3V03A 1HK4A 5BPKA 3JRYA 4G04A 4ZC6A 4BY9C 2QHBA 4E99A 3TDLA 2I2ZA 3MHSB 4ZUXV 2QM6A 5GIPA 3KJLA 4G03A 4LA0A 1N5UA 4N0FD 2DBWA 3SIVB 2XW0A 5DQFA 4L9QA 4OTTA 4Z9OA 3GQXA 4GDXA 2NNWA 2ROHA 3JQZA 3V08A 4J2VA 3FNMA 4IW1A 3GA9L 3M99C 3NVIA 2XVUA 5IIUA 3NVKA 2BXPA 5ID7A 4ZCGA 5GHKA 2EFEA 5IFOA 4C31B 1H9ZA 2BXBA 4TQ0A 3WHRA 2QMCA 4GDKB 1MIYA 1O9XA 3B9LA 4F5SA 5ID9A 2I30A 3ICXA 4F5TA 5IIXA 1LNSA 1J78A 1HK2A 3FWCC 4GDLB 4GG2A 1E78A 4JK4A 5IJEA 3NVMA 1J7EA 5IJ5A 2BXIA 3W1SA 1FOUA 2XVQA 3FWBC 1E7AA 2BXAA 4ZBQA 2BXOA 4FIPB 4K71A 4TQ1A 2Z8IA 3LU6A 4PO0A 2BXKA 3A75A 4Z69A 5IIHA 3V09A 2BXMA 4L8UA 3CX9A 5B5TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXG A;  1BM0 A;  1E7B A;  1E7G A;  2BXF A;  4OT2 A;  4K2C A;  4LB2 A;  1LOT A;  4LUH A;  1AO6 A;  3LU8 A;  4ZBR A;  1GNJ A;  2BXL A;  4EMX A;  4IW2 A;  2BXN A;  1KW2 A;  4BKE A;  2BXD A;  2BXH A;  4LB9 A;  4LUF A;  1TF0 A;  2BXE A;  2XVV A;  1E7C A;  5FUO A;  1HA2 A;  3B9M A;  2XW1 A;  4S1Y A;  3A73 A;  4L9K A;  2BXC A;  1KXP D;  1E7I A;  2BX8 A;  4F5V A;  5HOZ A;  4OR0 A;  4HGK A;  1E7F A;  2XVW A;  1GNI A;  3UIV A;  2VUE A;  2YDF A;  1E7E A;  2BXQ A;  2VUF A;  4F5U A;  2VDB A;  1BKE A;  4HGM B;  1BJ5 A;  1HK1 A;  4N0U D;  1UOR A;  1MA9 A;  3SQJ A;  1HK5 A;  2XSI A;  1HK3 A;  5IJF A;  5DBY A;  1E7H A;  3LU7 A;  3V03 A;  1HK4 A;  3JRY A;  4G04 A;  4E99 A;  3TDL A;  2I2Z A;  4G03 A;  4LA0 A;  1N5U A;  4N0F D;  2XW0 A;  5DQF A;  4L9Q A;  3JQZ A;  3V08 A;  4J2V A;  4IW1 A;  2XVU A;  5IIU A;  2BXP A;  5ID7 A;  5GHK A;  5IFO A;  1H9Z A;  2BXB A;  1O9X A;  3B9L A;  4F5S A;  5ID9 A;  2I30 A;  4F5T A;  5IIX A;  1J78 A;  1HK2 A;  1E78 A;  4JK4 A;  5IJE A;  1J7E A;  5IJ5 A;  2BXI A;  2XVQ A;  1E7A A;  2BXA A;  4ZBQ A;  2BXO A;  4K71 A;  3LU6 A;  4PO0 A;  2BXK A;  4Z69 A;  5IIH A;  3V09 A;  2BXM A;  4L8U A;  3CX9 A; 
#chains in the Genus database with same CATH topology
 2BXG A;  2OT3 A;  1BM0 A;  1E7B A;  1E7G A;  2BXF A;  4OT2 A;  1KDX A;  4K2C A;  4OTU A;  2NQO A;  1LOT A;  4LB2 A;  5GIN A;  4LUH A;  1JNB A;  4N3Z A;  1MIW A;  1AO6 A;  2OZB B;  3LU8 A;  4ZBR A;  3VQI A;  2LXT A;  1GNJ A;  1VFI A;  2BXL A;  4EMX A;  4IW2 A;  2BXN A;  1KW2 A;  4BKE A;  3PLA A;  1SB0 A;  2BXD A;  2LQI A;  2BXH A;  4LB9 A;  2XMO A;  2DBU A;  4LUF A;  2LQH A;  1TF0 A;  2BXE A;  1IJG A;  4M70 B;  2XVV A;  4D7X A;  3WHQ A;  1E7C A;  1H5W A;  3KIK A;  5FUO A;  2JUH A;  5D7G A;  2K0N A;  2EFC A;  3BPJ A;  4I9O A;  2KBZ A;  4WA6 B;  1HA2 A;  3B9M A;  4FJC B;  2AJE A;  2XW1 A;  3NMU A;  2E0Y A;  2LOQ A;  4S1Y A;  4DHX B;  4W4U B;  3A73 A;  4G01 A;  2BXC A;  4L9K A;  3H37 A;  1KXP D;  1E7I A;  3MHH B;  2BX8 A;  4ZBK A;  2CKX A;  1MIV A;  2V36 A;  1NT2 B;  4F5V A;  2Z8J A;  2Z8K A;  5HOZ A;  3G9K D;  2DYO A;  5GIO A;  2DG5 A;  4OR0 A;  4HGK A;  1E7F A;  3H3A A;  3GQU A;  2XVW A;  1GNI A;  3UIV A;  2KWF A;  3WHS A;  1MUS A;  1MUH A;  2DYM A;  4FK5 B;  3SIU B;  2VUE A;  1TXU A;  1E7E A;  2BXQ A;  2YDF A;  2VUF A;  2EFD A;  4F5U A;  1VZS A;  2EFH A;  1BKE A;  2VDB A;  4NAW B;  1BJ5 A;  4HGM B;  1HK1 A;  4N0U D;  1UOR A;  1MA9 A;  2E0X A;  3SQJ A;  1HK5 A;  2DBX A;  2XSI A;  1HK3 A;  5IJF A;  5DBY A;  1E7H A;  3LU7 A;  4MBE C;  3V03 A;  1HK4 A;  5BPK A;  3JRY A;  4G04 A;  4ZC6 A;  4BY9 C;  2QHB A;  4E99 A;  3TDL A;  2I2Z A;  3MHS B;  4ZUX V;  2QM6 A;  5GIP A;  3KJL A;  4G03 A;  4LA0 A;  1N5U A;  4N0F D;  2DBW A;  3SIV B;  2XW0 A;  5DQF A;  4L9Q A;  2GUT A;  2LXS A;  4OTT A;  4Z9O A;  3GQX A;  4GDX A;  2NNW A;  4DM0 A;  2ROH A;  3JQZ A;  3V08 A;  4J2V A;  3FNM A;  4IW1 A;  3GA9 L;  3M99 C;  3NVI A;  1MM8 A;  2XVU A;  5IIU A;  3NVK A;  2BXP A;  5ID7 A;  4ZCG A;  5GHK A;  2EFE A;  5IFO A;  4C31 B;  1H9Z A;  2BXB A;  4TQ0 A;  3WHR A;  2QMC A;  4GDK B;  1MIY A;  1O9X A;  3B9L A;  4F5S A;  5ID9 A;  2I30 A;  3ICX A;  4F5T A;  5IIX A;  1LNS A;  1J78 A;  1HK2 A;  3FWC C;  4GDL B;  4GG2 A;  1E78 A;  3ECP A;  4JK4 A;  5IJE A;  2AGH B;  3NVM A;  1J7E A;  5IJ5 A;  2BXI A;  3W1S A;  1FOU A;  2XVQ A;  3FWB C;  1E7A A;  2BXA A;  4ZBQ A;  2BXO A;  4FIP B;  4K71 A;  4TQ1 A;  2Z8I A;  3LU6 A;  4PO0 A;  2BXK A;  3A75 A;  4Z69 A;  5IIH A;  3V09 A;  2BXM A;  4L8U A;  3CX9 A;  5B5T A; 
#chains in the Genus database with same CATH homology
 2BXG A;  2OT3 A;  1BM0 A;  1E7B A;  1E7G A;  2BXF A;  4OT2 A;  4K2C A;  4OTU A;  2NQO A;  1LOT A;  4LB2 A;  5GIN A;  4LUH A;  1JNB A;  4N3Z A;  1MIW A;  1AO6 A;  2OZB B;  3LU8 A;  4ZBR A;  3VQI A;  1GNJ A;  1VFI A;  2BXL A;  4EMX A;  4IW2 A;  2BXN A;  1KW2 A;  4BKE A;  3PLA A;  2BXD A;  2BXH A;  4LB9 A;  2XMO A;  2DBU A;  4LUF A;  1TF0 A;  2BXE A;  1IJG A;  4M70 B;  2XVV A;  3WHQ A;  1E7C A;  1H5W A;  3KIK A;  5FUO A;  2JUH A;  5D7G A;  2EFC A;  4WA6 B;  3NMU A;  2KBZ A;  1HA2 A;  3B9M A;  4FJC B;  2AJE A;  2XW1 A;  2E0Y A;  2LOQ A;  4S1Y A;  4DHX B;  4W4U B;  3A73 A;  4G01 A;  2BXC A;  4L9K A;  3H37 A;  1KXP D;  1E7I A;  3MHH B;  2BX8 A;  4ZBK A;  2CKX A;  1MIV A;  2V36 A;  1NT2 B;  4F5V A;  2Z8J A;  2Z8K A;  5HOZ A;  3G9K D;  2DYO A;  5GIO A;  2DG5 A;  4OR0 A;  4HGK A;  1E7F A;  3H3A A;  3GQU A;  2XVW A;  1GNI A;  3UIV A;  3WHS A;  3SIU B;  2DYM A;  4FK5 B;  2VUE A;  1TXU A;  1E7E A;  2BXQ A;  2YDF A;  2VUF A;  2EFD A;  4F5U A;  1VZS A;  2EFH A;  1BKE A;  2VDB A;  4NAW B;  1BJ5 A;  4HGM B;  1HK1 A;  4N0U D;  1UOR A;  1MA9 A;  2E0X A;  3SQJ A;  1HK5 A;  2DBX A;  2XSI A;  1HK3 A;  5IJF A;  5DBY A;  1E7H A;  3LU7 A;  4MBE C;  3V03 A;  1HK4 A;  5BPK A;  3JRY A;  4G04 A;  4ZC6 A;  4BY9 C;  2QHB A;  4E99 A;  3TDL A;  2I2Z A;  3MHS B;  4ZUX V;  2QM6 A;  5GIP A;  3KJL A;  4G03 A;  4LA0 A;  1N5U A;  4N0F D;  2DBW A;  3SIV B;  2XW0 A;  5DQF A;  4L9Q A;  4OTT A;  4Z9O A;  3GQX A;  4GDX A;  2NNW A;  2ROH A;  3JQZ A;  3V08 A;  4J2V A;  3FNM A;  4IW1 A;  3GA9 L;  3M99 C;  3NVI A;  2XVU A;  5IIU A;  3NVK A;  2BXP A;  5ID7 A;  4ZCG A;  5GHK A;  2EFE A;  5IFO A;  4C31 B;  1H9Z A;  2BXB A;  4TQ0 A;  3WHR A;  2QMC A;  4GDK B;  1MIY A;  1O9X A;  3B9L A;  4F5S A;  5ID9 A;  2I30 A;  3ICX A;  4F5T A;  5IIX A;  1LNS A;  1J78 A;  1HK2 A;  3FWC C;  4GDL B;  4GG2 A;  1E78 A;  4JK4 A;  5IJE A;  3NVM A;  1J7E A;  5IJ5 A;  2BXI A;  3W1S A;  1FOU A;  2XVQ A;  3FWB C;  1E7A A;  2BXA A;  4ZBQ A;  2BXO A;  4FIP B;  4K71 A;  4TQ1 A;  2Z8I A;  3LU6 A;  4PO0 A;  2BXK A;  3A75 A;  4Z69 A;  5IIH A;  3V09 A;  2BXM A;  4L8U A;  3CX9 A;  5B5T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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